Clpx (caseinolytic mitochondrial matrix peptidase chaperone subunit) - Rat Genome Database

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Gene: Clpx (caseinolytic mitochondrial matrix peptidase chaperone subunit) Mus musculus
Analyze
Symbol: Clpx
Name: caseinolytic mitochondrial matrix peptidase chaperone subunit
RGD ID: 1312579
MGI Page MGI
Description: Enables ATP binding activity and ATP hydrolysis activity. Predicted to be involved in ATP metabolic process and proteolysis involved in protein catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system. Human ortholog(s) of this gene implicated in erythropoietic protoporphyria. Orthologous to human CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; ATP-dependent clpX-like chaperone, mitochondrial; AU014732; caseinolytic peptidase X; caseinolytic protease X; caseinolytic protease X (E.coli); E330029I21
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39965,201,533 - 65,237,940 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl965,201,542 - 65,237,940 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38965,294,251 - 65,330,658 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl965,294,260 - 65,330,658 (+)Ensemblmm10GRCm38
MGSCv37965,142,102 - 65,178,465 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36965,092,315 - 65,128,648 (+)NCBIMGSCv36mm8
Celera962,524,684 - 62,560,554 (+)NCBICelera
Cytogenetic Map9CNCBI
cM Map935.22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
amiodarone  (EXP)
Aroclor 1254  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
Brodifacoum  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
chromium(6+)  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP)
cyclosporin A  (EXP,ISO)
deguelin  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
doxorubicin  (EXP)
epoxiconazole  (EXP)
folic acid  (EXP)
furan  (ISO)
glafenine  (ISO)
glyphosate  (EXP)
graphene oxide  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
josamycin  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methotrexate  (EXP)
methylphenidate  (EXP)
Muraglitazar  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
nimesulide  (ISO)
ochratoxin A  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (EXP)
propiconazole  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (EXP)
succimer  (EXP)
tetrachloromethane  (EXP)
titanium dioxide  (EXP,ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10347188   PMID:10349636   PMID:10922068   PMID:11003706   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11790733   PMID:12477932   PMID:12819125   PMID:12865426  
PMID:12904583   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18614015   PMID:21267068   PMID:21873635   PMID:23851121   PMID:24194600   PMID:26142927   PMID:27746211   PMID:28130547  
PMID:28378742   PMID:29199018   PMID:30333137   PMID:30550785   PMID:32376682   PMID:32467259   PMID:32560809   PMID:34280433   PMID:34943861   PMID:36114006   PMID:37442135   PMID:37798322  
PMID:38355793   PMID:38397478   PMID:38927630  


