BAG2 (BAG cochaperone 2) - Rat Genome Database

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Gene: BAG2 (BAG cochaperone 2) Homo sapiens
Analyze
Symbol: BAG2
Name: BAG cochaperone 2
RGD ID: 1343744
HGNC Page HGNC:938
Description: Enables several functions, including adenyl-nucleotide exchange factor activity; identical protein binding activity; and transmembrane transporter binding activity. Involved in negative regulation of protein ubiquitination; positive regulation of protein processing; and protein stabilization. Part of protein folding chaperone complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: BAG family molecular chaperone regulator 2; BAG-2; BAG-family molecular chaperone regulator-2; bcl-2-associated athanogene 2; BCL2 associated athanogene 2; BCL2-associated athanogene 2; dJ417I1.2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); KIAA0576; MGC149462
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38657,172,326 - 57,189,833 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl657,172,326 - 57,189,833 (+)EnsemblGRCh38hg38GRCh38
GRCh37657,037,124 - 57,054,631 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36657,145,293 - 57,157,694 (+)NCBINCBI36Build 36hg18NCBI36
Build 34657,145,292 - 57,157,692NCBI
Celera658,700,203 - 58,713,112 (+)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef656,871,161 - 56,884,070 (+)NCBIHuRef
CHM1_1657,037,430 - 57,050,339 (+)NCBICHM1_1
T2T-CHM13v2.0657,011,351 - 57,028,858 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BAG2HumanCarpenter syndrome  IAGP (Homo sapiens) more ...8554872ClinVar more ...ClinVar 
BAG2HumanCarpenter syndrome  IAGP (Homo sapiens) more ...8554872ClinVar more ...ClinVarPMID:25741868
BAG2HumanCarpenter syndrome 1  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Carpenter syndrome 1ClinVarPMID:25741868
BAG2HumanCarpenter syndrome 1  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Carpenter syndrome 1ClinVar 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BAG2Human(+)-schisandrin B multiple interactionsISOBag2 (Rattus norvegicus)6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BAG2 mRNA]CTDPMID:31150632
BAG2Human(-)-epigallocatechin 3-gallate multiple interactionsEXP 6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of BAG2 mRNACTDPMID:22079256
BAG2Human1,2-dimethylhydrazine increases expressionISOBag2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of BAG2 mRNACTDPMID:22206623
BAG2Human17beta-estradiol affects expressionISOBag2 (Mus musculus)6480464Estradiol affects the expression of BAG2 mRNACTDPMID:15598610
BAG2Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of BAG2 mRNACTDPMID:20106945 and PMID:24758408
BAG2Human17beta-estradiol multiple interactionsEXP 6480464EGF protein promotes the reaction [Estradiol results in increased expression of BAG2 mRNA]CTDPMID:24758408
BAG2Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISOBag2 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in increased expression of BAG2 mRNACTDPMID:34747641
BAG2Human2-amino-14,16-dimethyloctadecan-3-ol decreases expressionEXP 64804642-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of BAG2 proteinCTDPMID:32044396
BAG2Human3-chloropropane-1,2-diol increases expressionISOBag2 (Rattus norvegicus)6480464alpha-Chlorohydrin results in increased expression of BAG2 proteinCTDPMID:34915118
BAG2Human3-isobutyl-1-methyl-7H-xanthine multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of BAG2 mRNACTDPMID:28628672
BAG2Human4,4'-diaminodiphenylmethane decreases expressionISOBag2 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of BAG2 mRNACTDPMID:18648102
BAG2Human4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of BAG2 proteinCTDPMID:34186270
BAG2Human4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid increases expressionEXP 6480464Am 580 results in increased expression of BAG2 mRNACTDPMID:16982809
BAG2Human4-hydroxyphenyl retinamide increases expressionISOBag2 (Mus musculus)6480464Fenretinide results in increased expression of BAG2 mRNACTDPMID:28973697
BAG2Human5-aza-2'-deoxycytidine multiple interactionsEXP 6480464TP53 protein affects the reaction [Decitabine results in decreased expression of BAG2 mRNA]CTDPMID:19363521
BAG2Human5-aza-2'-deoxycytidine decreases expressionEXP 6480464Decitabine results in decreased expression of BAG2 mRNACTDPMID:19363521
BAG2Humanacetamide decreases expressionISOBag2 (Rattus norvegicus)6480464acetamide results in decreased expression of BAG2 mRNACTDPMID:31881176
BAG2Humanacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of BAG2 mRNACTDPMID:32763439
BAG2Humanaflatoxin B1 decreases expressionISOBag2 (Mus musculus)6480464Aflatoxin B1 results in decreased expression of BAG2 mRNACTDPMID:19770486
BAG2Humanaflatoxin B1 decreases methylationEXP 6480464Aflatoxin B1 results in decreased methylation of BAG2 geneCTDPMID:27153756

