ATG4A (autophagy related 4A cysteine peptidase)

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Gene: ATG4A (autophagy related 4A cysteine peptidase) Pan paniscus

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Symbol:

ATG4A

Name:

autophagy related 4A cysteine peptidase

RGD ID:

11968116

Description:

ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); protein-phosphatidylethanolamide deconjugating activity (inferred); INVOLVED IN protein delipidation (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); Charcot-Marie-Tooth disease type X (ortholog); FOUND IN cytoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cysteine protease ATG4A

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	107,572,779 - 107,636,591 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	107,576,410 - 107,640,195 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	97,189,556 - 97,253,371 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	107,559,639 - 107,623,389 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	107,559,639 - 107,623,389 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

Charcot-Marie-Tooth disease type X (ISO)

factor VIII deficiency (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

X-linked Alport syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aggrephagy (IEA)

autophagosome assembly (IEA)

autophagy (IEA)

lipid metabolic process (IEA)

mitophagy (IEA)

piecemeal microautophagy of the nucleus (IEA)

protein delipidation (ISO)

protein processing (IEA)

protein transport (IEA)

proteolysis (IEA)

Cellular Component

cytoplasm (IEA)

Molecular Function

cysteine-type endopeptidase activity (IEA)

cysteine-type peptidase activity (IEA)

protein binding (ISO)

protein-phosphatidylethanolamide deconjugating activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

autophagy pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

ATG4A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	107,572,779 - 107,636,591 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	107,576,410 - 107,640,195 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	97,189,556 - 97,253,371 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	107,559,639 - 107,623,389 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	107,559,639 - 107,623,389 (+)	Ensembl	panpan1.1		panPan2

ATG4A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	108,088,829 - 108,154,671 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	108,091,668 - 108,154,671 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	107,335,008 - 107,397,901 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	107,221,590 - 107,284,552 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	X	107,806,406 - 107,869,363 (+)	NCBI		Celera
Cytogenetic Map	X	q22.3	NCBI
HuRef	X	96,957,585 - 97,020,331 (+)	NCBI		HuRef
CHM1_1	X	107,245,775 - 107,308,734 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	106,526,530 - 106,592,262 (+)	NCBI		T2T-CHM13v2.0

Atg4a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	139,854,594 - 139,947,190 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	139,857,656 - 139,947,266 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	140,953,845 - 141,164,194 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	140,956,907 - 141,164,270 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	137,593,241 - 137,598,813 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv37	X	137,491,456 - 137,529,979 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	136,303,271 - 136,342,019 (+)	NCBI		MGSCv36	mm8
Celera	X	124,212,154 - 124,250,668 (+)	NCBI		Celera
Celera	X	125,167,353 - 125,172,805 (+)	NCBI		Celera
Cytogenetic Map	X	F1	NCBI
cM Map	X	61.67	NCBI

Atg4a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	109,453,712 - 109,553,758 (+)	NCBI		GRCr8
mRatBN7.2	X	104,665,345 - 104,765,271 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	104,665,345 - 104,765,268 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	106,794,654 - 106,894,585 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	110,294,013 - 110,393,796 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	107,848,029 - 107,952,306 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	112,328,907 - 112,403,157 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	52,231,912 - 52,273,743 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	X	104,178,429 - 104,184,592 (+)	NCBI		Celera
Cytogenetic Map	X	q33	NCBI

Atg4a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955490	7,762,623 - 7,788,705 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955490	7,765,145 - 7,825,126 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATG4A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	81,629,346 - 81,688,086 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	81,629,465 - 81,688,099 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	67,753,046 - 67,808,661 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	83,281,769 - 83,337,418 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	83,279,008 - 83,337,403 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	80,740,818 - 80,796,428 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	82,453,368 - 82,509,012 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	82,244,510 - 82,299,838 (+)	NCBI		UU_Cfam_GSD_1.0

Atg4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	80,966,279 - 81,016,771 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	6,640,957 - 6,691,995 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	6,641,192 - 6,691,685 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATG4A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	88,548,751 - 88,633,321 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	88,545,924 - 88,633,328 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	103,050,536 - 103,071,241 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATG4A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	95,936,385 - 96,011,541 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	95,983,662 - 96,010,578 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	21,037,553 - 21,109,912 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atg4a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624803	8,337,042 - 8,407,222 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624803	8,336,123 - 8,407,354 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003819693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008973104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014343518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034949967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034949968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034949969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000020554 ⟹ ENSPPAP00000004458

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	107,559,639 - 107,623,389 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000020571 ⟹ ENSPPAP00000004461

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	107,593,383 - 107,618,974 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000020591 ⟹ ENSPPAP00000004463

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	107,594,992 - 107,622,423 (+)	Ensembl

RefSeq Acc Id:

