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Gene: CYFIP2 (cytoplasmic FMR1 interacting protein 2) Pan paniscus

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Symbol:

CYFIP2

Name:

cytoplasmic FMR1 interacting protein 2

RGD ID:

11968063

Description:

ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN apoptotic process (inferred); cell-cell adhesion (inferred); dendrite extension (inferred); PARTICIPATES IN E-cadherin signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 65 (ortholog); Developmental Disabilities (ortholog); epilepsy (ortholog); FOUND IN synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cytoplasmic FMR1-interacting protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	152,461,545 - 152,591,293 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	150,601,092 - 150,730,844 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	152,667,136 - 152,796,575 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	159,288,779 - 159,418,077 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	159,292,029 - 159,418,077 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 65 (ISO)

Developmental Disabilities (ISO)

epilepsy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

lymphoproliferative syndrome 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA)

cell-cell adhesion (IEA)

dendrite extension (IEA)

neuron projection development (IEA)

positive regulation of neurotrophin TRK receptor signaling pathway (IEA)

positive regulation of proteolysis (IEA)

regulation of actin filament polymerization (IEA)

regulation of postsynapse assembly (IEA)

Cellular Component

cytoplasm (IEA)

neuron projection (IEA)

perinuclear region of cytoplasm (IEA)

SCAR complex (IEA)

synapse (IEA,ISO)

Molecular Function

protein binding (ISO)

small GTPase binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

E-cadherin signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CYFIP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	152,461,545 - 152,591,293 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	150,601,092 - 150,730,844 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	152,667,136 - 152,796,575 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	159,288,779 - 159,418,077 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	159,292,029 - 159,418,077 (+)	Ensembl	panpan1.1		panPan2

CYFIP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	157,266,123 - 157,395,594 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	157,266,079 - 157,395,595 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	156,693,133 - 156,822,602 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	156,625,669 - 156,755,184 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	156,628,929 - 156,752,793	NCBI
Celera	5	152,719,640 - 152,849,168 (+)	NCBI		Celera
Cytogenetic Map	5	q33.3	NCBI
HuRef	5	151,780,753 - 151,910,647 (+)	NCBI		HuRef
CHM1_1	5	156,125,748 - 156,255,279 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	157,785,054 - 157,914,553 (+)	NCBI		T2T-CHM13v2.0

Cyfip2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	46,084,676 - 46,203,686 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	46,084,677 - 46,203,686 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	46,193,849 - 46,312,859 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	46,193,850 - 46,312,859 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	46,007,360 - 46,125,852 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	46,037,281 - 46,155,773 (-)	NCBI		MGSCv36	mm8
Celera	11	50,779,500 - 50,898,263 (-)	NCBI		Celera
Cytogenetic Map	11	B1.1	NCBI
cM Map	11	27.61	NCBI

Cyfip2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	31,122,653 - 31,242,440 (-)	NCBI		GRCr8
mRatBN7.2	10	30,621,318 - 30,741,113 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	30,621,318 - 30,741,113 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	35,348,673 - 35,468,277 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	3,887,117 - 4,006,729 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	30,323,472 - 30,442,925 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	31,278,746 - 31,419,235 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	31,278,746 - 31,419,235 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	31,097,979 - 31,198,028 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	31,321,000 - 31,443,480 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	31,324,310 - 31,444,535 (-)	NCBI
Celera	10	30,074,331 - 30,193,168 (-)	NCBI		Celera
Cytogenetic Map	10	q21	NCBI

Cyfip2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	11,462,837 - 11,588,378 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	11,483,891 - 11,586,628 (+)	NCBI	ChiLan1.0	ChiLan1.0

CYFIP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	52,769,638 - 52,875,080 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	52,743,048 - 52,880,589 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	52,661,797 - 52,785,745 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	53,206,203 - 53,330,066 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	4	53,032,652 - 53,138,139 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	53,139,468 - 53,263,349 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	53,656,324 - 53,780,306 (-)	NCBI		UU_Cfam_GSD_1.0

Cyfip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	107,310,615 - 107,431,342 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936515	5,759,345 - 5,880,713 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936515	5,759,940 - 5,880,688 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYFIP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	65,852,588 - 66,001,559 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	65,852,584 - 66,001,576 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	71,707,184 - 71,865,915 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CYFIP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	59,661,045 - 59,794,717 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	59,661,089 - 59,794,826 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	17,835,766 - 17,969,652 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cyfip2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	31,996,423 - 32,115,577 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	31,996,717 - 32,115,571 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003818984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003818985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034960877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034960878	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034960879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000061873 ⟹ ENSPPAP00000038964

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	159,292,029 - 159,418,077 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000061901 ⟹ ENSPPAP00000038992

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	159,308,026 - 159,415,485 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000061908 ⟹ ENSPPAP00000038999

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	159,308,026 - 159,415,485 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000061911 ⟹ ENSPPAP00000039002

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	159,308,026 - 159,415,485 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000061913 ⟹ ENSPPAP00000039004

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	159,308,026 - 159,415,485 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000061916 ⟹ ENSPPAP00000039007

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	159,308,026 - 159,415,485 (+)	Ensembl

RefSeq Acc Id:

XM_003818984 ⟹ XP_003819032

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	4	152,461,545 - 152,591,293 (+)	NCBI
NHGRI_mPanPan1	5	150,601,092 - 150,730,844 (+)	NCBI
Mhudiblu_PPA_v0	5	152,667,172 - 152,796,575 (+)	NCBI
PanPan1.1	5	159,288,779 - 159,418,077 (+)	NCBI

Sequence:

show sequence

GCGGGGCCGGGCCGGGGCCGAGCGCGGCGCAGCGGAGCGGGGCAGAGCATCCTGCGCCCGGCGC
GGGCCCTGCGGTAGCCTCGGGCCCCCTCCCCTGGACCCCACCGCAGAGCCAGTGCAGAATACAG
AAACTGCAGCCATGACCACGCACGTCACCCTGGAAGATGCCCTGTCCAACGTGGACCTGCTTGA
AGAGCTTCCCCTCCCCGACCAGCAGCCATGCATCGAGCCTCCACCTTCCTCCATCATGTACCAG
GCTAACTTTGACACAAACTTTGAGGACAGGAATGCATTTGTCACGGGCATTGCAAGGTACATTG
AGCAGGCTACAGTCCACTCCAGCATGAATGAGATGCTGGAGGAAGGACATGAGTATGCGGTCAT
GCTGTACACCTGGCGCAGCTGTTCCCGGGCCATTCCCCAGGTGAAATGCAATGAGCAGCCCAAC
CGAGTAGAGATCTATGAGAAGACAGTGGAGGTGCTGGAGCCGGAGGTCACCAAGCTCATGAAGT
TCATGTATTTTCAGCGCAAGGCCATCGAGCGGTTCTGCAGCGAGGTGAAGCGGCTGTGCCATGC
CGAGCGCAGGAAGGACTTTGTCTCTGAGGCCTACCTCCTGACCCTGGGCAAGTTCATCAACATG
TTTGCTGTCCTGGATGAGCTAAAGAACATGAAGTGCAGCGTCAAGAATGACCACTCTGCCTACA
AGAGGGCAGCACAGTTCCTGCGGAAGATGGCAGATCCCCAGTCTATCCAGGAGTCGCAGAACCT
TTCCATGTTCCTGGCCAACCACAACAGGATCACCCAGTGTCTCCACCAGCAACTTGAAGTGATC
CCAGGCTATGAGGAGCTGCTGGCTGACATTGTCAACATCTGCGTGGATTACTACGAGAACAAGA
TGTACCTGACCCCCAGTGAGAAACATATGCTCCTCAAGGTGATGGGCTTTGGCCTCTACCTAAT
GGATGGAAATGTCAGTAACATTTACAAACTGGATGCCAAGAAGAGAATTAATCTTAGCAAAATT
GATAAATTCTTTAAGCAGCTGCAGGTGGTGCCCCTTTTCGGCGACATGCAGATAGAGCTGGCCA
GATACATTAAGACCAGTGCTCACTATGAAGAGAACAAGTCCAAGTGGACGTGCACCCAGAGCAG
CATCAGCCCCCAGTACAATATCTGCGAGCAGATGGTTCAGATCCGGGATGACCACATCCGCTTC
ATCTCCGAGCTCGCTCGCTACAGCAACAGTGAGGTGGTGACGGGCTCAGGGCTGGACAGCCAGA
AGTCAGACGAGGAGTATCGCGAGCTCTTCGACTTAGCCCTGCGGGGTCTGCAGCTTCTATCCAA
GTGGAGCGCCCACGTCATGGAGGTGTACTCTTGGAAGCTGGTTCATCCCACAGACAAGTTCTGC
AACAAGGACTGTCCTGGCACCGCGGAGGAATATGAGAGAGCCACACGCTACAATTACACCAGTG
AGGAAAAATTTGCCTTCGTTGAGGTGATCGCCATGATCAAAGGCCTGCAGGTGCTCATGGGCAG
GATGGAGAGCGTCTTCAACCAGGCCATCAGGAACACCATCTACGCGGCATTGCAGGACTTCGCC
CAGGTGACGCTGCGTGAGCCCCTGCGGCAGGCAGTACGAAAGAAGAAGAATGTCCTCATCAGTG
TCCTACAGGCAATTCGAAAGACCATCTGTGACTGGGAGGGAGGGCGAGAGCCCCCTAATGACCC
ATGCTTGAGAGGGGAGAAGGACCCCAAAGGTGGATTTGATATCAAGGTGCCCCGGCGTGCTGTG
GGGCCATCCAGCACACAGCTGTACATGGTGCGGACCATGCTTGAATCACTCATTGCAGACAAAA
GCGGCTCCAAGAAGACCCTGAGGAGCAGCCTGGATGGACCCATTGTCCTCGCCATAGAGGACTT
TCACAAACAGTCCTTCTTCTTCACACATCTGCTCAACATCAGTGAAGCCCTGCAGCAGTGTTGT
GACCTCTCCCAGCTCTGGTTCCGAGAATTCTTCCTGGAGTTAACCATGGGCCGACGAATCCAGT
TCCCCATCGAGATGTCCATGCCCTGGATTCTAACGGACCATATCCTGGAAACCAAAGAACCTTC
CATGATGGAGTATGTCCTCTACCCTCTGGATCTGTACAACGACAGCGCCTACTATGCTCTGACC
