Ccdc59 (coiled-coil domain containing 59) - Rat Genome Database

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Gene: Ccdc59 (coiled-coil domain containing 59) Mus musculus
Analyze
Symbol: Ccdc59
Name: coiled-coil domain containing 59
RGD ID: 1323618
MGI Page MGI
Description: Predicted to be located in nucleus. Is expressed in early conceptus; embryo; extraembryonic component; oocyte; and primitive endoderm. Orthologous to human CCDC59 (coiled-coil domain containing 59); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 2300004H16Rik; coiled-coil domain-containing protein 59; D10Ertd718; D10Ertd718e; thyroid transcription factor 1-associated protein 26; TTF-1-associated protein 26
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910105,677,340 - 105,683,371 (+)NCBIGRCm39mm39
GRCm39 Ensembl10105,676,928 - 105,683,694 (+)Ensembl
GRCm3810105,841,479 - 105,847,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10105,841,067 - 105,847,833 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710105,278,535 - 105,284,566 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610105,245,589 - 105,251,620 (+)NCBImm8
Celera10107,790,826 - 107,796,856 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:23375831  
PMID:32325033  


Genomics

Comparative Map Data
Ccdc59
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910105,677,340 - 105,683,371 (+)NCBIGRCm39mm39
GRCm39 Ensembl10105,676,928 - 105,683,694 (+)Ensembl
GRCm3810105,841,479 - 105,847,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10105,841,067 - 105,847,833 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710105,278,535 - 105,284,566 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610105,245,589 - 105,251,620 (+)NCBImm8
Celera10107,790,826 - 107,796,856 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.12NCBI
CCDC59
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1282,223,681 - 82,358,805 (-)EnsemblGRCh38hg38GRCh38
GRCh381282,352,303 - 82,358,805 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371282,746,082 - 82,752,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361281,270,220 - 81,276,330 (-)NCBINCBI36hg18NCBI36
Celera1282,413,647 - 82,420,144 (-)NCBI
Cytogenetic Map12q21.31NCBI
HuRef1279,803,324 - 79,809,821 (-)NCBIHuRef
CHM1_11282,711,940 - 82,718,437 (-)NCBICHM1_1
Ccdc59
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2741,142,760 - 41,149,143 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl741,142,760 - 41,149,143 (+)Ensembl
Rnor_6.0747,928,138 - 47,934,690 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl747,928,060 - 47,934,929 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0747,942,423 - 47,948,975 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4744,496,241 - 44,502,624 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1744,516,930 - 44,522,810 (+)NCBI
Celera738,018,929 - 38,025,316 (+)NCBICelera
Cytogenetic Map7q21NCBI
Ccdc59
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540520,731,464 - 20,738,657 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540520,732,649 - 20,738,678 (-)NCBIChiLan1.0ChiLan1.0
CCDC59
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11282,976,079 - 82,981,650 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1282,976,079 - 82,981,650 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01279,864,105 - 79,873,182 (-)NCBIMhudiblu_PPA_v0panPan3
CCDC59
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11524,364,510 - 24,373,567 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1524,364,779 - 24,373,419 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1524,795,481 - 24,804,911 (-)NCBI
ROS_Cfam_1.01524,743,406 - 24,752,836 (-)NCBI
UMICH_Zoey_3.11524,320,972 - 24,330,182 (-)NCBI
UNSW_CanFamBas_1.01524,369,767 - 24,379,043 (-)NCBI
UU_Cfam_GSD_1.01524,610,635 - 24,620,062 (-)NCBI
Ccdc59
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494535,897,608 - 35,905,140 (+)NCBI
SpeTri2.0NW_004936507330,481 - 337,810 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC59
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl599,358,338 - 99,364,091 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1599,358,726 - 99,364,092 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25104,173,569 - 104,178,937 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCDC59
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_023666037167,593,487 - 167,599,644 (+)NCBIVero_WHO_p1.0
Ccdc59
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248371,687,403 - 1,693,619 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BE133929  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810105,847,509 - 105,847,654UniSTSGRCm38
MGSCv3710105,284,565 - 105,284,710UniSTSGRCm37
Celera10107,796,855 - 107,797,000UniSTS
Cytogenetic Map10D1UniSTS
cM Map1059.0UniSTS
Whitehead/MRC_RH101164.51UniSTS
RH136239  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810105,847,049 - 105,847,254UniSTSGRCm38
MGSCv3710105,284,105 - 105,284,310UniSTSGRCm37
Celera10107,796,396 - 107,796,601UniSTS
Cytogenetic Map10D1UniSTS
cM Map1059.0UniSTS
D10Ertd718e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810105,847,185 - 105,847,409UniSTSGRCm38
MGSCv3710105,284,241 - 105,284,465UniSTSGRCm37
Celera10107,796,532 - 107,796,755UniSTS
Cytogenetic Map10D1UniSTS
cM Map1059.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1045000000116100000Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045600000120800000Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059500000122500000Mouse
13208560Wght9_mweight 9 (mouse)1060000000121000000Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1064100000116100000Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067500000111900000Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1068000000125000000Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073671039107671185Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1074151384125680038Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1074151384125680038Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075502706109502905Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75502706109502905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075502706109502905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078545406112545406Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082242550116242550Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082473556116473795Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082473556116473795Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082473556116473795Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082473556116473795Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082473556116473795Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082473556116473795Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082556941116557090Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83181141117181274Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084243786122205623Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84243786122205623Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84243786122205623Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84243786122205623Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84243786122205623Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084243786122205623Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084243786122205623Mouse
1357638Cia29_mcollagen induced arthritis 29 (mouse)Not determined1085619118118661448Mouse
1300797Sluc22_msusceptibility to lung cancer 22 (mouse)Not determined1086877747120877895Mouse
1301520Uvbi1_mUVB induced immunosuppression 1 (mouse)Not determined1087073224121073368Mouse
1300908Insq4_minsulin QTL 4 (mouse)Not determined1087073224121073368Mouse
1300921Skl4_mskeletal size (tail length) 4 (mouse)Not determined1088252393122252530Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined89000595123000595Mouse
1301758Fcsa3_mfemoral cross-sectional area 3 (mouse)Not determined1090091790124091893Mouse
11039516Ltpr5_mLeishmania tropica response 5 (mouse)1090671039125739363Mouse
13208554Lgth11_mbody length 11 (mouse)1091000000121000000Mouse
12910821Ogrq4_moverall growth rate QTL 4 (mouse)1092333194107484128Mouse
4142074Tmevp2_mTheiler's murine encephalomyelitis virus persistence 2 (mouse)Not determined92894079111732414Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097381196130694993Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097381196130694993Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397381196130694993Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097381196130694993Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097700000130694993Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97922739130694993Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099384730130694993Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099384730130694993Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099384730130694993Mouse
11059544Lmr32_mleishmaniasis resistance 32 (mouse)1099473556116384957Mouse
11059552Lmr32c_mleishmaniasis resistance 32c (mouse)1099473556116384957Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10101150611130694993Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10101150611130694993Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101661259130694993Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101661259130694993Mouse
26884388Skwq7_mskull length QTL 7, 10 week (mouse)10101900000113900000Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102671003130694993Mouse
27226725Tibw1_mtibia width 1, proximal, 5 week (mouse)10102900000123400000Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10103011947130694993Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10103066603130694993Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103407822130694993Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104274116130694993Mouse
14746996Manh69_mmandible shape 69 (mouse)10104927733130694993Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105205399130694993Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105205399130694993Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105205399130694993Mouse
4141269Ipng2_mimprinted postnatal growth 2 (mouse)Not determined105252393118661448Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105343808130694993Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105343808130694993Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105343808130694993Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:393
Count of miRNA genes:316
Interacting mature miRNAs:342
Transcripts:ENSMUST00000020049, ENSMUST00000133538, ENSMUST00000155406
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000020049   ⟹   ENSMUSP00000020049
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10105,676,928 - 105,683,694 (+)Ensembl
GRCm38.p6 Ensembl10105,841,067 - 105,847,833 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133538
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10105,676,928 - 105,683,694 (+)Ensembl
GRCm38.p6 Ensembl10105,841,067 - 105,847,833 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155406
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10105,677,365 - 105,678,843 (+)Ensembl
GRCm38.p6 Ensembl10105,841,504 - 105,842,982 (+)Ensembl
RefSeq Acc Id: NM_025602   ⟹   NP_079878
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,677,340 - 105,683,371 (+)NCBI
GRCm3810105,841,479 - 105,847,510 (+)ENTREZGENE
MGSCv3710105,278,535 - 105,284,566 (+)RGD
Celera10107,790,826 - 107,796,856 (+)RGD
cM Map10 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_079878   ⟸   NM_025602
- UniProtKB: Q8R2N0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020049   ⟸   ENSMUST00000020049

