Eomes (eomesodermin) - Rat Genome Database
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Gene: Eomes (eomesodermin) Mus musculus
Analyze
Symbol: Eomes
Name: eomesodermin
RGD ID: 1552408
MGI Page MGI
Description: Exhibits RNA polymerase II activating transcription factor binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including animal organ development; formation of primary germ layer; and regulation of transcription, DNA-templated. Localizes to nuclear chromatin. Is expressed in several structures, including brain; early conceptus; eye; gonad; and limb. Orthologous to human EOMES (eomesodermin); PARTICIPATES IN interleukin-12 signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C77258; eomesodermin homolog; T-box brain protein 2; T-brain-2; Tbr; TBR-2; Tbr2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,307,254 - 118,315,200 (+)NCBIGRCm39mm39
GRCm389118,478,186 - 118,486,132 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9118,478,212 - 118,486,132 (+)EnsemblGRCm38mm10GRCm38
MGSCv379118,387,307 - 118,395,250 (+)NCBIGRCm37mm9NCBIm37
MGSCv369118,327,042 - 118,334,830 (+)NCBImm8
Celera9118,948,428 - 118,956,371 (+)NCBICelera
Cytogenetic Map9F3NCBI
cM Map970.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IDA)
nucleus  (IDA)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adipose tissue amount  (IEA)
abnormal amniotic cavity morphology  (IAGP)
abnormal anterior primitive streak morphology  (IAGP)
abnormal anterior visceral endoderm cell migration  (IAGP)
abnormal axon guidance  (IAGP)
abnormal bone mineralization  (IEA)
abnormal CD8-positive, alpha-beta T cell differentiation  (IAGP)
abnormal dentate gyrus morphology  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal egg cylinder morphology  (IAGP)
abnormal embryonic epiblast morphology  (IAGP)
abnormal endoderm development  (IAGP)
abnormal germ layer development  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal interleukin level  (IAGP)
abnormal lean body mass  (IEA)
abnormal left-right axis patterning  (IAGP)
abnormal leukocyte migration  (IAGP)
abnormal leukocyte physiology  (IAGP)
abnormal neuron apoptosis  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal NK cell differentiation  (IAGP)
abnormal notochord morphology  (IAGP)
abnormal olfactory bulb morphology  (IAGP)
abnormal optic nerve morphology  (IAGP)
abnormal primitive node morphology  (IAGP)
abnormal primitive streak elongation  (IAGP)
abnormal primitive streak morphology  (IAGP)
abnormal retinal ganglion cell morphology  (IAGP)
abnormal rostral-caudal patterning of the somites  (IAGP)
abnormal T cell morphology  (IAGP)
abnormal trophoblast layer morphology  (IAGP)
abnormal visceral endoderm morphology  (IAGP)
absent anterior commissure  (IAGP)
absent mesoderm  (IAGP)
absent primitive node  (IAGP)
absent trophectoderm  (IAGP)
absent trophoblast giant cells  (IAGP)
decreased brain size  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating creatinine level  (IEA)
decreased grip strength  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased lean body mass  (IEA)
decreased memory T cell number  (IAGP)
decreased NK cell number  (IAGP)
decreased NK T cell number  (IAGP)
decreased red blood cell distribution width  (IEA)
decreased retinal ganglion cell number  (IAGP)
disorganized embryonic tissue  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality before implantation, complete penetrance  (IAGP)
embryonic lethality between implantation and placentation  (IAGP)
