MYH9 (myosin heavy chain 9) - Rat Genome Database
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Gene: MYH9 (myosin heavy chain 9) Pan paniscus
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Symbol: MYH9
Name: myosin heavy chain 9
RGD ID: 11705125
Description: ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); actin-dependent ATPase activity (ortholog); INVOLVED IN actin cytoskeleton reorganization (ortholog); actin filament bundle assembly (ortholog); actin filament bundle distribution (ortholog); PARTICIPATES IN follicle-stimulating hormone signaling pathway; ASSOCIATED WITH AIDS-Associated Nephropathy (ortholog); Albuminuria (ortholog); Alport syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); actin filament (ortholog); actomyosin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: myosin-9
Orthologs:
Homo sapiens (human) : MYH9 (myosin heavy chain 9)  HGNC  Alliance
Mus musculus (house mouse) : Myh9 (myosin, heavy polypeptide 9, non-muscle)  MGI  Alliance
Rattus norvegicus (Norway rat) : Myh9 (myosin, heavy chain 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh9 (myosin heavy chain 9)
Canis lupus familiaris (dog) : MYH9 (myosin heavy chain 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh9 (myosin heavy chain 9)
Sus scrofa (pig) : MYH9 (myosin heavy chain 9)
Chlorocebus sabaeus (African green monkey) : MYH9 (myosin heavy chain 9)
Heterocephalus glaber (naked mole-rat) : Myh9 (myosin heavy chain 9)
more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12235,039,461 - 35,121,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,039,101 - 35,121,618 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02217,200,623 - 17,305,826 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton reorganization  (ISO)
actin filament bundle assembly  (ISO)
actin filament bundle distribution  (ISO)
actin filament capping  (ISO)
actin filament polymerization  (ISO)
actin filament-based movement  (ISO)
actomyosin structure organization  (ISO)
angiogenesis  (ISO)
blood vessel endothelial cell migration  (ISO)
cell adhesion  (ISO)
cell morphogenesis involved in differentiation  (ISO)
cell-cell adhesion  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cytokinetic process  (ISO)
establishment of meiotic spindle localization  (ISO)
establishment of T cell polarity  (ISO)
follicle-stimulating hormone signaling pathway  (ISO)
in utero embryonic development  (ISO)
lysosome localization  (ISO)
meiotic spindle organization  (ISO)
membrane protein ectodomain proteolysis  (ISO)
monocyte differentiation  (ISO)
myoblast fusion  (ISO)
negative regulation of actin filament severing  (ISO)
negative regulation of vascular associated smooth muscle cell migration  (ISO)
phagocytosis, engulfment  (ISO)
plasma membrane repair  (ISO)
platelet aggregation  (ISO)
platelet formation  (ISO)
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  (ISO)
positive regulation of endocytosis  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of focal adhesion assembly  (ISO)
positive regulation of G protein-coupled receptor signaling pathway  (ISO)
positive regulation of inositol trisphosphate biosynthetic process  (ISO)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
positive regulation of phagocytosis  (ISO)
positive regulation of protein processing in phagocytic vesicle  (ISO)
protein transport  (ISO)
regulated exocytosis  (ISO)
regulation of cell shape  (ISO)
regulation of plasma membrane repair  (ISO)
uropod organization  (ISO)
vesicle targeting  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
MYH9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12235,039,461 - 35,121,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,039,101 - 35,121,618 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02217,200,623 - 17,305,826 (-)NCBIMhudiblu_PPA_v0panPan3
MYH9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2236,281,280 - 36,387,967 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl2236,281,277 - 36,388,067 (-)EnsemblGRCh38hg38GRCh38
GRCh382236,281,280 - 36,387,967 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372236,677,323 - 36,784,107 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,007,272 - 35,113,927 (-)NCBINCBI36hg18NCBI36
Build 342235,001,826 - 35,108,481NCBI
Celera2220,479,895 - 20,586,681 (-)NCBI
Cytogenetic Map22q12.3NCBI
HuRef2219,645,404 - 19,752,216 (-)NCBIHuRef
CHM1_12236,636,447 - 36,743,245 (-)NCBICHM1_1
Myh9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391577,644,785 - 77,726,375 (-)NCBI
GRCm381577,760,585 - 77,842,175 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1577,760,587 - 77,842,175 (-)EnsemblGRCm38mm10GRCm38
MGSCv371577,591,019 - 77,672,545 (-)NCBIGRCm37mm9NCBIm37
MGSCv361577,587,843 - 77,669,360 (-)NCBImm8
