BAG2 (BAG cochaperone 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: BAG2 (BAG cochaperone 2) Pan paniscus
Analyze
Symbol: BAG2
Name: BAG cochaperone 2
RGD ID: 11735213
Description: ENCODES a protein that exhibits adenyl-nucleotide exchange factor activity (inferred); heat shock protein binding (inferred); identical protein binding (inferred); INVOLVED IN positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN axon (inferred); dendrite (inferred); dendritic microtubule (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BAG family molecular chaperone regulator 2; BCL2 associated athanogene 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2571,642,366 - 71,656,326 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1667,523,808 - 67,536,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0656,730,297 - 56,743,123 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1658,360,889 - 58,373,733 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl658,360,889 - 58,373,733 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BAG2BonoboCarpenter syndrome  ISORGD:13437448554872ClinVar Annotator: match by term: Acrocephalopolysyndactyly Type II | ClinVar Annotator: match by term: Carpenter more ...ClinVarPMID:25741868
BAG2BonoboCarpenter syndrome 1  ISORGD:13437448554872ClinVar Annotator: match by term: Carpenter syndrome 1ClinVarPMID:25741868


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BAG2Bonobonegative regulation of protein ubiquitination involved_inIEAUniProtKB:O95816|UniProtKB:Q91YN9|ensembl:ENSMUSP00000042009|ensembl:ENSP00000359727150520179 EnsemblGO_REF:0000107
BAG2Bonobopositive regulation of proteasomal protein catabolic process involved_inIEAUniProtKB:Q91YN9|ensembl:ENSMUSP00000042009150520179 EnsemblGO_REF:0000107
BAG2Bonobopositive regulation of proteasomal ubiquitin-dependent protein catabolic process NOT|involved_inISOUniProtKB:P106369068941 PMID:19228967ARUK-UCLPMID:19228967
BAG2Bonobopositive regulation of protein processing involved_inIEAUniProtKB:O95816|ensembl:ENSP00000359727150520179 EnsemblGO_REF:0000107
BAG2Bonoboprotein stabilization involved_inIEAPANTHER:PTN002643454150520179 TreeGrafterGO_REF:0000118
BAG2Bonoboprotein stabilization involved_inIEAUniProtKB:O95816|ensembl:ENSP00000359727150520179 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BAG2Bonoboaxon located_inIEAUniProtKB:Q91YN9|ensembl:ENSMUSP00000042009150520179 EnsemblGO_REF:0000107
BAG2Bonobodendrite located_inIEAUniProtKB:Q91YN9|ensembl:ENSMUSP00000042009150520179 EnsemblGO_REF:0000107
BAG2Bonobodendritic microtubule located_inIEAUniProtKB:Q91YN9|ensembl:ENSMUSP00000042009150520179 EnsemblGO_REF:0000107
BAG2Bonobomicrotubule located_inIEAUniProtKB:Q91YN9|ensembl:ENSMUSP00000042009150520179 EnsemblGO_REF:0000107
BAG2Bonoboprotein folding chaperone complex part_ofIEAUniProtKB:O95816|ensembl:ENSP00000359727150520179 EnsemblGO_REF:0000107

