| 628678 | F7 | coagulation factor VII | ENCODES a protein that exhibits endopeptidase activity; signaling receptor binding; serine-type endopeptidase activity (ortholog); INVOLVED IN animal organ regeneration; circadian rhythm; positive regulation of blood coagulation; PARTICIPATES IN coagulation cascade pathway; acenocoumarol pharmacodyn amics pathway; alteplase pharmacodynamics pathway; ASSOCIATED WITH Arterial Thrombosis; asthma; bilirubin metabolic disorder; FOUND IN extracellular space; vesicle; membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; acenocoumarol | 16 | 83191896 | 83202775 | Rat | 303 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1307828 | Irf7 | interferon regulatory factor 7 | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cytoplasmic pattern recognition receptor signaling pathway (ortholog); defense respons e to virus (ortholog); immunoglobulin mediated immune response (ortholog); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; ASSOCIATED WITH COVID-19 (ortholog); Human Influenza (ortholog); immunodeficiency 39 (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol | 1 | 205796956 | 205800543 | Rat | 333 | symbol , PhenoGen , UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1566170 | Nxf7 | nuclear RNA export factor 7 | ENCODES a protein that exhibits mRNA binding (ortholog); RNA binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); RNA transport (ortholog); PARTICIPATES IN influenza A pathway; mRNA decay pathway; ribosome biogenesis pathway; ASSOCIATED WITH focal segmental glomerulosclerosis (orthol og); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; fenvalerate; trichloroethene | X | 102828592 | 102845799 | Rat | 49 | symbol , PhenoGen , UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1305140 | Dcaf7 | DDB1 and CUL4 associated factor 7 | ASSOCIATED WITH Craniofacial Abnormalities (ortholog); myeloid leukemia associated with Down Syndrome (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (ortholog); cytosol (ortholog); nuclear matrix (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2 -thiouracil | 10 | 91473900 | 91496080 | Rat | 80 | symbol , PhenoGen , UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1559653 | Traf7 | TNF receptor associated factor 7 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN positive regulation of neuron apoptotic process; apoptotic process (ortholog); cellular response to interleukin-6 (ortholog); ASSOCIATED WITH Spinal Cord Injur ies; adenomatoid tumor (ortholog); Cardiac, Facial, and Digital Anomalies with Developmental Delay (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; ammonium chloride | 10 | 14038117 | 14056832 | Rat | 94 | symbol , PhenoGen , UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1306244 | Rassf7 | Ras association domain family member 7 | INVOLVED IN apoptotic process (inferred); signal transduction (inferred); FOUND IN centriolar satellite (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 205749173 | 205753350 | Rat | 76 | symbol , UniProt , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1583744 | Atf7ip2 | activating transcription factor 7 interacting protein 2 | INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin | 10 | 5909898 | 5952844 | Rat | 49 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1563941 | C8h11orf71 | similar to human chromosome 11 open reading frame 71 | INTERACTS WITH (+)-schisandrin B; acetamide; acrylamide | 8 | 57735075 | 57735489 | Rat | 40 | symbol , UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305810 | Tspan4 | tetraspanin 4 | ENCODES a protein that exhibits antigen binding (ortholog); integrin binding (ortholog); INVOLVED IN mitocytosis (ortholog); protein-containing complex assembly (ortholog); regulation of mitochondrial membrane potential (ortholog); FOUND IN migrasome (ortholog); plasma membrane (ortholog); vesicle ( ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 3-chloropropane-1,2-diol | 1 | 206001731 | 206021414 | Rat | 140 | UniProt , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1562665 | Zfp707l1 | zinc finger protein 707-like 1 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); sequence-specific double-stranded DNA binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH parace tamol | 7 | 109531227 | 109542044 | Rat | 8 | UniProt , old_protein_id , UniProt Secondary , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1560499 | Cd27 | CD27 molecule | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN response to ethanol; adaptive immune memory response involving T cells and B cells (ortholog); CD27 signaling pat hway (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH alcohol-associated liver disease; Cachexia (ortholog); Chediak-Higashi syndrome (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol | 4 | 159716932 | 159721823 | Rat | 123 | UniProt , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306195 | 1700009N14Rikl | RIKEN cDNA 1700009N14 gene like | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN nucleocytoplasmic transport (inferred); protein transport (inferred); PARTICIPATES IN ribosome biogenesis pathway; RNA transport pathway; FOUND IN nuclear envelope (inferred ); nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; C60 fullerene | 5 | 59252092 | 59253468 | Rat | 22 | UniProt | gene, protein-coding, PREDICTED [RefSeq] |
| 15004016 | AABR07004891.1 | | | | | | Rat | | UniProt Secondary | gene, protein-coding |
| 15003423 | AABR07005588.1 | | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN tRNA modification (inferred) | | | | Rat | 5 | old_protein_id | gene, protein-coding |
| 15003900 | AABR07006688.2 | | ENCODES a protein that exhibits translation elongation factor activity (inferred); INVOLVED IN translation (inferred); translational elongation (inferred); FOUND IN eukaryotic translation elongation factor 1 complex (inferred) | | | | Rat | 9 | UniProt | gene, protein-coding |
| 15005795 | AABR07018556.1 | | ENCODES a protein that exhibits nucleotide binding (inferred); INVOLVED IN retrotransposition (inferred); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); nucleolus (inferred) | | | | Rat | 8 | UniProt | gene, protein-coding |
| 15003999 | AABR07025089.1 | | FOUND IN nucleoplasm (inferred) | | | | Rat | 16 | UniProt | gene, protein-coding |
| 15003762 | AABR07030544.1 | | | | | | Rat | | UniProt | gene, protein-coding |
| 15004296 | AABR07038477.1 | | | | | | Rat | | old_protein_id , UniProt Secondary | gene, protein-coding |
| 15004259 | AABR07039936.1 | | ENCODES a protein that exhibits vitamin-K-epoxide reductase (warfarin-sensitive) activity (inferred); INVOLVED IN vitamin K metabolic process (inferred) | | | | Rat | 4 | old_protein_id , UniProt Secondary | gene, protein-coding |
| 15004026 | AABR07048271.1 | | | | | | Rat | | UniProt | gene, protein-coding |
| 15003293 | AABR07062238.1 | | FOUND IN extracellular region (inferred) | | | | Rat | 1 | old_protein_id | gene, protein-coding |
| 1311066 | Aar2 | AAR2 splicing factor | INVOLVED IN mRNA processing (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Developmental Disabilities (ortholog); FOUND IN spliceosomal complex (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 3 | 165517467 | 165540260 | Rat | 44 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311794 | Abi3 | ABI family, member 3 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN modification of postsynaptic actin cytoskeleton; defense response to tumor cell (ortholog); negative regulation of lamellipodium assembly (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); hereditary breast ov arian cancer syndrome (ortholog); FOUND IN glutamatergic synapse; postsynapse; cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 81266571 | 81277561 | Rat | 114 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309314 | Accs | 1-aminocyclopropane-1-carboxylate synthase | ENCODES a protein that exhibits 1-aminocyclopropane-1-carboxylate synthase activity (ortholog); identical protein binding (ortholog); ASSOCIATED WITH COVID-19 (ortholog); INTERACTS WITH atrazine; bisphenol A; gentamycin | 3 | 100261940 | 100276400 | Rat | 46 | UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1359188 | Acot9 | acyl-CoA thioesterase 9 | ENCODES a protein that exhibits acetyl-CoA hydrolase activity (ortholog); fatty acyl-CoA hydrolase activity (ortholog); long-chain fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN acyl-CoA metabolic process (ortholog); long-chain fatty acid metabolic process (ortholog); short-chain fatty ac id metabolic process (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene | X | 43922943 | 43973311 | Rat | 128 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306515 | Actr10 | actin related protein 10 | INVOLVED IN microtubule-based movement (ortholog); microtubule-based process (ortholog); PARTICIPATES IN mitochondria transport pathway; FOUND IN dynactin complex (ortholog); INTERACTS WITH 2,6-dinitrotoluene; benzo[a]pyrene; bisphenol A | 6 | 95182082 | 95208325 | Rat | 70 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307380 | Actr1b | actin related protein 1B | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN cytoskeleton organization (inferred); ASSOCIATED WITH Duane retraction syndrome (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; atrazin e | 9 | 46424677 | 46434341 | Rat | 67 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304609 | Actr6 | actin related protein 6 | INVOLVED IN nucleolus organization (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nucleolus (ortholog); Swr1 complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 26037574 | 26058362 | Rat | 70 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309068 | Adprs | ADP-ribosylserine hydrolase | ENCODES a protein that exhibits ADP-ribosylserine hydrolase activity (ortholog); hydrolase activity, hydrolyzing O-glycosyl compounds (ortholog); magnesium ion binding (ortholog); INVOLVED IN cellular response to superoxide (ortholog); DNA repair (ortholog); negative regulation of necroptotic proces s (ortholog); ASSOCIATED WITH genetic disease (ortholog); sensorineural hearing loss (ortholog); stress-induced childhood-onset neurodegeneration with variable ataxia and seizures (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 5 | 143898542 | 143903816 | Rat | 125 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303287 | Agpat1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | ENCODES a protein that exhibits 1-acylglycerol-3-phosphate O-acyltransferase activity (ortholog); INVOLVED IN phosphatidic acid biosynthetic process (ortholog); positive regulation of cytokine production (ortholog); PARTICIPATES IN D-glycericacidemia pathway; familial lipoprotein lipase deficiency p athway; glycerol kinase deficiency pathway; ASSOCIATED WITH exfoliation syndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol | 20 | 4140565 | 4149531 | Rat | 113 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306725 | Ahsp | alpha hemoglobin stabilizing protein | ENCODES a protein that exhibits hemoglobin binding (inferred); INVOLVED IN erythrocyte differentiation (ortholog); protein folding (ortholog); protein stabilization (ortholog); ASSOCIATED WITH cerebral infarction (ortholog); coronary restenosis (ortholog); Fetal Death (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl | 1 | 192310306 | 192315943 | Rat | 70 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308277 | Akr1b10 | aldo-keto reductase family 1 member B10 | ENCODES a protein that exhibits aldose reductase (NADPH) activity; all-trans-retinol dehydrogenase (NADP+) activity; NADP+ binding; INVOLVED IN polyol metabolic process; retinal metabolic process; retinol metabolic process; PARTICIPATES IN retinol metabolic pathway; ASSOCIATED WITH autism spectrum d isorder (ortholog); Colorectal Neoplasms (ortholog); contact dermatitis (ortholog); FOUND IN cytosol (ortholog); extracellular region (ortholog); lysosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene | 4 | 64005632 | 64027860 | Rat | 338 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1561929 | Albfm1 | albumin superfamily member 1 | FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH 17beta-estradiol (ortholog); 4,4'-sulfonyldiphenol (ortholog); bisphenol F (ortholog) | 14 | 17762615 | 17814075 | Rat | 13 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308608 | Alkbh4 | alkB homolog 4, lysine demethylase | ENCODES a protein that exhibits 2-oxoglutarate-dependent dioxygenase activity (ortholog); actin binding (ortholog); broad specificity oxidative DNA demethylase activity (ortholog); INVOLVED IN actomyosin structure organization (ortholog); cleavage furrow ingression (ortholog); positive regulation of gene expression, epigenetic (ortholog); FOUND IN contractile ring (ortholog); midbody (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amitrole | 12 | 26160643 | 26166560 | Rat | 54 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308936 | Anapc10 | anaphase promoting complex subunit 10 | INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); protein branched polyubiquitination (ortholog); protein K11-linked ubiquitination (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Mayer-Rokitansky-Kuster- Hauser syndrome type 1 (ortholog); FOUND IN anaphase-promoting complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 19 | 45057278 | 45109882 | Rat | 77 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305546 | Anapc2 | anaphase promoting complex subunit 2 | INVOLVED IN negative regulation of gene expression; positive regulation of axon extension; positive regulation of dendrite morphogenesis; PARTICIPATES IN cell cycle pathway, mitotic; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); aplastic anemia (ortholo g); Fetal Growth Retardation (ortholog); FOUND IN anaphase-promoting complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 3 | 28484590 | 28496338 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359373 | Ang2 | angiogenin, ribonuclease A family, member 2 | ENCODES a protein that exhibits RNA nuclease activity (ortholog); INVOLVED IN cellular response to mechanical stimulus; angiotensin-activated signaling pathway (ortholog); cardiac muscle hypertrophy (ortholog); FOUND IN extracellular region (inferred); nucleolus (inferred); INTERACTS WITH (+)-schisa ndrin B; 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil | 15 | 26871842 | 26889421 | Rat | 45 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1564505 | Angptl3 | angiopoietin-like 3 | ENCODES a protein that exhibits enzyme inhibitor activity (ortholog); growth factor activity (ortholog); integrin binding (ortholog); INVOLVED IN response to hormone; acylglycerol homeostasis (ortholog); artery morphogenesis (ortholog); PARTICIPATES IN lipid metabolic pathway; ASSOCIATED WITH Experi mental Diabetes Mellitus (ortholog); Experimental Liver Cirrhosis (ortholog); familial hypobetalipoproteinemia 2 (ortholog); FOUND IN cell surface (ortholog); early endosome (ortholog); extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 5 | 118818494 | 118825531 | Rat | 213 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308577 | Ankrd13a | ankyrin repeat domain 13a | ENCODES a protein that exhibits ubiquitin-modified protein reader activity (ortholog); INVOLVED IN negative regulation of protein localization to endosome (ortholog); negative regulation of receptor internalization (ortholog); FOUND IN cytoplasm (ortholog); late endosome (ortholog); perinuclear regi on of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aconitine | 12 | 47458828 | 47488959 | Rat | 91 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565715 | Ankrd37 | ankyrin repeat domain 37 | FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 16 | 53001487 | 53004545 | Rat | 160 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 11508551 | Anp32a | acidic nuclear phosphoprotein 32 family member A | ENCODES a protein that exhibits cell adhesion molecule binding; integrin binding; INVOLVED IN negative regulation of plasma membrane bounded cell projection assembly; negative regulation of protein modification process; nucleocytoplasmic transport (ortholog); PARTICIPATES IN CRM1 export pathway; ASS OCIATED WITH Brain Injuries; Acute Liver Failure (ortholog); Animal Disease Models (ortholog); FOUND IN chromatin; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1-bromopropane; 17beta-estradiol | 8 | 71724578 | 71760922 | Rat | 189 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309911 | Anxa11 | annexin A11 | ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent phospholipid binding (ortholog); calcium-dependent protein binding (ortholog); INVOLVED IN cytokinetic process (ortholog); phagocytosis (ortholog); response to calcium ion (ortholog); ASSOCIATED WITH amyotrophic latera l sclerosis (ortholog); amyotrophic lateral sclerosis type 23 (ortholog); genetic disease (ortholog); FOUND IN azurophil granule (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; azoxystrobin | 16 | 1419627 | 1464590 | Rat | 152 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305911 | Ap1s1 | adaptor related protein complex 1 subunit sigma 1 | ENCODES a protein that exhibits clathrin adaptor activity (inferred); INVOLVED IN response to virus (ortholog); retrograde transport, endosome to Golgi (ortholog); ASSOCIATED WITH genetic disease (ortholog); intrahepatic cholestasis (ortholog); lipid storage disease (ortholog); FOUND IN Golgi appara tus (ortholog); presynapse (ortholog); terminal bouton (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole | 12 | 25261958 | 25272483 | Rat | 139 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1561862 | Ap1s2 | adaptor related protein complex 1 subunit sigma 2 | ENCODES a protein that exhibits clathrin adaptor activity (inferred); INVOLVED IN adipose tissue development (ortholog); fat cell differentiation (ortholog); neuromuscular process controlling balance (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); syn dromic X-linked intellectual disability 5 (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | X | 34204601 | 34230819 | Rat | 147 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308659 | Ap3d1 | adaptor related protein complex 3 subunit delta 1 | INVOLVED IN synaptic vesicle budding from endosome; anterograde axonal transport (ortholog); anterograde synaptic vesicle transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); hemorrhagic disease (ortholog); Hermansky-Pudlak syndrome (ortholog); FOUND IN axon (ortholog); endosome membran e (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil | 7 | 9620909 | 9656350 | Rat | 160 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562045 | Apcdd1l | APC down-regulated 1 like | ENCODES a protein that exhibits Wnt-protein binding (inferred); INVOLVED IN negative regulation of Wnt signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH atrazine; bisphenol A; methoxychlor | 3 | 183000504 | 183076628 | Rat | 51 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311546 | Aph1a | aph-1A gamma-secretase subunit | ENCODES a protein that exhibits endopeptidase activator activity (ortholog); enzyme binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN amyloid precursor protein catabolic process (ortholog); amyloid precursor protein metabolic process (ortholog); amyloid-beta formatio n (ortholog); PARTICIPATES IN Notch signaling pathway; syndecan signaling pathway; Alzheimer's disease pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN early endosome; presynaptic membrane; synaptic membrane; INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; bisphenol A | 2 | 186123023 | 186130886 | Rat | 101 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309772 | Api5 | apoptosis inhibitor 5 | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); INVOLVED IN apoptotic process (inferred); negative regulation of apoptotic process (inferred); ASSOCIATED WITH cervical cancer (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); spliceosomal complex (inferre d); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 3 | 100833417 | 100858580 | Rat | 38 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308727 | Apobec2 | apolipoprotein B mRNA editing enzyme catalytic subunit 2 | ENCODES a protein that exhibits cytidine deaminase activity (ortholog); INVOLVED IN cytidine to uridine editing (ortholog); mRNA modification (ortholog); positive regulation of gene expression via chromosomal CpG island demethylation (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17beta -estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 9 | 20062561 | 20076074 | Rat | 62 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307800 | Apobec3 | apolipoprotein B mRNA editing enzyme catalytic subunit 3 | ENCODES a protein that exhibits cytidine deaminase activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); clearance of foreign intracellular DNA (ortholog); defense response to virus (ortholog); ASSOCIATED WITH Murine Acquired Immunodeficiency Syndrome (ortholog); FOUND IN cyt oplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH acetamide; fipronil; paracetamol | 7 | 113314196 | 113333306 | Rat | 78 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310625 | Apoh | apolipoprotein H | ENCODES a protein that exhibits lipid binding; identical protein binding (ortholog); lipase binding (ortholog); INVOLVED IN animal organ regeneration; negative regulation of respiratory burst; positive regulation of triglyceride catabolic process; PARTICIPATES IN coagulation cascade pathway; ASSOCIA TED WITH Chemical and Drug Induced Liver Injury; myocardial infarction; thrombosis; FOUND IN cell surface; extracellular space; chylomicron (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 93841992 | 93855897 | Rat | 162 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306480 | Apol3l1 | apolipoprotein L3 like 1 | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN lipid transport (inferred); lipoprotein metabolic process (inferred); FOUND IN extracellular region (inferred) | 7 | 111169307 | 111178306 | Rat | 4 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1311384 | Apon | apolipoprotein N | INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 7 | 1271514 | 1272917 | Rat | 25 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306223 | Aqr | aquarius intron-binding spliceosomal factor | ENCODES a protein that exhibits 3'-5' RNA helicase activity (ortholog); single-stranded RNA binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (ortholog); nucleoplasm (ortholog); nucleus (ortholog); IN TERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 3 | 121329287 | 121399375 | Rat | 105 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305342 | Arhgap9 | Rho GTPase activating protein 9 | ENCODES a protein that exhibits GTPase activator activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); INVOLVED IN signal transduction (inferred); ASSOCIATED WITH coronary artery vasospasm (ortholog); Experimental Liver Cirrhosis (ortholog); INTERACTS WITH 1-naphthyl isot hiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 7 | 65034023 | 65042336 | Rat | 91 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1305383 | Arhgdib | Rho GDP dissociation inhibitor beta | ENCODES a protein that exhibits GTPase activity (ortholog); Rho GDP-dissociation inhibitor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN cellular response to redox state; negative regulation of trophoblast cell migration (ortholog); regulation of Rho protein signal transduction ( ortholog); PARTICIPATES IN neurotrophic factor signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); Experimental Liver Cirrhosis (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 4 | 171554139 | 171573057 | Rat | 206 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310376 | Arhgef39 | Rho guanine nucleotide exchange factor 39 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN positive regulation of cell migration (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2- thiouracil; acetamide | 5 | 62548300 | 62551870 | Rat | 89 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311041 | Arid5a | AT-rich interaction domain 5A | ENCODES a protein that exhibits chromatin binding (ortholog); identical protein binding (ortholog); mRNA 3'-UTR AU-rich region binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to lipopolysaccharide (ortholog); chondrocyte differentiation (ortholog) ; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol | 9 | 46030513 | 46058729 | Rat | 132 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305535 | Arl6 | ARF like GTPase 6 | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); metal ion binding (inferred); INVOLVED IN brain development (ortholog); cilium assembly (ortholog); fat cell differentiation (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH Bardet-B iedl syndrome (ortholog); Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 3 (ortholog); FOUND IN ciliary tip (ortholog); cilium (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; acrylamide | 11 | 54180271 | 54207136 | Rat | 98 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1303337 | Arl9 | ARF like GTPase 9 | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); metal ion binding (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; copper atom | 14 | 31511845 | 31521038 | Rat | 43 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560393 | Armc1 | armadillo repeat containing 1 | ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN intracellular distribution of mitochondria (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 2 | 103524333 | 103568355 | Rat | 60 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1306691 | Armc6 | armadillo repeat containing 6 | INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol | 16 | 19225058 | 19235479 | Rat | 56 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1310096 | Arpc4 | actin related protein 2/3 complex, subunit 4 | ENCODES a protein that exhibits actin filament binding (ortholog); enzyme binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN Arp2/3 complex-mediated actin nucleation (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transpo rt pathway; platelet-derived growth factor signaling pathway; Rab family mediated signaling pathway; ASSOCIATED WITH Acute Otitis Media (ortholog); Developmental Delay, Language Impairment, and Ocular Abnormalities (ortholog); Down syndrome (ortholog); FOUND IN Arp2/3 protein complex (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 148077799 | 148088427 | Rat | 108 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310381 | Arsa | arylsulfatase A | ENCODES a protein that exhibits arylsulfatase activity; calcium ion binding (ortholog); sulfuric ester hydrolase activity (ortholog); INVOLVED IN autophagy; response to estrogen; response to ethanol; PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH hypothyroidism; Autosomal Sideroblastic Anemia (ortholog); citrullinemia (ortholog); FOUND IN acrosomal vesicle; endosome; extracellular space; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene | 7 | 122422971 | 122426971 | Rat | 138 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304917 | Arsl | arylsulfatase L | ENCODES a protein that exhibits arylsulfatase activity (ortholog); INVOLVED IN female pregnancy (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); chondrodysplasia punctata (ortholog); Coffin-Siris syndrome 1 (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetra chlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A | 2 | 120966992 | 120975015 | Rat | 49 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1306655 | Arvcf | ARVCF, delta catenin family member | ENCODES a protein that exhibits cadherin binding (ortholog); INVOLVED IN RNA splicing (ortholog); ASSOCIATED WITH COVID-19 (ortholog); DiGeorge syndrome (ortholog); long QT syndrome (ortholog); FOUND IN adherens junction (ortholog); cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH 17be ta-estradiol; acetamide; amphetamine | 11 | 96092451 | 96150144 | Rat | 124 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 1310760 | Asb1 | ankyrin repeat and SOCS box-containing 1 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN male genitalia development (ortholog); protein ubiquitination (ortholog); FOUND IN ubiquitin ligase complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thi ouracil | 9 | 99566852 | 99588321 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563114 | Asb4 | ankyrin repeat and SOCS box-containing 4 | ENCODES a protein that exhibits enzyme binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN positive regulation of vasculogenesis (ortholog); protein autoubiquitination (ortholog); ASSOCIATED WITH pre-eclampsia (ortholog); FOUND I N Cul2-RING ubiquitin ligase complex (ortholog); Cul5-RING ubiquitin ligase complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 4 | 34473527 | 34511163 | Rat | 64 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309246 | Asb8 | ankyrin repeat and SOCS box-containing 8 | INVOLVED IN intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diuron | 7 | 131140455 | 131176648 | Rat | 49 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304918 | Asf1b | anti-silencing function 1B histone chaperone | ENCODES a protein that exhibits histone binding (ortholog); histone chaperone activity (ortholog); INVOLVED IN blastocyst hatching (ortholog); nucleosome assembly (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH breast cancer (ortholog); castration-resistant prostate carcino ma (ortholog); hepatocellular carcinoma (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 41085786 | 41100352 | Rat | 200 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549776 | Aspn | asporin | ENCODES a protein that exhibits calcium ion binding (ortholog); INVOLVED IN response to fluoride; bone mineralization (ortholog); negative regulation of tooth mineralization (ortholog); ASSOCIATED WITH ankylosing spondylitis (ortholog); degenerative disc disease (ortholog); Experimental Liver Cirrho sis (ortholog); FOUND IN cell projection; extracellular matrix (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 17 | 15286338 | 15310567 | Rat | 115 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307360 | Atf1 | activating transcription factor 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; protein-containing complex binding; sequence-specific DNA binding; INVOLVED IN positive regulation of DNA replication; positive regulation of neuron projection development; positive regulation of t ranscription by RNA polymerase II; ASSOCIATED WITH polycystic kidney disease; polycystic ovary syndrome (ortholog); FOUND IN transcription regulator complex; ATF1-ATF4 transcription factor complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 133240774 | 133283488 | Rat | 163 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303317 | Atf6b | activating transcription factor 6 beta | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of ATF6-mediate d unfolded protein response (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); response to endoplasmic reticulum stress (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN endoplasmic reticulum membrane (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-phenylbutyric acid; bisphenol A | 20 | 4095534 | 4103534 | Rat | 116 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308303 | Atp6v0b | ATPase H+ transporting V0 subunit B | ENCODES a protein that exhibits proton transmembrane transporter activity (ortholog); INVOLVED IN monoatomic ion transport (inferred); proton transmembrane transport (inferred); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; FOUND IN endosome ( ortholog); membrane (ortholog); proton-transporting V-type ATPase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 5 | 136708823 | 136710339 | Rat | 115 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1306159 | Atp6v0d1 | ATPase H+ transporting V0 subunit D1 | ENCODES a protein that exhibits protein-containing complex binding; proton transmembrane transporter activity (ortholog); proton-transporting ATPase activity, rotational mechanism (ortholog); INVOLVED IN cellular response to increased oxygen levels (ortholog); intracellular iron ion homeostasis (ort holog); synaptic vesicle lumen acidification (ortholog); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; ASSOCIATED WITH cardiomyopathy (ortholog); lipodystrophy (ortholog); FOUND IN apical plasma membrane; axon terminus; protein-containing complex; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 19 | 50313268 | 50357248 | Rat | 161 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303186 | Atp6v1g2 | ATPase H+ transporting V1 subunit G2 | ENCODES a protein that exhibits proton-transporting ATPase activity, rotational mechanism (ortholog); INVOLVED IN synaptic vesicle lumen acidification (ortholog); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; FOUND IN extrinsic component of sy naptic vesicle membrane; synaptic vesicle membrane (ortholog); vacuolar proton-transporting V-type ATPase complex (ortholog); INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; ammonium chloride; bisphenol A | 20 | 3592374 | 3595986 | Rat | 77 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307047 | Atxn7l2 | ataxin 7-like 2 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; endosulfan | 2 | 198527066 | 198535899 | Rat | 45 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303211 | Aurkaip1 | aurora kinase A interacting protein 1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of mRNA splicing, via spliceosome (inferred); regulation of RNA splicing (inferred); FOUND IN cyclin L-CDK11 complex (inferre d); nuclear speck (inferred); nucleoplasm (inferred); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 5 | 171717349 | 171719123 | Rat | 28 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311968 | B3gat3 | beta-1,3-glucuronyltransferase 3 | ENCODES a protein that exhibits galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity (ortholog); glucuronosyltransferase activity (ortholog); protein phosphatase activator activity (ortholog); INVOLVED IN chondroitin sulfate proteoglycan biosynthetic process (ortholog); dermata n sulfate proteoglycan biosynthetic process (ortholog); glycosaminoglycan biosynthetic process (ortholog); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; heparan sulfate biosynthetic pathway; ASSOCIATED WITH BCARD syndrome (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cis-Golgi network (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose; aldehydo-D-glucosamine | 1 | 215246453 | 215253033 | Rat | 106 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309214 | B4galt7 | beta-1,4-galactosyltransferase 7 | ENCODES a protein that exhibits beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity (ortholog); galactosyltransferase activity (ortholog); manganese ion binding (ortholog); INVOLVED IN glycosaminoglycan biosynthetic process (ortholog); negative regulation of fibroblast prol iferation (ortholog); protein N-linked glycosylation (ortholog); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; heparan sulfate biosynthetic pathway; ASSOCIATED WITH BCARD syndrome (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); FOUND IN Golgi apparatus (ortholog); membrane (ortholog); INTERACTS WITH acrylamide; bisphenol A; gentamycin | 17 | 9023667 | 9032742 | Rat | 101 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308134 | Bacc1 | BPTF associated chromatin complex component 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN chromatin organization (inferred); FOUND IN MLL1 complex (ortholog); NURF complex (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 55450648 | 55453409 | Rat | 49 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307794 | Bag3 | BAG cochaperone 3 | ENCODES a protein that exhibits protein-containing complex binding; adenyl-nucleotide exchange factor activity (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN autophagosome assembly; chaperone-mediated autophagy; negative regulation of apoptotic process; ASSOCIATED WITH Experim ental Seizures; glioblastoma; Reperfusion Injury; FOUND IN stress fiber; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 192533460 | 192557281 | Rat | 350 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307464 | Banp | Btg3 associated nuclear protein | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Ependymomas (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,3,5-trinitro-1,3,5-t riazinane; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine | 19 | 66916417 | 66994286 | Rat | 116 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560748 | Bbs10 | Bardet-Biedl syndrome 10 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN chaperone-mediated protein complex assembly (ortholog); cone retinal bipolar cell differentiation (ortholog); DNA damage response (ortholog); ASSOCIATED WITH Bardet-Biedl syndr ome (ortholog); Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 10 (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 7 | 48637324 | 48640395 | Rat | 96 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310718 | Bbs5 | Bardet-Biedl syndrome 5 | ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN cilium assembly (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 1 (ortholog); Bardet-Bi edl syndrome 5 (ortholog); FOUND IN axoneme (ortholog); BBSome (ortholog); centriolar satellite (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A | 3 | 74818104 | 74839658 | Rat | 71 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309264 | Bbs7 | Bardet-Biedl syndrome 7 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN brain development (ortholog); eye development (ortholog); fat cell differentiation (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 1 (orthol og); Bardet-Biedl Syndrome 1/7, Digenic (ortholog); FOUND IN axoneme (ortholog); BBSome (ortholog); centrosome (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 4,4'-diaminodiphenylmethane; bisphenol A | 2 | 121362884 | 121402473 | Rat | 90 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309769 | Bbx | BBX high mobility group box domain containing | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN bone development (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 11 | 63850034 | 64097700 | Rat | 109 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359431 | Bcap29 | B-cell receptor-associated protein 29 | INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); protein localization to endoplasmic reticulum exit site (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodi oxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 6 | 53910209 | 53950206 | Rat | 102 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306485 | Bcas2 | BCAS2, pre-mRNA processing factor | INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); dendrite development (ortholog); dendrite morphogenesis (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH breast cancer (ortholog); diffuse large B-cell lymphoma (ortholog); FOUND IN DNA replication factor A complex (o rtholog); nuclear speck (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; fipronil; tolcapone | 2 | 193381000 | 193388881 | Rat | 102 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309345 | Bcl6 | BCL6, transcription repressor | ENCODES a protein that exhibits chromatin binding (ortholog); chromatin DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); B cell differentiation (ortholog); cell morphogenesis (ortholog); PARTICIPATES IN interleukin- 4 signaling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); diffuse large B-cell lymphoma (ortholog); Gastrointestinal Hemorrhage (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); paraspeckles (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 11 | 90358753 | 90382049 | Rat | 351 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359658 | Bcs1l | BCS1 ubiquinol-cytochrome c reductase complex chaperone | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); INVOLVED IN mitochondrial respiratory chain complex I assembly (ortholog); mitochondrial respiratory chain complex III assembly (ortholog); mitochondrial respiratory chain complex IV assembly (ortholog); ASSOCIATED WITH Bjornstad sy ndrome (ortholog); brain disease (ortholog); epilepsy (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 9 | 83614045 | 83618052 | Rat | 109 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306729 | Bicdl2 | BICD family like cargo adaptor 2 | ENCODES a protein that exhibits small GTPase binding (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; amphetamine | 10 | 13196205 | 13204642 | Rat | 45 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308859 | Blk | BLK proto-oncogene, Src family tyrosine kinase | ENCODES a protein that exhibits non-membrane spanning protein tyrosine kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN B cell receptor signaling pathway (ortholog); peptidyl-tyrosine phosphorylation (ortholog); positive regulation of insulin secretion (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; glypican signaling pathway; ASSOCIATED WITH Myocardial Reperfusion Injury; diabetes mellitus (ortholog); Kawasaki disease (ortholog); FOUND IN cytosol (inferred); plasma membrane (inferred); INTERACTS WITH aflatoxin B1; alpha-Zearalanol; decabromodiphenyl ether | 15 | 41802701 | 41841004 | Rat | 106 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304668 | Blmh | bleomycin hydrolase | ENCODES a protein that exhibits aminopeptidase activity (ortholog); identical protein binding (ortholog); peptidase activity (ortholog); INVOLVED IN response to toxic substance (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Alzheimer's disease 1 (ortholog); FOUND IN cytoplas m (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 62270170 | 62313349 | Rat | 107 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306080 | Blvrb | biliverdin reductase B | ENCODES a protein that exhibits biliverdin reductase [NAD(P)H] activity (ortholog); peptidyl-cysteine S-nitrosylase activity (ortholog); riboflavin reductase (NADPH) activity (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); bone marrow development (ortholog); cell fate specification (o rtholog); PARTICIPATES IN porphyrin and chlorophyll metabolic pathway; riboflavin metabolic pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); esophagus squamous cell carcinoma (ortholog); Stomach Neoplasms (ortholog); FOUND IN terminal bouton; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide | 1 | 91866258 | 91883921 | Rat | 212 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307403 | Bmi1 | BMI1 proto-oncogene, polycomb ring finger | ENCODES a protein that exhibits chromatin binding (ortholog); promoter-specific chromatin binding (ortholog); RING-like zinc finger domain binding (ortholog); INVOLVED IN cellular response to dexamethasone stimulus; cellular response to interleukin-1; regulation of kidney development; PARTICIPATES I N histone modification pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); acute pancreatitis (ortholog); chronic pancreatitis (ortholog); FOUND IN heterochromatin (ortholog); nuclear body (ortholog); nucleus (ortholog); INTERACTS WITH amphetamine; bisphenol A; cadmium atom | 17 | 86240683 | 86250044 | Rat | 245 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1309478 | Bnipl | BCL2 interacting protein like | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN apoptotic process (ortholog); negative regulation of cell population proliferation (ortholog); regulation of growth rate (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH furan; paraquat; tric hloroethene | 2 | 185507591 | 185519415 | Rat | 52 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307624 | Borcs5 | BLOC-1 related complex subunit 5 | INVOLVED IN axon development (ortholog); lysosome localization (ortholog); mitochondrion organization (ortholog); ASSOCIATED WITH Agenesis of Corpus Callosum (ortholog); colorectal adenocarcinoma (ortholog); FOUND IN axon (ortholog); BORC complex (ortholog); cytoplasmic side of lysosomal membrane (o rtholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; paracetamol | 4 | 169190025 | 169272335 | Rat | 72 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307572 | Bphl | biphenyl hydrolase like | ENCODES a protein that exhibits alpha-amino-acid esterase activity (ortholog); serine hydrolase activity (ortholog); INVOLVED IN homocysteine metabolic process (ortholog); xenobiotic metabolic process (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlor odibenzodioxine; 2,6-dinitrotoluene | 17 | 31006283 | 31042631 | Rat | 123 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306678 | Brdt | bromodomain testis associated | ENCODES a protein that exhibits histone binding (ortholog); histone H4 reader activity (ortholog); INVOLVED IN chromatin remodeling; spermatogenesis; male meiosis I (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH azoospermia (ortholog); oligospermia (ortholog); primary ovar ian insufficiency (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH allethrin; bisphenol A; cyhalothrin | 14 | 2532275 | 2590780 | Rat | 85 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1306301 | Btbd10 | BTB domain containing 10 | INVOLVED IN positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); FOUND IN cytoplasm (ortholog); fibrillar center (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 176865817 | 176923663 | Rat | 74 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308095 | Btf3 | basic transcription factor 3 | INVOLVED IN in utero embryonic development (ortholog); negative regulation of protein localization to endoplasmic reticulum (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 2 | 31394010 | 31401138 | Rat | 111 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303262 | Btnl3 | butyrophilin-like 3 | INVOLVED IN extrathymic T cell selection (inferred); FOUND IN cell surface (inferred); membrane (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; pregnenolone 16alpha-carbonitrile | 20 | 4475984 | 4490955 | Rat | 6 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1560327 | C11h21orf140 | similar to human chromosome 21 open reading frame 140 | INTERACTS WITH 4,4'-sulfonyldiphenol (ortholog); clothianidin (ortholog); titanium dioxide (ortholog) | 11 | 45035613 | 45038181 | Rat | 3 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1566099 | C13h1orf53 | similar to human chromosome 1 open reading frame 53 | FOUND IN mitochondrion (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 13 | 52965244 | 52970432 | Rat | 46 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565445 | C16h13orf46 | similar to human chromosome 13 open reading frame 46 | INTERACTS WITH aristolochic acid A (ortholog); Dibutyl phosphate (ortholog); Licochalcone B (ortholog) | 16 | 82677041 | 82689807 | Rat | 5 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308706 | C19h16orf87 | similar to human chromosome 16 open reading frame 87 | INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 19 | 37800187 | 37827091 | Rat | 44 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560600 | C1d | C1D nuclear receptor corepressor | ENCODES a protein that exhibits DNA binding (ortholog); nuclear receptor binding (ortholog); RNA binding (ortholog); INVOLVED IN maturation of 5.8S rRNA (ortholog); negative regulation of DNA-templated transcription (ortholog); PARTICIPATES IN ribosome biogenesis pathway; RNA degradation pathway; FO UND IN nucleolus (ortholog); nucleoplasm (ortholog); transcription repressor complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; cadmium dichloride | 14 | 95862550 | 95874796 | Rat | 74 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562283 | C1h10orf120 | similar to human chromosome 10 open reading frame 120 | INTERACTS WITH bisphenol A; benzo[a]pyrene (ortholog); resveratrol (ortholog) | 1 | 195340624 | 195343676 | Rat | 5 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305010 | C1qtnf3 | C1q and TNF related 3 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN fat cell differentiation (ortholog); glucose homeostasis (ortholog); intracellular triglyceride homeostasis (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); protein-containing compl ex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 2 | 61644225 | 61666640 | Rat | 111 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311006 | C1qtnf4 | C1q and TNF related 4 | ENCODES a protein that exhibits cytokine activity (inferred); INVOLVED IN cell surface receptor signaling pathway via STAT (ortholog); gene expression (ortholog); inflammatory response (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachl orodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 3 | 97310220 | 97328818 | Rat | 101 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564149 | C20h21orf58 | similar to human chromosome 21 open reading frame 58 | INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; bisphenol A | 20 | 12165853 | 12187271 | Rat | 50 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310281 | C2cd2l | C2CD2-like | ENCODES a protein that exhibits insulin binding (ortholog); phosphatidylinositol binding (ortholog); phosphatidylinositol transfer activity (ortholog); INVOLVED IN positive regulation of insulin secretion involved in cellular response to glucose stimulus (ortholog); ASSOCIATED WITH RASopathy (orthol og); FOUND IN cortical endoplasmic reticulum (ortholog); cytoplasmic side of apical plasma membrane (ortholog); endoplasmic reticulum-plasma membrane contact site (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 8 | 53544887 | 53557127 | Rat | 104 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1565059 | C2h3orf33 | similar to human chromosome 3 open reading frame 33 | INVOLVED IN negative regulation of ERK1 and ERK2 cascade (ortholog); FOUND IN extracellular space (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acrylamide; bisphenol A | 2 | 150522758 | 150554007 | Rat | 41 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560010 | C2h4orf46 | similar to human chromosome 4 open reading frame 46 | FOUND IN cytosol (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 2 | 167061141 | 167064273 | Rat | 52 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561517 | C3h20orf144 | similar to human chromosome 20 open reading frame 144 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; genistein | 3 | 163514340 | 163515531 | Rat | 8 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1306746 | C4h2orf42 | similar to human chromosome 2 open reading frame 42 | FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate | 4 | 120445032 | 120474227 | Rat | 49 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311517 | C5h1orf159 | similar to human chromosome 1 open reading frame 159 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-aminopyridine; acetamide | 5 | 171983700 | 172001373 | Rat | 36 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561648 | C7h12orf56 | similar to human chromosome 12 open reading frame 56 | INTERACTS WITH bisphenol A; genistein; paracetamol | 7 | 59055283 | 59106900 | Rat | 23 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359634 | C7h22orf23 | similar to human chromosome 22 open reading frame 23 | INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; bisphenol A | 7 | 112585341 | 112592938 | Rat | 18 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306612 | Ca12 | carbonic anhydrase 12 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); lyase activity (inferred); metal ion binding (inferred); INVOLVED IN estrous cycle; chloride ion homeostasis (ortholog); ASSOCIATED WITH colon adenocarcinoma (ortholog); colorectal adenocarcinoma (ortholog); colorectal carcin oma (ortholog); FOUND IN apical plasma membrane; basolateral plasma membrane; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 76169723 | 76225465 | Rat | 186 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560453 | Ca13 | carbonic anhydrase 13 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); lyase activity (inferred); metal ion binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 2 | 88649643 | 88680763 | Rat | 101 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306426 | Ca9 | carbonic anhydrase 9 | ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); molecular function activator activity (ortholog); zinc ion binding (ortholog); INVOLVED IN response to hypoxia; response to testosterone; response to xenobiotic stimulus; PARTICIPATES IN hypoxia inducible factor pathway; ASSO CIATED WITH Experimental Mammary Neoplasms; Right Ventricular Hypertrophy; Anaplasia (ortholog); FOUND IN basolateral plasma membrane; plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 5 | 62559024 | 62565626 | Rat | 206 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308945 | Cab39l | calcium binding protein 39-like | PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; beta-naphthoflavone | 15 | 37782778 | 37885191 | Rat | 92 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310999 | Cadm1 | cell adhesion molecule 1 | ENCODES a protein that exhibits cell adhesion molecule binding; identical protein binding (ortholog); PDZ domain binding (ortholog); INVOLVED IN liver development; negative regulation of ERBB4 signaling pathway; negative regulation of protein phosphorylation; ASSOCIATED WITH hepatocellular carcinoma ; lung adenocarcinoma; autistic disorder (ortholog); FOUND IN dendrite; postsynaptic density; axon (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 8 | 56744374 | 57075264 | Rat | 268 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1309243 | Calr3 | calreticulin 3 | ENCODES a protein that exhibits calcium ion binding (ortholog); protein folding chaperone (ortholog); INVOLVED IN cell differentiation (inferred); protein folding (inferred); spermatogenesis (inferred); ASSOCIATED WITH arrhythmogenic right ventricular cardiomyopathy (ortholog); cardiomyopathy (ortho log); dilated cardiomyopathy (ortholog); FOUND IN endoplasmic reticulum lumen (ortholog); nuclear envelope (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene | 16 | 17430105 | 17456777 | Rat | 76 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562703 | Camta1 | calmodulin binding transcription activator 1 | ENCODES a protein that exhibits sequence-specific DNA binding (ortholog); INVOLVED IN neuromuscular process controlling balance (ortholog); positive regulation of calcineurin-NFAT signaling cascade (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Deve lopmental Disease (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 5 | 166791639 | 167639502 | Rat | 123 | old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1306842 | Car7 | carbonic anhydrase 7 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); lyase activity (inferred); metal ion binding (inferred); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil | 19 | 435520 | 444927 | Rat | 63 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565450 | Catspert | catsper channel auxiliary subunit tau | INVOLVED IN calcium ion transmembrane transport (ortholog); flagellated sperm motility (ortholog); protein-containing complex assembly (ortholog); ASSOCIATED WITH prostate cancer (ortholog); spermatogenic failure 68 (ortholog); FOUND IN CatSper complex (ortholog); sperm flagellum (ortholog); sperm p rincipal piece (ortholog); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); all-trans-retinoic acid (ortholog) | 9 | 67929069 | 68024993 | Rat | 32 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1549705 | Cbx3 | chromobox 3 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); enzyme binding (ortholog); histone H1K26me1 reader activity (ortholog); INVOLVED IN cellular response to dexamethasone stimulus; DNA damage response (ortholog); gene expression (ortholog); ASSOCIATED WITH Habitual A bortions (ortholog); prostate cancer (ortholog); FOUND IN senescence-associated heterochromatin focus; chromatin (ortholog); chromocenter (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 4 | 81876155 | 81889912 | Rat | 170 | UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1561171 | Ccdc126 | coiled-coil domain containing 126 | ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane | 4 | 79628483 | 79649513 | Rat | 60 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560860 | Ccdc144a | coiled-coil domain containing 144A | INTERACTS WITH (+)-catechin (ortholog); aflatoxin B1 (ortholog); Aflatoxin B2 alpha (ortholog) | 17 | 59503255 | 59542745 | Rat | 16 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1308031 | Ccdc159 | coiled-coil domain containing 159 | INVOLVED IN gene expression (ortholog); regulation of phosphatase activity (ortholog); single fertilization (ortholog); ASSOCIATED WITH male infertility due to acephalic spermatozoa (ortholog); FOUND IN sperm head-tail coupling apparatus (ortholog); INTERACTS WITH (+)-schisandrin B; acrylamide; bisp henol A | 8 | 28733988 | 28742646 | Rat | 48 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1559811 | Ccdc70 | coiled-coil domain containing 70 | FOUND IN plasma membrane (ortholog); INTERACTS WITH bisphenol A; 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog); 1,2-dichloroethane (ortholog) | 16 | 76739795 | 76745019 | Rat | 21 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560244 | Ccdc78 | coiled-coil domain containing 78 | INVOLVED IN de novo centriole assembly involved in multi-ciliated epithelial cell differentiation (ortholog); skeletal muscle contraction (ortholog); ASSOCIATED WITH centronuclear myopathy (ortholog); centronuclear myopathy 4 (ortholog); congenital structural myopathy (ortholog); FOUND IN centriole (ortholog); cytoplasm (ortholog); deuterosome (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 15312403 | 15316800 | Rat | 45 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1305530 | Ccl25 | C-C motif chemokine ligand 25 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cell chemotaxis (ortholog); chemotaxis (ortholog); PARTIC IPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH Jaundice; pleurisy (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole | 12 | 7505231 | 7514402 | Rat | 95 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561930 | Ccnb1ip1 | cyclin B1 interacting protein 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN blastocyst formation (ortholog); chiasma assembly (ortholog); reciprocal meiotic recombination (ortholog); FOUND IN condensed nuclear chromosome (ortholog); synaptonemal complex (ortholog); INTERACTS WITH 2,3,7,8-tetra chlorodibenzodioxine; bisphenol A; gentamycin | 15 | 26488462 | 26504167 | Rat | 72 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305002 | Ccng2 | cyclin G2 | INVOLVED IN regulation of cell cycle (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH colon cancer (ortholog); Experimental Liver Neoplasms (ortholog); head and neck cancer (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiou racil; acrylamide | 14 | 15088694 | 15097190 | Rat | 266 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304763 | Cct6a | chaperonin containing TCP1 subunit 6A | ENCODES a protein that exhibits protein folding chaperone (ortholog); WD40-repeat domain binding (ortholog); INVOLVED IN binding of sperm to zona pellucida (ortholog); positive regulation of establishment of protein localization to telomere (ortholog); positive regulation of protein localization to Cajal body (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); chaperonin-containing T-complex (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 32508842 | 32519072 | Rat | 156 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311741 | Cd2bp2 | Cd2 (cytoplasmic tail) binding protein 2 | ENCODES a protein that exhibits ribonucleoprotein complex binding (ortholog); INVOLVED IN mRNA processing (inferred); RNA splicing (inferred); FOUND IN cytosol (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trin itrotoluene | 1 | 191239899 | 191244395 | Rat | 90 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565355 | Cd36l1 | CD36 molecule like 1 | ENCODES a protein that exhibits scavenger receptor activity; thrombospondin receptor activity; transforming growth factor beta binding; INVOLVED IN amyloid-beta clearance by cellular catabolic process; energy homeostasis; receptor-mediated endocytosis; PARTICIPATES IN cell-extracellular matrix signa ling pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; malaria pathway; FOUND IN brush border membrane; cell surface; Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 4 | 18316806 | 18357863 | Rat | 58 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1308526 | Cd5l | Cd5 molecule-like | INVOLVED IN positive regulation of complement-dependent cytotoxicity (ortholog); regulation of complement activation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 2 | 175088915 | 175099928 | Rat | 103 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305970 | Cd68 | Cd68 molecule | INVOLVED IN response to ethanol; cellular response to lipopolysaccharide (ortholog); cellular response to nutrient levels (ortholog); ASSOCIATED WITH metabolic dysfunction and alcohol associated liver disease; metabolic dysfunction-associated steatohepatitis; acquired immunodeficiency syndrome (orth olog); FOUND IN lysosome (ortholog); plasma membrane (ortholog); INTERACTS WITH (-)-cotinine; (S)-nicotine; 1-naphthyl isothiocyanate | 10 | 54880562 | 54882441 | Rat | 352 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310015 | Cd7 | Cd7 molecule | ENCODES a protein that exhibits transmembrane signaling receptor activity (ortholog); INVOLVED IN homeostasis of number of cells within a tissue (ortholog); positive regulation of T cell cytokine production (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Experimental Liv er Cirrhosis (ortholog); Spontaneous Abortions (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 10 | 106802373 | 106805269 | Rat | 61 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309677 | Cd83 | CD83 molecule | INVOLVED IN negative regulation of interleukin-4 production (ortholog); positive regulation of CD4-positive, alpha-beta T cell differentiation (ortholog); positive regulation of interleukin-10 production (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); Experimental Liver Cirrhosis (ortholog ); juvenile rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 17 | 21093281 | 21113223 | Rat | 211 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305076 | Cdc16 | cell division cycle 16 | INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); protein branched polyubiquitination (ortholog); protein K11-linked ubiquitination (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; ubiquitin/proteasome degradation pathway; FOUND IN anaphase-promoting complex (ort holog); centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 16 | 82475234 | 82498797 | Rat | 85 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307169 | Cdh19 | cadherin 19 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cell adhesion (inferred); cell-cell adhesion (inferred); homophilic cell-cell adhesion (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodib enzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 13 | 28450361 | 28561932 | Rat | 53 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308664 | Cdk2ap1 | cyclin-dependent kinase 2 associated protein 1 | ENCODES a protein that exhibits DNA polymerase binding (ortholog); INVOLVED IN face morphogenesis (ortholog); in utero embryonic development (ortholog); regulation of transcription by RNA polymerase II (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS W ITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 37910718 | 37919446 | Rat | 76 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309625 | Cdkl2 | cyclin dependent kinase like 2 | ENCODES a protein that exhibits ATP binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); kinase activity (inferred); INVOLVED IN regulation of cell cycle (inferred); ASSOCIATED WITH Disease Progression (ortholog); Experimental Mammary Neoplasms (ortholog); Neopla sm Metastasis (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 14 | 16312154 | 16347524 | Rat | 76 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310578 | Cdr2 | cerebellar degeneration-related protein 2 | INVOLVED IN alpha-beta T cell activation involved in immune response (ortholog); cell activation (ortholog); T cell anergy (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 184934128 | 184959036 | Rat | 110 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559593 | Ceacam11 | CEA cell adhesion molecule 11 | INTERACTS WITH ammonium chloride; bisphenol A | 1 | 87266896 | 87273132 | Rat | 5 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563607 | Cenpa | centromere protein A | ENCODES a protein that exhibits DNA binding (inferred); protein heterodimerization activity (inferred); structural constituent of chromatin (inferred); INVOLVED IN CENP-A containing chromatin assembly (ortholog); establishment of mitotic spindle orientation (ortholog); kinetochore assembly (ortholog ); ASSOCIATED WITH autoimmune disease (ortholog); hepatocellular carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN CENP-A containing chromatin (ortholog); CENP-A containing nucleosome (ortholog); chromosome, centromeric region (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17beta-estradiol | 6 | 31420062 | 31431703 | Rat | 232 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310953 | Cenpn | centromere protein N | INVOLVED IN CENP-A containing chromatin assembly (inferred); chromosome segregation (inferred); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil | 19 | 61880101 | 61902850 | Rat | 99 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311520 | Cep85 | centrosomal protein 85 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cell migration (ortholog); centriole assembly (ortholog); centriole replication (ortholog); FOUND IN cell cortex (ortholog); centriole (ortholog); centrosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrach lorodibenzodioxine; 2,4-dinitrotoluene | 5 | 151640316 | 151687891 | Rat | 98 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563046 | Cer1 | cerberus 1, DAN family BMP antagonist | ENCODES a protein that exhibits BMP binding (ortholog); morphogen activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN anterior/posterior axis specification (ortholog); anterior/posterior pattern specification (ortholog); bone mineralization (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; ASSOCIATED WITH Spinal Fractures (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH bisphenol A; trichloroethene; 1,2-dichloroethane (ortholog) | 5 | 102352364 | 102355720 | Rat | 86 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305974 | Cers1 | ceramide synthase 1 | ENCODES a protein that exhibits N-acyltransferase activity (ortholog); sphingosine N-acyltransferase activity (ortholog); INVOLVED IN brain development (ortholog); cellular response to dithiothreitol (ortholog); cellular response to mycotoxin (ortholog); ASSOCIATED WITH Perinatal Asphyxia; cerebella r ataxia (ortholog); Insulin Resistance (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH acrylamide; bisphenol A; furan | 16 | 19131271 | 19146480 | Rat | 74 | UniProt , old_protein_id | gene, protein-coding, REVIEWED [RefSeq] |
| 1564356 | Cers3 | ceramide synthase 3 | ENCODES a protein that exhibits sphingosine N-acyltransferase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); cornification (ortholog); epidermis development (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis (ortholog); autosomal recessive congenital ic hthyosis 9 (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 4,4'-sulfonyldiphenol; acrylamide | 1 | 129728136 | 129833182 | Rat | 70 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310371 | Cfap161 | cilia and flagella associated protein 161 | INVOLVED IN flagellated sperm motility (ortholog); gene expression (ortholog); motile cilium assembly (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); axonemal microtubule (ortholog); axoneme (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; fenvalerate | 1 | 147152923 | 147177821 | Rat | 42 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309594 | Cfap410 | cilia and flagella associated protein 410 | INVOLVED IN cilium assembly (ortholog); smoothened signaling pathway (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); axial spondylometaphyseal dysplasia (ortholog); cone dystrophy (ortholog); FOUND IN ciliary basal body (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTE RACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 20 | 10687506 | 10694366 | Rat | 67 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308151 | Cfap52 | cilia and flagella associated protein 52 | INVOLVED IN establishment of left/right asymmetry (ortholog); flagellated sperm motility (ortholog); gene expression (ortholog); ASSOCIATED WITH visceral heterotaxy 10 (ortholog); visceral heterotaxy 5 (ortholog); FOUND IN 9+2 motile cilium (ortholog); axonemal B tubule inner sheath (ortholog); axon emal microtubule (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 53112692 | 53153844 | Rat | 84 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310510 | Cfhr1 | complement factor H-related 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cytolysis by host of symbiont cells (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); age related macular degeneration 1 (ortholog); atypical hemolytic-uremic syndrome (ortholog); FOUND IN protein-containi ng complex (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 13 | 53946298 | 53961282 | Rat | 95 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307634 | Chaf1b | chromatin assembly factor 1 subunit B | INVOLVED IN DNA replication-dependent chromatin assembly (ortholog); nucleosome assembly (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Developmental Disabilities (ortholog); glioblastoma (ortholog); hepatocellular carcinoma (ortholog); FOUND IN CAF-1 complex (ortholog); c hromatin (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 46670560 | 46690739 | Rat | 161 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311283 | Champ1 | chromosome alignment maintaining phosphoprotein 1 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); protein localization to kinetochore (ortholog); protein localization to microtubule (ortholog); ASSOCIATED WITH autosomal domin ant intellectual developmental disorder 40 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); genetic disease (ortholog); FOUND IN condensed chromosome (ortholog); kinetochore (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 16 | 82436172 | 82447144 | Rat | 75 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307134 | Chchd1 | coiled-coil-helix-coiled-coil-helix domain containing 1 | INVOLVED IN mitochondrial translation (inferred); FOUND IN fibrillar center (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 15 | 3641973 | 3643155 | Rat | 79 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359417 | Chchd10 | coiled-coil-helix-coiled-coil-helix domain containing 10 | INVOLVED IN inner mitochondrial membrane organization (ortholog); mitochondrial membrane organization (ortholog); mitochondrion organization (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); frontotemporal dementia and/or amyotrophic lateral sclerosis 2 (ortholog); genetic diseas e (ortholog); FOUND IN MICOS complex (ortholog); mitochondrial intermembrane space (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 20 | 12725274 | 12730295 | Rat | 123 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307809 | Chchd5 | coiled-coil-helix-coiled-coil-helix domain containing 5 | FOUND IN mitochondrion (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 3 | 136815034 | 136819230 | Rat | 54 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1305646 | Chit1 | chitinase 1 | ENCODES a protein that exhibits chitinase activity (ortholog); endochitinase activity (ortholog); INVOLVED IN chitin catabolic process (ortholog); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; sialic acid storage disease pathway; ASSOCIATED WITH albuminuria; salt-sensi tive hypertension; ASSOCIATED WITH CHITOTRIOSIDASE DEFICIENCY (ortholog); Gaucher's disease (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 13 | 48117886 | 48165645 | Rat | 77 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359458 | Chpf | chondroitin polymerizing factor | ENCODES a protein that exhibits glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity (ortholog); glycosyltransferase activity (ortholog); N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity (ortholog); INVOLVED IN chondroitin sulf ate proteoglycan biosynthetic process (ortholog); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; ASSOCIATED WITH cerebrotendinous xanthomatosis (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine | 9 | 84411824 | 84416523 | Rat | 113 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305116 | Churc1 | churchill domain containing 1 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of DNA-templated transcription (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; acetamide | 6 | 101203778 | 101218364 | Rat | 51 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307481 | Ciao2a | cytosolic iron-sulfur assembly component 2A | INVOLVED IN iron-sulfur cluster assembly (ortholog); protein maturation (ortholog); PARTICIPATES IN cytosolic iron-sulfur cluster protein assembly pathway; ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN cytosol (ortholog); cytosolic [4Fe-4S] assembly targeting complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 8 | 75565620 | 75577542 | Rat | 78 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563395 | Cinp | cyclin-dependent kinase 2-interacting protein | ENCODES a protein that exhibits preribosome binding (ortholog); INVOLVED IN DNA replication (ortholog); regulation of ribosome biogenesis (ortholog); ribosomal large subunit biogenesis (ortholog); ASSOCIATED WITH epilepsy (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodib enzodioxine; 6-propyl-2-thiouracil; amitrole | 6 | 135698477 | 135720798 | Rat | 66 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303171 | Clcf1 | cardiotrophin-like cytokine factor 1 | ENCODES a protein that exhibits ciliary neurotrophic factor receptor binding (ortholog); cytokine activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN B cell differentiation (ortholog); cell surface receptor signaling pathway (ortholog); cell surface receptor signaling pathway via JAK-STAT (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH cold-induced sweating syndrome (ortholog); cold-induced sweating syndrome 2 (ortholog); COVID-19 (ortholog); FOUND IN CNTFR-CLCF1 complex (ortholog); CRLF-CLCF1 complex (ortholog); extracellular region (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 210937763 | 210947064 | Rat | 187 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309001 | Cldn23 | claudin 23 | ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN intracellular protein localization (ortholog); tight junction organization (ortholog); PARTICIPATES IN hepatitis C pathway; ASSOCIATED WITH atopic dermatitis (ortholog); FOUND IN bicellular tight junction (inferred) ; membrane (inferred); plasma membrane (inferred); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 63117045 | 63118769 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307932 | Cldn4 | claudin 4 | ENCODES a protein that exhibits chloride channel activity (inferred); structural molecule activity (inferred); INVOLVED IN circadian rhythm; female pregnancy; response to progesterone; PARTICIPATES IN hepatitis C pathway; ASSOCIATED WITH peptic esophagitis; Reperfusion Injury; Breast Neoplasms (orth olog); FOUND IN apical plasma membrane; apicolateral plasma membrane; basal plasma membrane; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene | 12 | 27388160 | 27389958 | Rat | 284 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308575 | Cldn8 | claudin 8 | PARTICIPATES IN hepatitis C pathway; ASSOCIATED WITH malignant mesothelioma (ortholog); FOUND IN apicolateral plasma membrane (ortholog); basolateral plasma membrane (ortholog); bicellular tight junction (ortholog); INTERACTS WITH 17beta-estradiol; 3,3',5,5'-tetrabromobisphenol A; 3-chloropropane-1, 2-diol | 11 | 41362081 | 41364330 | Rat | 69 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306232 | Clec14a | C-type lectin domain containing 14A | ENCODES a protein that exhibits extracellular matrix protein binding (ortholog); INVOLVED IN cell migration involved in sprouting angiogenesis (ortholog); lymphangiogenesis (ortholog); sprouting angiogenesis (ortholog); FOUND IN endoplasmic reticulum (ortholog); external side of plasma membrane (ort holog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione | 6 | 81616414 | 81619556 | Rat | 94 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310274 | Clk4 | CDC-like kinase 4 | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN peptidyl-tyrosine phosphorylation (ortholog); protein autophosphorylation (ortholog); regulation of RNA splicing (ortholog); FOUND IN nucleus (ortholog); INTE RACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 36024364 | 36042366 | Rat | 116 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359537 | Cln3 | CLN3 lysosomal/endosomal transmembrane protein, battenin | ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); glycolipid binding (ortholog); sulfatide binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); action potential (ortholog); amino acid transport (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholo g); Disease Progression (ortholog); epilepsy (ortholog); FOUND IN endosome; autolysosome (ortholog); autophagosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 1 | 190586649 | 190600034 | Rat | 248 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310959 | Clptm1 | CLPTM1 regulator of GABA type A receptor forward trafficking | ENCODES a protein that exhibits GABA receptor binding (ortholog); INVOLVED IN regulation of postsynaptic membrane neurotransmitter receptor levels; inhibitory chemical synaptic transmission (ortholog); memory (ortholog); ASSOCIATED WITH pancreatic cancer (ortholog); FOUND IN GABA-ergic synapse; exte rnal side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 1 | 88417447 | 88449047 | Rat | 94 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310911 | Cmas | cytidine monophosphate N-acetylneuraminic acid synthetase | ENCODES a protein that exhibits N-acylneuraminate cytidylyltransferase activity (ortholog); INVOLVED IN CMP-N-acetylneuraminate biosynthetic process (ortholog); N-acetylneuraminate metabolic process (ortholog); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; sialic acid storage disease pathway; ASSOCIATED WITH focal segmental glomerulosclerosis (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 4 | 177449801 | 177468117 | Rat | 94 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308763 | Cmtm3 | CKLF-like MARVEL transmembrane domain containing 3 | INVOLVED IN blastocyst hatching (ortholog); positive regulation of B cell receptor signaling pathway (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17bet a-estradiol; 17beta-estradiol 3-benzoate | 19 | 629000 | 637152 | Rat | 116 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307765 | Cmtm6 | CKLF-like MARVEL transmembrane domain containing 6 | INVOLVED IN camera-type eye development (ortholog); corneal epithelial cell differentiation (ortholog); endocytic recycling (ortholog); FOUND IN early endosome membrane (ortholog); plasma membrane (ortholog); recycling endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2 ,3,7,8-Tetrachlorodibenzofuran; 3H-1,2-dithiole-3-thione | 8 | 123301131 | 123319230 | Rat | 108 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305313 | Cnot7 | CCR4-NOT transcription complex, subunit 7 | ENCODES a protein that exhibits 3'-5'-RNA exonuclease activity (ortholog); DNA-binding transcription factor binding (ortholog); piRNA binding (ortholog); INVOLVED IN deadenylation-dependent decapping of nuclear-transcribed mRNA (ortholog); defense response to virus (ortholog); miRNA-mediated gene si lencing by mRNA destabilization (ortholog); PARTICIPATES IN microRNA pathway; RNA degradation pathway; ASSOCIATED WITH male infertility; FOUND IN CCR4-NOT complex (ortholog); cytoplasm (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium atom | 16 | 58478882 | 58498046 | Rat | 159 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306401 | Cnot8 | CCR4-NOT transcription complex, subunit 8 | ENCODES a protein that exhibits 3'-5'-RNA exonuclease activity (ortholog); poly(A)-specific ribonuclease activity (ortholog); INVOLVED IN miRNA-mediated gene silencing by mRNA destabilization (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of mRNA cat abolic process (ortholog); PARTICIPATES IN microRNA pathway; RNA degradation pathway; FOUND IN CCR4-NOT complex (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 10 | 42782042 | 42795207 | Rat | 83 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308536 | Coch | cochlin | ENCODES a protein that exhibits collagen binding (ortholog); INVOLVED IN regulation of cell shape (ortholog); sensory perception of sound (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 9 (ortholog); autosomal recessive nonsyndromic deafness 110 (ortholog); Deafness (ortholog); FOUND IN extracellular matrix (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 6 | 74766485 | 74780504 | Rat | 132 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1311771 | Commd1 | copper metabolism domain containing 1 | ENCODES a protein that exhibits copper ion binding (ortholog); identical protein binding (ortholog); phosphatidic acid binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); copper ion homeostasis (ortholog); Golgi to plasma membrane transport (ortholog); ASSOCIATED WITH allergic diseas e (ortholog); Chronic Hepatitis (ortholog); Copper-Overload Cirrhosis (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 6-propyl-2-thiouracil | 14 | 101081667 | 101185738 | Rat | 150 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303015 | Commd10 | COMM domain containing 10 | INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN nucleoplasm (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 18 | 41927802 | 42061384 | Rat | 77 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307786 | Commd7 | COMM domain containing 7 | ENCODES a protein that exhibits NF-kappaB binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); tumor necrosis factor-mediated signaling pathway (ortholog); FOUND IN protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-pr opyl-2-thiouracil; acrylamide | 3 | 162559762 | 162574543 | Rat | 49 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305402 | Commd8 | COMM domain containing 8 | INVOLVED IN DNA-templated transcription (inferred); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole | 14 | 36403000 | 36413577 | Rat | 59 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307706 | Commd9 | COMM domain containing 9 | INVOLVED IN cholesterol homeostasis (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN nucleoplasm (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; aconitine; aldehydo-D-glucose | 3 | 108630903 | 108645427 | Rat | 58 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310301 | Cops5 | COP9 signalosome subunit 5 | ENCODES a protein that exhibits enzyme binding (ortholog); macrophage migration inhibitory factor binding (ortholog); metal-dependent deubiquitinase activity (ortholog); INVOLVED IN exosomal secretion (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of apoptotic p rocess (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Experimental Liver Neoplasms; hepatocellular carcinoma (ortholog); Stevens-Johnson syndrome (ortholog); FOUND IN chromatin (ortholog); COP9 signalosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 5 | 13975198 | 13993391 | Rat | 128 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307939 | Cpne8 | copine 8 | ENCODES a protein that exhibits calcium-dependent phospholipid binding (inferred); metal ion binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 7 | 123494864 | 123669060 | Rat | 126 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308831 | Creb3 | cAMP responsive element binding protein 3 | ENCODES a protein that exhibits cAMP response element binding protein binding (ortholog); CCR1 chemokine receptor binding (ortholog); chromatin binding (ortholog); INVOLVED IN DNA-templated transcription (ortholog); endoplasmic reticulum unfolded protein response (ortholog); induction of positive ch emotaxis (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 62613652 | 62619019 | Rat | 153 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306804 | Creg1 | cellular repressor of E1A-stimulated genes 1 | ENCODES a protein that exhibits insulin-like growth factor receptor binding (ortholog); INVOLVED IN autophagy (ortholog); endocytosis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH COVID-19 (ortholog); diastolic heart failure (ortholog); Prostatic Neoplasms (ortholog); FOUND I N endosome (ortholog); extracellular space (ortholog); lysosome (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 13 | 80552779 | 80565272 | Rat | 172 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564813 | Crispld1 | cysteine-rich secretory protein LCCL domain containing 1 | INVOLVED IN face morphogenesis (ortholog); hematopoietic stem cell homeostasis (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A | 5 | 6050970 | 6098265 | Rat | 66 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307618 | Csgalnact1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | ENCODES a protein that exhibits acetylgalactosaminyltransferase activity (ortholog); glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity (ortholog); glucuronosyltransferase activity (ortholog); INVOLVED IN cartilage development (ortholog); chondroitin s ulfate proteoglycan biosynthetic process (ortholog); chondroitin sulfate proteoglycan metabolic process (ortholog); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 25761946 | 26097306 | Rat | 131 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306882 | Csnk2a2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cerebral cortex development; liver regeneration; spermatogenesis; PARTICIPATES IN E-cadherin signaling pathway; mitochondrial autophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle; chromatin; nucleus (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole | 19 | 9562340 | 9602136 | Rat | 172 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305629 | Ctdsp1 | CTD small phosphatase 1 | ENCODES a protein that exhibits RNA polymerase II CTD heptapeptide repeat phosphatase activity (ortholog); INVOLVED IN negative regulation of G1/S transition of mitotic cell cycle (ortholog); negative regulation of neurogenesis (ortholog); negative regulation of neuron differentiation (ortholog); PA RTICIPATES IN Bone morphogenetic proteins signaling pathway; RNA polymerase II transcription pathway; ASSOCIATED WITH cerebrotendinous xanthomatosis (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 9 | 83422755 | 83428411 | Rat | 125 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359485 | Ctnna1 | catenin alpha 1 | ENCODES a protein that exhibits beta-catenin binding; protein-containing complex binding; actin filament binding (ortholog); INVOLVED IN axon regeneration; gap junction assembly; male gonad development; PARTICIPATES IN E-cadherin signaling pathway; N-cadherin signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH esophageal cancer; lung carcinoma; acute myeloid leukemia (ortholog); FOUND IN acrosomal vesicle; adherens junction; cell-cell junction; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 18 | 27002330 | 27135009 | Rat | 277 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562749 | Ctnnbip1 | catenin, beta-interacting protein 1 | ENCODES a protein that exhibits armadillo repeat domain binding (ortholog); beta-catenin binding (ortholog); transcription coactivator binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); canonical Wnt signa ling pathway (ortholog); PARTICIPATES IN Wnt signaling pathway; FOUND IN beta-catenin destruction complex (ortholog); beta-catenin-ICAT complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 5 | 165245019 | 165293994 | Rat | 142 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311060 | Ctps1 | CTP synthase 1 | ENCODES a protein that exhibits CTP synthase activity (ortholog); histone H1N76/N77 asparagine deamidase activity (ortholog); identical protein binding (ortholog); INVOLVED IN B cell proliferation (ortholog); CTP biosynthetic process (ortholog); DNA repair-dependent chromatin remodeling (ortholog); PARTICIPATES IN beta-ureidopropionase deficiency pathway; de novo pyrimidine biosynthetic pathway; dihydropyrimidinase deficiency pathway; ASSOCIATED WITH biliary tract benign neoplasm (ortholog); immunodeficiency 24 (ortholog); Nasopharyngeal Neoplasms (ortholog); FOUND IN chromatin (ortholog); cytoophidium (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 3-chloropropane-1,2-diol | 5 | 139372349 | 139440441 | Rat | 206 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309070 | Ctsa | cathepsin A | ENCODES a protein that exhibits carboxypeptidase activity (ortholog); serine-type carboxypeptidase activity (ortholog); INVOLVED IN negative regulation of chaperone-mediated autophagy (ortholog); proteolysis (ortholog); regulation of protein stability (ortholog); PARTICIPATES IN renin-angiotensin ca scade pathway; ASSOCIATED WITH Brain Small Vessel Disease 6 (ortholog); Desbuquois dysplasia (ortholog); galactosialidosis (ortholog); FOUND IN lysosome (ortholog); INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 173988443 | 173994320 | Rat | 162 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562210 | Ctsrl1 | cathepsin R like 1 | ENCODES a protein that exhibits cysteine-type peptidase activity (inferred); hydrolase activity (inferred); peptidase activity (inferred); INVOLVED IN proteolysis (inferred); FOUND IN extracellular space (inferred); lysosome (inferred) | 17 | 3566769 | 3572274 | Rat | 9 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309354 | Ctsw | cathepsin W | ENCODES a protein that exhibits cysteine-type peptidase activity (inferred); hydrolase activity (inferred); peptidase activity (inferred); INVOLVED IN proteolysis (inferred); FOUND IN endoplasmic reticulum (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorod ibenzodioxine | 1 | 212201904 | 212208028 | Rat | 61 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308157 | Cul1 | cullin 1 | ENCODES a protein that exhibits ubiquitin ligase complex scaffold activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); apoptotic process (ortholog); cell population proliferation (ortholog); PARTICIPATES IN neddylation pathway; Notch si gnaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH Stevens-Johnson syndrome (ortholog); FOUND IN cullin-RING ubiquitin ligase complex (ortholog); nucleus (ortholog); Parkin-FBXW7-Cul1 ubiquitin ligase complex (ortholog); INTERACTS WITH aconitine; bisphenol A; Brodifacoum | 4 | 77551781 | 77634210 | Rat | 150 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563853 | Cul4a | cullin 4A | ENCODES a protein that exhibits ubiquitin ligase complex scaffold activity (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cellular response to UV (ortholog); DNA damage response (ortholog); hemopoiesis (ortholog); PARTICIPATES IN nu cleotide excision repair pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH atrial fibrillation (ortholog); Stevens-Johnson syndrome (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (ortholog); Cul4A-RING E3 ubiquitin ligase complex (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 16 | 83086688 | 83124503 | Rat | 163 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1564256 | Cxcl13 | C-X-C motif chemokine ligand 13 | ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine activity (ortholog); CXCR3 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); B cell chemotaxis (ortholog); B cell chemotaxis acr oss high endothelial venule (ortholog); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH endometriosis (ortholog); Experimental Liver Cirrhosis (ortholog); malignant mesothelioma (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17beta-estradiol | 14 | 13912858 | 13917920 | Rat | 200 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310755 | Cxxc1 | CXXC finger protein 1 | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding; histone H3K4me3 reader activity (ortholog); unmethylated CpG binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); regulation of DNA-templated transcription (ortholog); PARTI CIPATES IN DNA modification pathway; histone modification pathway; FOUND IN histone methyltransferase complex (ortholog); nuclear matrix (ortholog); nuclear speck (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; cadmium dichloride | 18 | 70088407 | 70093786 | Rat | 108 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311866 | Cyp2r1 | cytochrome P450, family 2, subfamily r, polypeptide 1 | ENCODES a protein that exhibits D3 vitamins binding (ortholog); heme binding (ortholog); iron ion binding (ortholog); INVOLVED IN response to cesium ion; response to ionizing radiation; response to metal ion; PARTICIPATES IN steroid biosynthetic pathway; ASSOCIATED WITH Abdominal Obesity (ortholog); autism spectrum disorder (ortholog); brain infarction (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; acetamide | 1 | 178166984 | 178232191 | Rat | 150 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306605 | Cyp46a1 | cytochrome P450, family 46, subfamily a, polypeptide 1 | ENCODES a protein that exhibits cholesterol 24-hydroxylase activity (ortholog); heme binding (ortholog); steroid hydroxylase activity (ortholog); INVOLVED IN cholesterol catabolic process (ortholog); progesterone metabolic process (ortholog); protein localization to membrane raft (ortholog); PARTICI PATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH alcohol use disorder; Alzheimer's disease (ortholog); chronic obstructive pulmonary disease (ortholog); FOUND IN dendrite (ortholog); endoplasmic reticulum membrane (ortholog); postsynapse (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 6 | 133011948 | 133039167 | Rat | 134 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305339 | Dap3 | death associated protein 3 | ENCODES a protein that exhibits GTPase activity (ortholog); structural constituent of ribosome (ortholog); INVOLVED IN apoptotic mitochondrial changes (ortholog); mitochondrial translation (ortholog); PARTICIPATES IN Trail mediated signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Perr ault Syndrome 1 (ortholog); Perrault syndrome 7 (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 2 | 176617151 | 176645293 | Rat | 95 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309610 | Dapl1 | death associated protein-like 1 | INVOLVED IN cell population proliferation (ortholog); gene expression (ortholog); negative regulation of CD8-positive, alpha-beta T cell activation (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 3 | 64369734 | 64389677 | Rat | 60 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308576 | Ddhd1 | DDHD domain containing 1 | ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN positive regulation of mitochondrial fission (ortholog); sperm mitochondrion organization (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); hereditary spastic paraplegia (ortholog); I NTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 21304053 | 21370608 | Rat | 98 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303136 | Ddx19a | DEAD-box helicase 19A | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN positive regulation of apoptotic process; response to zinc ion; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bis(2-ethylhexyl) phthalate | 19 | 55851854 | 55872209 | Rat | 62 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1311758 | Ddx41 | DEAD-box helicase 41 | ENCODES a protein that exhibits DNA binding (ortholog); RNA helicase activity (ortholog); INVOLVED IN cell differentiation (ortholog); cell population proliferation (ortholog); cellular response to interferon-beta (ortholog); ASSOCIATED WITH Acute Erythroleukemia (ortholog); acute myeloid leukemia ( ortholog); aplastic anemia (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 17 | 9108030 | 9113562 | Rat | 102 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562393 | Defb21 | defensin beta 21 | ENCODES a protein that exhibits lipopolysaccharide binding (ortholog); membrane destabilizing activity (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); defense response to Gram-negative bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; lipopolysaccharide; trichloroethene | 3 | 161503090 | 161504507 | Rat | 31 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560097 | Defb23 | defensin beta 23 | INVOLVED IN defense response (inferred); defense response to bacterium (inferred); innate immune response (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; (S)-nicotine (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog) | 3 | 161383615 | 161390685 | Rat | 18 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1559541 | Defb24 | defensin beta 24 | ENCODES a protein that exhibits lipopolysaccharide binding (ortholog); INVOLVED IN innate immune response (ortholog); ASSOCIATED WITH female reproductive system disease (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil; amphet amine | 3 | 161506850 | 161512983 | Rat | 35 | old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564902 | Defb36 | defensin beta 36 | INVOLVED IN defense response (inferred); defense response to bacterium (inferred); innate immune response (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; lipopolysaccharide; orphenadrine | 3 | 161538276 | 161547107 | Rat | 25 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560790 | Defb37 | defensin beta 37 | INVOLVED IN defense response (inferred); defense response to bacterium (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 17beta-estradiol 3-benzoate; bisphenol A; cadmium dichloride | 16 | 77485949 | 77499215 | Rat | 14 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563712 | Defb40 | defensin beta 40 | INVOLVED IN defense response (inferred); defense response to bacterium (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 1,2-dimethylhydrazine; bisphenol A; cadmium dichloride | 16 | 77526834 | 77529918 | Rat | 9 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1564782 | Defb51 | defensin beta 51 | INTERACTS WITH 6-propyl-2-thiouracil; amitrole; cadmium dichloride | 16 | 77273373 | 77277495 | Rat | 6 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565394 | Defb52 | defensin beta 52 | INTERACTS WITH atrazine; cadmium dichloride; N-methyl-4-phenylpyridinium | 16 | 77290591 | 77293067 | Rat | 4 | old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305120 | Dennd2d | DENN domain containing 2D | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 196661465 | 196680505 | Rat | 100 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311835 | Derl1 | derlin 1 | ENCODES a protein that exhibits ATPase binding (ortholog); identical protein binding (ortholog); MHC class I protein binding (ortholog); INVOLVED IN cellular response to misfolded protein (ortholog); cellular response to unfolded protein (ortholog); endoplasmic reticulum unfolded protein response (o rtholog); PARTICIPATES IN amyotrophic lateral sclerosis pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Stevens-Johnson syndrome (ortholog); FOUND IN Derlin-1 retrotranslocation complex (ortholog); Derlin-1-VIMP complex (ortholog); early endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-phenylbutyric acid; aflatoxin B1 | 7 | 91293963 | 91316639 | Rat | 108 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309793 | Det1 | DET1 partner of COP1 E3 ubiquitin ligase | ENCODES a protein that exhibits protein-containing complex binding (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); protein ub iquitination (ortholog); protein-containing complex assembly (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; FOUND IN Cul4-RING E3 ubiquitin ligase complex (ortholog); Cul4A-RING E3 ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-methoxyethanol | 1 | 142159120 | 142175366 | Rat | 82 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309390 | Dgcr6 | DiGeorge syndrome critical region gene 6 | ASSOCIATED WITH DiGeorge syndrome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide | 11 | 96432024 | 96442766 | Rat | 66 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311560 | Dhdds | dehydrodolichyl diphosphate synthase subunit | ENCODES a protein that exhibits ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity (ortholog); prenyltransferase activity (ortholog); INVOLVED IN dolichyl diphosphate biosynthetic process (ortholog); dolichyl monophosphate biosynthetic process (ortholog) ; PARTICIPATES IN terpenoid biosynthetic pathway; ASSOCIATED WITH developmental delay and seizures with or without movement abnormalities (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN dehydrodolichyl diphosphate synthase complex (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH acrylamide; bisphenol A; C60 fullerene | 5 | 151482139 | 151508248 | Rat | 83 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359172 | Dhrs1 | dehydrogenase/reductase 1 | ENCODES a protein that exhibits carbonyl reductase (NADPH) activity (ortholog); oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisan drin B; 17beta-estradiol; 3-chloropropane-1,2-diol | 15 | 33206449 | 33213776 | Rat | 92 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305584 | Dhrs3 | dehydrogenase/reductase 3 | ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (ortholog); all-trans-retinol dehydrogenase (NADP+) activity (ortholog); INVOLVED IN bone morphogenesis (ortholog); cardiac septum morphogenesis (ortholog); negative regulation of retinoic acid receptor signaling pathway (ortholog); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH Craniosynostosis Syndrome, Autosomal Recessive (ortholog); Experimental Liver Cirrhosis (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 5 | 162031853 | 162065655 | Rat | 237 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310885 | Diablo | diablo, IAP-binding mitochondrial protein | INVOLVED IN apoptotic signaling pathway (ortholog); intrinsic apoptotic signaling pathway in response to oxidative stress (ortholog); neuron apoptotic process (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness (ortholog); autosomal dominant nonsyndromic deafness 64 (ortholog); brai n ischemia (ortholog); FOUND IN CD40 receptor complex (ortholog); cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 12 | 38716668 | 38731285 | Rat | 257 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304646 | Dis3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | ENCODES a protein that exhibits 3'-5'-RNA exonuclease activity (ortholog); endonuclease activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN CUT catabolic process (ortholog); RNA catabolic process (ortholog); RNA processing (ortholog); PARTICIPATES IN ribosome biog enesis pathway; RNA degradation pathway; ASSOCIATED WITH multiple myeloma (ortholog); Perlman syndrome (ortholog); FOUND IN cytosol (ortholog); nuclear exosome (RNase complex) (ortholog); nucleolus (ortholog); INTERACTS WITH methamphetamine; paracetamol; tetrachloromethane | 15 | 82231922 | 82258299 | Rat | 101 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311247 | Dlgap5 | DLG associated protein 5 | INVOLVED IN signaling (inferred); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); mitotic spindle (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 23113678 | 23144281 | Rat | 206 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311295 | Dmap1 | DNA methyltransferase 1-associated protein 1 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN response to ethanol; negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of double-strand b reak repair via homologous recombination (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH epilepsy (ortholog); Muscle Hypotonia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); NuA4 histone acetyltransferase complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 5 | 136380211 | 136388229 | Rat | 91 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359563 | Dmrtc1c1 | DMRT-like family C1c1 | INVOLVED IN DNA-templated transcription (inferred); INTERACTS WITH bisphenol A; copper atom; copper(0) | X | 71936907 | 71944116 | Rat | 17 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1311213 | Dnai7 | dynein axonemal intermediate chain 7 | ENCODES a protein that exhibits beta-tubulin binding (ortholog); microtubule binding (ortholog); ASSOCIATED WITH lung cancer (ortholog); Lung Neoplasms (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN axonemal dynein complex (ortholog); cilium (ortholog); cytoplasm (ortholog); INTERACT S WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 179874338 | 179910716 | Rat | 64 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310035 | Dnaja4 | DnaJ heat shock protein family (Hsp40) member A4 | ENCODES a protein that exhibits protein-folding chaperone binding (ortholog); unfolded protein binding (ortholog); INVOLVED IN negative regulation of endothelial cell migration (ortholog); negative regulation of inclusion body assembly (ortholog); positive regulation of gene expression (ortholog); F OUND IN cytosol (ortholog); membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 8 | 63975177 | 63998836 | Rat | 132 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359677 | Dnajb12 | DnaJ heat shock protein family (Hsp40) member B12 | ENCODES a protein that exhibits Hsp70 protein binding (ortholog); INVOLVED IN cellular response to misfolded protein (ortholog); ERAD pathway (ortholog); protein folding (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN endoplasmic reticulum (ortholog); endop lasmic reticulum membrane (ortholog); nuclear membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 28371180 | 28389390 | Rat | 78 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307731 | Dnajc11 | DnaJ heat shock protein family (Hsp40) member C11 | INVOLVED IN cristae formation (ortholog); FOUND IN MICOS complex (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 167724776 | 167770032 | Rat | 70 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310237 | Dnajc18 | DnaJ heat shock protein family (Hsp40) member C18 | FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2-methoxyethanol; acetamide | 18 | 27543438 | 27577535 | Rat | 66 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307426 | Dnajc5g | DnaJ heat shock protein family (Hsp40) member C5 gamma | PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN cytoplasm (inferred); membrane (inferred); INTERACTS WITH bisphenol A; cadmium atom; cadmium dichloride | 6 | 30980051 | 30984218 | Rat | 23 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305009 | Dnajc9 | DnaJ heat shock protein family (Hsp40) member C9 | ENCODES a protein that exhibits heat shock protein binding (ortholog); histone binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN nucleosome assembly (ortholog); positive regulation of ATP-dependent activity (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); ex tracellular space (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 15 | 3970843 | 4003009 | Rat | 129 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307473 | Doc2g | double C2-like domains, gamma | ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN neurotransmitter secretion (inferred); FOUND IN membrane (inferred); presynapse (inferred); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; acetamide; acrylamide | 1 | 210724868 | 210729352 | Rat | 16 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564189 | Dock2 | dedicator of cytokinesis 2 | ENCODES a protein that exhibits GTPase activator activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); T cell receptor binding (ortholog); INVOLVED IN alpha-beta T cell activation (ortholog); alpha-beta T cell proliferation (ortholog); chemotaxis (ortholog); PARTICIPATES IN che mokine mediated signaling pathway; Fc gamma receptor mediated signaling pathway; ASSOCIATED WITH esophagus adenocarcinoma (ortholog); Familial Prostate Cancer (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 19331412 | 19748987 | Rat | 127 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1310084 | Dok4 | docking protein 4 | INVOLVED IN cell surface receptor protein tyrosine kinase signaling pathway (ortholog); nervous system development (ortholog); positive regulation of MAPK cascade (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; aconitine | 19 | 10152511 | 10163182 | Rat | 81 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307867 | Dph5 | diphthamide biosynthesis 5 | ENCODES a protein that exhibits diphthine