Mesp1 (mesoderm posterior 1) - Rat Genome Database

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Gene: Mesp1 (mesoderm posterior 1) Mus musculus
Analyze
Symbol: Mesp1
Name: mesoderm posterior 1
RGD ID: 1323369
MGI Page MGI
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including heart development; regulation of cell fate specification; and regulation of gene expression. Localizes to nucleus. Is expressed in several structures, including allantois; central nervous system; embryo mesenchyme; primitive streak; and sensory organ. Orthologous to human MESP1 (mesoderm posterior bHLH transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 5-fluorouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHc; bHLHc5; mesoderm posterior protein 1; MGC159208; MGC159210
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,441,989 - 79,443,338 (-)NCBIGRCm39mm39
GRCm39 Ensembl779,441,989 - 79,443,536 (-)Ensembl
GRCm38779,792,241 - 79,793,590 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,792,241 - 79,793,788 (-)EnsemblGRCm38mm10GRCm38
MGSCv37786,937,127 - 86,938,476 (-)NCBIGRCm37mm9NCBIm37
MGSCv36779,665,760 - 79,667,119 (-)NCBImm8
Celera777,191,445 - 77,192,794 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cardiac atrium formation  (ISO)
cardiac cell fate determination  (IDA)
cardiac muscle cell differentiation  (ISO)
cardiac vascular smooth muscle cell differentiation  (ISO)
cardiac ventricle formation  (ISO)
cardioblast anterior-lateral migration  (IEP)
cardioblast migration  (IMP)
cardioblast migration to the midline involved in heart field formation  (IMP)
embryonic heart tube morphogenesis  (IMP)
endothelial cell differentiation  (ISO)
gastrulation  (IEP)
gene expression  (IMP)
growth involved in heart morphogenesis  (IMP)
heart looping  (IMP)
heart morphogenesis  (IBA,IMP)
lateral mesoderm development  (IEP)
mesoderm formation  (IBA)
mesodermal cell migration  (IGI)
multicellular organism development  (IEA)
negative regulation of endodermal cell fate specification  (IDA)
negative regulation of mesodermal cell fate specification  (IDA)
negative regulation of transcription, DNA-templated  (IDA)
neurogenesis  (ISO)
Notch signaling pathway  (IEA)
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway  (IDA)
positive regulation of hepatocyte differentiation  (IDA)
positive regulation of Notch signaling pathway  (IDA)
positive regulation of Notch signaling pathway involved in heart induction  (IDA)
positive regulation of striated muscle cell differentiation  (IDA)
positive regulation of transcription by RNA polymerase II  (IMP,ISO)
positive regulation of transcription, DNA-templated  (IDA)
regulation of transcription by RNA polymerase II  (IBA)
secondary heart field specification  (IDA)
signal transduction involved in regulation of gene expression  (IDA)
sinoatrial node cell differentiation  (ISO)
sinus venosus morphogenesis  (IMP)
somite rostral/caudal axis specification  (IBA)