embryonic lethality between implantation and placentation, complete penetrance  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality prior to organogenesis  (IEA)
embryonic lethality prior to tooth bud stage  (IEA)
embryonic-extraembryonic boundary constriction  (IAGP)
enlarged floor plate  (IAGP)
failure of embryo implantation  (IAGP)
failure of primitive streak formation  (IAGP)
failure to gastrulate  (IAGP)
hyperactivity  (IAGP)
increased aggression towards humans  (IAGP)
increased aggression towards mice  (IAGP)
increased interleukin-17 secretion  (IAGP)
increased interleukin-4 secretion  (IAGP)
increased neutrophil cell number  (IAGP)
increased retinal apoptosis  (IAGP)
increased somite number  (IAGP)
increased susceptibility to Riboviria infection  (IAGP)
increased total body fat amount  (IEA)
increased tumor incidence  (IAGP)
no abnormal phenotype detected  (IAGP)
prenatal lethality  (IAGP)
preweaning lethality, complete penetrance  (IEA)
rostral body truncation  (IAGP)
rostral-caudal axis duplication  (IAGP)
small olfactory bulb  (IAGP)
thin cerebral cortex  (IAGP)
thin retinal ganglion layer  (IAGP)
References

Additional References at PubMed
PMID:2137249   PMID:8889548   PMID:9503012   PMID:10330500   PMID:10330501   PMID:10349636   PMID:10444332   PMID:10473127   PMID:10804179   PMID:11042159   PMID:11076861   PMID:11124115  
PMID:11171400   PMID:11217851   PMID:11239428   PMID:11412024   PMID:11566864   PMID:11739261   PMID:12015300   PMID:12091315   PMID:12118260   PMID:12128215   PMID:12381664   PMID:12447384  
PMID:12477932   PMID:12748966   PMID:12764040   PMID:12925581   PMID:14511481   PMID:14605368   PMID:14681479   PMID:15142957   PMID:15198985   PMID:15215210   PMID:15302604   PMID:15469968  
PMID:15618518   PMID:15632069   PMID:15634788   PMID:15788452   PMID:15829518   PMID:15858069   PMID:15870281   PMID:15880683   PMID:16141072   PMID:16141073   PMID:16204645   PMID:16239343  
PMID:16273099   PMID:16325584   PMID:16397896   PMID:16540585   PMID:16556918   PMID:16602821   PMID:16621079   PMID:16631155   PMID:16887818   PMID:16892058   PMID:16951332   PMID:16957075  
PMID:16957084   PMID:16979618   PMID:17075876   PMID:17158062   PMID:17182866   PMID:17312115   PMID:17417802   PMID:17470284   PMID:17634284   PMID:17656621   PMID:17699604   PMID:17706960  
PMID:17913785   PMID:17916349   PMID:17942732   PMID:17953485   PMID:17959791   PMID:18028899   PMID:18033766   PMID:18061570   PMID:18065723   PMID:18067887   PMID:18077589   PMID:18083014  
PMID:18084280   PMID:18163532   PMID:18165280   PMID:18171685   PMID:18194653   PMID:18205207   PMID:18287559   PMID:18356246   PMID:18385329   PMID:18460603   PMID:18469343   PMID:18521945  
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PMID:18940587   PMID:18940588   PMID:18997111   PMID:18997113   PMID:19000783   PMID:19030180   PMID:19050290   PMID:19056494   PMID:19056886   PMID:19059340   PMID:19103804   PMID:19136970  
PMID:19149881   PMID:19150975   PMID:19153222   PMID:19168665   PMID:19192266   PMID:19224637   PMID:19234065   PMID:19386638   PMID:19403657   PMID:19409883   PMID:19433082   PMID:19435790  
PMID:19439493   PMID:19521500   PMID:19535581   PMID:19564597   PMID:19571125   PMID:19607792   PMID:19641124   PMID:19666823   PMID:19668217   PMID:19686682   PMID:19709628   PMID:19726493  
PMID:19749747   PMID:19796622   PMID:19805316   PMID:19806666   PMID:19830823   PMID:19838179   PMID:19879845   PMID:19883498   PMID:19923290   PMID:19943849   PMID:19948250   PMID:20007774  