Genomics

Comparative Map Data
Clpx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39965,201,533 - 65,237,940 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl965,201,542 - 65,237,940 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38965,294,251 - 65,330,658 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl965,294,260 - 65,330,658 (+)Ensemblmm10GRCm38
MGSCv37965,142,102 - 65,178,465 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36965,092,315 - 65,128,648 (+)NCBIMGSCv36mm8
Celera962,524,684 - 62,560,554 (+)NCBICelera
Cytogenetic Map9CNCBI
cM Map935.22NCBI
CLPX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381565,148,219 - 65,185,342 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1565,148,219 - 65,185,342 (-)Ensemblhg38GRCh38
GRCh371565,440,557 - 65,477,680 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361563,229,837 - 63,264,616 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341563,229,836 - 63,264,616NCBI
Celera1542,320,894 - 42,355,668 (-)NCBICelera
Cytogenetic Map15q22.31NCBI
HuRef1542,267,359 - 42,302,239 (-)NCBIHuRef
CHM1_11565,562,516 - 65,597,291 (-)NCBICHM1_1
T2T-CHM13v2.01562,957,572 - 62,994,692 (-)NCBIT2T-CHM13v2.0
Clpx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8874,700,602 - 74,740,244 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl874,700,662 - 74,744,762 (+)EnsemblGRCr8
mRatBN7.2865,805,460 - 65,845,643 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl865,805,511 - 65,845,082 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx871,317,986 - 71,357,032 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0869,590,993 - 69,630,038 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0867,460,707 - 67,499,698 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0870,789,137 - 70,843,133 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl870,789,256 - 70,843,123 (+)Ensemblrn6Rnor6.0
Rnor_5.0870,480,691 - 70,535,370 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4869,530,991 - 69,572,018 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera865,203,579 - 65,242,568 (+)NCBICelera
RGSC_v3.1869,550,044 - 69,591,072 (+)NCBI
Cytogenetic Map8q24NCBI
Clpx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545010,256,124 - 10,289,832 (+)Ensembl
ChiLan1.0NW_00495545010,256,124 - 10,289,832 (+)NCBIChiLan1.0ChiLan1.0
CLPX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21654,396,633 - 54,435,420 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11558,565,991 - 58,606,987 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01544,088,070 - 44,128,730 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11562,372,738 - 62,412,746 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1562,374,068 - 62,412,746 (-)EnsemblpanPan2panpan1.1
CLPX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13029,515,907 - 29,560,318 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3029,510,694 - 29,559,937 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3029,445,815 - 29,489,746 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03029,705,466 - 29,749,290 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3029,705,291 - 29,749,300 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13029,637,716 - 29,681,446 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03029,699,612 - 29,743,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03029,939,983 - 29,984,378 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Clpx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640107,599,687 - 107,636,884 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647125,444,711 - 25,484,988 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647125,447,750 - 25,484,956 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLPX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1163,173,891 - 163,222,031 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11163,173,887 - 163,222,067 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21180,698,287 - 180,747,236 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CLPX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12618,401,593 - 18,441,286 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2618,401,798 - 18,440,915 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666048122,992,365 - 123,036,751 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clpx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247817,320,604 - 7,362,403 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247817,320,647 - 7,362,403 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Clpx
1360 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:507
Count of miRNA genes:245
Interacting mature miRNAs:270
Transcripts:ENSMUST00000015501, ENSMUST00000113824, ENSMUST00000147279, ENSMUST00000148632
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
13525007Lfhrvq1_mlow frequency time index heart rate varaiblity, QTL 1 (mouse)95878431868556008Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95936994693370128Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95455996088559960Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse
4141676Neogq1_mneonatal growth QTL 1 (mouse)Not determined95780504786121973Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
13525008Hrtiq1_mheart rate time index, QTL 1 (mouse)95242609868556008Mouse
1301965Vmbic5_mventral midbrain iron content 5 (mouse)Not determined95759149265831177Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95936994693370128Mouse
11081165Psl6_mpromotion susceptibility QTL 6 (mouse)96504119195522808Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95902438793024534Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95936994693370128Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94942029867151448Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95902438793024534Mouse
1301611Lrnx3_mlearning contextual 3 (mouse)Not determined96214976796149881Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4659767165831177Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95643910890439255Mouse
1301549Bbaa9_mB.burgdorferi-associated arthritis 9 (mouse)Not determined95780504771481754Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse

Markers in Region
AU014732  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38965,330,027 - 65,330,230UniSTSGRCm38
MGSCv37965,177,834 - 65,178,037UniSTSGRCm37
Celera962,559,923 - 62,560,126UniSTS
Cytogenetic Map9CUniSTS
cM Map936.5UniSTS
Whitehead/MRC_RH9629.16UniSTS
BB208476  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38965,319,388 - 65,319,471UniSTSGRCm38
MGSCv37965,167,195 - 65,167,278UniSTSGRCm37
Celera962,549,576 - 62,549,659UniSTS
Cytogenetic Map9CUniSTS
cM Map936.5UniSTS
Whitehead/MRC_RH9630.0UniSTS
Clpx  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9CUniSTS
cM Map936.5UniSTS
cM Map936.5UniSTS
RH126994  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38965,303,062 - 65,303,271UniSTSGRCm38
MGSCv37965,150,869 - 65,151,078UniSTSGRCm37
Celera962,533,445 - 62,533,654UniSTS
Cytogenetic Map9CUniSTS
cM Map938.0UniSTS
Whitehead/MRC_RH9629.78UniSTS
Clpx  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9CUniSTS
cM Map936.5UniSTS
Clpx  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9CUniSTS
cM Map936.5UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001044389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003947922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_379423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF134983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV237409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC061153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY784827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX763671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000015501   ⟹   ENSMUSP00000015501
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl965,201,542 - 65,237,939 (+)Ensembl
GRCm38.p6 Ensembl965,294,260 - 65,330,657 (+)Ensembl
Ensembl Acc Id: ENSMUST00000113824   ⟹   ENSMUSP00000109455
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl965,201,577 - 65,237,940 (+)Ensembl
GRCm38.p6 Ensembl965,294,295 - 65,330,658 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147279   ⟹   ENSMUSP00000116377
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl965,217,434 - 65,226,019 (+)Ensembl
GRCm38.p6 Ensembl965,310,152 - 65,318,737 (+)Ensembl
Ensembl Acc Id: ENSMUST00000148632
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl965,201,614 - 65,216,512 (+)Ensembl
GRCm38.p6 Ensembl965,294,332 - 65,309,230 (+)Ensembl
RefSeq Acc Id: NM_001044389   ⟹   NP_001037854
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39965,201,542 - 65,237,940 (+)NCBI
GRCm38965,294,260 - 65,330,658 (+)NCBI
MGSCv37965,142,102 - 65,178,465 (+)RGD
Celera962,524,649 - 62,560,554 (+)NCBI
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_011802   ⟹   NP_035932
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39965,201,542 - 65,237,940 (+)NCBI
GRCm38965,294,260 - 65,330,658 (+)NCBI
MGSCv37965,142,102 - 65,178,465 (+)RGD
Celera962,524,649 - 62,560,554 (+)NCBI
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_003947922
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39965,201,533 - 65,237,931 (+)NCBI
GRCm38965,294,251 - 65,330,644 (+)NCBI
Sequence:
RefSeq Acc Id: XR_379423
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39965,201,533 - 65,237,931 (+)NCBI
GRCm38965,294,251 - 65,330,644 (+)NCBI
Sequence:
RefSeq Acc Id: NP_035932   ⟸   NM_011802
- Peptide Label: isoform 1
- UniProtKB: Q9WVD1 (UniProtKB/Swiss-Prot),   Q9JHS4 (UniProtKB/Swiss-Prot),   E9QLZ8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001037854   ⟸   NM_001044389
- Peptide Label: isoform 2
- UniProtKB: Q6P8N8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000109455   ⟸   ENSMUST00000113824
Ensembl Acc Id: ENSMUSP00000116377   ⟸   ENSMUST00000147279
Ensembl Acc Id: ENSMUSP00000015501   ⟸   ENSMUST00000015501
Protein Domains
AAA+ ATPase   ClpX-type ZB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JHS4-F1-model_v2 AlphaFold Q9JHS4 1-634 view protein structure

