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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal primitive streak formation
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Accession:MP:0002230 term browser browse the term
Definition:anomaly in the establishment of the midline ridge of embryonic epiblast that later develops into mesoderm and endoderm


show annotations for term's descendants           Sort by:
abnormal primitive streak formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor, type 1 IAGP MGI PMID:10226013 PMID:10479450 NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169 		JBrowse link
G Acvr1b activin A receptor, type 1B IAGP MGI PMID:16564040 NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565 		JBrowse link
G Amn amnionless IAGP MGI PMID:9851841 NCBI chr12:111,237,530...111,242,860
Ensembl chr12:111,237,529...111,242,860 		JBrowse link
G Bptf bromodomain PHD finger transcription factor IAGP MGI PMID:18794365 NCBI chr11:106,923,907...107,022,982
Ensembl chr11:106,923,907...107,022,953 		JBrowse link
G Brca1 breast cancer 1, early onset IAGP MGI PMID:9872327 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist IAGP MGI PMID:12431380 NCBI chr 4:82,799,988...82,803,388
Ensembl chr 4:82,799,988...82,803,385 		JBrowse link
G Cripto cripto, EGF-CFC family member IAGP MGI PMID:18268105 NCBI chr 9:110,768,676...110,775,226
Ensembl chr 9:110,768,671...110,775,226 		JBrowse link
G Ddx6 DEAD-box helicase 6 IAGP MGI PMID:36197846 NCBI chr 9:44,514,113...44,552,028
Ensembl chr 9:44,516,189...44,552,028 		JBrowse link
G Dhx9 DExH-box helicase 9 IAGP MGI PMID:9811865 NCBI chr 1:153,331,506...153,363,464
Ensembl chr 1:153,331,504...153,363,406 		JBrowse link
G Drap1 DR1 associated protein 1 IAGP MGI PMID:12471260 NCBI chr19:5,472,832...5,475,007
Ensembl chr19:5,472,833...5,475,007 		JBrowse link
G Foxa2 forkhead box A2 IAGP MGI PMID:8069909 PMID:11291865 NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889 		JBrowse link
G Furin furin, paired basic amino acid cleaving enzyme IAGP MGI PMID:12447384 NCBI chr 7:80,038,942...80,055,188
Ensembl chr 7:80,038,333...80,055,184 		JBrowse link
G Gdf1 growth differentiation factor 1 IAGP MGI PMID:16564040 PMID:17936261 NCBI chr 8:70,768,425...70,784,242
Ensembl chr 8:70,768,425...70,784,242
Ensembl chr 8:70,768,425...70,784,242 		JBrowse link
G Gdf3 growth differentiation factor 3 IAGP MGI PMID:16368929 PMID:17936261 NCBI chr 6:122,582,362...122,587,046
Ensembl chr 6:122,582,362...122,587,046 		JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha IAGP MGI PMID:7958910 NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830 		JBrowse link
G Ldb1 LIM domain binding 1 IAGP MGI PMID:12490556 NCBI chr19:46,019,963...46,036,584
Ensembl chr19:46,020,009...46,033,653 		JBrowse link
G Lefty1 left right determination factor 1 IAGP MGI PMID:12431380 NCBI chr 1:180,762,587...180,765,966
Ensembl chr 1:180,762,587...180,765,965 		JBrowse link
G Lhx1 LIM homeobox protein 1 IAGP MGI PMID:11291865 NCBI chr11:84,408,801...84,416,360
Ensembl chr11:84,409,110...84,416,361 		JBrowse link
G Lrp5 low density lipoprotein receptor-related protein 5 IAGP MGI PMID:15142971 NCBI chr19:3,634,825...3,736,574
Ensembl chr19:3,634,828...3,736,564 		JBrowse link
G Lrp6 low density lipoprotein receptor-related protein 6 IAGP MGI PMID:15142971 NCBI chr 6:134,423,439...134,543,876