PMID:20014105   PMID:20059953   PMID:20060330   PMID:20081188   PMID:20081193   PMID:20103535   PMID:20145110   PMID:20176728   PMID:20181597   PMID:20215343   PMID:20237272   PMID:20348416  
PMID:20364144   PMID:20399120   PMID:20399730   PMID:20410112   PMID:20431123   PMID:20460369   PMID:20498066   PMID:20506362   PMID:20510365   PMID:20525896   PMID:20573697   PMID:20610746  
PMID:20615956   PMID:20619750   PMID:20637190   PMID:20668538   PMID:20685850   PMID:20685999   PMID:20696378   PMID:20702706   PMID:20708584   PMID:20713522   PMID:20713880   PMID:20729831  
PMID:20798045   PMID:20808958   PMID:20811503   PMID:20823249   PMID:20825492   PMID:20876643   PMID:20935171   PMID:20935204   PMID:20935640   PMID:20969844   PMID:20969845   PMID:21076068  
PMID:21220025   PMID:21245162   PMID:21256837   PMID:21349854   PMID:21368052   PMID:21383242   PMID:21431469   PMID:21440680   PMID:21445260   PMID:21466690   PMID:21471969   PMID:21485009  
PMID:21490064   PMID:21491541   PMID:21509901   PMID:21525285   PMID:21600798   PMID:21652654   PMID:21666133   PMID:21673655   PMID:21677750   PMID:21681860   PMID:21697387   PMID:21710638  
PMID:21731673   PMID:21734301   PMID:21763783   PMID:21803034   PMID:21806820   PMID:21822279   PMID:21826226   PMID:21862448   PMID:21864333   PMID:21873635   PMID:21880986   PMID:21887788  
PMID:21896659   PMID:21900571   PMID:21940433   PMID:21953618   PMID:21965613   PMID:21966449   PMID:21976703   PMID:21991391   PMID:22017987   PMID:22028030   PMID:22031906   PMID:22032925  
PMID:22056141   PMID:22056358   PMID:22069190   PMID:22077982   PMID:22078635   PMID:22090492   PMID:22090513   PMID:22095214   PMID:22095278   PMID:22116031   PMID:22118525   PMID:22138645  
PMID:22147266   PMID:22151329   PMID:22160720   PMID:22164283   PMID:22206758   PMID:22223678   PMID:22228756   PMID:22232070   PMID:22261438   PMID:22266795   PMID:22334647   PMID:22351047  
PMID:22365545   PMID:22370000   PMID:22402664   PMID:22405202   PMID:22425747   PMID:22461901   PMID:22479190   PMID:22516202   PMID:22522171   PMID:22522401   PMID:22529382   PMID:22532528  
PMID:22542597   PMID:22544698   PMID:22553033   PMID:22573614   PMID:22586092   PMID:22588081   PMID:22645310   PMID:22649246   PMID:22669107   PMID:22705452   PMID:22718343   PMID:22723706  
PMID:22726835   PMID:22745484   PMID:22817342   PMID:22879516   PMID:22892427   PMID:22906231   PMID:22912414   PMID:22923088   PMID:22935140   PMID:22951639   PMID:22956844   PMID:22956851  
PMID:22981537   PMID:22991445   PMID:22992956   PMID:23011795   PMID:23018676   PMID:23042739   PMID:23147502   PMID:23160044   PMID:23175820   PMID:23180754   PMID:23180766   PMID:23197535  
PMID:23259060   PMID:23283338   PMID:23293287   PMID:23300826   PMID:23303943   PMID:23349620   PMID:23353076   PMID:23355737   PMID:23382203   PMID:23404109   PMID:23431145   PMID:23434913  
PMID:23447624   PMID:23454273   PMID:23459943   PMID:23469192   PMID:23472160   PMID:23473982   PMID:23499385   PMID:23547098   PMID:23552073   PMID:23569256   PMID:23578932   PMID:23584530  
PMID:23595735   PMID:23615279   PMID:23622239   PMID:23623502   PMID:23633963   PMID:23636056   PMID:23637172   PMID:23643363   PMID:23643936   PMID:23651855   PMID:23658188   PMID:23680462  
PMID:23699523   PMID:23727838   PMID:23749646   PMID:23751362   PMID:23760955   PMID:23765158   PMID:23776078   PMID:23788624   PMID:23817546   PMID:23863479   PMID:23895693   PMID:23897762  
PMID:23934214   PMID:23968833   PMID:23972596   PMID:24006458   PMID:24013503   PMID:24038449   PMID:24056717   PMID:24115331   PMID:24124161   PMID:24127404   PMID:24146773   PMID:24165879  
