SHH (sonic hedgehog signaling molecule) - Rat Genome Database

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Gene: SHH (sonic hedgehog signaling molecule) Pan paniscus
Analyze
Symbol: SHH
Name: sonic hedgehog signaling molecule
RGD ID: 11681032
Description: ENCODES a protein that exhibits hydrolase activity (ortholog); INVOLVED IN alpha-tubulin acetylation (ortholog); cell population proliferation (ortholog); cellular response to L-glutamate (ortholog); PARTICIPATES IN altered Hedgehog signaling pathway; forkhead class A signaling pathway; glypican signaling pathway; ASSOCIATED WITH acrocallosal syndrome (ortholog); Anorectal Malformations (ortholog); atrioventricular septal defect (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sonic hedgehog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26192,227,225 - 192,240,917 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1744,237,491 - 44,251,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07147,400,112 - 147,414,036 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17159,116,966 - 159,126,660 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7159,114,666 - 159,126,651 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acrocallosal syndrome  (ISO)
Anorectal Malformations  (ISO)
atrioventricular septal defect  (ISO)
autism spectrum disorder  (ISO)
autistic disorder  (ISO)
basal cell carcinoma  (ISO)
biliary atresia  (ISO)
brachydactyly type A1  (ISO)
chronic kidney disease  (ISO)
cleft palate  (ISO)
colorectal cancer  (ISO)
Congenital Limb Deformities  (ISO)
demyelinating disease  (ISO)
esophageal atresia/tracheoesophageal fistula  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Eye Abnormalities  (ISO)
Facial Dysmorphism with Multiple Malformations  (ISO)
Failure to Thrive  (ISO)
Fluoride Poisoning  (ISO)
focal segmental glomerulosclerosis  (ISO)
gastrointestinal stromal tumor  (ISO)
genetic disease  (ISO)
hepatocellular carcinoma  (ISO)
Hirschsprung's disease  (ISO)
holoprosencephaly  (ISO)
holoprosencephaly 3  (ISO)
Hyperoxic Lung Injury  (ISO)
hypoplastic or aplastic tibia with polydactyly  (ISO)
hypothyroidism  (ISO)
IgA glomerulonephritis  (ISO)
Isolated Microphthalmia with Coloboma 5  (ISO)
Kidney Reperfusion Injury  (ISO)
membranous glomerulonephritis  (ISO)
microphthalmia  (ISO)
middle cerebral artery infarction  (ISO)
multiple sclerosis  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
neurodevelopmental disorder with dysmorphic facies and distal limb anomalies  (ISO)
nevoid basal cell carcinoma syndrome  (ISO)
ocular hypertension  (ISO)
Parkinsonism  (ISO)
Partial Agenesis of Corpus Callosum  (ISO)
Patterson Stevenson Syndrome  (ISO)
Peripheral Nerve Injuries  (ISO)
Persistent Cloaca  (ISO)
polydactyly  (ISO)
pre-malignant neoplasm  (ISO)
preaxial polydactyly II  (ISO)
primary progressive multiple sclerosis  (ISO)
Schizencephaly  (ISO)
secondary Parkinson disease  (ISO)
septooptic dysplasia  (ISO)
solitary median maxillary central incisor  (ISO)
Spinal Cord Injuries  (ISO)
stomach cancer  (ISO)
Subarachnoid Hemorrhage  (ISO)
syndactyly type 4  (ISO)
temporal lobe epilepsy  (ISO)
transient cerebral ischemia  (ISO)
ureteral obstruction  (ISO)
VACTERL association  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
alpha-beta T cell differentiation  (IEA)
alpha-tubulin acetylation  (ISO)
anatomical structure formation involved in morphogenesis  (IEA)
androgen metabolic process  (IEA)
angiogenesis  (IEA)
animal organ development  (IEA)
animal organ formation  (IEA)
anterior/posterior pattern specification  (IEA)
apoptotic signaling pathway  (IEA)
artery development  (IEA)
astrocyte differentiation  (IEA)
axon guidance  (IEA)
Bergmann glial cell differentiation  (IEA)
blood coagulation  (IEA)
branching involved in blood vessel morphogenesis  (IEA)
branching involved in prostate gland morphogenesis  (IEA)
branching involved in salivary gland morphogenesis  (IEA)
branching involved in ureteric bud morphogenesis  (IEA)
branching morphogenesis of an epithelial tube  (IEA)
bud outgrowth involved in lung branching  (IEA)
camera-type eye development  (IEA)
canonical Wnt signaling pathway  (IEA)
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment  (IEA)
cell development  (IEA)
cell fate commitment  (IEA)
cell fate specification  (IEA)
cell migration  (IEA)
cell population proliferation  (IEA,ISO)
cell proliferation in external granule layer  (IEA)
cell-cell signaling  (IEA)
cellular response to L-glutamate  (ISO)
cellular response to lithium ion  (IEA)
central nervous system development  (IEA)
cerebellar granule cell precursor proliferation  (IEA,ISO)
commissural neuron axon guidance  (ISO)
determination of left/right asymmetry in lateral mesoderm  (IEA)
determination of left/right symmetry  (IEA)
developmental growth  (IEA)
digestive tract mesoderm development  (ISO)
digestive tract morphogenesis  (IEA)