AAGTTTAAAAAGCAGTTCCTGTACGATGAGATAGAAGCGGAGGTGAACCTGTGTTTTGATCAGT
TTGTCTACAAGCTGGCAGACCAGATCTTTGCTTACTACAAAGCCATGGCTGGCAGTGTCCTGTT
GGATAAACGTTTTCGAGCTGAGTGTAAGAATTATGGCGTCATCATTCCGTATCCACCGTCCAAT
CGCTATGAAACACTGCTGAAGCAGAGACACGTCCAGCTGTTGGGTAGATCAATTGACTTGAACA
GACTCATTACCCAGCGCATCTCTGCCGCCATGTATAAATCCCTGGACCAAGCTATCAGCCGCTT
TGAGAGTGAGGACCTGACCTCCATTGTGGAGCTGGAGTGGCTGCTGGAGATTAACCGGCTCACG
CATCGGCTGCTCTGTAAGCATATGACACTGGACAGCTTCGATGCCATGTTCCGAGAGGCCAATC
ATAATGTGTCCGCCCCCTATGGCCGTATCACCCTGCATGTCTTCTGGGAACTGAACTTTGACTT
TCTCCCCAACTACTGCTACAATGGGTCCACTAACCGTTTTGTGCGGACTGCCATTCCTTTCACC
CAAGAACCACAACGAGACAAACCTGCCAACGTCCAGCCTTATTACCTCTATGGATCCAAGCCTC
TCAACATTGCCTACAGCCACATCTACAGCTCCTACAGGAATTTCGTGGGGCCACCTCATTTCAA
GACTATCTGCAGACTCCTGGGTTATCAGGGCATCGCTGTGGTCATGGAGGAACTGCTAAAGATT
GTGAAGAGCTTGCTCCAAGGAACCATTCTCCAGTATGTGAAAACACTGATAGAGGTGATGCCCA
AGATATGCCGCTTGCCCCGACATGAGTATGGCTCCCCAGGGATCCTGGAGTTCTTCCACCACCA
GCTGAAGGACATCATTGAGTACGCAGAGCTCAAAACAGACGTGTTCCAGAGCCTGAGGGAAGTG
GGCAATGCCATCCTCTTCTGCCTCCTCATAGAGCAAGCTCTGTCTCAGGAGGAGGTCTGCGATT
TGCTCCATGCCGCACCCTTCCAAAACATCTTGCCTAGAGTCTACATCAAAGAGGGGGAGCGCCT
GGAGGTCCGGATGAAACGTCTGGAAGCCAAGTATGCCCCGCTCCACCTGGTCCCTCTGATCGAG
CGGCTGGGGACCCCTCAGCAAATCGCCATTGCTCGCGAGGGTGACCTCCTGACCAAGGAGCGGC
TGTGCTGTGGCCTGTCCATGTTCGAGGTCATCCTGACCCGCATTCGGAGCTACCTGCAGGACCC
CATCTGGCGGGGCCCACCGCCCACCAATGGCGTCATGCACGTCGATGAGTGTGTGGAGTTCCAC
CGGCTGTGGAGCGCCATGCAGTTCGTGTACTGCATCCCTGTGGGAACCAACGAGTTCACAGCTG
AGCAGTGTTTCGGCGATGGCTTGAACTGGGCTGGTTGCTCCATCATCGTCCTGCTGGGCCAGCA
GCGTCGCTTCGACCTGTTCGACTTCTGTTACCACCTGCTAAAAGTGCAGAGGCAGGACGGGAAG
GATGAAATCATTAAGAATGTGCCCCTGAAGAAGATGGCCGACCGGATCAGGAAGTATCAGATCT
TGAACAATGAGGTTTTTGCCATCCTGAACAAGTACATGAAGTCCGTGGAGACAGACAGTTCCAC
TGTGGAGCATGTGCGCTGCTTCCAGCCGCCCATCCACCAGTCCTTGGCCACCACTTGCTAAGCA
GAAGATCCTGCAGACCCTTATCTGGAGGAGGAAGAGAAGCAGGAGAGAGAAAGCCACAGCCAGC
CTGCCATAGGATCCAACTGGACAACGTGTGGGATGGACCTGGAAACAAGCACCTCCCCAAACAC
ATCACCACTCCCTAGGGCGGGGCCTGTGCATGCTCTCCCATGACATCTCCATGCTGGTTTCTCC
ATAGCATAAATGAAAAAAAAAAAAAGTAAACAGGGCAGTGTGTGCTTTTTCTTTTCTCCCCCTC
AACTATATTAAGAACTCCTAGTTTCACCCTTTCTCCATCCCATCATCCCACCTATCTGTGGTTG
CTTCCCAAGACCTCCTCCCAAGATAGACATCTCCTACCCAGTGCCCTTGTGTGACCCCAGGACT
CAAGTCTCAGACTGTGAACAGATGTGGCCATGCCCAGAGACGCCAGCCTGGCCAGAAGGGCATG