Molecular Function
1 to 20 of 26 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BAG2Bonoboadenyl-nucleotide exchange factor activity enablesIEAPANTHER:PTN002643454150520179 TreeGrafterGO_REF:0000118
BAG2Bonoboadenyl-nucleotide exchange factor activity enablesIEAInterPro:IPR037689150520179 InterProGO_REF:0000002
BAG2Bonoboadenyl-nucleotide exchange factor activity enablesIEAUniProtKB:O95816|ensembl:ENSP00000359727150520179 EnsemblGO_REF:0000107
BAG2Bonoboheat shock protein binding enablesIEAUniProtKB:Q91YN9|ensembl:ENSMUSP00000042009150520179 EnsemblGO_REF:0000107
BAG2Bonoboidentical protein binding enablesIEAUniProtKB:O95816|ensembl:ENSP00000359727150520179 EnsemblGO_REF:0000107
BAG2Bonoboprotein binding enablesISOUniProtKB:Q9NRI5-29068941 PMID:32296183IntActPMID:32296183
BAG2Bonoboprotein binding enablesISOUniProtKB:P040499068941 PMID:37045861IntActPMID:37045861
BAG2Bonoboprotein binding enablesISOUniProtKB:Q8AZK79068941 PMID:22810586IntActPMID:22810586
BAG2Bonoboprotein binding enablesISOUniProtKB:Q5S0079068941 PMID:24510904IntActPMID:24510904
BAG2Bonoboprotein binding enablesISOUniProtKB:P11142|UniProtKB:Q8AZK79068941 PMID:18457437IntActPMID:18457437
BAG2Bonoboprotein binding enablesISOUniProtKB:P04049|UniProtKB:Q131649068941 PMID:31980649IntActPMID:31980649
BAG2Bonoboprotein binding enablesISOUniProtKB:O950729068941 PMID:24981860IntActPMID:24981860
BAG2Bonoboprotein binding enablesISOUniProtKB:P53355|UniProtKB:Q5S0079068941 PMID:29513927IntActPMID:29513927
BAG2Bonoboprotein binding enablesISOUniProtKB:P0DMV8|UniProtKB:P0DMV9|UniProtKB:P111429068941 PMID:24318877UniProtPMID:24318877
BAG2Bonoboprotein binding enablesISOUniProtKB:P111429068941 PMID:16207813, PMID:22365833, PMID:29568061, PMID:30021884IntActPMID:16207813|PMID:22365833|PMID:29568061|PMID:30021884
BAG2Bonoboprotein binding enablesISOUniProtKB:P533559068941 PMID:25852190IntActPMID:25852190
BAG2Bonoboprotein binding enablesISOUniProtKB:P176129068941 PMID:35167623IntActPMID:35167623
BAG2Bonoboprotein binding enablesISOUniProtKB:P542539068941 PMID:25959826, PMID:32814053IntActPMID:25959826|PMID:32814053
BAG2Bonoboprotein binding enablesISOUniProtKB:O43765|UniProtKB:O95072|UniProtKB:P04049|UniProtKB:P58340|UniProtKB:Q03933|UniProtKB:Q15773|UniProtKB:Q96BE0|UniProtKB:Q99615|UniProtKB:Q9UNE79068941 PMID:25036637IntActPMID:25036637
BAG2Bonoboprotein binding enablesISOUniProtKB:Q996159068941 PMID:26496610, PMID:35271311IntActPMID:26496610|PMID:35271311
1 to 20 of 26 rows