Cellular Component
nucleus  (IBA,IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
aberrant origin of the right subclavian artery  (IAGP)
abnormal accessory nerve morphology  (IAGP)
abnormal aortic arch morphology  (IAGP)
abnormal atrioventricular cushion morphology  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal cardiac epithelial to mesenchymal transition  (IAGP)
abnormal cardiac neural crest cell migration  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cardiogenic mesoderm morphology  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal common carotid artery morphology  (IAGP)
abnormal cranial neural crest cell migration  (IAGP)
abnormal ectoderm development  (IAGP)
abnormal embryo development  (IAGP)
abnormal embryonic growth/weight/body size  (IAGP)
abnormal endoderm development  (IAGP)
abnormal fourth pharyngeal arch artery morphology  (IAGP)
abnormal fourth pharyngeal pouch morphology  (IAGP)
abnormal gastrulation  (IAGP)
abnormal heart development  (IAGP)
abnormal heart left atrium auricular region morphology  (IAGP)
abnormal heart looping  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart shape  (IAGP)
abnormal heart tube morphology  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal mandibular nerve branching  (IAGP)
abnormal mesenchyme morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal neural crest cell migration  (IAGP)
abnormal neural fold formation  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal paraxial mesoderm morphology  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal pharyngeal arch morphology  (IAGP)
abnormal primitive streak formation  (IAGP)
abnormal primitive streak morphology  (IAGP)
abnormal sarcomere morphology  (IAGP)
abnormal sixth pharyngeal arch artery morphology  (IAGP)
abnormal third pharyngeal arch artery morphology  (IAGP)
abnormal trabecula carnea morphology  (IAGP)
abnormal vagus nerve morphology  (IAGP)
abnormal vertebrae morphology  (IAGP)
absent fourth pharyngeal arch  (IAGP)
absent fourth pharyngeal arch artery  (IAGP)
absent heart  (IAGP)
absent mesoderm  (IAGP)
absent paraxial mesoderm  (IAGP)
absent sixth pharyngeal arch  (IAGP)
absent sixth pharyngeal arch artery  (IAGP)
absent somites  (IAGP)
absent third pharyngeal arch  (IAGP)
absent third pharyngeal arch artery  (IAGP)
athymia  (IAGP)
atrial septal defect  (IAGP)
atrioventricular septal defect  (IAGP)
bicuspid aortic valve  (IAGP)
bicuspid pulmonary valve  (IAGP)
cardia bifida  (IAGP)
common atrium  (IAGP)
common ventricle  (IAGP)
decreased body length  (IAGP)
decreased cell proliferation  (IAGP)
decreased embryo size  (IAGP)
decreased heart right ventricle size  (IAGP)
decreased somite size  (IAGP)
delayed embryo turning  (IAGP)
delayed neural tube closure  (IAGP)
dilated heart left ventricle  (IAGP)
disorganized embryonic tissue  (IAGP)
double outlet right ventricle  (IAGP)
ear lobe hypoplasia  (IAGP)
edema  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enlarged heart  (IAGP)
failure of initiation of embryo turning  (IAGP)
fusion of vertebral arches  (IAGP)
glossopharyngeal nerve hypoplasia  (IAGP)
heart right ventricle hypoplasia  (IAGP)
hemorrhage  (IAGP)
increased apoptosis  (IAGP)
lethality during fetal growth through weaning, incomplete penetrance  (IAGP)
microcephaly  (IAGP)
myocardial trabeculae hypoplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
overriding aortic valve  (IAGP)
pericardial edema  (IAGP)
pericardial effusion  (IAGP)
persistent truncus arteriosis  (IAGP)
pharynx hypoplasia  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
rib fusion  (IAGP)
right aortic arch  (IAGP)
second pharyngeal arch hypoplasia  (IAGP)
thin myocardium  (IAGP)
third pharyngeal arch hypoplasia  (IAGP)
thymus hypoplasia  (IAGP)
transposition of great arteries  (IAGP)
ventricular septal defect  (IAGP)
vertebral fusion  (IAGP)
References