Ensembl chr 6:134,423,439...134,543,928 		JBrowse link
G Mesp1 mesoderm posterior 1 IAGP MGI PMID:10887078 NCBI chr 7:79,441,989...79,443,338
Ensembl chr 7:79,441,989...79,443,536 		JBrowse link
G Mesp2 mesoderm posterior 2 IAGP MGI PMID:10887078 NCBI chr 7:79,460,475...79,463,179
Ensembl chr 7:79,460,475...79,463,187 		JBrowse link
G Nckap1 NCK-associated protein 1 IAGP MGI PMID:16831833 NCBI chr 2:80,330,856...80,411,526
Ensembl chr 2:80,330,856...80,411,724 		JBrowse link
G Nodal nodal growth differentiation factor IAGP MGI PMID:12471260 PMID:16950123 NCBI chr10:61,253,751...61,261,117
Ensembl chr10:61,253,751...61,261,117 		JBrowse link
G Nog noggin IAGP MGI PMID:20508035 NCBI chr11:89,191,464...89,193,385
Ensembl chr11:89,191,464...89,193,158 		JBrowse link
G Otx2 orthodenticle homeobox 2 IAGP MGI PMID:8565836 PMID:11291865 NCBI chr14:48,894,238...48,905,101
Ensembl chr14:48,895,134...48,911,276 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 IAGP MGI PMID:12447384 NCBI chr 7:65,511,884...65,700,134
Ensembl chr 7:65,511,482...65,700,134 		JBrowse link
G Rac1 Rac family small GTPase 1 IAGP MGI PMID:20689803 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rps6ka6 ribosomal protein S6 kinase polypeptide 6 IEA MGI NCBI chr  X:110,297,534...110,447,794
Ensembl chr  X:110,297,889...110,447,656 		JBrowse link
G Smad3 SMAD family member 3 IAGP MGI PMID:20508035 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G T brachyury, T-box transcription factor T IAGP MGI PMID:8293872 PMID:12140191 NCBI chr17:8,653,255...8,661,328
Ensembl chr17:8,653,255...8,661,328 		JBrowse link
G Tcf7l1 transcription factor 7 like 1 (T cell specific, HMG box) IAGP MGI PMID:14668413 NCBI chr 6:72,603,354...72,766,028
Ensembl chr 6:72,603,361...72,766,237 		JBrowse link
G Tlx2 T cell leukemia, homeobox 2 IAGP MGI PMID:9550720 NCBI chr 6:83,045,306...83,047,206
Ensembl chr 6:83,045,305...83,047,274 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 IAGP MGI PMID:17475776 NCBI chr14:76,082,771...76,085,743
Ensembl chr14:76,082,533...76,085,965 		JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 IAGP MGI PMID:35440748 NCBI chr  X:20,524,660...20,549,420
Ensembl chr  X:20,524,565...20,549,418 		JBrowse link
G Usp39 ubiquitin specific peptidase 39 IAGP MGI PMID:35440748 NCBI chr 6:72,295,749...72,322,190
Ensembl chr 6:72,295,661...72,322,167 		JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A IAGP MGI PMID:10021340 NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405 		JBrowse link
failure of primitive streak formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr8 ARP8 actin-related protein 8 IEA MGI NCBI chr14:29,700,294...29,717,409
Ensembl chr14:29,700,294...29,728,311 		JBrowse link
G Acvr1b activin A receptor, type 1B IAGP MGI PMID:9512518 NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565 		JBrowse link
G Ap2s1 adaptor-related protein complex 2, sigma 1 subunit IEA MGI NCBI chr 7:16,472,369...16,483,215
Ensembl chr 7:16,472,335...16,483,219 		JBrowse link
G Bcs1l BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone IEA MGI NCBI chr 1:74,627,448...74,631,602
Ensembl chr 1:74,627,448...74,631,602 		JBrowse link
G Bmp4 bone morphogenetic protein 4 IAGP MGI PMID:7657163 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor, type 1A IAGP MGI PMID:8543149 NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IAGP MGI PMID:10772805 NCBI chr 1:59,802,721...59,917,240
