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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein processing
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Accession:GO:0010955 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
Synonyms:exact_synonym: negative regulation of protein maturation by peptide bond cleavage



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negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871
Ensembl chr 1:94,735,514...94,744,623
JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (MGI:3763814|PMID:17344476) RGD PMID:17344476 MGI:3763814 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO
ISS
(PMID:22445366)
GO_REF:0000024
RGD
UniProt
PMID:22445366 GO_REF:0000024 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057 JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:21357679) RGD PMID:21357679 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764|MGI:97513 (MGI:4829577|PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5468848|PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107 MGI:5468848 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IMP Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Snx12 sorting nexin 12 involved_in ISO (PMID:22709416) RGD PMID:22709416 NCBI chr  X:66,226,995...66,356,945
Ensembl chr  X:66,227,053...66,356,950
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6258499|PMID:30249802)
UniProt
Ensembl
RGD
PMID:30249802 GO_REF:0000024 GO_REF:0000107 MGI:6258499 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192
JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 IMP RGD PMID:23369837 RGD:7243115 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Ctsz cathepsin Z involved_in ISO
IEA
(PMID:19433310)
GO_REF:0000107
RGD
Ensembl
PMID:19433310 GO_REF:0000107 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645
JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
(MGI:4418017|PMID:19855083)
(PMID:18835034), (PMID:19855083), (PMID:8508955)
Ensembl
GO_Central
RGD
PMID:8508955 PMID:18835034 PMID:19855083 GO_REF:0000033 GO_REF:0000107 MGI:4418017 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IBA
IEA
(PMID:19855083)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(MGI:4418017|PMID:19855083)
RGD
GO_Central
TreeGrafter
Ensembl
PMID:19855083 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:134998) RGD PMID:134998 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO (PMID:11799113), (PMID:9130696) RGD PMID:9130696 PMID:11799113 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20295
    metabolic process 11722
      primary metabolic process 10273
        protein metabolic process 4699
          proteolysis 1589
            protein processing 264
              negative regulation of protein processing 21
                negative regulation of peptide hormone processing 0
                negative regulation of plasminogen activation 6
                negative regulation of protein processing in phagocytic vesicle 0
                negative regulation of protein processing involved in protein targeting to mitochondrion 1
                zymogen inhibition + 1
Path 2
Term Annotations click to browse term
  biological_process 20295
    biological regulation 13636
      regulation of biological process 13225
        regulation of metabolic process 6577
          regulation of biosynthetic process 5421
            regulation of cellular biosynthetic process 5371
              regulation of macromolecule biosynthetic process 5228
                regulation of gene expression 5113
                  regulation of protein maturation 66
                    regulation of protein processing 62
                      negative regulation of protein processing 21
                        negative regulation of peptide hormone processing 0
                        negative regulation of plasminogen activation 6
                        negative regulation of protein processing in phagocytic vesicle 0
                        negative regulation of protein processing involved in protein targeting to mitochondrion 1
                        zymogen inhibition + 1
paths to the root