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ONTOLOGY REPORT - ANNOTATIONS

Term:protein processing
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Accession:GO:0016485 term browser browse the term
Definition:Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
Synonyms:exact_synonym: protein maturation by peptide bond cleavage;   protein maturation by peptide bond hydrolysis
 related_synonym: peptidolysis during protein maturation;   protein maturation by proteolysis
 alt_id: GO:0051605


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protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTMAP actin maturation protease involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:37,785,116...37,794,864
Ensembl chr19:46,292,232...46,302,127 		JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20383322) Ensembl
MGI		 PMID:20383322 GO_REF:0000107 NCBI chr15:37,562,930...37,717,175
Ensembl chr15:55,873,606...56,027,188 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054 		JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:152,839,326...152,972,741
Ensembl chr 5:159,494,786...159,593,171 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:12054541) ARUK-UCL PMID:12054541 NCBI chr 8:38,298,194...38,406,706
Ensembl chr 8:35,473,278...35,581,192 		JBrowse link
G ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16556917) Ensembl
MGI		 PMID:16556917 GO_REF:0000107 NCBI chr 5:174,264,811...174,502,817
Ensembl chr 5:181,557,928...181,786,175 		JBrowse link
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16556917) Ensembl
MGI		 PMID:16556917 GO_REF:0000107 NCBI chr 4:51,648,293...51,941,329
Ensembl chr 4:57,966,197...58,259,404 		JBrowse link
G AEBP1 AE binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:44,818,620...44,828,914
Ensembl chr 7:44,886,238...44,896,194 		JBrowse link
G AFG3L2 AFG3 like matrix AAA peptidase subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:1,951,279...1,999,313
Ensembl chr18:17,062,250...17,109,400 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane ISO RGD PMID:16537183 RGD:1581649 NCBI chr15:68,479,349...68,509,238
Ensembl chr15:87,681,826...87,703,713 		JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit involved_in IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:125,610,649...125,614,261
Ensembl chr 1:129,262,002...129,265,810 		JBrowse link
G APH1B aph-1 homolog B, gamma-secretase subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12297508) MGI
UniProt
Ensembl
InterPro		 PMID:12297508 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr15:42,224,593...42,256,202
Ensembl chr15:60,520,031...60,551,599 		JBrowse link
G ASPRV1 aspartic peptidase retroviral like 1 involved_in ISO (PMID:16098038)
(PMID:16837463)		 UniProt PMID:16098038 PMID:16837463 NCBI chr2A:70,008,862...70,198,244
Ensembl chr2A:71,120,541...71,121,572 		JBrowse link
G ATG4A autophagy related 4A cysteine peptidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:97,189,556...97,253,371
Ensembl chr  X:107,559,639...107,623,389 		JBrowse link
G ATG4B autophagy related 4B cysteine peptidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:128,913,323...128,950,112
Ensembl chr2B:247,702,880...247,738,977 		JBrowse link
G ATG4C autophagy related 4C cysteine peptidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:62,041,948...62,123,866
Ensembl chr 1:63,856,511...63,937,514 		JBrowse link
G ATG4D autophagy related 4D cysteine peptidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:10,095,768...10,105,250
Ensembl chr19:10,758,544...10,767,712 		JBrowse link
G BACE1 beta-secretase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:112,120,950...112,151,505
Ensembl chr11:116,054,303...116,084,812 		JBrowse link
G BACE2 beta-secretase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:27,500,453...27,612,795
Ensembl chr21:40,831,203...40,938,280 		JBrowse link
G BMP1 bone morphogenetic protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:21,410,139...21,457,144
Ensembl chr 8:18,349,836...18,396,796 		JBrowse link
G C2CD3 C2 domain containing 3 centriole elongation regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19004860) Ensembl
MGI		 PMID:19004860 GO_REF:0000107 NCBI chr11:69,085,434...69,244,791 JBrowse link
G CASP1 caspase 1 acts_upstream_of_or_within ISO (PMID:11016935), (PMID:15190255)
(PMID:16301672)
(PMID:14663141)		 MGI PMID:11016935 PMID:14663141 PMID:15190255 PMID:16301672 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CASP2 caspase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:135,283,072...135,307,855
Ensembl chr 7:147,773,749...147,792,958 		JBrowse link
G CASP3 caspase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15231831) Ensembl
MGI		 PMID:15231831 GO_REF:0000107 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G CASP7 caspase 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15231831) Ensembl
MGI		 PMID:15231831 GO_REF:0000107 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626 		JBrowse link
G CASP8 caspase 8 involved_in ISO (PMID:30361383) RGD
UniProt		 PMID:16493077 PMID:30361383 RGD:4143200 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468 		JBrowse link
G CASP9 caspase 9 ISO RGD PMID:18316105 RGD:2311460 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266 		JBrowse link
G CMA1 chymase 1 ISO RGD PMID:15869764 RGD:1581745 NCBI chr14:5,277,269...5,280,335
Ensembl chr14:23,400,345...23,403,548 		JBrowse link
G CNTN2 contactin 2 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:18278038) MGI
Ensembl		 PMID:18278038 GO_REF:0000107 NCBI chr 1:180,645,259...180,680,081
Ensembl chr 1:184,931,497...184,966,482 		JBrowse link
G COMP cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26045608) Ensembl
MGI		 PMID:26045608 GO_REF:0000107 NCBI chr19:18,222,270...18,230,936
Ensembl chr19:19,229,562...19,238,008 		JBrowse link
G CPD carboxypeptidase D involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:26,302,112...26,389,049
Ensembl chr17:26,821,641...26,908,257 		JBrowse link
G CPE carboxypeptidase E involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:2822027 GO_REF:0000118 RGD:1626225 NCBI chr 4:157,575,157...157,705,173
Ensembl chr 4:169,659,007...169,780,739 		JBrowse link
G CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29038301) Ensembl
MGI		 PMID:29038301 GO_REF:0000107 NCBI chr 1:15,368,318...15,373,815
Ensembl chr 1:16,362,655...16,368,063 		JBrowse link
G CPM carboxypeptidase M involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:66,367,023...66,445,801
Ensembl chr12:69,147,579...69,225,283 		JBrowse link
G CPN1 carboxypeptidase N subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:96,647,273...96,689,346
Ensembl chr10:100,130,688...100,171,687 		JBrowse link
G CPZ carboxypeptidase Z involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 4:8,656,029...8,684,722 JBrowse link