Ensembl chr 1:59,802,559...59,918,173 		JBrowse link
G Borcs6 BLOC-1 related complex subunit 6 IEA MGI NCBI chr11:68,950,601...68,952,402
Ensembl chr11:68,950,543...68,952,404 		JBrowse link
G Bptf bromodomain PHD finger transcription factor IAGP MGI PMID:18974875 NCBI chr11:106,923,907...107,022,982
Ensembl chr11:106,923,907...107,022,953 		JBrowse link
G Brca1 breast cancer 1, early onset IAGP MGI PMID:8674108 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Ccdc59 coiled-coil domain containing 59 IEA MGI NCBI chr10:105,677,340...105,683,371
Ensembl chr10:105,676,928...105,683,694 		JBrowse link
G Cenpo centromere protein O IEA MGI NCBI chr12:4,243,548...4,284,255
Ensembl chr12:4,246,004...4,284,294 		JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 IAGP MGI PMID:15367660 NCBI chr14:52,435,608...52,495,499
Ensembl chr14:52,435,608...52,495,237 		JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit IEA MGI NCBI chr 9:65,201,533...65,237,940
Ensembl chr 9:65,201,542...65,237,940 		JBrowse link
G Cripto cripto, EGF-CFC family member IAGP MGI PMID:9790191 NCBI chr 9:110,768,676...110,775,226
Ensembl chr 9:110,768,671...110,775,226 		JBrowse link
G Cul4b cullin 4B IAGP MGI PMID:22453236 NCBI chr  X:37,620,493...37,665,073
Ensembl chr  X:37,622,151...37,665,073 		JBrowse link
G Ddx59 DEAD box helicase 59 IEA MGI NCBI chr 1:136,343,009...136,384,019
Ensembl chr 1:136,343,009...136,367,896 		JBrowse link
G Dolk dolichol kinase IEA MGI NCBI chr 2:30,174,241...30,176,366
Ensembl chr 2:30,174,243...30,176,346 		JBrowse link
G Dpy30 dpy-30, histone methyltransferase complex regulatory subunit IAGP MGI PMID:25805847 NCBI chr17:74,606,469...74,630,939
Ensembl chr17:74,606,469...74,630,939 		JBrowse link
G Elof1 ELF1 homolog, elongation factor 1 IAGP MGI PMID:31276560 NCBI chr 9:22,024,282...22,028,491
Ensembl chr 9:22,024,285...22,028,468 		JBrowse link
G Eomes eomesodermin IAGP MGI PMID:18171685 NCBI chr 9:118,307,259...118,315,176
Ensembl chr 9:118,307,280...118,315,200 		JBrowse link
G Exosc1 exosome component 1 IAGP MGI PMID:37940010 NCBI chr19:41,911,417...41,921,836
Ensembl chr19:41,910,731...41,921,862 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 IAGP MGI PMID:10926768 NCBI chr15:52,931,657...53,209,579
Ensembl chr15:52,927,434...53,209,555 		JBrowse link
G Ext2 exostosin glycosyltransferase 2 IAGP MGI PMID:16236767 NCBI chr 2:93,525,978...93,652,913
Ensembl chr 2:93,491,373...93,652,913 		JBrowse link
G Fastkd5 FAST kinase domains 5 IEA MGI NCBI chr 2:130,455,766...130,471,922
Ensembl chr 2:130,455,760...130,471,947 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 IAGP MGI PMID:8001822 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734 		JBrowse link
G Foxd3 forkhead box D3 IAGP MGI PMID:12381664 NCBI chr 4:99,544,536...99,546,908
Ensembl chr 4:99,544,536...99,546,859 		JBrowse link
G Glrx3 glutaredoxin 3 IEA MGI NCBI chr 7:137,039,302...137,071,360
Ensembl chr 7:137,039,343...137,070,323 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:10477299 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hlcs holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) IEA MGI NCBI chr16:93,930,054...94,116,098