methyl ester synthase activity (ortholog); INVOLVED IN protein histidyl modification to diphthamide (ortholog); ASSOCIATED WITH neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties (ortholog); FOUND IN cytosol (ortholo g); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 2 | 206489556 | 206540590 | Rat | 86 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304993 | Drg1 | developmentally regulated GTP binding protein 1 | ENCODES a protein that exhibits GTPase activity (ortholog); microtubule binding (ortholog); potassium ion binding (ortholog); INVOLVED IN positive regulation of microtubule polymerization (ortholog); regulation of mitotic spindle assembly (ortholog); ASSOCIATED WITH Contracture (ortholog); Neurodeve lopmental Disorders (ortholog); TAN-ALMURSHEDI SYNDROME (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear body (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amitrole | 14 | 82328320 | 82344416 | Rat | 92 | UniProt , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305079 | Dse | dermatan sulfate epimerase | ENCODES a protein that exhibits chondroitin-glucuronate 5-epimerase activity (ortholog); INVOLVED IN dermatan sulfate proteoglycan biosynthetic process (ortholog); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); Ehlers-Danlos syndrome (ortho log); Ehlers-Danlos syndrome musculocontractural type 2 (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 20 | 26661326 | 26740011 | Rat | 86 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565179 | Dsn1 | DSN1 component of MIS12 kinetochore complex | INVOLVED IN skeletal muscle satellite cell proliferation (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); hepatocellular carcinoma (ortholog); FOUND IN fibrillar center (ortholog); kinetochore (ortholog); MIS12/MIND type complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8- tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 166072775 | 166089029 | Rat | 108 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309138 | Dtd2 | D-aminoacyl-tRNA deacylase 2 | ENCODES a protein that exhibits Ala-tRNA(Thr) deacylase activity (ortholog); D-tyrosyl-tRNA(Tyr) deacylase activity (ortholog); INVOLVED IN aminoacyl-tRNA metabolism involved in translational fidelity (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH (+)-schisandrin B; bisphenol A; flutamide | 6 | 75185496 | 75191774 | Rat | 75 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305612 | Dus2 | dihydrouridine synthase 2 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); FMN binding (ortholog); NADPH binding (ortholog); INVOLVED IN antiviral innate immune response (ortholog); tRNA dihydrouridine synthesis (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-t etrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 19 | 50816306 | 50864559 | Rat | 80 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359712 | Dusp13b | dual specificity phosphatase 13B | ENCODES a protein that exhibits phosphatase activity (ortholog); protein tyrosine/serine/threonine phosphatase activity (ortholog); INVOLVED IN dephosphorylation (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-amino-4,6-dinitrotoluen e | 15 | 2616761 | 2624434 | Rat | 85 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1307415 | Dusp14 | dual specificity phosphatase 14 | ENCODES a protein that exhibits hydrolase activity (inferred); MAP kinase tyrosine/serine/threonine phosphatase activity (inferred); phosphoprotein phosphatase activity (inferred); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH pulmonary tuberculosis (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; all-trans-retinoic acid | 10 | 69433949 | 69463863 | Rat | 118 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305804 | Dusp2 | dual specificity phosphatase 2 | ENCODES a protein that exhibits mitogen-activated protein kinase binding (ortholog); phosphoprotein phosphatase activity (ortholog); INVOLVED IN protein dephosphorylation (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH COVID-19 (ortholog); juvenile rhe umatoid arthritis (ortholog); FOUND IN nuclear membrane (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 3 | 135009636 | 135011821 | Rat | 164 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549755 | Dynlt3 | dynein light chain Tctex-type 3 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN positive regulation of mitotic cell cycle; PARTICIPATES IN mitochondria transport pathway; FOUND IN cytoplasmic dynein complex; kinetochore; mitotic spindle astral microtubule; INTERACTS WITH (+)-schisandrin B; 2,3,7,8 -tetrachlorodibenzodioxine; aflatoxin B1 | X | 16000425 | 16009632 | Rat | 108 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309624 | Eapp | E2F-associated phosphoprotein | INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of transcription elongation by RNA polymerase II (ortholog); FOUND IN nuclear speck (ortholog); nucleoplasm (ortholog); nu cleus (ortholog); INTERACTS WITH bisphenol A; Cuprizon; flutamide | 6 | 77879634 | 77929653 | Rat | 49 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562009 | Edc4 | enhancer of mRNA decapping 4 | INVOLVED IN deadenylation-independent decapping of nuclear-transcribed mRNA (inferred); nervous system development (inferred); PARTICIPATES IN microRNA pathway; RNA degradation pathway; FOUND IN cytoplasmic ribonucleoprotein granule (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS W ITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 19 | 50683924 | 50695916 | Rat | 77 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303074 | Edem2 | ER degradation enhancing alpha-mannosidase like protein 2 | ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); INVOLVED IN endoplasmic reticulum mannose trimming (ortholog); ERAD pathway (ortholog); positive regulation of retrograde protein transport, ER to cytosol (ortholog); PARTICIPATES IN Endoplasmic Retic ulum-associated degradation pathway; ASSOCIATED WITH schizophrenia (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 3 | 164661741 | 164687559 | Rat | 90 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306762 | Eef1akmt1 | EEF1A lysine methyltransferase 1 | ENCODES a protein that exhibits methyltransferase activity (ortholog); protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN peptidyl-lysine methylation (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; bisphenol A | 15 | 35809842 | 35826921 | Rat | 65 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560552 | Eefsec | eukaryotic elongation factor, selenocysteine-tRNA-specific | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); ribonucleoprotein complex binding (ortholog); INVOLVED IN selenocysteine incorporation (ortholog); ASSOCIATED WITH chronic obstructive pulmonary disease (ortholog); infantile cerebral and cerebellar atrophy with post natal progressive microcephaly (ortholog); intellectual disability (ortholog); FOUND IN ribonucleoprotein complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 4 | 122276907 | 122473049 | Rat | 93 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359496 | Efemp2 | EGF-like fibulin extracellular matrix protein 2 | ENCODES a protein that exhibits heparin binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN aorta development (ortholog); aorta smooth muscle tissue morphogenesis (ortholog); artery development (ortholog); ASSOCIATED WITH osteoarthritis; aortic aneurysm (ortholog); aortic d isease (ortholog); FOUND IN basement membrane (ortholog); elastic fiber (ortholog); extracellular matrix (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 1 | 212211057 | 212218739 | Rat | 159 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308966 | Efs | embryonal Fyn-associated substrate | ENCODES a protein that exhibits protein domain specific binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cell adhesion (inferred); ASSOCIATED WITH Crohn's disease (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 32362401 | 32374490 | Rat | 85 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310282 | Ehf | ets homologous factor | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN epithelial cell differentiation (ortholog); positive regulation o f transcription by RNA polymerase II (ortholog); ASSOCIATED WITH abdominal aortic aneurysm; Prostatic Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1 | 3 | 110094770 | 110134991 | Rat | 119 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562702 | Eid1 | EP300 interacting inhibitor of differentiation 1 | ENCODES a protein that exhibits histone acetyltransferase binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN cell differentiation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog ); ASSOCIATED WITH Mesothelioma (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; amitrole | 3 | 133376389 | 133378108 | Rat | 92 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306308 | Eif1 | eukaryotic translation initiation factor 1 | ENCODES a protein that exhibits ribosomal small subunit binding (ortholog); translation initiation factor activity (ortholog); INVOLVED IN positive regulation of mRNA cis splicing, via spliceosome (ortholog); regulation of translational initiation (ortholog); translational initiation (ortholog); PAR TICIPATES IN translation initiation pathway; RNA transport pathway; FOUND IN cytoplasm (ortholog); eukaryotic 43S preinitiation complex (ortholog); eukaryotic 48S preinitiation complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; amitrole | 10 | 85747064 | 85749447 | Rat | 168 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560198 | Eif1ax | eukaryotic translation initiation factor 1A, X-linked | ENCODES a protein that exhibits RNA binding (inferred); translation initiation factor activity (inferred); tRNA binding (inferred); INVOLVED IN ribosome assembly (ortholog); translational initiation (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH multiple myeloma (ortholo g); Neoplasm Metastasis (ortholog); FOUND IN eukaryotic 43S preinitiation complex (ortholog); eukaryotic 48S preinitiation complex (ortholog); multi-eIF complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | X | 39307320 | 39322023 | Rat | 113 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309241 | Eif1b | eukaryotic translation initiation factor 1B | ENCODES a protein that exhibits translation initiation factor activity (inferred); INVOLVED IN translation (inferred); translational initiation (inferred); PARTICIPATES IN RNA transport pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 8 | 129080497 | 129083772 | Rat | 69 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306479 | Eif4b | eukaryotic translation initiation factor 4B | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); PARTICIPATES IN mTOR signaling pathway; translation initiation pathway; RNA transport pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); major depressive disorder (ortholog); FOUND IN dendrite; neuron al cell body; postsynapse; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 7 | 135085259 | 135107054 | Rat | 171 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310585 | Elf2 | E74 like ETS transcription factor 2 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regula tion of DNA-templated transcription (ortholog); regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 2 | 137445787 | 137536512 | Rat | 109 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310504 | Elk4 | ETS transcription factor ELK4 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II ( ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 13 | 46004145 | 46027206 | Rat | 135 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1310763 | Endog | endonuclease G | ENCODES a protein that exhibits DNA nuclease activity; DNA endonuclease activity (ortholog); magnesium ion binding (ortholog); INVOLVED IN cellular response to calcium ion; cellular response to glucose stimulus; cellular response to hypoxia; PARTICIPATES IN apoptotic cell death pathway; ASSOCIATED W ITH brain ischemia; Chemical and Drug Induced Liver Injury; congestive heart failure; FOUND IN perikaryon; perinuclear region of cytoplasm; mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; acetamide | 3 | 33846935 | 33849531 | Rat | 199 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 150341834 | ENSRNOG00000065806 | | | | | | Rat | | old_protein_id | gene, protein_coding |
| 1305306 | Epb42 | erythrocyte membrane protein band 4.2 | ENCODES a protein that exhibits protein-glutamine gamma-glutamyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN cell morphogenesis (ortholog); hemoglobin metabolic process (ortholog); monoatomic ion homeostasis (ortholog); ASSOCIATED WITH genetic disease (ortholog); her editary spherocytosis (ortholog); hereditary spherocytosis type 1 (ortholog); FOUND IN ankyrin-1 complex (ortholog); cortical cytoskeleton (ortholog); membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 3 | 128433460 | 128451683 | Rat | 71 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310912 | Eps8l2 | EPS8 signaling adaptor L2 | ENCODES a protein that exhibits actin binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN positive regulation of ruffle assembly (ortholog); regulation of Rho protein signal transduction (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH autoso mal recessive nonsyndromic deafness 106 (ortholog); Meniere's disease (ortholog); FOUND IN cytosol (ortholog); protein-containing complex (ortholog); ruffle membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 205875825 | 205901109 | Rat | 167 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1559872 | Erich1 | glutamate-rich 1 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; ketamine | 16 | 82203536 | 82271361 | Rat | 59 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307058 | Erlin1 | ER lipid raft associated 1 | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN ERAD pathway (ortholog); negative regulation of cholesterol biosynthetic process (ortholog); negative regulation of fatty acid biosynthetic process (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hereditary spastic parapleg ia (ortholog); hereditary spastic paraplegia 62 (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 1 | 252870356 | 252905681 | Rat | 111 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309176 | Erp44 | endoplasmic reticulum protein 44 | ENCODES a protein that exhibits protein disulfide isomerase activity (ortholog); INVOLVED IN glycoprotein metabolic process (ortholog); protein folding (ortholog); response to endoplasmic reticulum stress (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cell surface (ortholog); e ndoplasmic reticulum lumen (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 5 | 67313245 | 67406207 | Rat | 126 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308218 | Ess2 | ess-2 spliceosome associated protein | INVOLVED IN mRNA splicing, via spliceosome (ortholog); nervous system development (ortholog); ASSOCIATED WITH DiGeorge syndrome (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 11 | 96580185 | 96596673 | Rat | 58 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311034 | Ethe1 | ETHE1, persulfide dioxygenase | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); sulfur dioxygenase activity (ortholog); INVOLVED IN glutathione metabolic process (ortholog); hydrogen sulfide metabolic process (ortholog); ASSOCIATED WITH ethylmalonic encephalopathy (ortholog); gene tic disease (ortholog); Nervous System Malformations (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 89311948 | 89327000 | Rat | 153 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562620 | Etv3l | ETS variant transcription factor 3 like | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); sequence-specific DNA binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); regulation of transcription by RNA polymer ase II (inferred); FOUND IN nucleus (inferred); INTERACTS WITH bisphenol A; vinclozolin; 1,2-dichloroethane (ortholog) | 2 | 175289442 | 175302347 | Rat | 25 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1559537 | Etv6 | ETS variant transcription factor 6 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cell differentiation (ortholog); hematopoietic stem cell proliferation (ortholog); mesenchyma l cell apoptotic process (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); B-lymphoblastic leukemia/lymphoma (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 4 | 168580405 | 168819817 | Rat | 179 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311087 | Exd2 | exonuclease 3'-5' domain containing 2 | ENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog); 3'-5'-DNA exonuclease activity (ortholog); 3'-5'-RNA exonuclease activity (ortholog); INVOLVED IN DNA double-strand break processing (ortholog); double-strand break repair (ortholog); double-strand break repair via homologous rec ombination (ortholog); FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog); site of DNA damage (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 6 | 105847931 | 105881780 | Rat | 75 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307749 | Exoc3l4 | exocyst complex component 3-like 4 | INVOLVED IN exocytosis (inferred); FOUND IN exocyst (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3,3',4,4',5-pentachlorobiphenyl | 6 | 136273857 | 136287877 | Rat | 60 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307684 | Extl2 | exostosin-like glycosyltransferase 2 | ENCODES a protein that exhibits alpha-1,4-N-acetylgalactosaminyltransferase activity (ortholog); glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity (ortholog); glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity (ortholog); INVOLVED IN N-acetylglucosamine metabolic process (ortholog); UDP-N-acetylgalactosamine metabolic process (ortholog); PARTICIPATES IN heparan sulfate biosynthetic pathway; FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 2 | 206607106 | 206631861 | Rat | 91 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560783 | Fam118a | family with sequence similarity 118, member A | ENCODES a protein that exhibits identical protein binding (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 7 | 118032313 | 118058888 | Rat | 61 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1561110 | Fam151b | family with sequence similarity 151, member B | INVOLVED IN photoreceptor cell development (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; amitrole | 2 | 25409382 | 25446225 | Rat | 32 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565393 | Fam170a | family with sequence similarity 170, member A | INVOLVED IN positive regulation of DNA-templated transcription (ortholog); transcription by RNA polymerase II (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH Cuprizon; benzo[a]pyrene (ortholog); chlorpyrifos (ortholog) | 18 | 45707817 | 45712548 | Rat | 19 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1564591 | Fam178b | family with sequence similarity 178, member B | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 9 | 46301734 | 46409571 | Rat | 35 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1564695 | Fam181b | family with sequence similarity 181, member B | INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 156578821 | 156580318 | Rat | 54 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311378 | Fam210b | family with sequence similarity 210, member B | INVOLVED IN cellular response to estradiol stimulus (ortholog); erythrocyte differentiation (ortholog); inflammatory response (ortholog); ASSOCIATED WITH systemic lupus erythematosus (ortholog); FOUND IN membrane (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACT S WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 181536665 | 181546830 | Rat | 134 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305587 | Fam241b | family with sequence similarity 241 member B | FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 20 | 30595082 | 30598007 | Rat | 67 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307897 | Fancm | FA complementation group M | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN interstrand cross-link repair (ortholog); positive regulation of protein monoubiquitination (ortholog); replication fork processing (ortholog); ASSOCIATED WITH aplastic anemia (ortholog); azoospermia (ortholog); Breast Cancer, Familial (ortholog); FOUND IN chromatin (ortholog); FANCM-MHF complex (ortholog); Fanconi anaemia nuclear complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; bisphenol AF | 6 | 88862898 | 88916701 | Rat | 124 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1303210 | Farsb | phenylalanyl-tRNA synthetase subunit beta | ENCODES a protein that exhibits phenylalanine-tRNA ligase activity (ortholog); INVOLVED IN phenylalanyl-tRNA aminoacylation (ortholog); protein heterotetramerization (ortholog); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; ASSOCIATED WITH Aneury sm (ortholog); genetic disease (ortholog); INTERSTITIAL LUNG AND LIVER DISEASE (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); phenylalanine-tRNA ligase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 9 | 87336321 | 87395546 | Rat | 149 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359551 | Fblim1 | filamin binding LIM protein 1 | ENCODES a protein that exhibits filamin binding (ortholog); pre-mRNA intronic binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cell-cell adhesion (ortholog); negative regulation of DNA-templated transcription (ortholog); regulation of alternative mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN integrin mediated signaling pathway; FOUND IN cell junction (ortholog); cell periphery (ortholog); chromatin (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 5 | 159167004 | 159198578 | Rat | 153 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305528 | Fbxl12 | F-box and leucine-rich repeat protein 12 | INVOLVED IN ubiquitin-dependent protein catabolic process (ortholog); FOUND IN cytoplasm (ortholog); ubiquitin ligase complex (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 8 | 27453042 | 27459136 | Rat | 60 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305724 | Fbxl4 | F-box and leucine-rich repeat protein 4 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN autophagy of mitochondrion (ortholog); negative regulation of mitophagy (ortholog); ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial DNA depletion syndrome (ort holog); FOUND IN mitochondrial intermembrane space (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; amitrole | 5 | 40752513 | 40826154 | Rat | 104 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359687 | Fbxl6 | F-box and leucine-rich repeat protein 6 | FOUND IN SCF ubiquitin ligase complex (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 7 | 110140243 | 110143176 | Rat | 53 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306664 | Fbxo22 | F-box protein 22 | INVOLVED IN cellular response to starvation (ortholog); nucleocytoplasmic transport (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Tayoun-Maawali syndrome (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACT S WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; amphetamine | 8 | 64476034 | 64492063 | Rat | 99 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304584 | Fbxo28 | F-box protein 28 | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 100 (ortholog); gast rointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); kinetochore (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; fenvalerate | 13 | 96527667 | 96553138 | Rat | 69 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309405 | Fbxo5 | F-box protein 5 | ENCODES a protein that exhibits anaphase-promoting complex binding (ortholog); molecular function inhibitor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN DNA damage response (ortholog); microtubule polymerization (ortholog); negative regulation of cellular senescence (ortholog) ; FOUND IN cytoplasm (ortholog); meiotic spindle (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 1 | 44601412 | 44607781 | Rat | 217 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310899 | Fcf1 | Fcf1 rRNA-processing protein | INVOLVED IN endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (ortholog); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (ortholog); ribosomal small s ubunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN small-subunit processome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 6 | 110348854 | 110360715 | Rat | 71 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311906 | Fcgbpl1 | Fc fragment of IgG binding protein-like 1 | ASSOCIATED WITH Experimental Diabetes Mellitus; FOUND IN extracellular region (inferred); mucus layer (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',5,5'-tetrachlorobiphenyl | 1 | 92552363 | 92590377 | Rat | 22 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311799 | Fermt2 | FERM domain containing kindlin 2 | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); INVOLVED IN adherens junction maintenance (ortholog); cell adhesion (ortholog); cell-matrix adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); angle-closure glaucoma (ortholog); urinary bladder cancer (ortholog); FOUND IN adherens junction (ortholog); cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 15 | 21162603 | 21257995 | Rat | 236 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311068 | Fezf2 | Fez family zinc finger 2 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN axonal fasciculation (ortholog); cell dedifferentiation (ortholog); cerebral cortex GABAergic interneuron migration (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 15 | 15199045 | 15207982 | Rat | 119 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308870 | Fhip2b | FHF complex subunit HOOK interacting protein 2B | INTERACTS WITH bisphenol A; C60 fullerene; cadmium dichloride | 15 | 52066341 | 52084296 | Rat | 38 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1311375 | Fig4 | FIG4 phosphoinositide 5-phosphatase | ENCODES a protein that exhibits phosphatidylinositol bisphosphate phosphatase activity; phosphatidylinositol-3-phosphate phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity; INVOLVED IN positive regulation of neuron projection development; 1-phosphatidyl-1D-myo-inositol 3,5-b isphosphate metabolic process (ortholog); locomotory behavior (ortholog); PARTICIPATES IN inositol metabolic pathway; phosphoinositide metabolic pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); amyotrophic lateral sclerosis type 11 (ortholog); FOUND IN recycling endosome; endosome membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 46183225 | 46306686 | Rat | 136 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549751 | Fkbp10 | FKBP prolyl isomerase 10 | ENCODES a protein that exhibits FK506 binding (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); INVOLVED IN aorta morphogenesis (ortholog); collagen fibril organization (ortholog); extracellular matrix assembly (ortholog); ASSOCIATED WITH BCARD syndrome (ortholog); Bruck syndrome (ortholog); Bruck Syndrome 1 (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog); mitochondrial intermembrane space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 10 | 85845801 | 85858361 | Rat | 138 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311705 | Fkbp14 | FKBP prolyl isomerase 14 | ENCODES a protein that exhibits calcium ion binding (inferred); isomerase activity (inferred); metal ion binding (inferred); ASSOCIATED WITH congenital contractural arachnodactyly (ortholog); congenital muscular dystrophy (ortholog); Desbuquois dysplasia (ortholog); FOUND IN endoplasmic reticulum (i nferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 4 | 85035840 | 85051917 | Rat | 108 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309155 | Fkbp5 | FKBP prolyl isomerase 5 | ENCODES a protein that exhibits heat shock protein binding (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN response to alcohol; response to cocaine; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); PARTICIPATES IN aldosterone signaling pathway; cortisol signaling pathway; ASSOCIATED WITH alcohol dependence; cocaine abuse; alcohol withdrawal syndrome (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 6458931 | 6577227 | Rat | 333 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309837 | Fli1 | Fli-1 proto-oncogene, ETS transcription factor | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); blood circulation (o rtholog); megakaryocyte development (ortholog); ASSOCIATED WITH Ewing sarcoma (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 8 | 39089526 | 39209511 | Rat | 165 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307590 | Flii | FLII, actin remodeling protein | ENCODES a protein that exhibits actin binding (ortholog); INVOLVED IN sarcomere organization (ortholog); ASSOCIATED WITH Contracture (ortholog); dilated cardiomyopathy (ortholog); Dilated Cardiomyopathy 2J (ortholog); FOUND IN brush border (ortholog); podosome (ortholog); INTERACTS WITH 2,4-dinitrot oluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 10 | 45893566 | 45907547 | Rat | 109 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309385 | Flywch1 | FLYWCH-type zinc finger 1 | ENCODES a protein that exhibits transcription coactivator binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Silver-Russell syndrome (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); pericentric heterochromatin (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine | 10 | 13279232 | 13298955 | Rat | 87 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304570 | Fn3krp | fructosamine-3-kinase-related protein | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); protein-ribulosamine 3-kinase activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of DNA-templated transcription (inferred); regulation of DNA-templa ted transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrachlorobiphenyl; bisphenol A | 10 | 107186695 | 107195419 | Rat | 74 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310679 | Foxs1 | forkhead box S1 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN blood vessel development (ortholog); negative regulation of DNA-t emplated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 3 | 161857264 | 161858548 | Rat | 78 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311315 | Frzb | frizzled-related protein | ENCODES a protein that exhibits Wnt-protein binding (ortholog); INVOLVED IN cochlea morphogenesis (ortholog); convergent extension involved in organogenesis (ortholog); inner ear morphogenesis (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog ); lung non-small cell carcinoma (ortholog); lung squamous cell carcinoma (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 85739162 | 85772168 | Rat | 172 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303047 | Fscn3 | fascin actin-bundling protein 3 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN actin filament organization (inferred); spermatid development (inferred); ASSOCIATED WITH hypospadias (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide | 4 | 58008124 | 58017674 | Rat | 57 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564955 | Fsip2l1 | fibrous sheath-interacting protein 2 like 1 | INTERACTS WITH atrazine | X | 132954669 | 132987253 | Rat | 1 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308864 | Fus | Fus RNA binding protein | ENCODES a protein that exhibits ionotropic glutamate receptor binding; myosin V binding; nuclear estrogen receptor binding; INVOLVED IN cellular response to calcium ion; amyloid fibril formation (ortholog); gene expression (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); amyotro phic lateral sclerosis type 1 (ortholog); amyotrophic lateral sclerosis type 6 (ortholog); FOUND IN dendrite; dendritic spine; dendritic spine head; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 192007011 | 192020887 | Rat | 253 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308713 | Fzr1 | fizzy and cell division cycle 20 related 1 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); lens fiber cell differentiation (ortholog); mitotic G2 DNA damage checkpoint signaling (ortholog); PARTICIPATES IN cell cycle pa thway, mitotic; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 109 (ortholog); Developmental Disabilities (ortholog); FOUND IN nuclear membrane (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 8982765 | 8994689 | Rat | 119 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309571 | G3bp2 | G3BP stress granule assembly factor 2 | ENCODES a protein that exhibits molecular condensate scaffold activity (ortholog); INVOLVED IN protein homooligomerization (ortholog); stress granule assembly (ortholog); FOUND IN cytoplasmic stress granule (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2 ,3,7,8-tetrachlorodibenzodioxine | 14 | 16216684 | 16304828 | Rat | 117 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1560391 | Gabpb1 | GA binding protein transcription factor subunit beta 1 | ENCODES a protein that exhibits transcription cis-regulatory region binding (ortholog); INVOLVED IN mitochondrion organization (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis (4-hydroxyphenyl)ethane; 3',5'-cyclic AMP; bisphenol A | 3 | 134333339 | 134380239 | Rat | 97 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309080 | Gadd45b | growth arrest and DNA-damage-inducible, beta | INVOLVED IN negative regulation of protein kinase activity (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of JNK cascade (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; p38 MAPK signaling pathway; cell cycle pathway, mitotic; ASSOCIATED WITH Arseni c Poisoning (ortholog); COVID-19 (ortholog); skin disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (S)-colchicine; 17alpha-ethynylestradiol; 17beta-estradiol | 7 | 9428689 | 9430991 | Rat | 370 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564991 | Gal3st3 | galactose-3-O-sulfotransferase 3 | ENCODES a protein that exhibits galactose 3-O-sulfotransferase activity (ortholog); INVOLVED IN glycolipid biosynthetic process (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN Golgi cisterna membrane (inferred); membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzo dioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 1 | 212022989 | 212032802 | Rat | 37 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305375 | Galk1 | galactokinase 1 | ENCODES a protein that exhibits ATP binding; galactokinase activity; galactose binding; INVOLVED IN carbohydrate phosphorylation; galactose metabolic process; galactitol metabolic process (ortholog); PARTICIPATES IN galactokinase deficiency pathway; galactose metabolic pathway; galactosemia pathway; ASSOCIATED WITH cataract (ortholog); COVID-19 (ortholog); galactokinase deficiency (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 10 | 101742067 | 101746244 | Rat | 191 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310068 | Galnt14 | polypeptide N-acetylgalactosaminyltransferase 14 | ENCODES a protein that exhibits carbohydrate binding (inferred); glycosyltransferase activity (inferred); metal ion binding (inferred); PARTICIPATES IN O-linked glycan biosynthetic pathway; ASSOCIATED WITH Hydrops Fetalis (ortholog); intestinal volvulus (ortholog); FOUND IN Golgi membrane (inferred) ; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 27507878 | 27724033 | Rat | 74 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306443 | Galnt3 | polypeptide N-acetylgalactosaminyltransferase 3 | ENCODES a protein that exhibits calcium ion binding (ortholog); manganese ion binding (ortholog); polypeptide N-acetylgalactosaminyltransferase activity (ortholog); INVOLVED IN apoptotic process (ortholog); cell maturation (ortholog); chondrocyte development (ortholog); PARTICIPATES IN O-linked glyc an biosynthetic pathway; ASSOCIATED WITH calcinosis (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN Golgi apparatus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 3 | 71150559 | 71187321 | Rat | 168 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310169 | Garin5b | golgi associated RAB2 interactor family member 5B | INVOLVED IN cell morphogenesis (ortholog); flagellated sperm motility (ortholog); penetration of zona pellucida (ortholog); FOUND IN sperm head (ortholog); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); aristolochic acid A (ortholog) | 1 | 78105042 | 78122663 | Rat | 22 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308533 | Gatad2b | GATA zinc finger domain containing 2B | ENCODES a protein that exhibits sequence-specific DNA binding (inferred); zinc ion binding (inferred); INVOLVED IN chromatin remodeling (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); GAND syndrome (ortholog); genetic disease (ortholog); FOUND IN chromosome, telomeric region (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH acetamide; acrylamide; bisphenol A | 2 | 178046192 | 178127633 | Rat | 106 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303198 | Gcnt2 | glucosaminyl (N-acetyl) transferase 2 | ENCODES a protein that exhibits acetylglucosaminyltransferase activity (ortholog); N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity (ortholog); INVOLVED IN glycoprotein biosynthetic process (ortholog); maintenance of lens transparency (ortholog); negative regulation of cell-su bstrate adhesion (ortholog); PARTICIPATES IN lacto-series glycosphingolipid metabolic pathway; ASSOCIATED WITH cataract (ortholog); cataract 13 with adult i phenotype (ortholog); genetic disease (ortholog); FOUND IN Golgi membrane (inferred); membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3,3',5,5'-tetrabromobisphenol A | 17 | 24002592 | 24107339 | Rat | 191 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1304678 | Gdf1 | growth differentiation factor 1 | ENCODES a protein that exhibits N-acyltransferase activity (inferred); sphingosine N-acyltransferase activity (inferred); INVOLVED IN negative regulation of cardiac muscle hypertrophy; endoderm development (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH annular pancreas (ortho log); Cardiomegaly (ortholog); congenital heart disease (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 16 | 19131271 | 19146480 | Rat | 98 | old_protein_id | gene, protein-coding, REVIEWED [RefSeq] |
| 1564178 | Gdf3 | growth differentiation factor 3 | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN endoderm development (ortholog); eye development (ortholog); formation of anatomical boundary (ortholog); ASSOCIATED WITH Camptocormia (ortholog); congenital heart disease (ortholog); Desbuquois dysplasia (ortholog); FOUN D IN cytoplasm (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 4 | 157503547 | 157507923 | Rat | 92 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311198 | Gfod2 | Gfo/Idh/MocA-like oxidoreductase domain containing 2 | ENCODES a protein that exhibits oxidoreductase activity (inferred); INVOLVED IN extracellular matrix organization (ortholog); FOUND IN extracellular matrix (ortholog); INTERACTS WITH bisphenol A; gentamycin; ketamine | 19 | 50508626 | 50556945 | Rat | 55 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307770 | Gga1 | golgi associated, gamma adaptin ear containing, ARF binding protein 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN Golgi to plasma membrane protein transport (ortholog); Golgi to plasma membrane transport (ortholog); intracellular protein localization (ortholog); FOUND IN early endosome (ortholog); Golgi apparatus (ortholog); protein-co ntaining complex (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; cadmium dichloride | 7 | 112316530 | 112332249 | Rat | 87 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562246 | Gins1 | GINS complex subunit 1 | INVOLVED IN DNA replication (ortholog); inner cell mass cell proliferation (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); immunodeficiency 55 (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabr omodiphenyl ether | 3 | 160184920 | 160206334 | Rat | 130 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303263 | Gk2 | glycerol kinase 2 | ENCODES a protein that exhibits ATP binding (inferred); glycerol kinase activity (inferred); kinase activity (inferred); INVOLVED IN flagellated sperm motility (ortholog); sperm mitochondrial sheath assembly (ortholog); spermatogenesis (ortholog); PARTICIPATES IN eicosanoid signaling pathway via per oxisome proliferator-activated receptor gamma; glycerolipid metabolic pathway; FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog); sperm midpiece (ortholog); INTERACTS WITH bisphenol A; malathion; 17alpha-ethynylestradiol (ortholog) | 14 | 12411077 | 12412929 | Rat | 47 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309474 | Glb1l | galactosidase, beta 1-like | ENCODES a protein that exhibits beta-galactosidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN carbohydrate metabolic process (inferred); ASSOCIATED WITH cerebrotendinous xanthomatosis (ortholog); INTERACTS WITH 2,3,7,8-tet rachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 9 | 84141993 | 84154176 | Rat | 55 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563612 | Glcci1 | glucocorticoid induced 1 | INVOLVED IN cellular response to glucose stimulus; ASSOCIATED WITH diabetes mellitus; asthma (ortholog); childhood-onset asthma (ortholog); FOUND IN podocyte foot; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | 4 | 37274271 | 37601898 | Rat | 114 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1305978 | Glipr1 | GLI pathogenesis-related 1 | ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); nephroblastoma (ortholog); FOUND IN extracellular region (inferred); membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 7 | 49373579 | 49399190 | Rat | 159 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359265 | Gmcl1 | germ cell-less 1, spermatogenesis associated | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); FOUND IN nuclear envelope (ortholog); nuclear matrix (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 4 | 120697976 | 120737267 | Rat | 57 | UniProt | gene, protein-coding, REVIEWED [RefSeq] |
| 1311008 | Gmds | GDP-mannose 4, 6-dehydratase | ENCODES a protein that exhibits GDP-mannose 4,6-dehydratase activity (ortholog); identical protein binding (ortholog); NADP+ binding (ortholog); INVOLVED IN 'de novo' GDP-L-fucose biosynthetic process (ortholog); GDP-mannose metabolic process (ortholog); Notch signaling pathway (ortholog); PARTICIPA TES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 17 | 32304029 | 32830708 | Rat | 139 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305006 | Gnl2 | G protein nucleolar 2 | ENCODES a protein that exhibits GTP binding (inferred); nucleotide binding (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 5 | 142577798 | 142603185 | Rat | 81 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305521 | Gnpda2 | glucosamine-6-phosphate deaminase 2 | ENCODES a protein that exhibits glucosamine-6-phosphate deaminase activity (ortholog); INVOLVED IN UDP-N-acetylglucosamine biosynthetic process (ortholog); PARTICIPATES IN amino sugar metabolic pathway; nucleotide sugar metabolic pathway; ASSOCIATED WITH Body Weight (ortholog); obesity (ortholog); I NTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 14 | 38874611 | 38892688 | Rat | 87 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563144 | Gnpnat1 | glucosamine-phosphate N-acetyltransferase 1 | ENCODES a protein that exhibits glucosamine 6-phosphate N-acetyltransferase activity; monosaccharide binding; identical protein binding (ortholog); INVOLVED IN glucosamine metabolic process; liver development; N-acetylglucosamine metabolic process; PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; amino sugar metabolic pathway; french type sialuria pathway; ASSOCIATED WITH Animal Disease Models (ortholog); Desbuquois dysplasia (ortholog); lung adenocarcinoma (ortholog); FOUND IN endoplasmic reticulum-Golgi intermediate compartment (ortholog); Golgi apparatus (ortholog); late endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 15 | 21076129 | 21088526 | Rat | 112 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305877 | Gns | glucosamine (N-acetyl)-6-sulfatase | ENCODES a protein that exhibits glycosaminoglycan binding; N-acetylglucosamine-6-sulfatase activity; sulfate binding; INVOLVED IN keratan sulfate proteoglycan catabolic process; heparan sulfate proteoglycan catabolic process (ortholog); PARTICIPATES IN glycosaminoglycan degradation pathway; ASSOCIAT ED WITH Desbuquois dysplasia (ortholog); genetic disease (ortholog); mucopolysaccharidosis III (ortholog); FOUND IN azurophil granule (ortholog); lysosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol | 7 | 58774625 | 58808650 | Rat | 122 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1303197 | Gpaa1 | glycosylphosphatidylinositol anchor attachment 1 | ENCODES a protein that exhibits GPI anchor binding (ortholog); INVOLVED IN attachment of GPI anchor to protein (ortholog); GPI anchored protein biosynthesis (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH genetic disease (ortholog); Glycosylphosp hatidylinositol Biosynthesis Defect 15 (ortholog); FOUND IN endoplasmic reticulum (ortholog); GPI-anchor transamidase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 7 | 109932556 | 109936139 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308865 | Gpatch2 | G patch domain containing 2 | ENCODES a protein that exhibits nucleic acid binding (inferred); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN nuclear speck (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 13 | 101316413 | 101457109 | Rat | 76 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310804 | Gprc5a | G protein-coupled receptor, class C, group 5, member A | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of epidermal growth factor-activated receptor activity (ortholog); ASSOCIATED WITH rheumatoid arthritis (ortholog); FOUND IN plasma membrane (ortholog); vesicle (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 4 | 169634896 | 169653627 | Rat | 165 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562746 | Gps2 | G protein pathway suppressor 2 | ENCODES a protein that exhibits cyclin binding (ortholog); transcription coactivator activity (ortholog); transcription corepressor activity (ortholog); INVOLVED IN B cell differentiation (ortholog); negative regulation of B cell receptor signaling pathway (ortholog); negative regulation of fat cell differentiation (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 10 | 55136043 | 55139106 | Rat | 96 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306884 | Grap | GRB2-related adaptor protein | INVOLVED IN sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 114 (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 46798423 | 46851524 | Rat | 60 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563391 | Gstm6 | glutathione S-transferase, mu 6 | ENCODES a protein that exhibits glutathione transferase activity (inferred); transferase activity (inferred); INVOLVED IN cellular oxidant detoxification (inferred); PARTICIPATES IN glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; FOUND IN cytoplasm (inferred); I NTERACTS WITH 17beta-estradiol; acrylamide; bisphenol A | 2 | 198267734 | 198272508 | Rat | 22 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308625 | Gtf2a1l | general transcription factor 2A subunit 1 like | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cognition (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; methoxychlor | 6 | 11506362 | 11591622 | Rat | 36 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307434 | Gtf3c6 | general transcription factor 3C subunit 6 | ENCODES a protein that exhibits DNA binding (ortholog); RNA polymerase III general transcription initiation factor activity (ortholog); INVOLVED IN transcription by RNA polymerase III (ortholog); transcription initiation at RNA polymerase III promoter (ortholog); PARTICIPATES IN RNA polymerase III t ranscription pathway; FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; bisphenol A; chlorpyrifos | 20 | 45210906 | 45222888 | Rat | 75 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310791 | Gtsf1 | gametocyte specific factor 1 | ENCODES a protein that exhibits tRNA binding (ortholog); INVOLVED IN piRNA-mediated gene silencing by mRNA destabilization (ortholog); secondary piRNA processing (ortholog); FOUND IN cytoplasm (ortholog); piP-body (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; methimazole | 7 | 136417793 | 136436849 | Rat | 36 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1302979 | Habp2 | hyaluronan binding protein 2 | ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN response to bleomycin; proteolysis (ortholog); ASSOCIATED WITH Neoplasm Metastasis; pulmonary fibrosis; Thyroid Neoplasms; FOUND IN extracellular region (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-e stradiol 3-benzoate | 1 | 265321084 | 265355375 | Rat | 101 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308098 | Hapln3 | hyaluronan and proteoglycan link protein 3 | ENCODES a protein that exhibits hyaluronic acid binding (inferred); INVOLVED IN cell adhesion (inferred); FOUND IN gel phase of interstitial matrix (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 142455828 | 142473877 | Rat | 68 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564524 | Hbe2 | hemoglobin, epsilon 2 | ENCODES a protein that exhibits heme binding (inferred); metal ion binding (inferred); oxygen binding (inferred); INVOLVED IN oxygen transport (inferred); FOUND IN hemoglobin complex (inferred); INTERACTS WITH 1,3-dinitrobenzene; 3,7-dihydropurine-6-thione; 4-amino-2,6-dinitrotoluene | 1 | 167691174 | 167692802 | Rat | 20 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304754 | Hcls1 | hematopoietic cell specific Lyn substrate 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN actin filament organization (ortholog); cellular response to cytokine stimulus (ortholog); ery throcyte differentiation (ortholog); ASSOCIATED WITH rheumatoid arthritis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol | 11 | 77322873 | 77346333 | Rat | 143 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311706 | Hdac11 | histone deacetylase 11 | ENCODES a protein that exhibits histone deacetylase activity, hydrolytic mechanism (ortholog); INVOLVED IN oligodendrocyte development; PARTICIPATES IN histone modification pathway; FOUND IN histone deacetylase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisa ndrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 125203044 | 125224584 | Rat | 102 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304581 | Hebp1 | heme binding protein 1 | ENCODES a protein that exhibits heme binding (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 4 | 169705665 | 169735199 | Rat | 112 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1308293 | Hemk1 | HemK methyltransferase 1, mitochondrial release factors N(5)-glutamine | ENCODES a protein that exhibits peptide chain release factor N(5)-glutamine methyltransferase activity (ortholog); INVOLVED IN methylation (inferred); PARTICIPATES IN histidine metabolic pathway; tyrosine metabolic pathway; FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzo dioxine; 2,4,6-trinitrotoluene; 4-amino-2,6-dinitrotoluene | 8 | 116878317 | 116889342 | Rat | 68 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305697 | Hepacam2 | HEPACAM family member 2 | INVOLVED IN centrosome cycle (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN centrosome (ortholog); Golgi apparatus (ortholog); midbody (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 4 | 32400523 | 32435936 | Rat | 65 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308281 | Hif1an | hypoxia inducible factor 1 subunit alpha inhibitor | ENCODES a protein that exhibits [protein]-asparagine 3-dioxygenase activity (ortholog); ankyrin repeat binding (ortholog); carboxylic acid binding (ortholog); INVOLVED IN negative regulation of Notch signaling pathway (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of myoblast differentiation (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 253368400 | 253385495 | Rat | 113 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309691 | Higd2a | HIG1 hypoxia inducible domain family, member 2A | INVOLVED IN mitochondrial respirasome assembly (ortholog); negative regulation of apoptotic process (ortholog); response to quercetin (ortholog); ASSOCIATED WITH Liver Neoplasms (ortholog); pre-malignant neoplasm (ortholog); FOUND IN mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7 ,8-tetrachlorodibenzodioxine; amphetamine; bis(2-ethylhexyl) phthalate | 17 | 10026961 | 10027885 | Rat | 56 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310195 | Hjv | hemojuvelin BMP co-receptor | ENCODES a protein that exhibits BMP binding (ortholog); BMP receptor activity (ortholog); coreceptor activity (ortholog); INVOLVED IN activin receptor signaling pathway (ortholog); BMP signaling pathway (ortholog); cellular response to BMP stimulus (ortholog); PARTICIPATES IN Bone morphogenetic prot eins signaling pathway; ASSOCIATED WITH cholestasis (ortholog); Experimental Liver Cirrhosis (ortholog); hemochromatosis (ortholog); FOUND IN basolateral plasma membrane; BMP receptor complex (ortholog); cell surface (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 2 | 186754801 | 186758708 | Rat | 151 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1564407 | Hmgb3 | high mobility group box 3 | ENCODES a protein that exhibits DNA binding (ortholog); RNA binding (ortholog); INVOLVED IN negative regulation of B cell differentiation (ortholog); negative regulation of myeloid cell differentiation (ortholog); ASSOCIATED WITH syndromic microphthalmia 13 (ortholog); urinary bladder cancer (orthol og); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol | X | 154341106 | 154346087 | Rat | 130 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1565447 | Hormad2 | HORMA domain containing 2 | INVOLVED IN meiotic cell cycle (ortholog); meiotic sister chromatid cohesion (ortholog); FOUND IN chromosome (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH acetamide; atrazine; bisphenol A | 14 | 83438555 | 83524015 | Rat | 38 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310780 | Hoxb3 | homeo box B3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN angiogenesis (ortholog); anterior/posterior pattern specification (ortholog); cartilage d evelopment (ortholog); ASSOCIATED WITH Diaphragmatic Hernia (ortholog); hereditary breast ovarian cancer