Additional References at PubMed
PMID:8787751   PMID:9242490   PMID:9739106   PMID:10330372   PMID:10349636   PMID:10393122   PMID:10837126   PMID:10887078   PMID:10906448   PMID:11042159   PMID:11076861   PMID:11171400  
PMID:11562355   PMID:11578861   PMID:12381664   PMID:12477932   PMID:12490556   PMID:14610273   PMID:15677726   PMID:16141072   PMID:16141073   PMID:16284121   PMID:16317723   PMID:16554359  
PMID:16720879   PMID:16914493   PMID:16996494   PMID:17074316   PMID:17107996   PMID:17117436   PMID:17259303   PMID:17306789   PMID:17825816   PMID:18000065   PMID:18287559   PMID:18297060  
PMID:18297729   PMID:18328678   PMID:18440989   PMID:18462699   PMID:18547789   PMID:18557763   PMID:18593549   PMID:18593559   PMID:18593560   PMID:18617001   PMID:18680740   PMID:18832392  
PMID:18849530   PMID:18981480   PMID:19165826   PMID:19201948   PMID:19389367   PMID:19476657   PMID:19521566   PMID:19531353   PMID:19564151   PMID:19619645   PMID:19855134   PMID:20035084  
PMID:20040491   PMID:20230754   PMID:20691899   PMID:20727874   PMID:20727876   PMID:21089073   PMID:21098559   PMID:21224256   PMID:21294146   PMID:21383076   PMID:21425080   PMID:21632880  
PMID:21822279   PMID:21829519   PMID:21873635   PMID:21989917   PMID:22040871   PMID:22040872   PMID:22178153   PMID:22367967   PMID:22402664   PMID:22581563   PMID:22659386   PMID:22664175  
PMID:22698281   PMID:22711842   PMID:22778034   PMID:23011393   PMID:23041177   PMID:23093675   PMID:23112163   PMID:23184148   PMID:23185234   PMID:23261931   PMID:23341629   PMID:23352431  
PMID:23417899   PMID:23438573   PMID:23526457   PMID:23642367   PMID:23704920   PMID:23747598   PMID:23872235   PMID:23945394   PMID:24052814   PMID:24186978   PMID:24613616   PMID:24632501  
PMID:24657234   PMID:24698271   PMID:24705356   PMID:24748541   PMID:24821700   PMID:24843018   PMID:24895408   PMID:24920580   PMID:25150979   PMID:25209980   PMID:25220152   PMID:25242040  
PMID:25296024   PMID:25416281   PMID:25560321   PMID:25605943   PMID:25670795   PMID:25694434   PMID:25703143   PMID:25851587   PMID:25977363   PMID:25992544   PMID:26088191   PMID:26102480  
PMID:26205879   PMID:26295701   PMID:26384464   PMID:26387456   PMID:26489465   PMID:26565905   PMID:26598235   PMID:26725109   PMID:26771351   PMID:26932671   PMID:27005988   PMID:27131741  
PMID:27185833   PMID:27256596   PMID:27435625   PMID:27493992   PMID:27512039   PMID:27518902   PMID:27538477   PMID:27546376   PMID:27606604   PMID:27725084   PMID:27864380   PMID:27894818  
PMID:28177282   PMID:28239148   PMID:28357999   PMID:28438970   PMID:28446132   PMID:28791750   PMID:28794185   PMID:28947535   PMID:29061339   PMID:29069601   PMID:29202929   PMID:29371425  
PMID:29467410   PMID:29534062   PMID:29653101   PMID:30100166   PMID:30375332   PMID:30936115   PMID:31178404   PMID:31358536   PMID:31420575   PMID:31590918   PMID:31719045   PMID:31761621  
PMID:32041892   PMID:32203821   PMID:32561646   PMID:32800757   PMID:33082351   PMID:33086060   PMID:33201874   PMID:33298461  


Genomics

Comparative Map Data
Mesp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,441,989 - 79,443,338 (-)NCBIGRCm39mm39
GRCm39 Ensembl779,441,989 - 79,443,536 (-)Ensembl
GRCm38779,792,241 - 79,793,590 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,792,241 - 79,793,788 (-)EnsemblGRCm38mm10GRCm38
MGSCv37786,937,127 - 86,938,476 (-)NCBIGRCm37mm9NCBIm37
MGSCv36779,665,760 - 79,667,119 (-)NCBImm8
Celera777,191,445 - 77,192,794 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.16NCBI
MESP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1589,748,661 - 89,751,310 (-)EnsemblGRCh38hg38GRCh38
GRCh381589,734,772 - 89,751,309 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371590,293,098 - 90,294,540 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361588,094,110 - 88,095,552 (-)NCBINCBI36hg18NCBI36
Celera1566,695,858 - 66,697,300 (-)NCBI
Cytogenetic Map15q26.1NCBI
HuRef1566,406,054 - 66,407,496 (-)NCBIHuRef
CHM1_11590,133,926 - 90,135,368 (-)NCBICHM1_1
Mesp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21133,738,357 - 133,739,875 (-)NCBI
Rnor_6.0 Ensembl1141,532,390 - 141,533,908 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01141,532,390 - 141,533,908 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01142,493,452 - 142,494,970 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,571,777 - 135,573,295 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11135,650,456 - 135,651,437 (-)NCBI
Celera1125,801,663 - 125,803,181 (-)NCBICelera
Cytogenetic Map1q31NCBI
MESP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11587,645,768 - 87,647,210 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1587,645,768 - 87,647,210 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01568,440,626 - 68,441,935 (-)NCBIMhudiblu_PPA_v0panPan3
MESP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,738,333 - 52,739,962 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,738,366 - 52,739,755 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,372,284 - 55,373,854 (-)NCBI
ROS_Cfam_1.0353,155,122 - 53,156,692 (-)NCBI
UMICH_Zoey_3.1352,676,925 - 52,678,493 (-)NCBI
UNSW_CanFamBas_1.0352,886,866 - 52,888,431 (-)NCBI
UU_Cfam_GSD_1.0353,227,220 - 53,228,790 (-)NCBI
Mesp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640130,799,944 - 130,801,262 (+)NCBI
SpeTri2.0NW_00493648315,533,264 - 15,534,576 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MESP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl755,322,010 - 55,325,732 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1755,322,016 - 55,327,600 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2760,211,078 - 60,218,711 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MESP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1298,286,551 - 8,288,777 (-)NCBI
ChlSab1.1 Ensembl298,286,828 - 8,287,918 (-)Ensembl

