Lhx1 (LIM homeobox protein 1) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Lhx1 (LIM homeobox protein 1) Mus musculus
Analyze
Symbol: Lhx1
Name: LIM homeobox protein 1
RGD ID: 732964
MGI Page MGI
Description: Exhibits DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; gastrulation; and regulation of transcription, DNA-templated. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including central nervous system; embryo mesoderm; genitourinary system; gut; and sensory organ. Orthologous to human LHX1 (LIM homeobox 1); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeobox protein Lim-1; Li; LIM homeo box protein 1; LIM/homeobox protein Lhx1; Lim1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391184,408,801 - 84,416,360 (-)NCBIGRCm39mm39
GRCm39 Ensembl1184,409,110 - 84,416,361 (-)Ensembl
GRCm381184,517,975 - 84,525,534 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,518,284 - 84,525,535 (-)EnsemblGRCm38mm10GRCm38
MGSCv371184,332,881 - 84,339,036 (-)NCBIGRCm37mm9NCBIm37
MGSCv361184,335,574 - 84,341,729 (-)NCBImm8
Celera1194,132,193 - 94,138,348 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure formation involved in morphogenesis  (IGI,IMP)
anatomical structure morphogenesis  (IMP)
anterior/posterior axis specification  (IGI)
anterior/posterior pattern specification  (IGI)
branching involved in ureteric bud morphogenesis  (IEP)
cell differentiation  (IMP)
cell-cell signaling  (IGI)
cellular response to fibroblast growth factor stimulus  (ISO)
cerebellar Purkinje cell differentiation  (IGI)
cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation  (IGI)
cerebellum development  (IGI)
cervix development  (IMP)
comma-shaped body morphogenesis  (IMP)
dorsal/ventral pattern formation  (IGI)
ectoderm formation  (IGI)
embryonic pattern specification  (IGI)
embryonic retina morphogenesis in camera-type eye  (IMP)
embryonic viscerocranium morphogenesis  (IMP)
endoderm development  (IMP)
endoderm formation  (IMP)
epithelium development  (IMP)
forebrain regionalization  (IGI)
gastrulation with mouth forming second  (IMP)
head development  (IGI)
horizontal cell localization  (IMP)
kidney development  (IMP)
lateral motor column neuron migration  (IMP)
mesendoderm development  (IMP)
mesonephric duct development  (ISO)
mesonephric tubule development  (ISO)
mesonephros development  (IEP)
metanephric comma-shaped body morphogenesis  (ISO)
metanephric glomerulus development  (ISO)
metanephric part of ureteric bud development  (ISO)
metanephric renal vesicle morphogenesis  (IEP)
metanephric S-shaped body morphogenesis  (IEP,ISO)
metanephros development  (IEP)
motor neuron axon guidance  (IMP)
multicellular organism development  (IEA)
negative regulation of transcription, DNA-templated  (IMP)
nephric duct elongation  (IMP)
nephric duct morphogenesis  (IMP)
nervous system development  (IEA)
neuron differentiation  (IBA)
oviduct development  (IMP)
oviduct epithelium development  (IMP)
paramesonephric duct development  (IMP)
pattern specification process  (IGI,IMP)
positive regulation of anterior head development  (IMP)
positive regulation of branching involved in ureteric bud morphogenesis  (IMP)
positive regulation of embryonic development  (IMP)
positive regulation of gastrulation  (IMP)
positive regulation of nephron tubule epithelial cell differentiation  (IMP)
positive regulation of transcription, DNA-templated  (IGI,IMP)
post-embryonic development  (IMP)
primitive streak formation  (IMP)
pronephros development  (IEP)
regulation of gene expression  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
regulation of transcription, DNA-templated  (IEA)
renal vesicle morphogenesis  (IMP)
retina development in camera-type eye  (IEP)
retina layer formation  (IEP,IMP)
S-shaped body morphogenesis  (IMP)