Promoters
RGD ID:6819085
Promoter ID:MM_KWN:5553
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   MEF_B6
Transcripts:OTTMUST00000081572,   OTTMUST00000081573,   OTTMUST00000081574
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610105,278,139 - 105,278,639 (+)MPROMDB
RGD ID:8673202
Promoter ID:EPDNEW_M14632
Type:multiple initiation site
Name:Ccdc59_1
Description:Mus musculus coiled-coil domain containing 59 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810105,841,479 - 105,841,539EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1289302 AgrOrtholog
Ensembl Genes ENSMUSG00000019897 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000020049 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020049 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Fyv7/TAP26 UniProtKB/Swiss-Prot
KEGG Report mmu:52713 UniProtKB/Swiss-Prot
MGD MGI:1289302 ENTREZGENE
NCBI Gene 52713 ENTREZGENE
PANTHER PTHR15657 UniProtKB/Swiss-Prot
Pfam rRNA_processing UniProtKB/Swiss-Prot
PhenoGen Ccdc59 PhenoGen
PRINTS BR22PROTEIN UniProtKB/Swiss-Prot
UniProt Q8R2N0 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8BZ86 UniProtKB/Swiss-Prot
  Q9CR69 UniProtKB/Swiss-Prot
  Q9CV91 UniProtKB/Swiss-Prot