LGMN (legumain) - Rat Genome Database

Name: LGMN
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: LGMN (legumain) Pan paniscus

Analyze

Symbol:

LGMN

Name:

legumain

RGD ID:

11893195

Description:

ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); cysteine-type peptidase activity (inferred); endopeptidase activator activity (inferred); INVOLVED IN associative learning (ortholog); dendritic spine organization (ortholog); memory (ortholog); ASSOCIATED WITH achondrogenesis type IA (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN apical part of cell (ortholog); late endosome (ortholog); lysosomal lumen (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LGMN (legumain)	NCBI	Ortholog
Mus musculus (house mouse):	Lgmn (legumain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Lgmn (legumain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lgmn (legumain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LGMN (legumain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lgmn (legumain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LGMN (legumain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LGMN (legumain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lgmn (legumain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	93,861,233 - 93,907,416 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	93,077,738 - 93,123,921 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	73,337,607 - 73,383,462 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	92,677,608 - 92,723,051 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	92,677,608 - 92,723,051 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

achondrogenesis type IA (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

High Myopia (ISO)

lymphatic system disease (ISO)

Orthomyxoviridae Infections (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antigen processing and presentation of exogenous peptide antigen via MHC class II (IEA)

associative learning (ISO)

cellular response to amyloid-beta (IEA)

cellular response to calcium ion (IEA)

cellular response to hepatocyte growth factor stimulus (IEA)

dendritic spine organization (ISO)

memory (ISO)

negative regulation of ERBB signaling pathway (ISO)

negative regulation of gene expression (IEA)

negative regulation of multicellular organism growth (ISO)

negative regulation of neuron apoptotic process (IEA,ISO)

positive regulation of cell population proliferation (IEA)

positive regulation of endothelial cell chemotaxis (IEA)

positive regulation of long-term synaptic potentiation (ISO)

positive regulation of mitotic cell cycle (IEA)

positive regulation of monocyte chemotaxis (IEA)

protein maturation (ISO)

proteolysis (IEA,ISO)

proteolysis involved in protein catabolic process (IEA)

receptor catabolic process (ISO)

renal system process (ISO)

response to acidic pH (IEA,ISO)

self proteolysis (IEA)

vacuolar protein processing (IEA)

Cellular Component

apical part of cell (ISO)

cytoplasm (IEA)

extracellular region (IEA)

late endosome (ISO)

lysosomal lumen (IEA,ISO)

lysosome (ISO)

perinuclear region of cytoplasm (IEA)

vacuole (IEA)

Molecular Function

cysteine-type endopeptidase activity (IEA)

cysteine-type peptidase activity (IEA)

endopeptidase activator activity (IEA)

endopeptidase activity (IEA)

peptidase activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LGMN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	93,861,233 - 93,907,416 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	93,077,738 - 93,123,921 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	73,337,607 - 73,383,462 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	92,677,608 - 92,723,051 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	92,677,608 - 92,723,051 (-)	Ensembl	panpan1.1		panPan2

LGMN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	92,703,809 - 92,748,627 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	92,703,807 - 92,748,679 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	93,170,154 - 93,214,972 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	92,239,907 - 92,284,765 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	92,239,909 - 92,284,765	NCBI
Celera	14	73,224,285 - 73,269,160 (-)	NCBI		Celera
Cytogenetic Map	14	q32.12	NCBI
HuRef	14	73,353,202 - 73,398,165 (-)	NCBI		HuRef
CHM1_1	14	93,108,397 - 93,153,238 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	86,935,604 - 86,980,392 (-)	NCBI		T2T-CHM13v2.0

Lgmn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	102,360,341 - 102,405,987 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	102,360,343 - 102,406,072 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	102,394,082 - 102,439,728 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	102,394,084 - 102,439,813 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	103,632,308 - 103,677,907 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	102,795,148 - 102,840,747 (-)	NCBI		MGSCv36	mm8
Celera	12	103,611,726 - 103,647,892 (-)	NCBI		Celera
Cytogenetic Map	12	E	NCBI
cM Map	12	51.45	NCBI

Lgmn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	127,308,913 - 127,347,355 (-)	NCBI		GRCr8
mRatBN7.2	6	121,544,048 - 121,582,495 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	121,544,053 - 121,582,480 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	121,684,520 - 121,722,056 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	121,979,783 - 122,017,312 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	121,315,105 - 121,353,227 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	126,282,246 - 126,308,207 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	126,282,233 - 126,320,726 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	135,492,943 - 135,518,916 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	126,668,905 - 126,694,866 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	126,672,651 - 126,698,616 (-)	NCBI
Celera	6	119,032,612 - 119,058,582 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

Lgmn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	14,905,856 - 14,939,256 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	14,905,856 - 14,938,722 (-)	NCBI	ChiLan1.0	ChiLan1.0

