FKRP (fukutin related protein) - Rat Genome Database

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Pathways
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Gene: FKRP (fukutin related protein) Pan paniscus
Analyze
Symbol: FKRP
Name: fukutin related protein
RGD ID: 11947210
Description: ENCODES a protein that exhibits dystroglycan binding (inferred); identical protein binding (inferred); laminin binding (inferred); INVOLVED IN adult walking behavior (ortholog); basement membrane organization (ortholog); bone mineralization (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2I (ortholog); cardiomyopathy (ortholog); FOUND IN Golgi apparatus (ortholog); skeletal muscle myofibril (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ribitol 5-phosphate transferase FKRP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,895,811 - 52,905,652 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,766,677 - 54,776,808 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,738,339 - 43,748,250 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,268,889 - 52,277,888 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,273,546 - 52,276,341 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult walking behavior  (IEA,ISO)
basement membrane organization  (IEA,ISO)
bone mineralization  (IEA,ISO)
brain development  (IEA,ISO)
camera-type eye development  (IEA,ISO)
central nervous system development  (IEA,ISO)
connective tissue development  (IEA,ISO)
connective tissue replacement  (IEA,ISO)
creatine metabolic process  (IEA,ISO)
diaphragm development  (IEA,ISO)
extracellular matrix organization  (IEA,ISO)
eye development  (IEA,ISO)
filtration diaphragm assembly  (IEA,ISO)
gene expression  (IEA,ISO)
glial cell differentiation  (IEA,ISO)
glycolytic process  (IEA,ISO)
glycoprotein biosynthetic process  (IEA,ISO)
heart development  (IEA,ISO)
heart morphogenesis  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
inflammatory response  (IEA,ISO)
lipid metabolic process  (IEA,ISO)
localization of cell  (IEA,ISO)
maintenance of protein localization in endoplasmic reticulum  (IEA,ISO)
muscle cell differentiation  (IEA,ISO)
muscle contraction  (IEA,ISO)
muscle structure development  (IEA,ISO)
neuromuscular process  (IEA,ISO)
neuron migration  (IEA,ISO)
oxygen metabolic process  (IEA,ISO)
pentitol metabolic process  (IEA,ISO)
pentose metabolic process  (IEA,ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA,ISO)
protein glycosylation  (IEA,ISO)
protein import  (IEA,ISO)
protein localization  (IEA,ISO)
protein modification process  (IEA,ISO)
protein O-linked mannosylation  (IEA,ISO)
protein processing  (IEA,ISO)
protein tetramerization  (IEA)
reelin-mediated signaling pathway  (IEA,ISO)
respiratory system process  (IEA,ISO)
response to activity  (IEA,ISO)
response to alcohol  (IEA,ISO)
response to glucocorticoid  (IEA,ISO)
response to xenobiotic stimulus  (IEA,ISO)
skeletal muscle fiber differentiation  (IEA,ISO)
skeletal muscle organ development  (IEA,ISO)
skeletal muscle tissue development  (IEA,ISO)
skeletal muscle tissue regeneration  (IEA,ISO)
striated muscle cell differentiation  (IEA,ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FKRP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,895,811 - 52,905,652 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,766,677 - 54,776,808 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,738,339 - 43,748,250 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,268,889 - 52,277,888 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,273,546 - 52,276,341 (+)Ensemblpanpan1.1panPan2
FKRP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,744,760 - 46,758,575 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,746,046 - 46,776,988 (+)EnsemblGRCh38hg38GRCh38
GRCh371947,249,314 - 47,261,832 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,941,143 - 51,953,582 (+)NCBINCBI36Build 36hg18NCBI36
Build 341951,941,154 - 51,953,581NCBI
Celera1944,052,833 - 44,066,103 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,674,242 - 43,686,703 (+)NCBIHuRef
CHM1_11947,251,200 - 47,263,719 (+)NCBICHM1_1
T2T-CHM13v2.01949,570,337 - 49,584,398 (+)NCBIT2T-CHM13v2.0
Fkrp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,543,192 - 16,550,657 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,543,171 - 16,550,657 (-)EnsemblGRCm39 Ensembl
GRCm38716,809,267 - 16,816,732 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,809,246 - 16,816,732 (-)EnsemblGRCm38mm10GRCm38
MGSCv37717,394,616 - 17,402,081 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,967,789 - 15,975,237 (-)NCBIMGSCv36mm8
Celera714,007,271 - 14,014,735 (-)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
Fkrp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,607,769 - 86,615,045 (-)NCBIGRCr8
mRatBN7.2177,479,641 - 77,486,954 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,476,084 - 77,486,992 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,859,819 - 82,865,434 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,423,863 - 91,429,478 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,614,910 - 84,620,525 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,733,461 - 78,740,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,733,508 - 78,739,107 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,980,656 - 79,987,961 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,133,884 - 77,139,485 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,211,994 - 77,217,596 (-)NCBI
Celera171,964,734 - 71,970,335 (-)NCBICelera
Cytogenetic Map1q21NCBI
Fkrp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574786,758 - 788,348 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955574779,672 - 789,621 (+)NCBIChiLan1.0ChiLan1.0
FKRP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,166,527 - 109,177,393 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,168,644 - 109,178,319 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,646,333 - 108,657,154 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,692,868 - 109,703,829 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,693,019 - 109,702,692 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,370,001 - 109,380,952 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,004,334 - 109,015,149 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,872,874 - 109,883,835 (-)NCBIUU_Cfam_GSD_1.0