XM_003819693 ⟹ XP_003819741

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	107,572,779 - 107,636,591 (+)	NCBI
NHGRI_mPanPan1	X	107,576,420 - 107,640,195 (+)	NCBI
Mhudiblu_PPA_v0	X	97,189,556 - 97,253,371 (+)	NCBI
PanPan1.1	X	107,559,639 - 107,623,389 (+)	NCBI

Sequence:

show sequence

GGGAGTTGCAGTTTGAGAGCAGTTCCGGGCAGGGAGGCGCCTTTGCTGCCCTCACAGACTTGGC
CCCTAGCAGTGCAGAACTACAAGTCCCAGGGATCCTAGCGACCGTCCGTCCGTAGTCAAGTTGC
CGGTGGAATTGGCCCAGGATGACAGCTGGAGAATGGAGTCAGTTTTATCCAAGTATGAAGATCA
GATTACTATTTTCACTGACTACCTAGAAGAATATCCAGATACAGATGAGCTGGTATGGATCTTA
GGGAAGCAGCATCTCCTTAAAACAGAAAAATCTAAGCTGTTGTCTGATATAAGTGCTCGTCTAT
GGTTTACATACAGAAGGAAATTTTCACCAATTGGTGGAACGGGCCCTTCATCAGATGCTGGTTG
GGGATGTATGCTACGCTGTGGACAGATGATGCTGGCTCAAGCCCTTATCTGTAGACACTTGGGA
AGGGACTGGAGCTGGGAGAAACAAAAAGAACAACCCAAAGAATACCAACGCATCCTACAGTGCT
TCTTAGATAGAAAAGATTGTTGCTACTCTATCCATCAAATGGCACAAATGGGTGTAGGAGAAGG
GAAATCAATTGGAGAATGGTTTGGACCAAATACAGTTGCACAGGTGTTAAAAAAACTTGCTTTA
TTTGACGAATGGAATTCCTTGGCTGTTTATGTTTCAATGGATAACACAGTGGTCATTGAAGATA
TCAAAAAAATGTGCCGTGTCCTTCCCTTGAGTGCTGACACACCTGGTGACAGGCCTCCCGATTC
TTTAACTGCTTCAAACCAGAGTAAGGGCACCTCTGCCTACTGCTCAGCCTGGAAACCCCTGCTG
CTCATTGTGCCCCTTCGCCTGGGCATAAACCAAATCAATCCTGTCTATGTTGATGCATTCAAAG
AGTGTTTTAAGATGCCACAGTCTTTAGGGGCATTAGGAGGAAAACCAAATAACGCGTATTATTT
CATAGGATTCTTAGGTGACGAGCTCATCTTCTTGGACCCTCACACAACCCAGACCTTTGTTGAC
ACTGAAGAGAATGGAACGGTTAATGACCAGACTTTCCATTGCCTGCAGTCCCCACAGCGAATGA
ACATCCTAAACCTGGATCCTTCAGTTGCATTGGGATTTTTCTGCAAAGAAGAAAAAGACTTTGA
TAACTGGTGTAGCCTTGTTCAGAAGGAAATTCTAAAGGAGAATTTAAGGATGTTTGAATTAGTT
CAGAAACATCCATCACACTGGCCTCCCTTTGTACCTCCAGCCAAGCCAGAAGTGACAACCACTG
GGGCAGAATTCATTGACTCTACTGAACAACTGGAGGAGTTTGATCTGGAGGAAGATTTTGAGAT
TCTGAGTGTGTAGAATCCTGGGAACGCAACTTGAAGGTCTGTCTTCCATCTGGCACCATAAAAA
CATGAACTTATTGCATAAAACTTTTCTAGTCAGCAAGTGCCTGATATGCCAATAGCATACAAAC
TCAATAGCAATCATGACTGAGCCAATCACTGTTTCTCAGAAAAACAAAACAAAACAAAACAAAT
GACAGTAACCTTTCCCCGGAAAGAAATAGAACAATCATGGAGCCTAGGAGCAGAGAGATGAGGA
GGAGTTCATTGCTTCCCAGCTTGTGTTATATGGCTACAGCAAGTCTTCAGCTGCTGCAATGAGG
AAATGGGCATCTGGAAGACAAACAGCAACTCTCAGCTTGCTTCAAGCACCAGCAGATAAGAGAT
GGTTAAGCTGTTCTTCACCCTTTCAGATGTGACCTCTTTTGGACTAAATACTAAGCAGCAATCT
GTTCTCTTGCTCAAATAATAAAGTGACTGAATCAGGGAGGAAAAGGTTCTTGTTAAATTATTTG
ATTGTGTAGTTGAAGTAATTATAATTTATATCAAAACGTTTGTCAAAGAAACGATGTCAAATAT
ACACTTCTTGATCTCCCTTCTGTTTGCGGGAATCTTACTATTTGATGGGTCACTGTCCCCATTC
TTACTGATACTTTTGTCAGATATCACCCTGTCCTTAAATCATGATCACTTAAATCAGGGGTCAG
CAAACTTTTTCTGTAAAGGGCCAGACAGTAAATATTTTGGGCTTTGCAGGCCATGCGGCCTCTG
TCACATCTACTCAACTCTGCTGTTGACATGCAAAAGCAGCAATAGACAATATGCCTGTAAATGA
GCGTGGCTGTAATCCAAGAAAACTTTATTTACAAAAGCAGGTGGAGGGCTGGGTTTGGCCTGCA
GGCTGTAGCTTGCCAATCAGTGACTTAAATTGTTGATTTTTGTTTGATAAATTAAAAATAAATT
GTGTTTGAAGTATACCCTA

