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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bromuconazole
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Accession:CHEBI:81900 term browser browse the term
Definition:A member of the class of oxolanes carrying 1,2,4-triazol-ylmethyl and 2,4-dichlorophenyl substituents at position 2 as well as a bromo substituent at position 4. A foliar applied conazole fungicide for a range of crops including cereals, fruit, vegetables and vines.
Synonyms:exact_synonym: 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol
 related_synonym: 1-((4-Bromo-2-(2,4-dichlorophenyl)tetrahydro-2-furanyl)methyl)-1H-1,2,4-triazole;   Formula=C13H12BrCl2N3O;   InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2;   InChIKey=HJJVPARKXDDIQD-UHFFFAOYSA-N;   SMILES=N1(N=CN=C1)CC2(CC(CO2)Br)C=3C(=CC(=CC3)Cl)Cl
 xref: AGR:IND43838427;   CAS:116255-48-2;   KEGG:C18704
 xref_mesh: MESH:C573694
 xref: PMID:17573638;   PMID:19517438;   PMID:22532344;   PMID:23616354;   PPDB:97;   Patent:EP258161;   Pesticides:bromuconazole;   Reaxys:8393967


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bromuconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP bromuconazole results in decreased expression of ABCC2 mRNA CTD PMID:33789219 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Ar androgen receptor multiple interactions ISO bromuconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP bromuconazole results in increased expression of BAX mRNA CTD PMID:36370923 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP bromuconazole results in decreased expression of BCL2 mRNA CTD PMID:36370923 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity EXP bromuconazole results in increased activity of CASP3 mRNA CTD PMID:36370923 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cldn1 claudin 1 affects expression EXP bromuconazole affects the expression of CLDN1 mRNA CTD PMID:33789219 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression EXP bromuconazole results in decreased expression of CROT mRNA CTD PMID:33789219 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP bromuconazole results in increased expression of CYP1A2 mRNA CTD PMID:33789219 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression EXP bromuconazole results in increased expression of CYP27A1 mRNA CTD PMID:33789219 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression
increases expression		 EXP bromuconazole results in decreased expression of CYP2B1
bromuconazole results in increased expression of CYP2B1 mRNA		 CTD PMID:28532222 PMID:33789219 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP bromuconazole results in increased expression of CYP2B2 mRNA CTD PMID:33789219 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP bromuconazole results in increased expression of CYP2C11 mRNA CTD PMID:33789219 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases expression EXP bromuconazole results in increased expression of CYP2C6 mRNA CTD PMID:33789219 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP bromuconazole results in increased expression of CYP3A23-3A1 CTD PMID:28532222 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression EXP bromuconazole results in increased expression of CYP3A9 mRNA CTD PMID:33789219 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression EXP bromuconazole results in decreased expression of CYP8B1 mRNA CTD PMID:33789219 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO bromuconazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression EXP bromuconazole results in decreased expression of FABP7 mRNA CTD PMID:33789219 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880 		JBrowse link
G Fam13a family with sequence similarity 13, member A affects expression EXP bromuconazole affects the expression of FAM13A mRNA CTD PMID:33789219 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860 		JBrowse link
G Gckr glucokinase regulator decreases expression EXP bromuconazole results in decreased expression of GCKR mRNA CTD PMID:33789219 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654 		JBrowse link
G Gfra3 GDNF family receptor alpha 3 increases expression EXP bromuconazole results in increased expression of GFRA3 mRNA CTD PMID:33789219 NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression EXP bromuconazole results in increased expression of GOT1 protein CTD PMID:33789219 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP bromuconazole results in increased expression of GPAM mRNA CTD PMID:33789219 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gpr39 G protein-coupled receptor 39 increases expression EXP bromuconazole results in increased expression of GPR39 mRNA CTD PMID:33789219 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267 		JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression EXP bromuconazole results in increased expression of HACL1 mRNA CTD PMID:33789219 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027 		JBrowse link
G Hnf1a HNF1 homeobox A increases expression EXP bromuconazole results in increased expression of HNF1A mRNA CTD PMID:33789219 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP bromuconazole results in increased expression of HPRT1 mRNA CTD PMID:33789219 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP bromuconazole results in decreased expression of HSD17B2 mRNA CTD PMID:33789219 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression EXP bromuconazole results in decreased expression of HSP90AA1 mRNA CTD PMID:33789219 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Ier5 immediate early response 5 increases expression EXP bromuconazole results in increased expression of IER5 mRNA CTD PMID:33789219 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression EXP bromuconazole results in decreased expression of IFIT3 mRNA CTD PMID:33789219 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Insig1 insulin induced gene 1 increases expression EXP bromuconazole results in increased expression of INSIG1 mRNA CTD PMID:33789219 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 increases expression EXP bromuconazole results in increased expression of INSIG2 mRNA CTD PMID:33789219 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression EXP bromuconazole results in decreased expression of ISG15 mRNA CTD PMID:33789219 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Jade1 jade family PHD finger 1 decreases expression EXP bromuconazole results in decreased expression of JADE1 mRNA CTD PMID:33789219 NCBI chr 2:124,543,233...124,596,361