LGMN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	1,810,263 - 1,843,116 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	1,728,273 - 1,843,050 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	1,834,051 - 1,866,767 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	1,864,425 - 1,878,822 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	1,782,672 - 1,889,344 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	1,802,050 - 1,834,797 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	1,752,395 - 1,785,146 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	1,879,451 - 1,912,213 (-)	NCBI		UU_Cfam_GSD_1.0

Lgmn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	12,674,224 - 12,694,251 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936733	772,708 - 792,995 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936733	772,764 - 792,792 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LGMN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	114,173,693 - 114,217,102 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	114,176,217 - 114,210,096 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	120,780,926 - 120,811,668 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LGMN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	70,456,463 - 70,500,345 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	70,456,095 - 70,486,087 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	57,705,088 - 57,748,692 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lgmn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	9,204,790 - 9,240,309 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	9,207,496 - 9,240,026 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003832785	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008958213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000054510 ⟹ ENSPPAP00000031644

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	14	92,677,608 - 92,723,051 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000054516 ⟹ ENSPPAP00000031651

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	14	92,678,067 - 92,707,255 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000054521 ⟹ ENSPPAP00000031656

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	14	92,678,123 - 92,707,255 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000054527 ⟹ ENSPPAP00000031662

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	14	92,688,179 - 92,707,255 (-)	Ensembl

RefSeq Acc Id:

XM_003832785 ⟹ XP_003832833

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	93,861,233 - 93,907,416 (-)	NCBI
NHGRI_mPanPan1	14	93,077,738 - 93,123,921 (-)	NCBI
Mhudiblu_PPA_v0	14	73,337,607 - 73,383,446 (-)	NCBI
PanPan1.1	14	92,677,608 - 92,723,051 (-)	NCBI

Sequence:

show sequence

AGATGCCACGCCCCATAGCTCCACCAGTCACCGCGGCACAGTGGCCCTTAAGCGAGGAGCGGCG
GCGCCCGCAGCAATCACAGCAGTGCGGCCGTCGTGGGTGTTTGGTGTGAGGCTGCGCGCCGCCG
CGAGTTCTCACGGTCCCGCCGGCGCCACCACCGCGGTCACTCACTGCCGCCGCCGCCACCACTG
CCACCACGGTCGCCTGCCACAGGTTTCTGCAATTGAACTCCAAGGTGCAGAATGGTTTGGAAAG
TAGCTGTATTCCTCAGTGTGGCCCTGGGCATTGGTGCTGTTCCTATAGATGATCCTGAAGATGG
AGGCAAGCACTGGGTGGTGATCGTGGCGGGTTCAAATGGCTGGTATAATTATAGGCACCAGGCA
GACGCGTGCCATGCCTACCAGATCATTCACCGCAATGGGATTCCTGACGAACAGATCGTTGTGA
TGATGTACGATGACATCGCTTACTCTGAAGACAATCCCACTCCAGGAATTGTGATCAACAGGCC
CAATGGCACAGATGTCTATCAGGGAGTCCCGAAGGACTACACCGGAGAGGATGTTACCCCACAA
AATTTCCTTGCTGTGTTGAGAGGCGATGCAGAAGCAGTGAAGGGCATAGGATCCGGCAAAGTCC
TGAAGAGCGGCCCCCAGGATCACGTGTTCATTTACTTCACTGACCATGGATCTACTGGAATACT
GGTTTTTCCCAATGAAGATCTTCACGTAAAGGACCTGAATGAGACCATCCATTACATGTACAAA
CACAAAATGTACCGAAAGATGGTGTTCTACATTGAAGCCTGTGAGTCTGGGTCCATGATGAACC
ACCTGCCGGATAACATCAATGTTTATGCAACTACTGCTGCCAACCCCAGAGAGTCGTCCTACGC
CTGTTACTATGATGAGAAGAGGTCCACGTACCTGGGGGACTGGTACAGCGTCAACTGGATGGAA
GACTCGGACGTGGAAGATCTGACTAAAGAGACCCTGCACAAGCAGTACCACCTGGTAAAATCGC
ACACCAACACCAGCCACGTCATGCAGTATGGAAACAAAACAATCTCCACCATGAAAGTGATGCA
GTTTCAGGGTATGAAACACAAAGCCAGTTCTCCTATCTCCCTACCTCCAGTCACACACCTTGAC
CTCACCCCCAGCCCTGATGTGCCTCTCACCATCATGAAAAGGAAACTGATGAACACCAATGATC
TGGAGGAGTCCAGGCAGCTCACAGAGGAGATCCAGCGGCATCTGGATGCCAGGCACCTCATTGA
GAAGTCAGTGCGCAAGATCGTCTCCTTGCTGGCAGCGTCCGAGGCTGAGGTGGAGCAGCTCCTG
TCCGAGAGAGCCCCGCTCACGGGGCACAGCTGCTACCCAGAGGCCCTGCTGCACTTCCGGACCC
ACTGCTTCAACTGGCACTCCCCCACGTACGAGTATGCGTTGAGACATTTGTACGTGCTGGTCAA
CCTTTGTGAGAAGCCGTATCCGCTTCACAGGATAAAATTGTCCATGGACCACGTGTGCCTTGGT
CACTACTGAAGAGCTGCCTCCTGGAAGCTTTTCCAAGTGTGAGCGCCCCACCGACTGTGTGCTG
ATCAGAGACTGGAGAGGTGGAGTGAGAAGTCTCCGCTGCTCGGGCCCTCCTGGGGAGCCCCCGC
TCCAGGGCTCGCTCCAGGACCTTCTTCACAAGATGACTTGCTCGCTGTTACCTACTTCCCCAGT
CTTTTCTGAAAAACTACAAATTGGGGTGGGAAAAGCTCTGTATTGAGAAGGGTCACATTTGCTT
TCTAGGAGGTTTGTTGTTTTGTTTTGCCTGTTAGTTTTGAGGAGCAGGAAGCTCATGGGGGCTT
CTGTAGCCCCTCTCAAAAGGAGTCTTTATTCTGAGAATTTGAAGCCGAAACCTCTTTAAATCTT
CAGAATGATTTTATTGAAGAGGGCCGCAAGCCCCAAATGGAAAACTGTTTTTAGAAAATATGAT
GATTTTTGATTGCTTTTGTATTTAATTCTGCAGGTGTTCAAGTCTTAAAAAATAAAGGTTTATA
ACAGAACCCAAA