syndrome (ortholog); Neoplasm Invasiveness (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 10 | 81786001 | 81810655 | Rat | 115 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560113 | Hoxb4 | homeo box B4 | ENCODES a protein that exhibits DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); bone marrow development (ortholog); cell population proliferation (ortholog); ASSOCIATED WITH hereditary breast ovarian c ancer syndrome (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acetamide | 10 | 81781090 | 81783672 | Rat | 103 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311885 | Hsfy2 | heat shock transcription factor, Y linked 2 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH copper atom; copper(0); aflatoxin B1 (ortholog) | 9 | 65676744 | 65678157 | Rat | 20 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306528 | Hspa4l | heat shock protein family A (Hsp70) member 4 like | ENCODES a protein that exhibits ATP binding; INVOLVED IN protein folding; response to unfolded protein; PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN cytoplasm; nucleus; cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propy l-2-thiouracil | 2 | 125668346 | 125726404 | Rat | 214 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308906 | Htra2 | HtrA serine peptidase 2 | ENCODES a protein that exhibits serine-type peptidase activity; identical protein binding (ortholog); peptidase activity (ortholog); INVOLVED IN neuron apoptotic process; positive regulation of apoptotic process; response to herbicide; PARTICIPATES IN intrinsic apoptotic pathway; Parkinson's disease pathway; ASSOCIATED WITH asphyxia neonatorum; cryptorchidism; middle cerebral artery infarction; FOUND IN CD40 receptor complex (ortholog); chromatin (ortholog); cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; clofibric acid | 4 | 117114631 | 117117793 | Rat | 264 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1566275 | Hyal5 | hyaluronoglucosaminidase 5 | ENCODES a protein that exhibits hyalurononglucosaminidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN carbohydrate metabolic process (inferred); fusion of sperm to egg plasma membrane involved in single fertilization (infer red); single fertilization (inferred); PARTICIPATES IN glycosaminoglycan degradation pathway; FOUND IN acrosomal vesicle (inferred); external side of plasma membrane (inferred); plasma membrane (inferred) | 4 | 54306643 | 54378272 | Rat | 19 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564219 | Hyal6 | hyaluronoglucosaminidase 6 | ENCODES a protein that exhibits hyalurononglucosaminidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN carbohydrate metabolic process (inferred); PARTICIPATES IN glycosaminoglycan degradation pathway; FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A | 4 | 54203635 | 54216332 | Rat | 10 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359660 | Icam2 | intercellular adhesion molecule 2 | ENCODES a protein that exhibits integrin binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN cell adhesion mediated by integrin (ortholog); dendritic cell migration (ortholog); leukocyte cell-cell adhesion (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); malignan t mesothelioma (ortholog); Stomach Neoplasms (ortholog); FOUND IN cell periphery (ortholog); cleavage furrow (ortholog); microvillus (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 91808449 | 91819319 | Rat | 146 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359421 | Ifgga2l1 | interferon-gamma-inducible GTPase 2 like 1 | ENCODES a protein that exhibits GTP binding (inferred); hydrolase activity (inferred); nucleotide binding (inferred); FOUND IN membrane (inferred) | 18 | 56031907 | 56040627 | Rat | 10 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559721 | Ifi27l2a | interferon, alpha-inducible protein 27 like 2A | INVOLVED IN apoptotic process (ortholog); response to virus (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 6 | 128363658 | 128365144 | Rat | 146 | UniProt , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304553 | Ifi35 | interferon-induced protein 35 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN macrophage activation involved in immune response (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of non-canonical NF-kappaB signal transduction (ortholog); ASSOCIATED W ITH Experimental Liver Cirrhosis (ortholog); Human Influenza (ortholog); Spontaneous Abortions (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 10 | 86881270 | 86889523 | Rat | 146 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307804 | Ifit2 | interferon-induced protein with tetratricopeptide repeats 2 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN antiviral innate immune response (ortholog); cellular response to interferon-alpha (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 1 | 241515735 | 241521799 | Rat | 199 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359704 | Ift74 | intraflagellar transport 74 | ENCODES a protein that exhibits beta-tubulin binding (ortholog); chromatin binding (ortholog); INVOLVED IN cilium assembly (ortholog); determination of left/right symmetry (ortholog); epidermis development (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); autism spectrum disord er (ortholog); Bardet-Biedl syndrome (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; bisphenol A | 5 | 114576106 | 114679581 | Rat | 131 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310919 | Igdcc4 | immunoglobulin superfamily, DCC subclass, member 4 | INVOLVED IN negative regulation of neurogenesis (inferred); FOUND IN plasma membrane (inferred); INTERACTS WITH acrylamide; bisphenol A; Cuprizon | 8 | 74517082 | 74552834 | Rat | 90 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305656 | Igfbpl1 | insulin-like growth factor binding protein-like 1 | ENCODES a protein that exhibits insulin-like growth factor binding (inferred); INVOLVED IN cellular response to tumor cell (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; acrylamide | 5 | 64872056 | 64887461 | Rat | 65 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306896 | Igtp | interferon gamma induced GTPase | ENCODES a protein that exhibits GTP binding (inferred); hydrolase activity (inferred); nucleotide binding (inferred); PARTICIPATES IN toxoplasmosis pathway; FOUND IN membrane (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 10 | 42875047 | 42882866 | Rat | 59 | old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1566151 | Il20rb | interleukin 20 receptor subunit beta | ENCODES a protein that exhibits interleukin-20 binding (ortholog); INVOLVED IN homeostasis of number of cells within a tissue (ortholog); immune response-inhibiting signal transduction (ortholog); inflammatory response to antigenic stimulus (ortholog); PARTICIPATES IN cytokine mediated signaling pat hway; Jak-Stat signaling pathway; ASSOCIATED WITH toxic shock syndrome (ortholog); INTERACTS WITH alpha-Zearalanol; bisphenol A; gentamycin | 8 | 109858108 | 109896066 | Rat | 106 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304950 | Il21r | interleukin 21 receptor | ENCODES a protein that exhibits cytokine receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway (inferred); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH atopic dermatitis (ortholog); B-cell lymphoma (ortholog); Behcet's disease (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 189598682 | 189626340 | Rat | 120 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563019 | Il36g | interleukin 36, gamma | ENCODES a protein that exhibits cytokine activity (ortholog); INVOLVED IN negative regulation of myoblast differentiation (ortholog); negative regulation of myoblast fusion (ortholog); positive regulation of cytokine production (ortholog); FOUND IN cytosol (ortholog); extracellular space (ortholog); INTERACTS WITH bisphenol A; paracetamol; sodium fluoride | 3 | 27346675 | 27352839 | Rat | 74 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307347 | Ing2 | inhibitor of growth family, member 2 | ENCODES a protein that exhibits DNA binding (ortholog); histone H3K4me3 reader activity (ortholog); phosphatidylinositol binding (ortholog); INVOLVED IN flagellated sperm motility (ortholog); male germ-line stem cell asymmetric division (ortholog); male meiosis I (ortholog); PARTICIPATES IN histone modification pathway; FOUND IN CCAAT-binding factor complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 16 | 51305311 | 51316177 | Rat | 85 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307908 | Ing5 | inhibitor of growth family, member 5 | ENCODES a protein that exhibits chromatin binding (ortholog); histone H3K4me3 reader activity (ortholog); INVOLVED IN DNA replication-dependent chromatin disassembly (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of growth (ortholog); FOUND IN histon e acetyltransferase complex (ortholog); MOZ/MORF histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; cadmium atom; cadmium dichloride | 9 | 101772845 | 101793734 | Rat | 118 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1562258 | Ino80b | INO80 complex subunit B | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 complex (ortholog); nuclear body (ortholog); nucleolus (ortholo g); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 4 | 117185427 | 117188930 | Rat | 89 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306071 | Inpp1 | inositol polyphosphate-1-phosphatase | ENCODES a protein that exhibits hydrolase activity (inferred); inositol-1,4-bisphosphate 1-phosphatase activity (inferred); metal ion binding (inferred); INVOLVED IN phosphatidylinositol phosphate biosynthetic process (inferred); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabol ic pathway; phosphatidylinositol 3-kinase signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); cleft palate (ortholog); retinal disease (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acetamide | 9 | 56161816 | 56209774 | Rat | 100 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1549774 | Irf3 | interferon regulatory factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to exogenous dsRNA; positive regulation of canonical NF-kappaB signal transduction; positive regulation of cytokine production; PARTICIPATES IN Toll-like receptor signaling pathway; hepatitis C pathway; influenza A pathway; ASSOCIATED WITH asthma (ortholog); bacterial pneumonia (ortholog); Herpes Simplex Encephalitis (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 1 | 104616608 | 104621402 | Rat | 275 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312024 | Irf8 | interferon regulatory factor 8 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to type II interferon; positive regulation of a poptotic process; cellular response to lipopolysaccharide (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH B-lymphoblastic leukemia/lymphoma (ortholog); Behcet's disease (ortholog); cardiomyopathy (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acetamide | 19 | 65699284 | 65721066 | Rat | 235 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305581 | Itgb2 | integrin subunit beta 2 | ENCODES a protein that exhibits cell adhesion molecule binding; protein-containing complex binding; amyloid-beta binding (ortholog); INVOLVED IN cell-cell adhesion; cellular extravasation; endothelial cell migration; PARTICIPATES IN hypoxia inducible factor pathway; integrin mediated signaling pathw ay; Entamoebiasis pathway; ASSOCIATED WITH Acute Lung Injury; allergic rhinitis; Experimental Arthritis; FOUND IN cell surface; external side of plasma membrane (ortholog); integrin alphaD-beta2 complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 20 | 11061009 | 11097242 | Rat | 421 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1306099 | Itih1 | inter-alpha trypsin inhibitor, heavy chain 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); hyaluronic acid binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); Liver Neoplasms (ortholog); Osteoarthritis, Hip (ortholog); FOUND IN extracellular matrix (ortho log); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 16 | 6128696 | 6142813 | Rat | 129 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1559423 | Itm2a | integral membrane protein 2A | INVOLVED IN plasma cell differentiation (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | X | 76559183 | 76565144 | Rat | 116 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359526 | Ka11 | type I keratin KA11 | ENCODES a protein that exhibits structural molecule activity (inferred); FOUND IN cytoplasm (inferred); intermediate filament (inferred); nucleus (inferred); INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; bisphenol A | 10 | 85661820 | 85667785 | Rat | 15 | UniProt , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308853 | Kank3 | KN motif and ankyrin repeat domains 3 | INVOLVED IN negative regulation of actin filament polymerization (inferred); podocyte cell migration (inferred); regulation of Rho protein signal transduction (inferred); ASSOCIATED WITH COVID-19 (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; ammonium ch loride | 7 | 15296538 | 15309838 | Rat | 82 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311256 | Katnb1 | katanin regulatory subunit B1 | ENCODES a protein that exhibits ATPase regulator activity (ortholog); dynein complex binding (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN microtubule severing; positive regulation of apoptotic process; positive regulation of neuron projection development; ASSOCIATED WITH g enetic disease (ortholog); lissencephaly 6 (ortholog); FOUND IN axon; growth cone; midbody; INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol | 19 | 9927249 | 9946750 | Rat | 113 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1310698 | Kazald1 | Kazal-type serine peptidase inhibitor domain 1 | ENCODES a protein that exhibits insulin-like growth factor binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); FOUND IN extracellular matrix (ortholog); interstitial matrix (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 6-propyl-2-thiouracil | 1 | 253888639 | 253892211 | Rat | 90 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307695 | Kif20a | kinesin family member 20A | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN microtubule bundle formation (ortholog); midbody abscission (ortholog); mitotic cytokinesis (ortholog); ASSOCIATED WITH COVID-19 (ortholog); familial restrictive cardiomyopathy 6 (ortholog); hepatocellular carcinoma (orth olog); FOUND IN midbody (ortholog); mitotic spindle (ortholog); spindle (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 18 | 26504422 | 26512908 | Rat | 293 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307693 | Kifc3 | kinesin family member C3 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN epithelial cell-cell adhesion (ortholog); Golgi organization (ortholog); microtubule-based process (ortholog); PARTICIPATES IN E-cadherin signaling pathway; FOUND IN centrosome (ortholog); Golgi apparatus (ortholog); k inesin complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 9831159 | 9926405 | Rat | 127 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307377 | Klc2 | kinesin light chain 2 | ENCODES a protein that exhibits kinesin binding (ortholog); INVOLVED IN axo-dendritic transport (ortholog); lysosome localization (ortholog); ASSOCIATED WITH nonsyndromic deafness (ortholog); SPOAN syndrome (ortholog); FOUND IN ciliary rootlet (ortholog); cytoplasm (ortholog); cytosol (ortholog); IN TERACTS WITH (S)-AMPA; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 211843927 | 211854160 | Rat | 96 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303228 | Klk4 | kallikrein-related peptidase 4 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); peptidase activity (inferred); INVOLVED IN amelogenesis (ortholog); enamel mineralization (ortholog); extracellular matrix disassembly (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogen esis imperfecta type 2A1 (ortholog); breast cancer (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; Cuprizon; genistein | 1 | 103480731 | 103485963 | Rat | 61 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1359667 | Klra2 | killer cell lectin-like receptor, subfamily A, member 2 | ENCODES a protein that exhibits carbohydrate binding (inferred); INVOLVED IN cell adhesion (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 166604723 | 166717294 | Rat | 14 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309641 | Kmt2e | lysine methyltransferase 2E | ENCODES a protein that exhibits enzyme binding (ortholog); histone H3 methyltransferase activity (ortholog); histone H3K4me3 reader activity (ortholog); INVOLVED IN epigenetic regulation of gene expression (ortholog); erythrocyte differentiation (ortholog); neutrophil activation (ortholog); PARTICIP ATES IN histone modification pathway; lysine degradation pathway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); euchromatin (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 12550570 | 12655329 | Rat | 151 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359376 | Kng1 | kininogen 1 | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (ortholog); hormone activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN negative regulation of blood coagulation (ortholog); negative regulation of cell adhesion (ortholog); negative regulation of prot eolysis (ortholog); PARTICIPATES IN kallikrein-kinin cascade pathway; kinin signaling pathway; syndecan signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm; Kininogen Deficiency, High Molecular Weight and Low Molecular Weight; acquired angioedema (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 1-octadec-9-enoylglycero-3-phosphate | 11 | 91317354 | 91340148 | Rat | 303 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311483 | Kpna4 | karyopherin subunit alpha 4 | ENCODES a protein that exhibits nuclear import signal receptor activity (ortholog); nuclear localization sequence binding (ortholog); INVOLVED IN NLS-bearing protein import into nucleus (ortholog); protein import into nucleus (ortholog); response to hydrogen peroxide (ortholog); FOUND IN cytoplasm ( ortholog); nuclear pore (ortholog); nucleoplasm (ortholog); INTERACTS WITH 3,4-methylenedioxymethamphetamine; bisphenol A; cadmium dichloride | 2 | 155635679 | 155691056 | Rat | 135 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310341 | Kptn | kaptin (actin binding protein) | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to glucose starvation (ortholog); negative regulation of TORC1 signaling (ortholog); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 41 (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN filamentous actin (ortholog); KICSTOR complex (ortholog); lamellipodium (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; cadmium dichloride | 1 | 85936922 | 85937716 | Rat | 41 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1306183 | Krr1 | KRR1 small subunit processome component | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); small-subunit processome (ortholog); INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; bisphenol A | 7 | 49361794 | 49374222 | Rat | 82 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305300 | Krt35 | keratin 35 | ENCODES a protein that exhibits structural molecule activity (inferred); FOUND IN intermediate filament (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 10 | 85526571 | 85529968 | Rat | 27 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303149 | Krt85 | keratin 85 | ASSOCIATED WITH ectodermal dysplasia 4 (ortholog); FOUND IN intermediate filament (inferred); keratin filament (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 7 | 134508913 | 134515786 | Rat | 43 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1303215 | Krt86 | keratin 86 | ASSOCIATED WITH genetic disease (ortholog); hair disease (ortholog); monilethrix (ortholog); FOUND IN keratin filament (ortholog); INTERACTS WITH alpha-Zearalanol; bis(2-ethylhexyl) phthalate; bisphenol A | 7 | 134470224 | 134476873 | Rat | 57 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1310809 | Lancl2 | LanC like glutathione S-transferase 2 | ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylinositol-5-phosphate binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of abscisic ac id-activated signaling pathway (ortholog); FOUND IN cortical actin cytoskeleton (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 4 | 88771974 | 88813920 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310787 | Lao1 | L-amino acid oxidase 1 | ENCODES a protein that exhibits L-amino-acid oxidase activity (inferred); oxidoreductase activity (inferred); toxin activity (inferred); INVOLVED IN defense response to bacterium (inferred); modulation of process of another organism (inferred); PARTICIPATES IN alanine, aspartate and glutamate metabo lic pathway; cysteine and methionine metabolic pathway; phenylalanine metabolic pathway; FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; fenvalerate | 5 | 137859033 | 137868926 | Rat | 19 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307509 | Larp1b | La ribonucleoprotein 1B | ENCODES a protein that exhibits RNA binding (inferred); ASSOCIATED WITH prostate cancer (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 2 | 125860935 | 125897189 | Rat | 112 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1565755 | Las1l | LAS1-like, ribosome biogenesis factor | ENCODES a protein that exhibits endonuclease activity (inferred); INVOLVED IN rRNA processing (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN MLL1 complex (ortholog); nucleolus (ortholog); nucleus (ortholog) ; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide | X | 64861472 | 64883221 | Rat | 79 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306747 | Lcn8 | lipocalin 8 | ENCODES a protein that exhibits small molecule binding (inferred); INVOLVED IN response to hormone (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 3,4-methylenedioxymethamphetamine; acrylamide; bisphenol A | 3 | 28866061 | 28869045 | Rat | 24 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306341 | Lcn9 | lipocalin 9 | ENCODES a protein that exhibits small molecule binding (inferred); ASSOCIATED WITH Ehlers-Danlos syndrome classic type 1 (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; cadmium dichloride; trichloroethene | 3 | 29041710 | 29050677 | Rat | 14 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308288 | Lcp1 | lymphocyte cytosolic protein 1 | ENCODES a protein that exhibits actin filament binding (ortholog); GTPase binding (ortholog); identical protein binding (ortholog); INVOLVED IN animal organ regeneration; actin filament bundle assembly (ortholog); cell migration (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); Experimental Liver Cirrhosis (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); actin filament (ortholog); actin filament bundle (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 15 | 56846375 | 56954090 | Rat | 213 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307414 | Lgalsl | galectin-like | ENCODES a protein that exhibits carbohydrate binding (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 99198340 | 99205846 | Rat | 115 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310391 | Lgi2 | leucine-rich repeat LGI family, member 2 | INVOLVED IN inhibitory synapse assembly (ortholog); ASSOCIATED WITH epilepsy (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 14 | 62628746 | 62656231 | Rat | 65 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309875 | Lig3 | DNA ligase 3 | ENCODES a protein that exhibits DNA ligase activity; DNA ligase (ATP) activity (ortholog); INVOLVED IN base-excision repair (ortholog); double-strand break repair (ortholog); double-strand break repair via alternative nonhomologous end joining (ortholog); PARTICIPATES IN nucleotide excision repair p athway; base excision repair pathway; ASSOCIATED WITH middle cerebral artery infarction; Cardiac Arrhythmias (ortholog); genetic disease (ortholog); FOUND IN condensed nuclear chromosome (ortholog); DNA ligase III-XRCC1 complex (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4-hydroperoxycyclophosphamide | 10 | 68215371 | 68238705 | Rat | 179 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560732 | Lims1 | LIM zinc finger domain containing 1 | ENCODES a protein that exhibits protein-containing complex binding; protein kinase binding (ortholog); zinc ion binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); actin filament network formation (ortholog); cell-cell adhesion (ortholog); PARTICIPATES IN integrin mediated sig naling pathway; FOUND IN protein-containing complex; cell-cell junction (ortholog); focal adhesion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 20 | 26851364 | 26961607 | Rat | 155 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560307 | Llgl2 | LLGL scribble cell polarity complex component 2 | ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN branching involved in labyrinthine layer morphogenesis (ortholog); establishment or maintenance of polarity of embryonic epithelium (ortholog); L-leucine transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); COVI D-19 (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; bisphenol A | 10 | 101549911 | 101585466 | Rat | 121 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308261 | Llph | LLP homolog, long-term synaptic facilitation factor | ENCODES a protein that exhibits basal RNA polymerase II transcription machinery binding (ortholog); INVOLVED IN dendrite extension (ortholog); positive regulation of dendritic spine development (ortholog); FOUND IN chromosome (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenz odioxine; bisphenol A; paracetamol | 7 | 57620925 | 57625924 | Rat | 64 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308965 | Lman2 | lectin, mannose-binding 2 | ENCODES a protein that exhibits carbohydrate binding (ortholog); D-mannose binding (ortholog); heat shock protein binding (ortholog); INVOLVED IN positive regulation of phagocytosis (ortholog); retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (ortholog); PARTICIPATES IN Endoplas mic Reticulum-associated degradation pathway; FOUND IN cell surface (ortholog); COPI-coated vesicle (ortholog); cytoplasmic vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan | 17 | 9274362 | 9294950 | Rat | 100 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311393 | Lman2l | lectin, mannose-binding 2-like | ENCODES a protein that exhibits carbohydrate binding (inferred); metal ion binding (inferred); INVOLVED IN protein transport (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 69 (ortholog); autosomal recessive intellectual developmental disorder 52 (ortholog); bipola r disorder (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH bisphenol A; leflunomide; thioacetamide | 9 | 46157596 | 46181151 | Rat | 79 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1305670 | Lmo4 | LIM domain only 4 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN motor neuron axon guidance (ortholog); negative regulation of protein-containing complex assembly (ortholog); negative regulation of transcription by RNA po lymerase II (ortholog); PARTICIPATES IN interleukin-6 signaling pathway; ASSOCIATED WITH anencephaly (ortholog); FOUND IN cell leading edge (ortholog); nucleus (ortholog); RNA polymerase II transcription regulator complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-sulfonyldiphenol | 2 | 235924574 | 235941609 | Rat | 164 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312042 | Lnpk | lunapark, ER junction formation factor | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN blood coagulation (ortholog); embryonic digit morphogenesis (ortholog); embryonic forelimb morphogenesis (ortholog); ASSOCIATED WITH genetic disease (ortholog); NEURODEVELOPMENTAL DISORDER WITH EPILEPSY AND HYPOPLASIA OF THE CORPUS CALLOSUM (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); endoplasmic reticulum tubular network membrane (ortholog); INTERACTS WITH alpha-Zearalanol; bisphenol A; cobalt dichloride | 3 | 79826318 | 79894514 | Rat | 84 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308159 | Lnx1 | ligand of numb-protein X 1 | ENCODES a protein that exhibits identical protein binding (ortholog); PDZ domain binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN synapse maturation (ortholog); ubiquitin-dependent protein catabolic process (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCI ATED WITH head and neck squamous cell carcinoma (ortholog); FOUND IN cell junction (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 14 | 33868517 | 33971217 | Rat | 115 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 151664697 | LOC124459649 | killer cell lectin-like receptor subfamily A, member 12-like | ENCODES a protein that exhibits carbohydrate binding (inferred); INVOLVED IN cell adhesion (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 4 | 165200589 | 165252165 | Rat | 4 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1305466 | Lonp2 | lon peptidase 2, peroxisomal | ENCODES a protein that exhibits enzyme binding (ortholog); peptidase activity (ortholog); protease binding (ortholog); INVOLVED IN protein processing (ortholog); protein targeting to peroxisome (ortholog); regulation of fatty acid beta-oxidation (ortholog); ASSOCIATED WITH prostate cancer (ortholog) ; FOUND IN peroxisomal matrix; peroxisome; cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 36580736 | 36672242 | Rat | 132 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1307646 | Lpin1 | lipin 1 | ENCODES a protein that exhibits histone deacetylase binding (ortholog); peroxisome proliferator activated receptor binding (ortholog); phosphatidate phosphatase activity (ortholog); INVOLVED IN animal organ regeneration; cellular response to insulin stimulus; negative regulation of myelination; PART ICIPATES IN mTOR signaling pathway; ASSOCIATED WITH abnormal sciatic nerve morphology; dysmyelination; increased cell proliferation; ASSOCIATED WITH Cachexia; end stage renal disease; Experimental Diabetes Mellitus; FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 6 | 45039110 | 45145845 | Rat | 306 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310471 | Lrp10 | LDL receptor related protein 10 | ENCODES a protein that exhibits low-density lipoprotein particle receptor activity (ortholog); INVOLVED IN inner ear development (ortholog); lipid metabolic process (ortholog); lipid transport (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); bladder exstrophy-epispadias-cloacal exstr ophy complex (ortholog); Macrocephaly (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 15 | 31891358 | 31897530 | Rat | 111 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560165 | Lrrc17 | leucine rich repeat containing 17 | INVOLVED IN bone marrow development (ortholog); negative regulation of osteoclast differentiation (ortholog); osteoblast differentiation (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil | 4 | 14393632 | 14424048 | Rat | 106 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311716 | Lrrc2 | leucine rich repeat containing 2 | INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 8 | 119814514 | 119847587 | Rat | 63 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308720 | Lrrc24 | leucine rich repeat containing 24 | INVOLVED IN positive regulation of synapse assembly (ortholog); INTERACTS WITH acrylamide; atrazine; bisphenol A | 7 | 110317935 | 110325201 | Rat | 44 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1561461 | Lrrc43 | leucine rich repeat containing 43 | ASSOCIATED WITH COVID-19 (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; bisphenol A | 12 | 38735033 | 38753143 | Rat | 32 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309466 | Lrrc49 | leucine rich repeat containing 49 | FOUND IN centriolar satellite (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 8 | 69948962 | 70056579 | Rat | 53 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1312014 | Lrrc52 | leucine rich repeat containing 52 | ENCODES a protein that exhibits potassium channel activator activity (ortholog); potassium channel activity (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN positive regulation of voltage-gated potassium channel activity (ortholog); potassium ion transmembrane transport (ortholo g); potassium ion transport (ortholog); FOUND IN voltage-gated potassium channel complex (ortholog); INTERACTS WITH bisphenol A; furan; genistein | 13 | 82130174 | 82153569 | Rat | 26 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565523 | Lsm11 | LSM11, U7 small nuclear RNA associated | ENCODES a protein that exhibits U7 snRNA binding (ortholog); INVOLVED IN mRNA 3'-end processing by stem-loop binding and cleavage (ortholog); positive regulation of G1/S transition of mitotic cell cycle (ortholog); regulation of chromatin organization (ortholog); ASSOCIATED WITH Aicardi-Goutieres Sy ndrome 8 (ortholog); FOUND IN histone pre-mRNA 3'end processing complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17alpha-ethynylestradiol | 10 | 30869168 | 30887275 | Rat | 106 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305695 | Lsm14a | LSM14A mRNA processing body assembly factor | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); double-stranded RNA binding (ortholog); single-stranded RNA binding (ortholog); INVOLVED IN defense response to virus (ortholog); mitotic spindle assembly (ortholog); negative regulation of translation (ortholog); FOUND IN cytop lasm (ortholog); cytoplasmic ribonucleoprotein granule (ortholog); cytoplasmic stress granule (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 96101990 | 96146578 | Rat | 97 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306133 | Lsp1 | lymphocyte-specific protein 1 | ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN cellular response to interleukin-7 (ortholog); chemotaxis (ortholog); defense response (ortholog); PARTICIPATES IN tuberculosis pathway; ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); calcinosis (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 207044157 | 207077891 | Rat | 153 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303162 | Ltb | lymphotoxin beta | ENCODES a protein that exhibits cytokine activity (inferred); tumor necrosis factor binding (inferred); tumor necrosis factor receptor binding (inferred); INVOLVED IN gene expression (ortholog); lymph node development (ortholog); positive regulation of interleukin-12 production (ortholog); PARTICIPA TES IN cytokine mediated signaling pathway; rheumatoid arthritis pathway; ASSOCIATED WITH contact dermatitis (ortholog); cutaneous leishmaniasis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 3632209 | 3634054 | Rat | 189 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309448 | Ltbr | lymphotoxin beta receptor | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); myeloid dendritic cell differentiation (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortho log); PARTICIPATES IN cytokine mediated signaling pathway; tuberculosis pathway; ASSOCIATED WITH autosomal recessive pseudohypoaldosteronism type 1 (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); malaria (ortholog); FOUND IN Golgi apparatus (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 159795115 | 159801571 | Rat | 137 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359487 | Ly49si1 | immunoreceptor Ly49si1 | INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 165272974 | 165286574 | Rat | 9 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1359240 | Ly49si2 | immunoreceptor Ly49si2 | ENCODES a protein that exhibits carbohydrate binding (inferred); INVOLVED IN cell adhesion (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine | 4 | 165358092 | 165410591 | Rat | 15 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1565410 | Ly6cl1 | Ly6-C antigen like 1 | FOUND IN plasma membrane (inferred); side of membrane (inferred); synapse (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 109002958 | 109097841 | Rat | 15 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303112 | Ly6g6e | lymphocyte antigen 6 family member G6E | ENCODES a protein that exhibits acetylcholine receptor activator activity (ortholog); acetylcholine receptor binding (ortholog); INVOLVED IN acetylcholine receptor signaling pathway (ortholog); desensitization of G protein-coupled receptor signaling pathway (ortholog); FOUND IN plasma membrane (orth olog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol | 20 | 3749352 | 3752578 | Rat | 42 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1309100 | Lztr1 | leucine zipper like post translational regulator 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN negative regulation of Ras protein signal transduction (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein ubiquitin ation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); bladder exstrophy (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); endomembrane system (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; endosulfan; methimazole | 11 | 96991956 | 97008127 | Rat | 123 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359249 | Lzts2 | leucine zipper tumor suppressor 2 | INVOLVED IN negative regulation of fibroblast proliferation; positive regulation of apoptotic process; kidney development (ortholog); ASSOCIATED WITH urinary system disease (ortholog); FOUND IN centrosome; midbody; mitotic spindle pole; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenz odioxine; 2,4-dinitrotoluene | 1 | 253824073 | 253837614 | Rat | 110 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563692 | Mab21l4 | mab-21 like 4 | INTERACTS WITH acetamide; bisphenol A; Cuprizon | 9 | 101138408 | 101148516 | Rat | 45 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309175 | Mad2l1bp | MAD2L1 binding protein | INVOLVED IN deactivation of mitotic spindle assembly checkpoint (ortholog); regulation of exit from mitosis (ortholog); ASSOCIATED WITH Zellweger syndrome (ortholog); FOUND IN cytoplasm (ortholog); nuclear membrane (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2 ,4-dinitrotoluene; acrylamide | 9 | 22329699 | 22334024 | Rat | 64 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311297 | Mak16 | MAK16 homolog | FOUND IN nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 16 | 67675757 | 67684188 | Rat | 97 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310869 | Mall | mal, T-cell differentiation protein-like | FOUND IN clathrin-coated vesicle (ortholog); cytoplasmic vesicle (ortholog); Golgi membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 3 | 135381180 | 135404136 | Rat | 93 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561447 | Manbal | mannosidase beta like | FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; finasteride | 3 | 166455067 | 166484652 | Rat | 44 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306620 | Map2k3 | mitogen activated protein kinase kinase 3 | ENCODES a protein that exhibits MAP kinase kinase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide; cellular response to sorbitol; heart development; PARTICIPATES IN p38 MAPK signaling pathway; Fc epsilon receptor mediated signaling pathway; interleukin-12 signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; Myocardial Ischemia; retinal disease; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 46107639 | 46128986 | Rat | 249 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1561227 | Map3k13 | mitogen-activated protein kinase kinase kinase 13 | ENCODES a protein that exhibits enzyme binding (ortholog); identical protein binding (ortholog); IkappaB kinase complex binding (ortholog); INVOLVED IN JNK cascade (ortholog); positive regulation of axon extension (ortholog); positive regulation of branching morphogenesis of a nerve (ortholog); PART ICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH gastroesophageal adenocarcinoma (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 92596436 | 92741717 | Rat | 147 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359474 | Map3k7cl | MAP3K7 C-terminal like | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; atrazine | 11 | 40276839 | 40321848 | Rat | 63 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564113 | Mapkapk5 | MAPK activated protein kinase 5 | ENCODES a protein that exhibits mitogen-activated protein kinase binding (ortholog); p53 binding (ortholog); protein kinase activity (ortholog); INVOLVED IN negative regulation of TOR signaling (ortholog); positive regulation of dendritic spine development (ortholog); positive regulation of telomere maintenance (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH NEUROCARDIOFACIODIGITAL SYNDROME (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH copper atom; copper(0); cypermethrin | 12 | 40654220 | 40673740 | Rat | 92 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305617 | Marchf5 | membrane associated ring-CH-type finger 5 | ENCODES a protein that exhibits GTPase binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of cytoplasmic pattern recognition receptor signaling pathway (ortholog); positive regulation of cGAS/STING signaling pathway (ortholog); positive regulation of mi tochondrial fission (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); mitochondrial outer membrane (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 1 | 244343674 | 244365160 | Rat | 112 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359410 | Matn1 | matrilin 1 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN chondrocyte differentiation (ortholog); growth plate cartilage chondrocyte morphogenesis (ortholog); regulation of bone mineralization (ortholog); FOUND IN extracellular matrix (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorod ibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 5 | 148401364 | 148411256 | Rat | 41 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305980 | Mbd1 | methyl-CpG binding domain protein 1 | ENCODES a protein that exhibits chromatin binding; DNA binding (ortholog); double-stranded methylated DNA binding (ortholog); INVOLVED IN epigenetic regulation of gene expression; negative regulation of astrocyte differentiation; negative regulation of gene expression; PARTICIPATES IN DNA modificati on pathway; ASSOCIATED WITH Experimental Seizures; transient cerebral ischemia; autistic disorder (ortholog); FOUND IN chromatin; cytoplasm (ortholog); heterochromatin (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 18 | 70145093 | 70159744 | Rat | 161 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307389 | Mbd3 | methyl-CpG binding domain protein 3 | ENCODES a protein that exhibits DNA binding (ortholog); methyl-CpG binding (ortholog); INVOLVED IN embryonic organ development; epigenetic regulation of gene expression; response to bisphenol A; PARTICIPATES IN CHD family mediated chromatin remodeling pathway; ASSOCIATED WITH Experimental Seizures; transient cerebral ischemia; autistic disorder (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); heterochromatin (ortholog); INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 7 | 9961053 | 9970845 | Rat | 138 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303018 | Mcm7 | minichromosome maintenance complex component 7 | ENCODES a protein that exhibits DNA helicase activity (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus; response to xenobiotic stimulus; cell population proliferation (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; DNA rep lication pathway; ASSOCIATED WITH hyperthyroidism; astigmatism (ortholog); hepatocellular carcinoma (ortholog); FOUND IN MCM complex (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 22155921 | 22163320 | Rat | 278 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302933 | Mcpt1l3 | mast cell protease 1-like 3 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); INTERACTS WITH indole-3-methanol; vinclozolin | 15 | 33806391 | 33809219 | Rat | 8 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1560271 | Mdfi | MyoD family inhibitor | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); identical protein binding (ortholog); protein sequestering activity (ortholog); INVOLVED IN dorsal/ventral axis specification (ortholog); embryonic skeletal system morphogenesis (ortholog); maintenance of protein lo cation in cell (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acrylamide; alpha-Zearalanol | 9 | 20654359 | 20672768 | Rat | 83 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310440 | Meaf6 | MYST/Esa1-associated factor 6 | ENCODES a protein that exhibits histone H3K14 acetyltransferase activity (ortholog); histone H4K12 acetyltransferase activity (ortholog); histone H4K5 acetyltransferase activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulat ion of cell cycle (ortholog); regulation of cell growth (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN kinetochore (ortholog); MOZ/MORF histone acetyltransferase complex (ortholog); NuA4 histone acetyltransferase complex (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; bisphenol A | 5 | 142628281 | 142653076 | Rat | 76 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1564993 | Med27 | mediator complex subunit 27 | ENCODES a protein that exhibits ubiquitin protein ligase activity; transcription coactivator activity (ortholog); INVOLVED IN protein ubiquitination; regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcript ion pathway; ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); NEURODEVELOPMENTAL DISORDER WITH SPASTICITY, CATARACTS, AND CEREBELLAR HYPOPLASIA (ortholog); FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene | 3 | 33027240 | 33201240 | Rat | 90 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310296 | Med6 | mediator complex subunit 6 | ENCODES a protein that exhibits ubiquitin protein ligase activity; DNA binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN protein ubiquitination; positive regulation of transcription by RNA polymerase II (ortholog); stem cell population maintenance (ortholog); PARTICIPATE S IN RNA polymerase II transcription pathway; FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 6 | 107001664 | 107015130 | Rat | 80 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561733 | Mef2b | myocyte enhancer factor 2B | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); histone deacetylase binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); regulat ion of DNA-templated transcription (ortholog); FOUND IN transcription regulator complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 16 | 19286951 | 19305547 | Rat | 85 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560341 | Metap2-ps1 | methionyl aminopeptidase 2, pseudogene 1 | ENCODES a pseudogene that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); initiator methionyl aminopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH 4,4'-sulfonyldiphenol; atrazine; bisphenol A | 18 | 51809682 | 51811667 | Rat | 22 | old_protein_id | gene, pseudo, INFERRED [RefSeq] |
| 1304822 | Mettl14 | methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit | ENCODES a protein that exhibits mRNA binding (ortholog); mRNA m(6)A methyltransferase activity (ortholog); S-adenosyl-L-methionine binding (ortholog); INVOLVED IN response to nutrient levels; forebrain radial glial cell differentiation (ortholog); gliogenesis (ortholog); ASSOCIATED WITH traumatic br ain injury; Arsenic Poisoning (ortholog); cardiomyopathy (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); RNA N6-methyladenosine methyltransferase complex (ortholog); INTERACTS WITH all-trans-retinoic acid; azoxystrobin; bisphenol A | 2 | 214215165 | 214231412 | Rat | 159 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304978 | Mettl15 | methyltransferase 15, mitochondrial 12S rRNA N4-cytidine | ENCODES a protein that exhibits rRNA (cytosine-N4-)-methyltransferase activity (ortholog); INVOLVED IN mitochondrial small ribosomal subunit assembly (ortholog); rRNA base methylation (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodi benzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 3 | 116041480 | 116219011 | Rat | 74 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311750 | Mettl3 | methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit | ENCODES a protein that exhibits mRNA binding (ortholog); mRNA m(6)A methyltransferase activity (ortholog); mRNA N6-methyladenosine dioxygenase activity (ortholog); INVOLVED IN cellular response to UV (ortholog); chromosomal DNA methylation maintenance following DNA replication (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH Emphysema (ortholog); liver cirrhosis (ortholog); multiple myeloma (ortholog); FOUND IN cytosol (ortholog); nuclear body (ortholog); nuclear speck (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 15 | 27476659 | 27491134 | Rat | 217 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1566062 | Mettl5 | methyltransferase 5, N6-adenosine | ENCODES a protein that exhibits rRNA (adenine-N6-)-methyltransferase activity (ortholog); S-adenosyl-L-methionine binding (ortholog); INVOLVED IN positive regulation of translation (ortholog); rRNA methylation (ortholog); rRNA processing (ortholog); ASSOCIATED WITH autosomal recessive intellectual d evelopmental disorder 72 (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (ortholog); fibrillar center (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 3 | 75033605 | 75046359 | Rat | 93 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310174 | Mfsd2a | MFSD2 lysolipid transporter A, lysophospholipid | ENCODES a protein that exhibits fatty acid transmembrane transporter activity (ortholog); long-chain fatty acid transmembrane transporter activity (ortholog); lysophosphatidylcholine flippase activity (ortholog); INVOLVED IN brain development (ortholog); cellular response to starvation (ortholog); c ognition (ortholog); ASSOCIATED WITH cryptorchidism (ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN lysosome (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 140510933 | 140525828 | Rat | 279 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310132 | Mfsd8 | major facilitator superfamily domain containing 8 | ENCODES a protein that exhibits chloride channel activity (ortholog); fluoride channel activity (ortholog); iodide transmembrane transporter activity (ortholog); INVOLVED IN apoptotic process (ortholog); astrocyte differentiation (ortholog); autophagosome maturation (ortholog); ASSOCIATED WITH cone- rod dystrophy (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN endosome membrane (ortholog); lysosomal membrane (ortholog); lysosome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 125749994 | 125784689 | Rat | 145 | old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1562836 | Mgat4b | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B | ENCODES a protein that exhibits acetylglucosaminyltransferase activity (ortholog); alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity (ortholog); glycosyltransferase activity (ortholog); INVOLVED IN glycoprotein biosynthetic process (ortholog); protein N-linked glycosylat ion (ortholog); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 10 | 35049421 | 35060307 | Rat | 103 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359351 | Mgat4f | MGAT4 family, member F | INTERACTS WITH trichloroethene | 13 | 48389451 | 48394857 | Rat | 3 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307465 | Mgme1 | mitochondrial genome maintenance exonuclease 1 | ENCODES a protein that exhibits 5'-flap endonuclease activity (ortholog); single-stranded DNA 5'-3' DNA exonuclease activity (ortholog); INVOLVED IN mitochondrial DNA replication (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Emaciation (ortholog); genetic disease (ortholog); FOUND IN mitochondrio n (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; indole-3-methanol | 3 | 152094514 | 152103314 | Rat | 76 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1312005 | Minar2 | membrane integral NOTCH2 associated receptor 2 | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN angiogenesis (ortholog); apoptotic process (ortholog); exploration behavior (ortholog); ASSOCIATED WITH Autosomal Recessive Nonsyndromic Deafness 120 (ortholog); Parkinson's disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); lysosomal membrane (ortholog); stereocilium (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 18 | 54737670 | 54752388 | Rat | 40 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308814 | Mkks | MKKS centrosomal shuttling protein | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN artery smooth muscle contraction (ortholog); brain morphogenesis (ortholog); cartilage development (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bardet-Biedl sy ndrome 1 (ortholog); Bardet-Biedl Syndrome 2/6, Digenic (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); cytoplasm (ortholog); INTERACTS WITH bisphenol A; cadmium atom; cadmium dichloride | 3 | 144654563 | 144672831 | Rat | 153 | UniProt | gene, protein-coding, REVIEWED [RefSeq] |
| 1310618 | Mkrn2 | makorin, ring finger protein, 2 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); negative regulation of non-canonical NF-kappaB signal transduction (ortholog); ubiquitin-dependent protein catabolic process (ortho log); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 4 | 150334164 | 150352271 | Rat | 78 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308590 | Mlx | MAX dimerization protein MLX | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); nucleocytoplasmic transport (ortholog); ASSOCIATED WITH oligoasthenoteratozoospermia (ortholog); Takayasu's arteritis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amiodarone | 10 | 86519517 | 86524607 | Rat | 130 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306506 | Mmd2 | monocyte to macrophage differentiation-associated 2 | ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN positive regulation of neuron differentiation (ortholog); positive regulation of protein kinase activity (ortholog); positive regulation of Ras protein signal transduction (ortholog); FOUND IN Golgi membrane (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 12 | 17075870 | 17123255 | Rat | 94 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311376 | Mmp19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); INVOLVED IN luteolysis; ovarian follicle development; ovulation from ovarian follicle; ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN extracellul ar matrix (inferred); extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 7 | 1805732 | 1814054 | Rat | 125 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308187 | Mob3a | MOB kinase activator 3A | ENCODES a protein that exhibits metal ion binding (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 7 | 9661185 | 9678584 | Rat | 62 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309274 | Mok | MOK protein kinase | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); ASSOCIATED WITH mucopolysaccharidosis type IIID (ortholog); renal cell carcinoma (ortholog); FOUND IN ciliary base (ortholog); cilium (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acetamide | 6 | 135645018 | 135675894 | Rat | 89 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563988 | Morn2 | MORN repeat containing 2 | INTERACTS WITH acetamide; acrylamide; bisphenol A | 6 | 20471036 | 20477520 | Rat | 60 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1304973 | Mospd3 | motile sperm domain containing 3 | INVOLVED IN heart development (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); FOUND IN membrane (inferred); INTERACTS WITH (+)-schisandrin B; bisphenol A; chlormequat chloride | 12 | 24728012 | 24737078 | Rat | 64 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564036 | Mrnip | MRN complex interacting protein | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN DNA damage response (ortholog); mitotic G2 DNA damage checkpoint signaling (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); FOUND IN Mre11 complex (ortholog); nucleoplasm ( ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; azoxystrobin | 10 | 35002440 | 35026555 | Rat | 68 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359587 | Mrpl13 | mitochondrial ribosomal protein L13 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Mouth Neoplasms (ortholog); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrial ribosom e (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 7 | 88841265 | 88862821 | Rat | 91 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306387 | Mrpl18 | mitochondrial ribosomal protein L18 | ENCODES a protein that exhibits 5S rRNA binding (ortholog); INVOLVED IN rRNA import into mitochondrion (ortholog); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 1 | 50384951 | 50389769 | Rat | 95 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359397 | Mrpl34 | mitochondrial ribosomal protein L34 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 16 | 18186447 | 18187182 | Rat | 73 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304915 | Mrpl42 | mitochondrial ribosomal protein L42 | FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrial small ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol | 7 | 32004863 | 32028640 | Rat | 65 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309556 | Mrpl44 | mitochondrial ribosomal protein L44 | ENCODES a protein that exhibits double-stranded RNA binding (inferred); endonuclease activity (inferred); hydrolase activity (inferred); INVOLVED IN mitochondrial translational elongation (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 1 (ortholog); combined oxidative phosp horylation deficiency 16 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,6-dinitrotoluene; azoxystrobin; bisphenol A | 9 | 88555050 | 88560101 | Rat | 80 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307531 | Mrpl47 | mitochondrial ribosomal protein L47 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 2 | 117436199 | 117447790 | Rat | 70 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309432 | Mrps14 | mitochondrial ribosomal protein S14 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN mitochondrial translation (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 38 (ortholog); FOUND IN mitochondrial small ribosomal subunit (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A | 13 | 74962597 | 74968344 | Rat | 85 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309217 | Mrps33 | mitochondrial ribosomal protein S33 | ASSOCIATED WITH bipolar disorder (ortholog); FOUND IN mitochondrion (inferred); ribonucleoprotein complex (inferred); ribosome (inferred); INTERACTS WITH 3-chloropropane-1,2-diol; acetamide; aconitine | 4 | 69563501 | 69572317 | Rat | 87 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306558 | Mrps9 | mitochondrial ribosomal protein S9 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 9 | 52605678 | 52664499 | Rat | 60 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311761 | Ms4a6b | membrane-spanning 4-domains, subfamily A, member 6B | FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol | 1 | 217705785 | 217727719 | Rat | 22 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359381 | Ms4a6bl1 | membrane-spanning 4-domains, subfamily A, member 6B-like 1 | FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil | 1 | 217668326 | 217680151 | Rat | 17 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561674 | Msantd5 | Myb/SANT DNA binding domain containing 5 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; paracetamol; thioacetamide | 10 | 36017911 | 36026389 | Rat | 4 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549763 | Msl3 | MSL complex subunit 3 | ENCODES a protein that exhibits DNA binding (ortholog); histone H4K16ac reader activity (ortholog); histone reader activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Basilicata-Akhtar s yndrome (ortholog); Craniofacial Abnormalities (ortholog); Developmental Disabilities (ortholog); FOUND IN MSL complex (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; C60 fullerene; clofibric acid | X | 29210388 | 29228060 | Rat | 92 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306743 | Mta2 | metastasis associated 1 family, member 2 | ENCODES a protein that exhibits histone deacetylase binding; histone deacetylase activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN regulation of fibroblast migration; chromatin remodeling (ortholog); genomic imprinting (ortholog); PARTIC IPATES IN CHD family mediated chromatin remodeling pathway; ASSOCIATED WITH endometriosis (ortholog); systemic lupus erythematosus (ortholog); FOUND IN chromosome, telomeric region (ortholog); histone deacetylase complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 1 | 215267286 | 215276008 | Rat | 122 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359705 | Mtfp1 | mitochondrial fission process 1 | INVOLVED IN response to muscle activity; apoptotic process (ortholog); mitochondrial fission (ortholog); PARTICIPATES IN mitochondria fission pathway; ASSOCIATED WITH neuroblastoma (ortholog); Parkinson's disease 6 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog ); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 14 | 83192013 | 83195853 | Rat | 90 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306876 | Mthfs | methenyltetrahydrofolate synthetase | ENCODES a protein that exhibits 5-formyltetrahydrofolate cyclo-ligase activity (ortholog); ATP binding (ortholog); folic acid binding (ortholog); INVOLVED IN folic acid catabolic process (ortholog); glutamate metabolic process (ortholog); tetrahydrofolate interconversion (ortholog); PARTICIPATES IN folate metabolic pathway; hereditary folate malabsorption pathway; methotrexate pharmacodynamics pathway; ASSOCIATED WITH cleft lip (ortholog); cleft palate (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial matrix (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,4-dinitrotoluene | 8 | 98609410 | 98681901 | Rat | 84 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303046 | Mtif2 | mitochondrial translational initiation factor 2 | ENCODES a protein that exhibits translation initiation factor activity (ortholog); INVOLVED IN formation of translation preinitiation complex (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloroprop ane-1,2-diol | 14 | 107465719 | 107486663 | Rat | 90 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306473 | Mtx2 | metaxin 2 | INVOLVED IN mitochondrial transport (ortholog); PARTICIPATES IN beta-barrel pathway of mitochondrial protein import; ASSOCIATED WITH Mandibuloacral Dysplasia Progeroid Syndrome (ortholog); megacolon (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol ; amitrole | 3 | 80137556 | 80199547 | Rat | 71 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304865 | Muc20 | mucin 20, cell surface associated | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN hepatocyte growth factor receptor signaling pathway (ortholog); positive regulation of MAPK cascade (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); IgA glomerulonephritis (ortholog); lupus nephritis (ortho log); FOUND IN basal plasma membrane (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; amphetamine; bisphenol A | 11 | 81492844 | 81506571 | Rat | 54 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1566134 | Mup4l1 | major urinary protein 4 like 1 | ENCODES a protein that exhibits insulin receptor activity (ortholog); pheromone binding (ortholog); INVOLVED IN aerobic respiration (ortholog); cellular response to lipid (ortholog); energy reserve metabolic process (ortholog); FOUND IN extracellular space; cytosol (ortholog); nucleus (ortholog); IN TERACTS WITH 1-naphthyl isothiocyanate; 3-chloropropane-1,2-diol; acetamide | 5 | 80223093 | 80226566 | Rat | 35 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1307994 | Myh7b | myosin heavy chain 7B | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); ATP binding (inferred); INVOLVED IN regulation of calcium-mediated signaling; regulation of CAMKK-AMPK signaling cascade; regulation of cardiac muscle cell contraction; PARTICIPATES IN myocarditis pathway; A SSOCIATED WITH abnormal myocardial fiber calcium currents; abnormal sarcomere morphology; cardiac fibrosis; ASSOCIATED WITH hypertrophic cardiomyopathy; Contracture (ortholog); Dilated Cardiomyopathy with Left Ventricular Noncompaction (ortholog); FOUND IN cardiac myofibril (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil | 3 | 164537211 | 164582441 | Rat | 94 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311235 | Myl9 | myosin light chain 9 | ENCODES a protein that exhibits myosin heavy chain binding (ortholog); structural constituent of cytoskeleton (ortholog); INVOLVED IN platelet aggregation (ortholog); stress fiber assembly (ortholog); ASSOCIATED WITH brain edema (ortholog); Experimental Liver Cirrhosis (ortholog); familial hypertrop hic cardiomyopathy (ortholog); FOUND IN myosin II complex (ortholog); stress fiber (ortholog); Z disc (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 165742020 | 165748409 | Rat | 249 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307889 | Mynn | myoneurin | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH chronic recurrent multifocal osteomyelitis (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 2 | 114708150 | 114726450 | Rat | 72 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307713 | Naa20 | N(alpha)-acetyltransferase 20, NatB catalytic subunit | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); protein N-terminal-methionine acetyltransferase activity (inferred); INVOLVED IN N-terminal peptidyl-aspartic acid acetylation (ortholog); N-ter minal peptidyl-glutamic acid acetylation (ortholog); N-terminal peptidyl-glutamine acetylation (ortholog); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 73 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione | 3 | 153775351 | 153790129 | Rat | 85 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308642 | Naca | nascent polypeptide associated complex subunit alpha | ENCODES a protein that exhibits TBP-class protein binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN myoblast migration (ortholog); negative regulation of protein localization to endoplasmic reticulum (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); FOUND IN cy toplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 7 | 1053474 | 1066606 | Rat | 101 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311943 | Nans | N-acetylneuraminate synthase | ENCODES a protein that exhibits N-acylneuraminate-9-phosphate synthase activity (ortholog); INVOLVED IN CMP-N-acetylneuraminate biosynthetic process (ortholog); N-acetylneuraminate biosynthetic process (ortholog); N-acetylneuraminate metabolic process (ortholog); PARTICIPATES IN amino sugar metaboli c pathway; french type sialuria pathway; sialic acid storage disease pathway; ASSOCIATED WITH bone development disease (ortholog); Desbuquois dysplasia (ortholog); Developmental Disabilities (ortholog); FOUND IN cytosol; nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; alpha-Zearalanol; bisphenol A | 5 | 65575970 | 65593164 | Rat | 141 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307096 | Nat9 | N-acetyltransferase 9 | ENCODES a protein that exhibits acyltransferase activity (inferred); acyltransferase activity, transferring groups other than amino-acyl groups (inferred); N-acetyltransferase activity (inferred); FOUND IN protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-d initrotoluene; bisphenol A | 10 | 100921306 | 100926646 | Rat | 42 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563014 | Ncoa4 | nuclear receptor coactivator 4 | ENCODES a protein that exhibits transcription coactivator activity (inferred); INVOLVED IN response to hormone; intracellular iron ion homeostasis (ortholog); protein targeting to lysosome (ortholog); PARTICIPATES IN iron homeostasis pathway; thyroid cancer pathway; ASSOCIATED WITH invasive ductal c arcinoma (ortholog); ovarian carcinoma (ortholog); polycystic ovary syndrome (ortholog); FOUND IN autolysosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 16 | 7395502 | 7415846 | Rat | 188 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310154 | Ndc80 | NDC80 kinetochore complex component | ENCODES a protein that exhibits cyclin binding (ortholog); identical protein binding (ortholog); kinetochore adaptor activity (ortholog); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); attachment of spindle microtubules to kinetochore (ortholog); centrosome duplica tion (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); hepatocellular carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); kinetochore (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 9 | 118853806 | 118887582 | Rat | 253 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560955 | Ndufa1 | NADH:ubiquinone oxidoreductase subunit A1 | INVOLVED IN respiratory electron transport chain (inferred); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; ASSOCIATED WITH genetic disease (ortholog); mitochondrial complex I deficiency (ortholog); nuclear type mitochondrial complex I de ficiency 12 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 17beta-estradiol | X | 121289904 | 121293555 | Rat | 126 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1304597 | Ndufa7 | NADH:ubiquinone oxidoreductase subunit A7 | INVOLVED IN ATP synthesis coupled electron transport (inferred); respiratory electron transport chain (inferred); vesicle-mediated transport (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A | 7 | 15311446 | 15324226 | Rat | 102 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306283 | Ndufa8 | NADH:ubiquinone oxidoreductase subunit A8 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (inferred); respiratory electron transport chain (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphoryl ation pathway; ASSOCIATED WITH Nuclear Type Mitochondrial Complex I Deficiency 37 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial intermembrane space (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 39783479 | 39799507 | Rat | 113 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308130 | Ndufb2 | NADH:ubiquinone oxidoreductase subunit B2 | INVOLVED IN respiratory electron transport chain (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WIT H 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; bisphenol A | 4 | 69334307 | 69341394 | Rat | 119 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309129 | Ndufb8 | NADH:ubiquinone oxidoreductase subunit B8 | INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (inferred); respiratory electron transport chain (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH acute kidney failure; Kidney Reperfusion Injury; Sepsis; FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 253357878 | 253362936 | Rat | 164 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1307511 | Ndufc2 | NADH:ubiquinone oxidoreductase subunit C2 | INVOLVED IN mitochondrial respiratory chain complex I assembly; negative regulation of cellular process; negative regulation of non-canonical NF-kappaB signal transduction; PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH f ailure of embryo implantation; increased urine protein level; ASSOCIATED WITH stroke; intellectual disability (ortholog); Nuclear Type Mitochondrial Complex I Deficiency 36 (ortholog); FOUND IN cytoplasm (ortholog); mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 161122370 | 161129413 | Rat | 122 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310013 | Ndufs7 | NADH:ubiquinone oxidoreductase core subunit S7 | ENCODES a protein that exhibits protease binding; NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (ortholog); PARTICIPATES IN d oxorubicin pharmacokinetics pathway; Alzheimer's disease pathway; Huntington's disease pathway; ASSOCIATED WITH bipolar disorder (ortholog); COVID-19 (ortholog); developmental disorder of mental health (ortholog); FOUND IN neuronal cell body; synaptic membrane; mitochondrial inner membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 10103226 | 10110862 | Rat | 136 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309436 | Ndufs8 | NADH:ubiquinone oxidoreductase core subunit S8 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (ortholog); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 1 | 210569823 | 210573707 | Rat | 150 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359247 | Ndufv1 | NADH:ubiquinone oxidoreductase core subunit V1 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN mitochondrial ATP synthesis coupled electron transport (ortholog); mitochondrial electron transport, NADH to ubiquinone (ortholog); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathw ay; oxidative phosphorylation pathway; ASSOCIATED WITH autosomal recessive spinocerebellar ataxia 8 (ortholog); Disease Progression (ortholog); genetic disease (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 1 | 210729856 | 210735103 | Rat | 158 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306276 | Nedd9 | neural precursor cell expressed, developmentally down-regulated 9 | ENCODES a protein that exhibits protein tyrosine kinase binding (ortholog); INVOLVED IN activation of GTPase activity (ortholog); cilium disassembly (ortholog); learning or memory (ortholog); ASSOCIATED WITH multiple sclerosis (ortholog); FOUND IN basolateral plasma membrane (ortholog); ciliary basa l body (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 17 | 23495531 | 23673780 | Rat | 264 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306077 | Neil1 | nei-like DNA glycosylase 1 | ENCODES a protein that exhibits DNA N-glycosylase activity (ortholog); hydrolase activity, acting on glycosyl bonds (ortholog); lyase activity (ortholog); INVOLVED IN base-excision repair (ortholog); DNA repair (ortholog); PARTICIPATES IN base excision repair pathway; ASSOCIATED WITH abdominal obesi ty-metabolic syndrome (ortholog); Dyslipidemias (ortholog); familial hyperlipidemia (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; amphetamine; aniline | 8 | 66446106 | 66452844 | Rat | 118 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305556 | Nelfa | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding; molecular adaptor activity (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN positive regulation of protein modification process; positive regulation of transcription by RNA polymerase II; negative regulation of transcription elo ngation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 14 | 81033470 | 81057546 | Rat | 99 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564984 | Neurl1b | neuralized E3 ubiquitin protein ligase 1B | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN ubiquitin-dependent endocytosis (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytosol (ortholog); early endosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenz odioxine; acetamide | 10 | 17258317 | 17289362 | Rat | 110 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1306409 | Neurl2 | neuralized E3 ubiquitin protein ligase 2 | INVOLVED IN myofibril assembly (ortholog); sarcomere organization (ortholog); PARTICIPATES IN Notch signaling pathway; FOUND IN muscle tendon junction (ortholog); VCB complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 173985996 | 173988717 | Rat | 72 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562793 | Neurod6 | neuronal differentiation 6 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN dentate gyrus development (ortholog); positive regulation of transcription by RNA polymer ase II (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; benzo[a]pyrene | 4 | 86176909 | 86180155 | Rat | 45 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310277 | Nfx1 | nuclear transcription factor, X-box binding 1 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of MHC class II biosynthetic process (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); protein autoubiquitination (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; acetamide | 5 | 60900140 | 60958889 | Rat | 112 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1566421 | Nipsnap2 | nipsnap homolog 2 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN mitochondrion organization (ortholog); mitophagy (ortholog); positive regulation of high voltage-gated calcium channel activity (ortholog); FOUND IN cytoplasm (ortholog); mitochondrial matrix (ortholog); m itochondrial outer membrane (ortholog); INTERACTS WITH atrazine; bisphenol A; Brodifacoum | 12 | 32542171 | 32580345 | Rat | 91 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308560 | Nkiras1 | NFKB inhibitor interacting Ras-like 1 | ENCODES a protein that exhibits GTPase activating protein binding (ortholog); INVOLVED IN lung alveolus development (ortholog); Ral protein signal transduction (ortholog); regulation of tumor necrosis factor-mediated signaling pathway (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-t etrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil | 15 | 9924316 | 9934538 | Rat | 69 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306149 | Nkx2-6 | NK2 homeobox 6 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN atrial cardiac muscle cell developm ent (ortholog); cell differentiation (ortholog); digestive tract development (ortholog); ASSOCIATED WITH cerebral palsy (ortholog); Conotruncal Cardiac Defects (ortholog); familial atrial fibrillation (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole | 15 | 50852965 | 50857060 | Rat | 74 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305369 | Nkx3-1 | NK3 homeobox 1 | ENCODES a protein that exhibits cysteine-type endopeptidase activator activity involved in apoptotic process (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN androgen receptor signaling pathway (ortholog); branching involved in prostate gland morp hogenesis (ortholog); branching morphogenesis of an epithelial tube (ortholog); PARTICIPATES IN forkhead class A signaling pathway; prostate cancer pathway; ASSOCIATED WITH abnormal copulatory plug deposition; decreased litter size; decreased prostate gland weight; ASSOCIATED WITH hepatocellular carcinoma (ortholog); prostate cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); site of DNA damage (ortholog); INTERACTS WITH acrylamide; bisphenol A; C60 fullerene | 15 | 50883661 | 50886253 | Rat | 200 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308301 | Nle1 | notchless homolog 1 | INVOLVED IN hematopoietic stem cell homeostasis (ortholog); inner cell mass cell differentiation (ortholog); kidney development (ortholog); FOUND IN nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 68331609 | 68342562 | Rat | 99 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308468 | Nmd3 | NMD3 ribosome export adaptor | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); ribosomal large subunit binding (ortholog); INVOLVED IN positive regulation of protein localization to nucleolus (ortholog); positive regulation of RNA biosynthetic process (ortholog); ribosomal large subunit export f rom nucleus (ortholog); PARTICIPATES IN ribosome biogenesis pathway; RNA transport pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 2 | 156285773 | 156348394 | Rat | 99 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1309140 | Nmnat3 | nicotinamide nucleotide adenylyltransferase 3 | ENCODES a protein that exhibits nicotinamide-nucleotide adenylyltransferase activity (ortholog); nicotinate-nucleotide adenylyltransferase activity (ortholog); INVOLVED IN response to tumor necrosis factor; NAD+ biosynthetic process (ortholog); NAD+ biosynthetic process via the salvage pathway (orth olog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH glaucoma; polycystic ovary syndrome (ortholog); FOUND IN axon; neuronal cell body; mitochondrial matrix (ortholog); INTERACTS WITH 2,6-dinitrotoluene; acetamide; aflatoxin B1 | 8 | 107771124 | 107888528 | Rat | 109 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303085 | Nop53 | NOP53 ribosome biogenesis factor | ENCODES a protein that exhibits 5S rRNA binding (ortholog); identical protein binding (ortholog); p53 binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); DNA damage response (ortholog); DNA repair (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); FOUND IN cytosol (ortholog); fibrillar center (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; aristolochic acid A | 1 | 85757271 | 85765089 | Rat | 143 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308892 | Nop56 | NOP56 ribonucleoprotein | ENCODES a protein that exhibits histone methyltransferase binding (ortholog); RNA binding (ortholog); snoRNA binding (ortholog); INVOLVED IN ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Animal Disease Models (ortholog); cerebellar ataxia (ortholog); Disease Progression (ortholog); FOUND IN box C/D methylation guide snoRNP complex (ortholog); fibrillar center (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 137926187 | 137934971 | Rat | 183 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303282 | Notch4 | notch receptor 4 | ENCODES a protein that exhibits Notch binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN endothelial cell differentiation; endothelial cell morphogenesis; luteolysis; PARTICIPATES IN Notch signaling pathway; altered Notch signaling pathway; Notch signaling pathway; ASSOCI ATED WITH AIDS-Associated Nephropathy; Hypertrophic Cicatrix; alopecia areata (ortholog); FOUND IN cell surface (ortholog); cytoplasmic vesicle (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 3-methylfuran | 20 | 4164969 | 4189072 | Rat | 187 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303156 | Npdc1 | neural proliferation, differentiation and control, 1 | ENCODES a protein that exhibits ATP binding (inferred); hydrolase activity (inferred); nucleotide binding (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyan ate; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 28618601 | 28624591 | Rat | 91 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359166 | Npm1-ps1 | nucleophosmin 1, pseudogene 1 | | 16 | 30902967 | 30904234 | Rat | | old_protein_id | gene, pseudo, INFERRED [RefSeq] |
| 1561190 | Nr2c2ap | nuclear receptor 2C2-associated protein | FOUND IN nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol | 16 | 19322395 | 19324912 | Rat | 69 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304603 | Nrf1 | nuclear respiratory factor 1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN animal organ regeneration; response to electrical stimulus; response to estradiol; PARTIC IPATES IN Huntington's disease pathway; ASSOCIATED WITH Brain Hypoxia-Ischemia; Hypoxia; obesity; FOUND IN nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; (R)-noradrenaline; 17beta-estradiol | 4 | 59632366 | 59738166 | Rat | 273 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309535 | Nsun6 | NOP2/Sun RNA methyltransferase 6 | ENCODES a protein that exhibits tRNA (cytidine-5-)-methyltransferase activity (ortholog); tRNA binding (ortholog); INVOLVED IN tRNA C5-cytosine methylation (ortholog); tRNA methylation (ortholog); tRNA modification (ortholog); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 8 2 (ortholog); Breast Neoplasms (ortholog); cardiomyopathy (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 17 | 82820938 | 82864140 | Rat | 83 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310137 | Nsun7 | NOP2/Sun RNA methyltransferase family member 7 | ENCODES a protein that exhibits methyltransferase activity (inferred); RNA binding (inferred); transferase activity (inferred); INVOLVED IN flagellated sperm motility (ortholog); sperm mitochondrion organization (ortholog); ASSOCIATED WITH male infertility (ortholog); INTERACTS WITH 6-propyl-2-thiou racil; acrylamide; amitrole | 14 | 42233062 | 42289013 | Rat | 53 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1312013 | Nt5c3a | 5'-nucleotidase, cytosolic IIIA | ENCODES a protein that exhibits 5'-nucleotidase activity; INVOLVED IN adenosine metabolic process; CMP catabolic process (ortholog); dCMP catabolic process (ortholog); PARTICIPATES IN monoterpenoid biosynthetic pathway; niacin metabolic pathway; purine metabolic pathway; ASSOCIATED WITH Chloracne (o rtholog); congenital nonspherocytic hemolytic anemia (ortholog); congenital nonspherocytic hemolytic anemia 8 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 2,4-dinitrotoluene; acetamide; acrylamide | 4 | 87491828 | 87534838 | Rat | 101 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305214 | Nt5dc1 | 5'-nucleotidase domain containing 1 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); ASSOCIATED WITH melanoma (ortholog); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 20 | 39660707 | 39763647 | Rat | 75 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1359489 | Nub1 | negative regulator of ubiquitin-like proteins 1 | INVOLVED IN positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); proteasomal protein catabolic process (ortholog); protein ubiquitination (ortholog); PARTICIPATES IN neddylation pathway; FOUND IN Lewy body (ortholog); nucleolus (ortholog); nucleoplasm (ortholo g); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 4 | 11335376 | 11366263 | Rat | 80 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310624 | Nudcd1 | NudC domain containing 1 | ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; Cuprizon | 7 | 77436035 | 77480651 | Rat | 82 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1561451 | Nudt16l1 | nudix hydrolase 16 like 1 | ENCODES a protein that exhibits 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity (ortholog); protein homodimerization activity (ortholog); snoRNA binding (ortholog); INVOLVED IN negative regulation of double-strand break repair via nonhomologous end joining (ortholog); PARTICIPATES IN syndecan signaling pathway; FOUND IN nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol | 10 | 11142626 | 11144542 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308777 | Numa1 | nuclear mitotic apparatus protein 1 | ENCODES a protein that exhibits microtubule binding; disordered domain specific binding (ortholog); dynein complex binding (ortholog); INVOLVED IN meiotic cell cycle; anastral spindle assembly (ortholog); astral microtubule organization (ortholog); ASSOCIATED WITH allergic contact dermatitis (orthol og); myoepithelioma (ortholog); FOUND IN dendrite; neuronal cell body; nuclear matrix; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3'-diindolylmethane; 4,4'-sulfonyldiphenol | 1 | 165709893 | 165784848 | Rat | 236 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309327 | Nxt1 | nuclear transport factor 2-like export factor 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); protein export from nucleus (ortholog); RNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; influenza A pathway; mRNA decay pathway; FOUND IN cytosol (ortholog) ; nuclear pore (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 156562121 | 156565043 | Rat | 97 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561300 | Nyx | nyctalopin | INVOLVED IN visual perception (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); congenital stationary night blindness 1A (ortholog); congenital stationary night blindness 1C (ortholog); FOUND IN dendrite (ortholog); postsynapse (ortholog); INTERACTS WITH 6-propyl-2-thiour acil; bisphenol A; copper atom | X | 11953680 | 11974716 | Rat | 47 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359611 | Oas1e | 2'-5' oligoadenylate synthetase 1E | ENCODES a protein that exhibits nucleotidyltransferase activity (inferred); RNA binding (inferred); INVOLVED IN defense response to virus (inferred); immune system process (inferred); innate immune response (inferred); INTERACTS WITH bisphenol A; Cuprizon | 12 | 41410954 | 41419924 | Rat | 7 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359647 | Oas1f | 2 ' -5 ' oligoadenylate synthetase 1F | ENCODES a protein that exhibits nucleotidyltransferase activity (inferred); RNA binding (inferred); INVOLVED IN defense response to virus (inferred); immune system process (inferred); innate immune response (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; aflatoxin B1 | 12 | 41357647 | 41367123 | Rat | 12 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1359379 | Oas1i | 2 ' -5 ' oligoadenylate synthetase 1I | ENCODES a protein that exhibits 2'-5'-oligoadenylate synthetase activity (inferred); ATP binding (inferred); nucleotidyltransferase activity (inferred); INVOLVED IN defense response to virus (inferred); immune system process (inferred); innate immune response (inferred); FOUND IN cytoplasm (inferred ); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 12 | 41285201 | 41297242 | Rat | 29 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359279 | Oas1k | 2 ' -5 ' oligoadenylate synthetase 1K | ENCODES a protein that exhibits 2'-5'-oligoadenylate synthetase activity (inferred); nucleotidyltransferase activity (inferred); RNA binding (inferred); INVOLVED IN defense response to virus (inferred); immune system process (inferred); innate immune response (inferred); FOUND IN cytoplasm (inferred ); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-estradiol 3-benzoate | 12 | 41423100 | 41432330 | Rat | 19 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359125 | Omg | oligodendrocyte-myelin glycoprotein | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN neuron projection regeneration (ortholog); regulation of collateral sprouting of intact axon in response to injury (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN plasma membrane (infer red); side of membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol | 10 | 64959316 | 64962050 | Rat | 42 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306186 | Oog3l1 | oogenesin 3 like 1 | INVOLVED IN negative regulation of apoptotic process (inferred); negative regulation of cell differentiation (inferred); negative regulation of DNA-templated transcription (inferred) | 5 | 161358296 | 161364877 | Rat | 4 | UniProt , old_protein_id | gene, protein-coding, PREDICTED [RefSeq] |
| 1332620 | Or10c1 | olfactory receptor family 10 subfamily C member 1 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH bisphenol A; C60 fullerene; cadmium dichloride | 20 | 1375847 | 1376785 | Rat | 35 | UniProt | gene, protein-coding, REVIEWED [RefSeq] |
| 1333016 | Or10g1 | olfactory receptor family 10 subfamily G member 1 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 15 | 27619118 | 27620074 | Rat | 14 | UniProt | gene, protein-coding, REVIEWED [RefSeq] |
| 1333427 | Or10g1b | olfactory receptor family 10 subfamily G member 1B | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH ammonium chloride; bisphenol A; C60 fullerene | 15 | 27601332 | 27602288 | Rat | 24 | old_protein_id | gene, protein-coding, REVIEWED [RefSeq] |
| 1564509 | Or12d14 | olfactory receptor family 12 subfamily D member 14 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 20 | 1138000 | 1139672 | Rat | 14 | UniProt | gene, protein-coding, MODEL [RefSeq] |
| 1334001 | Or12d2 | olfactory receptor family 12 subfamily D member 2 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 20 | 1264259 | 1265185 | Rat | 20 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1332862 | Or1f20 | olfactory receptor family 1 subfamily F member 20 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 10 | 12585633 | 12643095 | Rat | 22 | UniProt | gene, protein-coding, REVIEWED [RefSeq] |
| 1332876 | Or2h2 | olfactory receptor family 2 subfamily H member 2 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 20 | 1459308 | 1460240 | Rat | 16 | old_protein_id | gene, protein-coding, REVIEWED [RefSeq] |
| 1332725 | Or2h2c | olfactory receptor family 2 subfamily H member 2C | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; bisphenol A | 20 | 1404211 | 1405149 | Rat | 36 | old_protein_id | gene, protein-coding, REVIEWED [RefSeq] |
| 1332704 | Or5ak25 | olfactory receptor family 5 subfamily AK member 25 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH ammonium chloride; bisphenol A; fenvalerate | 3 | 90904201 | 90905148 | Rat | 17 | UniProt | gene, protein-coding, REVIEWED [RefSeq] |
| 1333183 | Or8s10 | olfactory receptor family 8 subfamily S member 10 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); olfactory receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of smell (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of smell (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH bisphenol A; cadmium dichloride | 7 | 131434491 | 131460236 | Rat | 20 | UniProt | gene, protein-coding, REVIEWED [RefSeq] |
| 1310213 | Orai2 | ORAI calcium release-activated calcium modulator 2 | ENCODES a protein that exhibits store-operated calcium channel activity (ortholog); INVOLVED IN store-operated calcium entry (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; FOUND IN growth cone; cytosol (ortholog); membrane (ortholog); INTERACTS WIT H 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 12 | 26136922 | 26157041 | Rat | 92 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1561088 | Orc5 | origin recognition complex, subunit 5 | ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); INVOLVED IN DNA replication initiation (ortholog); regulation of DNA replication (ortholog); FOUND IN chromatin (ortholog); nuclear origin of replication recognition complex (ortholog); nucleoplasm (ortholog); INT ERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate | 4 | 13440264 | 13504888 | Rat | 66 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311437 | Orc6 | origin recognition complex, subunit 6 | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN DNA replication initiation (ortholog); DNA-templated DNA replication (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); genetic disease (ortholog); Meier-Gorlin syndrome (ortholog); FOUND IN fibrillar center (ortholog); nu cleoplasm (ortholog); origin recognition complex (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide | 19 | 37931085 | 37938856 | Rat | 150 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307294 | Osbpl11 | oxysterol binding protein-like 11 | ENCODES a protein that exhibits phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity (ortholog); INVOLVED IN fat cell differentiation (ortholog); lysosomal membrane organization (ortholog); phospholipid homeostasis (ortholog); FOUND IN endoplasmic reticulum-trans-Golgi network membr ane contact site (ortholog); intermembrane lipid transporter complex (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acetamide | 11 | 81038759 | 81121887 | Rat | 83 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311201 | Pabpc6 | poly(A) binding protein, cytoplasmic 6 | ENCODES a protein that exhibits poly(A) binding (ortholog); INVOLVED IN nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (inferred); RNA splicing (inferred); FOUND IN cytoplasmic stress granule (inferred); lamellipodium (inferred); spliceosomal complex (inferred); INTERACTS WITH 1 ,2-dimethylhydrazine; bisphenol A; indole-3-methanol | 1 | 53592902 | 53595978 | Rat | 63 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1565353 | Pak1ip1 | PAK1 interacting protein 1 | INVOLVED IN cell population proliferation (ortholog); regulation of signal transduction by p53 class mediator (ortholog); ribosomal large subunit biogenesis (ortholog); FOUND IN nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 17 | 23947978 | 23959055 | Rat | 110 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307705 | Pak4 | p21 (RAC1) activated kinase 4 | ENCODES a protein that exhibits protein kinase activity (ortholog); protein serine kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN dendritic spine development (ortholog); negative regulation of endothelial cell apoptotic process (ortholog); negative regul ation of triglyceride catabolic process (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; ASSOCIATED WITH clear cell renal cell carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cell junction (ortholog); cytoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; atrazine | 1 | 92977437 | 93016721 | Rat | 130 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307012 | Papss2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | ENCODES a protein that exhibits adenylylsulfate kinase activity (ortholog); sulfate adenylyltransferase (ATP) activity (ortholog); INVOLVED IN 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process (ortholog); blood coagulation (ortholog); bone development (ortholog); PARTICIPATES IN sulfite oxi dase deficiency pathway; purine metabolic pathway; selenoamino acid metabolic pathway; ASSOCIATED WITH brachyolmia (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 239867597 | 239952614 | Rat | 229 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310426 | Paqr3 | progestin and adipoQ receptor family member 3 | ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN negative regulation of MAP kinase activity (ortholog); negative regulation of neuron projection development (ortholog); negative regulation of peptid yl-serine phosphorylation (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 14 | 12766539 | 12796461 | Rat | 95 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311259 | Paqr5 | progestin and adipoQ receptor family member 5 | ENCODES a protein that exhibits metal ion binding (inferred); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol | 8 | 71327397 | 71409201 | Rat | 82 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306146 | Pask | PAS domain containing serine/threonine kinase | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN energy homeostasis (ortholog); negative regulation of glycogen biosynthetic process (ortholog); protein autophosphorylation (ortholog); ASSOCIATED WITH autistic d isorder (ortholog); chromosome 2q37 deletion syndrome (ortholog); chronic kidney disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil | 9 | 101291673 | 101333288 | Rat | 124 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308213 | Pbx1 | PBX homeobox 1 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN adrenal gland development (ortholog); animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); ASSOCIATED WITH brain infarction; glaucoma; autism spectrum disorder (ortholog); FOUND IN cytoplasm (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 13 | 82811664 | 83121447 | Rat | 248 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1307430 | Pcbp3 | poly(rC) binding protein 3 | ENCODES a protein that exhibits C-rich single-stranded DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN iron homeostasis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 20 | 11635579 | 11877721 | Rat | 88 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305870 | Pcdh18 | protocadherin 18 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN brain development (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 2 | 135982929 | 135996917 | Rat | 111 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1303209 | Pcdh7 | protocadherin 7 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN regulation of postsynapse assembly; FOUND IN glutamatergic synapse; postsynaptic density; cell junction (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 14 | 56684817 | 57114976 | Rat | 162 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308836 | Pced1a | PC-esterase domain containing 1A | INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A | 3 | 138049747 | 138076107 | Rat | 57 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311479 | Pcgf3 | polycomb group ring finger 3 | ENCODES a protein that exhibits histone H2AK119 ubiquitin ligase activity (ortholog); INVOLVED IN random inactivation of X chromosome (ortholog); PARTICIPATES IN histone modification pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); PcG protein complex (ortholog); INTERACTS WITH 17alpha- ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 14 | 1381976 | 1436709 | Rat | 71 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560558 | Pdzd9 | PDZ domain containing 9 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 1 | 184619631 | 184646553 | Rat | 20 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560925 | Pdzph1 | PDZ and pleckstrin homology domains 1 | INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 9 | 106038530 | 106176711 | Rat | 13 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311199 | Peli1 | pellino E3 ubiquitin protein ligase 1 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); ubiquitin-ubiquitin ligase activity (ortholog); INVOLVED IN negative regulation of necroptotic process (ortholog); negative regulation of T cell activation (ortholog); neg ative regulation of T cell proliferation (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; ASSOCIATED WITH Arsenic Poisoning (ortholog); colorectal cancer (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 14 | 99455970 | 99510474 | Rat | 192 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305989 | Peli3 | pellino E3 ubiquitin protein ligase family member 3 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); negative regulation of extrinsic apoptotic signaling pathway (ortholog); negative regulation of protein ubiquitination (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; amphetamine | 1 | 211659416 | 211672280 | Rat | 76 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310294 | Perp | p53 apoptosis effector related to PMP22 | INVOLVED IN amelogenesis (ortholog); desmosome organization (ortholog); heterotypic cell-cell adhesion (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Erythrokeratodermia Variabilis et Progressiva 7 (ortholog); genetic disease (ortholog); Olmsted Syndrome 2 (ortholog); FOUND IN cy toplasm (ortholog); desmosome (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 15361784 | 15374230 | Rat | 170 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310353 | Pex11b | peroxisomal biogenesis factor 11 beta | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN peroxisome fission (ortholog); peroxisome organization (ortholog); regulation of peroxisome size (ortholog); ASSOCIATED WITH cataract (ortholog); genetic disease (ortholog) ; infantile Refsum disease (ortholog); FOUND IN peroxisomal membrane; mitochondrion (ortholog); peroxisome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acrylamide | 2 | 186858222 | 186869814 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311436 | Pfdn5 | prefoldin subunit 5 | ENCODES a protein that exhibits amyloid-beta binding (ortholog); unfolded protein binding (ortholog); INVOLVED IN negative regulation of amyloid fibril formation (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of DNA-templated transcription (ortholo g); FOUND IN cytosol (ortholog); prefoldin complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 7 | 135330364 | 135335102 | Rat | 98 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303006 | Pfdn6 | prefoldin subunit 6 | ENCODES a protein that exhibits amyloid-beta binding (ortholog); protein-folding chaperone binding (ortholog); unfolded protein binding (ortholog); INVOLVED IN chaperone-mediated protein complex assembly (ortholog); negative regulation of amyloid fibril formation (ortholog); protein folding (ortholo g); FOUND IN prefoldin complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol | 20 | 4947844 | 4949318 | Rat | 85 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306061 | Pgm2 | phosphoglucomutase 2 | ENCODES a protein that exhibits phosphoglucomutase activity (ortholog); phosphopentomutase activity (ortholog); INVOLVED IN glucose metabolic process (ortholog); glycogen biosynthetic process (ortholog); glycogen catabolic process (ortholog); PARTICIPATES IN glycogen biosynthetic pathway; glycogen d egradation pathway; ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 14 | 44519906 | 44553420 | Rat | 135 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303133 | Pgpep1 | pyroglutamyl-peptidase I | ENCODES a protein that exhibits peptidase activity; INVOLVED IN protein catabolic process; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 16 | 18804408 | 18817466 | Rat | 110 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303205 | Phf1 | PHD finger protein 1 | ENCODES a protein that exhibits chromatin binding; histone H3K36me3 reader activity (ortholog); histone H3K4me3 reader activity (ortholog); INVOLVED IN DNA repair-dependent chromatin remodeling (ortholog); PARTICIPATES IN histone modification pathway; FOUND IN centrosome (ortholog); ESC/E(Z) complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil; amitrole | 20 | 5019650 | 5024732 | Rat | 109 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1308737 | Pias4 | protein inhibitor of activated STAT, 4 | ENCODES a protein that exhibits DNA binding (ortholog); SUMO ligase activity (ortholog); SUMO transferase activity (ortholog); INVOLVED IN central nervous system development (ortholog); hair follicle development (ortholog); limb epidermis development (ortholog); PARTICIPATES IN ataxia telangiectasia -mutated (ATM) signaling pathway; Jak-Stat signaling pathway; type II interferon signaling pathway; FOUND IN cytoplasm (ortholog); nuclear matrix (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 9197032 | 9210557 | Rat | 141 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560766 | Pid1 | phosphotyrosine interaction domain containing 1 | INVOLVED IN cellular response to cytokine stimulus (ortholog); cellular response to fatty acid (ortholog); cellular response to interleukin-6 (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol | 9 | 92732471 | 92951168 | Rat | 201 | old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1307205 | Pigp | phosphatidylinositol glycan anchor biosynthesis, class P | ENCODES a protein that exhibits phosphatidylinositol N-acetylglucosaminyltransferase activity (ortholog); INVOLVED IN GPI anchor biosynthetic process (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH developmental and epileptic encephalopathy (orth olog); developmental and epileptic encephalopathy 55 (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil | 11 | 47152601 | 47158766 | Rat | 101 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359535 | Pigq | phosphatidylinositol glycan anchor biosynthesis, class Q | ENCODES a protein that exhibits phosphatidylinositol N-acetylglucosaminyltransferase activity (ortholog); INVOLVED IN GPI anchor biosynthetic process (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH developmental and epileptic encephalopathy (orth olog); Developmental Disabilities (ortholog); epilepsy (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol | 10 | 15447080 | 15463088 | Rat | 93 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 11492645 | Pilrb-ps2 | paired immunoglobin-like type 2 receptor beta, pseudogene 2 | | 12 | 24408649 | 24418268 | Rat | | old_protein_id | gene, pseudo, MODEL [RefSeq] |
| 1559588 | Pilrb2l4 | paired immunoglobin like type 2 receptor beta 2 like 4 | FOUND IN cell periphery (inferred); membrane (inferred); INTERACTS WITH oxaliplatin; topotecan | 12 | 22512512 | 22518410 | Rat | 7 | UniProt | gene, protein-coding, MODEL [RefSeq] |
