Mrps25 (mitochondrial ribosomal protein S25) - Rat Genome Database
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Gene: Mrps25 (mitochondrial ribosomal protein S25) Mus musculus
Analyze
Symbol: Mrps25
Name: mitochondrial ribosomal protein S25
RGD ID: 1318738
MGI Page MGI
Description: Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 50. Orthologous to human MRPS25 (mitochondrial ribosomal protein S25); INTERACTS WITH 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810429N01Rik; 28S ribosomal protein S25, mitochondrial; MRP-S25; Rpm; Rpms25; S25mt
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39692,146,493 - 92,161,004 (-)NCBIGRCm39mm39
GRCm39 Ensembl692,146,506 - 92,161,014 (-)Ensembl
GRCm38692,169,512 - 92,184,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl692,169,525 - 92,184,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv37692,119,506 - 92,134,017 (-)NCBIGRCm37mm9NCBIm37
MGSCv36692,135,016 - 92,149,527 (-)NCBImm8
Celera694,065,055 - 94,079,564 (-)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:10938081   PMID:11023686   PMID:11042159   PMID:11076861   PMID:11812828   PMID:12477932   PMID:14610273   PMID:15449545   PMID:15489334  
PMID:16141072   PMID:16141073   PMID:18287559   PMID:18614015   PMID:21873635   PMID:24194600   PMID:27626380   PMID:28700664   PMID:32098917   PMID:32376682   PMID:32987154  


Genomics

Comparative Map Data
Mrps25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39692,146,493 - 92,161,004 (-)NCBIGRCm39mm39
GRCm39 Ensembl692,146,506 - 92,161,014 (-)Ensembl
GRCm38692,169,512 - 92,184,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl692,169,525 - 92,184,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv37692,119,506 - 92,134,017 (-)NCBIGRCm37mm9NCBIm37
MGSCv36692,135,016 - 92,149,527 (-)NCBImm8
Celera694,065,055 - 94,079,564 (-)NCBICelera
Cytogenetic Map6D1NCBI
MRPS25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl315,042,460 - 15,065,317 (-)EnsemblGRCh38hg38GRCh38
GRCh38315,042,251 - 15,065,315 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37315,083,758 - 15,106,822 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36315,065,023 - 15,081,820 (-)NCBINCBI36hg18NCBI36
Build 34315,065,023 - 15,081,820NCBI
Celera315,028,290 - 15,045,083 (-)NCBI
Cytogenetic Map3p25.1NCBI
HuRef315,025,627 - 15,042,423 (-)NCBIHuRef
CHM1_1315,034,709 - 15,057,793 (-)NCBICHM1_1
Mrps25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24124,668,320 - 124,680,086 (-)NCBI
Rnor_6.0 Ensembl4124,036,655 - 124,048,417 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04124,036,654 - 124,048,417 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04189,213,384 - 189,225,147 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,351,113 - 126,362,876 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14126,595,954 - 126,607,717 (-)NCBI
Celera4113,586,158 - 113,597,921 (-)NCBICelera
Cytogenetic Map4q34NCBI
Mrps25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542917,432,443 - 17,436,247 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542917,424,570 - 17,436,247 (-)NCBIChiLan1.0ChiLan1.0
MRPS25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1315,305,642 - 15,328,594 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl315,313,061 - 15,328,594 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0314,934,006 - 14,989,899 (-)NCBIMhudiblu_PPA_v0panPan3
MRPS25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl205,141,812 - 5,152,513 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1205,141,812 - 5,152,507 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Mrps25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936602559,127 - 584,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPS25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1369,441,116 - 69,467,895 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11369,441,100 - 69,465,912 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21376,734,137 - 76,739,069 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MRPS25
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12250,985,398 - 50,997,596 (-)NCBI
ChlSab1.1 Ensembl2250,984,775 - 50,997,581 (-)Ensembl
Mrps25
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624872948,073 - 950,899 (+)NCBI

Position Markers
RH136860  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38692,174,888 - 92,175,076UniSTSGRCm38
MGSCv37692,124,882 - 92,125,070UniSTSGRCm37
Celera694,070,431 - 94,070,619UniSTS
Cytogenetic Map6D3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690795610124795846Mouse
1301534Idd20_minsulin dependent diabetes susceptibility 20 (mouse)Not determined69203995092716697Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1942
Count of miRNA genes:822
Interacting mature miRNAs:1072
Transcripts:ENSMUST00000014695, ENSMUST00000134132, ENSMUST00000140438
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000014695
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl692,174,838 - 92,175,902 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134132
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl692,178,313 - 92,183,971 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140438   ⟹   ENSMUSP00000114402
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl692,169,525 - 92,184,033 (-)Ensembl
RefSeq Acc Id: NM_025578   ⟹   NP_079854
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39692,146,493 - 92,161,004 (-)NCBI
GRCm38692,169,512 - 92,184,023 (-)ENTREZGENE
MGSCv37692,119,506 - 92,134,017 (-)RGD
Celera694,065,055 - 94,079,564 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_079854   ⟸   NM_025578
- UniProtKB: Q9D125 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000114402   ⟸   ENSMUST00000140438
Protein Domains
L51_S25_CI-B8

Promoters
RGD ID:6839660
Promoter ID:MM_KWN:46947
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver,   Lung,   MEF_B6
Transcripts:OTTMUST00000058666
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36692,125,351 - 92,125,851 (-)MPROMDB
RGD ID:6839659
Promoter ID:MM_KWN:46948
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000058664,   OTTMUST00000058665
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36692,133,704 - 92,134,204 (-)MPROMDB
RGD ID:6890470
Promoter ID:EPDNEW_M8686
Type:initiation region
Name:Mrps25_1
Description:Mus musculus mitochondrial ribosomal protein S25 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38692,183,991 - 92,184,051EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1928140 AgrOrtholog
Ensembl Genes ENSMUSG00000014551 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000114402 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000140438 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro MRPS25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosome/NADH_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:64658 UniProtKB/Swiss-Prot
MGD MGI:1928140 ENTREZGENE
NCBI Gene 64658 ENTREZGENE
PANTHER PTHR13274 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam L51_S25_CI-B8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mrps25 PhenoGen
SMART L51_S25_CI-B8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q6KAU3_MOUSE UniProtKB/TrEMBL
  Q9D125 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9CYY8 UniProtKB/Swiss-Prot