somite rostral/caudal axis specification  (IMP)
spinal cord association neuron differentiation  (IGI)
spinal cord development  (IEP)
telencephalon development  (IEP)
transcription by RNA polymerase II  (IDA)
ureter morphogenesis  (IGI)
ureteric bud development  (IMP)
urogenital system development  (IMP)
uterine epithelium development  (IMP)
uterus development  (IMP)
vagina development  (IMP)
ventral spinal cord development  (IEP)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal allantois morphology  (IAGP)
abnormal anterior head development  (IAGP)
abnormal axon guidance  (IAGP)
abnormal brain development  (IAGP)
abnormal brain morphology  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal diencephalon morphology  (IAGP)
abnormal egg cylinder morphology  (IAGP)
abnormal endoderm development  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal gastrulation movements  (IAGP)
abnormal heart looping  (IAGP)
abnormal heart morphology  (IAGP)
abnormal hindbrain development  (IAGP)
abnormal kidney development  (IAGP)
abnormal kidney medulla development  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal male reproductive system morphology  (IAGP)
abnormal mesonephros morphology  (IAGP)
abnormal Mullerian duct morphology  (IAGP)
abnormal nervous system development  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal primitive node morphology  (IAGP)
abnormal primitive streak elongation  (IAGP)
abnormal primitive streak formation  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal spinal cord morphology  (IAGP)
abnormal telencephalon morphology  (IAGP)
abnormal ureter development  (IAGP)
abnormal ureter morphology  (IAGP)
abnormal ureteric bud elongation  (IAGP)
abnormal ureteric bud morphology  (IAGP)
abnormal urinary bladder morphology  (IAGP)
abnormal Wolffian duct morphology  (IAGP)
absent cerebellar foliation  (IAGP)
absent epididymis  (IAGP)
absent forebrain  (IAGP)
absent kidney  (IAGP)
absent metanephros  (IAGP)
absent midbrain  (IAGP)
absent Mullerian ducts  (IAGP)
absent nephron  (IAGP)
absent ovary  (IAGP)
absent prechordal mesoderm  (IAGP)
absent Purkinje cell layer  (IAGP)
absent renal glomerulus  (IAGP)
absent testes  (IAGP)
absent ureter  (IAGP)
absent uterus  (IAGP)
absent vas deferens  (IAGP)
acephaly  (IAGP)
agonadal  (IAGP)
cardia bifida  (IAGP)
cellular necrosis  (IAGP)
decreased circulating alkaline phosphatase level  (IEA)
decreased embryo size  (IAGP)
decreased nephron number  (IAGP)
decreased Purkinje cell number  (IAGP)
decreased renal glomerulus number  (IAGP)
dilated allantois  (IAGP)
duplex kidney  (IAGP)
ectopic ureter  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic-extraembryonic boundary constriction  (IAGP)
enlarged pericardium  (IAGP)
failure of initiation of embryo turning  (IAGP)
hydronephrosis  (IAGP)
hydroureter  (IAGP)
impaired branching involved in ureteric bud morphogenesis  (IAGP)
incomplete embryo turning  (IAGP)
microcephaly  (IAGP)
Mullerian duct degeneration  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
renal hypoplasia  (IAGP)
rostral-caudal axis duplication  (IAGP)
rudimentary Mullerian ducts  (IAGP)
rudimentary Wolffian ducts  (IAGP)
single kidney  (IAGP)
small allantois  (IAGP)
small cerebellum  (IAGP)
small kidney  (IAGP)
small metanephros  (IAGP)
uterus hypoplasia  (IAGP)
Wolffian duct degeneration  (IAGP)
References

Additional References at PubMed
PMID:2907477   PMID:7700351   PMID:7904966   PMID:7909459   PMID:7909549   PMID:8069909   PMID:8069910   PMID:8543149   PMID:8565076   PMID:8565836   PMID:8756299   PMID:8793615  
PMID:8812059   PMID:8817562   PMID:8918878   PMID:8951075   PMID:9022063   PMID:9078439   PMID:9102308   PMID:9136933   PMID:9165114   PMID:9169845   PMID:9212161   PMID:9230312  
