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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein processing
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Accession:GO:0010955 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
Synonyms:exact_synonym: negative regulation of protein maturation by peptide bond cleavage



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negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp4 acid phosphatase 4 involved_in ISO (PMID:15219672) RGD PMID:15219672 NCBI chr 1:94,736,376...94,751,871
Ensembl chr 1:94,735,514...94,744,623
JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (MGI:3763814|PMID:17344476) RGD PMID:17344476 MGI:3763814 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO
ISS
(PMID:22445366)
GO_REF:0000024
RGD
UniProt
PMID:22445366 GO_REF:0000024 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Fmr1 FMRP translational regulator 1 IMP Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:21357679) RGD PMID:21357679 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764|MGI:97513 (MGI:4829577|PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5468848|PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107 MGI:5468848 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like involved_in ISO (PMID:19188362) RGD PMID:19188362 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IMP Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Snx12 sorting nexin 12 involved_in ISO (PMID:22709416) RGD PMID:22709416 NCBI chr  X:66,226,995...66,356,945
Ensembl chr  X:66,227,053...66,356,950
JBrowse link
G Tmem59 transmembrane protein 59 involved_in ISO (PMID:20427278) RGD PMID:20427278 NCBI chr 5:121,962,507...121,983,625
Ensembl chr 5:121,962,440...121,983,625
JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
GO_REF:0000024
(MGI:6258499|PMID:30249802)
UniProt
RGD
PMID:30249802 GO_REF:0000024 MGI:6258499 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin involved_in ISO
IBA
(PMID:2407243)
PMID:21873635
RGD PMID:2407243 PMID:21873635 RGD:13792537 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cst7 cystatin F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5910746 (MGI:5904382|PMID:28251676)
RGD PMID:28251676 PMID:21873635 MGI:5904382, RGD:13792537 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in ISO (PMID:11821383) RGD PMID:11821383 NCBI chr10:55,838,381...55,904,374 JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IMP
PMID:17292893
PMID:16639714
UniProt PMID:17292893 PMID:16639714 RGD:10047212, RGD:10047164 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l12 BCL2 like 12 involved_in ISO (PMID:22262180) RGD PMID:22262180 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
JBrowse link
G Fcmr Fc mu receptor acts_upstream_of_or_within ISO (MGI:3576402|PMID:15632112) RGD PMID:15632112 MGI:3576402 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IBA
IEA
(PMID:15509781)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:15509781 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2681362|PMID:14623868)
Ensembl
RGD
PMID:14623868 GO_REF:0000107 MGI:2681362 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpb2 carboxypeptidase B2 IMP RGD PMID:23369837 RGD:7243115 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Ctsz cathepsin Z involved_in ISO (PMID:19433310) RGD PMID:19433310 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645
JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:4418017|PMID:19855083)
(PMID:18835034), (PMID:19855083), (PMID:8508955)
Ensembl
RGD
PMID:8508955 PMID:18835034 PMID:19855083 PMID:21873635 GO_REF:0000107 MGI:4418017, RGD:13792537 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IBA
IEA
(PMID:19855083)
PMID:21873635
GO_REF:0000107
(MGI:4418017|PMID:19855083)
RGD
Ensembl
PMID:19855083 PMID:21873635 GO_REF:0000107 MGI:4418017, RGD:13792537 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:134998) RGD PMID:134998 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt4 sirtuin 4 IMP RGD PMID:24029877 RGD:9586053 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) involved_in ISO (PMID:11799113), (PMID:9130696) RGD PMID:9130696 PMID:11799113 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      primary metabolic process 10535
        protein metabolic process 5935
          proteolysis 1907
            protein processing 256
              negative regulation of protein processing 29
                negative regulation of peptide hormone processing 0
                negative regulation of plasminogen activation 6
                negative regulation of protein processing in phagocytic vesicle 0
                negative regulation of protein processing involved in protein targeting to mitochondrion 1
                negative regulation of sterol regulatory element binding protein cleavage 0
                zymogen inhibition + 8
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      organic substance metabolic process 11355
        macromolecule metabolic process 9812
          protein metabolic process 5935
            cellular protein metabolic process 5267
              regulation of cellular protein metabolic process 2510
                negative regulation of cellular protein metabolic process 1069
                  negative regulation of proteolysis 393
                    negative regulation of protein processing 29
                      negative regulation of peptide hormone processing 0
                      negative regulation of plasminogen activation 6
                      negative regulation of protein processing in phagocytic vesicle 0
                      negative regulation of protein processing involved in protein targeting to mitochondrion 1
                      negative regulation of sterol regulatory element binding protein cleavage 0
                      zymogen inhibition + 8
paths to the root