G CTSG cathepsin G involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:5,342,517...5,345,218
Ensembl chr14:23,466,265...23,468,960 		JBrowse link
G CTSS cathepsin S involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:126,084,249...126,118,221
Ensembl chr 1:129,733,996...129,768,318 		JBrowse link
G DDI2 DNA damage inducible 1 homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:14,757,327...14,810,959
Ensembl chr 1:15,749,497...15,790,263
Ensembl chr 1:15,749,497...15,790,263 		JBrowse link
G DYNC2H1 dynein cytoplasmic 2 heavy chain 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16229832)
(PMID:16061793)		 Ensembl
MGI		 PMID:16061793 PMID:16229832 GO_REF:0000107 NCBI chr11:98,051,788...98,425,676
Ensembl chr11:101,536,471...101,909,194 		JBrowse link
G ECE1 endothelin converting enzyme 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:8034569 GO_REF:0000107 RGD:728596 NCBI chr 1:20,166,019...20,290,803
Ensembl chr 1:21,206,199...21,278,909 		JBrowse link
G ECE2 endothelin converting enzyme 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:181,310,554...181,327,602
Ensembl chr 3:189,766,786...189,811,206 		JBrowse link
G ENPEP glutamyl aminopeptidase ISO RGD PMID:16537183 RGD:1581649 NCBI chr 4:102,969,397...103,056,978
Ensembl chr 4:113,532,126...113,620,654 		JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F3 coagulation factor III, tissue factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F7 coagulation factor VII involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G FKRP fukutin related protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12471058) Ensembl
MGI		 PMID:12471058 GO_REF:0000107 NCBI chr19:43,738,339...43,748,250
Ensembl chr19:52,273,546...52,276,341 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21147780), (PMID:23918928)
(PMID:20530870)
(PMID:15606899)		 RGD
MGI
Ensembl		 PMID:11861638 PMID:15194465 PMID:15606899 PMID:20530870 PMID:21147780 More... GO_REF:0000107 RGD:1582619 RGD:633598 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023 		JBrowse link
G GLG1 golgi glycoprotein 1 acts_upstream_of ISO (PMID:20530870) MGI PMID:20530870 NCBI chr16:55,014,892...55,172,877
Ensembl chr16:74,372,660...74,526,764 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19036983) Ensembl
MGI		 PMID:19036983 GO_REF:0000107 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865 		JBrowse link
G IFT172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16061793) Ensembl
MGI		 PMID:16061793 GO_REF:0000107 NCBI chr2A:27,448,139...27,492,302
Ensembl chr2A:27,536,534...27,580,406 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23395675) Ensembl
MGI		 PMID:23395675 GO_REF:0000107 Ensembl chr2A:103,042,328...103,078,190 JBrowse link
G KLK13 kallikrein related peptidase 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16423834) Ensembl
MGI		 PMID:16423834 GO_REF:0000107 NCBI chr19:48,022,614...48,032,624
Ensembl chr19:56,912,192...56,920,749 		JBrowse link
G LOC100982214 plasminogen acts_upstream_of_or_within ISO (PMID:34380733) MGI PMID:34380733 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G LOC100989368 Kell metallo-endopeptidase (Kell blood group) involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:134,897,567...135,237,214
Ensembl chr 7:147,423,103...147,443,895
Ensembl chr 7:147,423,103...147,443,895 		JBrowse link
G LOC100993088 endothelin-converting enzyme-like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:119,711,355...119,719,378
Ensembl chr2B:238,630,731...238,637,233 		JBrowse link
G LOC117978823 battenin acts_upstream_of_or_within ISO (PMID:15588329) MGI PMID:15588329
G LONP2 lon peptidase 2, peroxisomal involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr16:28,513,060...28,628,181
Ensembl chr16:47,405,018...47,511,124 		JBrowse link
G MAFB MAF bZIP transcription factor B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:37,023,988...37,027,446
Ensembl chr20:38,127,722...38,128,693 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,719,971...64,783,119
Ensembl chr16:84,063,508...84,126,000 		JBrowse link
G METAP2 methionyl aminopeptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:93,068,921...93,109,098
Ensembl chr12:96,461,549...96,503,508 		JBrowse link
G MME membrane metalloendopeptidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:152,085,694...152,240,148
Ensembl chr 3:160,197,566...160,292,119 		JBrowse link
G MMEL1 membrane metalloendopeptidase like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:1,323,914...1,362,178
Ensembl chr 1:2,462,621...2,504,213 		JBrowse link
G MMP16 matrix metallopeptidase 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:84,736,752...85,026,711
Ensembl chr 8:86,701,882...86,982,518 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (PMID:12970677) MGI PMID:12970677 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18325808) Ensembl
MGI		 PMID:18325808 GO_REF:0000107 NCBI chr17:14,772,054...14,780,398
Ensembl chr17:14,996,420...15,004,242 		JBrowse link
G NCSTN nicastrin involved_in ISO
IEA		 RGD
TreeGrafter
InterPro
Ensembl		 PMID:12736250 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:724403 NCBI chr 1:135,697,592...135,713,293
Ensembl chr 1:139,618,229...139,633,911 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921 		JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:11016935) MGI PMID:11016935 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068 		JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:180,862,434...180,921,197
Ensembl chr 3:189,032,816...189,088,036 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 involved_in ISO (PMID:9242664) RGD
BHF-UCL		 PMID:9242664 PMID:16497799 RGD:1601276 NCBI chr 5:18,917,488...18,960,102
Ensembl chr 5:19,064,004...19,106,486 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:16497799 GO_REF:0000107 RGD:1601276 NCBI chr20:17,184,878...17,443,355
Ensembl chr20:17,163,675...17,421,157 		JBrowse link
G PCSK4 proprotein convertase subtilisin/kexin type 4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr19:1,452,924...1,466,438 JBrowse link
G PCSK5 proprotein convertase subtilisin/kexin type 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15606899)
(PMID:21147780)		 MGI
Ensembl		 PMID:15606899 PMID:21147780 GO_REF:0000107 NCBI chr 9:48,480,607...48,943,331
Ensembl chr 9:74,745,761...75,220,502 		JBrowse link
G PCSK6 proprotein convertase subtilisin/kexin type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23918928) Ensembl
MGI		 PMID:23918928 GO_REF:0000107 NCBI chr15:80,029,225...80,226,027
Ensembl chr15:99,312,512...99,460,444 		JBrowse link
G PCSK7 proprotein convertase subtilisin/kexin type 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15606899) Ensembl
TreeGrafter
MGI		 PMID:15606899 GO_REF:0000107 GO_REF:0000118 NCBI chr11:112,035,502...112,066,170
