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ONTOLOGY REPORT - ANNOTATIONS

Term:myelin sheath
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Accession:GO:0043209 term browser browse the term
Definition:An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
Synonyms:narrow_synonym: Schwann cell myelin sheath;   astrocyte sheath;   oligodendrocyte myelin sheath
 xref: FMA:62983;   NIF_Subcellular:sao593830697;   Wikipedia:Myelin
 only_in_taxon: NCBITaxon:33208 ! Metazoa


show annotations for term's descendants           Sort by:
myelin sheath term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07013776.1 located_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr 2:239,898,492...239,898,935 JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 located_in IDA PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Bcl2 BCL2, apoptosis regulator located_in IEA
ISO		 GO_REF:0000107
(PMID:7953633)		 Ensembl
RGD		 PMID:7953633 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Calm1 calmodulin 1 located_in
is_active_in		 IDA
IBA
ISO
IEA		 PMID:19855925
GO_REF:0000033
(PMID:19855925)
GO_REF:0000117		 GO_Central
RGD
UniProt		 PMID:19855925 PMID:19855925 GO_REF:0000033 GO_REF:0000117, RGD:12793026 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 located_in
is_active_in		 IDA
IBA
ISO
IEA		 PMID:19855925
GO_REF:0000033
(PMID:19855925)
GO_REF:0000117		 GO_Central
RGD
UniProt		 PMID:19855925 PMID:19855925 GO_REF:0000033 GO_REF:0000117, RGD:12793026 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calm3 calmodulin 3 located_in
is_active_in		 IDA
IBA
ISO
IEA		 PMID:19855925
GO_REF:0000033
(PMID:19855925)
GO_REF:0000117		 GO_Central
RGD
UniProt		 PMID:19855925 PMID:19855925 GO_REF:0000033 GO_REF:0000117, RGD:12793026 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Calml3 calmodulin-like 3 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175 		JBrowse link
G Car13 carbonic anhydrase 13 located_in ISO (PMID:14600151) RGD PMID:14600151 NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525 		JBrowse link
G Car2 carbonic anhydrase 2 located_in ISO (PMID:14600151) RGD PMID:14600151 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Clcn2 chloride voltage-gated channel 2 located_in ISO (PMID:22405205)
(PMID:17567819)		 RGD PMID:17567819 PMID:22405205 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase located_in IDA
ISO		 PMID:17960831
(PMID:24101522), (PMID:28251676)		 RGD PMID:24101522 PMID:28251676 PMID:17960831 RGD:10047364 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Cntn2 contactin 2 located_in IEA
ISO		 GO_REF:0000107
(PMID:12963709)		 Ensembl
RGD		 PMID:12963709 GO_REF:0000107 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 located_in IDA PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 located_in IEA
ISO		 GO_REF:0000107
(PMID:15044753)		 Ensembl
RGD		 PMID:15044753 GO_REF:0000107 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ermn ermin is_active_in
located_in		 IBA
ISO		 GO_REF:0000033
(PMID:16421295)		 GO_Central
RGD		 PMID:16421295 GO_REF:0000033 NCBI chr 3:42,628,160...42,633,816
Ensembl chr 3:42,626,309...42,633,744 		JBrowse link
G Gdi1 GDP dissociation inhibitor 1 located_in IDA PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chr  X:152,087,611...152,094,274
Ensembl chr  X:152,087,444...152,094,272 		JBrowse link
G Gjc2 gap junction protein, gamma 2 located_in ISO (PMID:20578039) RGD PMID:20578039 NCBI chr10:43,962,642...43,971,358
Ensembl chr10:43,962,642...43,970,467 		JBrowse link
G Gjc3 gap junction protein, gamma 3 located_in ISO (PMID:16481432) RGD PMID:16481432 NCBI chr12:16,899,846...16,912,309
Ensembl chr12:16,896,813...16,964,246 		JBrowse link
G Glul glutamate-ammonia ligase located_in IDA PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gnao1 G protein subunit alpha o1 located_in IDA PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gpm6b glycoprotein m6b is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211 		JBrowse link
G Gsn gelsolin located_in IDA PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 located_in
is_active_in		 IDA
IBA		 PMID:17960831
GO_REF:0000033		 GO_Central PMID:17960831 GO_REF:0000033, RGD:10047364 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Mag myelin-associated glycoprotein located_in ISO (PMID:6200494)
(PMID:11283023), (PMID:24101522)		 RGD PMID:6200494 PMID:11283023 PMID:24101522 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Mbp myelin basic protein located_in IDA
ISO
IEA		 PMID:19855925
(PMID:16405874), (PMID:16421295), (PMID:1694232), (PMID:19855925), (PMID:20578039), (PMID:24101522), (PMID:29034508)