hide sequence

RefSeq Acc Id:

XM_008973104 ⟹ XP_008971352

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	107,572,914 - 107,636,591 (+)	NCBI
NHGRI_mPanPan1	X	107,576,518 - 107,640,195 (+)	NCBI
Mhudiblu_PPA_v0	X	97,189,556 - 97,253,371 (+)	NCBI
PanPan1.1	X	107,559,639 - 107,623,389 (+)	NCBI

Sequence:

show sequence

GGGAGTTGCAGTTTGAGAGCAGTTCCGGGCAGGGAGGCGCCTTTGCTGCCCTCACAGACTTGGC
CCCTAGCAGTGCAGAACTACAAGTCCCAGGGATCCTAGCGACCGTCCGTCCGTAGTCAAGTTGC
CGGTGGAATTGGCCCAGGATGACAGCTGGAGAATGGAGTCAGGTACGGGGAGCGGCTTTGAGTG
GAACCGTGTGAAAGAGCCGGGTTTTATCCAAGTATGAAGATCAGATTACTATTTTCACTGACTA
CCTAGAAGAATATCCAGATACAGATGAGCTGGTATGGATCTTAGGGAAGCAGCATCTCCTTAAA
ACAGAAAAATCTAAGCTGTTGTCTGATATAAGTGCTCGTCTATGGTTTACATACAGAAGGAAAT
TTTCACCAATTGGTGGAACGGGCCCTTCATCAGATGCTGGTTGGGGATGTATGCTACGCTGTGG
ACAGATGATGCTGGCTCAAGCCCTTATCTGTAGACACTTGGGAAGGGACTGGAGCTGGGAGAAA
CAAAAAGAACAACCCAAAGAATACCAACGCATCCTACAGTGCTTCTTAGATAGAAAAGATTGTT
GCTACTCTATCCATCAAATGGCACAAATGGGTGTAGGAGAAGGGAAATCAATTGGAGAATGGTT
TGGACCAAATACAGTTGCACAGGTGTTAAAAAAACTTGCTTTATTTGACGAATGGAATTCCTTG
GCTGTTTATGTTTCAATGGATAACACAGTGGTCATTGAAGATATCAAAAAAATGTGCCGTGTCC
TTCCCTTGAGTGCTGACACACCTGGTGACAGGCCTCCCGATTCTTTAACTGCTTCAAACCAGAG
TAAGGGCACCTCTGCCTACTGCTCAGCCTGGAAACCCCTGCTGCTCATTGTGCCCCTTCGCCTG
GGCATAAACCAAATCAATCCTGTCTATGTTGATGCATTCAAAGAGTGTTTTAAGATGCCACAGT
CTTTAGGGGCATTAGGAGGAAAACCAAATAACGCGTATTATTTCATAGGATTCTTAGGTGACGA
GCTCATCTTCTTGGACCCTCACACAACCCAGACCTTTGTTGACACTGAAGAGAATGGAACGGTT
AATGACCAGACTTTCCATTGCCTGCAGTCCCCACAGCGAATGAACATCCTAAACCTGGATCCTT
CAGTTGCATTGGGATTTTTCTGCAAAGAAGAAAAAGACTTTGATAACTGGTGTAGCCTTGTTCA
GAAGGAAATTCTAAAGGAGAATTTAAGGATGTTTGAATTAGTTCAGAAACATCCATCACACTGG
CCTCCCTTTGTACCTCCAGCCAAGCCAGAAGTGACAACCACTGGGGCAGAATTCATTGACTCTA
CTGAACAACTGGAGGAGTTTGATCTGGAGGAAGATTTTGAGATTCTGAGTGTGTAGAATCCTGG
GAACGCAACTTGAAGGTCTGTCTTCCATCTGGCACCATAAAAACATGAACTTATTGCATAAAAC
TTTTCTAGTCAGCAAGTGCCTGATATGCCAATAGCATACAAACTCAATAGCAATCATGACTGAG
CCAATCACTGTTTCTCAGAAAAACAAAACAAAACAAAACAAATGACAGTAACCTTTCCCCGGAA
AGAAATAGAACAATCATGGAGCCTAGGAGCAGAGAGATGAGGAGGAGTTCATTGCTTCCCAGCT
TGTGTTATATGGCTACAGCAAGTCTTCAGCTGCTGCAATGAGGAAATGGGCATCTGGAAGACAA
ACAGCAACTCTCAGCTTGCTTCAAGCACCAGCAGATAAGAGATGGTTAAGCTGTTCTTCACCCT
TTCAGATGTGACCTCTTTTGGACTAAATACTAAGCAGCAATCTGTTCTCTTGCTCAAATAATAA
AGTGACTGAATCAGGGAGGAAAAGGTTCTTGTTAAATTATTTGATTGTGTAGTTGAAGTAATTA
TAATTTATATCAAAACGTTTGTCAAAGAAACGATGTCAAATATACACTTCTTGATCTCCCTTCT
GTTTGCGGGAATCTTACTATTTGATGGGTCACTGTCCCCATTCTTACTGATACTTTTGTCAGAT
ATCACCCTGTCCTTAAATCATGATCACTTAAATCAGGGGTCAGCAAACTTTTTCTGTAAAGGGC
CAGACAGTAAATATTTTGGGCTTTGCAGGCCATGCGGCCTCTGTCACATCTACTCAACTCTGCT
GTTGACATGCAAAAGCAGCAATAGACAATATGCCTGTAAATGAGCGTGGCTGTAATCCAAGAAA
ACTTTATTTACAAAAGCAGGTGGAGGGCTGGGTTTGGCCTGCAGGCTGTAGCTTGCCAATCAGT
GACTTAAATTGTTGATTTTTGTTTGATAAATTAAAAATAAATTGTGTTTGAAGTATACCCTA

