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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of protein processing
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Accession:GO:0070613 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: regulation of protein maturation by peptide bond cleavage
 alt_id: GO:0010953



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regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) RGD PMID:10924275 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO (MGI:3579954|PMID:15930098) RGD PMID:15930098 MGI:3579954 NCBI chr 3:151,672,505...151,696,975
Ensembl chr 3:151,672,493...151,696,980
JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:1859153|MGI:3027342 (MGI:3579954|PMID:15930098), (MGI:3692156|PMID:16254602) RGD PMID:15930098 PMID:16254602 MGI:3579954 MGI:3692156 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147
JBrowse link
G Inpp5b inositol polyphosphate-5-phosphatase B acts_upstream_of_or_within ISO MGI:2159609 (MGI:2156268|PMID:11784089) RGD PMID:11784089 MGI:2156268 NCBI chr 5:136,996,766...137,061,315
Ensembl chr 5:136,996,686...137,061,315
JBrowse link
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 acts_upstream_of_or_within ISO (MGI:5139915|PMID:21795536) RGD PMID:21795536 MGI:5139915 NCBI chr 3:88,239,529...88,481,291
Ensembl chr 3:88,239,622...88,481,267
JBrowse link
G Notch4 notch receptor 4 acts_upstream_of_or_within ISO (MGI:5581550|PMID:24667410) RGD PMID:24667410 MGI:5581550 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97760 (MGI:5308523|PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107 MGI:5308523 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta acts_upstream_of_or_within ISO MGI:97592 (MGI:5308523|PMID:22007132) RGD PMID:22007132 MGI:5308523 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prss37 serine protease 37 involved_in ISO (PMID:27649891) RGD PMID:27649891 NCBI chr 4:69,322,977...69,334,555
Ensembl chr 4:69,322,977...69,334,555
JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO MGI:3799278 (MGI:5430880|PMID:19887680) RGD PMID:19887680 MGI:5430880 NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967
JBrowse link
G Rnf139 ring finger protein 139 involved_in ISO (PMID:19706601) RGD PMID:19706601 NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (MGI:3710915|PMID:16585392) RGD PMID:16585392 MGI:3710915 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739
JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in ISO
IEA
(PMID:18725990)
GO_REF:0000107
RGD
Ensembl
PMID:18725990 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Kng2 kininogen 2 IDA RGD PMID:6685967 RGD:11062094 NCBI chr11:77,913,876...77,936,247 JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin involved_in ISO
IBA
(PMID:2407243)
PMID:21873635
RGD PMID:2407243 PMID:21873635 RGD:13792537 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cst7 cystatin F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5910746 (MGI:5904382|PMID:28251676)
RGD PMID:28251676 PMID:21873635 MGI:5904382, RGD:13792537 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:11821383) RGD PMID:11821383 NCBI chr10:55,838,381...55,904,374 JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IMP
PMID:17292893
PMID:16639714
UniProt PMID:17292893 PMID:16639714 RGD:10047212, RGD:10047164 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l12 BCL2 like 12 involved_in ISO (PMID:22262180) RGD PMID:22262180 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
JBrowse link
G Fcmr Fc fragment of IgM receptor acts_upstream_of_or_within ISO (MGI:3576402|PMID:15632112) RGD PMID:15632112 MGI:3576402 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
(PMID:15509781)
GO_REF:0000107
RGD
Ensembl
PMID:15509781 GO_REF:0000107 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2681362|PMID:14623868)
Ensembl
RGD
PMID:14623868 GO_REF:0000107 MGI:2681362 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 IMP RGD PMID:23369837 RGD:7243115 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Ctsz cathepsin Z involved_in ISO (PMID:19433310) RGD PMID:19433310 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645
JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:4418017|PMID:19855083)
(PMID:18835034), (PMID:19855083), (PMID:8508955)
Ensembl
RGD
PMID:8508955 PMID:18835034 PMID:19855083 PMID:21873635 GO_REF:0000107 MGI:4418017, RGD:13792537 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IBA
IEA
(PMID:19855083)
PMID:21873635
GO_REF:0000107
(MGI:4418017|PMID:19855083)
RGD
Ensembl
PMID:19855083 PMID:21873635 GO_REF:0000107 MGI:4418017, RGD:13792537 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:134998) RGD PMID:134998 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871
Ensembl chr 1:94,735,514...94,744,623
JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (MGI:3763814|PMID:17344476) RGD PMID:17344476 MGI:3763814 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO
ISS
(PMID:22445366)
GO_REF:0000024
RGD
UniProt
PMID:22445366 GO_REF:0000024 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Fmr1 FMRP translational regulator 1 IMP Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:21357679) RGD PMID:21357679 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764|MGI:97513 (MGI:4829577|PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5468848|PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107 MGI:5468848 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IMP Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Snx12 sorting nexin 12 involved_in ISO (PMID:22709416) RGD PMID:22709416 NCBI chr  X:66,226,995...66,356,945
Ensembl chr  X:66,227,053...66,356,950
JBrowse link
G Tmem59 transmembrane protein 59 involved_in ISO (PMID:20427278) RGD PMID:20427278 NCBI chr 5:121,962,507...121,983,625
Ensembl chr 5:121,962,440...121,983,625
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
GO_REF:0000024
(MGI:6258499|PMID:30249802)
UniProt
RGD
PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
JBrowse link
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec3b C-type lectin domain family 3, member B involved_in ISS
ISO
GO_REF:0000024
(MGI:5447625|PMID:12694198)
UniProt
RGD
PMID:12694198 GO_REF:0000024 MGI:5447625 NCBI chr 8:122,810,091...122,817,039
Ensembl chr 8:122,810,149...122,815,835
JBrowse link
G Eno1 enolase 1 involved_in ISO (PMID:12666133) RGD PMID:12666133 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA
(PMID:89876)
GO_REF:0000107
RGD
Ensembl
PMID:89876 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Hpn hepsin involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16908524)
UniProt
Ensembl
RGD
PMID:16908524 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Meltf melanotransferrin involved_in ISO (PMID:16713448) RGD PMID:16713448 NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300
JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4437195|PMID:19897580)
RGD PMID:19897580 PMID:21873635 MGI:4437195, RGD:13792537 NCBI chr 1:227,099,005...227,111,277
Ensembl chr 1:227,099,015...227,111,194
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 IDA RGD PMID:11027681 RGD:67924 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384
JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl8 angiopoietin-like 8 acts_upstream_of_or_within ISO (PMID:23150577) RGD PMID:23150577 NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
JBrowse link
G Astl astacin like metalloendopeptidase involved_in ISO (MGI:5427546|PMID:22472438) RGD PMID:22472438 MGI:5427546 NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868
JBrowse link
G Bag2 BAG cochaperone 2 involved_in ISO (PMID:16207813) RGD PMID:16207813 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721
JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 involved_in ISO
IEA
(PMID:24552833)
GO_REF:0000107
RGD
Ensembl
PMID:24552833 GO_REF:0000107 NCBI chr18:59,579,851...59,823,977 JBrowse link
G Cntn2 contactin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3835738|PMID:18278038)
Ensembl
RGD
PMID:18278038 GO_REF:0000107 MGI:3835738 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887
JBrowse link
G Ctnnd1 catenin delta 1 acts_upstream_of_or_within ISO MGI:98397 (MGI:3763814|PMID:17344476) RGD PMID:17344476 MGI:3763814 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Fuz fuzzy planar cell polarity protein acts_upstream_of_or_within ISO MGI:4346364 (MGI:4367921|PMID:19877275) RGD PMID:19877275 MGI:4367921 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
G Mbl2 mannose binding lectin 2 IDA Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mmp14 matrix metallopeptidase 14 IMP RGD PMID:14668206 RGD:1582606 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 involved_in ISO (PMID:15064403) RGD PMID:15064403 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992) RGD PMID:15882992 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5437551|PMID:22795130)
UniProt
RGD
PMID:22795130 GO_REF:0000024 MGI:5437551 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689
JBrowse link
G Spon1 spondin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3607023|PMID:16227578)
Ensembl
RGD
PMID:16227578 GO_REF:0000107 MGI:3607023 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:105100 (MGI:3763814|PMID:17344476) RGD PMID:17344476 MGI:3763814 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A IMP RGD PMID:9756630 RGD:13463485 NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 IMP RGD PMID:9756630 RGD:13463485 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
JBrowse link
G Tnp1 transition protein 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5897488|PMID:28366643)
UniProt
RGD
PMID:28366643 GO_REF:0000024 MGI:5897488 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274
JBrowse link
G Tnp2 transition protein 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5897488|PMID:28366643)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28366643 GO_REF:0000024 GO_REF:0000107 MGI:5897488 NCBI chr10:4,879,812...4,880,540
Ensembl chr10:4,879,812...4,880,538
JBrowse link
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO (MGI:5619440|PMID:23325791) RGD PMID:23325791 MGI:5619440 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO (MGI:5619440|PMID:23325791) RGD PMID:23325791 MGI:5619440 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
positive regulation of sterol regulatory element binding protein cleavage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5927299|PMID:28846071)
UniProt
RGD
PMID:28846071 GO_REF:0000024 MGI:5927299 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO (PMID:11799113), (PMID:9130696) RGD PMID:9130696 PMID:11799113 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      nitrogen compound metabolic process 9922
        regulation of nitrogen compound metabolic process 5516
          regulation of protein metabolic process 2642
            regulation of proteolysis 806
              regulation of protein processing 70
                negative regulation of protein processing + 29
                positive regulation of protein processing + 29
                regulation of peptide hormone processing + 0
                regulation of plasminogen activation + 13
                regulation of protein processing in phagocytic vesicle + 2
                regulation of protein processing involved in protein targeting to mitochondrion + 1
                regulation of sterol regulatory element binding protein cleavage + 1
Path 2
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      organic substance metabolic process 11278
        macromolecule metabolic process 9736
          protein metabolic process 5848
            proteolysis 1872
              protein processing 243
                regulation of protein processing 70
                  negative regulation of protein processing + 29
                  positive regulation of protein processing + 29
                  regulation of peptide hormone processing + 0
                  regulation of plasminogen activation + 13
                  regulation of protein processing in phagocytic vesicle + 2
                  regulation of protein processing involved in protein targeting to mitochondrion + 1
                  regulation of sterol regulatory element binding protein cleavage + 1
paths to the root