| 1308747 | Pimreg | PICALM interacting mitotic regulator | FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione | 10 | 57168136 | 57173713 | Rat | 118 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310299 | Pin1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | ENCODES a protein that exhibits beta-catenin binding (ortholog); cis-trans isomerase activity (ortholog); cytoskeletal motor activity (ortholog); INVOLVED IN negative regulation of neuron apoptotic process; positive regulation of cell growth involved in cardiac muscle cell development; positive regu lation of neuron apoptotic process; PARTICIPATES IN altered p53 signaling pathway; p53 signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH asthma; Experimental Mammary Neoplasms; secondary hyperparathyroidism; FOUND IN ciliary basal body (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 8 | 27465538 | 27477016 | Rat | 186 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311347 | Pipox | pipecolic acid and sarcosine oxidase | ENCODES a protein that exhibits L-pipecolate oxidase activity (ortholog); sarcosine oxidase activity (ortholog); INVOLVED IN L-lysine catabolic process to acetyl-CoA via L-pipecolate (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; hyperlysine mia pathway; ASSOCIATED WITH peroxisomal disease (ortholog); FOUND IN peroxisome (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 63267946 | 63281556 | Rat | 144 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305003 | Pknox1 | PBX/knotted 1 homeobox 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN angiogenesis (ortholog); camera-type eye development (ortholog); erythrocyte differentiation (ortholog); FOUND IN cytopl asm (ortholog); nucleus (ortholog); transcription regulator complex (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; cadmium dichloride | 20 | 9664120 | 9706328 | Rat | 89 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309862 | Pla2g2d | phospholipase A2, group IID | ENCODES a protein that exhibits A2-type glycerophospholipase activity (ortholog); calcium-dependent phospholipase A2 activity (ortholog); heparan sulfate proteoglycan binding (ortholog); INVOLVED IN CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (ortholog); negative regula tion of T cell activation (ortholog); negative regulation of T cell proliferation (ortholog); PARTICIPATES IN glycerophospholipid metabolic pathway; alpha-linolenic acid metabolic pathway; arachidonic acid metabolic pathway; FOUND IN extracellular region (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 156299374 | 156305816 | Rat | 114 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308102 | Plac8 | placenta associated 8 | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); defense response to bacterium (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH glucose intolerance; Insulin Resistance; Chlamydiaceae Infections (ortho log); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 14 | 9356950 | 9378586 | Rat | 179 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309567 | Plppr5 | phospholipid phosphatase related 5 | INVOLVED IN positive regulation of filopodium assembly (ortholog); positive regulation of neuron projection development (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 208143058 | 208422836 | Rat | 46 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359107 | Plscr2 | phospholipid scramblase 2 | ENCODES a protein that exhibits phospholipid scramblase activity (inferred); INVOLVED IN cellular response to lipopolysaccharide (inferred); plasma membrane phospholipid scrambling (inferred); FOUND IN cytoplasm (inferred); membrane (inferred); nucleus (inferred); INTERACTS WITH 17beta-estradiol; 2, 3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 8 | 101689202 | 101725726 | Rat | 30 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1305962 | Plxdc2 | plexin domain containing 2 | FOUND IN nuclear body (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 17 | 84077793 | 84502831 | Rat | 113 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310897 | Pmm1 | phosphomannomutase 1 | ENCODES a protein that exhibits phosphomannomutase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); mannose metabolic process (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH GLOBAL DEVELOPMENTAL DELAY, ABSENT OR HYPOPLASTIC CORPUS CALLOSUM, AND DYSMORPHIC FACIES (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); neuronal cell body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 7 | 115346767 | 115357137 | Rat | 125 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309366 | Pmm2 | phosphomannomutase 2 | ENCODES a protein that exhibits phosphomannomutase activity (ortholog); INVOLVED IN GDP-D-mannose biosynthetic process from fructose-6-phosphate (ortholog); GDP-mannose biosynthetic process (ortholog); GDP-mannose biosynthetic process from mannose (ortholog); PARTICIPATES IN amino sugar metabolic pa thway; fructose and mannose metabolic pathway; nucleotide sugar metabolic pathway; ASSOCIATED WITH cerebellar ataxia (ortholog); cerebellar hypoplasia (ortholog); cerebral palsy (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); neuronal cell body (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 7468371 | 7489574 | Rat | 138 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310812 | Pmvk | phosphomevalonate kinase | ENCODES a protein that exhibits phosphomevalonate kinase activity; ATP binding (ortholog); INVOLVED IN isopentenyl diphosphate biosynthetic process, mevalonate pathway; cholesterol biosynthetic process (ortholog); cholesterol biosynthetic process via desmosterol (ortholog); PARTICIPATES IN alendrona te pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH genetic disease (ortholog); porokeratosis (ortholog); Porokeratosis 1, Multiple Types (ortholog); FOUND IN cytosol (ortholog); peroxisome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 177174344 | 177184076 | Rat | 218 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303331 | Pnkp | polynucleotide kinase 3'-phosphatase | ENCODES a protein that exhibits ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity (ortholog); polynucleotide 3'-phosphatase activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN DNA damage response (ortholog); DNA repair (ortholog); double-stra nd break repair via nonhomologous end joining (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH ataxia-oculomotor apraxia 4 (ortholog); Charcot-Marie-Tooth disease type 2B2 (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 1 | 104476801 | 104483409 | Rat | 147 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305815 | Podxl2 | podocalyxin-like 2 | INVOLVED IN leukocyte tethering or rolling (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 122863476 | 122895318 | Rat | 65 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304684 | Poglut2 | protein O-glucosyltransferase 2 | ENCODES a protein that exhibits UDP-glucosyltransferase activity (ortholog); UDP-xylosyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via glucose (ortholog); FOUND IN endoplasmic reticulum lumen (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol ; 3-chloropropane-1,2-diol; bisphenol A | 9 | 53748484 | 53801453 | Rat | 75 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1308519 | Pold4 | DNA polymerase delta 4, accessory subunit | INVOLVED IN DNA-templated DNA replication; positive regulation of endothelial cell proliferation (ortholog); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; base excision repair pathway; ASSOCIATED WITH intellectual disability (ortholog); FOUND IN nucleus (ortholog); INT ERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 1 | 210956110 | 210957863 | Rat | 115 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308247 | Polm | DNA polymerase mu | ENCODES a protein that exhibits DNA binding (inferred); DNA polymerase activity (inferred); DNA-directed DNA polymerase activity (inferred); INVOLVED IN B cell differentiation (ortholog); somatic hypermutation of immunoglobulin genes (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; FOUND IN nucleoplasm (ortholog); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 7,12-dimethyltetraphene; acetamide | 14 | 84921039 | 84930649 | Rat | 86 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309689 | Polr1c | RNA polymerase I and III subunit C | ENCODES a protein that exhibits DNA binding (inferred); DNA-directed RNA polymerase activity (inferred); protein dimerization activity (inferred); INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase III (ortholog); transcription elongation by RNA p olymerase I (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase III transcription pathway; purine metabolic pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); genetic disease (ortholog); Hearing Loss (ortholog); FOUND IN cytoplasm (ortholog); fibrillar center (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene | 9 | 22233318 | 22237430 | Rat | 129 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564358 | Polr1d | RNA polymerase I and III subunit D | INVOLVED IN termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase III (ortholog); transcription elongation by RNA polymerase I (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase III transcription pathway; ASSOCIATED WITH Animal Di sease Models (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN RNA polymerase I complex (ortholog); RNA polymerase III complex (ortholog); INTERACTS WITH amphetamine; atrazine; bisphenol A | 12 | 13084505 | 13118069 | Rat | 94 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565773 | Polr1e | RNA polymerase I subunit E | ENCODES a protein that exhibits RNA polymerase I general transcription initiation factor binding (ortholog); INVOLVED IN nucleolar large rRNA transcription by RNA polymerase I (ortholog); RNA polymerase I preinitiation complex assembly (ortholog); transcription elongation by RNA polymerase I (orthol og); PARTICIPATES IN RNA polymerase I transcription pathway; purine metabolic pathway; pyrimidine metabolic pathway; FOUND IN fibrillar center (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 64075123 | 64090900 | Rat | 102 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306935 | Polr2c | RNA polymerase II subunit C | ENCODES a protein that exhibits DNA binding (inferred); DNA-directed RNA polymerase activity (inferred); protein dimerization activity (inferred); INVOLVED IN transcription by RNA polymerase II (ortholog); transcription elongation by RNA polymerase II (ortholog); transcription initiation at RNA poly merase II promoter (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; Huntington's disease pathway; purine metabolic pathway; ASSOCIATED WITH Deafness (ortholog); hereditary breast ovarian cancer syndrome (ortholog); infertility (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol; 2,4-dinitrotoluene | 19 | 10164148 | 10170930 | Rat | 103 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311816 | Polr3d | RNA polymerase III subunit D | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN positive regulation of innate immune response (ortholog); positive regulation of interferon-beta production (ortholog); termination of RNA polymerase III transcription (ortholog); PARTICIPATES IN RNA polymerase III transcripti on pathway; purine metabolic pathway; pyrimidine metabolic pathway; FOUND IN nucleoplasm (ortholog); RNA polymerase III complex (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 15 | 51921283 | 51925952 | Rat | 92 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305889 | Polr3h | RNA polymerase III subunit H | ENCODES a protein that exhibits DNA-directed RNA polymerase activity (ortholog); INVOLVED IN nucleobase-containing compound metabolic process (ortholog); termination of RNA polymerase III transcription (ortholog); transcription by RNA polymerase III (ortholog); PARTICIPATES IN RNA polymerase III tra nscription pathway; purine metabolic pathway; pyrimidine metabolic pathway; ASSOCIATED WITH primary ovarian insufficiency (ortholog); FOUND IN centrosome (ortholog); nucleoplasm (ortholog); RNA polymerase III complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol | 7 | 115309571 | 115319881 | Rat | 99 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359470 | Poteg | POTE ankyrin domain family, member G | INTERACTS WITH aflatoxin B1 (ortholog); benzo[e]pyrene (ortholog); calcitriol (ortholog) | 16 | 71191509 | 71373328 | Rat | 9 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303221 | Ppic | peptidylprolyl isomerase C | ENCODES a protein that exhibits peptidyl-prolyl cis-trans isomerase activity (ortholog); INVOLVED IN protein folding (inferred); ASSOCIATED WITH Stomach Neoplasms (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 18 | 49040690 | 49053296 | Rat | 143 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311411 | Ppie | peptidylprolyl isomerase E | ENCODES a protein that exhibits mRNA binding (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); poly(A) binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); positive regulation of viral genome replication (ortholog); regulation of DNA-templated transcription ( ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,4-dibromophenyl 2,4,5-tribromophenyl ether | 5 | 140691285 | 140704347 | Rat | 92 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309119 | Ppil1 | peptidylprolyl isomerase like 1 | ENCODES a protein that exhibits disordered domain specific binding (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); INVOLVED IN embryonic brain development (ortholog); mRNA splicing, via spliceosome (ortholog); protein peptidyl-prolyl isomerization (ortholog); PARTICIPATES IN spl iceosome pathway; ASSOCIATED WITH genetic disease (ortholog); microcephaly (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 7303919 | 7323962 | Rat | 127 | UniProt , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309484 | Ppil2 | peptidylprolyl isomerase like 2 | ENCODES a protein that exhibits peptidyl-prolyl cis-trans isomerase activity (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-ubiquitin ligase activity (ortholog); INVOLVED IN protein localization to plasma membrane (ortholog); protein polyubiquitination (ortholog); PARTICIPATES I N spliceosome pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 11 | 97401944 | 97424581 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305460 | Ppm1d | protein phosphatase, Mg2+/Mn2+ dependent, 1D | ENCODES a protein that exhibits mitogen-activated protein kinase binding (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN cellular response to starvation; DNA damage response, signal transduction by p53 class mediator (ortholog); DNA methylation-dependent constitutiv e heterochromatin formation (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; p38 MAPK signaling pathway; p53 signaling pathway; ASSOCIATED WITH Brain Stem Neoplasms (ortholog); breast cancer (ortholog); Breast Cancer, Familial (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Ampullosporin; bisphenol A | 10 | 70670026 | 70706030 | Rat | 214 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309049 | Ppp1r14bl | protein phosphatase 1, regulatory inhibitor subunit 14B like | ENCODES a protein that exhibits phosphatase inhibitor activity (inferred); protein phosphatase inhibitor activity (inferred); protein phosphatase regulator activity (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; C60 fullerene | 9 | 33027512 | 33029145 | Rat | 12 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563007 | Ppp1r2l1 | protein phosphatase 1, regulatory (inhibitor) subunit 2 like 1 | ENCODES a protein that exhibits protein phosphatase inhibitor activity (inferred); INVOLVED IN regulation of signal transduction (inferred) | 10 | 55119291 | 55123449 | Rat | 5 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309628 | Prkcsh | PRKCSH beta subunit of glucosidase II | ENCODES a protein that exhibits protein-containing complex binding; calcium ion binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN in utero embryonic development (ortholog); liver development (ortholog); N-glycan processing (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH genetic disease (ortholog); hepatitis B (ortholog); liver disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); glucosidase II complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; bisphenol A | 8 | 28810836 | 28822503 | Rat | 127 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1582762 | Prl3d2 | prolactin family 3, subfamily D member 2 | ENCODES a protein that exhibits hormone activity (inferred); metal ion binding (inferred); INVOLVED IN signal transduction (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; copper atom | 17 | 38251180 | 38257209 | Rat | 20 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1306618 | Prnd | prion like protein doppel | ENCODES a protein that exhibits copper ion binding (ortholog); INVOLVED IN acrosome reaction (ortholog); intracellular copper ion homeostasis (ortholog); single fertilization (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl- 2-thiouracil; bisphenol A | 3 | 139666383 | 139671647 | Rat | 82 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308179 | Prorsd1 | prolyl-tRNA synthetase associated domain containing 1 | ENCODES a protein that exhibits aminoacyl-tRNA deacylase activity (inferred); INVOLVED IN aminoacyl-tRNA metabolism involved in translational fidelity (inferred); tRNA metabolic process (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; caffeine | 14 | 107458910 | 107461179 | Rat | 55 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565712 | Proser3 | proline and serine rich 3 | FOUND IN centrosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 94920802 | 94934126 | Rat | 38 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311589 | Prr15 | proline rich 15 | INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 4 | 84762357 | 84765403 | Rat | 84 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302947 | Prss59 | protease, serine 59 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN positive regulation of reproductive process (inferred); proteolysis (inferred); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH Butylbenzyl pht halate (ortholog); titanium dioxide (ortholog) | 4 | 70730890 | 70751798 | Rat | 16 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310177 | Prtfdc1 | phosphoribosyl transferase domain containing 1 | ENCODES a protein that exhibits hypoxanthine phosphoribosyltransferase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN GMP catabolic process (ortholog); guanine salvage (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Mouth Neoplasms (ortholog); Ova rian Neoplasms (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 17 | 88457872 | 88563109 | Rat | 76 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304898 | Prtn3 | proteinase 3 | ENCODES a protein that exhibits enzyme binding (ortholog); serine-type endopeptidase activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell-cell junction maintenance (ortholog); mature conventional dendritic cell differentiation (ortholog); membrane protein ectodomain proteolys is (ortholog); ASSOCIATED WITH chronic myeloid leukemia (ortholog); granulomatosis with polyangiitis (ortholog); FOUND IN azurophil granule lumen (ortholog); cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH acrylamide; ammonium chloride; bisphenol A | 7 | 10472750 | 10482037 | Rat | 111 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563849 | Psg16 | pregnancy specific glycoprotein 16 | INTERACTS WITH bisphenol A; C60 fullerene; fenvalerate | 1 | 86934375 | 86949854 | Rat | 3 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1311470 | Psmd3 | proteasome 26S subunit, non-ATPase 3 | ENCODES a protein that exhibits enzyme regulator activity (inferred); INVOLVED IN regulation of AMPA receptor activity; PARTICIPATES IN ubiquitin/proteasome degradation pathway; ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); FOUND IN synaptic vesicle; cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 84139249 | 84151879 | Rat | 108 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306996 | Psme3 | proteasome activator subunit 3 | ENCODES a protein that exhibits endopeptidase activator activity (ortholog); identical protein binding (ortholog); MDM2/MDM4 family protein binding (ortholog); INVOLVED IN negative regulation of extrinsic apoptotic signaling pathway (ortholog); regulation of proteasomal protein catabolic process (or tholog); PARTICIPATES IN antigen processing and presentation pathway; hepatitis C pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 86757933 | 86765719 | Rat | 117 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307433 | Psme3ip1 | proteasome activator subunit 3 interacting protein 1 | INVOLVED IN negative regulation of proteasomal protein catabolic process (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; Brodifacoum; glyphosate | 19 | 10407382 | 10436029 | Rat | 30 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307557 | Pstpip1 | proline-serine-threonine phosphatase-interacting protein 1 | ENCODES a protein that exhibits actin binding (ortholog); identical protein binding (ortholog); protein phosphatase binding (ortholog); INVOLVED IN cell adhesion (inferred); endocytosis (inferred); immune system process (inferred); PARTICIPATES IN NOD-like receptor signaling pathway; ASSOCIATED WITH acne (ortholog); autoinflammatory syndrome with cytopenia, hyperzincemia, and hypercalprotectinemia (ortholog); Behcet's disease (ortholog); FOUND IN actomyosin contractile ring (ortholog); cleavage furrow (ortholog); cytosol (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 8 | 65395328 | 65434616 | Rat | 123 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308687 | Ptp4a3 | protein tyrosine phosphatase 4A3 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); endothelial cell migration (ortholog); Notch signaling pathway (ort holog); ASSOCIATED WITH Colonic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide | 7 | 107518220 | 107549949 | Rat | 113 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308354 | Ptpa | protein phosphatase 2 phosphatase activator | ENCODES a protein that exhibits ATP binding (ortholog); phosphatase binding (ortholog); phosphoprotein phosphatase activity (ortholog); INVOLVED IN positive regulation of apoptotic process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Disease Progression (ortholog); Parkinson's disease 25 (ortholog); Stomach Neoplasms (ortholog); FOUND IN ATPase complex (ortholog); calcium channel complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 3 | 34087637 | 34118100 | Rat | 118 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559601 | Ptprcap | protein tyrosine phosphatase, receptor type, C-associated protein | FOUND IN plasma membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene | 1 | 210878593 | 210880752 | Rat | 60 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307108 | Pwwp2b | PWWP domain containing 2B | ENCODES a protein that exhibits NuRD complex binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); positive regulation of transcription elongation by RNA polymerase II (ortholog); regulation of cold-induced thermogenesis (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); FO UND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; amitrole | 1 | 203470172 | 203489575 | Rat | 82 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305759 | Pxn | paxillin | ENCODES a protein that exhibits integrin binding; protein kinase binding; protein-containing complex binding; INVOLVED IN response to peptide; branching morphogenesis of an epithelial tube (ortholog); cell migration (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; i nsulin-like growth factor signaling pathway; integrin mediated signaling pathway; ASSOCIATED WITH Experimental Melanoma (ortholog); lung non-small cell carcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN focal adhesion; cell leading edge (ortholog); cell-cell junction (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 12 | 46721546 | 46768706 | Rat | 219 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308535 | Pygo2 | pygopus family PHD finger 2 | ENCODES a protein that exhibits chromatin binding (ortholog); histone acetyltransferase regulator activity (ortholog); histone binding (ortholog); INVOLVED IN brain development (ortholog); canonical Wnt signaling pathway (ortholog); developmental growth (ortholog); FOUND IN beta-catenin-TCF complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; allethrin; bisphenol A | 2 | 177147407 | 177152476 | Rat | 84 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311345 | Qng1 | Q-nucleotide N-glycosylase 1 | ENCODES a protein that exhibits queuosine nucleosidase activity (ortholog); INVOLVED IN nucleoside salvage (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; amitrole; bisphenol A | 17 | 6286801 | 6294400 | Rat | 52 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308128 | Qpctl | glutaminyl-peptide cyclotransferase-like | ENCODES a protein that exhibits glutaminyl-peptide cyclotransferase activity (ortholog); zinc ion binding (ortholog); FOUND IN Golgi apparatus (ortholog); INTERACTS WITH acrylamide; bisphenol A; flutamide | 1 | 87916771 | 87925843 | Rat | 51 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307067 | R3hdm4 | R3H domain containing 4 | ENCODES a protein that exhibits nucleic acid binding (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amitrole | 7 | 10441032 | 10448143 | Rat | 42 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308952 | Rab11fip3 | RAB11 family interacting protein 3 | ENCODES a protein that exhibits dynein light intermediate chain binding (ortholog); identical protein binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN early endosome to recycling endosome transport (ortholog); endocytic recycling (ortholog); Golgi to plasma membrane protein tra nsport (ortholog); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH epilepsy (ortholog); FOUND IN centrosome (ortholog); cleavage furrow (ortholog); endocytic vesicle membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol | 10 | 15507151 | 15591173 | Rat | 122 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1308447 | Rab25 | RAB25, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (ortholog); myosin V binding (ortholog); INVOLVED IN epithelial cell morphogenesis (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of epithelial cell migration (ortholog); ASSOCIATED WITH Charcot-Mari e-Tooth disease type 2 (ortholog); FOUND IN cytoplasmic vesicle (ortholog); plasma membrane (ortholog); pseudopodium (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 176298124 | 176304221 | Rat | 103 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305663 | Rab40b | Rab40b, member RAS oncogene family | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN cellular detoxification (ortholog); negative regulation of actin filament bundle assembly (ortholog); positive regulation of cell migration (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosi s (ortholog); FOUND IN cytosol (ortholog); lamellipodium (ortholog); lamellipodium membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 107129801 | 107157375 | Rat | 134 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306489 | Rab5b | RAB5B, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (ortholog); GDP binding (ortholog); GTP-dependent protein binding (ortholog); INVOLVED IN antigen processing and presentation (ortholog); endocytosis (ortholog); endosomal transport (ortholog); PARTICIPATES IN endocytosis pathway; Entamoebiasis path way; phagocytosis pathway; ASSOCIATED WITH Pulmonary Surfactant Metabolism Dysfunction 1 (ortholog); FOUND IN synaptic vesicle membrane; endocytic vesicle (ortholog); endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; bisphenol A | 7 | 1693971 | 1712936 | Rat | 121 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307095 | Rab5c | RAB5C, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (ortholog); GDP binding (ortholog); GTPase activity (ortholog); INVOLVED IN endocytosis (ortholog); endosomal transport (ortholog); endosome organization (ortholog); PARTICIPATES IN endocytosis pathway; Entamoebiasis pathway; phagocytosis pathway; A SSOCIATED WITH autosomal recessive intellectual developmental disorder 41 (ortholog); genetic disease (ortholog); FOUND IN synaptic vesicle membrane; endocytic vesicle (ortholog); endosome (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 86142872 | 86166449 | Rat | 121 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307752 | Rab5if | RAB5 interacting factor | INVOLVED IN mitochondrial respirasome assembly (ortholog); multi-pass transmembrane protein insertion into ER membrane (ortholog); ASSOCIATED WITH craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 2 (ortholog); FOUND IN endoplasmic reticulum membrane (ortho log); mitochondrion (ortholog); multi-pass translocon complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | 3 | 165818060 | 165828071 | Rat | 71 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307568 | Rac2 | Rac family small GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); protein kinase regulator activity (ortholog); INVOLVED IN actin cytoskeleton organization; bone resorption; actin filament organization (ortholog); PARTICIPATES IN B cell receptor signaling pathway; ceramide signalin g pathway; chemokine mediated signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Chronic Periodontitis (ortholog); Disease Progression (ortholog); FOUND IN actin filament (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 111981825 | 112009201 | Rat | 274 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309899 | Rad23a | RAD23 nucleotide excision repair protein A | ENCODES a protein that exhibits histone H4K20 demethylase activity (ortholog); kinase binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN DNA damage response (ortholog); nucleotide-excision repair (ortholog); positive regulation of cell cycle (ortholog); PARTICIPATES IN nucleotide excision repair pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 19 | 40219235 | 40225543 | Rat | 166 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563603 | Rad51 | RAD51 recombinase | ENCODES a protein that exhibits ATP binding (ortholog); chromatin binding (ortholog); DNA polymerase binding (ortholog); INVOLVED IN cellular response to cisplatin; cellular response to gamma radiation; double-strand break repair via homologous recombination; PARTICIPATES IN homologous recombination pathway of double-strand break repair; ceramide signaling pathway; pancreatic cancer pathway; ASSOCIATED WITH cardiomyopathy; Experimental Liver Neoplasms; hypertension; FOUND IN chromatin (ortholog); chromosome (ortholog); chromosome, telomeric region (ortholog); INTERACTS WITH (-)-demecolcine; 1,4-dioxane; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile | 3 | 126554210 | 126578888 | Rat | 478 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306944 | Rad51d | RAD51 paralog D | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); ATP-dependent DNA damage sensor activity (ortholog); four-way junction DNA binding (ortholog); INVOLVED IN chromosome organization (ortholog); DNA damage response (ortholog); DNA strand invasion (ortholog); PARTICIPATE S IN homologous recombination pathway of double-strand break repair; ASSOCIATED WITH breast cancer (ortholog); Chromosome Deletion (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN centrosome (ortholog); chromosome, telomeric region (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 68303350 | 68322002 | Rat | 143 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310600 | Rad54l | RAD54 like | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); ATP-dependent DNA/DNA annealing activity (ortholog); INVOLVED IN chromosome organization (ortholog); determination of adult lifespan (ortholog); DNA damage response (ortholog); PARTICIPATES IN homologous recombination pathway of double-strand break repair; ASSOCIATED WITH breast cancer (ortholog); Breast Cancer, Familial (ortholog); breast ductal carcinoma (ortholog); FOUND IN nucleoplasm (ortholog); protein-containing complex (ortholog); site of double-strand break (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; acetamide | 5 | 134812158 | 134841821 | Rat | 154 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308344 | Raet1c | retinoic acid early transcript gamma | | 1 | 3605103 | 3607930 | Rat | | old_protein_id | gene, protein-coding, MODEL [RefSeq] |
| 1311118 | Raet1e | retinoic acid early transcript 1E | ENCODES a protein that exhibits natural killer cell lectin-like receptor binding (ortholog); INVOLVED IN natural killer cell mediated cytotoxicity (ortholog); positive regulation of natural killer cell mediated cytotoxicity (ortholog); T cell mediated cytotoxicity (ortholog); FOUND IN cytosol (ortho log); focal adhesion (ortholog); INTERACTS WITH cadmium dichloride; endosulfan; methoxychlor | 1 | 3474487 | 3476431 | Rat | 65 | old_protein_id | gene, protein-coding, MODEL [RefSeq] |
| 1308785 | Raet1l | retinoic acid early transcript 1L | ENCODES a protein that exhibits natural killer cell lectin-like receptor binding (inferred); INVOLVED IN positive regulation of natural killer cell mediated cytotoxicity; ASSOCIATED WITH Transplant Rejection; FOUND IN plasma membrane (inferred); side of membrane (inferred) | 1 | 3799823 | 3804799 | Rat | 14 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1302985 | Ralgdsl2 | ral guanine nucleotide dissociation stimulator like 2 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN negative regulation of cardiac muscle cell apoptotic process (ortholog); positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); regulation of Ral protein signal transduction (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 20 | 4950379 | 4958315 | Rat | 74 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305844 | Ralyl | RALY RNA binding protein-like | ENCODES a protein that exhibits identical protein binding (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; atrazine | 2 | 89390212 | 90181681 | Rat | 48 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309509 | Rarres1 | retinoic acid receptor responder 1 | ENCODES a protein that exhibits metalloendopeptidase inhibitor activity (inferred); peptidase inhibitor activity (inferred); INVOLVED IN negative regulation of cell population proliferation (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); follicular lymphoma (ortholog); Stomach N eoplasms (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 2 | 154059761 | 154094021 | Rat | 167 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309874 | Rarres2 | retinoic acid receptor responder 2 | ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN cellular response to insulin stimulus; positive regulation of systemic arterial blood pressure; response to activity; ASSOCIATED WITH decreased circulating aspartate transaminase level; decreased heart rate; decreased mean systemic arterial blood pressure; ASSOCIATED WITH metabolic dysfunction-associated steatotic liver disease; obesity; polycystic ovary syndrome; FOUND IN extracellular space; extracellular matrix (ortholog); extracellular region (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 4 | 78853450 | 78856652 | Rat | 224 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305419 | Rars2 | arginyl-tRNA synthetase 2, mitochondrial | ENCODES a protein that exhibits arginine-tRNA ligase activity (ortholog); INVOLVED IN arginyl-tRNA aminoacylation (inferred); gene expression (inferred); translation (inferred); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase defici ency pathway; ASSOCIATED WITH cerebellar hypoplasia (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; flutamide | 5 | 53976808 | 54029715 | Rat | 92 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359383 | Rassf1 | Ras association domain family member 1 | ENCODES a protein that exhibits identical protein binding (ortholog); small GTPase binding (ortholog); INVOLVED IN DNA damage response (ortholog); positive regulation of protein ubiquitination (ortholog); protein stabilization (ortholog); PARTICIPATES IN p53 signaling pathway; non-small cell lung ca rcinoma pathway; urinary bladder cancer pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Mammary Neoplasms (ortholog); bladder disease (ortholog); FOUND IN microtubule cytoskeleton (ortholog); nucleus (ortholog); INTERACTS WITH (S)-colchicine; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17beta-estradiol | 8 | 117103665 | 117114805 | Rat | 232 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306891 | Rbm4 | RNA binding motif protein 4 | ENCODES a protein that exhibits cyclin binding (ortholog); miRNA binding (ortholog); mRNA 3'-UTR binding (ortholog); INVOLVED IN cap-independent translational initiation (ortholog); circadian regulation of gene expression (ortholog); circadian regulation of translation (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; chlorpyrifos | 1 | 211507845 | 211516907 | Rat | 122 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1304813 | Rbms2 | RNA binding motif, single stranded interacting protein 2 | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); FOUND IN ribonucleoprotein complex (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 7 | 1145240 | 1201690 | Rat | 54 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311826 | Rcan3 | RCAN family member 3 | ENCODES a protein that exhibits phosphatase binding (ortholog); troponin I binding (ortholog); INVOLVED IN calcium-mediated signaling (inferred); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 5 | 152934561 | 152955502 | Rat | 86 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359180 | Rchy1 | ring finger and CHY zinc finger domain containing 1 | ENCODES a protein that exhibits signaling receptor binding; p53 binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); protein autoubiquitination (ortholog); protein ubiquitination (or tholog); PARTICIPATES IN p53 signaling pathway; measles pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Brain Injuries; sciatic neuropathy; Disease Progression (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 14 | 16397533 | 16413286 | Rat | 119 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307468 | Rell1 | RELT-like 1 | INVOLVED IN positive regulation of p38MAPK cascade (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A | 14 | 44672121 | 44732081 | Rat | 92 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306560 | Rem1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (ortholog); T-tubule (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 3 | 161563984 | 161572478 | Rat | 52 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306220 | Rexo4 | RNA exonuclease 4 | ENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog); double-stranded DNA binding (ortholog); endonuclease activity (ortholog); INVOLVED IN DNA catabolic process (ortholog); DNA repair (ortholog); ASSOCIATED WITH Habitual Abortions (ortholog); FOUND IN nucleolus (ortholog); nucleopl asm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 3 | 30678729 | 30692376 | Rat | 96 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306832 | Rfc3 | replication factor C subunit 3 | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); DNA binding (ortholog); DNA clamp loader activity (ortholog); INVOLVED IN DNA replication (ortholog); DNA-templated DNA replication (ortholog); positive regulation of DNA-directed DNA polymerase activity (ortholog); PA RTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; DNA replication pathway; FOUND IN Ctf18 RFC-like complex (ortholog); DNA replication factor C complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 12 | 5836546 | 5847331 | Rat | 179 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310142 | Rfc4 | replication factor C subunit 4 | ENCODES a protein that exhibits DNA clamp loader activity (ortholog); enzyme binding (ortholog); single-stranded DNA helicase activity (ortholog); INVOLVED IN DNA-templated DNA replication (ortholog); positive regulation of DNA-directed DNA polymerase activity (ortholog); PARTICIPATES IN mismatch re pair pathway; nucleotide excision repair pathway; DNA replication pathway; ASSOCIATED WITH Animal Disease Models (ortholog); lung adenocarcinoma (ortholog); MORIMOTO-RYU-MALICDAN NEUROMUSCULAR SYNDROME (ortholog); FOUND IN Ctf18 RFC-like complex (ortholog); DNA replication factor C complex (ortholog); Elg1 RFC-like complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 11 | 91254273 | 91268727 | Rat | 185 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549748 | Rfk | riboflavin kinase | ENCODES a protein that exhibits riboflavin kinase activity (ortholog); INVOLVED IN apoptotic process (ortholog); positive regulation of NAD(P)H oxidase activity (ortholog); reactive oxygen species metabolic process (ortholog); PARTICIPATES IN riboflavin metabolic pathway; ASSOCIATED WITH Prostatic N eoplasms (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2-methoxyethanol | 1 | 224226632 | 224234185 | Rat | 122 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309362 | RGD1309362 | similar to interferon-inducible GTPase | ENCODES a protein that exhibits GTP binding (inferred); hydrolase activity (inferred); nucleotide binding (inferred); FOUND IN membrane (inferred); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 55943741 | 55969375 | Rat | 42 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309924 | Rhobtb2 | Rho-related BTB domain containing 2 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN protein ubiquitination (ortholog); ubiquitin-dependent protein catabolic process (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 64 (ortholog); dystonia (ortholog); genetic disease (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1-nitropropane; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 51278024 | 51298209 | Rat | 121 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304965 | Rhoc | ras homolog family member C | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN apical junction assembly (ortholog); mitotic cytokinesis (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH breast cancer (ortholog); Myocardial Ischemia (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cleavage furrow (ortholog); nucleus (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 2 | 194975586 | 194981637 | Rat | 200 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307023 | Rhot1 | ras homolog family member T1 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); calcium ion binding (ortholog); GDP binding (ortholog); INVOLVED IN establishment of mitochondrion localization by microtubule attachment; regulation of neurotransmitter secretion; regulation of organelle transport along microtubule ; PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH motor neuron disease (ortholog); FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH bisphenol A; copper atom; copper(0) | 10 | 65685687 | 65760682 | Rat | 100 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563789 | Rhoxf12 | Rhox homeobox family member 12 | ENCODES a protein that exhibits DNA binding (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A | X | 121756211 | 121763630 | Rat | 8 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1561047 | Rhoxf8 | Rhox homeobox family member 8 | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN regulation of gene expression (ortholog); spermatogenesis (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH bisphenol A; genistein; all-trans-retinoic acid (ortholog) | X | 121450408 | 121454031 | Rat | 29 | UniProt , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563844 | Rhoxf9 | Rhox homeobox family member 9 | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 4,4'-sulfonyldiphenol (ortholog); 5-aza-2'-deoxycytidine (ortholog) | X | 121507522 | 121510373 | Rat | 24 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311588 | Riok2 | RIO kinase 2 | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); kinase activity (inferred); INVOLVED IN maturation of SSU-rRNA (ortholog); positive regulation of ribosomal small subunit export from nucleus (ortholog); positive regulation of rRNA processing (ortholog); PARTICIP ATES IN ribosome biogenesis pathway; FOUND IN cytoplasm (ortholog); preribosome, small subunit precursor (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bisphenol A | 1 | 66776215 | 66792480 | Rat | 102 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559832 | Rlim | ring finger protein, LIM domain interacting | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); obsolete negative regulation of DNA-binding transcription factor activity (ortholog); pro tein ubiquitination (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); genetic disease (ortholog); non-syndromic X-linked intellectual disability (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | X | 73048983 | 73070302 | Rat | 114 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311458 | Rmp64 | ribonuclease MRP subunit p64 | INVOLVED IN negative regulation of neuron differentiation (ortholog); positive regulation of Notch signaling pathway (ortholog); RNA processing (ortholog); ASSOCIATED WITH anauxetic dysplasia 3 (ortholog); microcephaly (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortho log); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 11 | 69464263 | 69476429 | Rat | 48 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359723 | Rnase11 | ribonuclease A family member 11 | ENCODES a protein that exhibits nucleic acid binding (inferred); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; bisphenol A | 15 | 26741732 | 26743718 | Rat | 21 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303020 | Rnase6 | ribonuclease A family member 6 | ENCODES a protein that exhibits RNA nuclease activity (ortholog); INVOLVED IN antibacterial humoral response (ortholog); antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH liver disease (ortholog ); toxic encephalopathy (ortholog); FOUND IN cytoplasmic vesicle (ortholog); extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 15 | 26827896 | 26830807 | Rat | 88 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359501 | Rnase9 | ribonuclease A family member 9 | ENCODES a protein that exhibits nucleic acid binding (inferred); INVOLVED IN positive regulation of flagellated sperm motility involved in capacitation (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; carbon nanotube; silicon dioxide | 15 | 26733051 | 26736605 | Rat | 24 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359693 | Rnf113a1 | ring finger protein 113A1 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); negative regulation of chemokine-mediated signaling pathway (ortholog); protein ubiquitination (ortholog); ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH MICROCEPHAL Y, ARTHROGRYPOSIS, AND STRUCTURAL BRAIN ANOMALIES (ortholog); nonphotosensitive trichothiodystrophy 5 (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); U2-type precatalytic spliceosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; chlormequat chloride | X | 121293621 | 121294844 | Rat | 64 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1306011 | Rnf126 | ring finger protein 126 | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN cytoplasm protein quality control by the ubiquitin-proteasome system (ortholog); negative regulation of epidermal growth factor receptor signaling pathway (o rtholog); positive regulation of double-strand break repair via homologous recombination (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 7 | 10590013 | 10597585 | Rat | 94 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1305252 | Rnf135 | ring finger protein 135 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); calcium ion binding (ortholog); GDP binding (ortholog); INVOLVED IN antiviral innate immune response (ortholog); free ubiquitin chain polymerization (ortholog); positive regulation of interferon-beta production (ortholog); ASSOCIATE D WITH autism spectrum disorder (ortholog); chromosome 17q11.2 deletion syndrome (ortholog); Growth Disorders (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); ribonucleoprotein complex (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; Monobutylphthalate | 10 | 65668441 | 65687671 | Rat | 123 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1309561 | Rnf145 | ring finger protein 145 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN membrane (inferred); INTERACTS WITH 1-benzylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 10 | 29507779 | 29552153 | Rat | 127 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308287 | Rnf32 | ring finger protein 32 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN aggresome (ortholog); cytosol (ortholog); endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Butylbenzyl phthalate | 4 | 6822700 | 6884411 | Rat | 50 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307376 | Rpa1 | replication protein A1 | ENCODES a protein that exhibits single-stranded DNA binding; chromatin binding (ortholog); chromatin-protein adaptor activity (ortholog); INVOLVED IN base-excision repair (ortholog); chromosome organization (ortholog); DNA damage response (ortholog); PARTICIPATES IN mismatch repair pathway; nucleoti de excision repair pathway; DNA replication pathway; ASSOCIATED WITH Chloracne (ortholog); Pulmonary Fibrosis and/or Bone Marrow Failure Syndrome, Telomere-Related, 6 (ortholog); FOUND IN DNA replication factor A complex; condensed chromosome (ortholog); condensed nuclear chromosome (ortholog); INTERACTS WITH (+)-schisandrin B; amphetamine; benzo[a]pyrene | 10 | 60647185 | 60698279 | Rat | 222 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1564890 | Rpe | ribulose-5-phosphate-3-epimerase | ENCODES a protein that exhibits carbohydrate binding; D-ribulose-phosphate 3-epimerase activity; monosaccharide binding; INVOLVED IN pentose-phosphate shunt; pentose-phosphate shunt, non-oxidative branch; carbohydrate metabolic process (ortholog); PARTICIPATES IN pentose phosphate pathway; ribose 5- phosphate isomerase deficiency pathway; transaldolase deficiency pathway; FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; buspirone | 9 | 75640867 | 75661009 | Rat | 93 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306906 | Rpf2 | ribosome production factor 2 homolog | ENCODES a protein that exhibits 5S rRNA binding (ortholog); INVOLVED IN protein localization to nucleolus (ortholog); regulation of signal transduction by p53 class mediator (ortholog); ribosomal large subunit biogenesis (ortholog); FOUND IN chromosome (ortholog); nucleolus (ortholog); INTERACTS WIT H (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 45184511 | 45205983 | Rat | 129 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560136 | Rpgr | retinitis pigmentosa GTPase regulator | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN cellular response to light stimulus (ortholog); cilium assembly (ortholog); eye photoreceptor cell development (ortholog); PARTICIPATES IN retinitis pigmentosa pathway; ASSOCIATED WITH Ciliary Motility Disorders (ortholog); cone dystrophy (ortholog); cone-rod dystrophy (ortholog); FOUND IN cell projection; centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; atrazine; bisphenol A | X | 15238961 | 15299004 | Rat | 173 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1309517 | Rpl22l1 | ribosomal protein L22 like 1 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); FOUND IN cytoplasm (inferred); ribonucleoprotein complex (inferred); ribosome (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 113683196 | 113685132 | Rat | 122 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304934 | Rpusd1 | RNA pseudouridine synthase domain containing 1 | ENCODES a protein that exhibits pseudouridine synthase activity (inferred); RNA binding (inferred); INVOLVED IN pseudouridine synthesis (inferred); RNA modification (inferred); ASSOCIATED WITH prostate cancer (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodi oxine; 2,3,7,8-Tetrachlorodibenzofuran | 10 | 15255806 | 15259730 | Rat | 39 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311760 | Rragc | Ras-related GTP binding C | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); GDP binding (ortholog); GTP binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICI PATES IN mTOR signaling pathway; ASSOCIATED WITH follicular lymphoma (ortholog); genetic disease (ortholog); LONG-OLSEN-DISTELMAIER SYNDROME (ortholog); FOUND IN cytoplasm (ortholog); FNIP-folliculin RagC/D GAP (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 5 | 141433014 | 141452546 | Rat | 136 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310793 | Rras2 | RAS related 2 | ENCODES a protein that exhibits GTPase activity (ortholog); INVOLVED IN positive regulation of cell migration (ortholog); Ras protein signal transduction (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Desbuquois dysplasia (ortholog); Experimental Live r Neoplasms (ortholog); genetic disease (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 177668143 | 177737551 | Rat | 183 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307881 | Rrp9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein | ENCODES a protein that exhibits U3 snoRNA binding (ortholog); INVOLVED IN ribosomal small subunit biogenesis (ortholog); rRNA processing (ortholog); ASSOCIATED WITH Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN box C/D methylation guide snoRNP complex (ortholog); nucleolus ( ortholog); small-subunit processome (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 115995119 | 116004832 | Rat | 113 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563246 | Rspo3 | R-spondin 3 | ENCODES a protein that exhibits frizzled binding (ortholog); heparin binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); blood vessel remodeling (ortholog); branching involved in labyrinthine layer morphogenesis (ortholog); PARTICIPATES IN Wnt signaling, c anonical pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); hepatocellular carcinoma (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; amitrole | 1 | 30112529 | 30197267 | Rat | 130 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359292 | RT1-CE10 | RT1 class I, locus CE10 | PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 3381377 | 3385052 | Rat | 30 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1359499 | RT1-T24-1 | RT1 class I, locus T24, gene 1 | INVOLVED IN antigen processing and presentation of peptide antigen via MHC class I (inferred); immune system process (inferred); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; FOUND IN lumenal side of endoplasmic reticulum me mbrane (inferred); membrane (inferred); MHC class I protein complex (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 2766304 | 2779680 | Rat | 30 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563384 | Rtn4ip1 | reticulon 4 interacting protein 1 | ENCODES a protein that exhibits NADH dehydrogenase (quinone) (non-electrogenic) activity (ortholog); NADPH dehydrogenase (quinone) activity (ortholog); INVOLVED IN regulation of dendrite development (ortholog); ubiquinone biosynthetic process (ortholog); ASSOCIATED WITH Developmental Disabilities (o rtholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrial outer membrane (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; alpha-Zearalanol | 20 | 48964903 | 49004235 | Rat | 93 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304704 | Rtraf | RNA transcription, translation and transport factor | ENCODES a protein that exhibits RNA binding (ortholog); RNA polymerase II complex binding (ortholog); INVOLVED IN negative regulation of protein kinase activity (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); tRNA splicing, via endonucleolytic cleavage and ligation (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); mitotic spindle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; ethanol | 15 | 4482699 | 4507115 | Rat | 60 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1565933 | Rtraf-ps2 | RNA transcription, translation and transport factor, pseudogene 2 | | 14 | 40099134 | 40145340 | Rat | | old_protein_id | gene, pseudo, VALIDATED [RefSeq] |