hide sequence

RefSeq Acc Id:

XM_034949967 ⟹ XP_034805858

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	107,572,806 - 107,636,591 (+)	NCBI
NHGRI_mPanPan1	X	107,576,410 - 107,640,195 (+)	NCBI
Mhudiblu_PPA_v0	X	97,189,586 - 97,253,371 (+)	NCBI

RefSeq Acc Id:

XM_034949968 ⟹ XP_034805859

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	107,572,914 - 107,636,591 (+)	NCBI
NHGRI_mPanPan1	X	107,576,518 - 107,640,195 (+)	NCBI
Mhudiblu_PPA_v0	X	97,189,672 - 97,253,371 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003819741	(Get FASTA)	NCBI Sequence Viewer
	XP_008971352	(Get FASTA)	NCBI Sequence Viewer
	XP_034805858	(Get FASTA)	NCBI Sequence Viewer
	XP_034805859	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000004458
	ENSPPAP00000004458.1
	ENSPPAP00000004461.1
	ENSPPAP00000004463.1

RefSeq Acc Id:	XP_003819741 ⟸ XM_003819693
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZNT9 (UniProtKB/TrEMBL), A0A2R8ZNU4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPI GGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSI HQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLS ADTPGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGA LGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVAL GFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQL EEFDLEEDFEILSV hide sequence

RefSeq Acc Id:

XP_008971352 ⟸ XM_008973104

- Peptide Label:

isoform X3

- Sequence:

show sequence

MLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKS
IGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTPGDRPPDSLT
ASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIG
FLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNW
CSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILS
V

hide sequence

RefSeq Acc Id:	XP_034805858 ⟸ XM_034949967
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8ZNU4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034805859 ⟸ XM_034949968
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSPPAP00000004458 ⟸ ENSPPAT00000020554

Ensembl Acc Id:

ENSPPAP00000004463 ⟸ ENSPPAT00000020591

Ensembl Acc Id:

ENSPPAP00000004461 ⟸ ENSPPAT00000020571

Protein Domains

Peptidase C54 catalytic

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000018771	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000020554.1	UniProtKB/TrEMBL
	ENSPPAT00000020571.1	UniProtKB/TrEMBL
	ENSPPAT00000020591.1	UniProtKB/TrEMBL
InterPro	ATG4_LIR	UniProtKB/TrEMBL
	Papain-like_cys_pep_sf	UniProtKB/TrEMBL
	Peptidase_C54	UniProtKB/TrEMBL
	Peptidase_C54_cat	UniProtKB/TrEMBL
KEGG Report	pps:100985006	UniProtKB/TrEMBL
NCBI Gene	ATG4A	ENTREZGENE
PANTHER	PTHR22624	UniProtKB/TrEMBL
	PTHR22624:SF35	UniProtKB/TrEMBL
Pfam	ATG4_LIR	UniProtKB/TrEMBL
	Peptidase_C54	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54001	UniProtKB/TrEMBL
UniProt	A0A2R8ZI77_PANPA	UniProtKB/TrEMBL
	A0A2R8ZNT9	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R8ZNU4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations