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Pathways

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).

Term:glycolysis pathway
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Accession:PW:0000640 term browser browse the term
Definition:The glycolytic pathway converts the six-carbon glucose to two three-carbon pyruvate molecules. The ten reactions of glycolysis can be subdivided into an energy-consuming 'stage I' and an energy-generating 'stage II'. The net energy yield is two molecules of ATP. Pyruvate can be further oxidized via the citrate cycle, converted to lactose under anaerobic conditions or back to glucose via gluconeogenesis.
Synonyms:related_synonym: Embden-Meyerhof-Parnas pathway;   Glycolysis;   glycolytic process

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glycolysis pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss1 acyl-CoA synthetase short-chain family member 1 IEA KEGG rno:00010 NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:159,910,809...159,960,748
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 IEA KEGG rno:00010 NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide IEA KEGG rno:00010 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide IEA KEGG rno:00010 NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) IEA KEGG rno:00010 NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:229,576,636...229,607,914
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide IEA KEGG rno:00010 NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:229,421,252...229,436,691
JBrowse link
G Adpgk ADP-dependent glucokinase IEA KEGG rno:00010 NCBI chr 8:68,595,194...68,623,179
Ensembl chr 8:68,595,248...68,623,178
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 IEA KEGG rno:00010 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IEA KEGG rno:00010 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 IEA KEGG rno:00010 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 IEA KEGG rno:00010 NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 IEA KEGG rno:00010 NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEA KEGG rno:00010 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 IEA KEGG rno:00010 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 IEA KEGG rno:00010 NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 IEA KEGG rno:00010 NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 IEA KEGG rno:00010 NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 IEA KEGG rno:00010 NCBI chr13:82,038,679...82,055,478
Ensembl chr13:82,038,533...82,055,481
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A ISO
IEA
KEGG
SMPDB
RGD
PMID:5251864 SMP:00040 rno:00010, RGD:2302796 NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211
JBrowse link
G Aldoart2 aldolase 1 A retrogene 2 ISO SMPDB
RGD
PMID:5251864 RGD:2302796 SMP:00040 NCBI chr 6:78,674,945...78,676,635
Ensembl chr 6:78,673,353...78,680,406
JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO
IEA
KEGG
RGD
PMID:5251864 rno:00010, RGD:2302796 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C IEA KEGG rno:00010 NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133
JBrowse link
G Bpgm bisphosphoglycerate mutase IEA
ISO
KEGG
SMPDB
SMP:00040 rno:00010 NCBI chr 4:64,106,809...64,135,749
Ensembl chr 4:64,106,804...64,135,627
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase IEA KEGG rno:00010 NCBI chr 8:59,875,537...59,900,947
Ensembl chr 8:59,868,214...59,900,818
Ensembl chr 1:59,868,214...59,900,818
JBrowse link
G Dld dihydrolipoamide dehydrogenase IEA KEGG rno:00010 NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:53,619,631...53,652,354
JBrowse link
G Eno1 enolase 1 ISO
IEA
KEGG
SMPDB
RGD
PMID:18560153 SMP:00040 rno:00010, RGD:2302799 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003
JBrowse link
G Eno2 enolase 2 IEA KEGG rno:00010 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220
JBrowse link
G Eno3 enolase 3 IEA KEGG rno:00010 NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,866,101...55,874,540
JBrowse link
G Fbp1 fructose-bisphosphatase 1 IEA KEGG rno:00010 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
JBrowse link
G Fbp2 fructose-bisphosphatase 2 IEA KEGG rno:00010 NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 IEA
ISO
KEGG
SMPDB
SMP:00040 rno:00010 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
JBrowse link
G Galm galactose mutarotase IEA
ISO
KEGG
SMPDB
SMP:00040 rno:00010 NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase IEA
ISO
KEGG
SMPDB
SMP:00040 rno:00010 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
JBrowse link
G Gapdh-ps118 Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 118 IEA KEGG rno:00010 NCBI chr18:63,896,780...63,898,072 JBrowse link
G Gapdhl10 glyceraldehyde-3-phosphate dehydrogenase like 10 IEA KEGG rno:00010 NCBI chr16:15,391,984...15,392,965
Ensembl chr16:28,796,572...28,797,885
JBrowse link
G Gapdhl3 glyceraldehyde-3-phosphate dehydrogenase like 3 IEA KEGG rno:00010 NCBI chr15:83,731,940...83,879,072 JBrowse link
G Gapdhl9 glyceraldehyde-3-phosphate dehydrogenase like 9 IEA KEGG rno:00010 NCBI chr 2:213,469,249...213,470,268 JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic IEA KEGG rno:00010 NCBI chr 1:95,106,516...95,125,918
Ensembl chr 1:95,106,518...95,121,055
JBrowse link
G Gck glucokinase TAS
IDA
IEA
KEGG
RGD
PMID:9540816 PMID:4273555 PMID:4353083 rno:00010, RGD:2302784, RGD:2302790, RGD:2302851 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949