Ensembl chr11:115,972,414...115,999,748 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 ISO RGD PMID:14622975 RGD:1582518 NCBI chr 1:54,323,036...54,355,397
Ensembl chr 1:55,911,016...55,936,456 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:14,663,847...14,859,294
Ensembl chr  X:22,017,681...22,232,501 		JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 ISO RGD PMID:11171063 RGD:628447 NCBI chr18:35,203,896...35,336,512
Ensembl chr18:38,754,789...38,882,037 		JBrowse link
G PITRM1 pitrilysin metallopeptidase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:3,135,895...3,171,235
Ensembl chr10:3,148,758...3,184,120 		JBrowse link
G PMPCA peptidase, mitochondrial processing subunit alpha ISO RGD PMID:2236012 RGD:1299588 NCBI chr 9:107,483,608...107,499,176
Ensembl chr 9:136,464,070...136,477,569 		JBrowse link
G PMPCB peptidase, mitochondrial processing subunit beta involved_in ISO PMID:10942759 UniProt PMID:10942759 RGD:38501073 NCBI chr 7:95,288,747...95,320,294
Ensembl chr 7:108,033,235...108,050,302 		JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma acts_upstream_of_or_within ISO (PMID:12297508) MGI PMID:12297508 NCBI chr14:82,383,086...82,549,822
Ensembl chr14:102,206,396...102,372,978 		JBrowse link
G PSEN1 presenilin 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:10206645)
(PMID:11567612)		 RGD
TreeGrafter
MGI
Ensembl
InterPro		 PMID:10206645 PMID:11567612 PMID:15456764 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1358417 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15280425) InterPro
TreeGrafter
MGI
Ensembl		 PMID:15280425 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:32,675,331...32,677,285
Ensembl chr19:41,409,662...41,411,089 		JBrowse link
G PTCH1 patched 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16061793) Ensembl
MGI		 PMID:16061793 GO_REF:0000107 NCBI chr 9:66,542,675...66,616,820
Ensembl chr 9:94,668,365...94,741,453 		JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (PMID:17328886) MGI PMID:17328886 NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750 		JBrowse link
G RCE1 Ras converting CAAX endopeptidase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr11:62,101,228...62,203,793
Ensembl chr11:65,427,937...65,522,087
Ensembl chr11:65,427,937...65,522,087 		JBrowse link
G RNPEP arginyl aminopeptidase ISO RGD PMID:16537183 RGD:1581649 NCBI chr 1:177,579,349...177,602,865
Ensembl chr 1:181,880,404...181,903,906 		JBrowse link
G SDE2 SDE2 telomere maintenance homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:201,443,945...201,460,668
Ensembl chr 1:206,441,517...206,457,679 		JBrowse link
G SPON1 spondin 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16227578) Ensembl
MGI		 PMID:16227578 GO_REF:0000107 NCBI chr11:14,063,166...14,368,180
Ensembl chr11:13,776,671...14,057,741 		JBrowse link
G SRGN serglycin involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:65,554,873...65,572,108
Ensembl chr10:68,089,392...68,106,250 		JBrowse link
G TLL1 tolloid like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:158,068,424...158,300,856
Ensembl chr 4:170,157,417...170,384,260 		JBrowse link
G TMPRSS12 transmembrane serine protease 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:32529245) Ensembl
MGI		 PMID:32529245 GO_REF:0000107 NCBI chr12:37,865,660...37,908,657
Ensembl chr12:38,768,072...38,810,372 		JBrowse link
G TMPRSS4 transmembrane serine protease 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:112,910,223...112,953,677
Ensembl chr11:116,843,287...116,884,767 		JBrowse link
G TYSND1 trypsin like peroxisomal matrix peptidase 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr10:66,609,736...66,619,838
Ensembl chr10:69,141,724...69,148,346 		JBrowse link
G XPNPEP3 X-prolyl aminopeptidase 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20179356) MGI
Ensembl		 PMID:20179356 GO_REF:0000107 NCBI chr22:21,752,015...21,827,146
Ensembl chr22:39,848,077...39,915,398 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11923874) Ensembl
MGI		 PMID:11923874 GO_REF:0000107 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747 		JBrowse link
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPH aspartate beta-hydroxylase involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr 8:57,921,580...58,134,778
Ensembl chr 8:59,629,707...59,843,658 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211 		JBrowse link
G CASP8 caspase 8 involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468 		JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr 5:152,667,136...152,796,575
Ensembl chr 5:159,292,029...159,418,077 		JBrowse link
G FADD Fas associated via death domain involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr11:65,300,889...65,305,020 JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in ISO (PMID:21575908) UniProt PMID:21575908 NCBI chr 1:134,364,706...134,405,910
Ensembl chr 1:138,152,328...138,203,424 		JBrowse link
G LGMN legumain involved_in ISO (PMID:9821970) ARUK-UCL PMID:9821970 NCBI chr14:73,337,607...73,383,462
Ensembl chr14:92,677,608...92,723,051 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in ISO (PMID:15882992) ARUK-UCL
CACAO		 PMID:15882992 NCBI chr2A:32,241,782...32,284,041
Ensembl chr2A:32,954,185...32,996,465 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:30248149) MGI PMID:30248149 NCBI chr11:274,904...281,590
Ensembl chr11:319,082...325,888 		JBrowse link
G PERP p53 apoptosis effector related to PMP22 involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr 6:135,845,845...135,863,603
Ensembl chr 6:139,931,031...139,947,792 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in ISO (PMID:23302887) CACAO PMID:23302887 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in ISO (PMID:11821383) UniProt PMID:11821383 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268 		JBrowse link
G TBC1D10A TBC1 domain family member 10A involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr22:11,328,159...11,363,009
Ensembl chr22:29,130,096...29,164,865 		JBrowse link
activation of plasma proteins involved in acute inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
angiotensin maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G ACE2 angiotensin converting enzyme 2 involved_in ISO (PMID:20357030)
(PMID:23462816)
(PMID:18263657)		 MGI PMID:18263657 PMID:20357030 PMID:23462816 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane involved_in ISO (PMID:8876246) MGI PMID:8876246 NCBI chr15:68,479,349...68,509,238
Ensembl chr15:87,681,826...87,703,713 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,026,525...33,052,252
Ensembl chr  X:40,730,677...40,756,209 		JBrowse link
G CPA3 carboxypeptidase A3 involved_in ISO (PMID:15173164) MGI PMID:15173164 NCBI chr 3:145,889,140...145,921,462
Ensembl chr 3:153,468,071...153,500,333 		JBrowse link