hide sequence

RefSeq Acc Id:

XM_008958213 ⟹ XP_008956461

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	93,861,233 - 93,907,116 (-)	NCBI
NHGRI_mPanPan1	14	93,077,738 - 93,123,621 (-)	NCBI
Mhudiblu_PPA_v0	14	73,337,607 - 73,383,462 (-)	NCBI
PanPan1.1	14	92,677,608 - 92,723,019 (-)	NCBI

Sequence:

show sequence

GCGGCACAGTGGCCCTTAAGCGAGGAGCGGCGGCGCCCGCAGCAATCACAGCAGTGCGGCCGTC
GTGGGTGTTTGGTGTGAGGCTGCGCGCCGCCGCGAGTTCTCACGGTCCCGCCGGCGCCACCACC
GCGGTCACTCACTGCCGCCGCCGCCACCACTGCCACCACGGTCGCCTGCCACAGGTTTCTGCAA
TTGAACTCCAAGGTGCAGAATGGTTTGGAAAGTAGCTGTATTCCTCAGTGTGGCCCTGGGCATT
GGTGCTGTTCCTATAGATGATCCTGAAGATGGAGGCAAGCACTGGGTGGTGATCGTGGCGGGTT
CAAATGGCTGGTATAATTATAGGCACCAGGCAGACGCGTGCCATGCCTACCAGATCATTCACCG
CAATGGGATTCCTGACGAACAGATCGTTGTGATGATGTACGATGACATCGCTTACTCTGAAGAC
AATCCCACTCCAGGAATTGTGATCAACAGGCCCAATGGCACAGATGTCTATCAGGGAGTCCCGA
AGGACTACACCGGAGAGGATGTTACCCCACAAAATTTCCTTGCTGTGTTGAGAGGCGATGCAGA
AGCAGTGAAGGGCATAGGATCCGGCAAAGTCCTGAAGAGCGGCCCCCAGGATCACGTGTTCATT
TACTTCACTGACCATGGATCTACTGGAATACTGGTTTTTCCCAATGAAGATCTTCACGTAAAGG
ACCTGAATGAGACCATCCATTACATGTACAAACACAAAATGTACCGAAAGATGGTGTTCTACAT
TGAAGCCTGTGAGTCTGGGTCCATGATGAACCACCTGCCGGATAACATCAATGTTTATGCAACT
ACTGCTGCCAACCCCAGAGAGTCGTCCTACGCCTGTTACTATGATGAGAAGAGGTCCACGTACC
TGGGGGACTGGTACAGCGTCAACTGGATGGAAGACTCGGACGTGGAAGATCTGACTAAAGAGAC
CCTGCACAAGCAGTACCACCTGGTAAAATCGCACACCAACACCAGCCACGTCATGCAGTATGGA
AACAAAACAATCTCCACCATGAAAGTGATGCAGTTTCAGGGTATGAAACACAAAGCCAGTTCTC
CTATCTCCCTACCTCCAGTCACACACCTTGACCTCACCCCCAGCCCTGATGTGCCTCTCACCAT
CATGAAAAGGAAACTGATGAACACCAATGATCTGGAGGAGTCCAGGCAGCTCACAGAGGAGATC
CAGCGGCATCTGGATGCCAGGCACCTCATTGAGAAGTCAGTGCGCAAGATCGTCTCCTTGCTGG
CAGCGTCCGAGGCTGAGGTGGAGCAGCTCCTGTCCGAGAGAGCCCCGCTCACGGGGCACAGCTG
CTACCCAGAGGCCCTGCTGCACTTCCGGACCCACTGCTTCAACTGGCACTCCCCCACGGATAAA
ATTGTCCATGGACCACGTGTGCCTTGGTCACTACTGAAGAGCTGCCTCCTGGAAGCTTTTCCAA
GTGTGAGCGCCCCACCGACTGTGTGCTGATCAGAGACTGGAGAGGTGGAGTGAGAAGTCTCCGC
TGCTCGGGCCCTCCTGGGGAGCCCCCGCTCCAGGGCTCGCTCCAGGACCTTCTTCACAAGATGA
CTTGCTCGCTGTTACCTACTTCCCCAGTCTTTTCTGAAAAACTACAAATTGGGGTGGGAAAAGC
TCTGTATTGAGAAGGGTCACATTTGCTTTCTAGGAGGTTTGTTGTTTTGTTTTGCCTGTTAGTT
TTGAGGAGCAGGAAGCTCATGGGGGCTTCTGTAGCCCCTCTCAAAAGGAGTCTTTATTCTGAGA
ATTTGAAGCCGAAACCTCTTTAAATCTTCAGAATGATTTTATTGAAGAGGGCCGCAAGCCCCAA
ATGGAAAACTGTTTTTAGAAAATATGATGATTTTTGATTGCTTTTGTATTTAATTCTGCAGGTG
TTCAAGTCTTAAAAAATAAAGGTTTATAACAGAACCCAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003832833	(Get FASTA)	NCBI Sequence Viewer
	XP_008956461	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000031644
	ENSPPAP00000031644.1
	ENSPPAP00000031651
	ENSPPAP00000031651.1
	ENSPPAP00000031656.1
	ENSPPAP00000031662.1

