Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ribavirin
go back to main search page
Accession:CHEBI:63580 term browser browse the term
Definition:A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses.
Synonyms:related_synonym: 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide;   1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide;   Formula=C8H12N4O5;   InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1;   InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N;   RBV;   SMILES=NC(=O)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O;   ribavirina;   ribavirine;   ribavirinum
 alt_id: CHEBI:8840
 xref: CAS:36791-04-5;   DrugBank:DB00811;   Drug_Central:2373;   KEGG:D00423;   LINCS:LSM-5701
 xref_mesh: MESH:D012254
 xref: PMID:21827730;   PMID:22052088;   PMID:22052220;   PMID:22156853;   PMID:22158703;   PMID:22212566;   PMID:22212568;   PMID:22212569;   PMID:22212572;   PMID:22212576;   PMID:22212579;   PMID:22220723;   PMID:22239498;   PMID:22239511;   PMID:29438107;   Reaxys:892462;   Wikipedia:Ribavirin


show annotations for term's descendants           Sort by:
ribavirin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 decreases expression ISO Ribavirin results in decreased expression of ACTN2 protein CTD PMID:32112805 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Ribavirin results in decreased phosphorylation of AKT1 protein CTD PMID:29112301 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 multiple interactions
decreases expression		 ISO Ribavirin inhibits the reaction [CARM1 protein binds to EIF4E promoter]; Ribavirin inhibits the reaction [CARM1 protein binds to VEGFA promoter]
Ribavirin results in decreased expression of CARM1 protein		 CTD PMID:34919946 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO Ribavirin results in increased activity of CASP3 protein
Ribavirin promotes the reaction [FAS protein results in increased activity of CASP3 protein]		 CTD PMID:12760867 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO Ribavirin promotes the reaction [FAS protein results in increased activity of CASP7 protein] CTD PMID:12760867 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO Ribavirin promotes the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:12760867 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Ribavirin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein] CTD PMID:36416909 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Ribavirin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] CTD PMID:36416909 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Ribavirin results in decreased expression of CCNA2 protein CTD PMID:33577917 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Ribavirin results in decreased expression of CCND1 protein CTD PMID:29112301 PMID:33577917 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Ribavirin results in decreased expression of CCNE1 protein CTD PMID:33577917 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions
decreases phosphorylation
decreases expression		 ISO Ribavirin inhibits the reaction [CARM1 protein binds to EIF4E promoter]; Ribavirin inhibits the reaction [Doxorubicin results in increased phosphorylation of EIF4E protein]
Ribavirin results in decreased phosphorylation of EIF4E protein
Ribavirin results in decreased expression of EIF4E mRNA; Ribavirin results in decreased expression of EIF4E protein		 CTD PMID:29112301 PMID:33577917 PMID:34919946 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation ISO Ribavirin results in decreased phosphorylation of EIF4EBP1 protein CTD PMID:29112301 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Epo erythropoietin multiple interactions
increases expression		 ISO [peginterferon alfa-2b co-treated with Ribavirin] affects the expression of EPO protein; [Ribavirin co-treated with Interferons] results in increased expression of EPO protein
Ribavirin results in increased expression of EPO		 CTD PMID:12713065 PMID:15232364 PMID:20009130 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Ribavirin promotes the reaction [FAS protein results in increased activity of CASP3 protein]; Ribavirin promotes the reaction [FAS protein results in increased activity of CASP7 protein]; Ribavirin promotes the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:12760867 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Gas5 growth arrest specific 5 increases expression ISO Ribavirin results in increased expression of GAS5 mRNA CTD PMID:32112805 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gata4 GATA binding protein 4 decreases expression ISO Ribavirin results in decreased expression of GATA4 mRNA CTD PMID:32112805 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO Ribavirin results in increased expression of H2AX protein modified form CTD PMID:32112805 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO Ribavirin results in decreased expression of ICAM1 protein modified form CTD PMID:12853993 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