PMID:24173802   PMID:24192035   PMID:24194600   PMID:24238339   PMID:24260314   PMID:24301314   PMID:24301385   PMID:24381249   PMID:24448552   PMID:24453338   PMID:24483844   PMID:24489718  
PMID:24516120   PMID:24532575   PMID:24550175   PMID:24553927   PMID:24586484   PMID:24595293   PMID:24610119   PMID:24633704   PMID:24663216   PMID:24695699   PMID:24698271   PMID:24726360  
PMID:24733890   PMID:24741035   PMID:24741061   PMID:24771490   PMID:24792116   PMID:24803655   PMID:24823810   PMID:24832538   PMID:24835466   PMID:24839873   PMID:24857653   PMID:24859200  
PMID:24875059   PMID:24926615   PMID:24927931   PMID:24931612   PMID:24952961   PMID:24953933   PMID:24990151   PMID:25070536   PMID:25100583   PMID:25129370   PMID:25148024   PMID:25157170  
PMID:25182747   PMID:25186760   PMID:25198012   PMID:25207963   PMID:25209290   PMID:25228773   PMID:25249464   PMID:25253855   PMID:25273085   PMID:25282615   PMID:25331604   PMID:25336744  
PMID:25340657   PMID:25344561   PMID:25395668   PMID:25402856   PMID:25419850   PMID:25425146   PMID:25446528   PMID:25446535   PMID:25452572   PMID:25461193   PMID:25480914   PMID:25501893  
PMID:25521379   PMID:25535838   PMID:25556659   PMID:25556700   PMID:25609618   PMID:25641781   PMID:25698753   PMID:25721503   PMID:25757017   PMID:25775587   PMID:25794677   PMID:25804738  
PMID:25805847   PMID:25871744   PMID:25916825   PMID:25922525   PMID:25926459   PMID:25934499   PMID:25948253   PMID:25953241   PMID:25971728   PMID:25972180   PMID:25978062   PMID:25999820  
PMID:26030886   PMID:26033091   PMID:26067405   PMID:26124079   PMID:26158450   PMID:26182416   PMID:26203155   PMID:26206133   PMID:26209645   PMID:26220976   PMID:26238476   PMID:26269635  
PMID:26383973   PMID:26387942   PMID:26390156   PMID:26400936   PMID:26410627   PMID:26415720   PMID:26424889   PMID:26426795   PMID:26431380   PMID:26436530   PMID:26453746   PMID:26461455  
PMID:26494787   PMID:26509897   PMID:26511769   PMID:26579598   PMID:26584622   PMID:26586574   PMID:26651292   PMID:26657772   PMID:26671461   PMID:26694968   PMID:26701169   PMID:26714260  
PMID:26728556   PMID:26733533   PMID:26740489   PMID:26745185   PMID:26748089   PMID:26749212   PMID:26758805   PMID:26764350   PMID:26792802   PMID:26795843   PMID:26802325   PMID:26814967  
PMID:26830346   PMID:26856890   PMID:26903504   PMID:26921468   PMID:26939553   PMID:26961948   PMID:27005988   PMID:27037025   PMID:27067865   PMID:27111087   PMID:27117402   PMID:27142930  
PMID:27144456   PMID:27156386   PMID:27183623   PMID:27210758   PMID:27214567   PMID:27217206   PMID:27256596   PMID:27282384   PMID:27307230   PMID:27320921   PMID:27385014   PMID:27390776  
PMID:27445154   PMID:27452274   PMID:27476503   PMID:27496734   PMID:27504805   PMID:27510895   PMID:27562601   PMID:27565344   PMID:27581449   PMID:27586544   PMID:27599295   PMID:27600842  
PMID:27618312   PMID:27620979   PMID:27626380   PMID:27664421   PMID:27705792   PMID:27707753   PMID:27742544   PMID:27760115   PMID:27760310   PMID:27780844   PMID:27789627   PMID:27791111  
PMID:27798144   PMID:27798843   PMID:27806305   PMID:27845622   PMID:27848932   PMID:27871306   PMID:27965054   PMID:27965439   PMID:27974163   PMID:27982126   PMID:27993979   PMID:27993981  
PMID:28041877   PMID:28049832   PMID:28069738   PMID:28123024   PMID:28174238   PMID:28232627   PMID:28272472   PMID:28276603   PMID:28288114   PMID:28299779   PMID:28322231   PMID:28386934  