Promoters
RGD ID:6844334
Promoter ID:MM_KWN:57762
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001044389,   OTTMUST00000078915,   UC009QDA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36965,141,106 - 65,142,302 (+)MPROMDB
RGD ID:8669978
Promoter ID:EPDNEW_M13020
Type:initiation region
Name:Clpx_1
Description:Mus musculus caseinolytic mitochondrial matrix peptidase chaperonesubunit , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38965,294,291 - 65,294,351EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1346017 AgrOrtholog
Ensembl Genes ENSMUSG00000015357 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000015501 ENTREZGENE
  ENSMUST00000015501.11 UniProtKB/Swiss-Prot
  ENSMUST00000113824 ENTREZGENE
Gene3D-CATH 1.10.8.60 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  ATP-dep_Clp_protease_ClpX UniProtKB/Swiss-Prot
  ATPase_AAA_core UniProtKB/Swiss-Prot
  Clp_ATPase_C UniProtKB/Swiss-Prot
  Clp_protease_ATP-bd_su_ClpX UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Znf_CppX_C4 UniProtKB/Swiss-Prot
KEGG Report mmu:270166 UniProtKB/Swiss-Prot
MGD MGI:1346017 ENTREZGENE
NCBI Gene Clpx ENTREZGENE
PANTHER ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL UniProtKB/Swiss-Prot
  ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED UniProtKB/Swiss-Prot
Pfam AAA_2 UniProtKB/Swiss-Prot
  ClpB_D2-small UniProtKB/Swiss-Prot
PhenoGen Clpx PhenoGen
PROSITE CLPX_ZB UniProtKB/Swiss-Prot
SMART AAA UniProtKB/Swiss-Prot
  ClpB_D2-small UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt CLPX_MOUSE UniProtKB/Swiss-Prot
  E9QLZ8 ENTREZGENE
  F7BB92_MOUSE UniProtKB/TrEMBL
  Q3TNL0_MOUSE UniProtKB/TrEMBL
  Q6P8N8 ENTREZGENE, UniProtKB/TrEMBL
  Q8BRZ3_MOUSE UniProtKB/TrEMBL
  Q8C4Z5_MOUSE UniProtKB/TrEMBL
  Q9JHS4 ENTREZGENE
  Q9WVD1 ENTREZGENE
UniProt Secondary E9QLZ8 UniProtKB/Swiss-Prot
  Q9WVD1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-09-25 Clpx  caseinolytic mitochondrial matrix peptidase chaperone subunit  Clpx  caseinolytic protease X (E.coli)  Symbol and/or name change 5135510 APPROVED
2024-08-21 Clpx  caseinolytic protease X (E.coli)  Clpx  caseinolytic mitochondrial matrix peptidase chaperone subunit  Symbol and/or name change 5135510 APPROVED
2014-06-10 Clpx  caseinolytic mitochondrial matrix peptidase chaperone subunit    caseinolytic peptidase X (E.coli)  Symbol and/or name change 5135510 APPROVED