| 1305062 | Rwdd2b | RWD domain containing 2B | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 11 | 40152139 | 40166328 | Rat | 59 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311550 | Rxfp3 | relaxin family peptide receptor 3 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); INVOLVED IN phospholipase C-activating G protein-coupled receptor signaling pathway (ortholog); positive regulation of cytokinesis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS W ITH 6-propyl-2-thiouracil; acrylamide; amitrole | 2 | 61730376 | 61731806 | Rat | 38 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309356 | Rxylt1 | ribitol xylosyltransferase 1 | ENCODES a protein that exhibits ribitol beta-1,4-xylosyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via mannose (ortholog); ASSOCIATED WITH congenital muscular dystrophy-dystroglycanopathy type A10 (ortholog); genetic disease (ortholog); Walker-Warburg syndrome (ortho log); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acetamide | 7 | 59656274 | 59668140 | Rat | 94 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1565537 | Sap30bp | SAP30 binding protein | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (ortholog); INVOLVED IN regulation of mRNA splicing, via spliceosome (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN nuclear speck (ortholog); nucleoplasm (ortholog); nucleus (ortholog) ; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; fipronil | 10 | 101664714 | 101697430 | Rat | 77 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359540 | Sar1a | secretion associated, Ras related GTPase 1A | ENCODES a protein that exhibits amino acid sensor activity (ortholog); G protein activity (ortholog); INVOLVED IN cellular response to leucine starvation (ortholog); COPII vesicle coating (ortholog); COPII-coated vesicle cargo loading (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degr adation pathway; FOUND IN COPII vesicle coat (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum exit site (ortholog); INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 30166310 | 30178718 | Rat | 140 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560293 | Sash3 | SAM and SH3 domain containing 3 | INVOLVED IN homeostasis of number of cells within a tissue (ortholog); positive regulation of adaptive immune response (ortholog); positive regulation of B cell proliferation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); immunodeficiency 102 (ortholog); FOUND IN cytoplasm (ort holog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol | X | 132204717 | 132219421 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305561 | Satb1 | SATB homeobox 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN activated T cell proliferation (ortholog); CD4-positive, alpha-beta T cell differentiation (ortholog); CD8-positive, alpha-beta T cell differentiati on (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); autism spectrum disorder (ortholog); DEVELOPMENTAL DELAY WITH DYSMORPHIC FACIES AND DENTAL ANOMALIES (ortholog); FOUND IN chromatin (ortholog); heterochromatin (ortholog); nuclear body (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione | 9 | 4916958 | 5010359 | Rat | 192 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562305 | Sbsn | suprabasin | FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride | 1 | 95106390 | 95133448 | Rat | 79 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562708 | Scfd2 | sec1 family domain containing 2 | INVOLVED IN protein transport (inferred); vesicle-mediated transport (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; flutamide | 14 | 34037392 | 34369423 | Rat | 101 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560154 | Scgb2b24 | secretoglobin, family 2B, member 24 | FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH bisphenol A | 1 | 95708871 | 95709783 | Rat | 3 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1564790 | Scgb3a2 | secretoglobin, family 3A, member 2 | ASSOCIATED WITH allergic rhinitis (ortholog); Lung Neoplasms (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH bisphenol A; cefaloridine; 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog) | 18 | 36183745 | 36186667 | Rat | 70 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359454 | Sdhc | succinate dehydrogenase complex subunit C | ENCODES a protein that exhibits heme binding (ortholog); protein-membrane adaptor activity (ortholog); succinate dehydrogenase (quinone) activity (ortholog); INVOLVED IN tricarboxylic acid cycle (ortholog); PARTICIPATES IN citric acid cycle pathway; electron transport chain pathway; fumaric aciduria pathway; ASSOCIATED WITH breast cancer (ortholog); Carney Triad (ortholog); Carney-Stratakis syndrome (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone | 13 | 86077133 | 86098025 | Rat | 190 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309103 | Sec23a | SEC23 A, COPII component | ENCODES a protein that exhibits zinc ion binding (ortholog); INVOLVED IN COPII-coated vesicle cargo loading (ortholog); protein localization to plasma membrane (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH craniolenticulosutural dysplasia (ortholog ); osteoarthritis (ortholog); FOUND IN COPII vesicle coat (ortholog); COPII-coated ER to Golgi transport vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 82393699 | 82442594 | Rat | 148 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304997 | Sec61b | SEC61 translocon subunit beta | ENCODES a protein that exhibits epidermal growth factor binding (ortholog); ribosome binding (ortholog); INVOLVED IN ERAD pathway (ortholog); retrograde protein transport, ER to cytosol (ortholog); SRP-dependent cotranslational protein targeting to membrane, translocation (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; phagocytosis pathway; FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); endoplasmic reticulum quality control compartment (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 66569184 | 66577394 | Rat | 125 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309343 | Sema3c | semaphorin 3C | ENCODES a protein that exhibits semaphorin receptor binding (ortholog); INVOLVED IN axon guidance (ortholog); blood vessel remodeling (ortholog); cardiac endothelial to mesenchymal transition (ortholog); ASSOCIATED WITH High Myopia (ortholog); Persistent Truncus Arteriosus (ortholog); rheumatoid art hritis (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 4 | 18538452 | 18702453 | Rat | 221 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304636 | Sema4a | semaphorin 4A | ENCODES a protein that exhibits semaphorin receptor binding (inferred); INVOLVED IN axonogenesis (ortholog); negative regulation of angiogenesis (ortholog); positive regulation of excitatory synapse assembly (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colonic Polyp s (ortholog); colorectal cancer (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acetamide | 2 | 176194248 | 176215752 | Rat | 135 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303230 | Senp18 | Sumo1/sentrin/SMT3 specific peptidase 18 | ENCODES a protein that exhibits cysteine-type peptidase activity (inferred); hydrolase activity (inferred); peptidase activity (inferred); INVOLVED IN proteolysis (inferred); regulation of macromolecule metabolic process (inferred); regulation of primary metabolic process (inferred); PARTICIPATES IN RNA transport pathway; Wnt signaling pathway; INTERACTS WITH chlorpyrifos; glyphosate; progesterone | 4 | 162752390 | 162753817 | Rat | 16 | UniProt , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311396 | Serinc2 | serine incorporator 2 | ENCODES a protein that exhibits acetyltransferase activator activity; phospholipid scramblase activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN phosphatidylserine metabolic process; plasma membrane phospholipid scrambling (ortholog); sphingolipid metabolic process ( ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 147876477 | 147898797 | Rat | 123 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308390 | Serinc3 | serine incorporator 3 | ENCODES a protein that exhibits molecular carrier activity (ortholog); phospholipid scramblase activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); phosphatidylserine metabolic process (ortholog); plasma membrane phospholipi d scrambling (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN Golgi apparatus (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione | 3 | 172721208 | 172749853 | Rat | 120 | old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310452 | Serpinb6b | serine (or cysteine) peptidase inhibitor, clade B, member 6b | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); PARTICIPATES IN Entamoebiasis pathway; FOUND IN cytoplasm (inferred); extracellular space (inferred); nucleus (inferred); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetra chlorodibenzodioxine; 3-chloropropane-1,2-diol | 17 | 31666587 | 31684222 | Rat | 36 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549730 | Serpinb9 | serpin family B member 9 | ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process (ortholog); protease binding (ortholog); serine-type endopeptidase inhibitor activity (ortholog); INVOLVED IN acute inflammatory response to antigenic stimulus (ortholog); cellular response t o estrogen stimulus (ortholog); defense response to bacterium (ortholog); PARTICIPATES IN Entamoebiasis pathway; ASSOCIATED WITH Chloracne (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular space (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 17 | 31628887 | 31652003 | Rat | 202 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307404 | Serpinc1 | serpin family C member 1 | ENCODES a protein that exhibits heparin binding; serine-type endopeptidase inhibitor activity; identical protein binding (ortholog); INVOLVED IN acute inflammatory response to antigenic stimulus; lactation; response to nutrient; PARTICIPATES IN coagulation cascade pathway; enoxaparin pharmacodynamic s pathway; fondaparinux pharmacodynamics pathway; ASSOCIATED WITH increased susceptibility to kidney reperfusion injury; ASSOCIATED WITH Endotoxemia; Experimental Arthritis; Experimental Diabetes Mellitus; FOUND IN extracellular space; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 13 | 75790558 | 75804826 | Rat | 218 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306692 | Serpinf2 | serpin family F member 2 | ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity (ortholog); protease binding (ortholog); INVOLVED IN negative regulation of fibrinolysis; blood vessel morphogenesis (ortholog); collagen fibril organization (ortholog); PARTICIPATES IN fib rinolysis pathway; coagulation cascade pathway; complement system pathway; ASSOCIATED WITH acute necrotizing pancreatitis; familial hyperlipidemia; alpha-2-plasmin inhibitor deficiency (ortholog); FOUND IN extracellular space; cell surface (ortholog); fibrinogen complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | 10 | 60770698 | 60778782 | Rat | 188 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1549778 | Sertad1 | SERTA domain containing 1 | INVOLVED IN negative regulation of cell growth (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Colonic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS W ITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 91903297 | 91906565 | Rat | 176 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564049 | Sertad2 | SERTA domain containing 2 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN negative regulation of cell growth (ortholog); positive regulation of DNA-templated transcription (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,1,1-Tri chloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 98935428 | 99039536 | Rat | 117 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562244 | Sestd1 | SEC14 and spectrin domain containing 1 | ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog); phosphatidic acid binding (ortholog); phosphatidylcholine binding (ortholog); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); ASSOCIATED WITH Weight Ga in (ortholog); FOUND IN calcium channel complex (ortholog); intermediate filament cytoskeleton (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 82530796 | 82627960 | Rat | 109 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1308482 | Sfxn1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (ortholog); L-serine transmembrane transporter activity (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); L-alanine transport (ortholog); ASSOCIATED WITH Animal Disease Models (o rtholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 17 | 10491315 | 10527793 | Rat | 184 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303076 | Sh2d2a | SH2 domain containing 2A | INVOLVED IN cell population proliferation (ortholog); PARTICIPATES IN Erk5 MAPK signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH COVID-19 (ortholog); juvenile rheumatoid arthritis (ortholog); multiple sclerosis (ortholog); INTERACTS WITH 17beta-estradiol 3-ben zoate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 175610127 | 175616685 | Rat | 77 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308118 | Sh3bgrl3 | SH3 domain binding glutamate-rich protein like 3 | ENCODES a protein that exhibits glutathione transferase activity (ortholog); INVOLVED IN cytoskeleton organization (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol; ruffle membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-te trachlorodibenzodioxine | 5 | 151637897 | 151639270 | Rat | 137 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305609 | Shcbp1l | SHC binding and spindle associated 1 like | INVOLVED IN positive regulation of chromosome organization (ortholog); spermatogenesis (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN meiotic spindle (ortholog); INTERACTS WITH 3,7-dihydropurine-6-thione; bisphenol A; mercaptopurine | 13 | 68118861 | 68149646 | Rat | 35 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565710 | Shisa3 | shisa family member 3 | INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 14 | 40917563 | 40922135 | Rat | 77 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312041 | Shisa4 | shisa family member 4 | FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 13 | 49351518 | 49355599 | Rat | 62 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308004 | Shpk | sedoheptulokinase | ENCODES a protein that exhibits sedoheptulokinase activity (ortholog); INVOLVED IN carbohydrate metabolic process (ortholog); cellular response to interleukin-13 (ortholog); cellular response to interleukin-4 (ortholog); ASSOCIATED WITH SEDOHEPTULOKINASE DEFICIENCY (ortholog); FOUND IN cytoplasm (or tholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 10 | 58316065 | 58340489 | Rat | 101 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310610 | Shq1 | SHQ1, H/ACA ribonucleoprotein assembly factor | INVOLVED IN positive regulation of TORC1 signaling (ortholog); protein-RNA complex assembly (ortholog); regulation of androgen receptor signaling pathway (ortholog); ASSOCIATED WITH dystonia 35, childhood-onset (ortholog); NEURODEVELOPMENTAL DISORDER WITH DYSTONIA AND SEIZURES (ortholog); FOUND IN C ajal body (ortholog); cytoplasm (ortholog); nucleolus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 134741190 | 134861960 | Rat | 77 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308374 | Sirt3 | sirtuin 3 | ENCODES a protein that exhibits enzyme binding; histone H3K14 deacetylase activity, NAD-dependent (ortholog); NAD-dependent protein lysine deacetylase activity (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade; negative regulation of reactive oxygen species metabolic process; posi tive regulation of insulin secretion; PARTICIPATES IN histone modification pathway; Sirtuin mediated pathway; ASSOCIATED WITH congestive heart failure; metabolic dysfunction-associated steatotic liver disease; myocardial infarction; FOUND IN cytoplasm (ortholog); membrane (ortholog); mitochondrial inner membrane (ortholog); INTERACTS WITH (+)-schisandrin B; (R)-lipoic acid; 1,3,7,9-tetramethyluric acid | 1 | 205371703 | 205394145 | Rat | 339 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305216 | Sirt6 | sirtuin 6 | ENCODES a protein that exhibits protein lysine deacetylase activity; chromatin binding (ortholog); chromatin DNA binding (ortholog); INVOLVED IN cellular response to angiotensin; cellular response to endothelin; cellular response to hydrogen peroxide; PARTICIPATES IN histone modification pathway; Si rtuin mediated pathway; ASSOCIATED WITH Cardiomegaly; metabolic dysfunction-associated steatotic liver disease; obesity; FOUND IN chromatin (ortholog); chromosome, subtelomeric region (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 7 | 8733056 | 8738543 | Rat | 245 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311125 | Slc16a11 | solute carrier family 16, member 11 | ENCODES a protein that exhibits pyruvate transmembrane transporter activity (ortholog); INVOLVED IN lipid metabolic process (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 55427773 | 55431678 | Rat | 103 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1304605 | Slc22a22 | solute carrier family 22 member 22 | ENCODES a protein that exhibits prostaglandin receptor activity (ortholog); INVOLVED IN sodium-independent prostaglandin transport (ortholog); ASSOCIATED WITH glioblastoma (ortholog); hepatocellular carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN basolateral plasma membrane (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; allopurinol; bisphenol A | 7 | 90610007 | 90639718 | Rat | 49 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311498 | Slc25a17 | solute carrier family 25 member 17 | ENCODES a protein that exhibits ADP transmembrane transporter activity (ortholog); AMP transmembrane transporter activity (ortholog); ATP transmembrane transporter activity (ortholog); INVOLVED IN ATP transport (ortholog); fatty acid beta-oxidation (ortholog); fatty acid transport (ortholog); FOUND IN peroxisomal membrane (ortholog); peroxisome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; atrazine | 7 | 114724533 | 114767163 | Rat | 90 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359554 | Slc25a19 | solute carrier family 25 member 19 | ENCODES a protein that exhibits deoxynucleotide transmembrane transporter activity (ortholog); thiamine pyrophosphate transmembrane transporter activity (ortholog); INVOLVED IN deoxynucleotide transport (ortholog); thiamine diphosphate biosynthetic process (ortholog); thiamine pyrophosphate transmem brane transport (ortholog); ASSOCIATED WITH Amish Lethal Microcephaly (ortholog); genetic disease (ortholog); microcephaly (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 101353426 | 101366551 | Rat | 128 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311982 | Slc25a24 | solute carrier family 25 member 24 | ENCODES a protein that exhibits adenine nucleotide transmembrane transporter activity (ortholog); ADP:phosphate antiporter activity (ortholog); ATP transmembrane transporter activity (ortholog); INVOLVED IN adenine nucleotide transport (ortholog); cellular response to calcium ion (ortholog); cellula r response to oxidative stress (ortholog); ASSOCIATED WITH dementia (ortholog); Desbuquois dysplasia (ortholog); epilepsy with generalized tonic-clonic seizures (ortholog); FOUND IN membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4,4'-diaminodiphenylmethane | 2 | 199449425 | 199487287 | Rat | 145 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565789 | Slc25a32 | solute carrier family 25 member 32 | ENCODES a protein that exhibits FAD transmembrane transporter activity (ortholog); INVOLVED IN mitochondrial FAD transmembrane transport (ortholog); PARTICIPATES IN folate cycle metabolic pathway; ASSOCIATED WITH Exercise Intolerance (ortholog); prostate cancer (ortholog); FOUND IN mitochondrial inn er membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 7 | 72024535 | 72045692 | Rat | 102 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308898 | Slc26a8 | solute carrier family 26 member 8 | ENCODES a protein that exhibits chloride channel activity (ortholog); oxalate transmembrane transporter activity (ortholog); sulfate transmembrane transporter activity (ortholog); INVOLVED IN chloride transport (ortholog); oxalate transport (ortholog); sulfate transmembrane transport (ortholog); ASS OCIATED WITH schizophrenia (ortholog); spermatogenic failure 3 (ortholog); FOUND IN plasma membrane (ortholog); sperm annulus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 20 | 6687207 | 6751184 | Rat | 58 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309250 | Slc30a6 | solute carrier family 30 member 6 | ENCODES a protein that exhibits zinc ion transmembrane transporter activity (ortholog); zinc:proton antiporter activity (ortholog); INVOLVED IN Golgi to endosome transport (ortholog); regulation of zinc ion transport (ortholog); zinc ion import into Golgi lumen (ortholog); ASSOCIATED WITH Alzheimer' s disease (ortholog); FOUND IN Golgi apparatus; apical plasma membrane (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 6 | 26772804 | 26802656 | Rat | 105 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1565318 | Slc35b2 | solute carrier family 35 member B2 | ENCODES a protein that exhibits 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity (ortholog); INVOLVED IN 3'-phosphoadenosine 5'-phosphosulfate transport (ortholog); 5'-adenylyl sulfate transmembrane transport (ortholog); chondroitin sulfate proteoglycan biosynthetic process ( ortholog); ASSOCIATED WITH hypomyelinating leukodystrophy 26 (ortholog); spondyloepimetaphyseal dysplasia with joint laxity (ortholog); Treacher Collins syndrome 3 (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 9 | 22936031 | 22940114 | Rat | 105 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311250 | Slc35c2 | solute carrier family 35 member C2 | INVOLVED IN negative regulation of gene expression (ortholog); positive regulation of Notch signaling pathway (ortholog); protein O-linked glycosylation via fucose (ortholog); FOUND IN cis-Golgi network; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3,4,5,3',4',5'-Hexachlorobiphenyl | 3 | 174431688 | 174442852 | Rat | 69 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308229 | Slc43a1 | solute carrier family 43 member 1 | ENCODES a protein that exhibits L-amino acid transmembrane transporter activity (ortholog); L-isoleucine transmembrane transporter activity (ortholog); L-leucine transmembrane transporter activity (ortholog); INVOLVED IN isoleucine transport (ortholog); L-amino acid transport (ortholog); L-leucine t ransport (ortholog); FOUND IN apical plasma membrane (ortholog); plasma membrane (ortholog); podocyte foot (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 90327250 | 90353438 | Rat | 163 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311627 | Slc66a1 | solute carrier family 66 member 1 | ENCODES a protein that exhibits basic amino acid transmembrane transporter activity; L-arginine transmembrane transporter activity (ortholog); L-histidine transmembrane transporter activity (ortholog); INVOLVED IN intracellular amino acid homeostasis; L-arginine transmembrane transport (ortholog); L -histidine transmembrane transport (ortholog); ASSOCIATED WITH cystinosis (ortholog); FOUND IN lysosomal membrane; organelle membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; aflatoxin B1 | 5 | 156821084 | 156835558 | Rat | 112 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1309313 | Slc68a1 | solute carrier family 68 member 1 | FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; furan; paracetamol | 1 | 255158338 | 255177731 | Rat | 61 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1562492 | Slc6a21 | solute carrier family 6 member 21 | ENCODES a protein that exhibits metal ion binding (inferred); symporter activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN membrane (inferred); INTERACTS WITH C60 fullerene; cadmium dichloride; copper atom | 1 | 104890692 | 104902318 | Rat | 17 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1305905 | Slc7a4 | solute carrier family 7, member 4 | ENCODES a protein that exhibits amino acid transmembrane transporter activity (inferred); carboxylic acid transmembrane transporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN amino acid transmembrane transport (inferred); amino acid transport (inferred); carboxyl ic acid transmembrane transport (inferred); FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 11 | 96939456 | 96943127 | Rat | 63 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303102 | Slpi-ps1 | secretory leukocyte peptidase inhibitor, pseudogene 1 | ENCODES a pseudogene that exhibits peptidase inhibitor activity (inferred); INVOLVED IN defense response to bacterium (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil | 3 | 173438485 | 173440746 | Rat | 23 | UniProt | gene, pseudo, INFERRED [RefSeq] |
| 1311257 | Slx9 | SLX9 ribosome biogenesis factor | INVOLVED IN maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (inferred); FOUND IN nucleolus (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 20 | 11114214 | 11147112 | Rat | 45 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311869 | Smarcd3 | SWI/SNF related BAF chromatin remodeling complex subunit D3 | ENCODES a protein that exhibits chromatin binding; transcription factor binding; DNA-binding transcription factor binding (ortholog); INVOLVED IN positive regulation of G2/M transition of mitotic cell cycle; positive regulation of smooth muscle cell differentiation; cardiac right ventricle formation (ortholog); PARTICIPATES IN SWI/SNF family mediated chromatin remodeling pathway; ASSOCIATED WITH Left Ventricular Hypertrophy; COVID-19 (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nBAF complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrolein | 4 | 11441142 | 11472781 | Rat | 126 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306681 | Smoc2 | SPARC related modular calcium binding 2 | ENCODES a protein that exhibits calcium ion binding (ortholog); glycosaminoglycan binding (ortholog); heparin binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of angiogenesis (ortholog); positive regulation of cell-substrate adhesion (ortholog); ASSOC IATED WITH Dentin Dysplasia, Type 1 (ortholog); Desbuquois dysplasia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN basement membrane (ortholog); cell periphery (ortholog); extracellular matrix (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate | 1 | 63935627 | 64064952 | Rat | 208 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359716 | Smokl3 | sperm motility kinase like 3 | INTERACTS WITH glyphosate | 7 | 16444929 | 16460250 | Rat | 1 | old_protein_id | gene, pseudo, PREDICTED [RefSeq] |
| 1306049 | Smox | spermine oxidase | ENCODES a protein that exhibits polyamine oxidase activity; INVOLVED IN spermine catabolic process; polyamine catabolic process (ortholog); PARTICIPATES IN polyamine metabolic pathway; ASSOCIATED WITH middle cerebral artery infarction (ortholog); stroke (ortholog); FOUND IN cytoplasm (ortholog); cyt osol (ortholog); nuclear membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 139184793 | 139220174 | Rat | 199 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1549719 | Smpd1 | sphingomyelin phosphodiesterase 1 | ENCODES a protein that exhibits acid sphingomyelin phosphodiesterase activity (ortholog); phosphatidylcholine phospholipase C activity (ortholog); sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process; positive regulation of apoptotic process; response to coc aine; PARTICIPATES IN ceramide signaling pathway; FasL mediated signaling pathway; Trail mediated signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; Wilson disease; Gaucher's disease (ortholog); FOUND IN extracellular space; lamellar body; endolysosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 1 | 169304772 | 169308615 | Rat | 254 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564826 | Sms | spermine synthase | ENCODES a protein that exhibits spermine synthase activity; INVOLVED IN spermine biosynthetic process; spermine metabolic process (ortholog); PARTICIPATES IN spermine metabolic pathway; methionine cycle/metabolic pathway; polyamine metabolic pathway; ASSOCIATED WITH anxiety disorder (ortholog); Deve lopmental Disease (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol | X | 41331693 | 41387713 | Rat | 119 | old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304671 | Snapc1 | small nuclear RNA activating complex, polypeptide 1 | PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH amitrole; bisphenol A; diethylstilbestrol | 6 | 98420588 | 98442065 | Rat | 74 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307120 | Snrnp70 | small nuclear ribonucleoprotein U1 subunit 70 | ENCODES a protein that exhibits U1 snRNP binding; RNA binding (ortholog); U1 snRNA binding (ortholog); INVOLVED IN cellular response to retinoic acid; cellular response to transforming growth factor beta stimulus; cellular response to tumor necrosis factor; PARTICIPATES IN spliceosome pathway; ASSOC IATED WITH Alzheimer's disease (ortholog); Developmental Disabilities (ortholog); disease of mental health (ortholog); FOUND IN U1 snRNP; lysosomal lumen (ortholog); nuclear speck (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 1 | 104992518 | 105012851 | Rat | 148 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310194 | Snrpb2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding; INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog); FOUND IN small nuclear ribonucleoprotein complex; catalytic s tep 2 spliceosome (ortholog); nuclear speck (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; finasteride | 3 | 150852814 | 150862364 | Rat | 105 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306345 | Snrpd1 | small nuclear ribonucleoprotein D1 polypeptide | ENCODES a protein that exhibits U1 snRNP binding; INVOLVED IN mRNA splicing, via spliceosome (ortholog); spliceosomal snRNP assembly (ortholog); PARTICIPATES IN spliceosome pathway; systemic lupus erythematosus pathway; ASSOCIATED WITH nephritis; proteinuria; systemic lupus erythematosus; FOUND IN U 1 snRNP; catalytic step 2 spliceosome (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 1969351 | 1980207 | Rat | 167 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305782 | Snx10 | sorting nexin 10 | ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog); ATPase binding (ortholog); INVOLVED IN bone mineralization involved in bone maturation (ortholog); bone remodeling (ortholog); bone resorption (ortholog); ASSOCIATED WITH autosomal recessive osteopetrosis 8 (ortholog); COVID- 19 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN apical cytoplasm (ortholog); centrosome (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 4 | 81943262 | 82007667 | Rat | 184 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310291 | Snx2 | sorting nexin 2 | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); identical protein binding (ortholog); insulin receptor binding (ortholog); INVOLVED IN lamellipodium morphogenesis (ortholog); retrograde transport, endosome to Golgi (ortholog); PARTICIPATES IN retromer-mediated pa thway; ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog); endosome (ortholog); endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; flutamide | 18 | 48800594 | 48842158 | Rat | 127 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1304647 | Snx6 | sorting nexin 6 | ENCODES a protein that exhibits dynactin binding (ortholog); protein homodimerization activity (ortholog); type I transforming growth factor beta receptor binding (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus; cellular response to amyloid-beta (ortholog); intracellula r protein transport (ortholog); PARTICIPATES IN retromer-mediated pathway; FOUND IN endosome; cytoplasm (ortholog); early endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; gentamycin | 6 | 77966141 | 78009343 | Rat | 111 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305480 | Snx7 | sorting nexin 7 | ENCODES a protein that exhibits phosphatidylinositol binding (inferred); INVOLVED IN positive regulation of autophagosome assembly (ortholog); protein transport (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN early endosome (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene | 2 | 208528041 | 208612597 | Rat | 89 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311718 | Sox18 | SRY-box transcription factor 18 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN angiogenesis (ortholog); blood vessel development (ortholog); blood vessel endothelial cell m igration (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); basal cell carcinoma (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); transcription regulator complex (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 189163000 | 189164802 | Rat | 204 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359550 | Sp100 | SP100 nuclear antigen | ENCODES a protein that exhibits chromo shadow domain binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN DNA damage response, signal transduction by p53 class mediator (ortholog); maintenance of protein location (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); Mre11 complex (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acetamide; bisphenol A | 9 | 93758975 | 93825068 | Rat | 169 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1306355 | Sp140 | SP140 nuclear body protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH B-Cell Chronic Lymphocytic Leukemia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 4,4 '-diaminodiphenylmethane; acetamide | 9 | 93672536 | 93722596 | Rat | 45 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307079 | Spag8 | sperm associated antigen 8 | ENCODES a protein that exhibits microtubule binding (inferred); INVOLVED IN flagellated sperm motility (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Leber congenital amaurosis (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); axonemal microtubule (ortholog); cilium (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 62697451 | 62699664 | Rat | 51 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564523 | Spata25 | spermatogenesis associated 25 | INVOLVED IN spermatogenesis (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 3 | 173981863 | 173983818 | Rat | 30 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565316 | Spatc1 | spermatogenesis and centriole associated 1 | ENCODES a protein that exhibits gamma-tubulin binding (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; endosulfan | 7 | 109863794 | 109888145 | Rat | 28 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359579 | Spetex2f | Spetex-2F protein | INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; cadmium atom | 15 | 5457458 | 5460606 | Rat | 12 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359198 | Spetex2g | Spetex-2G protein | INTERACTS WITH Cuprizon; indole-3-methanol; ochratoxin A | 15 | 5929946 | 5933558 | Rat | 6 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307757 | Sphk2 | sphingosine kinase 2 | ENCODES a protein that exhibits histone binding (ortholog); sphingosine kinase activity (ortholog); sphingosine-1-phosphate receptor activity (ortholog); INVOLVED IN female pregnancy; blood vessel development (ortholog); brain development (ortholog); PARTICIPATES IN ceramide signaling pathway; Fabry disease pathway; Gaucher's disease pathway; ASSOCIATED WITH Memory Disorders (ortholog); middle cerebral artery infarction (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 105317332 | 105324985 | Rat | 207 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303138 | Spint1 | serine peptidase inhibitor, Kunitz type 1 | ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity; INVOLVED IN cellular response to BMP stimulus; negative regulation of neural precursor cell proliferation; positive regulation of glial cell differentiation; ASSOCIATED WITH liver cirrhosis; Alzheimer's disease (ortholog); biliary atresia (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 126685017 | 126697957 | Rat | 133 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1559964 | Spnl2 | sialophorin like 2 | ENCODES a protein that exhibits transmembrane signaling receptor activity (inferred); INVOLVED IN regulation of T cell activation (inferred); regulation of T cell migration (inferred) | 12 | 21239923 | 21244886 | Rat | 7 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311613 | Spop | speckle type BTB/POZ protein | ENCODES a protein that exhibits identical protein binding (ortholog); molecular function inhibitor activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN glucose homeostasis (ortholog); negative regulation of transcription by RNA polymerase I I (ortholog); obsolete negative regulation of DNA-binding transcription factor activity (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH colorectal cancer (ortholog); Ductal Carcinoma (ortholog); Endometrial Neoplasms (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); nuclear speck (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A | 10 | 80854890 | 80935781 | Rat | 106 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305847 | Spopl | speckle type BTB/POZ protein like | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN negative regulation of protein ubiquitination (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); INTERACTS WITH 17beta-estr adiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 26478535 | 26552344 | Rat | 67 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562307 | Spsb4 | splA/ryanodine receptor domain and SOCS box containing 4 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN positive regulation of protein polyubiquitination (ortholog); protein ubiquitination (ortholog); regulation of circadian rhythm (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog) ; FOUND IN cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 8 | 106416039 | 106489271 | Rat | 123 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305194 | Spta1 | spectrin, alpha, erythrocytic 1 | ENCODES a protein that exhibits actin binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); hemopoiesis (ortholog); lymphocyte homeostasis (ortholog); ASSOCIATED WITH anemia (ortholog); congenital hemolytic anemia (o rtholog); Elliptocytosis 2 (ortholog); FOUND IN axon; cytoplasmic side of plasma membrane; cortical cytoskeleton (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 13 | 88735833 | 88811697 | Rat | 136 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1308506 | Srp14 | signal recognition particle 14 | ENCODES a protein that exhibits 7S RNA binding (inferred); endoplasmic reticulum signal peptide binding (inferred); RNA binding (inferred); INVOLVED IN protein targeting to ER (ortholog); FOUND IN nucleus (ortholog); signal recognition particle, endoplasmic reticulum targeting (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A | 3 | 125896128 | 125899819 | Rat | 78 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308437 | Srp19 | signal recognition particle 19 | ENCODES a protein that exhibits 7S RNA binding (ortholog); ribosome binding (ortholog); RNA binding (ortholog); INVOLVED IN SRP-dependent cotranslational protein targeting to membrane (inferred); ASSOCIATED WITH Shwachman-Diamond syndrome (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog) ; signal recognition particle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 18 | 26205888 | 26212171 | Rat | 96 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305376 | Srp68 | signal recognition particle 68 | ENCODES a protein that exhibits 7S RNA binding (ortholog); protein domain specific binding (ortholog); ribosome binding (ortholog); INVOLVED IN response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); Craniofacial Abnormalities (ortholog); Severe Congenital Neutropen ia 10 (ortholog); FOUND IN cytosol (ortholog); signal recognition particle (ortholog); signal recognition particle, endoplasmic reticulum targeting (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 101980089 | 102006913 | Rat | 108 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564787 | Srp72 | signal recognition particle 72 | ENCODES a protein that exhibits 7S RNA binding (ortholog); ribosome binding (ortholog); signal recognition particle binding (ortholog); INVOLVED IN SRP-dependent cotranslational protein targeting to membrane (inferred); ASSOCIATED WITH Bone Marrow Failure Syndrome 1 (ortholog); Chemical and Drug Ind uced Liver Injury (ortholog); cholestasis (ortholog); FOUND IN endoplasmic reticulum (ortholog); signal recognition particle (ortholog); signal recognition particle, endoplasmic reticulum targeting (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; buspirone | 14 | 31522424 | 31549978 | Rat | 116 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305107 | Srpk2 | SRSF protein kinase 2 | ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); ATP binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN angiogenesis (ortholog); intracellular signal transduction (ortholog); negative regulation of viral genome replication (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); FOUND IN presynapse; chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 4 | 12356983 | 12548345 | Rat | 174 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311504 | Srpra | SRP receptor subunit alpha | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN intracellular protein transport (inferred); SRP-dependent cotranslational protein targeting to membrane (inferred); ASSOCIATED WITH Shwachman-Diamond syndrome (ortholog); FO UND IN membrane (ortholog); signal recognition particle receptor complex (ortholog); INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; bisphenol A | 8 | 41818199 | 41824292 | Rat | 117 | old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1311258 | Srrm1 | serine and arginine repetitive matrix 1 | INVOLVED IN mRNA processing (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; mRNA decay pathway; RNA transport pathway; ASSOCIATED WITH gestational diabetes (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); spliceosomal complex (ortholog ); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 5 | 152843167 | 152875554 | Rat | 109 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310259 | Ssna1 | SS nuclear autoantigen 1 | ENCODES a protein that exhibits identical protein binding (ortholog); microtubule binding (ortholog); INVOLVED IN axon arborization (ortholog); axon extension (ortholog); axonogenesis (ortholog); FOUND IN axon (ortholog); axoneme (ortholog); centriole (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodi benzodioxine; 2,4,6-trinitrotoluene; 4,4'-sulfonyldiphenol | 3 | 28483107 | 28484571 | Rat | 88 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1310961 | Ssr1 | signal sequence receptor subunit 1 | PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 3,3',5,5'-tetrabromobisphenol A | 17 | 27039203 | 27067352 | Rat | 121 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308365 | Ssr2 | signal sequence receptor subunit 2 | INVOLVED IN in utero embryonic development (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred); INTERACTS WITH 17bet a-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 176346117 | 176354868 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303279 | St3gal6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | ENCODES a protein that exhibits N-acetyllactosaminide alpha-2,3-sialyltransferase activity (ortholog); INVOLVED IN cellular response to interleukin-6 (ortholog); glycolipid biosynthetic process (ortholog); glycoprotein biosynthetic process (ortholog); PARTICIPATES IN lacto-series glycosphingolipid m etabolic pathway; FOUND IN Golgi membrane (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 55530120 | 55590950 | Rat | 129 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560747 | St6galnac2 | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | ENCODES a protein that exhibits alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity (ortholog); INVOLVED IN glycoprotein biosynthetic process (ortholog); protein O-linked glycosylation (ortholog); protein sialylation (ortholog); ASSOCIATED WITH alcohol use disorder; IgA glomerulonephr itis (ortholog); FOUND IN Golgi membrane (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 102409048 | 102427299 | Rat | 105 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311584 | Stap1 | signal transducing adaptor family member 1 | ENCODES a protein that exhibits macrophage colony-stimulating factor receptor binding (ortholog); phosphotyrosine residue binding (ortholog); protein kinase binding (ortholog); INVOLVED IN cell surface receptor protein tyrosine kinase signaling pathway (ortholog); cellular response to lipopolysaccha ride (ortholog); negative regulation of macrophage chemotaxis (ortholog); ASSOCIATED WITH familial hypercholesterolemia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 14 | 22301278 | 22336218 | Rat | 94 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306548 | Stard10 | StAR-related lipid transfer domain containing 10 | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN bile acid secretion (ortholog); positive regulation of peroxisome proliferator activated receptor signaling pathway (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (ortholog); intercellular canaliculus (ortholog); membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 165130408 | 165159134 | Rat | 125 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359639 | Stard6 | StAR-related lipid transfer domain containing 6 | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN lipid transport (inferred); INTERACTS WITH (+)-pilocarpine; 2,2',5,5'-tetrachlorobiphenyl; acetamide | 18 | 66365526 | 66393439 | Rat | 32 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311649 | Stat2 | signal transducer and activator of transcription 2 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN cell surface receptor signaling pathway via JAK-STAT (ortholog); defense response to virus (ortholog); negative regulation of type I interferon-mediated signaling pathway (ortholog); PARTICIPATES IN interleukin-27 signaling pathway; Jak-Stat signaling pathway; chemokine mediated signaling pathway; ASSOCIATED WITH Reperfusion Injury; Arenaviridae infectious disease (ortholog); Bunyaviridae Infections (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A | 7 | 1287025 | 1302858 | Rat | 249 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305747 | Stat4 | signal transducer and activator of transcription 4 | ENCODES a protein that exhibits sequence-specific DNA binding; DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to cytokine stimulus; cell population proliferation (ortholog); cytokine-mediated signaling pathwa y (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; ASSOCIATED WITH asthma; chronic obstructive pulmonary disease; Experimental Autoimmune Encephalomyelitis; FOUND IN cytoplasm (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 7,12-dimethyltetraphene; acetamide; aconitine | 9 | 56964617 | 57080523 | Rat | 253 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309063 | Stat6 | signal transducer and activator of transcription 6 | ENCODES a protein that exhibits DNA-binding transcription factor activity; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to hydrogen peroxide; cellular response to reactive nitrogen species; cytokine- mediated signaling pathway; PARTICIPATES IN interleukin-12 signaling pathway; interleukin-4 signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH asthma; myocarditis; renal fibrosis; FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 7 | 65365505 | 65382825 | Rat | 292 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305046 | Stk11ip | serine/threonine kinase 11 interacting protein | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN intracellular protein localization (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 9 | 84459733 | 84476521 | Rat | 53 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305109 | Stom | stomatin | ENCODES a protein that exhibits identical protein binding (ortholog); ion channel inhibitor activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN host-mediated activation of viral genome replication (ortholog); positive regulation of protein targeting to membrane (ortholog); positive regulation of viral process (ortholog); FOUND IN cytoplasm (ortholog); cytoskeleton (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 3 | 39042503 | 39064818 | Rat | 174 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305807 | Stra6l | STRA6-like | ENCODES a protein that exhibits retinol transmembrane transporter activity (inferred); signaling receptor activity (inferred); INVOLVED IN retinol transport (ortholog); vitamin A import into cell (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; endosul fan | 5 | 64902552 | 64944216 | Rat | 41 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559462 | Sufu | SUFU negative regulator of hedgehog signaling | ENCODES a protein that exhibits beta-catenin binding (ortholog); protein kinase binding (ortholog); protein sequestering activity (ortholog); INVOLVED IN positive regulation of cellular response to drug; spermatid development; aorta development (ortholog); PARTICIPATES IN Hedgehog signaling pathway; basal cell carcinoma pathway; ASSOCIATED WITH brain glioblastoma multiforme; medulloblastoma; pre-malignant neoplasm; FOUND IN cilium (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 255199108 | 255296983 | Rat | 156 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305078 | Sulf2 | sulfatase 2 | ENCODES a protein that exhibits arylsulfatase activity (ortholog); N-acetylglucosamine-6-sulfatase activity (ortholog); INVOLVED IN positive regulation of endothelin production; bone development (ortholog); cartilage development (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); endome triosis (ortholog); FOUND IN cell surface (ortholog); endoplasmic reticulum (ortholog); extracellular region (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1-nitropropane | 3 | 175241322 | 175323808 | Rat | 310 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359142 | Sun1 | Sad1 and UNC84 domain containing 1 | ENCODES a protein that exhibits cytoskeleton-nuclear membrane anchor activity (ortholog); identical protein binding (ortholog); lamin binding (ortholog); INVOLVED IN ossification; response to mechanical stimulus; centrosome localization (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); Eme ry-Dreifuss muscular dystrophy (ortholog); progeria (ortholog); FOUND IN acrosomal membrane (ortholog); chromosome, telomeric region (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 12 | 20510230 | 20555123 | Rat | 113 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306372 | Supt4h1 | SPT4 homolog, DSIF elongation factor subunit | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription, elongation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulati on of DNA-templated transcription, elongation (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; FOUND IN DSIF complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 10 | 73036560 | 73042821 | Rat | 65 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562206 | Supt7l | SPT7 like, STAGA complex subunit gamma | ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN maintenance of protein location in nucleus (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH FISCHER-ZIRNSAK PROGEROID SYNDROME (ortholog); FOUND IN nucleoplasm (o rtholog); nucleus (ortholog); SAGA complex (ortholog); INTERACTS WITH bisphenol A; finasteride; gentamycin | 6 | 30653928 | 30664066 | Rat | 42 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307382 | Surf6 | surfeit 6 | ENCODES a protein that exhibits DNA binding (ortholog); molecular condensate scaffold activity (ortholog); RNA binding (ortholog); INVOLVED IN ribosome biogenesis (ortholog); FOUND IN chromosome (ortholog); granular component (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenz odioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 3 | 30619525 | 30630388 | Rat | 82 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303113 | Syap1 | synapse associated protein 1 | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellular response to insulin-like growth factor stimulus (ortholog); FOUND IN axon (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | X | 35423947 | 35458472 | Rat | 115 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310488 | Syvn1 | synoviolin 1 | ENCODES a protein that exhibits DNA-binding transcription factor binding; ATPase binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN ERAD pathway (ortholog); immature B cell differentiation (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN Endoplasmic R eticulum-associated degradation pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH epilepsy (ortholog); FOUND IN Derlin-1 retrotranslocation complex (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum quality control compartment (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 4-phenylbutyric acid; bisphenol A | 1 | 212766736 | 212775426 | Rat | 174 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1561605 | Tada2b | transcriptional adaptor 2B | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN RNA polymerase II transcription initiation pathway; FOUND IN SAGA complex (ortholog); SAGA-type complex (ortholog); IN TERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; acetamiprid | 14 | 78503939 | 78523715 | Rat | 52 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305907 | Taf10 | TATA-box binding protein associated factor 10 | ENCODES a protein that exhibits DNA binding (ortholog); enzyme binding (ortholog); histone acetyltransferase activity (ortholog); INVOLVED IN allantois development (ortholog); apoptotic process (ortholog); DNA-templated transcription initiation (ortholog); PARTICIPATES IN RNA polymerase II transcrip tion initiation pathway; ASSOCIATED WITH dilated cardiomyopathy (ortholog); familial hypertrophic cardiomyopathy (ortholog); hypertrophic cardiomyopathy 1 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride | 1 | 169506940 | 169508234 | Rat | 143 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1305398 | Taf13 | TATA-box binding protein associated factor 13 | ENCODES a protein that exhibits DNA binding (ortholog); TBP-class protein binding (ortholog); INVOLVED IN mRNA transcription by RNA polymerase II (ortholog); positive regulation of transcription initiation by RNA polymerase II (ortholog); RNA polymerase II preinitiation complex assembly (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal recessive intellectual developmental disorder 60 (ortholog); genetic disease (ortholog); primary autosomal recessive microcephaly (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 2 | 198893332 | 198903994 | Rat | 104 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1310215 | Taf5l1 | TATA-box binding protein associated factor 5 like 1 | ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); regulation of somatic stem cell population maintenance (ortholog); regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymer ase II transcription initiation pathway; FOUND IN nuclear speck (ortholog); nucleus (ortholog); SAGA complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 19 | 68889153 | 68908480 | Rat | 80 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310123 | Taf6l | TATA-box binding protein associated factor 6 like | ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); regulation of somatic stem cell population maintenance (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); SAGA complex (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 215101266 | 215113888 | Rat | 69 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1308591 | Tasp1 | taspase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); threonine-type endopeptidase activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); proteolysis (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); genetic disease (ortholog) ; Multiple Abnormalities (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 3 | 147630092 | 147861710 | Rat | 68 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311641 | Tbc1d10a | TBC1 domain family, member 10a | ENCODES a protein that exhibits GTPase activator activity (ortholog); PDZ domain binding (ortholog); INVOLVED IN positive regulation of proteolysis (ortholog); regulation of cilium assembly (ortholog); retrograde transport, endosome to Golgi (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; paracetamol | 14 | 83278151 | 83307178 | Rat | 82 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311490 | Tbc1d10c | TBC1 domain family, member 10C | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN negative regulation of B cell activation (ortholog); negative regulation of calcineurin-NFAT signaling cascade (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); FOUND IN filopodium membrane (ortholog ); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | 1 | 210906621 | 210913649 | Rat | 73 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307920 | Tbc1d15 | TBC1 domain family, member 15 | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN regulation of cilium assembly (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular region (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine | 7 | 52690770 | 52746309 | Rat | 109 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309686 | Tbc1d17 | TBC1 domain family, member 17 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of cilium assembly (ortholog); retrograde transport, endosome to Golgi (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinit rotoluene | 1 | 104461266 | 104469615 | Rat | 82 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304958 | Tbc1d19 | TBC1 domain family, member 19 | INVOLVED IN regulation of cilium assembly (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acetamide | 14 | 61297193 | 61413106 | Rat | 53 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303293 | Tbc1d20 | TBC1 domain family, member 20 | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN acrosome assembly (ortholog); camera-type eye development (ortholog); COPII-coated vesicle cargo loading (ortholog); ASSOCIATED WITH genetic disease (ortholog); Warburg micro syndrome ( ortholog); Warburg micro syndrome 4 (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); Golgi membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 3 | 161228699 | 161247319 | Rat | 83 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559711 | Tbc1d25 | TBC1 domain family, member 25 | ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN regulation of autophagosome maturation (ortholog); ASSOCIATED WITH oligospermia (ortholog); FOUND IN autophagosome (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2-methoxyethanol; bisphenol A | X | 16986629 | 17010228 | Rat | 47 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311369 | Tcea3 | transcription elongation factor A3 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); nucleic acid binding (inferred); INVOLVED IN gene expression (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-est radiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 153760401 | 153792934 | Rat | 157 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311583 | Tead3 | TEA domain transcription factor 3 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN asymmetric neuroblast division (ortholog); hippo signaling (ortholog); positive regulation of stem cell population maintenance (ortholog); FOUND IN transcription regulator complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A | 20 | 6393786 | 6413177 | Rat | 90 | UniProt | gene, protein-coding, REVIEWED [RefSeq] |