(PMID:19855925)
GO_REF:0000044
PMID:17960831		 RGD
UniProt		 PMID:1694232 PMID:16405874 PMID:16421295 PMID:19855925 PMID:20578039 More... GO_REF:0000044, RGD:12793026, RGD:10047364 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Myo1d myosin ID located_in ISS
ISO
IEA
IDA		 GO_REF:0000024
(PMID:22284616)
GO_REF:0000107
PMID:17960831		 UniProt
RGD
Ensembl		 PMID:22284616 PMID:17960831 GO_REF:0000024 GO_REF:0000107, RGD:10047364 NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349 		JBrowse link
G Plec plectin located_in
is_active_in		 IEA
ISO		 GO_REF:0000107
(PMID:19625254)		 Ensembl
RGD		 PMID:19625254 GO_REF:0000107 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Pllp plasmolipin located_in ISO (PMID:26002055) RGD PMID:26002055 NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892 		JBrowse link
G Plp1 proteolipid protein 1 located_in
is_active_in		 IDA
ISO
IBA		 PMID:17960831
(PMID:1694232), (PMID:20578039)
GO_REF:0000033		 RGD
GO_Central		 PMID:1694232 PMID:20578039 PMID:17960831 GO_REF:0000033, RGD:10047364 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Pmp2 peripheral myelin protein 2 located_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:91,611,334...91,615,252
Ensembl chr 2:91,611,334...91,615,252 		JBrowse link
G Prxl2b peroxiredoxin like 2B located_in IDA
ISO		 PMID:20950588
(PMID:20950588)		 RGD PMID:20950588 PMID:20950588 RGD:8554513 NCBI chr 5:165,462,610...165,465,213 JBrowse link
G Septin8 septin 8 located_in IDA PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chr10:37,684,649...37,713,704
Ensembl chr10:37,684,639...37,713,174 		JBrowse link
G Serinc5 serine incorporator 5 located_in IEA
ISO		 GO_REF:0000107
(PMID:16405874)		 Ensembl
RGD		 PMID:16405874 GO_REF:0000107 NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346 		JBrowse link
G Sirt2 sirtuin 2 located_in ISS
ISO
IEA
IDA		 GO_REF:0000024
(PMID:16933150)
GO_REF:0000044
PMID:17960831
PMID:17344398		 UniProt
RGD		 PMID:16933150 PMID:17960831 PMID:17344398 GO_REF:0000024 GO_REF:0000044, RGD:10047364, RGD:8553877 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Tspan2 tetraspanin 2 located_in ISO (PMID:24038504) RGD PMID:24038504 NCBI chr 2:190,177,717...190,234,994
Ensembl chr 2:190,177,741...190,219,660 		JBrowse link
G Tuba1a tubulin, alpha 1A located_in IDA PMID:17960831 UniProt PMID:17960831 RGD:10047364 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tubb4a tubulin, beta 4A class IVa located_in ISO (PMID:16421295) RGD PMID:16421295 NCBI chr 9:1,917,841...1,925,286
Ensembl chr 9:1,917,845...1,925,291 		JBrowse link
compact myelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59b CD59b molecule IDA RGD PMID:12153479 RGD:625622 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Mag myelin-associated glycoprotein located_in ISO (PMID:6200494) RGD PMID:6200494 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Mbp myelin basic protein located_in
is_active_in		 IDA
ISO
IBA		 (PMID:12718855)
GO_REF:0000033
MMO:0000679		 RGD
GO_Central		 PMID:12718855 PMID:2462020 PMID:10537049 GO_REF:0000033, RGD:1358774, RGD:633193 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Pllp plasmolipin IDA RGD PMID:12871592 RGD:1358791 NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892 		JBrowse link
G Pmp22 peripheral myelin protein 22 located_in IDA
ISO		 (PMID:11114256), (PMID:29315582) RGD PMID:11114256 PMID:29315582 PMID:1556154 RGD:1358785 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
lateral loop term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 located_in IEA
ISO		 GO_REF:0000107
(PMID:20237282)		 Ensembl
RGD		 PMID:20237282 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IDA RGD PMID:15800203 RGD:1582139 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 6:97,548,133...97,654,163
Ensembl chr 6:97,548,630...97,653,305 		JBrowse link
G Pard3 par-3 family cell polarity regulator located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778 		JBrowse link
G Sirt2 sirtuin 2 located_in IDA PMID:21949390 UniProt PMID:21949390 RGD:8655533 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Stx4 syntaxin 4 located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
myelin sheath abaxonal region term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IDA RGD PMID:16051705 RGD:6483360 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 located_in IEA
ISO		 GO_REF:0000107
(PMID:20237282)		 Ensembl
RGD		 PMID:20237282 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Exoc4 exocyst complex component 4 located_in IEA