PMID:28401892   PMID:28450263   PMID:28462915   PMID:28467430   PMID:28475893   PMID:28482867   PMID:28494873   PMID:28506990   PMID:28514662   PMID:28550044   PMID:28552558   PMID:28584103  
PMID:28595361   PMID:28619992   PMID:28646547   PMID:28655839   PMID:28663132   PMID:28671691   PMID:28674667   PMID:28698286   PMID:28728023   PMID:28737488   PMID:28738016   PMID:28759001  
PMID:28768199   PMID:28781964   PMID:28790015   PMID:28790189   PMID:28794184   PMID:28805812   PMID:28808228   PMID:28814327   PMID:28816361   PMID:28839193   PMID:28874785   PMID:28892064  
PMID:28924369   PMID:28935707   PMID:28939666   PMID:28965759   PMID:28981589   PMID:28994651   PMID:29021239   PMID:29045729   PMID:29053761   PMID:29056343   PMID:29078390   PMID:29082311  
PMID:29086765   PMID:29088697   PMID:29132503   PMID:29168693   PMID:29180410   PMID:29241535   PMID:29271784   PMID:29294103   PMID:29305158   PMID:29311744   PMID:29317485   PMID:29335608  
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PMID:30186101   PMID:30201687   PMID:30208054   PMID:30217810   PMID:30224493   PMID:30260951   PMID:30266827   PMID:30304535   PMID:30329130   PMID:30332643   PMID:30344048   PMID:30361413  
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PMID:30635555   PMID:30659230   PMID:30668728   PMID:30677129   PMID:30692224   PMID:30709655   PMID:30796806   PMID:30842446   PMID:30864157   PMID:30894800   PMID:30914320   PMID:31018127  
PMID:31043608   PMID:31044175   PMID:31064784   PMID:31080058   PMID:31086189   PMID:31097699   PMID:31149899   PMID:31175212   PMID:31197172   PMID:31202705   PMID:31255486   PMID:31260508  
PMID:31273213   PMID:31277925   PMID:31315048   PMID:31318893   PMID:31319858   PMID:31340148   PMID:31371378   PMID:31386652   PMID:31393266   PMID:31396962   PMID:31399471   PMID:31415124  
PMID:31421080   PMID:31462248   PMID:31477701   PMID:31488566   PMID:31515109   PMID:31570595   PMID:31655624   PMID:31665628   PMID:31680852   PMID:31699896   PMID:31712428   PMID:31729356  
PMID:31736464   PMID:31792383   PMID:31794381   PMID:31794431   PMID:31794640   PMID:31810881   PMID:31816041   PMID:31816056   PMID:31845734   PMID:31911949   PMID:31914388   PMID:31919497  
PMID:32001437   PMID:32008040   PMID:32024956   PMID:32037591   PMID:32041791   PMID:32049024   PMID:32094111   PMID:32097653   PMID:32098764   PMID:32103003   PMID:32103006   PMID:32115408  
PMID:32170161   PMID:32182234   PMID:32186707   PMID:32234482   PMID:32238932   PMID:32242005   PMID:32245946   PMID:32321712   PMID:32404061   PMID:32415109   PMID:32439762   PMID:32492428  
PMID:32493987   PMID:32499648   PMID:32541003   PMID:32737167   PMID:32817053   PMID:32991634  


Genomics

Comparative Map Data
Eomes
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,307,254 - 118,315,200 (+)NCBIGRCm39mm39
GRCm389118,478,186 - 118,486,132 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9118,478,212 - 118,486,132 (+)EnsemblGRCm38mm10GRCm38
MGSCv379118,387,307 - 118,395,250 (+)NCBIGRCm37mm9NCBIm37
MGSCv369118,327,042 - 118,334,830 (+)NCBImm8
Celera9118,948,428 - 118,956,371 (+)NCBICelera
Cytogenetic Map9F3NCBI
cM Map970.21NCBI
EOMES
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl327,715,949 - 27,722,711 (-)EnsemblGRCh38hg38GRCh38
GRCh38327,715,953 - 27,722,713 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37327,757,440 - 27,764,206 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36327,732,872 - 27,738,789 (-)NCBINCBI36hg18NCBI36
Build 34327,732,890 - 27,738,789NCBI
Celera327,694,279 - 27,700,196 (-)NCBI
Cytogenetic Map3p24.1NCBI
HuRef327,699,819 - 27,706,575 (-)NCBIHuRef