PMID:22301074   PMID:30032202  



BAG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2571,642,366 - 71,656,326 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1667,523,808 - 67,536,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0656,730,297 - 56,743,123 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1658,360,889 - 58,373,733 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl658,360,889 - 58,373,733 (+)Ensemblpanpan1.1panPan2
BAG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38657,172,326 - 57,189,833 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl657,172,326 - 57,189,833 (+)EnsemblGRCh38hg38GRCh38
GRCh37657,037,124 - 57,054,631 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36657,145,293 - 57,157,694 (+)NCBINCBI36Build 36hg18NCBI36
Build 34657,145,292 - 57,157,692NCBI
Celera658,700,203 - 58,713,112 (+)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef656,871,161 - 56,884,070 (+)NCBIHuRef
CHM1_1657,037,430 - 57,050,339 (+)NCBICHM1_1
T2T-CHM13v2.0657,011,351 - 57,028,858 (+)NCBIT2T-CHM13v2.0
Bag2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,784,565 - 33,796,831 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,784,565 - 33,796,876 (-)EnsemblGRCm39 Ensembl
GRCm38133,745,484 - 33,757,750 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,745,484 - 33,757,795 (-)EnsemblGRCm38mm10GRCm38
MGSCv37133,802,329 - 33,814,595 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,690,030 - 33,702,309 (-)NCBIMGSCv36mm8
Celera133,520,517 - 33,532,756 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map112.81NCBI
Bag2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8943,465,993 - 43,476,637 (-)NCBIGRCr8
mRatBN7.2935,970,033 - 35,980,677 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl935,970,033 - 35,980,721 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx944,466,951 - 44,477,595 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0949,598,137 - 49,608,781 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0947,880,055 - 47,890,699 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0938,456,487 - 38,467,120 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl938,456,468 - 38,467,118 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0938,145,393 - 38,147,904 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4932,491,167 - 32,493,678 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera933,762,835 - 33,773,286 (-)NCBICelera
Cytogenetic Map9q21NCBI
Bag2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555022,984,233 - 2,994,457 (-)NCBIChiLan1.0ChiLan1.0
BAG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11224,353,549 - 24,369,190 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1224,353,663 - 24,368,350 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1224,283,590 - 24,299,229 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01224,893,036 - 24,908,696 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1224,893,052 - 24,908,693 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11224,390,264 - 24,405,914 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01224,491,610 - 24,506,382 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01224,623,002 - 24,638,655 (+)NCBIUU_Cfam_GSD_1.0
Bag2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494659,817,850 - 59,829,590 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364764,129,013 - 4,142,357 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364764,131,159 - 4,142,357 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl728,659,753 - 28,680,491 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1728,668,587 - 28,680,497 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2733,129,078 - 33,140,950 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BAG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11714,420,196 - 14,432,910 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1714,420,947 - 14,433,354 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605820,509,961 - 20,527,469 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bag2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475318,983,449 - 18,986,078 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSPPAT00000056352   ⟹   ENSPPAP00000033476
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl658,360,889 - 58,373,733 (+)Ensembl
RefSeq Acc Id: XM_003828922   ⟹   XP_003828970
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,642,366 - 71,656,326 (+)NCBI
NHGRI_mPanPan1667,523,808 - 67,536,531 (+)NCBI
Mhudiblu_PPA_v0656,730,297 - 56,743,123 (+)NCBI
PanPan1.1658,360,889 - 58,373,733 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034962277   ⟹   XP_034818168
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,642,882 - 71,656,326 (+)NCBI
NHGRI_mPanPan1667,524,317 - 67,536,531 (+)NCBI
Mhudiblu_PPA_v0656,730,675 - 56,743,123 (+)NCBI
RefSeq Acc Id: XM_034962278   ⟹   XP_034818169
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,642,863 - 71,656,326 (+)NCBI
NHGRI_mPanPan1667,524,298 - 67,536,531 (+)NCBI
Mhudiblu_PPA_v0656,730,423 - 56,743,123 (+)NCBI
RefSeq Acc Id: XM_055113687   ⟹   XP_054969662
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,643,050 - 71,656,326 (+)NCBI
NHGRI_mPanPan1667,524,481 - 67,536,531 (+)NCBI
RefSeq Acc Id: XM_055113688   ⟹   XP_054969663
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,643,048 - 71,656,326 (+)NCBI
NHGRI_mPanPan1667,524,481 - 67,536,531 (+)NCBI
RefSeq Acc Id: XM_055113689   ⟹   XP_054969664
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,643,022 - 71,656,326 (+)NCBI
NHGRI_mPanPan1667,524,457 - 67,536,531 (+)NCBI
RefSeq Acc Id: XM_055113690   ⟹   XP_054969665
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,643,041 - 71,656,326 (+)NCBI
NHGRI_mPanPan1667,524,476 - 67,536,531 (+)NCBI
RefSeq Acc Id: XM_055113692   ⟹   XP_054969667
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,643,051 - 71,656,326 (+)NCBI
NHGRI_mPanPan1667,524,482 - 67,536,531 (+)NCBI
RefSeq Acc Id: XM_063604935   ⟹   XP_063461005
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,643,051 - 71,656,326 (+)NCBI
RefSeq Acc Id: XM_063604936   ⟹   XP_063461006
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2571,643,051 - 71,656,326 (+)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: XP_003828970   ⟸   XM_003828922
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BVI9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034818169   ⟸   XM_034962278
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034818168   ⟸   XM_034962277
- Peptide Label: isoform X2
Ensembl Acc Id: ENSPPAP00000033476   ⟸   ENSPPAT00000056352
RefSeq Acc Id: XP_054969664   ⟸   XM_055113689
- Peptide Label: isoform X2
BAG



1 to 12 of 12 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000039605 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056352.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.890 UniProtKB/TrEMBL
InterPro BAG2 UniProtKB/TrEMBL
  BAG_domain UniProtKB/TrEMBL
KEGG Report pps:100986077 UniProtKB/TrEMBL
NCBI Gene BAG2 ENTREZGENE
PANTHER BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 UniProtKB/TrEMBL
  PTHR12334 UniProtKB/TrEMBL
PROSITE BAG UniProtKB/TrEMBL
SMART BAG UniProtKB/TrEMBL
UniProt A0A2R9BVI9 ENTREZGENE, UniProtKB/TrEMBL
1 to 12 of 12 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-26 BAG2  BAG cochaperone 2  BAG2  BCL2 associated athanogene 2  Symbol and/or name change 5135510 APPROVED