increases expression		 ISO [Ribavirin co-treated with IFNA2 protein] affects the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Ribavirin inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]; Ribavirin results in increased expression of and results in increased secretion of IFNG protein
Ribavirin results in decreased expression of IFNG mRNA
Ribavirin results in increased expression of IFNG mRNA; Ribavirin results in increased expression of IFNG protein		 CTD PMID:9722937 PMID:10190717 PMID:10770762 PMID:17210188 PMID:29594315 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifnl3 interferon, lambda 3 multiple interactions ISO IFNL3 gene polymorphism affects the susceptibility to [Ribavirin co-treated with IFNA2 protein modified form]; IFNL3 gene SNP affects the susceptibility to [peginterferon alfa-2a co-treated with Ribavirin]; IFNL3 protein results in increased susceptibility to [Ribavirin co-treated with IFNA2 protein modified form] CTD PMID:19749757 PMID:19749758 PMID:22003405 NCBI chr 1:83,814,456...83,816,096
Ensembl chr 1:83,814,564...83,816,096 		JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression		 ISO
EXP		 [Ribavirin co-treated with IFNA2 protein] affects the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; Ribavirin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; Ribavirin results in decreased expression of and results in decreased secretion of IL10 protein
Ribavirin results in decreased expression of IL10 mRNA
Ribavirin results in decreased expression of IL10 protein
[peginterferon alfa-2a co-treated with Ribavirin co-treated with Danazol] results in decreased expression of IL10 mRNA; [peginterferon alfa-2a co-treated with Ribavirin] results in increased expression of IL10 mRNA		 CTD PMID:9722937 PMID:10190717 PMID:10770762 PMID:17210188 PMID:18007553 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO [Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]; Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:9722937 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO [Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]; Ribavirin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]; Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:9722937 PMID:36416909 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO Ribavirin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
Ribavirin results in increased expression of IL1B mRNA		 CTD PMID:9722937 PMID:29594315 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression		 ISO [Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of IL2 protein]; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of IL2 protein]; Ribavirin results in increased expression of and results in increased secretion of IL2 protein
Ribavirin results in increased expression of IL2 protein
Ribavirin results in increased expression of IL2 mRNA; Ribavirin results in increased expression of IL2 protein		 CTD PMID:9722937 PMID:10190717 PMID:10770762 PMID:29594315 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions		 ISO Ribavirin results in decreased expression of IL4 mRNA; Ribavirin results in decreased expression of IL4 protein
Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of IL4 protein]; Ribavirin results in decreased expression of and results in decreased secretion of IL4 protein		 CTD PMID:9722937 PMID:10190717 PMID:10770762 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 decreases expression
multiple interactions		 ISO Ribavirin results in decreased expression of IL5 mRNA; Ribavirin results in decreased expression of IL5 protein
Ribavirin results in decreased expression of and results in decreased secretion of IL5 protein		 CTD PMID:10190717 PMID:10770762 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP [peginterferon alfa-2a co-treated with Ribavirin co-treated with Danazol] results in decreased expression of IL6 mRNA CTD PMID:18007553 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Isl1 ISL LIM homeobox 1 decreases expression ISO Ribavirin results in decreased expression of ISL1 mRNA CTD PMID:32112805 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Itpa inosine triphosphatase increases response to substance ISO ITPA 5' UTR SNP results in increased susceptibility to Ribavirin CTD PMID:20637204 NCBI chr 3:117,885,464...117,897,247
Ensembl chr 3:117,885,099...117,897,249 		JBrowse link
G Klrc1 killer cell lectin like receptor C1 affects expression ISO Ribavirin co-treated with Interferon alfa-2a affects expression of KLRC1 protein in Natural Killer cells RGD PMID:20550548 RGD:40818079 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO Ribavirin results in decreased phosphorylation of MTOR protein CTD PMID:29112301 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Ribavirin results in decreased expression of MYC protein CTD PMID:29112301 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myh6 myosin heavy chain 6 decreases expression ISO Ribavirin results in decreased expression of MYH6 mRNA CTD PMID:32112805 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A multiple interactions ISO [Ribavirin co-treated with IFNA2 protein] results in increased activity of OAS1 protein CTD PMID:9722937 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Ribavirin results in decreased expression of PCNA protein CTD PMID:33577917 PMID:34919946 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 affects expression ISO Ribavirin affects the expression of PRMT1 protein CTD PMID:34919946 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Prmt2 protein arginine methyltransferase 2 decreases expression ISO Ribavirin results in decreased expression of PRMT2 protein CTD PMID:34919946 NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643 		JBrowse link