PMID:9315901   PMID:9431803   PMID:9434953   PMID:9449667   PMID:9449674   PMID:9468533   PMID:9520423   PMID:9689088   PMID:9790191   PMID:9811592   PMID:9858722   PMID:10328927  
PMID:10337615   PMID:10349636   PMID:10373301   PMID:10399918   PMID:10421635   PMID:10431240   PMID:10433919   PMID:10479450   PMID:10482234   PMID:10482235   PMID:10512182   PMID:10529411  
PMID:10529425   PMID:10588871   PMID:10662781   PMID:10668924   PMID:10688202   PMID:10693795   PMID:10704385   PMID:10706291   PMID:10741426   PMID:10748463   PMID:10751169   PMID:10804184  
PMID:10862151   PMID:10864462   PMID:10882526   PMID:10887078   PMID:10887087   PMID:10934027   PMID:10943837   PMID:11042159   PMID:11060242   PMID:11071781   PMID:11076861   PMID:11161479  
PMID:11217851   PMID:11239429   PMID:11290295   PMID:11291865   PMID:11306624   PMID:11358868   PMID:11412024   PMID:11418863   PMID:11493561   PMID:11502253   PMID:11502254   PMID:11532921  
PMID:11567052   PMID:11567614   PMID:11689706   PMID:11731460   PMID:11857795   PMID:11877374   PMID:11944941   PMID:12062038   PMID:12062039   PMID:12091315   PMID:12223418   PMID:12351192  
PMID:12381664   PMID:12435629   PMID:12435636   PMID:12447384   PMID:12466851   PMID:12467588   PMID:12471260   PMID:12477932   PMID:12490556   PMID:12530965   PMID:12581525   PMID:12588852  
PMID:12619132   PMID:12676095   PMID:12729564   PMID:12750339   PMID:12765610   PMID:12787506   PMID:12799141   PMID:12874124   PMID:12915318   PMID:12952897   PMID:12971989   PMID:12972006  
PMID:13129926   PMID:14502576   PMID:14511481   PMID:14595835   PMID:14660441   PMID:14681479   PMID:14695376   PMID:14764602   PMID:14960494   PMID:15053981   PMID:15142971   PMID:15196959  
PMID:15201223   PMID:15215210   PMID:15229603   PMID:15240886   PMID:15342483   PMID:15355796   PMID:15363391   PMID:15469980   PMID:15528197   PMID:15607939   PMID:15618518   PMID:15678491  
PMID:15691760   PMID:15733084   PMID:15753214   PMID:15769945   PMID:15857913   PMID:15870281   PMID:15901662   PMID:15917450   PMID:15922675   PMID:15930101   PMID:15930111   PMID:15976303  
PMID:16018995   PMID:16049112   PMID:16054034   PMID:16055717   PMID:16139370   PMID:16141072   PMID:16141073   PMID:16216236   PMID:16223478   PMID:16234809   PMID:16236767   PMID:16291784  
PMID:16291793   PMID:16319116   PMID:16322559   PMID:16364899   PMID:16368929   PMID:16397896   PMID:16600854   PMID:16602821   PMID:16675530   PMID:16690754   PMID:16700072   PMID:16728477  
PMID:16751104   PMID:16781703   PMID:16790474   PMID:16790481   PMID:16815997   PMID:16831833   PMID:16839541   PMID:16887818   PMID:16919269   PMID:16943278   PMID:16950123   PMID:16971467  
PMID:17036046   PMID:17075007   PMID:17075876   PMID:17086203   PMID:17122047   PMID:17123502   PMID:17127040   PMID:17133501   PMID:17150208   PMID:17166926   PMID:17219401   PMID:17229764  
PMID:17300925   PMID:17301087   PMID:17314325   PMID:17389379   PMID:17452023   PMID:17467685   PMID:17475798   PMID:17493606   PMID:17537789   PMID:17537799   PMID:17597063   PMID:17605791  
PMID:17610272   PMID:17611227   PMID:17634284   PMID:17654714   PMID:17664423   PMID:17670789   PMID:17676639   PMID:17697936   PMID:17729296   PMID:17936260   PMID:17953485   PMID:18028899  
PMID:18061570   PMID:18065432   PMID:18076286   PMID:18094027   PMID:18094249   PMID:18198335   PMID:18215620   PMID:18223201   PMID:18241853   PMID:18287559   PMID:18329011   PMID:18346943  
PMID:18358465   PMID:18367606   PMID:18380663   PMID:18395837   PMID:18403408   PMID:18463247   PMID:18498101   PMID:18522874   PMID:18554416   PMID:18617531   PMID:18625066   PMID:18662545  
PMID:18694563   PMID:18700968   PMID:18721803   PMID:18781635   PMID:18940586   PMID:18974875   PMID:19029045   PMID:19030180   PMID:19048639   PMID:19088086   PMID:19088088   PMID:19088125  