dorsal/ventral neural tube patterning  (IEA,ISO)
dorsal/ventral pattern formation  (IEA)
ectoderm development  (IEA)
embryonic digestive tract morphogenesis  (IEA)
embryonic digit morphogenesis  (IEA,ISO)
embryonic foregut morphogenesis  (IEA)
embryonic forelimb morphogenesis  (IEA)
embryonic hindlimb morphogenesis  (IEA)
embryonic limb morphogenesis  (IEA)
embryonic morphogenesis  (IEA)
embryonic organ development  (IEA)
embryonic skeletal system development  (IEA)
endocytosis  (IEA)
epithelial cell proliferation  (IEA)
epithelial cell proliferation involved in prostate gland development  (IEA)
epithelial cell proliferation involved in salivary gland morphogenesis  (IEA)
epithelial tube branching involved in lung morphogenesis  (IEA,ISO)
epithelial-mesenchymal cell signaling  (IEA)
epithelial-mesenchymal signaling involved in prostate gland development  (IEA)
establishment of epithelial cell polarity  (IEA)
forebrain development  (IEA)
forebrain regionalization  (IEA)
formation of anatomical boundary  (IEA)
fungiform papilla development  (ISO)
fungiform papilla formation  (ISO)
fungiform papilla morphogenesis  (ISO)
gene expression  (IEA,ISO)
hair follicle development  (IEA)
hair follicle morphogenesis  (IEA)
heart development  (IEA)
heart looping  (IEA,ISO)
hindbrain development  (IEA)
hindgut morphogenesis  (IEA)
inner ear development  (IEA)
intein-mediated protein splicing  (IEA)
intermediate filament organization  (IEA)
kidney development  (IEA)
left lung development  (IEA)
limb bud formation  (IEA)
limb development  (IEA)
liver regeneration  (ISO)
lung development  (IEA)
lung epithelium development  (IEA)
lung lobe morphogenesis  (IEA)
lung morphogenesis  (IEA)
lung-associated mesenchyme development  (IEA)
lymphoid progenitor cell differentiation  (IEA)
male genitalia development  (IEA)
male genitalia morphogenesis  (ISO)
mesenchymal cell apoptotic process  (IEA)
mesenchymal cell proliferation  (IEA)
mesenchymal cell proliferation involved in lung development  (IEA)
mesenchymal smoothened signaling pathway involved in prostate gland development  (IEA)
metanephric collecting duct development  (IEA)
metanephric mesenchymal cell proliferation involved in metanephros development  (IEA)
metanephros development  (IEA)
midbrain development  (IEA)
myoblast differentiation  (IEA)
myotube differentiation  (IEA)
negative regulation of alpha-beta T cell differentiation  (IEA)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of canonical Wnt signaling pathway  (IEA)
negative regulation of cell migration  (IEA)
negative regulation of cellular process  (ISO)
negative regulation of cholesterol efflux  (IEA)
negative regulation of dopaminergic neuron differentiation  (IEA)
negative regulation of gene expression  (IEA)
negative regulation of kidney smooth muscle cell differentiation  (IEA)
negative regulation of mesenchymal cell apoptotic process  (IEA)
negative regulation of neuron differentiation  (IEA)
negative regulation of proteasomal ubiquitin-dependent protein catabolic process  (IEA)
negative regulation of protein catabolic process  (IEA)
negative regulation of T cell differentiation in thymus  (IEA)
negative regulation of T cell proliferation  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
negative regulation of transcription elongation by RNA polymerase II  (IEA)
negative regulation of ureter smooth muscle cell differentiation  (IEA)
negative regulation of Wnt signaling pathway  (IEA)
negative thymic T cell selection  (IEA)
neural crest cell migration  (IEA)
neural tube formation  (ISO)
neuroblast proliferation  (IEA,ISO)
neuron differentiation  (IEA)
neuron fate commitment  (IEA)
odontogenesis  (IEA)
odontogenesis of dentin-containing tooth  (IEA)
oligodendrocyte development  (IEA)
oligodendrocyte differentiation  (IEA)
osteoblast development  (IEA)
pancreas development  (IEA)
pattern specification process  (IEA)
polarity specification of anterior/posterior axis  (IEA)
positive regulation of alpha-beta T cell differentiation  (IEA)
positive regulation of astrocyte differentiation  (IEA)
positive regulation of cell division  (IEA)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of cerebellar granule cell precursor proliferation  (IEA)
positive regulation of DNA-templated transcription  (IEA,ISO)
positive regulation of endothelial cell chemotaxis  (ISO)
positive regulation of epithelial cell proliferation  (IEA)
positive regulation of epithelial cell proliferation involved in prostate gland development  (IEA)
positive regulation of gene expression  (IEA,ISO)
positive regulation of immature T cell proliferation in thymus  (IEA)
positive regulation of kidney smooth muscle cell differentiation  (IEA)
positive regulation of mesenchymal cell proliferation  (IEA)
positive regulation of mesenchymal cell proliferation involved in ureter development  (IEA)
positive regulation of neuroblast proliferation  (IEA,ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of neurotrophin production  (ISO)