Position Markers
RH126915  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38779,792,248 - 79,792,498UniSTSGRCm38
MGSCv37786,937,134 - 86,937,384UniSTSGRCm37
Celera777,191,452 - 77,191,702UniSTS
Cytogenetic Map7D3UniSTS
cM Map739.0UniSTS
UniSTS:493136  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38779,792,422 - 79,793,581UniSTSGRCm38
MGSCv37786,937,308 - 86,938,467UniSTSGRCm37
Celera777,191,626 - 77,192,785UniSTS
Cytogenetic Map7D3UniSTS
cM Map739.0UniSTS
UniSTS:495474  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38779,792,417 - 79,793,590UniSTSGRCm38
MGSCv37786,937,303 - 86,938,476UniSTSGRCm37
Celera777,191,621 - 77,192,794UniSTS
Cytogenetic Map7D3UniSTS
cM Map739.0UniSTS
Mesp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7D3UniSTS
cM Map745.16UniSTS
Mesp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7D3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7346321287493512Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3033306081485905Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730500000109400000Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73658059092745138Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736580590116817642Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73760000087400000Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined740024463103860803Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745512542119094307Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74873471382734859Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74950947983586207Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74954353083543642Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75147520685475345Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75147520685475345Mouse
13208555Lgth10_mbody length 10 (mouse)752000000126000000Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75250000086500000Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753600000143600000Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)755169841117223580Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75623976087493512Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)757300000134400000Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75767637391676604Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75767637391676604Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75767637391676604Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)762100000121800000Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)762100000124100000Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)762200000103100000Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76448567698485905Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76560000097300000Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765600000126900000Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)766139778100139778Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)766139778100139778Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76680000098700000Mouse
12801463Rta1_mretinal aging 1 (mouse)76751827989440781Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767640886101641032Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767640886101641032Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767640886101641032Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)768200000105800000Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)768200000119900000Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)768200000124600000Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)768200000125400000Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768716387102716494Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)770300000120900000Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770493929104494171Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772614164106614164Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7320735792932955Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773400000126100000Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773500000143600000Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)774076757108076757Mouse
4142212Png1_mPostnatal growth 1 (mouse)Not determined7467637392745138Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)775200000122600000Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)775200000122600000Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775745007109745138Mouse
14746989Manh62_mmandible shape 62 (mouse)776093321110093321Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)779000000137300000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:117
Interacting mature miRNAs:121
Transcripts:ENSMUST00000032760
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000032760   ⟹   ENSMUSP00000032760
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl779,792,241 - 79,793,788 (-)Ensembl
RefSeq Acc Id: NM_008588   ⟹   NP_032614
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39779,441,989 - 79,443,338 (-)NCBI
GRCm38779,792,241 - 79,793,590 (-)ENTREZGENE
MGSCv37786,937,127 - 86,938,476 (-)RGD
Celera777,191,445 - 77,192,794 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032614   ⟸   NM_008588
- UniProtKB: P97309 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000032760   ⟸   ENSMUST00000032760
Protein Domains
bHLH

Promoters
RGD ID:6841516
Promoter ID:MM_KWN:51256
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:OTTMUST00000061467
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36786,937,634 - 86,938,134 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107785 AgrOrtholog
Ensembl Genes ENSMUSG00000030544 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000032760 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000032760 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot
InterPro bHLH_dom UniProtKB/Swiss-Prot
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot
  Mesogenin/MesP UniProtKB/Swiss-Prot
KEGG Report mmu:17292 UniProtKB/Swiss-Prot
MGD MGI:107785 ENTREZGENE
NCBI Gene 17292 ENTREZGENE
PANTHER PTHR20937 UniProtKB/Swiss-Prot
Pfam HLH UniProtKB/Swiss-Prot
PhenoGen Mesp1 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot
SMART HLH UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot
UniProt MESP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9CVV5_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q059W2 UniProtKB/Swiss-Prot