Mesd (mesoderm development LRP chaperone) - Rat Genome Database

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Gene: Mesd (mesoderm development LRP chaperone) Mus musculus
Analyze
Symbol: Mesd
Name: mesoderm development LRP chaperone
RGD ID: 1321195
MGI Page MGI
Description: Enables identical protein binding activity and low-density lipoprotein particle receptor binding activity. Involved in phagocytosis and positive regulation of skeletal muscle acetylcholine-gated channel clustering. Acts upstream of or within protein folding and protein localization to cell surface. Located in plasma membrane. Is expressed in several structures, including 4-cell stage embryo; genitourinary system; hemolymphoid system; liver; and ventricular layer. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 20. Orthologous to human MESD (mesoderm development LRP chaperone).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2210015O11Rik; AW537813; LDLR chaperone MESD; LRP chaperone MESD; Mesdc; Mesdc2; mesoderm development candidate 2; mesoderm development protein; MGC25959; mKIAA0081; ms; msd
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39783,533,074 - 83,549,519 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl783,533,674 - 83,550,740 (+)EnsemblGRCm39 Ensembl
GRCm38783,883,866 - 83,900,311 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl783,884,466 - 83,901,532 (+)EnsemblGRCm38mm10GRCm38
MGSCv37791,040,510 - 91,050,042 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36783,768,442 - 83,777,717 (+)NCBIMGSCv36mm8
Celera781,303,724 - 81,313,237 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1543902   PMID:1741389   PMID:8026341   PMID:8787751   PMID:8889548   PMID:10349636   PMID:10922068   PMID:10995574   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11247670  
PMID:11544199   PMID:12466851   PMID:12477932   PMID:12581525   PMID:12904583   PMID:14621295   PMID:15782199   PMID:16126904   PMID:16141072   PMID:16141073   PMID:16263759   PMID:16989816  
PMID:17488095   PMID:18505367   PMID:18974875   PMID:19636811   PMID:20446724   PMID:20562862   PMID:21267068   PMID:21337463   PMID:21397183   PMID:21397184   PMID:21397185   PMID:21731673  
PMID:21873635   PMID:21907199   PMID:23469146   PMID:24124512   PMID:24140340   PMID:26273529   PMID:27184668   PMID:31564437   PMID:32325033   PMID:32968282   PMID:36417873  


Genomics

Comparative Map Data
Mesd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39783,533,074 - 83,549,519 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl783,533,674 - 83,550,740 (+)EnsemblGRCm39 Ensembl
GRCm38783,883,866 - 83,900,311 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl783,884,466 - 83,901,532 (+)EnsemblGRCm38mm10GRCm38
MGSCv37791,040,510 - 91,050,042 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36783,768,442 - 83,777,717 (+)NCBIMGSCv36mm8
Celera781,303,724 - 81,313,237 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.35NCBI
MESD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381580,946,289 - 80,989,819 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1580,946,289 - 80,989,828 (-)EnsemblGRCh38hg38GRCh38
GRCh371581,238,630 - 81,282,160 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361579,055,150 - 79,069,260 (-)NCBINCBI36Build 36hg18NCBI36
Build 341579,055,149 - 79,069,190NCBI
Celera1558,205,577 - 58,219,691 (-)NCBICelera
Cytogenetic Map15q25.1NCBI
HuRef1558,026,433 - 58,040,476 (-)NCBIHuRef
CHM1_11581,386,040 - 81,400,150 (-)NCBICHM1_1
T2T-CHM13v2.01578,809,933 - 78,853,463 (-)NCBIT2T-CHM13v2.0
Mesd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81147,275,904 - 147,289,134 (+)NCBIGRCr8
mRatBN7.21137,866,707 - 137,879,999 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1137,874,242 - 137,879,999 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1145,816,564 - 145,822,227 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01152,985,572 - 152,991,235 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01145,860,769 - 145,866,432 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01146,030,211 - 146,043,097 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1146,037,426 - 146,043,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01146,958,854 - 146,971,740 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41140,167,851 - 140,173,514 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11140,246,256 - 140,251,920 (+)NCBI
Celera1129,895,204 - 129,900,875 (+)NCBICelera
Cytogenetic Map1q31NCBI
Mesd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541611,722,388 - 11,731,758 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541611,722,388 - 11,731,758 (-)NCBIChiLan1.0ChiLan1.0
MESD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21670,244,682 - 70,256,396 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11574,404,250 - 74,418,425 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01559,959,985 - 59,970,904 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11578,914,991 - 78,926,612 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1578,914,991 - 78,926,612 (-)Ensemblpanpan1.1panPan2
MESD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1356,698,417 - 56,709,632 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl356,705,479 - 56,709,536 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha359,350,175 - 59,358,594 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0357,123,157 - 57,131,586 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1356,634,053 - 56,642,467 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0356,840,034 - 56,848,443 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0357,178,945 - 57,187,386 (+)NCBIUU_Cfam_GSD_1.0
Mesd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640126,627,797 - 126,646,344 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648319,696,739 - 19,708,447 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648319,697,241 - 19,706,719 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MESD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl749,807,125 - 49,817,658 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1749,807,309 - 49,817,725 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2755,381,578 - 55,391,927 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MESD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1262,402,719 - 2,413,682 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl262,402,709 - 2,416,923 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048139,474,005 - 139,484,970 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mesd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476820,863,697 - 20,871,875 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476820,863,804 - 20,871,867 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mesd
664 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1863
Count of miRNA genes:774
Interacting mature miRNAs:1010
Transcripts:ENSMUST00000094215, ENSMUST00000130103, ENSMUST00000138803, ENSMUST00000153377
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76644974898349207Mouse
12801463Rta1_mretinal aging 1 (mouse)76716802789089989Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7285710592582163Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
4142212Png1_mPostnatal growth 1 (mouse)Not determined7432612192394346Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse

