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ONTOLOGY REPORT - ANNOTATIONS

Term:signal peptide processing
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Accession:GO:0006465 term browser browse the term
Definition:The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
Synonyms:exact_synonym: leader peptide processing
 xref: Reactome:R-HSA-159782 "Removal of aminoterminal propeptides from gamma-carboxylated proteins"


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signal peptide processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arxes1 adipocyte-related X-chromosome expressed sequence 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:98,950,530...98,952,049 JBrowse link
G Arxes2 adipocyte-related X-chromosome expressed sequence 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:98,985,844...98,987,425 JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:20052765) RGD PMID:20052765 NCBI chr15:79,893,573...79,903,438 JBrowse link
G ENSRNOG00000068334 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO
IEA		 (PMID:16912035)
GO_REF:0000107
(PMID:26416966)		 RGD
Ensembl		 PMID:16912035 PMID:26416966 GO_REF:0000107 NCBI chr 1:143,757,389...143,770,430 JBrowse link
G Hm13 histocompatibility minor 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:141,145,792...141,183,557 JBrowse link
G Immp1l inner mitochondrial membrane peptidase subunit 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:92,385,329...92,449,559 JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:58,070,035...58,970,165 JBrowse link
G Mcts2 MCTS family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:141,163,330...141,164,108 JBrowse link
G Parl presenilin associated, rhomboid-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:80,594,059...80,620,506 JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 involved_in ISO (PMID:16912035) RGD PMID:16912035 NCBI chr 1:214,837,847...215,267,626 JBrowse link
G Sec11a SEC11 homolog A, signal peptidase complex subunit involved_in ISO
ISS
IEA
IBA		 (PMID:34388369)
GO_REF:0000024
GO_REF:0000104
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:34388369 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:134,881,448...134,909,427 JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit involved_in IEA
ISO
ISS
IBA		 GO_REF:0000104
(PMID:34388369)
GO_REF:0000024
GO_REF:0000002
GO_REF:0000033		 UniProt
RGD
InterPro
GO_Central		 PMID:34388369 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr18:61,590,905...61,607,247 JBrowse link
G Spcs1 signal peptidase complex subunit 1 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr16:6,190,208...6,191,776 JBrowse link
G Spcs2 signal peptidase complex subunit 2 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr 1:154,163,724...154,183,152 JBrowse link
G Spcs3 signal peptidase complex subunit 3 involved_in ISO
IBA		 (PMID:34388369)
GO_REF:0000033		 RGD
GO_Central		 PMID:34388369 GO_REF:0000033 NCBI chr16:37,305,358...37,310,792 JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:41,515,635...41,600,079 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      metabolic process 12157
        macromolecule metabolic process 9981
          protein metabolic process 5231
            protein maturation 625
              protein processing 259
                signal peptide processing 17
                  SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 0
Path 2
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      metabolic process 12157
        biosynthetic process 8641
          macromolecule biosynthetic process 7653
            gene expression 7211
              protein maturation 625
                protein processing 259
                  signal peptide processing 17
                    SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 0
paths to the root