RefSeq Acc Id:

XP_008956461 ⟸ XM_008958213

- Peptide Label:

isoform X2

- Sequence:

show sequence

MVWKVAVFLSVALGIGAVPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDE
QIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIG
SGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESG
SMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYH
LVKSHTNTSHVMQYGNKTISTMKVMQFQGMKHKASSPISLPPVTHLDLTPSPDVPLTIMKRKLM
NTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALL
HFRTHCFNWHSPTDKIVHGPRVPWSLLKSCLLEAFPSVSAPPTVC

hide sequence

RefSeq Acc Id:	XP_003832833 ⟸ XM_003832785
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BQF5 (UniProtKB/TrEMBL), A0A2R9BPS2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVWKVAVFLSVALGIGAVPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDE QIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIG SGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESG SMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYH LVKSHTNTSHVMQYGNKTISTMKVMQFQGMKHKASSPISLPPVTHLDLTPSPDVPLTIMKRKLM NTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALL HFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY hide sequence

RefSeq Acc Id:

ENSPPAP00000031644 ⟸ ENSPPAT00000054510

RefSeq Acc Id:

ENSPPAP00000031651 ⟸ ENSPPAT00000054516

RefSeq Acc Id:

ENSPPAP00000031656 ⟸ ENSPPAT00000054521

RefSeq Acc Id:

ENSPPAP00000031662 ⟸ ENSPPAT00000054527

Protein Domains

Legumain prodomain

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000038740	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000054510.1	UniProtKB/TrEMBL
	ENSPPAT00000054516.1	UniProtKB/TrEMBL
	ENSPPAT00000054521.1	UniProtKB/TrEMBL
	ENSPPAT00000054527.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.132.130	UniProtKB/TrEMBL
	3.40.50.1460	UniProtKB/TrEMBL
InterPro	IPR043577	UniProtKB/TrEMBL
	Legum_prodom	UniProtKB/TrEMBL
	Legumain_prodom_sf	UniProtKB/TrEMBL
	Peptidase_C13	UniProtKB/TrEMBL
KEGG Report	pps:100979480	UniProtKB/TrEMBL
NCBI Gene	LGMN	ENTREZGENE
PANTHER	LEGUMAIN	UniProtKB/TrEMBL
	PTHR12000	UniProtKB/TrEMBL
Pfam	Legum_prodom	UniProtKB/TrEMBL
	Peptidase_C13	UniProtKB/TrEMBL
PIRSF	Legumain	UniProtKB/TrEMBL
	PIRSF500139	UniProtKB/TrEMBL
PRINTS	HEMOGLOBNASE	UniProtKB/TrEMBL
UniProt	A0A2R9BPR8_PANPA	UniProtKB/TrEMBL
	A0A2R9BPS2	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BQF5	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BYR8_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI