RHBDD1 (rhomboid domain containing 1) - Rat Genome Database

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Gene: RHBDD1 (rhomboid domain containing 1) Pan paniscus
Analyze
Symbol: RHBDD1
Name: rhomboid domain containing 1
RGD ID: 11911370
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); INVOLVED IN membrane protein proteolysis (ortholog); positive regulation of protein catabolic process (ortholog); positive regulation of secretion (ortholog); ASSOCIATED WITH genetic disease (ortholog); pancreatic cancer (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum quality control compartment (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rhomboid-related protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213129,456,976 - 129,621,031 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B129,472,216 - 129,634,861 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B114,041,381 - 114,245,220 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B232,895,653 - 233,057,578 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B232,897,487 - 233,057,578 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RHBDD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213129,456,976 - 129,621,031 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B129,472,216 - 129,634,861 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B114,041,381 - 114,245,220 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B232,895,653 - 233,057,578 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B232,897,487 - 233,057,578 (+)Ensemblpanpan1.1panPan2
RHBDD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382226,800,159 - 226,999,210 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2226,835,581 - 226,999,215 (+)EnsemblGRCh38hg38GRCh38
GRCh372227,664,875 - 227,863,926 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,409,017 - 227,569,836 (+)NCBINCBI36Build 36hg18NCBI36
Celera2221,470,201 - 221,633,451 (+)NCBICelera
Cytogenetic Map2q36.3NCBI
HuRef2219,544,272 - 219,707,358 (+)NCBIHuRef
CHM1_12227,706,529 - 227,869,795 (+)NCBICHM1_1
T2T-CHM13v2.02227,283,017 - 227,481,905 (+)NCBIT2T-CHM13v2.0
Rhbdd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39182,294,178 - 82,423,087 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl182,294,173 - 82,423,087 (+)EnsemblGRCm39 Ensembl
GRCm38182,316,457 - 82,445,366 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl182,316,452 - 82,445,366 (+)EnsemblGRCm38mm10GRCm38
MGSCv37182,313,154 - 82,441,941 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36182,219,343 - 82,324,390 (+)NCBIMGSCv36mm8
Celera182,385,093 - 82,514,031 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map142.08NCBI
Rhbdd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8991,076,786 - 91,196,719 (+)NCBIGRCr8
mRatBN7.2983,630,037 - 83,748,690 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl983,630,063 - 83,748,689 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx992,083,454 - 92,176,482 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0997,211,935 - 97,304,967 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0995,594,879 - 95,687,904 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0988,110,731 - 88,229,462 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl988,110,731 - 88,229,479 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0987,859,493 - 87,978,041 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4981,685,464 - 81,778,714 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1981,868,882 - 81,962,132 (+)NCBI
Celera981,097,666 - 81,190,159 (+)NCBICelera
Cytogenetic Map9q34NCBI
Rhbdd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554537,528,916 - 7,644,477 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554537,527,090 - 7,656,689 (-)NCBIChiLan1.0ChiLan1.0
RHBDD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12539,719,474 - 39,844,634 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2539,719,872 - 39,842,289 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2540,337,654 - 40,462,607 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02539,967,748 - 40,092,733 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2539,967,854 - 40,092,723 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12539,904,272 - 40,029,226 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02539,739,172 - 39,864,134 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02539,918,066 - 40,043,073 (+)NCBIUU_Cfam_GSD_1.0
Rhbdd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303181,910,526 - 182,032,873 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365258,906,631 - 9,004,372 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365258,906,848 - 9,028,792 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RHBDD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15128,346,373 - 128,469,213 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115128,346,315 - 128,499,151 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215142,019,675 - 142,047,210 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RHBDD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110112,882,789 - 113,018,889 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10112,882,789 - 113,020,732 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604086,426,704 - 86,590,968 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rhbdd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248431,219,808 - 1,360,135 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248431,217,655 - 1,362,406 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000064835   ⟹   ENSPPAP00000041907
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B232,897,487 - 233,057,578 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000064836   ⟹   ENSPPAP00000041908
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B232,966,507 - 233,046,617 (+)Ensembl
RefSeq Acc Id: XM_003821827   ⟹   XP_003821875
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213129,456,979 - 129,621,031 (+)NCBI
NHGRI_mPanPan12B129,472,216 - 129,634,861 (+)NCBI
Mhudiblu_PPA_v02B114,083,293 - 114,245,220 (+)NCBI
PanPan1.12B232,895,653 - 233,057,578 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008975276   ⟹   XP_008973524
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213129,456,979 - 129,621,031 (+)NCBI
NHGRI_mPanPan12B129,474,380 - 129,634,861 (+)NCBI
Mhudiblu_PPA_v02B114,084,987 - 114,245,220 (+)NCBI
PanPan1.12B232,897,487 - 233,057,578 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008975277   ⟹   XP_008973525
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213129,456,979 - 129,621,031 (+)NCBI
NHGRI_mPanPan12B129,472,366 - 129,634,861 (+)NCBI
Mhudiblu_PPA_v02B114,083,388 - 114,245,220 (+)NCBI
PanPan1.12B232,895,865 - 233,057,578 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034955301   ⟹   XP_034811192
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213129,456,979 - 129,621,031 (+)NCBI
NHGRI_mPanPan12B129,472,413 - 129,634,861 (+)NCBI
Mhudiblu_PPA_v02B114,085,050 - 114,245,220 (+)NCBI
RefSeq Acc Id: XM_055109153   ⟹   XP_054965128
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213129,456,979 - 129,621,031 (+)NCBI
NHGRI_mPanPan12B129,474,386 - 129,634,861 (+)NCBI
RefSeq Acc Id: XM_055109154   ⟹   XP_054965129
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213129,456,976 - 129,621,031 (+)NCBI
NHGRI_mPanPan12B129,472,279 - 129,634,861 (+)NCBI
RefSeq Acc Id: XM_063595295   ⟹   XP_063451365
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213129,456,976 - 129,621,031 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003821875   ⟸   XM_003821827
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CS20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008973525   ⟸   XM_008975277
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CS20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008973524   ⟸   XM_008975276
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CS20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034811192   ⟸   XM_034955301
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CS20 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000041907   ⟸   ENSPPAT00000064835
RefSeq Acc Id: ENSPPAP00000041908   ⟸   ENSPPAT00000064836
RefSeq Acc Id: XP_054965129   ⟸   XM_055109154
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054965128   ⟸   XM_055109153
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CS20 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063451365   ⟸   XM_063595295
- Peptide Label: isoform X2
Protein Domains
Peptidase S54 rhomboid


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043550 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064835.1 UniProtKB/TrEMBL
  ENSPPAT00000064836.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1540.10 UniProtKB/TrEMBL
InterPro Peptidase_S54_rhomboid_dom UniProtKB/TrEMBL
  Rhomboid-like_sf UniProtKB/TrEMBL
KEGG Report pps:100971930 UniProtKB/TrEMBL
NCBI Gene RHBDD1 ENTREZGENE
PANTHER RHOMBOID-RELATED PROTEIN UniProtKB/TrEMBL
  RHOMBOID-RELATED PROTEIN 4 UniProtKB/TrEMBL
Pfam Rhomboid UniProtKB/TrEMBL
Superfamily-SCOP SSF144091 UniProtKB/TrEMBL
UniProt A0A2R9CLM6_PANPA UniProtKB/TrEMBL
  A0A2R9CS20 ENTREZGENE, UniProtKB/TrEMBL