CPZ (carboxypeptidase Z) - Rat Genome Database

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Gene: CPZ (carboxypeptidase Z) Pan paniscus
Analyze
Symbol: CPZ
Name: carboxypeptidase Z
RGD ID: 12028021
Description: ENCODES a protein that exhibits metallocarboxypeptidase activity (inferred); zinc ion binding (inferred); INVOLVED IN peptide metabolic process (inferred); protein processing (inferred); proteolysis (inferred); ASSOCIATED WITH Dwarfism (ortholog); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v238,878,662 - 8,907,200 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan148,806,093 - 8,835,503 (+)NCBINHGRI_mPanPan1
PanPan1.148,623,879 - 8,684,722 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl48,656,029 - 8,684,722 (+)Ensemblpanpan1.1panPan2


Disease Annotations     Click to see Annotation Detail View
Dwarfism  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CPZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v238,878,662 - 8,907,200 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan148,806,093 - 8,835,503 (+)NCBINHGRI_mPanPan1
PanPan1.148,623,879 - 8,684,722 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl48,656,029 - 8,684,722 (+)Ensemblpanpan1.1panPan2
CPZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3848,592,765 - 8,619,752 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl48,592,660 - 8,619,759 (+)EnsemblGRCh38hg38GRCh38
GRCh3748,594,492 - 8,621,479 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3648,645,335 - 8,672,388 (+)NCBINCBI36Build 36hg18NCBI36
Build 3448,712,592 - 8,739,547NCBI
Celera48,487,239 - 8,514,366 (+)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef48,513,792 - 8,540,980 (+)NCBIHuRef
CHM1_148,592,625 - 8,619,813 (+)NCBICHM1_1
T2T-CHM13v2.048,572,626 - 8,599,700 (+)NCBIT2T-CHM13v2.0
Cpz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39535,659,562 - 35,682,970 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl535,659,562 - 35,683,042 (-)EnsemblGRCm39 Ensembl
GRCm38535,502,218 - 35,525,626 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl535,502,218 - 35,525,698 (-)EnsemblGRCm38mm10GRCm38
MGSCv37535,844,867 - 35,868,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,819,196 - 35,842,396 (-)NCBIMGSCv36mm8
Celera532,977,576 - 33,000,943 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map518.16NCBI
Cpz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81479,448,242 - 79,471,557 (+)NCBIGRCr8
mRatBN7.21475,223,692 - 75,246,946 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,223,605 - 75,246,945 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1479,677,279 - 79,700,523 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01480,918,147 - 80,941,395 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01477,363,131 - 77,386,387 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01480,402,946 - 80,426,203 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1480,403,001 - 80,426,245 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,028,890 - 80,052,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41480,857,371 - 80,880,592 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11480,859,761 - 80,882,982 (+)NCBI
Celera1474,152,116 - 74,175,339 (+)NCBICelera
Cytogenetic Map14q21NCBI
Cpz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555142,572,173 - 2,586,038 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555142,572,075 - 2,590,274 (-)NCBIChiLan1.0ChiLan1.0
CPZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1360,291,704 - 60,312,551 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl360,297,752 - 60,312,598 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha362,942,106 - 62,964,158 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0360,767,264 - 60,789,341 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl360,772,327 - 60,789,341 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1360,261,876 - 60,283,927 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0360,466,687 - 60,488,752 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0360,822,705 - 60,844,819 (+)NCBIUU_Cfam_GSD_1.0
Cpz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528566,100,353 - 66,123,380 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647719,801,698 - 19,825,256 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647719,792,738 - 19,825,066 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl82,620,768 - 2,642,524 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.182,620,765 - 2,642,524 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CPZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12744,516,632 - 44,546,475 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2744,516,800 - 44,546,337 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666051842,345 - 872,472 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475524,075,939 - 24,088,088 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475524,069,650 - 24,088,180 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000049098   ⟹   ENSPPAP00000026265
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl48,656,029 - 8,684,722 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000049106   ⟹   ENSPPAP00000026273
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl48,656,029 - 8,684,722 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000049110   ⟹   ENSPPAP00000026277
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl48,656,852 - 8,684,722 (+)Ensembl
RefSeq Acc Id: XM_034951915   ⟹   XP_034807806
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v238,878,662 - 8,907,200 (+)NCBI
NHGRI_mPanPan148,806,093 - 8,835,503 (+)NCBI
RefSeq Acc Id: XM_034951916   ⟹   XP_034807807
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v238,878,744 - 8,907,200 (+)NCBI
NHGRI_mPanPan148,806,110 - 8,835,503 (+)NCBI
RefSeq Acc Id: XM_034951917   ⟹   XP_034807808
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v238,878,731 - 8,907,200 (+)NCBI
NHGRI_mPanPan148,806,110 - 8,835,503 (+)NCBI
RefSeq Acc Id: XM_063603718   ⟹   XP_063459788
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v238,878,748 - 8,907,200 (+)NCBI
RefSeq Acc Id: XM_063603719   ⟹   XP_063459789
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v238,885,628 - 8,907,200 (+)NCBI
Ensembl Acc Id: ENSPPAP00000026265   ⟸   ENSPPAT00000049098
Ensembl Acc Id: ENSPPAP00000026273   ⟸   ENSPPAT00000049106
Ensembl Acc Id: ENSPPAP00000026277   ⟸   ENSPPAT00000049110
RefSeq Acc Id: XP_034807806   ⟸   XM_034951915
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BB06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034807808   ⟸   XM_034951917
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BB06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034807807   ⟸   XM_034951916
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BB06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063459788   ⟸   XM_063603718
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BB06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063459789   ⟸   XM_063603719
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BB06 (UniProtKB/TrEMBL)
Protein Domains
FZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036243 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049098.1 UniProtKB/TrEMBL
  ENSPPAT00000049106.1 UniProtKB/TrEMBL
  ENSPPAT00000049110.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.2000.10 UniProtKB/TrEMBL
  Carboxypeptidase-like, regulatory domain UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CarboxyPept-like_regulatory UniProtKB/TrEMBL
  Frizzled_dom UniProtKB/TrEMBL
  Frizzled_dom_sf UniProtKB/TrEMBL
  M14_CPZ_CPD UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
  Peptidase_M14_domain UniProtKB/TrEMBL
NCBI Gene CPZ ENTREZGENE
PANTHER CARBOXYPEPTIDASE Z UniProtKB/TrEMBL
  PROTEASE M14 CARBOXYPEPTIDASE UniProtKB/TrEMBL
Pfam CarboxypepD_reg UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
  PF01392 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_2 UniProtKB/TrEMBL
  PS50038 UniProtKB/TrEMBL
SMART FRI UniProtKB/TrEMBL
  Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP SSF49464 UniProtKB/TrEMBL
  SSF63501 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A2R9B9M2_PANPA UniProtKB/TrEMBL
  A0A2R9BB06 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BH91_PANPA UniProtKB/TrEMBL