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Biological Process
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Cellular Component
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Molecular Function
1 to 20 of 27 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BAG2Humanadenyl-nucleotide exchange factor activity enablesIDA 150520179 PMID:24318877UniProtPMID:24318877
BAG2Humanadenyl-nucleotide exchange factor activity enablesIBAPANTHER:PTN000269264 and UniProtKB:O95816150520179 GO_CentralGO_REF:0000033
BAG2Humanadenyl-nucleotide exchange factor activity enablesIEAInterPro:IPR037689150520179 InterProGO_REF:0000002
BAG2Humanheat shock protein binding enablesIEAUniProtKB:Q91YN9 and ensembl:ENSMUSP00000042009150520179 EnsemblGO_REF:0000107
BAG2Humanidentical protein binding enablesIPIUniProtKB:O95816150520179 PMID:22365833 more ...IntActPMID:22365833 more ...
BAG2Humanprotein binding enablesIPIUniProtKB:P11142 more ...150520179 PMID:33961781IntActPMID:33961781
BAG2Humanprotein binding enablesIPIUniProtKB:P04049150520179 PMID:37045861IntActPMID:37045861
BAG2Humanprotein binding enablesIPIUniProtKB:P53355 and UniProtKB:Q5S007150520179 PMID:29513927IntActPMID:29513927
BAG2Humanprotein binding enablesIPIUniProtKB:P54253150520179 PMID:25959826 and PMID:32814053IntActPMID:25959826 and PMID:32814053
BAG2Humanprotein binding enablesIPIUniProtKB:O95072150520179 PMID:24981860IntActPMID:24981860
BAG2Humanprotein binding enablesIPIUniProtKB:P53355150520179 PMID:25852190IntActPMID:25852190
BAG2Humanprotein binding enablesIPIUniProtKB:Q5S007150520179 PMID:24510904IntActPMID:24510904
BAG2Humanprotein binding enablesIPIUniProtKB:P0DMV8 more ...150520179 PMID:24318877UniProtPMID:24318877
BAG2Humanprotein binding enablesIPIUniProtKB:P11142 and UniProtKB:Q8AZK7150520179 PMID:18457437IntActPMID:18457437
BAG2Humanprotein binding enablesIPIUniProtKB:Q9NRI5-2150520179 PMID:32296183IntActPMID:32296183
BAG2Humanprotein binding enablesIPIUniProtKB:P04049 and UniProtKB:Q13164150520179 PMID:31980649IntActPMID:31980649
BAG2Humanprotein binding enablesIPIUniProtKB:P11142150520179 PMID:16207813 more ...IntActPMID:16207813 more ...
BAG2Humanprotein binding enablesIPIUniProtKB:Q8AZK7150520179 PMID:22810586IntActPMID:22810586
BAG2Humanprotein binding enablesIPIUniProtKB:P17612150520179 PMID:35167623IntActPMID:35167623
BAG2Humanprotein binding enablesIPIUniProtKB:O43765 more ...150520179 PMID:25036637IntActPMID:25036637
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Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
BAG2HumanEndoplasmic Reticulum-associated degradation pathway  IEA 6907045 KEGGhsa:04141