G ENPEP glutamyl aminopeptidase involved_in ISO (PMID:19228697)
(PMID:16889841)		 MGI PMID:16889841 PMID:19228697 NCBI chr 4:102,969,397...103,056,978
Ensembl chr 4:113,532,126...113,620,654 		JBrowse link
G MME membrane metalloendopeptidase involved_in ISO (PMID:28559246)
(PMID:27649628)		 MGI PMID:27649628 PMID:28559246 NCBI chr 3:152,085,694...152,240,148
Ensembl chr 3:160,197,566...160,292,119 		JBrowse link
G PRCP prolylcarboxypeptidase involved_in ISO (PMID:27649628) MGI PMID:27649628 NCBI chr11:77,890,115...77,967,056
Ensembl chr11:81,502,658...81,578,361 		JBrowse link
G PREP prolyl endopeptidase involved_in ISO (PMID:27649628) MGI PMID:27649628 NCBI chr 6:103,091,315...103,219,335
Ensembl chr 6:106,965,275...107,091,278 		JBrowse link
G REN renin involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:10617578) RGD
TreeGrafter
MGI
Ensembl		 PMID:10617578 PMID:21321306 GO_REF:0000107 GO_REF:0000118 RGD:5132599 NCBI chr 1:179,757,653...179,769,530
Ensembl chr 1:184,046,117...184,057,393 		JBrowse link
CAAX-box protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RCE1 Ras converting CAAX endopeptidase 1 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr11:62,101,228...62,203,793
Ensembl chr11:65,427,937...65,522,087
Ensembl chr11:65,427,937...65,522,087 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747 		JBrowse link
cytokine precursor processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP1 caspase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CMA1 chymase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:5,277,269...5,280,335
Ensembl chr14:23,400,345...23,403,548 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023 		JBrowse link
G PCSK5 proprotein convertase subtilisin/kexin type 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,480,607...48,943,331
Ensembl chr 9:74,745,761...75,220,502 		JBrowse link
dibasic protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023 		JBrowse link
endothelin maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ECE1 endothelin converting enzyme 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:20,166,019...20,290,803
Ensembl chr 1:21,206,199...21,278,909 		JBrowse link
enkephalin processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPE carboxypeptidase E ISO RGD PMID:6326144 RGD:6483103 NCBI chr 4:157,575,157...157,705,173
Ensembl chr 4:169,659,007...169,780,739 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:17,184,878...17,443,355
Ensembl chr20:17,163,675...17,421,157 		JBrowse link
epidermal growth factor receptor ligand maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:37,562,930...37,717,175
Ensembl chr15:55,873,606...56,027,188 		JBrowse link
G MEP1A meprin A subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:46,382,105...46,425,300
Ensembl chr 6:47,647,721...47,691,070 		JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD16 caspase recruitment domain family member 16 involved_in ISO (PMID:11432859) UniProt PMID:11432859 NCBI chr11:99,981,854...99,985,839
Ensembl chr11:103,467,368...103,468,288 		JBrowse link
G CARD8 caspase recruitment domain family member 8 involved_in ISO (PMID:11821383) UniProt PMID:11821383 NCBI chr19:45,204,735...45,256,481
Ensembl chr19:53,798,967...53,850,328 		JBrowse link
G CAST calpastatin involved_in ISO (PMID:2407243) CAFA PMID:2407243 NCBI chr 5:91,972,572...92,084,657
Ensembl chr 5:97,527,071...97,636,650 		JBrowse link
G CST7 cystatin F acts_upstream_of_or_within ISO (PMID:28251676) MGI PMID:28251676 NCBI chr20:24,889,834...24,900,766
Ensembl chr20:25,237,251...25,248,364 		JBrowse link
G NOL3 nucleolar protein 3 involved_in ISO PMID:16639714 UniProt PMID:16639714 RGD:10047164 NCBI chr16:47,516,156...47,521,441
Ensembl chr16:66,904,738...66,909,956 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in ISO (PMID:11865055) UniProt PMID:11865055 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606 		JBrowse link
insulin processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPE carboxypeptidase E involved_in
acts_upstream_of_or_within		 ISO (PMID:9348219)
(PMID:7663508)		 MGI
RGD		 PMID:2822027 PMID:7663508 PMID:9348219 PMID:12829804 RGD:1626225 RGD:405650689 NCBI chr 4:157,575,157...157,705,173
Ensembl chr 4:169,659,007...169,780,739 		JBrowse link
G ERO1B endoplasmic reticulum oxidoreductase 1 beta acts_upstream_of_or_within
involved_in		 ISO (PMID:20308425) MGI PMID:20308425 NCBI chr 1:211,782,071...211,849,308
Ensembl chr 1:216,786,605...216,850,463 		JBrowse link
G INS insulin involved_in ISO (PMID:20424817) MGI PMID:20424817 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:76,248,252...76,266,152
Ensembl chr17:81,950,422...81,968,109 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 involved_in ISO (PMID:12136131) MGI PMID:12136131 NCBI chr 5:18,917,488...18,960,102
Ensembl chr 5:19,064,004...19,106,486 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:17,184,878...17,443,355
Ensembl chr20:17,163,675...17,421,157 		JBrowse link
G SLC30A8 solute carrier family 30 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,624,785...113,851,633
Ensembl chr 8:116,223,595...116,394,095 		JBrowse link
G YIPF5 Yip1 domain family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:139,557,911...139,570,364
Ensembl chr 5:145,612,807...145,625,280 		JBrowse link
intein-mediated protein splicing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IHH Indian hedgehog signaling molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
islet amyloid polypeptide processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCSK2 proprotein convertase subtilisin/kexin type 2 involved_in ISO PMID:15983213 BHF-UCL PMID:15983213 RGD:8554260 NCBI chr20:17,184,878...17,443,355
Ensembl chr20:17,163,675...17,421,157 		JBrowse link
mitochondrial protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFG3L2 AFG3 like matrix AAA peptidase subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20038678)
(PMID:19656850)		 Ensembl
TreeGrafter
MGI		 PMID:19656850 PMID:20038678 GO_REF:0000107 GO_REF:0000118 NCBI chr18:1,951,279...1,999,313
Ensembl chr18:17,062,250...17,109,400 		JBrowse link
G ATP23 ATP23 metallopeptidase and ATP synthase assembly factor homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:30,969,266...30,985,043
Ensembl chr12:31,231,287...31,247,020 		JBrowse link
G OMA1 OMA1 zinc metallopeptidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20038678) Ensembl
TreeGrafter
MGI		 PMID:20038678 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:57,549,404...57,811,246
Ensembl chr 1:59,448,436...59,516,170 		JBrowse link
G SPG7 SPG7 matrix AAA peptidase subunit, paraplegin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:70,258,902...70,309,438
Ensembl chr16:89,866,884...89,917,867 		JBrowse link
G STOML2 stomatin like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,950,387...34,953,707
Ensembl chr 9:35,755,790...35,759,091 		JBrowse link
G YME1L1 YME1 like 1 ATPase involved_in ISO (PMID:27495975) UniProt PMID:27495975 NCBI chr10:27,220,951...27,263,841
Ensembl chr10:27,584,099...27,626,453 		JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPB2 carboxypeptidase B2 ISO RGD PMID:23369837 RGD:7243115 NCBI chr13:26,926,788...26,979,767 JBrowse link
G CTSZ cathepsin Z involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,346,241...55,358,354
Ensembl chr20:56,706,511...56,718,941 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,725,469...1,738,887
Ensembl chr17:1,618,549...1,631,570 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170 		JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:47,754,780...47,760,294
Ensembl chr19:56,649,018...56,653,909 		JBrowse link
G CDH1 cadherin 1 acts_upstream_of_or_within ISO (PMID:17344476) MGI PMID:17344476 NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,895,554...19,898,672
Ensembl chr15:38,145,730...38,148,698 		JBrowse link
G FMR1 fragile X messenger ribonucleoprotein 1 ISO Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:136,937,889...136,976,828
Ensembl chr  X:147,365,748...147,405,321 		JBrowse link
G GAS1 growth arrest specific 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:58,079,700...58,082,849
Ensembl chr 9:86,139,009...86,140,045 		JBrowse link
G GLG1 golgi glycoprotein 1 acts_upstream_of_or_within ISO (PMID:20530870) MGI PMID:20530870 NCBI chr16:55,014,892...55,172,877
Ensembl chr16:74,372,660...74,526,764 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23395675) Ensembl
MGI		 PMID:23395675 GO_REF:0000107 Ensembl chr2A:103,042,328...103,078,190 JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G NLRP7 NLR family pyrin domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:51,966,886...51,990,971
Ensembl chr19:60,662,184...60,677,844 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003 		JBrowse link
G SNX12 sorting nexin 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,327,484...60,336,682
Ensembl chr  X:70,384,164...70,395,737 		JBrowse link
G TMEM98 transmembrane protein 98 involved_in ISO (PMID:30249802) UniProt PMID:30249802 NCBI chr17:23,844,747...23,858,390
Ensembl chr17:24,133,357...24,146,912 		JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr12:117,867,453...117,887,968
Ensembl chr12:121,241,112...121,261,777 		JBrowse link
neuropeptide processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MME membrane metalloendopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:152,085,694...152,240,148
Ensembl chr 3:160,197,566...160,292,119 		JBrowse link
patched ligand maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DISP1 dispatched RND transporter family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12421714) Ensembl
MGI		 PMID:12421714 GO_REF:0000107 NCBI chr 1:198,488,047...198,679,013
Ensembl chr 1:203,628,338...203,692,218 		JBrowse link
peptide hormone processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORIN corin, serine peptidase involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 4:74,311,036...74,555,742
Ensembl chr 4:85,043,182...85,286,573 		JBrowse link
G ECE1 endothelin converting enzyme 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:20,166,019...20,290,803
Ensembl chr 1:21,206,199...21,278,909 		JBrowse link
G ECE2 endothelin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:181,310,554...181,327,602
Ensembl chr 3:189,766,786...189,811,206 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 involved_in ISO
IEA		 pituitary adenylate cyclase-activating polypetide RGD
TreeGrafter		 PMID:10087454 PMID:16497799 GO_REF:0000118 RGD:1601276 RGD:2308913 NCBI chr 5:18,917,488...18,960,102
Ensembl chr 5:19,064,004...19,106,486 		JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10632593) Ensembl
MGI		 PMID:10632593 GO_REF:0000107 NCBI chr  X:41,128,785...41,133,284
Ensembl chr  X:48,988,948...48,990,028 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12859669) RGD
TreeGrafter
MGI
Ensembl		 PMID:12859669 PMID:16497799 GO_REF:0000107 GO_REF:0000118 RGD:1601276 NCBI chr20:17,184,878...17,443,355
Ensembl chr20:17,163,675...17,421,157 		JBrowse link
G PCSK4 proprotein convertase subtilisin/kexin type 4 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr19:1,452,924...1,466,438 JBrowse link
G PCSK5 proprotein convertase subtilisin/kexin type 5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:48,480,607...48,943,331
Ensembl chr 9:74,745,761...75,220,502 		JBrowse link
G PCSK6 proprotein convertase subtilisin/kexin type 6 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:8070361 GO_REF:0000107 GO_REF:0000118 RGD:729476 NCBI chr15:80,029,225...80,226,027
Ensembl chr15:99,312,512...99,460,444 		JBrowse link
G SCG5 secretogranin V involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:11,136,920...11,192,606
Ensembl chr15:29,974,633...30,030,291 		JBrowse link
plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16407971) Ensembl
MGI		 PMID:16407971 GO_REF:0000107 NCBI chr 1:54,126,170...54,163,713
Ensembl chr 1:55,714,693...55,754,698 		JBrowse link
G F11 coagulation factor XI involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G FGA fibrinogen alpha chain involved_in ISO (PMID:16846481) UniProt PMID:16846481 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G KLKB1 kallikrein B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100979289 histone H2B type 1-A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17690254) Ensembl
MGI		 PMID:17690254 GO_REF:0000107 NCBI chr 6:25,561,518...25,562,817
Ensembl chr 6:25,887,397...25,887,780 		JBrowse link
G PGK1 phosphoglycerate kinase 1 involved_in ISO (PMID:11130727) CAFA PMID:11130727 NCBI chr  X:67,280,269...67,302,307
Ensembl chr  X:77,391,805...77,414,459 		JBrowse link
G PLAT plasminogen activator, tissue type involved_in ISO
IEA		 RGD
TreeGrafter
InterPro
Ensembl		 PMID:8343497 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:11537479 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G PLAU plasminogen activator, urokinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136 		JBrowse link
G TMPRSS9 transmembrane serine protease 9 acts_upstream_of_or_within ISO (PMID:16872279) MGI PMID:16872279 NCBI chr19:1,402,052...1,438,710
Ensembl chr19:2,373,815...2,404,215 		JBrowse link
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250 		JBrowse link
G CLEC3B C-type lectin domain family 3 member B involved_in ISO (PMID:12694198) UniProt PMID:12694198 NCBI chr 3:44,927,098...44,936,847
Ensembl chr 3:46,038,115...46,047,927 		JBrowse link
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215 		JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G HPN hepsin involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,985,761...32,012,841
Ensembl chr19:40,725,319...40,750,628 		JBrowse link