Ensembl chr16:93,929,741...94,114,430 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 IAGP MGI PMID:17634284 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Ipo11 importin 11 IEA MGI NCBI chr13:106,930,947...107,073,466
Ensembl chr13:106,930,947...107,073,466 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 IEA MGI NCBI chr13:59,903,229...59,917,603
Ensembl chr13:59,903,223...59,917,624 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 IAGP MGI PMID:16815997 NCBI chr 4:123,243,386...123,581,594
Ensembl chr 4:123,243,426...123,581,331 		JBrowse link
G Mars2 methionine-tRNA synthetase 2 (mitochondrial) IEA MGI NCBI chr 1:55,276,336...55,279,217
Ensembl chr 1:55,276,336...55,287,629 		JBrowse link
G Mesd mesoderm development LRP chaperone IAGP MGI PMID:21337463 NCBI chr 7:83,533,074...83,549,519
Ensembl chr 7:83,533,674...83,550,740 		JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 IEA MGI NCBI chr11:58,060,850...58,070,406
Ensembl chr11:58,062,487...58,070,391 		JBrowse link
G Mrpl3 mitochondrial ribosomal protein L3 IEA MGI NCBI chr 9:104,930,394...104,954,665
Ensembl chr 9:104,930,438...104,957,087 		JBrowse link
G Mrpl44 mitochondrial ribosomal protein L44 IEA MGI NCBI chr 1:79,753,735...79,759,162
Ensembl chr 1:79,753,735...79,759,162 		JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C IEA MGI NCBI chr 5:100,946,625...100,952,333
Ensembl chr 5:100,946,493...100,952,337 		JBrowse link
G Mrps22 mitochondrial ribosomal protein S22 IEA MGI NCBI chr 9:98,470,783...98,483,732
Ensembl chr 9:98,470,783...98,483,713 		JBrowse link
G Mrps25 mitochondrial ribosomal protein S25 IEA MGI NCBI chr 6:92,146,493...92,161,004
Ensembl chr 6:92,146,506...92,161,014 		JBrowse link
G Myl1 myosin, light polypeptide 1 IAGP MGI PMID:11884037 NCBI chr 1:66,963,454...66,987,091
Ensembl chr 1:66,963,454...66,984,563 		JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 (putative) IAGP MGI PMID:20606008 NCBI chr16:87,151,073...87,165,537
Ensembl chr16:87,151,073...87,165,630 		JBrowse link
G Nars2 asparaginyl-tRNA synthetase 2 (mitochondrial)(putative) IEA MGI NCBI chr 7:96,600,698...96,725,606
Ensembl chr 7:96,600,712...96,713,965 		JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 IEA MGI NCBI chr 6:126,798,826...126,826,107
Ensembl chr 6:126,798,684...126,826,099 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 IEA MGI NCBI chr19:3,958,863...3,962,774
Ensembl chr19:3,958,863...3,962,774 		JBrowse link
G Nfe2l1 nuclear factor, erythroid derived 2,-like 1 IAGP MGI PMID:9087432 NCBI chr11:96,708,239...96,720,810
Ensembl chr11:96,708,240...96,720,794 		JBrowse link
G Nodal nodal growth differentiation factor IAGP MGI PMID:7924997 PMID:18171685 NCBI chr10:61,253,751...61,261,117
Ensembl chr10:61,253,751...61,261,117 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 IAGP MGI PMID:21283715 NCBI chr18:30,390,441...30,481,179
Ensembl chr18:30,405,800...30,481,179 		JBrowse link
G Pknox1 Pbx/knotted 1 homeobox IAGP MGI PMID:20826531 NCBI chr17:31,783,697...31,826,665
Ensembl chr17:31,783,708...31,826,667 		JBrowse link
G Pnn pinin IAGP MGI PMID:17654715 NCBI chr12:59,113,705...59,120,803
Ensembl chr12:59,113,670...59,120,784 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 IAGP MGI PMID:19706528 NCBI chr15:93,396,992...93,494,147
Ensembl chr15:93,396,995...93,493,772 		JBrowse link
G Rab10 RAB10, member RAS oncogene family IAGP MGI PMID:25860786 NCBI chr12:3,297,428...3,359,969
Ensembl chr12:3,297,428...3,359,969 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family IEA MGI NCBI chr 9:64,622,582...64,645,038
Ensembl chr 9:64,622,581...64,645,040 		JBrowse link
G Scx scleraxis scleraxis bHLH transcription factor IAGP MGI PMID:10477299 NCBI chr15:76,341,594...76,343,668
Ensembl chr15:76,341,652...76,343,658 		JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 IEA MGI NCBI chr19:10,477,876...10,502,573
Ensembl chr19:10,477,898...10,503,506 		JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 IEA MGI NCBI chr11:87,000,087...87,013,800
Ensembl chr11:87,000,060...87,015,461 		JBrowse link
G Smad2 SMAD family member 2 IAGP MGI PMID:9529255 PMID:9655392 PMID:9689088 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034 		JBrowse link
G Smad4 SMAD family member 4 IAGP MGI PMID:9420335 PMID:9520423 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A IEA MGI NCBI chr12:54,692,159...54,703,357
Ensembl chr12:54,692,177...54,703,358 		JBrowse link
G Srf serum response factor IAGP MGI PMID:9799237 NCBI chr17:46,857,764...46,869,194
Ensembl chr17:46,859,255...46,867,101 		JBrowse link
G Tfap2c transcription factor AP-2, gamma IAGP MGI PMID:12015300 NCBI chr 2:172,387,599...172,400,542
Ensembl chr 2:172,391,513...172,400,542 		JBrowse link
G Timm22 translocase of inner mitochondrial membrane 22 IEA MGI NCBI chr11:76,297,751...76,307,139
Ensembl chr11:76,297,778...76,307,118 		JBrowse link
G Tpk1 thiamine pyrophosphokinase IEA MGI NCBI chr 6:43,316,510...43,644,726
Ensembl chr 6:43,321,935...43,643,212 		JBrowse link
G Trim33 tripartite motif-containing 33 IAGP MGI PMID:20573697 NCBI chr 3:103,186,609...103,266,086
Ensembl chr 3:103,186,609...103,266,091 		JBrowse link
G Trim59 tripartite motif-containing 59 IAGP MGI PMID:29467473 NCBI chr 3:68,942,625...68,952,075
Ensembl chr 3:68,942,621...68,952,088 		JBrowse link
G Tsg101 tumor susceptibility gene 101 IAGP MGI PMID:11172041 NCBI chr 7:46,538,693...46,569,716
Ensembl chr 7:46,538,697...46,569,717 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IAGP MGI PMID:17697936 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 IAGP MGI PMID:25127365 NCBI chr 4:148,518,952...148,529,217
Ensembl chr 4:148,518,952...148,529,228 		JBrowse link
G Usp39 ubiquitin specific peptidase 39 IAGP MGI PMID:35440748 NCBI chr 6:72,295,749...72,322,190
Ensembl chr 6:72,295,661...72,322,167 		JBrowse link
G Washc4 WASH complex subunit 4 IEA MGI NCBI chr10:83,379,073...83,432,350
Ensembl chr10:83,379,616...83,432,337 		JBrowse link
G Wls wntless WNT ligand secretion mediator IAGP MGI PMID:19841259 PMID:20614471 PMID:21246653 NCBI chr 3:159,545,287...159,644,302
Ensembl chr 3:159,545,309...159,644,300 		JBrowse link
G Wnt3 wingless-type MMTV integration site family, member 3 IAGP MGI PMID:10431240 NCBI chr11:103,665,000...103,708,854
Ensembl chr11:103,664,976...103,708,783 		JBrowse link
G Ylpm1 YLP motif containing 1 IEA MGI NCBI chr12:85,042,977...85,130,501
Ensembl chr12:85,043,095...85,117,289 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16762
    embryo phenotype 2417
      abnormal embryo morphology 1842
        abnormal embryonic tissue morphology 1264
          abnormal primitive streak morphology 192
            abnormal primitive streak formation 106
              failure of primitive streak formation 75
paths to the root