Ensembl chr 2:124,543,286...124,596,354 		JBrowse link
G Kalrn kalirin, RhoGEF kinase increases expression EXP bromuconazole results in increased expression of KALRN mRNA CTD PMID:33789219 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610 		JBrowse link
G Kynu kynureninase decreases expression EXP bromuconazole results in decreased expression of KYNU mRNA CTD PMID:33789219 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Lgalsl galectin-like affects expression EXP bromuconazole affects the expression of LGALSL mRNA CTD PMID:33789219 NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980 		JBrowse link
G Lpl lipoprotein lipase decreases expression EXP bromuconazole results in decreased expression of LPL mRNA CTD PMID:33789219 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Manea mannosidase, endo-alpha affects expression EXP bromuconazole affects the expression of MANEA mRNA CTD PMID:33789219 NCBI chr 5:40,196,373...40,218,540
Ensembl chr 5:40,196,396...40,218,459 		JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression EXP bromuconazole results in decreased expression of MX2 mRNA CTD PMID:33789219 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression EXP bromuconazole results in increased expression of NFIL3 mRNA CTD PMID:33789219 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression EXP bromuconazole results in increased expression of NR0B2 mRNA CTD PMID:33789219 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression EXP bromuconazole results in decreased expression of NR1D1 mRNA CTD PMID:33789219 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 decreases expression EXP bromuconazole results in decreased expression of NR1D2 mRNA CTD PMID:33789219 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression EXP bromuconazole results in increased expression of NR1H4 mRNA CTD PMID:33789219 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
multiple interactions		 EXP
ISO		 bromuconazole results in increased expression of NR1I2
bromuconazole binds to and results in increased activity of NR1I2 protein		 CTD PMID:28532222 PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression EXP bromuconazole results in decreased expression of NR1I3 CTD PMID:28532222 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Pex5 peroxisomal biogenesis factor 5 increases expression EXP bromuconazole results in increased expression of PEX5 mRNA CTD PMID:33789219 NCBI chr 4:157,270,671...157,296,432
Ensembl chr 4:157,270,672...157,296,431 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression		 ISO
EXP		 bromuconazole binds to and results in increased activity of PPARG protein
bromuconazole results in decreased expression of PPARG protein		 CTD PMID:33049310 PMID:33789219 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha increases expression EXP bromuconazole results in increased expression of PRKAR2A mRNA CTD PMID:33789219 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Rn7sl1 RNA component of signal recognition particle 7SL1 decreases expression EXP bromuconazole results in decreased expression of RN7SL1 mRNA CTD PMID:33789219 NCBI chr 6:87,636,808...87,637,106
Ensembl chr 6:87,636,804...87,637,103 		JBrowse link
G Rorc RAR-related orphan receptor C increases expression EXP bromuconazole results in increased expression of RORC mRNA CTD PMID:33789219 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907 		JBrowse link
G Sesn2 sestrin 2 increases expression EXP bromuconazole results in increased expression of SESN2 mRNA CTD PMID:33789219 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Slc28a2 solute carrier family 28 member 2 decreases expression EXP bromuconazole results in decreased expression of SLC28A2 mRNA CTD PMID:33789219 NCBI chr 3:109,324,815...109,387,702
Ensembl chr 3:109,366,996...109,387,702 		JBrowse link
G Slfn4 schlafen family member 4 decreases expression EXP bromuconazole results in decreased expression of SLFN4 mRNA CTD PMID:33789219 NCBI chr10:67,994,601...68,018,141
Ensembl chr10:68,000,028...68,018,138
Ensembl chr10:68,000,028...68,018,138 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP bromuconazole results in increased expression of TP53 mRNA CTD PMID:36370923 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP bromuconazole results in increased expression of UGT2B1 mRNA CTD PMID:33789219 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases expression EXP bromuconazole results in increased expression of UGT2B7 mRNA CTD PMID:33789219 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
G Wdr6 WD repeat domain 6 increases expression EXP bromuconazole results in increased expression of WDR6 mRNA CTD PMID:33789219 NCBI chr 8:109,268,079...109,274,504
Ensembl chr 8:109,268,079...109,274,499 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      application 19703
        pesticide 18059
          antifungal agrochemical 12051
            bromuconazole 60
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            organic molecule 19714
                              organic cyclic compound 19485
                                organic heterocyclic compound 18881
                                  heteroarene 17148
                                    monocyclic heteroarene 14977
                                      azole 14500
                                        triazoles 8421
                                          triazole antifungal agent 5748
                                            triazole fungicide 5723
                                              bromuconazole 60
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