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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of protein processing
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Accession:GO:0070613 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: regulation of protein maturation by peptide bond cleavage
 alt_id: GO:0010953



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regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) RGD PMID:10924275 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within ISO (PMID:34380733) RGD PMID:34380733 NCBI chr14:34,754,279...34,800,530
Ensembl chr14:34,754,289...34,800,814
JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO (PMID:15930098) RGD PMID:15930098 NCBI chr 3:172,091,591...172,116,497
Ensembl chr 3:151,672,493...151,696,980
JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:1859153|MGI:3027342 (PMID:15930098), (PMID:16254602) RGD PMID:15930098 PMID:16254602 NCBI chr15:35,685,678...35,786,875
Ensembl chr15:31,573,376...31,672,147
JBrowse link
G Inpp5b inositol polyphosphate-5-phosphatase B acts_upstream_of_or_within ISO MGI:2159609 (PMID:11784089) RGD PMID:11784089 NCBI chr 5:136,996,766...137,061,315
Ensembl chr 5:136,996,686...137,061,315
JBrowse link
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 acts_upstream_of_or_within ISO (PMID:21795536) RGD PMID:21795536 NCBI chr 3:108,694,528...108,936,330
Ensembl chr 3:88,239,622...88,481,267
JBrowse link
G Notch4 notch receptor 4 acts_upstream_of_or_within ISO (PMID:24667410) RGD PMID:24667410 NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97760 (PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97592 (PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107 NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prss37 serine protease 37 involved_in ISO (PMID:27649891) RGD PMID:27649891 NCBI chr 4:69,322,977...69,334,555
Ensembl chr 4:69,322,977...69,334,555
JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO MGI:3799278 (PMID:19887680) RGD PMID:19887680 NCBI chr 7:20,740,760...20,903,355
Ensembl chr 7:18,853,322...19,014,967
JBrowse link
G Rnf139 ring finger protein 139 involved_in ISO (PMID:19706601) RGD PMID:19706601 NCBI chr 7:92,329,201...92,340,386
Ensembl chr 7:90,436,621...90,488,009
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:16585392) RGD PMID:16585392 NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:52,631,736...52,906,739
JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in IEA
ISO
GO_REF:0000107
(PMID:18725990)
Ensembl
RGD
PMID:18725990 GO_REF:0000107 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Kng2 kininogen 2 IDA RGD PMID:6685967 RGD:11062094 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 IMP RGD PMID:23369837 RGD:7243115 NCBI chr15:56,967,128...57,015,964
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Ctsz cathepsin Z involved_in IEA
ISO
GO_REF:0000107
(PMID:19433310)
Ensembl
RGD
PMID:19433310 GO_REF:0000107 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645
JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
ISO
IBA
GO_REF:0000107
(PMID:19855083)
GO_REF:0000033
(PMID:18835034), (PMID:19855083), (PMID:8508955)
Ensembl
RGD
GO_Central
PMID:8508955 PMID:18835034 PMID:19855083 GO_REF:0000033 GO_REF:0000107 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IBA
IEA
(PMID:19855083)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:19855083 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:134998) RGD PMID:134998 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871
Ensembl chr 1:94,735,514...94,744,623
JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (PMID:17344476) RGD PMID:17344476 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:22445366)
UniProt
RGD
PMID:22445366 GO_REF:0000024 NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:152,284,857...152,322,686
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:21357679) RGD PMID:21357679 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764|MGI:97513 (PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 NCBI chr19:56,034,248...56,133,538
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IMP Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Snx12 sorting nexin 12 involved_in ISO (PMID:22709416) RGD PMID:22709416 NCBI chr  X:66,226,995...66,356,945
Ensembl chr  X:66,227,053...66,356,950
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:30249802)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:30249802 GO_REF:0000024 GO_REF:0000107 NCBI chr10:66,293,895...66,304,806
Ensembl chr10:65,796,145...65,807,079
JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:168,563,281...168,567,056
Ensembl chr 1:159,151,432...159,155,192
JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:46,785,852...46,800,179
Ensembl chr12:41,131,262...41,139,439
JBrowse link
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:9836589) RGD PMID:9836589 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Clec3b C-type lectin domain family 3, member B involved_in ISS
ISO
GO_REF:0000024
(PMID:12694198)
UniProt
RGD
PMID:12694198 GO_REF:0000024 NCBI chr 8:131,687,575...131,693,292
Ensembl chr 8:122,810,149...122,815,835
JBrowse link
G Eno1 enolase 1 involved_in ISO (PMID:12666133) RGD PMID:12666133 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336
JBrowse link
G F12 coagulation factor XII involved_in IEA
ISO
GO_REF:0000107
(PMID:89876)
Ensembl
RGD
PMID:89876 GO_REF:0000107 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Hpn hepsin involved_in ISO
IEA
ISS
(PMID:16908524)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16908524 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,464,468...95,480,169
