BMP1 (bone morphogenetic protein 1) - Rat Genome Database

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Gene: BMP1 (bone morphogenetic protein 1) Pan paniscus
Analyze
Symbol: BMP1
Name: bone morphogenetic protein 1
RGD ID: 11905341
Description: ENCODES a protein that exhibits calcium ion binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN positive regulation of cartilage development (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); Conotruncal Cardiac Defects (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,666,831 - 40,714,042 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,392,228 - 16,439,248 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,410,139 - 21,457,144 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,349,836 - 18,396,796 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,349,836 - 18,396,796 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
extracellular space  (IEA,ISO)
vesicle  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BMP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,666,831 - 40,714,042 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,392,228 - 16,439,248 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,410,139 - 21,457,144 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,349,836 - 18,396,796 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,349,836 - 18,396,796 (+)Ensemblpanpan1.1panPan2
BMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,165,372 - 22,212,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,165,140 - 22,212,326 (+)EnsemblGRCh38hg38GRCh38
GRCh37822,022,885 - 22,069,839 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,078,835 - 22,125,782 (+)NCBINCBI36Build 36hg18NCBI36
Celera820,984,783 - 21,032,542 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,564,967 - 20,612,031 (+)NCBIHuRef
CHM1_1822,224,312 - 22,271,500 (+)NCBICHM1_1
T2T-CHM13v2.0822,439,316 - 22,486,280 (+)NCBIT2T-CHM13v2.0
Bmp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,711,998 - 70,758,280 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,711,998 - 70,757,674 (-)EnsemblGRCm39 Ensembl
GRCm381470,474,555 - 70,520,716 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,474,558 - 70,520,234 (-)EnsemblGRCm38mm10GRCm38
MGSCv371470,874,362 - 70,920,067 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,209,638 - 69,255,268 (-)NCBIMGSCv36mm8
Celera1468,015,981 - 68,061,716 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
Bmp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,961,310 - 52,005,597 (-)NCBIGRCr8
mRatBN7.21545,551,603 - 45,595,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,551,603 - 45,595,776 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,669,483 - 49,713,645 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,780,998 - 50,825,151 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,640,279 - 47,684,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,166,401 - 52,210,786 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,166,401 - 52,210,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,889,918 - 55,934,263 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,878,144 - 50,922,313 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,910,779 - 50,923,437 (-)NCBI
Celera1545,230,611 - 45,274,179 (-)NCBICelera
Cytogenetic Map15p11NCBI
Bmp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,660,588 - 45,693,724 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,660,591 - 45,693,724 (+)NCBIChiLan1.0ChiLan1.0
BMP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,043,594 - 35,087,282 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,020,751 - 35,087,545 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,633,298 - 35,676,927 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,255,039 - 35,298,679 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,255,044 - 35,298,662 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,200,533 - 35,244,157 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,055,062 - 35,098,676 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,210,570 - 35,254,197 (-)NCBIUU_Cfam_GSD_1.0
Bmp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,546,649 - 12,579,706 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365555,990,836 - 6,023,878 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365555,990,822 - 6,023,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,443,912 - 6,489,063 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,443,773 - 6,489,066 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,881,220 - 6,923,093 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BMP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,234,242 - 20,281,768 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,234,184 - 20,283,467 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605221,954,309 - 22,001,797 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,744,821 - 17,788,510 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,745,344 - 17,788,183 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000022277   ⟹   ENSPPAP00000004859
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl818,349,836 - 18,396,796 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000022280   ⟹   ENSPPAP00000004861
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl818,349,836 - 18,385,959 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000022291   ⟹   ENSPPAP00000004864
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl818,349,951 - 18,362,257 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000022295   ⟹   ENSPPAP00000004865
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl818,349,951 - 18,361,341 (+)Ensembl
RefSeq Acc Id: XM_003823603   ⟹   XP_003823651
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,666,849 - 40,714,042 (+)NCBI
NHGRI_mPanPan1816,392,228 - 16,439,248 (+)NCBI
Mhudiblu_PPA_v0821,410,139 - 21,457,144 (+)NCBI
PanPan1.1818,349,836 - 18,396,796 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008977243   ⟹   XP_008975491
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,666,839 - 40,703,216 (+)NCBI
NHGRI_mPanPan1816,392,228 - 16,428,587 (+)NCBI
Mhudiblu_PPA_v0821,410,139 - 21,446,298 (+)NCBI
PanPan1.1818,349,836 - 18,385,959 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024929869   ⟹   XP_024785637
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,666,831 - 40,703,216 (+)NCBI
NHGRI_mPanPan1816,392,312 - 16,428,587 (+)NCBI
Mhudiblu_PPA_v0821,410,228 - 21,446,298 (+)NCBI
PanPan1.1818,349,836 - 18,385,959 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003823651   ⟸   XM_003823603
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZJF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008975491   ⟸   XM_008977243
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZPX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024785637   ⟸   XM_024929869
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000004864   ⟸   ENSPPAT00000022291
RefSeq Acc Id: ENSPPAP00000004865   ⟸   ENSPPAT00000022295
RefSeq Acc Id: ENSPPAP00000004861   ⟸   ENSPPAT00000022280
RefSeq Acc Id: ENSPPAP00000004859   ⟸   ENSPPAT00000022277
Protein Domains
CUB   EGF-like   Peptidase M12A


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000020298 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000022277.1 UniProtKB/TrEMBL
  ENSPPAT00000022280.1 UniProtKB/TrEMBL
  ENSPPAT00000022291.1 UniProtKB/TrEMBL
  ENSPPAT00000022295.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.290 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro BMP_1/tolloid-like UniProtKB/TrEMBL
  CUB_dom UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12A UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  Sperma_CUB_dom_sf UniProtKB/TrEMBL
  ZnMP_TLD/BMP1 UniProtKB/TrEMBL
KEGG Report pps:100979179 UniProtKB/TrEMBL
NCBI Gene BMP1 ENTREZGENE
PANTHER BONE MORPHOGENETIC PROTEIN 1 UniProtKB/TrEMBL
  BONE MORPHOGENETIC PROTEIN 1 UniProtKB/TrEMBL
  DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING UniProtKB/TrEMBL
  OVOCHYMASE-RELATED UniProtKB/TrEMBL
Pfam Astacin UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  FXa_inhibition UniProtKB/TrEMBL
PIRSF BMP_1/tolloid-like UniProtKB/TrEMBL
PRINTS ASTACIN UniProtKB/TrEMBL
PROSITE ASTACIN UniProtKB/TrEMBL
  ASX_HYDROXYL UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
SMART CUB UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF49854 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A2R8ZJF6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZJJ2_PANPA UniProtKB/TrEMBL
  A0A2R8ZLQ0_PANPA UniProtKB/TrEMBL
  A0A2R8ZPX7 ENTREZGENE, UniProtKB/TrEMBL