Fkrp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934918,958,974 - 18,968,719 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936664578,126 - 586,795 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936664577,109 - 586,848 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKRP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,627,471 - 52,639,253 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,627,466 - 52,639,255 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,948,142 - 47,957,965 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FKRP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,100,399 - 40,128,340 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,126,321 - 40,127,808 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,812,461 - 19,825,085 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fkrp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,849,005 - 6,857,898 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,849,001 - 6,858,931 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034946210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034946211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034946212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034946213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034946214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034946215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034946217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034946219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057300685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063600431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063600432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000051216   ⟹   ENSPPAP00000028369
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1952,273,546 - 52,276,341 (+)Ensembl
RefSeq Acc Id: XM_034946210   ⟹   XP_034802101
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,895,811 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,766,677 - 54,776,808 (+)NCBI
Mhudiblu_PPA_v01943,738,346 - 43,748,250 (+)NCBI
RefSeq Acc Id: XM_034946213   ⟹   XP_034802104
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,897,083 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,767,949 - 54,776,808 (+)NCBI
Mhudiblu_PPA_v01943,739,951 - 43,748,250 (+)NCBI
RefSeq Acc Id: XM_034946215   ⟹   XP_034802106
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,895,811 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,766,677 - 54,776,808 (+)NCBI
Mhudiblu_PPA_v01943,738,339 - 43,748,250 (+)NCBI
RefSeq Acc Id: XM_034946217   ⟹   XP_034802108
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,896,640 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,767,510 - 54,776,808 (+)NCBI
Mhudiblu_PPA_v01943,739,172 - 43,748,250 (+)NCBI
RefSeq Acc Id: XM_055103989   ⟹   XP_054959964
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,896,299 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,767,510 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_055103991   ⟹   XP_054959966
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,895,815 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,766,681 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_055103993   ⟹   XP_054959968
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,896,290 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,767,156 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_055103994   ⟹   XP_054959969
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,896,640 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,767,510 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_055103995   ⟹   XP_054959970
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,896,297 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,767,186 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_055103996   ⟹   XP_054959971
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,896,640 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,767,510 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_055103997   ⟹   XP_054959972
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,895,827 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,766,696 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_055103998   ⟹   XP_054959973
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,895,827 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,766,693 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_055103999   ⟹   XP_054959974
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,896,295 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,767,157 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_057300685   ⟹   XP_057156668
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,895,811 - 52,905,652 (+)NCBI
NHGRI_mPanPan11954,766,684 - 54,776,808 (+)NCBI
RefSeq Acc Id: XM_063600431   ⟹   XP_063456501
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,895,811 - 52,905,652 (+)NCBI
RefSeq Acc Id: XM_063600432   ⟹   XP_063456502
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22052,895,825 - 52,905,652 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034802106   ⟸   XM_034946215
- UniProtKB: A0A2R9BFE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034802101   ⟸   XM_034946210
- UniProtKB: A0A2R9BFE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034802108   ⟸   XM_034946217
- UniProtKB: A0A2R9BFE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034802104   ⟸   XM_034946213
- UniProtKB: A0A2R9BFE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000028369   ⟸   ENSPPAT00000051216
RefSeq Acc Id: XP_054959966   ⟸   XM_055103991
RefSeq Acc Id: XP_054959973   ⟸   XM_055103998
RefSeq Acc Id: XP_054959972   ⟸   XM_055103997
RefSeq Acc Id: XP_054959968   ⟸   XM_055103993
RefSeq Acc Id: XP_054959974   ⟸   XM_055103999
RefSeq Acc Id: XP_054959970   ⟸   XM_055103995
RefSeq Acc Id: XP_054959964   ⟸   XM_055103989
RefSeq Acc Id: XP_054959971   ⟸   XM_055103996
RefSeq Acc Id: XP_054959969   ⟸   XM_055103994
RefSeq Acc Id: XP_057156668   ⟸   XM_057300685
RefSeq Acc Id: XP_063456501   ⟸   XM_063600431
RefSeq Acc Id: XP_063456502   ⟸   XM_063600432


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037227 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051216.1 UniProtKB/TrEMBL
NCBI Gene FKRP ENTREZGENE
PANTHER FUKUTIN RELATED PROTEIN UniProtKB/TrEMBL
  FUKUTIN-RELATED PROTEIN UniProtKB/TrEMBL
UniProt A0A2R9BFE2 ENTREZGENE, UniProtKB/TrEMBL