PMID:19109910   PMID:19135992   PMID:19153222   PMID:19244520   PMID:19279136   PMID:19304889   PMID:19334288   PMID:19386638   PMID:19403835   PMID:19463901   PMID:19474326   PMID:19501082  
PMID:19542352   PMID:19544582   PMID:19591821   PMID:19607821   PMID:19615442   PMID:19668217   PMID:19692620   PMID:19715689   PMID:19850875   PMID:19890917   PMID:19898483   PMID:19923199  
PMID:19924827   PMID:20004188   PMID:20035737   PMID:20040500   PMID:20059953   PMID:20211142   PMID:20346354   PMID:20375015   PMID:20400693   PMID:20417196   PMID:20436479   PMID:20460368  
PMID:20484223   PMID:20495559   PMID:20503365   PMID:20562861   PMID:20573697   PMID:20589911   PMID:20685998   PMID:20692345   PMID:20708584   PMID:20711475   PMID:20809939   PMID:20816794  
PMID:20826310   PMID:20826655   PMID:20845430   PMID:20876279   PMID:20876643   PMID:20932939   PMID:20941375   PMID:20956555   PMID:21069829   PMID:21084609   PMID:21167960   PMID:21212101  
PMID:21215373   PMID:21246650   PMID:21248112   PMID:21307096   PMID:21316586   PMID:21364975   PMID:21386911   PMID:21420949   PMID:21431469   PMID:21451052   PMID:21491542   PMID:21525287  
PMID:21554866   PMID:21558380   PMID:21569850   PMID:21664577   PMID:21674568   PMID:21677750   PMID:21693517   PMID:21698205   PMID:21731673   PMID:21731775   PMID:21752929   PMID:21802298  
PMID:21822279   PMID:21830221   PMID:21844226   PMID:21873635   PMID:21880902   PMID:21888672   PMID:21896659   PMID:21909369   PMID:21925604   PMID:21930913   PMID:21943603   PMID:21963425  
PMID:22036570   PMID:22102297   PMID:22110055   PMID:22159578   PMID:22231913   PMID:22307612   PMID:22326227   PMID:22411557   PMID:22419569   PMID:22432025   PMID:22457488   PMID:22485187  
PMID:22510988   PMID:22511595   PMID:22833130   PMID:22923088   PMID:22984579   PMID:23074133   PMID:23193182   PMID:23197712   PMID:23201013   PMID:23223288   PMID:23283339   PMID:23284619  
PMID:23307637   PMID:23362348   PMID:23362349   PMID:23418536   PMID:23459943   PMID:23469192   PMID:23471918   PMID:23482494   PMID:23521771   PMID:23555292   PMID:23595746   PMID:23648511  
PMID:23651855   PMID:23652001   PMID:23669529   PMID:23724000   PMID:23747598   PMID:23760955   PMID:23762375   PMID:23805044   PMID:23920117   PMID:23926259   PMID:24007338   PMID:24146773  
PMID:24198374   PMID:24210661   PMID:24335253   PMID:24360544   PMID:24370450   PMID:24440154   PMID:24453340   PMID:24463367   PMID:24491816   PMID:24550112   PMID:24560999   PMID:24594479  
PMID:24598167   PMID:24715462   PMID:24767996   PMID:24917498   PMID:24924197   PMID:24952961   PMID:25035422   PMID:25108913   PMID:25139858   PMID:25142465   PMID:25176648   PMID:25179941  
PMID:25228773   PMID:25231759   PMID:25313862   PMID:25369423   PMID:25617721   PMID:25641696   PMID:25673830   PMID:25794677   PMID:25834049   PMID:25868900   PMID:25888505   PMID:25896202  
PMID:25910836   PMID:25943695   PMID:25966682   PMID:25977363   PMID:25993409   PMID:26047795   PMID:26164566   PMID:26257176   PMID:26335645   PMID:26444681   PMID:26494787   PMID:26520399  
PMID:26527010   PMID:26628093   PMID:26633881   PMID:26658320   PMID:26758845   PMID:26937009   PMID:27469598   PMID:27568519   PMID:27633993   PMID:27649575   PMID:27760115   PMID:27770010  
PMID:27820600   PMID:28011038   PMID:28017605   PMID:28082864   PMID:28165338   PMID:28516904   PMID:28603487   PMID:28705898   PMID:28760814   PMID:28839193   PMID:28850031   PMID:29113990  
PMID:29129523   PMID:29168693   PMID:29363583   PMID:29394901   PMID:29439133   PMID:29449451   PMID:29679559   PMID:29712641   PMID:29795232   PMID:29874580   PMID:29912395   PMID:29922981  
PMID:29945868   PMID:30063881   PMID:30114334   PMID:30127719   PMID:30338292   PMID:30406191   PMID:30456369   PMID:30620636   PMID:30635555   PMID:30959515   PMID:31152445   PMID:31305241  