#
Reference Title
Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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PMID:9873015   PMID:9873016   PMID:11076863   PMID:11230166   PMID:11256614   PMID:12477932   PMID:14574404   PMID:14702039   PMID:15271996   PMID:15489334   PMID:15489336   PMID:16159877  
PMID:16169850   PMID:16196087   PMID:16207813   PMID:16344560   PMID:16381901   PMID:17110338   PMID:17203973   PMID:17353931   PMID:17569659   PMID:18457437   PMID:19156129   PMID:19228967  
PMID:19738201   PMID:19875381   PMID:20020773   PMID:20547759   PMID:21081666   PMID:21139048   PMID:21145461   PMID:21654808   PMID:21873635   PMID:21906983   PMID:21963094   PMID:21987572  
PMID:22365833   PMID:22451720   PMID:22505724   PMID:22810586   PMID:22863883   PMID:22912744   PMID:23000965   PMID:23275444   PMID:23349634   PMID:23383273   PMID:23398456   PMID:23402259  
PMID:23438482   PMID:23443559   PMID:23508102   PMID:23667531   PMID:23686814   PMID:23752268   PMID:23824909   PMID:23956138   PMID:24244333   PMID:24255178   PMID:24318877   PMID:24332808  
PMID:24383081   PMID:24510904   PMID:24711643   PMID:24811749   PMID:24816145   PMID:24981860   PMID:25006867   PMID:25015289   PMID:25036637   PMID:25144556   PMID:25147182   PMID:25324306  
PMID:25356737   PMID:25416956   PMID:25437307   PMID:25452129   PMID:25499913   PMID:25544563   PMID:25756610   PMID:25798074   PMID:25817432   PMID:25852190   PMID:25900982   PMID:25959826  
PMID:25963833   PMID:25985852   PMID:26208804   PMID:26271008   PMID:26344197   PMID:26485645   PMID:26496610   PMID:26549023   PMID:26618866   PMID:26638075   PMID:26687479   PMID:26725010  
PMID:26752685   PMID:26841866   PMID:26972000   PMID:26990986   PMID:27187154   PMID:27320910   PMID:27545878   PMID:27591049   PMID:27609421   PMID:27684187   PMID:27807478   PMID:27880917  
PMID:28042827   PMID:28089446   PMID:28330616   PMID:28386764   PMID:28515276   PMID:28536620   PMID:28775156   PMID:28977666   PMID:29117863   PMID:29128334   PMID:29229926   PMID:29331416  
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BAG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38657,172,326 - 57,189,833 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl657,172,326 - 57,189,833 (+)EnsemblGRCh38hg38GRCh38
GRCh37657,037,124 - 57,054,631 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36657,145,293 - 57,157,694 (+)NCBINCBI36Build 36hg18NCBI36
Build 34657,145,292 - 57,157,692NCBI
Celera658,700,203 - 58,713,112 (+)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef656,871,161 - 56,884,070 (+)NCBIHuRef
CHM1_1657,037,430 - 57,050,339 (+)NCBICHM1_1
T2T-CHM13v2.0657,011,351 - 57,028,858 (+)NCBIT2T-CHM13v2.0
Bag2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,784,565 - 33,796,831 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,784,565 - 33,796,876 (-)EnsemblGRCm39 Ensembl
GRCm38133,745,484 - 33,757,750 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,745,484 - 33,757,795 (-)EnsemblGRCm38mm10GRCm38
MGSCv37133,802,329 - 33,814,595 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,690,030 - 33,702,309 (-)NCBIMGSCv36mm8
Celera133,520,517 - 33,532,756 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map112.81NCBI
Bag2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8943,465,993 - 43,476,637 (-)NCBIGRCr8
mRatBN7.2935,970,033 - 35,980,677 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl935,970,033 - 35,980,721 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx944,466,951 - 44,477,595 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0949,598,137 - 49,608,781 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0947,880,055 - 47,890,699 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0938,456,487 - 38,467,120 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl938,456,468 - 38,467,118 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0938,145,393 - 38,147,904 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4932,491,167 - 32,493,678 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera933,762,835 - 33,773,286 (-)NCBICelera
Cytogenetic Map9q21NCBI
Bag2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555022,984,233 - 2,994,457 (-)NCBIChiLan1.0ChiLan1.0
BAG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2571,642,366 - 71,656,326 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1667,523,808 - 67,536,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0656,730,297 - 56,743,123 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1658,360,889 - 58,373,733 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl658,360,889 - 58,373,733 (+)Ensemblpanpan1.1panPan2
BAG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11224,353,549 - 24,369,190 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1224,353,663 - 24,368,350 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1224,283,590 - 24,299,229 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01224,893,036 - 24,908,696 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1224,893,052 - 24,908,693 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11224,390,264 - 24,405,914 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01224,491,610 - 24,506,382 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01224,623,002 - 24,638,655 (+)NCBIUU_Cfam_GSD_1.0
Bag2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494659,817,850 - 59,829,590 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364764,129,013 - 4,142,357 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364764,131,159 - 4,142,357 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl728,659,753 - 28,680,491 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1728,668,587 - 28,680,497 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2733,129,078 - 33,140,950 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BAG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11714,420,196 - 14,432,910 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1714,420,947 - 14,433,354 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605820,509,961 - 20,527,469 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bag2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475318,983,449 - 18,986,078 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in BAG2
42 total Variants