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Meltf melanotransferrin involved_in ISO (PMID:16713448) RGD PMID:16713448 NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300
JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:19897580)
GO_Central
RGD
PMID:19897580 GO_REF:0000033 NCBI chr 1:227,099,005...227,111,277
Ensembl chr 1:227,099,015...227,111,194
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 IDA RGD PMID:11027681 RGD:67924 NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:120,932,417...121,029,384
JBrowse link
G S100a10 S100 calcium binding protein A10 involved_in IEA
ISO
GO_REF:0000107
(PMID:9836589)
Ensembl
RGD
PMID:9836589 GO_REF:0000107 NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:179,220,887...179,229,661
JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl8 angiopoietin-like 8 acts_upstream_of_or_within ISO (PMID:23150577) RGD PMID:23150577 NCBI chr 8:28,652,555...28,654,581
Ensembl chr 8:20,376,462...20,378,490
JBrowse link
G Astl astacin like metalloendopeptidase involved_in ISO (PMID:22472438) RGD PMID:22472438 NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868
JBrowse link
G Bag2 BAG cochaperone 2 involved_in ISO (PMID:16207813) RGD PMID:16207813 NCBI chr 9:43,465,993...43,476,637
Ensembl chr 9:35,970,033...35,980,721
JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 involved_in ISO (PMID:24552833) RGD PMID:24552833 NCBI chr18:61,849,821...62,093,876
Ensembl chr18:59,580,768...59,824,400
JBrowse link
G Cntn2 contactin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18278038)
GO_REF:0000107
RGD
Ensembl
PMID:18278038 GO_REF:0000107 NCBI chr13:46,497,269...46,528,112
Ensembl chr13:43,947,265...43,975,887
JBrowse link
G Ctnnd1 catenin delta 1 acts_upstream_of_or_within ISO MGI:98397 (PMID:17344476) RGD PMID:17344476 NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Fuz fuzzy planar cell polarity protein acts_upstream_of_or_within ISO MGI:4346364 (PMID:19877275) RGD PMID:19877275 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
G Mbl2 mannose binding lectin 2 IDA Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Mmp14 matrix metallopeptidase 14 IMP RGD PMID:14668206 RGD:1582606 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:15064403) RGD PMID:15064403 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992) RGD PMID:15882992 NCBI chr 6:26,743,658...26,771,783
Ensembl chr 6:20,995,266...21,018,248
JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:22795130)
UniProt
RGD
PMID:22795130 GO_REF:0000024 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689
JBrowse link
G Spon1 spondin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16227578)
Ensembl
RGD
PMID:16227578 GO_REF:0000107 NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:167,928,972...168,228,226
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:105100 (PMID:17344476) RGD PMID:17344476 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A IMP RGD PMID:9756630 RGD:13463485 NCBI chr13:49,282,918...49,296,363
Ensembl chr13:46,730,660...46,742,655
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 IMP RGD PMID:9756630 RGD:13463485 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
Ensembl chr 3:7,409,688...7,436,379
Ensembl chr 6:7,409,688...7,436,379
JBrowse link
G Tnp1 transition protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:28366643)
UniProt
RGD
PMID:28366643 GO_REF:0000024 NCBI chr 9:82,043,669...82,044,278
Ensembl chr 9:74,594,466...74,595,274
JBrowse link
G Tnp2 transition protein 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28366643)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28366643 GO_REF:0000024 GO_REF:0000107 NCBI chr10:5,386,735...5,387,463
Ensembl chr10:4,879,812...4,880,538
JBrowse link
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in IEA
ISO
GO_REF:0000107
(PMID:23325791)
Ensembl
RGD
PMID:23325791 GO_REF:0000107 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO
IEA
(PMID:23325791)
GO_REF:0000107
RGD
Ensembl
PMID:23325791 GO_REF:0000107 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO (PMID:11799113), (PMID:9130696) RGD PMID:9130696 PMID:11799113 NCBI chr 1:143,757,389...143,770,430
Ensembl chr 1:134,348,144...134,364,314
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      metabolic process 12160
        macromolecule metabolic process 9981
          protein metabolic process 5234
            proteolysis 1701
              protein processing 259
                regulation of protein processing 64
                  negative regulation of protein processing + 21
                  positive regulation of protein processing + 30
                  regulation of peptide hormone processing + 0
                  regulation of plasminogen activation + 15
                  regulation of protein processing in phagocytic vesicle + 2
                  regulation of protein processing involved in protein targeting to mitochondrion + 1
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        regulation of cellular process 13014
          regulation of metabolic process 6834
            regulation of biosynthetic process 5630
              regulation of macromolecule biosynthetic process 5425
                regulation of gene expression 5308
                  regulation of protein maturation 67
                    regulation of protein processing 64
                      negative regulation of protein processing + 21
                      positive regulation of protein processing + 30
                      regulation of peptide hormone processing + 0
                      regulation of plasminogen activation + 15
                      regulation of protein processing in phagocytic vesicle + 2
                      regulation of protein processing involved in protein targeting to mitochondrion + 1
paths to the root