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Gene: Gdf3 (growth differentiation factor 3) Mus musculus
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Symbol: Gdf3
Name: growth differentiation factor 3
Description: Predicted to have cytokine activity; protein kinase binding activity; and transforming growth factor beta receptor binding activity. Involved in several processes, including anterior/posterior axis specification; negative regulation of myoblast differentiation; and positive regulation of fat cell differentiation. Predicted to localize to the cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in Klippel-Feil syndrome and isolated microphthalmia 7. Is expressed in several structures, including brain; epiblast; and skeleton. Orthologous to human GDF3 (growth differentiation factor 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C78318; ecat9; Gdf-3; growth/differentiation factor 3; MGC123990; MGC123991; VG-1-related protein 2; Vgr-2; Vgr2
Orthologs:
Homo sapiens (human) : GDF3 (growth differentiation factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gdf3 (growth differentiation factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf3 (growth differentiation factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF3 (growth differentiation factor 3)
Canis lupus familiaris (dog) : GDF3 (growth differentiation factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf3 (growth differentiation factor 3)
Sus scrofa (pig) : GDF3 (growth differentiation factor 3)
Chlorocebus sabaeus (green monkey) : GDF3 (growth differentiation factor 3)
Heterocephalus glaber (naked mole-rat) : Gdf3 (growth differentiation factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl6122,605,403 - 122,610,087 (-)Ensembl
GRCm386122,605,403 - 122,610,087 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376122,555,421 - 122,560,089 (-)NCBIGRCm37mm9NCBIm37
MGSCv366122,571,022 - 122,575,690 (-)NCBImm8
Celera6124,400,537 - 124,405,205 (-)NCBICelera
Cytogenetic Map6 F1NCBI
cM Map657.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gdf3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557417
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.