CHM1_1327,707,433 - 27,714,192 (-)NCBICHM1_1
Eomes
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08127,144,367 - 127,152,618 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8127,144,903 - 127,151,493 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08126,369,713 - 126,375,233 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48123,376,689 - 123,383,451 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18123,398,873 - 123,402,528 (+)NCBI
Celera8117,369,438 - 117,374,985 (+)NCBICelera
Cytogenetic Map8q32NCBI
Eomes
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543019,281,602 - 19,286,867 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543019,280,460 - 19,287,060 (-)NCBIChiLan1.0ChiLan1.0
EOMES
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1327,923,970 - 27,930,687 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl327,925,086 - 27,930,274 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0327,601,829 - 27,608,701 (-)NCBIMhudiblu_PPA_v0panPan3
EOMES
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2316,506,032 - 16,511,527 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12316,476,498 - 16,512,406 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Eomes
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647318,825,969 - 18,833,179 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EOMES
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1314,210,083 - 14,215,797 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11314,209,590 - 14,216,184 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21315,846,197 - 15,852,753 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EOMES
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11572,257,626 - 72,264,563 (-)NCBI
Eomes
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247885,550,569 - 5,557,342 (-)NCBI

Position Markers
Eomes  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv379118,390,426 - 118,391,205UniSTSGRCm37
Celera9118,951,547 - 118,952,326UniSTS
Cytogenetic Map9F3UniSTS
cM Map967.0UniSTS
cM Map967.0UniSTS
UniSTS:236277  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389118,485,323 - 118,485,549UniSTSGRCm38
MGSCv379118,394,441 - 118,394,667UniSTSGRCm37
Celera9118,955,562 - 118,955,788UniSTS
Cytogenetic Map9F3UniSTS
cM Map967.0UniSTS
RH126131  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389118,485,865 - 118,486,066UniSTSGRCm38
MGSCv379118,394,983 - 118,395,184UniSTSGRCm37
Celera9118,956,104 - 118,956,305UniSTS
Cytogenetic Map9F3UniSTS
cM Map967.0UniSTS
Whitehead/MRC_RH91163.94UniSTS
Eomes  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9F3UniSTS
Eomes  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9F3UniSTS
Eomes  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389118,481,308 - 118,482,087UniSTSGRCm38
MGSCv379118,390,426 - 118,391,205UniSTSGRCm37
Celera9118,951,547 - 118,952,326UniSTS
Cytogenetic Map9F3UniSTS
Eomes  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9F3UniSTS
cM Map967.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse
13515058Adip20d_madiposity 20d (mouse)9108915010118915010Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:621
Count of miRNA genes:372
Interacting mature miRNAs:428
Transcripts:ENSMUST00000035020, ENSMUST00000111763, ENSMUST00000150633
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000035020   ⟹   ENSMUSP00000035020
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9118,478,344 - 118,486,132 (+)Ensembl
RefSeq Acc Id: ENSMUST00000111763   ⟹   ENSMUSP00000107393