JBrowse link
G Gpi glucose-6-phosphate isomerase IEA
ISO
KEGG
SMPDB
SMP:00040 rno:00010 NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261
JBrowse link
G Hk1 hexokinase 1 TAS
IDA
IEA
KEGG
RGD
PMID:9540816 PMID:4353083 rno:00010, RGD:2302784, RGD:2302851 NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814
JBrowse link
G Hk2 hexokinase 2 TAS
IEA
ISO
KEGG
SMPDB
RGD
PMID:9540816 SMP:00040 rno:00010, RGD:2302784 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
JBrowse link
G Hk3 hexokinase 3 TAS
IEA
KEGG
RGD
PMID:9540816 rno:00010, RGD:2302784 NCBI chr17:9,602,119...9,620,038
Ensembl chr17:9,605,016...9,620,037
JBrowse link
G Ldha lactate dehydrogenase A IEA KEGG rno:00010 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
JBrowse link
G Ldhal1 lactate dehydrogenase A like 1 IEA KEGG rno:00010 NCBI chr 8:38,621,351...38,622,975 JBrowse link
G Ldhal6b lactate dehydrogenase A-like 6B IEA KEGG rno:00010 NCBI chr 1:48,402,997...48,404,420
Ensembl chr 1:48,403,012...48,404,851
JBrowse link
G Ldhb lactate dehydrogenase B IEA KEGG rno:00010 NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408
JBrowse link
G Ldhc lactate dehydrogenase C IEA KEGG rno:00010 NCBI chr 1:106,522,140...106,539,649
Ensembl chr 1:106,522,236...106,542,802
JBrowse link
G Pank1 pantothenate kinase 1 ISO SMPDB SMP:00040 NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:241,741,083...241,807,824
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IEA KEGG rno:00010 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) IEA KEGG rno:00010 NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 IEA KEGG rno:00010 NCBI chr  X:38,509,158...38,522,986
Ensembl chr  X:38,509,084...38,522,536
JBrowse link
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 IEA KEGG rno:00010 NCBI chr 2:232,545,550...232,547,098
Ensembl chr 2:232,415,088...232,549,624
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta IEA KEGG rno:00010 NCBI chr15:19,182,789...19,188,731
Ensembl chr15:19,181,208...19,188,976
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 TAS RGD PMID:15170386 RGD:2302793 NCBI chr  X:22,936,038...22,989,691
Ensembl chr  X:22,937,494...22,989,704
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 TAS RGD PMID:15170386 RGD:2302793 NCBI chr13:44,683,499...44,727,135
Ensembl chr13:44,699,744...44,726,971
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 TAS RGD PMID:15170386 RGD:2302793 NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 TAS RGD PMID:15170386 RGD:2302793 NCBI chr 8:118,522,371...118,565,478
Ensembl chr 8:118,522,365...118,565,468
JBrowse link
G Pfkl phosphofructokinase, liver type TAS
IDA
IEA
KEGG
RGD
PMID:2931076 PMID:4273555 PMID:4353083 rno:00010, RGD:2302736, RGD:2302790, RGD:2302851 NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,663,955...10,685,966
JBrowse link
G Pfkm phosphofructokinase, muscle TAS
IEA
ISO
KEGG
SMPDB
RGD
PMID:2931076 SMP:00040 rno:00010, RGD:2302736 NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248
JBrowse link
G Pfkp phosphofructokinase, platelet TAS
IEA
KEGG
RGD
PMID:2931076 rno:00010, RGD:2302736 NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752
JBrowse link
G Pgam1 phosphoglycerate mutase 1 ISO
IEA
KEGG
SMPDB
RGD
PMID:18092946 SMP:00040 rno:00010, RGD:2302794 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203
JBrowse link
G Pgam2 phosphoglycerate mutase 2 ISO
IEA
KEGG
SMPDB
RGD
PMID:18092946 SMP:00040 rno:00010, RGD:2302794 NCBI chr14:84,895,763...84,897,874
Ensembl chr14:84,895,744...84,897,894
JBrowse link
G Pgk1 phosphoglycerate kinase 1 IDA
IMP
IEA
KEGG
RGD
PMID:6405813 PMID:3091090 rno:00010, RGD:2302859, RGD:2302860 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:75,336,687...75,352,959
JBrowse link
G Pgk1l1 phosphoglycerate kinase 1 like 1 IEA KEGG rno:00010 NCBI chr 2:44,487,980...44,489,330
Ensembl chr 2:44,488,018...44,489,235
JBrowse link
G Pgk2 phosphoglycerate kinase 2 IEA KEGG rno:00010 NCBI chr 9:27,976,913...27,978,479
Ensembl chr 9:27,973,459...28,079,866
JBrowse link
G Pgm1 phosphoglucomutase 1 IEA KEGG rno:00010 NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159
JBrowse link
G Pklr pyruvate kinase L/R IDA
IEA
ISO
KEGG
SMPDB
RGD
PMID:4273555 PMID:4353083 SMP:00040 rno:00010, RGD:2302790, RGD:2302851 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
JBrowse link
G Pkm pyruvate kinase M1/2 IDA RGD PMID:4273555 RGD:2302790 NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO SMPDB SMP:00040 NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467
JBrowse link
G Tpi1 triosephosphate isomerase 1 IEA
ISO
KEGG
SMPDB
SMP:00040 rno:00010 NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:159,301,562...159,305,413
JBrowse link
G Tpi1l2 triosephosphate isomerase 1 like 2 IEA KEGG rno:00010 NCBI chr17:27,307,380...28,230,998
Ensembl chr17:27,306,345...27,308,391
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    classic metabolic pathway 1853
      carbohydrate metabolic pathway 526
        glucose metabolic pathway 153
          glycolysis/gluconeogenesis pathway 81
            glycolysis pathway 72
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3864
      homeostasis pathway 1772
        organic chemical homeostasis pathway 767
          glucose homeostasis pathway 344
            glucose utilization pathway 121
              glucose oxidation pathway 100
                glycolysis pathway 72
paths to the root