PMID:31488566   PMID:31705443   PMID:31772170   PMID:31869353   PMID:31923383   PMID:31950080   PMID:32071204   PMID:32141129   PMID:32187534   PMID:32439762   PMID:32541007   PMID:32554463  
PMID:32868762   PMID:32878923  


Genomics

Comparative Map Data
Lhx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391184,408,801 - 84,416,360 (-)NCBIGRCm39mm39
GRCm39 Ensembl1184,409,110 - 84,416,361 (-)Ensembl
GRCm381184,517,975 - 84,525,534 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,518,284 - 84,525,535 (-)EnsemblGRCm38mm10GRCm38
MGSCv371184,332,881 - 84,339,036 (-)NCBIGRCm37mm9NCBIm37
MGSCv361184,335,574 - 84,341,729 (-)NCBImm8
Celera1194,132,193 - 94,138,348 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.31NCBI
LHX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1736,936,785 - 36,944,612 (+)EnsemblGRCh38hg38GRCh38
GRCh381736,937,475 - 36,944,612 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371735,294,772 - 35,301,912 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361732,368,612 - 32,374,607 (+)NCBINCBI36hg18NCBI36
Build 341732,368,611 - 32,374,607NCBI
Celera1732,116,628 - 32,122,623 (+)NCBI
Cytogenetic Map17q12NCBI
HuRef1731,230,715 - 31,237,858 (+)NCBIHuRef
CHM1_11735,329,038 - 35,336,178 (+)NCBICHM1_1
Lhx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21069,396,829 - 69,403,617 (-)NCBI
Rnor_6.0 Ensembl1071,843,991 - 71,849,293 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01071,843,991 - 71,849,293 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01071,752,917 - 71,758,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41072,800,497 - 72,805,799 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11072,814,866 - 72,820,169 (-)NCBI
Celera1068,324,814 - 68,330,116 (-)NCBICelera
Cytogenetic Map10q26NCBI
Lhx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554511,037,825 - 1,048,501 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554511,037,936 - 1,048,501 (-)NCBIChiLan1.0ChiLan1.0
LHX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11720,430,618 - 20,437,751 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1720,430,618 - 20,437,751 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01720,134,308 - 20,140,652 (-)NCBIMhudiblu_PPA_v0panPan3
LHX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1936,760,890 - 36,768,345 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl936,761,826 - 36,768,164 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha935,986,818 - 35,993,342 (+)NCBI
ROS_Cfam_1.0937,571,199 - 37,577,732 (+)NCBI
UMICH_Zoey_3.1936,353,003 - 36,359,535 (+)NCBI
UNSW_CanFamBas_1.0936,640,659 - 36,647,196 (+)NCBI
UU_Cfam_GSD_1.0936,727,884 - 36,734,417 (+)NCBI
Lhx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560235,742,907 - 35,750,671 (+)NCBI
SpeTri2.0NW_0049364901,324,378 - 1,332,177 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LHX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1238,450,708 - 38,456,139 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11238,450,708 - 38,457,583 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21240,067,286 - 40,073,812 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LHX1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11630,843,062 - 30,850,182 (-)NCBI
ChlSab1.1 Ensembl1630,842,652 - 30,849,465 (-)Ensembl
Lhx1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248713,954,490 - 3,961,861 (+)NCBI

Position Markers
Lhx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11CUniSTS
cM Map1148.0UniSTS
cM Map1148.0UniSTS
Z27410  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381184,519,383 - 84,519,462UniSTSGRCm38
MGSCv371184,332,885 - 84,332,964UniSTSGRCm37
Celera1194,132,197 - 94,132,276UniSTS
Cytogenetic Map11CUniSTS
cM Map1148.0UniSTS