CCTCAGCTTACTACTTCATCTCTCCTGGTTCCCTCCCTGCAGTGCCCCGGGTGTCATCTTCTCC
CACTCTGGGTACCAGGGATTCTACACCACATAGGCTTCCCAAAGCCCCATTCTAACTCCCCTCT
GTCAGGGACGCCCTAGAGAGAGGTCCAAAAAGCATTCACAGCTGTATCACACTCTATGCAGAGG
TGAGGTAGGAGACTGATCAGGCCTGCTGTGGGGAAGCAGTATGTATGAACACAGCCAGAAATGT
CATAGTCCAAACAGGATGCTTTCAGGCCATCTCAGCTGCTTGATGGTGAGATGGTTCCCTTATT
CCTTCAGGAAAGGCTTAGCATTGGGCCACATAGGGGAAGCAGCTTTGAACAAATCAGTCATAGC
ACTGCCTATAGCATTAGCCAGTGACCAAATTAGGGACAACTTCTTGGCACAGAATTGCTTATCA
AGGAACATTTCCACAAGAAAGAAAATATTAAGGGGTTATTTCCACAGAGGCCCAAAACGTGTTG
GAAACACAGAGGTGAGGAGGAGGAATAGTAATTGTCAATGAGCTTTTAATACCAAGATACACCC
CCTGCCCCCAAAGAAGAGTCCTCTTTTAGGGAATCAGAACCTTCATTGTCCTAGAAGCTGAAAG
ATTCTTGGAACATTTTAGCCTTTACTCTCAACTTGCTGTTCTCTTTACGTTCCTTAAGTTAGAC
TTTCGGGTGTGGCTTCTCTCCCAGGGGTAACATTTACTTCCATTTTCTAGACTGAACCAAAAGT
CTTCTGCAGAATCTCCCACCGAGTGTGGTAAGAAGGAAGGACAAAAGGCTTTAGGATATAAATT
TCATGTTACAGAGCATGTCATTGTCAAAGGAAATCTGTGGCCCTGAGATTTTAAGAACATAAAA
TGTGACATTTGATATTTCTCCAGCCCAGGGAAGTAAGATGGTTAGCAATGGTTGCCTTAAACAA
ATGGTCCCATTTTTAACCCCAAAGGAAGTGCCCACAGCAAGAGGTTTGTGTGATGCACTTATGT
CCTCCGGTGAGGAAAGGGGGCCACATATGAAAGGCCCCTTAGGTCAGATCCTGAGAGTAGCACA
TTTGAGTGCAGATTCCTGGGCCCCACCTCAAACCTACTAATTCTGAATCTCTGGGAATAGGGCC
AGGAAATCTGCCCTTTCTACAAACTACCCAAGTTGTTCTGTTGCACATCAATGTTTGGGAACCA
CTGCTGTAAGGGAATCATTCTGGTCACCTTGAGCTTTGAGCTACCACTAAGCCATGAAAGAAAA
TACATCATACAGGGAAGAGAGAAGGGAGGAGGTTCCAAGTAGTAACTGGCAGATCCTCCTGTCT
GGAGGTACCACCTTCTATTCTGGTTTCTGACTTTTCCTTCTTGATGACCATAGATGTGTTCCAG
AGACAAAAGAGACACATTATCCCAGATGGCAGAACATGCTTTCAAAACATATAAAATGTCAAAG
TTCCAGATCCTTCTACATCTTTAGTCCTGTCTGAGGATGGTAGCTGGCTCTCTGTAGCTGATAG
ATGGCTAGAGTTCCATCCAAATCCTTGACCACGACTTCATGGAGATTTGAATAATCTATTTGAT
GAGATTTCTATTTCAATAACCCACCTCTCTCACCCCACATTCATATCCCTAAATTTGACCCTCT
GGGCCGAGTCACATTACCTTCAGGAGACTTGATCCCAGTAGACTGAGGTCTTCCCTTTCAGCAG
AAAGATTTCATTTCCCTGGCTTGCCAGTGGCACTGATTTCCGAACACCCAATGAGTTTAATATT
CCTTCCTCCTTGGCATTACTGCCCCAGCCTCTTTTTATTTTTTTGTGTGTGTGTCTAATAACCA
GGAAAAAATAAAGCTTAGGTTTTAAAAAGTTTTAAAAATAATCTGTTTCAGAAACTGTCAAATG
TACCATATTTGTATTAAGAGTTGTTGGGAATTTTTGTACACTGAATTTACATTTATTTATGGTG
ACTTATATTTACGCTTGTGATCAAATAATGATGTTAAATTCTTAAATCATATTTGCTATGCAGC
TGAAGATGATATTTTGATTTGTATTTTGGGGGTACCTGTGTTGAGTTGATAAACATTTCCATCT
TCATTAAAACTGCTTCCAAACTAGTAAAA