Celera1579,227,040 - 79,308,545 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1536.81NCBI
Myh9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07118,740,005 - 118,792,507 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,741,110 - 118,792,625 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07118,737,555 - 118,797,086 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47115,681,459 - 115,732,774 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17115,715,686 - 115,767,004 (-)NCBI
Celera7105,684,430 - 105,736,878 (-)NCBICelera
Cytogenetic Map7q34NCBI
RH 3.4 Map7811.2RGD
Myh9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541322,881,045 - 22,972,450 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541322,881,759 - 22,972,182 (-)NCBIChiLan1.0ChiLan1.0
MYH9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1028,063,624 - 28,122,953 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11028,063,626 - 28,122,953 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Myh9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364924,384,215 - 4,466,229 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYH9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1511,365,603 - 11,456,475 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.259,076,302 - 9,165,918 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYH9
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1918,986,598 - 19,052,671 (-)Ensembl
ChlSab1.11918,985,709 - 19,093,304 (-)NCBI
Myh9
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475211,327,881 - 11,414,037 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000047491   ⟹   ENSPPAP00000024666
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2235,039,101 - 35,121,618 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000047498   ⟹   ENSPPAP00000024673
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2235,040,489 - 35,105,800 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000047504   ⟹   ENSPPAP00000024679
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2235,040,489 - 35,105,800 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000047513   ⟹   ENSPPAP00000024688
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2235,040,489 - 35,105,800 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000047516   ⟹   ENSPPAP00000024691
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2235,081,494 - 35,105,800 (-)Ensembl
RefSeq Acc Id: XM_034948846   ⟹   XP_034804737
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02217,200,623 - 17,305,826 (-)NCBI
RefSeq Acc Id: XM_034948847   ⟹   XP_034804738
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02217,200,623 - 17,305,826 (-)NCBI
RefSeq Acc Id: XM_034948848   ⟹   XP_034804739
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02217,200,623 - 17,305,778 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034804737 (Get FASTA)   NCBI Sequence Viewer  
  XP_034804738 (Get FASTA)   NCBI Sequence Viewer  
  XP_034804739 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_034804738   ⟸   XM_034948847
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034804737   ⟸   XM_034948846
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034804739   ⟸   XM_034948848
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000024666   ⟸   ENSPPAT00000047491
RefSeq Acc Id: ENSPPAP00000024673   ⟸   ENSPPAT00000047498
RefSeq Acc Id: ENSPPAP00000024691   ⟸   ENSPPAT00000047516
RefSeq Acc Id: ENSPPAP00000024688   ⟸   ENSPPAT00000047513
RefSeq Acc Id: ENSPPAP00000024679   ⟸   ENSPPAT00000047504

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035338 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000024666 UniProtKB/TrEMBL
  ENSPPAP00000024673 UniProtKB/TrEMBL
  ENSPPAP00000024679 UniProtKB/TrEMBL
  ENSPPAP00000024688 UniProtKB/TrEMBL
  ENSPPAP00000024691 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047491 UniProtKB/TrEMBL
  ENSPPAT00000047498 UniProtKB/TrEMBL
  ENSPPAT00000047504 UniProtKB/TrEMBL
  ENSPPAT00000047513 UniProtKB/TrEMBL
  ENSPPAT00000047516 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.360 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  4.10.270.10 UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_IQ_contain_sf UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/TrEMBL
  Myosin_tail UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
KEGG Report pps:100984241 UniProtKB/TrEMBL
NCBI Gene MYH9 ENTREZGENE
Pfam Myosin_head UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/TrEMBL
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/TrEMBL
SMART MYSc UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9B513_PANPA UniProtKB/TrEMBL
  A0A2R9B529_PANPA UniProtKB/TrEMBL
  A0A2R9B6H2_PANPA UniProtKB/TrEMBL
  A0A2R9B6K2_PANPA UniProtKB/TrEMBL
  A0A2R9BBZ8_PANPA UniProtKB/TrEMBL