1 to 10 of 58 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 6p12.1-11.2(chr6:56312924-57306212)x1 copy number loss See cases [RCV000133851] Chr6:56312924..57306212 [GRCh38]
Chr6:56177722..57171010 [GRCh37]
Chr6:56285681..57278969 [NCBI36]
Chr6:6p12.1-11.2
uncertain significance
GRCh38/hg38 6p12.3-11.2(chr6:50971182-57432788)x1 copy number loss See cases [RCV000134922] Chr6:50971182..57432788 [GRCh38]
Chr6:50938895..57297586 [GRCh37]
Chr6:51046854..57405545 [NCBI36]
Chr6:6p12.3-11.2
pathogenic
GRCh38/hg38 6p12.1-11.2(chr6:56639682-57432788)x3 copy number gain See cases [RCV000135785] Chr6:56639682..57432788 [GRCh38]
Chr6:56504480..57297586 [GRCh37]
Chr6:56612439..57405545 [NCBI36]
Chr6:6p12.1-11.2
likely benign|uncertain significance
GRCh38/hg38 6p12.1-q12(chr6:53931543-68149750)x3 copy number gain See cases [RCV000137097] Chr6:53931543..68149750 [GRCh38]
Chr6:53796341..68859642 [GRCh37]
Chr6:53904300..68916363 [NCBI36]
Chr6:6p12.1-q12
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p11.2(chr6:57034009-57185345)x3 copy number gain not provided [RCV000745746] Chr6:57034009..57185345 [GRCh37]
Chr6:6p11.2
benign
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Predicted Target Of
Summary Value
Count of predictions:1821
Count of miRNA genes:794
Interacting mature miRNAs:911
Transcripts:ENST00000370693, ENST00000545080
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

RH46599  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37657,049,468 - 57,049,648UniSTSGRCh37
Build 36657,157,427 - 57,157,607RGDNCBI36
Celera658,712,567 - 58,712,747RGD
Cytogenetic Map6p12.1-p11.2UniSTS
HuRef656,883,525 - 56,883,705UniSTS
AL035194  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37657,046,833 - 57,046,981UniSTSGRCh37
Build 36657,154,792 - 57,154,940RGDNCBI36
Celera658,709,932 - 58,710,080RGD
Cytogenetic Map6p12.1-p11.2UniSTS
HuRef656,880,890 - 56,881,038UniSTS
SHGC-34200  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37657,049,224 - 57,049,361UniSTSGRCh37
Build 36657,157,183 - 57,157,320RGDNCBI36
Celera658,712,323 - 58,712,460RGD
Cytogenetic Map6p12.1-p11.2UniSTS
HuRef656,883,281 - 56,883,418UniSTS
TNG Radiation Hybrid Map628265.0UniSTS
GeneMap99-GB4 RH Map6221.18UniSTS
Whitehead-RH Map6306.3UniSTS
NCBI RH Map6722.7UniSTS
BAG2_7951  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37657,048,583 - 57,049,505UniSTSGRCh37
Build 36657,156,542 - 57,157,464RGDNCBI36
Celera658,711,682 - 58,712,604RGD
HuRef656,882,640 - 56,883,562UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2436 2788 2251 4955 1724 2348 5 622 1950 465 2268 7299 6468 53 3718 850 1743 1614 172


1 to 23 of 23 rows
RefSeq Transcripts NM_004282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF095192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL031321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL050287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL136311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA442969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR533496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA874388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 23 of 23 rows