positive regulation of oligodendrocyte differentiation  (IEA)
positive regulation of oligodendrocyte progenitor proliferation  (ISO)
positive regulation of penile erection  (ISO)
positive regulation of photoreceptor cell differentiation  (ISO)
positive regulation of protein import into nucleus  (IEA)
positive regulation of sclerotome development  (IEA)
positive regulation of skeletal muscle cell proliferation  (IEA)
positive regulation of skeletal muscle tissue development  (IEA)
positive regulation of smoothened signaling pathway  (IEA)
positive regulation of sprouting angiogenesis  (ISO)
positive regulation of striated muscle cell differentiation  (IEA)
positive regulation of T cell differentiation in thymus  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of ureter smooth muscle cell differentiation  (IEA)
positive regulation of Wnt signaling pathway  (IEA)
positive thymic T cell selection  (IEA)
primary prostatic bud elongation  (IEA)
prostate epithelial cord elongation  (IEA)
prostate gland development  (IEA,ISO)
prostatic bud formation  (ISO)
protein autoprocessing  (IEA)
protein import into nucleus  (IEA)
protein localization to nucleus  (IEA)
proteolysis  (IEA)
regulation of cell population proliferation  (IEA)
regulation of cerebellar granule cell precursor proliferation  (ISO)
regulation of developmental process  (IEA)
regulation of DNA-templated transcription  (IEA)
regulation of epithelial cell differentiation  (ISO)
regulation of epithelial cell proliferation involved in prostate gland development  (IEA)
regulation of gene expression  (IEA)
regulation of glial cell proliferation  (IEA)
regulation of mesenchymal cell proliferation involved in prostate gland development  (IEA)
regulation of odontogenesis  (IEA)
regulation of prostatic bud formation  (IEA)
regulation of protein localization to nucleus  (IEA)
regulation of proteolysis  (IEA)
regulation of stem cell proliferation  (IEA)
respiratory tube development  (IEA)
response to axon injury  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to hypoxia  (ISO)
response to retinoic acid  (ISO)
right lung development  (IEA)
roof of mouth development  (IEA)
salivary gland cavitation  (IEA)
self proteolysis  (IEA)
skeletal muscle cell proliferation  (IEA)
skeletal muscle fiber differentiation  (IEA)
skeletal muscle tissue development  (IEA)
skin development  (IEA)
smooth muscle tissue development  (IEA)
smoothened signaling pathway  (IEA)
somite development  (IEA)
spinal cord dorsal/ventral patterning  (IEA)
spinal cord motor neuron differentiation  (IEA)
stem cell development  (IEA)
stem cell proliferation  (IEA)
striated muscle cell differentiation  (IEA)
striated muscle tissue development  (IEA)
T cell differentiation in thymus  (IEA,ISO)
T cell proliferation  (IEA)
telencephalon regionalization  (IEA,ISO)
thalamus development  (IEA)
thymus development  (IEA)
thyroid gland development  (IEA)
tissue development  (IEA)
tongue development  (ISO)
tongue morphogenesis  (ISO)
trachea development  (IEA)
trachea morphogenesis  (IEA)
tracheoesophageal septum formation  (IEA)
trunk neural crest cell migration  (IEA)
tube development  (IEA)
vasculature development  (IEA)
vasculogenesis  (IEA)
ventral spinal cord interneuron specification  (ISO)
zona limitans intrathalamica formation  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SHH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26192,227,225 - 192,240,917 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1744,237,491 - 44,251,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07147,400,112 - 147,414,036 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17159,116,966 - 159,126,660 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7159,114,666 - 159,126,651 (-)Ensemblpanpan1.1panPan2
SHH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387155,799,980 - 155,812,463 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7155,799,980 - 155,812,463 (-)EnsemblGRCh38hg38GRCh38
GRCh377155,592,674 - 155,605,157 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367155,288,319 - 155,297,728 (-)NCBINCBI36Build 36hg18NCBI36
Build 347155,095,033 - 155,104,443NCBI
Celera7150,021,217 - 150,030,626 (-)NCBICelera
Cytogenetic Map7q36.3NCBI
HuRef7149,327,101 - 149,336,513 (-)NCBIHuRef
CHM1_17155,604,000 - 155,613,409 (-)NCBICHM1_1
T2T-CHM13v2.07156,983,127 - 156,995,607 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27154,827,119 - 154,836,528 (-)NCBI
Shh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39528,661,838 - 28,672,099 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl528,661,813 - 28,672,254 (-)EnsemblGRCm39 Ensembl
GRCm38528,456,840 - 28,467,101 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl528,456,815 - 28,467,256 (-)EnsemblGRCm38mm10GRCm38
MGSCv37528,783,380 - 28,793,641 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36528,787,627 - 28,797,875 (-)NCBIMGSCv36mm8