Markers in Region
AW537813  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38783,898,663 - 83,898,746UniSTSGRCm38
MGSCv37791,047,173 - 91,047,256UniSTSGRCm37
Celera781,310,390 - 81,310,473UniSTS
Cytogenetic Map7D3UniSTS
cM Map748.35UniSTS
Whitehead/MRC_RH7893.53UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001374090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_023403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_164323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_164324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_164325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC154141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF311213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU054434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000094215   ⟹   ENSMUSP00000091768
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl783,541,208 - 83,550,740 (+)Ensembl
GRCm38.p6 Ensembl783,892,000 - 83,901,532 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130103   ⟹   ENSMUSP00000114218
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl783,541,210 - 83,546,975 (+)Ensembl
GRCm38.p6 Ensembl783,892,002 - 83,897,767 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138803
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl783,533,674 - 83,547,148 (+)Ensembl
GRCm38.p6 Ensembl783,884,466 - 83,897,940 (+)Ensembl
RefSeq Acc Id: ENSMUST00000153377   ⟹   ENSMUSP00000115696
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl783,541,538 - 83,547,288 (+)Ensembl
GRCm38.p6 Ensembl783,892,330 - 83,898,080 (+)Ensembl
RefSeq Acc Id: ENSMUST00000207373
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl783,544,261 - 83,547,062 (+)Ensembl
GRCm38.p6 Ensembl783,895,053 - 83,897,854 (+)Ensembl
RefSeq Acc Id: NM_001374090   ⟹   NP_001361019
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39783,533,074 - 83,549,519 (+)NCBI
GRCm38783,883,866 - 83,900,311 (+)NCBI
Sequence:
RefSeq Acc Id: NM_023403   ⟹   NP_075892
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39783,541,474 - 83,549,519 (+)NCBI
GRCm38783,892,266 - 83,900,311 (+)NCBI
MGSCv37791,040,510 - 91,050,042 (+)RGD
Celera781,303,724 - 81,313,237 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_164323
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39783,541,474 - 83,549,519 (+)NCBI
GRCm38783,892,266 - 83,900,311 (+)NCBI
Sequence:
RefSeq Acc Id: NR_164324
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39783,533,597 - 83,549,519 (+)NCBI
GRCm38783,884,389 - 83,900,311 (+)NCBI
Sequence:
RefSeq Acc Id: NR_164325
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39783,538,550 - 83,549,519 (+)NCBI
GRCm38783,889,342 - 83,900,311 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_075892   ⟸   NM_023403
- Peptide Label: isoform 1 precursor
- UniProtKB: Q91WK8 (UniProtKB/Swiss-Prot),   Q8CCX7 (UniProtKB/Swiss-Prot),   Q8C611 (UniProtKB/Swiss-Prot),   Q9CVB9 (UniProtKB/Swiss-Prot),   Q9ERE7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001361019   ⟸   NM_001374090
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000114218   ⟸   ENSMUST00000130103
RefSeq Acc Id: ENSMUSP00000091768   ⟸   ENSMUST00000094215
RefSeq Acc Id: ENSMUSP00000115696   ⟸   ENSMUST00000153377

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ERE7-F1-model_v2 AlphaFold Q9ERE7 1-224 view protein structure

Promoters
RGD ID:8664683
Promoter ID:EPDNEW_M10369
Type:initiation region
Name:Mesd_2
Description:Mus musculus mesoderm development LRP chaperone , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10370  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38783,892,013 - 83,892,073EPDNEW
RGD ID:8664677
Promoter ID:EPDNEW_M10370
Type:initiation region
Name:Mesd_1
Description:Mus musculus mesoderm development LRP chaperone , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10369  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38783,892,266 - 83,892,326EPDNEW
RGD ID:6840243
Promoter ID:MM_KWN:51401
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK009626_2310034P14RIK,   NM_030705,   OTTMUST00000075241
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36791,027,386 - 91,033,182 (+)MPROMDB
RGD ID:6841515
Promoter ID:MM_KWN:51402
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_023403,   OTTMUST00000075239,   OTTMUST00000075240
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36791,040,136 - 91,040,872 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1891421 AgrOrtholog
Ensembl Genes ENSMUSG00000038503 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000094215 ENTREZGENE
  ENSMUST00000094215.10 UniProtKB/Swiss-Prot
  ENSMUST00000130103.2 UniProtKB/TrEMBL
  ENSMUST00000153377.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro MESD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67943 UniProtKB/Swiss-Prot
MGD MGI:1891421 ENTREZGENE
NCBI Gene 67943 ENTREZGENE
PANTHER LRP CHAPERONE MESD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR17600 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Mesd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mesd PhenoGen
UniProt D3YVR4_MOUSE UniProtKB/TrEMBL
  F6SWV4_MOUSE UniProtKB/TrEMBL
  MESD_MOUSE UniProtKB/Swiss-Prot
  Q8C611 ENTREZGENE
  Q8CCX7 ENTREZGENE
  Q91WK8 ENTREZGENE
  Q9CVB9 ENTREZGENE
  Q9ERE7 ENTREZGENE
UniProt Secondary Q8C611 UniProtKB/Swiss-Prot
  Q8CCX7 UniProtKB/Swiss-Prot
  Q91WK8 UniProtKB/Swiss-Prot
  Q9CVB9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-06 Mesd  mesoderm development LRP chaperone  Mesdc2  mesoderm development candidate 2  Symbol and/or name change 5135510 APPROVED