G Prmt3 protein arginine methyltransferase 3 decreases expression ISO Ribavirin results in decreased expression of PRMT3 protein CTD PMID:34919946 NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435 		JBrowse link
G Prmt5 protein arginine methyltransferase 5 decreases expression ISO Ribavirin results in decreased expression of PRMT5 protein CTD PMID:33577917 PMID:34919946 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296 		JBrowse link
G Prmt6 protein arginine methyltransferase 6 affects expression ISO Ribavirin affects the expression of PRMT6 protein CTD PMID:34919946 NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648 		JBrowse link
G Prmt7 protein arginine methyltransferase 7 decreases expression ISO Ribavirin results in decreased expression of PRMT7 protein CTD PMID:33577917 PMID:34919946 NCBI chr19:34,110,724...34,161,531
Ensembl chr19:34,110,747...34,162,577 		JBrowse link
G Prmt8 protein arginine methyltransferase 8 decreases expression ISO Ribavirin results in decreased expression of PRMT8 protein CTD PMID:34919946 NCBI chr 4:160,535,813...160,618,193
Ensembl chr 4:160,535,813...160,617,930 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases uptake ISO SLC29A1 protein results in increased uptake of Ribavirin CTD PMID:20185188 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Ribavirin CTD PMID:19164483 NCBI chr20:28,645,265...28,685,388
Ensembl chr20:28,647,391...28,685,388 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases expression		 ISO Ribavirin promotes the reaction [SLC6A4 protein results in increased uptake of Serotonin]; Ribavirin results in increased expression of and results in increased activity of SLC6A4 protein
Ribavirin results in increased expression of SLC6A4 mRNA		 CTD PMID:16476009 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO
EXP		 Ribavirin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Ribavirin results in increased expression of and results in increased secretion of TNF protein
Ribavirin results in increased expression of TNF mRNA; Ribavirin results in increased expression of TNF protein
[peginterferon alfa-2a co-treated with Ribavirin co-treated with Danazol] results in decreased expression of TNF mRNA		 CTD PMID:9722937 PMID:10190717 PMID:10770762 PMID:18007553 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases response to substance ISO Ribavirin results in decreased susceptibility to TNFSF10 protein CTD PMID:12637521 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO Ribavirin results in decreased expression of TNNT2 protein CTD PMID:32112805 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity		 ISO Ribavirin results in increased expression of TP53 protein
Ribavirin results in increased expression of TRP53 protein
Ribavirin affects the activity of TP53 protein		 CTD PMID:32112805 PMID:33577917 PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO Ribavirin results in decreased expression of TXN protein CTD PMID:16198661 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions
decreases secretion		 ISO Ribavirin results in decreased expression of VEGFA mRNA; Ribavirin results in decreased expression of VEGFA protein
Ribavirin inhibits the reaction [CARM1 protein binds to VEGFA promoter]
Ribavirin results in decreased secretion of VEGFA protein		 CTD PMID:29112301 PMID:34919946 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      biological role 19858
        antimicrobial agent 18239
          antiviral agent 11339
            ribavirin 53
              ribavirin 5'-diphosphate 0
              ribavirin 5'-monophosphate 0
              ribavirin 5'-triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            heteroorganic entity 19502
                              organochalcogen compound 19264
                                organooxygen compound 19180
                                  carbon oxoacid 18666
                                    carboxylic acid 18663
                                      carboacyl group 17715
                                        univalent carboacyl group 17690
                                          carbamoyl group 17566
                                            carboxamide 17566
                                              primary carboxamide 6006
                                                1,2,4-triazole-3-carboxamide 53
                                                  ribavirin 53
                                                    ribavirin 5'-diphosphate 0
                                                    ribavirin 5'-monophosphate 0
                                                    ribavirin 5'-triphosphate 0
paths to the root