ISO		 GO_REF:0000107
(PMID:20237282)		 Ensembl
RGD		 PMID:20237282 GO_REF:0000107 NCBI chr 4:61,807,706...62,584,316
Ensembl chr 4:61,807,761...62,585,723 		JBrowse link
G Itgb1 integrin subunit beta 1 located_in IEA
ISO		 GO_REF:0000107
(PMID:20237282)		 Ensembl
RGD		 PMID:20237282 GO_REF:0000107 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Llgl1 LLGL scribble cell polarity complex component 1 located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr10:45,379,423...45,394,096
Ensembl chr10:45,379,515...45,394,094 		JBrowse link
G Myoc myocilin IDA RGD PMID:12838505 RGD:1600847 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Prkcz protein kinase C, zeta located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Scrib scribble planar cell polarity protein located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
G Sirt2 sirtuin 2 IDA RGD PMID:17344398 RGD:8553877 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
myelin sheath adaxonal region term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 located_in IEA
ISO		 GO_REF:0000107
(PMID:20237282)		 Ensembl
RGD		 PMID:20237282 GO_REF:0000107 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IDA RGD PMID:16051705 RGD:6483360 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Mag myelin-associated glycoprotein located_in IDA
ISO		 (PMID:12718855) RGD PMID:12718855 PMID:375239 RGD:9685298 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 6:97,548,133...97,654,163
Ensembl chr 6:97,548,630...97,653,305 		JBrowse link
G Pten phosphatase and tensin homolog located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Stx4 syntaxin 4 located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
Schmidt-Lanterman incisure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 IDA RGD PMID:1650113 RGD:8548783 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Anxa2 annexin A2 located_in IEA
ISO		 GO_REF:0000107
(PMID:20237282)		 Ensembl
RGD		 PMID:20237282 GO_REF:0000107 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Cdh1 cadherin 1 located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cldn19 claudin 19 located_in IEA
ISO		 GO_REF:0000107
(PMID:15883201)		 Ensembl
RGD		 PMID:15883201 GO_REF:0000107 NCBI chr 5:132,862,939...132,870,364
Ensembl chr 5:132,863,267...132,868,227 		JBrowse link
G Cldn5 claudin 5 IDA RGD PMID:12403818 RGD:634852 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Jam3 junctional adhesion molecule 3 located_in ISO (PMID:21097846) RGD PMID:21097846 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355 		JBrowse link
G Mag myelin-associated glycoprotein located_in IDA
ISO		 (PMID:12975355) RGD PMID:12975355 PMID:12838505 RGD:1600847 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Mal mal, T-cell differentiation protein IDA RGD PMID:12153479 RGD:625622 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Marveld2 MARVEL domain containing 2 located_in ISO (PMID:21097846) RGD PMID:21097846 NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 5:95,766,112...95,920,531
Ensembl chr 5:95,766,118...95,920,499 		JBrowse link
G Myoc myocilin IDA RGD PMID:12838505 RGD:1600847 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Ncmap noncompact myelin associated protein located_in
is_active_in		 IEA
IDA
IBA		 GO_REF:0000002
PMID:18650334
GO_REF:0000033		 InterPro
GO_Central		 PMID:18650334 GO_REF:0000002 GO_REF:0000033, RGD:8554263 NCBI chr 5:147,608,042...147,623,266
Ensembl chr 5:147,610,677...147,618,775 		JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 6:97,548,133...97,654,163
Ensembl chr 6:97,548,630...97,653,305 		JBrowse link
G Pard3 par-3 family cell polarity regulator located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778 		JBrowse link
G Prkci protein kinase C, iota located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352 		JBrowse link
G Pten phosphatase and tensin homolog located_in ISO (PMID:20237282) RGD PMID:20237282 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Sirt2 sirtuin 2 located_in IDA
ISS
IEA
ISO		 PMID:21949390
GO_REF:0000024
GO_REF:0000107
(PMID:16933150)		 UniProt
Ensembl
RGD		 PMID:16933150 PMID:21949390 GO_REF:0000024 GO_REF:0000107, RGD:8655533 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
Term paths to the root
Path 1
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  cellular_component 20829
    cellular anatomical structure 20629
      myelin sheath 61
        compact myelin + 21
        lateral loop 7
        myelin sheath abaxonal region 9
        myelin sheath adaxonal region 6
paths to the root