Celera525,997,895 - 26,008,156 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map514.39NCBI
Shh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr847,687,872 - 7,697,025 (+)NCBIGRCr8
mRatBN7.246,954,017 - 6,963,170 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl46,954,017 - 6,963,170 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx411,962,609 - 11,971,762 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.047,776,827 - 7,785,980 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.046,123,054 - 6,132,207 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04718,538 - 727,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4718,538 - 727,691 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04711,420 - 720,573 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.442,200,504 - 2,209,657 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.142,200,503 - 2,209,657 (+)NCBI
Celera43,316,537 - 3,325,690 (-)NCBICelera
Cytogenetic Map4q11NCBI
Shh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554918,647,133 - 8,657,381 (-)NCBIChiLan1.0ChiLan1.0
SHH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,650,553 - 18,663,571 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1618,484,809 - 18,662,903 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1619,286,449 - 19,295,913 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01620,382,879 - 20,392,367 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1620,382,707 - 20,392,037 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11618,753,210 - 18,762,671 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01619,333,131 - 19,342,583 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01619,386,812 - 19,396,258 (-)NCBIUU_Cfam_GSD_1.0
Shh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051182,860,455 - 2,871,247 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493652710,033,299 - 10,042,599 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493652710,033,095 - 10,042,713 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl182,545,994 - 2,555,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1182,546,202 - 2,555,484 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2182,664,794 - 2,673,805 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SHH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121123,929,937 - 123,942,451 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21123,932,900 - 123,942,395 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607220,134,625 - 20,147,164 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248002,203,393 - 2,212,068 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248002,202,986 - 2,215,309 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000043349   ⟹   ENSPPAP00000020554
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7159,114,666 - 159,121,170 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000043352   ⟹   ENSPPAP00000020557
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7159,116,966 - 159,126,651 (-)Ensembl
RefSeq Acc Id: XM_034965340   ⟹   XP_034821231
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26192,227,225 - 192,240,917 (-)NCBI
NHGRI_mPanPan1744,237,491 - 44,251,151 (-)NCBI
Mhudiblu_PPA_v07147,400,112 - 147,414,036 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034821231 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000020554.1
  ENSPPAP00000020557.1
RefSeq Acc Id: XP_034821231   ⟸   XM_034965340
- UniProtKB: A0A2R9ATB4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000020554   ⟸   ENSPPAT00000043349
Ensembl Acc Id: ENSPPAP00000020557   ⟸   ENSPPAT00000043352
Protein Domains
Hedgehog N-terminal signalling   Hint


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033504 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043349.1 UniProtKB/TrEMBL
  ENSPPAT00000043352.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1380.10 UniProtKB/TrEMBL
  Hedgehog/Intein (Hint) domain UniProtKB/TrEMBL
InterPro Hedgehog UniProtKB/TrEMBL
  Hedgehog_Hint UniProtKB/TrEMBL
  Hedgehog_sig/DD-Pept_Zn-bd_sf UniProtKB/TrEMBL
  Hedgehog_Signaling UniProtKB/TrEMBL
  Hedgehog_signalling_dom UniProtKB/TrEMBL
  Hint_dom_N UniProtKB/TrEMBL
  Hint_dom_sf UniProtKB/TrEMBL
  Intein_N UniProtKB/TrEMBL
NCBI Gene SHH ENTREZGENE
PANTHER HEDGEHOG UniProtKB/TrEMBL
  SONIC HEDGEHOG PROTEIN UniProtKB/TrEMBL
Pfam HH_signal UniProtKB/TrEMBL
  Hint UniProtKB/TrEMBL
PRINTS SONICHHOG UniProtKB/TrEMBL
PROSITE INTEIN_N_TER UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
SMART HintN UniProtKB/TrEMBL
Superfamily-SCOP SSF51294 UniProtKB/TrEMBL
  SSF55166 UniProtKB/TrEMBL
UniProt A0A2R9ATB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AZM6_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-29 SHH  sonic hedgehog signaling molecule    sonic hedgehog  Symbol and/or name change 5135510 APPROVED