G MELTF melanotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:194,345,474...194,373,690
Ensembl chr 3:204,262,182...204,310,710 		JBrowse link
G PLGRKT plasminogen receptor with a C-terminal lysine involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19897580) InterPro
TreeGrafter
MGI
Ensembl		 PMID:19897580 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:5,196,843...5,257,138
Ensembl chr 9:5,382,302...5,441,993 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 ISO RGD PMID:11027681 RGD:67924 NCBI chr 3:125,120,524...125,200,859
Ensembl chr 3:132,486,229...132,528,918 		JBrowse link
G S100A10 S100 calcium binding protein A10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:127,341,974...127,353,054
Ensembl chr 1:130,985,312...130,995,130 		JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPTL8 angiopoietin like 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23150577) MGI
Ensembl		 PMID:23150577 GO_REF:0000107 NCBI chr19:10,787,457...10,790,090
Ensembl chr19:11,498,069...11,500,400 		JBrowse link
G ASTL astacin like metalloendopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:103,176,662...103,192,542
Ensembl chr2A:97,049,184...97,063,747 		JBrowse link
G BAG2 BAG cochaperone 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,730,297...56,743,123
Ensembl chr 6:58,360,889...58,373,733 		JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,819,591...53,087,772
Ensembl chr18:56,149,036...56,412,222 		JBrowse link
G CNTN2 contactin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18278038) MGI
Ensembl		 PMID:18278038 GO_REF:0000107 NCBI chr 1:180,645,259...180,680,081
Ensembl chr 1:184,931,497...184,966,482 		JBrowse link
G CTNND1 catenin delta 1 acts_upstream_of_or_within ISO (PMID:17344476) MGI PMID:17344476 NCBI chr11:53,000,582...53,058,054
Ensembl chr11:56,470,174...56,527,593 		JBrowse link
G FUZ fuzzy planar cell polarity protein acts_upstream_of_or_within ISO (PMID:19877275) MGI PMID:19877275 NCBI chr19:46,819,833...46,826,235
Ensembl chr19:55,736,325...55,742,589 		JBrowse link
G MBL2 mannose binding lectin 2 ISO Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO RGD PMID:14668206 RGD:1582606 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:1,075,172...1,081,664 JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:32,241,782...32,284,041
Ensembl chr2A:32,954,185...32,996,465 		JBrowse link
G RHBDD1 rhomboid domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:114,041,381...114,245,220
Ensembl chr2B:232,897,487...233,057,578 		JBrowse link
G SPON1 spondin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227578) Ensembl
MGI		 PMID:16227578 GO_REF:0000107 NCBI chr11:14,063,166...14,368,180
Ensembl chr11:13,776,671...14,057,741 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17344476) Ensembl
MGI		 PMID:17344476 GO_REF:0000107 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G TIMM17A translocase of inner mitochondrial membrane 17A ISO RGD PMID:9756630 RGD:13463485 NCBI chr 1:177,552,399...177,567,148
Ensembl chr 1:181,854,412...181,868,960 		JBrowse link
G TIMM23 translocase of inner mitochondrial membrane 23 ISO RGD PMID:9756630 RGD:13463485 NCBI chr10:43,123,802...43,157,666 JBrowse link
G TNP1 transition protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:104,122,748...104,123,349
Ensembl chr2B:222,723,606...222,724,212 		JBrowse link
G TNP2 transition protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr16:10,209,801...10,211,466
Ensembl chr16:11,431,822...11,433,087 		JBrowse link
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831 		JBrowse link
G MYH9 myosin heavy chain 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618 		JBrowse link
protein autoprocessing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFG3L2 AFG3 like matrix AAA peptidase subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:1,951,279...1,999,313
Ensembl chr18:17,062,250...17,109,400 		JBrowse link
G CAPN1 calpain 1 ISO RGD PMID:17182728 RGD:2303057 NCBI chr11:60,545,837...60,576,631
Ensembl chr11:63,886,015...63,916,021 		JBrowse link
G CAPN2 calpain 2 ISO RGD PMID:17182728 RGD:2303057 NCBI chr 1:199,335,582...199,399,267
Ensembl chr 1:204,335,573...204,409,150 		JBrowse link
G CASP1 caspase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CASP4 caspase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,883,353...99,909,185
Ensembl chr11:103,366,138...103,391,824 		JBrowse link
G CASP6 caspase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:102,186,215...102,201,992
Ensembl chr 4:112,753,988...112,768,836 		JBrowse link
G CTSE cathepsin E ISO RGD PMID:16367762 RGD:2325171 NCBI chr 1:181,617,421...181,632,260
Ensembl chr 1:185,900,746...185,915,519 		JBrowse link
G CTSL cathepsin L involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:58,851,899...58,857,170
Ensembl chr 9:86,903,006...86,908,303 		JBrowse link
G DHH desert hedgehog signaling molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr12:39,656,046...39,661,439
Ensembl chr12:40,535,740...40,541,123 		JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G FAM111A FAM111 trypsin like peptidase A involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:54,359,711...54,372,132
Ensembl chr11:57,818,413...57,823,046 		JBrowse link
G FXN frataxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,690,483...55,754,755
Ensembl chr 9:67,800,579...67,866,031 		JBrowse link
G HJV hemojuvelin BMP co-receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:121,738,465...121,742,743
Ensembl chr 1:113,926,383...113,930,761 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506 		JBrowse link
G MYRF myelin regulatory factor involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr11:57,052,219...57,088,105
Ensembl chr11:60,412,780...60,448,579 		JBrowse link
G MYRFL myelin regulatory factor like involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr12:70,115,696...70,247,593 JBrowse link
G OMA1 OMA1 zinc metallopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:57,549,404...57,811,246
Ensembl chr 1:59,448,436...59,516,170 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:16093393 RGD:1601081 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO RGD PMID:9556596 RGD:2308914 NCBI chr 5:18,917,488...18,960,102
Ensembl chr 5:19,064,004...19,106,486 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:17,184,878...17,443,355
Ensembl chr20:17,163,675...17,421,157 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in ISO
IEA		 RGD
Ensembl		 PMID:14622975 GO_REF:0000107 RGD:1582518 NCBI chr 1:54,323,036...54,355,397
Ensembl chr 1:55,911,016...55,936,456 		JBrowse link
G PIDD1 p53-induced death domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436 		JBrowse link
G PISD phosphatidylserine decarboxylase involved_in IEA UniProt GO_REF:0000104 NCBI chr22:12,638,418...12,682,733