Whitehead/MRC_RH111059.1UniSTS
Whitehead_YAC11 UniSTS
Lhx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11CUniSTS
cM Map1148.0UniSTS
Lhx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11CUniSTS
cM Map1148.0UniSTS
Z27410  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381184,519,386 - 84,519,526UniSTSGRCm38
MGSCv371184,332,888 - 84,333,028UniSTSGRCm37
Celera1194,132,200 - 94,132,340UniSTS
Cytogenetic Map11CUniSTS
Whitehead/MRC_RH111059.1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179922933104611872Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1181000000102000000Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1227
Count of miRNA genes:592
Interacting mature miRNAs:773
Transcripts:ENSMUST00000018842, ENSMUST00000092827, ENSMUST00000176503, ENSMUST00000184646
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000018842   ⟹   ENSMUSP00000018842
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1184,518,284 - 84,525,535 (-)Ensembl
RefSeq Acc Id: ENSMUST00000092827   ⟹   ENSMUSP00000090503
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1184,521,896 - 84,522,711 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176503
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1184,519,706 - 84,522,067 (-)Ensembl
RefSeq Acc Id: ENSMUST00000184646   ⟹   ENSMUSP00000138899
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1184,519,442 - 84,522,331 (-)Ensembl
RefSeq Acc Id: NM_008498   ⟹   NP_032524
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391184,408,801 - 84,416,360 (-)NCBI
GRCm381184,517,975 - 84,525,534 (-)NCBI
MGSCv371184,332,881 - 84,339,036 (-)RGD
Celera1194,132,193 - 94,138,348 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032524   ⟸   NM_008498
- UniProtKB: P63006 (UniProtKB/Swiss-Prot),   Q569N5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000138899   ⟸   ENSMUST00000184646
RefSeq Acc Id: ENSMUSP00000090503   ⟸   ENSMUST00000092827
RefSeq Acc Id: ENSMUSP00000018842   ⟸   ENSMUST00000018842
Protein Domains
Homeobox   LIM zinc-binding

Promoters
RGD ID:6821176
Promoter ID:MM_KWN:8950
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney
Transcripts:ENSMUST00000092827,   ENSMUST00000108082
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361184,336,051 - 84,336,551 (-)MPROMDB
RGD ID:6821198
Promoter ID:MM_KWN:8951
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:ENSMUST00000018842,   LINCRNA_175,   OTTMUST00000001917,   OTTMUST00000001918,   OTTMUST00000001919
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361184,338,754 - 84,339,254 (+)MPROMDB
RGD ID:8675956
Promoter ID:EPDNEW_M16009
Type:multiple initiation site
Name:Lhx1_1
Description:Mus musculus LIM homeobox protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381184,525,534 - 84,525,594EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99783 AgrOrtholog
Ensembl Genes ENSMUSG00000018698 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000018842 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000090503 UniProtKB/TrEMBL
  ENSMUSP00000138899 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000018842 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000092827 UniProtKB/TrEMBL
  ENSMUST00000184646 UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16869 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:99783 ENTREZGENE
NCBI Gene 16869 ENTREZGENE
Pfam Homeodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lhx1 PhenoGen
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WNK8_MOUSE UniProtKB/TrEMBL
  A0A0A0MQA9_MOUSE UniProtKB/TrEMBL
  LHX1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3URX6_MOUSE UniProtKB/TrEMBL
  Q569N5 ENTREZGENE, UniProtKB/TrEMBL
  Q8BNR0_MOUSE UniProtKB/TrEMBL
  Q8CCU9_MOUSE UniProtKB/TrEMBL
UniProt Secondary P36199 UniProtKB/Swiss-Prot