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9118,478,212 - 118,485,366 (+)Ensembl
RefSeq Acc Id: ENSMUST00000150633   ⟹   ENSMUSP00000118079
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9118,478,861 - 118,482,757 (+)Ensembl
RefSeq Acc Id: NM_001164789   ⟹   NP_001158261
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,307,257 - 118,315,200 (+)NCBI
GRCm389118,478,189 - 118,486,132 (+)NCBI
MGSCv379118,387,307 - 118,395,250 (+)RGD
Celera9118,948,428 - 118,956,371 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010136   ⟹   NP_034266
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,307,257 - 118,315,200 (+)NCBI
GRCm389118,478,189 - 118,486,132 (+)NCBI
MGSCv379118,387,307 - 118,395,250 (+)RGD
Celera9118,948,428 - 118,956,371 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006511940   ⟹   XP_006512003
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399118,307,254 - 118,315,191 (+)NCBI
GRCm389118,478,186 - 118,486,123 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034266   ⟸   NM_010136
- Peptide Label: isoform 1
- UniProtKB: O54839 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001158261   ⟸   NM_001164789
- Peptide Label: isoform 2
- UniProtKB: O54839 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512003   ⟸   XM_006511940
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000118079   ⟸   ENSMUST00000150633
RefSeq Acc Id: ENSMUSP00000107393   ⟸   ENSMUST00000111763
RefSeq Acc Id: ENSMUSP00000035020   ⟸   ENSMUST00000035020
Protein Domains
T-box_assoc

Promoters
RGD ID:6844502
Promoter ID:MM_KWN:59091
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   Lung
Transcripts:NM_001164789,   OTTMUST00000049812,   UC009RZO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369118,387,596 - 118,388,387 (+)MPROMDB
RGD ID:8671162
Promoter ID:EPDNEW_M13612
Type:single initiation site
Name:Eomes_1
Description:Mus musculus eomesodermin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389118,478,191 - 118,478,251EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1201683 AgrOrtholog
Ensembl Genes ENSMUSG00000032446 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000035020 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000107393 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000118079 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000035020 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000111763 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000150633 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-box_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-box_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_T-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13813 UniProtKB/Swiss-Prot
MGD MGI:1201683 ENTREZGENE
NCBI Gene 13813 ENTREZGENE
PANTHER PTHR11267 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam T-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-box_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eomes PhenoGen
PRINTS TBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBOX_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.200692 ENTREZGENE
UniProt EOMES_MOUSE UniProtKB/Swiss-Prot
  F6VSW9_MOUSE UniProtKB/TrEMBL
  O54839 ENTREZGENE
  Q5PSA9_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3UPL1 UniProtKB/Swiss-Prot
  Q52KJ1 UniProtKB/Swiss-Prot
  Q8BN22 UniProtKB/Swiss-Prot
  Q9JJL1 UniProtKB/Swiss-Prot
  Q9QYG7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Eomes  eomesodermin    eomesodermin homolog (Xenopus laevis)  Symbol and/or name change 5135510 APPROVED