Ensembl Acc Id: ENST00000370693   ⟹   ENSP00000359727
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl657,172,326 - 57,189,833 (+)Ensembl
RefSeq Acc Id: NM_004282   ⟹   NP_004273
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38657,172,326 - 57,189,833 (+)NCBI
GRCh37657,037,104 - 57,050,013 (+)RGD
GRCh37657,037,104 - 57,050,013 (+)NCBI
Build 36657,145,293 - 57,157,694 (+)NCBI Archive
Celera658,700,203 - 58,713,112 (+)RGD
HuRef656,871,161 - 56,884,070 (+)ENTREZGENE
CHM1_1657,037,430 - 57,050,339 (+)NCBI
T2T-CHM13v2.0657,011,351 - 57,028,858 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005249490   ⟹   XP_005249547
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38657,172,870 - 57,189,833 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011514999   ⟹   XP_011513301
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38657,172,870 - 57,189,833 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054356854   ⟹   XP_054212829
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0657,011,895 - 57,028,858 (+)NCBI
RefSeq Acc Id: XM_054356855   ⟹   XP_054212830
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0657,011,895 - 57,028,858 (+)NCBI
RefSeq Acc Id: NP_004273   ⟸   NM_004282
- UniProtKB: Q08AS9 (UniProtKB/Swiss-Prot),   B4DXE2 (UniProtKB/Swiss-Prot),   Q6FID0 (UniProtKB/Swiss-Prot),   O95816 (UniProtKB/Swiss-Prot),   B3KM36 (UniProtKB/TrEMBL),   B3KN59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005249547   ⟸   XM_005249490
- Peptide Label: isoform X1
- UniProtKB: B3KM36 (UniProtKB/TrEMBL),   B3KN59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011513301   ⟸   XM_011514999
- Peptide Label: isoform X1
- UniProtKB: B3KM36 (UniProtKB/TrEMBL),   B3KN59 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000359727   ⟸   ENST00000370693
RefSeq Acc Id: XP_054212829   ⟸   XM_054356854
- Peptide Label: isoform X1
- UniProtKB: B3KM36 (UniProtKB/TrEMBL),   B3KN59 (UniProtKB/TrEMBL)
BAG

Name Modeler Protein Id AA Range Protein Structure
AF-O95816-F1-model_v2 AlphaFold O95816 1-211 view protein structure

RGD ID:6803779
Promoter ID:HG_KWN:53942
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_004282,   OTTHUMT00000041045
Position:
Human AssemblyChrPosition (strand)Source
Build 36657,145,061 - 57,145,561 (+)MPROMDB
RGD ID:6814758
Promoter ID:HG_XEF:6900
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:NM_001006728
Position:
Human AssemblyChrPosition (strand)Source
Build 36657,155,916 - 57,156,416 (+)MPROMDB
RGD ID:7208401
Promoter ID:EPDNEW_H9947
Type:initiation region
Name:BAG2_3
Description:BCL2 associated athanogene 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9948  EPDNEW_H9949  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38657,170,088 - 57,170,148EPDNEW
RGD ID:7208405
Promoter ID:EPDNEW_H9948
Type:initiation region
Name:BAG2_1
Description:BCL2 associated athanogene 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9947  EPDNEW_H9949  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38657,172,326 - 57,172,386EPDNEW
RGD ID:7208407
Promoter ID:EPDNEW_H9949
Type:initiation region
Name:BAG2_2
Description:BCL2 associated athanogene 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9947  EPDNEW_H9948  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38657,172,641 - 57,172,701EPDNEW


1 to 27 of 27 rows
Database
Acc Id
Source(s)
COSMIC BAG2 COSMIC
Ensembl Genes ENSG00000112208 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000370693 ENTREZGENE
  ENST00000370693.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.890 UniProtKB/Swiss-Prot
GTEx ENSG00000112208 GTEx
HGNC ID HGNC:938 ENTREZGENE
Human Proteome Map BAG2 Human Proteome Map
InterPro BAG2 UniProtKB/Swiss-Prot
  BAG_domain UniProtKB/Swiss-Prot
KEGG Report hsa:9532 UniProtKB/Swiss-Prot
NCBI Gene 9532 ENTREZGENE
OMIM 603882 OMIM
PANTHER BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2 UniProtKB/Swiss-Prot
  PTHR12334 UniProtKB/Swiss-Prot
PharmGKB PA25238 PharmGKB
PROSITE BAG UniProtKB/Swiss-Prot
SMART BAG UniProtKB/Swiss-Prot
UniProt B3KM36 ENTREZGENE, UniProtKB/TrEMBL
  B3KN59 ENTREZGENE, UniProtKB/TrEMBL
  B4DXE2 ENTREZGENE
  BAG2_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q08AS9 ENTREZGENE
  Q6FID0 ENTREZGENE
UniProt Secondary B4DXE2 UniProtKB/Swiss-Prot
  Q08AS9 UniProtKB/Swiss-Prot
  Q6FID0 UniProtKB/Swiss-Prot
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-08 BAG2  BAG cochaperone 2  BAG2  BCL2 associated athanogene 2  Symbol and/or name change 5135510 APPROVED
2015-11-24 BAG2  BCL2 associated athanogene 2  BAG2  BCL2-associated athanogene 2  Symbol and/or name change 5135510 APPROVED