Ensembl chr22:30,495,546...30,539,389 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SPRTN SprT-like N-terminal domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:206,889,897...206,906,047
Ensembl chr 1:211,914,082...211,931,093 		JBrowse link
G TMPRSS2 transmembrane serine protease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:27,800,466...27,843,395
Ensembl chr21:41,131,515...41,161,088 		JBrowse link
protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IMMP1L inner mitochondrial membrane peptidase subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:31,396,011...31,473,342
Ensembl chr11:31,285,619...31,362,843 		JBrowse link
G IMMP2L inner mitochondrial membrane peptidase subunit 2 acts_upstream_of_or_within ISO (PMID:15814844) MGI PMID:15814844 NCBI chr 7:102,647,212...103,536,293 JBrowse link
G MIPEP mitochondrial intermediate peptidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:5,040,237...5,207,674
Ensembl chr13:23,334,267...23,500,582 		JBrowse link
G PMPCA peptidase, mitochondrial processing subunit alpha involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:107,483,608...107,499,176
Ensembl chr 9:136,464,070...136,477,569 		JBrowse link
G PMPCB peptidase, mitochondrial processing subunit beta involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12433926 GO_REF:0000107 GO_REF:0000118 RGD:13463464 NCBI chr 7:95,288,747...95,320,294
Ensembl chr 7:108,033,235...108,050,302 		JBrowse link
regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) UniProt PMID:10924275
G CWH43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:34380733) MGI
Ensembl		 PMID:34380733 GO_REF:0000107 NCBI chr 4:73,092,093...73,168,001
Ensembl chr 4:83,820,733...83,896,296 		JBrowse link
G IFT52 intraflagellar transport 52 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15930098) Ensembl
MGI		 PMID:15930098 GO_REF:0000107 NCBI chr20:39,929,523...39,986,072
Ensembl chr20:41,023,517...41,080,500 		JBrowse link
G IFT88 intraflagellar transport 88 acts_upstream_of_or_within ISO (PMID:16254602)
(PMID:15930098)		 MGI PMID:15930098 PMID:16254602 NCBI chr13:1,893,102...2,017,771
Ensembl chr13:20,206,471...20,331,204 		JBrowse link
G INPP5B inositol polyphosphate-5-phosphatase B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11784089) Ensembl
MGI		 PMID:11784089 GO_REF:0000107 NCBI chr 1:37,135,442...37,220,721
Ensembl chr 1:38,485,163...38,567,704 		JBrowse link
G LDLRAD3 low density lipoprotein receptor class A domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21795536) Ensembl
MGI		 PMID:21795536 GO_REF:0000107 NCBI chr11:35,917,271...36,204,509
Ensembl chr11:35,791,899...36,076,358 		JBrowse link
G NOTCH4 notch receptor 4 acts_upstream_of_or_within ISO (PMID:24667410) MGI PMID:24667410 NCBI chr 6:31,842,233...31,871,412
Ensembl chr 6:32,722,112...32,750,978 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22007132) Ensembl
MGI		 PMID:22007132 GO_REF:0000107 NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22007132) Ensembl
MGI		 PMID:22007132 GO_REF:0000107 NCBI chr 1:116,625,640...116,786,396
Ensembl chr 1:85,487,681...85,644,253 		JBrowse link
G PRSS37 serine protease 37 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:133,767,802...133,773,321
Ensembl chr 7:146,236,906...146,242,157 		JBrowse link
G RFX4 regulatory factor X4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19887680) Ensembl
MGI		 PMID:19887680 GO_REF:0000107 NCBI chr12:104,152,816...104,330,383
Ensembl chr12:107,550,254...107,724,623 		JBrowse link
G RNF139 ring finger protein 139 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:121,158,715...121,172,069
Ensembl chr 8:123,912,589...123,924,720 		JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:16585392) MGI PMID:16585392 NCBI chr 6:164,373,829...164,829,195
Ensembl chr 6:169,355,136...169,806,337 		JBrowse link
signal peptide processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN5 CLN5 intracellular trafficking protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023 		JBrowse link
G HM13 histocompatibility minor 13 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:27,803,597...27,859,384
Ensembl chr20:28,441,285...28,501,001 		JBrowse link
G IMMP1L inner mitochondrial membrane peptidase subunit 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:31,396,011...31,473,342
Ensembl chr11:31,285,619...31,362,843 		JBrowse link
G LOC100973796 putative signal peptidase complex catalytic subunit SEC11B involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr 8:50,948,305...50,948,888 JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:180,862,434...180,921,197
Ensembl chr 3:189,032,816...189,088,036 		JBrowse link
G PCSK5 proprotein convertase subtilisin/kexin type 5 involved_in ISO (PMID:16912035) HGNC-UCL PMID:16912035 NCBI chr 9:48,480,607...48,943,331
Ensembl chr 9:74,745,761...75,220,502 		JBrowse link
G SEC11A SEC11 homolog A, signal peptidase complex subunit involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr15:63,337,266...63,384,532 JBrowse link
G SEC11C SEC11 homolog C, signal peptidase complex subunit involved_in IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr18:52,534,718...52,553,726
Ensembl chr18:55,860,471...55,880,060 		JBrowse link
G SPCS1 signal peptidase complex subunit 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 3:52,646,427...52,648,786
Ensembl chr 3:53,873,921...53,876,229 		JBrowse link
G SPCS2 signal peptidase complex subunit 2 involved_in IEA InterPro
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr11:70,013,810...70,042,618
Ensembl chr11:73,319,200...73,347,960 		JBrowse link
G SPCS3 signal peptidase complex subunit 3 involved_in ISO (PMID:34388369) ComplexPortal PMID:34388369 NCBI chr 4:168,502,522...168,514,965 JBrowse link
G SPPL3 signal peptide peptidase like 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:118,351,199...118,489,579
Ensembl chr12:121,723,881...121,773,429 		JBrowse link
signaling receptor ligand precursor processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:37,562,930...37,717,175
Ensembl chr15:55,873,606...56,027,188 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:28751722)
(PMID:14993236), (PMID:17169360)		 MGI PMID:14993236 PMID:17169360 PMID:28751722 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054 		JBrowse link
G BACE1 beta-secretase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:112,120,950...112,151,505
Ensembl chr11:116,054,303...116,084,812 		JBrowse link
G BACE2 beta-secretase 2 involved_in ISO (PMID:31838721) MGI PMID:31838721 NCBI chr21:27,500,453...27,612,795
Ensembl chr21:40,831,203...40,938,280 		JBrowse link
G CASP1 caspase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CSTL1 cystatin like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:23,374,982...23,380,933