hide sequence

RefSeq Acc Id:

XM_034960877 ⟹ XP_034816768

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	4	152,461,545 - 152,591,293 (+)	NCBI
NHGRI_mPanPan1	5	150,601,092 - 150,730,844 (+)	NCBI
Mhudiblu_PPA_v0	5	152,667,136 - 152,796,575 (+)	NCBI

RefSeq Acc Id:

XM_034960878 ⟹ XP_034816769

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	4	152,464,923 - 152,591,293 (+)	NCBI
NHGRI_mPanPan1	5	150,604,472 - 150,730,844 (+)	NCBI
Mhudiblu_PPA_v0	5	152,670,511 - 152,794,073 (+)	NCBI

RefSeq Acc Id:

XM_034960879 ⟹ XP_034816770

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	4	152,461,798 - 152,591,293 (+)	NCBI
NHGRI_mPanPan1	5	150,601,352 - 150,730,844 (+)	NCBI
Mhudiblu_PPA_v0	5	152,667,401 - 152,794,073 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003819032	(Get FASTA)	NCBI Sequence Viewer
	XP_034816768	(Get FASTA)	NCBI Sequence Viewer
	XP_034816769	(Get FASTA)	NCBI Sequence Viewer
	XP_034816770	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000038964.1
	ENSPPAP00000038992.1
	ENSPPAP00000038999.1
	ENSPPAP00000039002.1
	ENSPPAP00000039004.1
	ENSPPAP00000039007.1

RefSeq Acc Id:	XP_003819032 ⟸ XM_003818984
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9CAR4 (UniProtKB/TrEMBL), A0A2R9CAU5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQAT VHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYF QRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAA QFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLT PSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIK TSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDE EYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKF AFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQA IRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSK KTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIE MSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYK LADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLIT QRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVS APYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIA YSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICR LPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHA APFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCG LSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCF GDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNE VFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC hide sequence

RefSeq Acc Id:	XP_034816768 ⟸ XM_034960877
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9CLF8 (UniProtKB/TrEMBL), A0A2R9CAU5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034816770 ⟸ XM_034960879
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9CLF8 (UniProtKB/TrEMBL), A0A2R9CAU5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034816769 ⟸ XM_034960878
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9CLF8 (UniProtKB/TrEMBL), A0A2R9CAU5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSPPAP00000038964 ⟸ ENSPPAT00000061873

Ensembl Acc Id:

ENSPPAP00000039007 ⟸ ENSPPAT00000061916

Ensembl Acc Id:

ENSPPAP00000039002 ⟸ ENSPPAT00000061911

Ensembl Acc Id:

ENSPPAP00000039004 ⟸ ENSPPAT00000061913

Ensembl Acc Id:

ENSPPAP00000038992 ⟸ ENSPPAT00000061901

Ensembl Acc Id:

ENSPPAP00000038999 ⟸ ENSPPAT00000061908

Protein Domains

CYRIA/CYRIB Rac1 binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000042023	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000061873.1	UniProtKB/TrEMBL
	ENSPPAT00000061901.1	UniProtKB/TrEMBL
	ENSPPAT00000061908.1	UniProtKB/TrEMBL
	ENSPPAT00000061911.1	UniProtKB/TrEMBL
	ENSPPAT00000061913.1	UniProtKB/TrEMBL
	ENSPPAT00000061916.1	UniProtKB/TrEMBL
InterPro	CYRIA/CYRIB_Rac1-bd	UniProtKB/TrEMBL
	Cytoplasmic_FMR1-int	UniProtKB/TrEMBL
KEGG Report	pps:100982761	UniProtKB/TrEMBL
NCBI Gene	CYFIP2	ENTREZGENE
PANTHER	PTHR12195	UniProtKB/TrEMBL
Pfam	DUF1394	UniProtKB/TrEMBL
	FragX_IP	UniProtKB/TrEMBL
PIRSF	FMR1_interacting	UniProtKB/TrEMBL
PRINTS	CYTOFMRPINTP	UniProtKB/TrEMBL
UniProt	A0A2R9CAR4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CAU5	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CAU7_PANPA	UniProtKB/TrEMBL
	A0A2R9CLF8	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CLG9_PANPA	UniProtKB/TrEMBL
	A0A2R9CLH3_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)