Ensembl chr20:23,725,896...23,731,152 		JBrowse link
G MEP1A meprin A subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:46,382,105...46,425,300
Ensembl chr 6:47,647,721...47,691,070 		JBrowse link
trypsinogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUZD1 CUB and zona pellucida like domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:119,395,492...119,409,696
Ensembl chr10:123,667,289...123,716,925 		JBrowse link
vacuolar protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LGMN legumain involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:73,337,607...73,383,462
Ensembl chr14:92,677,608...92,723,051 		JBrowse link
G TMEM208 transmembrane protein 208 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:47,572,655...47,574,836
Ensembl chr16:66,961,504...66,963,680 		JBrowse link
zymogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1R complement C1r involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:7,211,162...7,222,673
Ensembl chr12:7,126,723...7,137,895 		JBrowse link
G C1RL complement C1r subcomponent like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:7,224,675...7,239,524
Ensembl chr12:7,139,094...7,155,196 		JBrowse link
G CD5L CD5 molecule like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:133,192,387...133,203,293
Ensembl chr 1:136,985,701...136,996,263 		JBrowse link
G CD6 CD6 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:56,269,585...56,283,516
Ensembl chr11:59,675,221...59,722,916 		JBrowse link
G CTSH cathepsin H involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:57,893,379...57,917,194
Ensembl chr15:76,852,668...76,876,976 		JBrowse link
G CTSL cathepsin L involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:58,851,899...58,857,170
Ensembl chr 9:86,903,006...86,908,303 		JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F9 coagulation factor IX involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 involved_in ISO (PMID:23682772) UniProt PMID:23682772 NCBI chr22:5,424,334...5,469,705 JBrowse link
G HGFAC HGF activator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:3,590,908...3,599,781
Ensembl chr 4:3,575,819...3,583,436 		JBrowse link
G KLK1 kallikrein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:47,784,368...47,789,004
Ensembl chr19:56,677,579...56,682,216 		JBrowse link
G KLK2 kallikrein related peptidase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:47,837,464...47,847,626 JBrowse link
G KLK3 kallikrein related peptidase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:47,820,320...47,827,868
Ensembl chr19:56,712,305...56,718,123 		JBrowse link
G LOC100972567 haptoglobin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:52,907,739...52,912,781
Ensembl chr16:71,901,278...71,905,998 		JBrowse link
G LOC100983226 scavenger receptor cysteine-rich domain-containing protein SCART1-like involved_in IEA TreeGrafter GO_REF:0000118
G LOC103782687 haptoglobin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:52,942,214...52,947,034
Ensembl chr16:71,901,278...71,905,998 		JBrowse link
G LOC103783441 haptoglobin-related protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:52,926,044...52,940,038
Ensembl chr16:71,901,278...71,905,998 		JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15572153) Ensembl
TreeGrafter
MGI		 PMID:15572153 GO_REF:0000107 GO_REF:0000118 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058 		JBrowse link
G MSR1 macrophage scavenger receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:15,335,795...15,421,472
Ensembl chr 8:12,088,873...12,175,927 		JBrowse link
G OMA1 OMA1 zinc metallopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:57,549,404...57,811,246
Ensembl chr 1:59,448,436...59,516,170 		JBrowse link
G PRSS12 serine protease 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17223089) Ensembl
MGI		 PMID:17223089 GO_REF:0000107 NCBI chr 4:110,727,731...110,801,258
Ensembl chr 4:121,279,868...121,353,151 		JBrowse link
G PRSS3 serine protease 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:33,589,522...33,637,991
Ensembl chr 9:34,401,323...34,449,666 		JBrowse link
G SCARA5 scavenger receptor class A member 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:27,143,737...27,271,301
Ensembl chr 8:24,345,260...24,469,881 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:68,218,230...68,243,687
Ensembl chr10:70,742,062...70,767,613 		JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme involved_in ISO (PMID:11799113), (PMID:9130696) UniProt PMID:9130696 PMID:11799113 NCBI chr15:69,560,774...69,576,007
Ensembl chr15:88,763,269...88,774,023 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    cellular process 16207
      metabolic process 10770
        macromolecule metabolic process 8862
          protein metabolic process 4592
            protein maturation 571
              protein processing 262
                CAAX-box protein processing 2
                Notch receptor processing, ligand-independent 0
                activation of plasma proteins involved in acute inflammatory response + 2
                dibasic protein processing + 1
                mitochondrial protein processing + 12
                negative regulation of protein processing + 27
                positive regulation of protein processing + 29
                protein autoprocessing 26
                protein processing in phagocytic vesicle + 2
                protein splicing + 2
                regulation of protein processing + 69
                signal peptide processing + 13
                signaling receptor ligand precursor processing + 36
                vacuolar protein processing 2
                zymogen activation + 66
Path 2
Term Annotations click to browse term
  biological_process 16644
    cellular process 16207
      metabolic process 10770
        biosynthetic process 7634
          macromolecule biosynthetic process 6719
            gene expression 6307
              protein maturation 571
                protein processing 262
                  CAAX-box protein processing 2
                  Notch receptor processing, ligand-independent 0
                  activation of plasma proteins involved in acute inflammatory response + 2
                  dibasic protein processing + 1
                  mitochondrial protein processing + 12
                  negative regulation of protein processing + 27
                  positive regulation of protein processing + 29
                  protein autoprocessing 26
                  protein processing in phagocytic vesicle + 2
                  protein splicing + 2
                  regulation of protein processing + 69
                  signal peptide processing + 13
                  signaling receptor ligand precursor processing + 36
                  vacuolar protein processing 2
                  zymogen activation + 66
paths to the root