| 1307081 | Tekt5 | tektin 5 | INVOLVED IN flagellated sperm motility; ASSOCIATED WITH schizophrenia (ortholog); FOUND IN axonemal A tubule inner sheath; sperm flagellum; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 10 | 5786656 | 5823411 | Rat | 53 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 1311574 | Terf1 | telomeric repeat binding factor 1 | ENCODES a protein that exhibits ankyrin repeat binding (ortholog); DNA binding, bending (ortholog); double-stranded telomeric DNA binding (ortholog); INVOLVED IN response to xenobiotic stimulus; meiotic telomere clustering (ortholog); negative regulation of DNA replication (ortholog); ASSOCIATED WIT H breast cancer (ortholog); squamous cell carcinoma (ortholog); stomach cancer (ortholog); FOUND IN chromosome, telomeric region (ortholog); nuclear body (ortholog); nuclear telomere cap complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 5 | 8226345 | 8255614 | Rat | 184 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303185 | Tfap2c | transcription factor AP-2 gamma | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cell differentiation (ortholog); cerebral cortex development (ortholog); dichotomous subdivis ion of terminal units involved in mammary gland duct morphogenesis (ortholog); ASSOCIATED WITH microcephaly (ortholog); Stomach Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 3 | 181733524 | 181742412 | Rat | 180 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305814 | Tfdp2 | transcription factor Dp-2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); protein domain specific binding (ortholog); INVOLVED IN heart development; negative regulation of DNA-templated transcription (or tholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; ASSOCIATED WITH COVID-19 (ortholog); malignant mesothelioma (ortholog); FOUND IN nucleoplasm (ortholog); RNA polymerase II transcription regulator complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; aflatoxin B1 | 8 | 105640018 | 105781026 | Rat | 155 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1309583 | Tfeb | transcription factor EB | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN antibacterial innate immune response (ortholog); cellular response to amino acid starvation ( ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH Nerve Degeneration (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 9 | 20696440 | 20752265 | Rat | 222 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308109 | Thap3 | THAP domain containing 3 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 5 | 167771209 | 167776878 | Rat | 60 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308657 | Thoc1 | THO complex subunit 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; RNA transport pathway; spliceosome pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 86 (ortholog); FOUND IN chromosome, te lomeric region (ortholog); cytoplasm (ortholog); nuclear speck (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 18 | 1253041 | 1291956 | Rat | 104 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311669 | Thoc3 | THO complex subunit 3 | INVOLVED IN mRNA export from nucleus (ortholog); PARTICIPATES IN RNA transport pathway; spliceosome pathway; FOUND IN chromosome, telomeric region (ortholog); nucleoplasm (ortholog); THO complex part of transcription export complex (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; amitrole; bispheno l A | 17 | 10148281 | 10157472 | Rat | 57 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308854 | Thumpd1 | THUMP domain 1 NAT10 acetyltransferase adaptor | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN tRNA modification (inferred); ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH SPEECH DELAY AND VARIABLE OCULAR ANOMALIES (ortholog); INTERACTS WITH (R,R,R)-alpha-tocopherol; 1,2-dimethylhydrazine; 2,4-dinitrotoluene | 1 | 183510242 | 183516282 | Rat | 73 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305742 | Tia1 | TIA1 cytotoxic granule-associated RNA binding protein | ENCODES a protein that exhibits mRNA 3'-UTR AU-rich region binding (ortholog); mRNA 3'-UTR binding (ortholog); RNA binding (ortholog); INVOLVED IN positive regulation of epithelial cell apoptotic process; negative regulation of cytokine production (ortholog); negative regulation of translation (orth olog); ASSOCIATED WITH transient cerebral ischemia; amyotrophic lateral sclerosis type 26 (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic stress granule; ribonucleoprotein complex; cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 4 | 120410180 | 120440676 | Rat | 217 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359192 | Tinf2 | TERF1 interacting nuclear factor 2 | ENCODES a protein that exhibits DNA binding (ortholog); telomeric DNA binding (ortholog); INVOLVED IN negative regulation of epithelial cell proliferation (ortholog); negative regulation of telomere maintenance (ortholog); negative regulation of telomere maintenance via telomerase (ortholog); ASSOCI ATED WITH aplastic anemia (ortholog); Autosomal Dominant Dyskeratosis Congenita (ortholog); autosomal dominant dyskeratosis congenita 1 (ortholog); FOUND IN chromosome, telomeric region (ortholog); nuclear body (ortholog); nuclear telomere cap complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 15 | 33140611 | 33146930 | Rat | 115 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308215 | Tlcd3b | TLC domain containing 3B | ENCODES a protein that exhibits sphingosine N-acyltransferase activity (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); negative regulation of fat cell differentiation (ortholog); ASSOCIATED WITH cone-rod dystrophy 22 (ortholog); spondylocostal dysostosis 5 (ortholog); FOUND IN endo plasmic reticulum (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole | 1 | 190851582 | 190870278 | Rat | 61 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311666 | Tlnrd1 | talin rod domain containing 1 | ENCODES a protein that exhibits actin binding (ortholog); identical protein binding (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN stress fiber (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 1 | 147273475 | 147275494 | Rat | 83 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564460 | Tlr11 | toll-like receptor 11 | INVOLVED IN response to bacterium (ortholog); PARTICIPATES IN toxoplasmosis pathway; ASSOCIATED WITH membranoproliferative glomerulonephritis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH bisphenol A; 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog); 2,2',4,4',5,5'-hexachlorobiphe nyl (ortholog) | 15 | 26018987 | 26023426 | Rat | 23 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1563357 | Tlr7 | toll-like receptor 7 | ENCODES a protein that exhibits double-stranded RNA binding (ortholog); pattern recognition receptor activity (ortholog); single-stranded RNA binding (ortholog); INVOLVED IN canonical NF-kappaB signal transduction (ortholog); cellular response to mechanical stimulus (ortholog); cellular response to virus (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; influenza A pathway; measles pathway; ASSOCIATED WITH perinatal necrotizing enterocolitis; alcohol use disorder (ortholog); allergic contact dermatitis (ortholog); FOUND IN cytoplasm (ortholog); early phagosome (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | X | 30644324 | 30670796 | Rat | 202 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311205 | Tm7sf2 | transmembrane 7 superfamily member 2 | ENCODES a protein that exhibits Delta14-sterol reductase activity (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol biosynthetic process via lathosterol (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol este r storage disease pathway; FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); organelle membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 212785217 | 212789572 | Rat | 232 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359409 | Tmbim1 | transmembrane BAX inhibitor motif containing 1 | ENCODES a protein that exhibits death receptor binding (ortholog); INVOLVED IN negative regulation of catalytic activity (ortholog); negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of Fas signaling pathway (ortholog); ASSOCIATED WITH cerebrotendinous xanthomatosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN endosome membrane (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 83320972 | 83338469 | Rat | 122 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310481 | Tmem128 | transmembrane protein 128 | INTERACTS WITH alpha-Zearalanol; bisphenol A; methoxychlor | 14 | 76751848 | 76761576 | Rat | 42 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307703 | Tmem161a | transmembrane protein 161A | INVOLVED IN cellular response to oxidative stress (ortholog); cellular response to UV (ortholog); negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 16 | 19272433 | 19282173 | Rat | 63 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304793 | Tmem222 | transmembrane protein 222 | ASSOCIATED WITH genetic disease (ortholog); NEURODEVELOPMENTAL DISORDER WITH MOTOR AND SPEECH DELAY AND BEHAVIORAL ABNORMALITIES (ortholog); FOUND IN dendrite (ortholog); INTERACTS WITH 17beta-estradiol; acrylamide; bisphenol A | 5 | 150749746 | 150763031 | Rat | 48 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307922 | Tmem9 | transmembrane protein 9 | INVOLVED IN endosomal lumen acidification (ortholog); lysosomal lumen acidification (ortholog); positive regulation of canonical Wnt signaling pathway (ortholog); FOUND IN late endosome (ortholog); lysosomal membrane (ortholog); lysosome (ortholog); INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrac hlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 50008829 | 50027556 | Rat | 96 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1311030 | Tmod3 | tropomodulin 3 | ENCODES a protein that exhibits tropomyosin binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); erythrocyte development (ortholog); positive regulation of mitotic cell cycle phase transition (ortholog); FOUND IN striated muscle thin filament (ortholog); INTERACTS WITH (+)-sch isandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 8 | 85131295 | 85191477 | Rat | 80 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302967 | Tmprss11c | transmembrane protease, serine 11C | ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); self proteolysis (ortholog); FOUND IN dendrite (ortholog); perikaryon (ortholog); plasma membrane (ortholog); INTERACTS WITH cadmium dichloride; furan; Butylbenzyl phthalate (ortholog) | 14 | 22136865 | 22195312 | Rat | 29 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310872 | Tmprss13 | transmembrane serine protease 13 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN establishment of skin barrier (ortholog); PARTICIPATES IN influenza A pathway; FOUND IN membrane (inferred); INTERACTS WITH bisphenol A; bromobenze ne; endosulfan | 8 | 54522069 | 54550673 | Rat | 54 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310115 | Tnfrsf14 | TNF receptor superfamily member 14 | ENCODES a protein that exhibits cytokine binding (ortholog); receptor ligand activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); negative regulation of adaptive i mmune memory response (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH myocardial infarction; arteriosclerosis (ortholog); Brain Injuries (ortholog); FOUND IN external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether | 5 | 170768413 | 170776749 | Rat | 115 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1565872 | Tnfrsf18 | TNF receptor superfamily member 18 | ENCODES a protein that exhibits tumor necrosis factor receptor activity (inferred); INVOLVED IN positive regulation of cell adhesion (ortholog); positive regulation of leukocyte migration (ortholog); positive regulation of tyrosine phosphorylation of STAT protein (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH anogenital venereal wart (ortholog); HTLV-1-associated myelopathy/tropical spastic paraparesis (ortholog); leishmaniasis (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 171901734 | 171904578 | Rat | 83 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310917 | Tns2 | tensin 2 | ENCODES a protein that exhibits identical protein binding (ortholog); kinase binding (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN cellular homeostasis (ortholog); collagen metabolic process (ortholog); kidney development (ortholog); ASSOCIATED WITH nephrotic syndrome (or tholog); Pierson syndrome (ortholog); FOUND IN focal adhesion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 7 | 135108401 | 135126505 | Rat | 132 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308024 | Tom1 | target of myb1 membrane trafficking protein | ENCODES a protein that exhibits clathrin binding (ortholog); clathrin heavy chain binding (ortholog); myosin VI binding (ortholog); INVOLVED IN autophagosome-lysosome fusion (ortholog); endosomal transport (ortholog); positive regulation of autophagosome maturation (ortholog); ASSOCIATED WITH immuno deficiency 85 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); early endosome (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 19 | 13411227 | 13446129 | Rat | 121 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308431 | Tor1b | torsin family 1, member B | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); INVOLVED IN endoplasmic reticulum organization (ortholog); nuclear membrane organization (ortholog); ASSOCIATED WITH Human Influenza (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticu lum (ortholog); endoplasmic reticulum lumen (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 34640929 | 34647023 | Rat | 114 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562563 | Tra2a | transformer 2 alpha | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); positive regulation of mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Arsenic Poisoning (ortholog); skin disease (ortholog); F OUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 4 | 79551699 | 79570621 | Rat | 138 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1304848 | Traf3ip3 | TRAF3 interacting protein 3 | ENCODES a protein that exhibits molecular adaptor activity (ortholog); protein-macromolecule adaptor activity (ortholog); zf-TRAF domain binding (ortholog); INVOLVED IN antiviral innate immune response (ortholog); cellular response to interferon-alpha (ortholog); cellular response to interferon-beta (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); Golgi membrane (ortholog); mitochondrial membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 107223499 | 107248358 | Rat | 99 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306708 | Traf4 | Tnf receptor associated factor 4 | ENCODES a protein that exhibits identical protein binding (ortholog); protein kinase binding (ortholog); thioesterase binding (ortholog); INVOLVED IN positive regulation of JNK cascade (ortholog); positive regulation of protein kinase activity (ortholog); respiratory gaseous exchange by respiratory system (ortholog); PARTICIPATES IN small cell lung carcinoma pathway; ASSOCIATED WITH Brain Injuries (ortholog); lung adenocarcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); fibrillar center (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 63552251 | 63558356 | Rat | 166 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309761 | Traip | TRAF-interacting protein | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of interferon-beta production (ortholog); negative regulation of tumo r necrosis factor-mediated signaling pathway (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 1H-pyrazole | 8 | 117520476 | 117540253 | Rat | 147 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563011 | Trat1 | T cell receptor associated transmembrane adaptor 1 | INVOLVED IN negative regulation of receptor recycling (ortholog); negative regulation of transport (ortholog); positive regulation of calcium-mediated signaling (ortholog); FOUND IN centriolar satellite (ortholog); plasma membrane (ortholog); T cell receptor complex (ortholog); INTERACTS WITH alpha- Zearalanol; atrazine; bisphenol A | 11 | 65498742 | 65540823 | Rat | 43 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311998 | Trex1 | three prime repair exonuclease 1 | ENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog); 3'-5'-DNA exonuclease activity (ortholog); adenyl deoxyribonucleotide binding (ortholog); INVOLVED IN activation of immune response (ortholog); adaptive immune response (ortholog); apoptotic cell clearance (ortholog); PARTICIPATE S IN DNA replication pathway; G2/M DNA damage checkpoint pathway; ASSOCIATED WITH Aicardi-Goutieres syndrome (ortholog); Aicardi-Goutieres Syndrome 1 (ortholog); brain disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH (+)-pilocarpine; 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 118585082 | 118586382 | Rat | 238 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560596 | Trim24 | tripartite motif-containing 24 | ENCODES a protein that exhibits chromatin binding (ortholog); estrogen response element binding (ortholog); histone H3K23ac reader activity (ortholog); INVOLVED IN response to peptide hormone; calcium ion homeostasis (ortholog); cellular response to estrogen stimulus (ortholog); PARTICIPATES IN hist one modification pathway; retinoic acid signaling pathway; ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog); euchromatin (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 4 | 67534240 | 67659014 | Rat | 221 | old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1305238 | Trim32 | tripartite motif-containing 32 | ENCODES a protein that exhibits identical protein binding (ortholog); myosin binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN actin ubiquitination (ortholog); autophagosome assembly (ortholog); axon development (ortholog); PARTICIPATES IN ubiquitin/proteasome degrad ation pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2H (ortholog); Bardet-Biedl syndrome (ortholog); Bardet-Biedl syndrome 11 (ortholog); FOUND IN autophagosome (ortholog); centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine | 5 | 84020604 | 84031483 | Rat | 174 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304579 | Trim5 | tripartite motif-containing 5 | ENCODES a protein that exhibits identical protein binding (ortholog); pattern recognition receptor activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN activation of innate immune response (ortholog); autophagy (ortholog); host-mediated suppression of symbiont invasion (ort holog); ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); prostate cancer (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); omegasome (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 1 | 168132277 | 168149263 | Rat | 108 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311956 | Trim59 | tripartite motif-containing 59 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN host-mediated suppression of symbiont invasion (ortholog); innate immune response (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH Experimental Liver Cirrho sis (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 1-benzylpiperazine; 1-naphthyl isothiocyanate; 17beta-estradiol | 2 | 155579183 | 155593450 | Rat | 130 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306838 | Trip4 | thyroid hormone receptor interactor 4 | ENCODES a protein that exhibits histone acetyltransferase binding (ortholog); nuclear estrogen receptor binding (ortholog); nuclear receptor binding (ortholog); INVOLVED IN estrogen receptor signaling pathway (ortholog); positive regulation of DNA-templated transcription (ortholog); regulation of DN A-templated transcription (ortholog); ASSOCIATED WITH centronuclear myopathy (ortholog); Congenital Muscular Dystrophy, Davignon-Chauveau Type (ortholog); genetic disease (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); neuromuscular junction (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; Bergenin | 8 | 75248352 | 75334802 | Rat | 95 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310418 | Trmt2a | tRNA methyltransferase 2A | ENCODES a protein that exhibits C-methyltransferase activity (ortholog); tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent (ortholog); INVOLVED IN methylation (inferred); mRNA processing (inferred); RNA processing (inferred); FOUND IN cytosol (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 11 | 96241998 | 96246719 | Rat | 65 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308857 | Trnt1 | tRNA nucleotidyl transferase 1 | ENCODES a protein that exhibits CCA tRNA nucleotidyltransferase activity (ortholog); CCACCA tRNA nucleotidyltransferase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial tRNA 3'-end processing (ortholog); rescue of stalled cytosolic ribosome (ortholog); tRN A 3'-terminal CCA addition (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH fundus dystrophy (ortholog); genetic disease (ortholog); optic atrophy (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 4 | 141236937 | 141259700 | Rat | 93 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1309914 | Trpc4ap | transient receptor potential cation channel, subfamily C, member 4 associated protein | ENCODES a protein that exhibits phosphatase binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN hair follicle maturation (ortholog); protein ubiquitination (ortholog); ubiquitin-dependent protein catabolic process (ortholog); FOUND IN Cul4-RING E3 ubiquitin l igase complex (ortholog); Cul4A-RING E3 ubiquitin ligase complex (ortholog); cytosol (ortholog); INTERACTS WITH bisphenol A; C60 fullerene; cocaine | 3 | 164582146 | 164653123 | Rat | 74 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359444 | Tspan3 | tetraspanin 3 | ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 65442100 | 65465961 | Rat | 86 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308721 | Tspan32 | tetraspanin 32 | INVOLVED IN blood coagulation (ortholog); cytoskeleton organization (ortholog); defense response to protozoan (ortholog); FOUND IN cell surface (ortholog); integrin alphaIIb-beta3 complex (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 207619566 | 207633885 | Rat | 64 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560160 | Tspan6 | tetraspanin 6 | INVOLVED IN negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulation of cytoplasmic pattern recognition receptor signaling pathway (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); FOUND IN membrane (inferred); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | X | 101385686 | 101395371 | Rat | 84 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310192 | Tspy26 | testis specific protein, Y-linked 26 | INVOLVED IN nucleosome assembly (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 3 | 162150885 | 162152961 | Rat | 35 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306653 | Tspyl4 | TSPY-like 4 | INVOLVED IN nucleosome assembly (inferred); ASSOCIATED WITH melanoma (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl | 20 | 39653788 | 39655784 | Rat | 78 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304951 | Tssk2 | testis-specific serine kinase 2 | ENCODES a protein that exhibits magnesium ion binding (ortholog); protein serine/threonine kinase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein autophosphorylation (ortholog); spermatid development (ortholog); FOUN D IN acrosomal vesicle (ortholog); centriole (ortholog); cytoplasm (ortholog); INTERACTS WITH bisphenol A; cocaine; fluoxetine | 11 | 96590864 | 96592219 | Rat | 33 | old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359231 | Tssk3 | testis-specific serine kinase 3 | ENCODES a protein that exhibits magnesium ion binding (ortholog); manganese ion binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN spermatid development (ortholog); spermatogenesis (ortholog); FOUND IN sperm flagellum (ortholog); INTERACTS WITH 1,2-dimethylhydrazine ; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 147111944 | 147113593 | Rat | 47 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359604 | Ttc1 | tetratricopeptide repeat domain 1 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN positive regulation of neuroinflammatory response (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 28703763 | 28728910 | Rat | 65 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303264 | Ttc12 | tetratricopeptide repeat domain 12 | INVOLVED IN axonemal dynein complex assembly (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); alcohol dependence (ortholog); Asthenozoospermia (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodi benzodioxine; 6-propyl-2-thiouracil; acetamide | 8 | 58696381 | 58743857 | Rat | 101 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311126 | Ttc39a | tetratricopeptide repeat domain 39A | ASSOCIATED WITH Liver Neoplasms (ortholog); Wolff-Parkinson-White syndrome (ortholog); FOUND IN centrosome (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; acrylamide | 5 | 129379560 | 129441779 | Rat | 101 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306211 | Ttc7a | tetratricopeptide repeat domain 7A | INVOLVED IN protein localization to plasma membrane (ortholog); ASSOCIATED WITH common variable immunodeficiency (ortholog); Gastrointestinal defects and immunodeficiency syndrome (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7, 8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 6 | 12912822 | 13015374 | Rat | 94 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305887 | Tubb6 | tubulin, beta 6 class V | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); metal ion binding (inferred); INVOLVED IN cytoskeleton organization (inferred); microtubule-based process (inferred); PARTICIPATES IN phagocytosis pathway; ASSOCIATED WITH Congenital Facial Palsy with Ptosis and Velo pharyngeal Dysfunction (ortholog); Experimental Liver Cirrhosis (ortholog); ptosis (ortholog); FOUND IN microtubule (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate | 18 | 63213287 | 63222926 | Rat | 227 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309597 | Tubgcp2 | tubulin gamma complex component 2 | ENCODES a protein that exhibits gamma-tubulin binding (inferred); INVOLVED IN brain development (ortholog); neuron migration (ortholog); ASSOCIATED WITH pachygyria, microcephaly, developmental delay, and dysmorphic facies, with or without seizures (ortholog); FOUND IN centrosome (ortholog); microtub ule organizing center (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 1 | 204220725 | 204247460 | Rat | 69 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310551 | Tulp2 | TUB like protein 2 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); INTERACTS WITH 2-methoxyethanol; bisphenol A; decabromodiphenyl ether | 1 | 105098884 | 105136243 | Rat | 43 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303318 | Tusc3 | tumor suppressor candidate 3 | ENCODES a protein that exhibits oligosaccharyltransferase complex binding (ortholog); INVOLVED IN cognition (ortholog); magnesium ion transport (ortholog); protein N-linked glycosylation (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pa thway; ASSOCIATED WITH autosomal recessive intellectual developmental disorder 24 (ortholog); autosomal recessive intellectual developmental disorder 7 (ortholog); congenital disorder of glycosylation (ortholog); FOUND IN mitochondrion (ortholog); oligosaccharyltransferase complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 16 | 59899642 | 60048813 | Rat | 121 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306481 | Txk | TXK tyrosine kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); non-membrane spanning protein tyrosine kinase activity (inferred); INVOLVED IN adaptive immune response (ortholog); NK T cell differentiation (ortholog); positive regulation of cytokine production (ortholog); FOUND I N cytoplasm (ortholog); cytosol (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol | 14 | 35817270 | 35873454 | Rat | 99 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305127 | Txnl4b | thioredoxin-like 4B | INVOLVED IN mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); RNA splicing (inferred); FOUND IN nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 19 | 54439686 | 54449777 | Rat | 85 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307354 | Tysnd1 | trypsin like peroxisomal matrix peptidase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); protease binding (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN protein processing (ortholog); proteolysis (ortholog); regulation of fatty acid beta-oxidation (ortholog); FOUND IN peroxisome (ortholog); INT ERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 20 | 30180878 | 30188239 | Rat | 119 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310420 | Tyw1 | tRNA-yW synthesizing protein 1 homolog | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); catalytic activity (inferred); FMN binding (inferred); INVOLVED IN tRNA processing (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 12 | 31968198 | 32054454 | Rat | 68 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311689 | Ubac2 | UBA domain containing 2 | INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); negative regulation of retrograde protein transport, ER to cytosol (ortholog); protein localization to endoplasmic reticulum (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN endoplasmic reticulum (ort holog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene | 15 | 105366776 | 105514435 | Rat | 55 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359534 | Ube2a | ubiquitin-conjugating enzyme E2A | ENCODES a protein that exhibits ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN blastocyst hatching (ortholog); chromatin remodeling (ortholog); DNA repair (ortholog); PARTICIPATES IN ubiqui tin/proteasome degradation pathway; ASSOCIATED WITH genetic disease (ortholog); syndromic X-linked intellectual disability Nascimento type (ortholog); FOUND IN chromatin (ortholog); HULC complex (ortholog); XY body (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | X | 120979993 | 120990773 | Rat | 122 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1308894 | Ube2e3 | ubiquitin-conjugating enzyme E2E 3 | ENCODES a protein that exhibits ubiquitin conjugating enzyme activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN protein K11-linked ubiquitination (ortholog); protein K48-linked ubiquitination (ortholog); protein K63-linked ubiquitination (ortholog); PARTICIPATES IN E ndoplasmic Reticulum-associated degradation pathway; ubiquitin/proteasome degradation pathway; FOUND IN nucleus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil | 3 | 84194246 | 84250232 | Rat | 71 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305305 | Ube2q1 | ubiquitin conjugating enzyme E2 Q1 | ENCODES a protein that exhibits ubiquitin conjugating enzyme activity (ortholog); INVOLVED IN embryo implantation (ortholog); fertilization (ortholog); mating behavior (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; FOUND IN cytoplasm (inferred); INTERACTS WITH bisphenol A; och ratoxin A; paracetamol | 2 | 177496480 | 177505631 | Rat | 64 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303055 | Ubl7 | ubiquitin-like 7 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitroto luene | 8 | 67217151 | 67236224 | Rat | 64 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1305440 | Ubox5 | U-box domain containing 5 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-ubiquitin ligase activity (ortholog); INVOLVED IN protein polyubiquitination (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; FOUND IN nuclear bod y (ortholog); nucleus (ortholog); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride | 3 | 138259311 | 138300807 | Rat | 59 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304920 | Ubqln3 | ubiquilin 3 | PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH bisphenol A; fenvalerate; benzo[a]pyrene (ortholog) | 1 | 168016508 | 168019201 | Rat | 14 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359144 | Ubr7 | ubiquitin protein ligase E3 component n-recognin 7 | ENCODES a protein that exhibits metal ion binding (inferred); transferase activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN protein ubiquitination (inferred); ASSOCIATED WITH Developmental Disabilities (ortholog); intellectual disability (ortholog); Li-Campeau Syndrome ( ortholog); INTERACTS WITH bisphenol A; cyclophosphamide; dibutyl phthalate | 6 | 127663454 | 127683302 | Rat | 69 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308313 | Uck1 | uridine-cytidine kinase 1 | ENCODES a protein that exhibits cytidine kinase activity (ortholog); uridine kinase activity (ortholog); INVOLVED IN CTP salvage (ortholog); UMP salvage (ortholog); PARTICIPATES IN pyrimidine metabolic pathway; ASSOCIATED WITH nerve compression syndrome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodiox ine; 2,4-dinitrotoluene; bisphenol A | 3 | 35936328 | 35942213 | Rat | 83 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1562213 | Ucn3 | urocortin 3 | ENCODES a protein that exhibits corticotropin-releasing hormone receptor binding (ortholog); INVOLVED IN cellular response to hypoxia; cellular response to nutrient levels; positive regulation of insulin secretion; PARTICIPATES IN corticotropin-releasing hormone signaling pathway; ASSOCIATED WITH In flammation (ortholog); lung disease (ortholog); FOUND IN axon; axon terminus; varicosity; INTERACTS WITH acrylamide; bisphenol A; vinclozolin | 17 | 71219611 | 71225904 | Rat | 52 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1549741 | Ugt1a2 | UDP glucuronosyltransferase 1 family, polypeptide A2 | ENCODES a protein that exhibits enzyme binding (ortholog); glucuronosyltransferase activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN animal organ regeneration; liver development; bile acid secretion (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics path way; codeine and morphine pharmacokinetics pathway; ibuprofen pharmacodynamics pathway; ASSOCIATED WITH Crigler-Najjar syndrome (ortholog); Gilbert syndrome (ortholog); schizophrenia (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene | 9 | 96239019 | 96256264 | Rat | 302 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1549728 | Ugt1a3 | UDP glycosyltransferase 1 family, polypeptide A3 | ENCODES a protein that exhibits glucuronosyltransferase activity (ortholog); INVOLVED IN animal organ regeneration; bile acid secretion (ortholog); estrogen metabolic process (ortholog); PARTICIPATES IN ascorbate and aldarate metabolic pathway; O-linked glycan biosynthetic pathway; pentose and glucu ronate interconversion pathway; ASSOCIATED WITH Crigler-Najjar syndrome (ortholog); Gilbert syndrome (ortholog); Leber congenital amaurosis (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 96228134 | 96256264 | Rat | 79 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1549771 | Ugt1a9 | UDP glucuronosyltransferase family 1 member A9 | ENCODES a protein that exhibits enzyme binding (ortholog); enzyme inhibitor activity (ortholog); glucuronosyltransferase activity (ortholog); INVOLVED IN flavone metabolic process (ortholog); flavonoid metabolic process (ortholog); negative regulation of fatty acid metabolic process (ortholog); PART ICIPATES IN artemether pharmacokinetics pathway; ibuprofen pharmacodynamics pathway; ibuprofen pharmacokinetics pathway; ASSOCIATED WITH acute kidney failure (ortholog); Chemical and Drug Induced Liver Injury (ortholog); cholangiocarcinoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; amphotericin B | 9 | 96144786 | 96256264 | Rat | 316 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311908 | Umps | uridine monophosphate synthetase | ENCODES a protein that exhibits orotate phosphoribosyltransferase activity; orotidine-5'-phosphate decarboxylase activity; identical protein binding (ortholog); INVOLVED IN cellular response to xenobiotic stimulus; female pregnancy; lactation; PARTICIPATES IN beta-ureidopropionase deficiency pathway ; de novo pyrimidine biosynthetic pathway; dihydropyrimidinase deficiency pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; beta thalassemia (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 11 | 80311269 | 80321678 | Rat | 192 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307200 | Ung | uracil-DNA glycosylase | ENCODES a protein that exhibits uracil DNA N-glycosylase activity; damaged DNA binding (ortholog); ribosomal small subunit binding (ortholog); INVOLVED IN base-excision repair; negative regulation of apoptotic process; base-excision repair, AP site formation via deaminated base removal (ortholog); P ARTICIPATES IN base excision repair pathway; primary immunodeficiency pathway; ASSOCIATED WITH Bloom syndrome (ortholog); Colorectal Neoplasms (ortholog); dysgammaglobulinemia (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide | 12 | 48145838 | 48154789 | Rat | 263 | UniProt , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308778 | Upf3a | UPF3A, regulator of nonsense mediated mRNA decay | ENCODES a protein that exhibits mRNA binding (ortholog); protein sequestering activity (ortholog); telomeric DNA binding (ortholog); INVOLVED IN negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (ortholog); nuclear-transcribed mRNA catabolic process, nonsense -mediated decay (ortholog); positive regulation of mRNA cis splicing, via spliceosome (ortholog); PARTICIPATES IN mRNA decay pathway; RNA transport pathway; FOUND IN exon-exon junction complex (ortholog); neuron projection (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 16 | 82459651 | 82470686 | Rat | 93 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305566 | Upp1 | uridine phosphorylase 1 | ENCODES a protein that exhibits deoxyuridine phosphorylase activity (ortholog); identical protein binding (ortholog); thymidine phosphorylase activity (ortholog); INVOLVED IN cellular response to glucose starvation; CMP catabolic process (ortholog); dCMP catabolic process (ortholog); PARTICIPATES IN pyrimidine metabolic pathway; ASSOCIATED WITH middle cerebral artery infarction; allergic contact dermatitis (ortholog); long QT syndrome (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 14 | 88023155 | 88043036 | Rat | 251 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311971 | Uqcrb | ubiquinol-cytochrome c reductase binding protein | ENCODES a protein that exhibits protein-containing complex binding; INVOLVED IN mitochondrial electron transport, ubiquinol to cytochrome c (inferred); respiratory electron transport chain (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylatio n pathway; ASSOCIATED WITH depressive disorder; inherited metabolic disorder (ortholog); mitochondrial complex III deficiency nuclear type 1 (ortholog); FOUND IN respiratory chain complex III; mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 7 | 65700016 | 65705382 | Rat | 121 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1310396 | Uros | uroporphyrinogen III synthase | ENCODES a protein that exhibits folic acid binding; uroporphyrinogen-III synthase activity; INVOLVED IN cellular response to amine stimulus; cellular response to arsenic-containing substance; response to platinum ion; PARTICIPATES IN acute intermittent porphyria pathway; erythropoietic porphyria pat hway; heme biosynthetic pathway; ASSOCIATED WITH cutaneous porphyria; genetic disease (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 1 | 197920827 | 197943183 | Rat | 115 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303329 | Ush1c | USH1 protein network component harmonin | ENCODES a protein that exhibits myosin tail binding; spectrin binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); brush border assembly (ortholog); equilibrioception (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; retinitis pigmentosa pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); Autosomal Recessive Nonsyndromic Deafness 18 (ortholog); autosomal recessive nonsyndromic deafness 18A (ortholog); FOUND IN photoreceptor inner segment; photoreceptor outer segment; stereocilium; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 1 | 105831719 | 105880082 | Rat | 181 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303052 | Usp11 | ubiquitin specific peptidase 11 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); cysteine-type endopeptidase activity (ortholog); transcription corepressor binding (ortholog); INVOLVED IN protein deubiquitination (ortholog); ASSOCIATED WITH bronchiectasis (ortholog); FOUND IN cytosol (ortholog); nu cleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 6-propyl-2-thiouracil | X | 4026865 | 4043036 | Rat | 93 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1311825 | Usp14 | ubiquitin specific peptidase 14 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); deubiquitinase activity (ortholog); endopeptidase inhibitor activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); inflammatory response (ortholog); negative regulation of ERAD pathway (ortholog); ASSOCIATED WITH distal arthrogryposis (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); cytoplasmic vesicle (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene | 18 | 1292745 | 1330867 | Rat | 151 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308103 | Usp39 | ubiquitin specific peptidase 39 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); spliceosomal complex assembly (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Neoplasms (ortholog); FOU ND IN nucleoplasm (ortholog); nucleus (ortholog); U4/U6 x U5 tri-snRNP complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 4 | 105932140 | 105964551 | Rat | 95 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1311341 | Utp4 | UTP4 small subunit processome component | INVOLVED IN maturation of SSU-rRNA (ortholog); regulation of DNA-templated transcription (ortholog); ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH cholestasis (ortholog); North American Indian Childhood Cirrhosis (ortholog); primary bilia ry cholangitis (ortholog); FOUND IN chromosome (ortholog); fibrillar center (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 19 | 51696437 | 51730323 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311542 | Vasp | vasodilator-stimulated phosphoprotein | ENCODES a protein that exhibits identical protein binding (ortholog); profilin binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament polymerization (ortholog); axon guidance (ortholog); PARTICIPATES IN E-cadherin signaling pathway; Fc gamma receptor mediated sign aling pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN glutamatergic synapse; postsynapse; cell junction (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 88038026 | 88053783 | Rat | 237 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1311653 | Vgll4 | vestigial-like family member 4 | INVOLVED IN negative regulation of cardiac muscle cell proliferation (ortholog); negative regulation of cell growth (ortholog); negative regulation of DNA-templated transcription (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodio xine; amphetamine | 4 | 149598151 | 149711186 | Rat | 121 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307048 | Vil1 | villin 1 | ENCODES a protein that exhibits actin filament binding (ortholog); calcium ion binding (ortholog); cysteine-type endopeptidase inhibitor activity involved in apoptotic process (ortholog); INVOLVED IN actin filament capping (ortholog); actin filament depolymerization (ortholog); actin filament polyme rization (ortholog); ASSOCIATED WITH cerebrotendinous xanthomatosis (ortholog); cholestasis (ortholog); FOUND IN actin filament bundle (ortholog); brush border (ortholog); filopodium (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 3,3',5,5'-tetrabromobisphenol A | 9 | 83440248 | 83467963 | Rat | 196 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304653 | Vma22 | vacuolar ATPase assembly factor VMA22 | INVOLVED IN cellular response to increased oxygen levels (ortholog); intracellular iron ion homeostasis (ortholog); lysosomal lumen acidification (ortholog); ASSOCIATED WITH congenital disorder of glycosylation Ii (ortholog); congenital disorder of glycosylation type IIo (ortholog); genetic disease (ortholog); FOUND IN COPI-coated vesicle (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum-Golgi intermediate compartment (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; acrylamide | 9 | 44146287 | 44150250 | Rat | 67 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 15003863 | Vmn1r83 | vomeronasal 1 receptor 83 | | | | | Rat | | old_protein_id | gene, protein-coding |
| 1310075 | Vnn1 | vanin 1 | ENCODES a protein that exhibits pantetheine hydrolase activity (ortholog); INVOLVED IN acute inflammatory response (ortholog); cell-cell adhesion (ortholog); chronic inflammatory response (ortholog); PARTICIPATES IN pantothenic acid metabolic pathway; ASSOCIATED WITH atopic dermatitis (ortholog); ce liac disease (ortholog); Dyslipidemias (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 23356324 | 23366629 | Rat | 257 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305257 | Vom1r108 | vomeronasal 1 receptor 108 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); pheromone receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); response to pheromone (inferred); sensory perception of chemical stimulus (inferred); FOUND IN membrane (inferr ed); plasma membrane (inferred); INTERACTS WITH furan | 7 | 14726626 | 14727546 | Rat | 12 | UniProt , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 11394442 | Vom1r113 | vomeronasal 1 receptor 113 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); pheromone receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); response to pheromone (inferred); sensory perception of chemical stimulus (inferred); FOUND IN membrane (inferr ed); plasma membrane (inferred); INTERACTS WITH bisphenol A; valproic acid (ortholog) | 1 | 81525720 | 81531043 | Rat | 13 | UniProt | gene, protein-coding, MODEL [RefSeq] |
| 1359358 | Vom1r58 | vomeronasal 1 receptor 58 | INTERACTS WITH 3,4-methylenedioxymethamphetamine | 1 | 83061916 | 83068332 | Rat | 1 | UniProt , old_protein_id | gene, protein-coding, MODEL [RefSeq] |
| 1549777 | Vom1r71 | vomeronasal 1 receptor 71 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); pheromone receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); response to pheromone (inferred); sensory perception of chemical stimulus (inferred); FOUND IN membrane (inferr ed); plasma membrane (inferred); INTERACTS WITH cadmium dichloride; trichloroethene | 4 | 87867022 | 87867924 | Rat | 13 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1560045 | Vom2r52l1 | vomeronasal 2 receptor, 52 like 1 | | | | | Rat | | old_protein_id , UniProt Secondary | gene, protein-coding |
| 1359414 | Vps16 | VPS16 core subunit of CORVET and HOPS complexes | ENCODES a protein that exhibits actin filament binding; actin binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagosome-lysosome fusion (ortholog); endosome to lysosome transport (ortholog); ASSOCIATED WITH dystonia 30 (ortholog); genet ic disease (ortholog); neuropathy (ortholog); FOUND IN axon; endosome; neuronal cell body; INTERACTS WITH 2,6-dinitrotoluene; acrylamide; bisphenol A | 3 | 138075649 | 138097154 | Rat | 119 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311556 | Vps18 | VPS18 core subunit of CORVET and HOPS complexes | ENCODES a protein that exhibits actin binding (ortholog); molecular adaptor activity (ortholog); syntaxin binding (ortholog); INVOLVED IN autophagosome-lysosome fusion (ortholog); endosome organization (ortholog); endosome to lysosome transport (ortholog); FOUND IN presynapse; actin filament (orthol og); AP-3 adaptor complex (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 3 | 126733276 | 126744130 | Rat | 123 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560016 | Vps37a | VPS37A subunit of ESCRT-I | INVOLVED IN ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (ortholog); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH hereditary spastic paraplegia (ortholog); hereditary spastic paraplegia 53 (ortholog); transverse myelitis (ortholog); FOUND IN ESCRT I complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 16 | 58434802 | 58478777 | Rat | 87 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305969 | Vps4b | vacuolar protein sorting 4 homolog B | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN angiogenesis (ortholog); canonical Wnt signaling pathway (ortholog); central nervous system development (ortholog); PARTICIPATES IN endo cytosis pathway; FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 13 | 23421758 | 23446848 | Rat | 124 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306121 | Vps72 | vacuolar protein sorting 72 homolog | ENCODES a protein that exhibits histone binding (ortholog); histone chaperone activity (ortholog); INVOLVED IN positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); somatic stem cell population maintenance (ortholog); PARTICIP ATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN nuclear speck (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol | 2 | 185367329 | 185379199 | Rat | 82 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306069 | Vrk1 | VRK serine/threonine kinase 1 | ENCODES a protein that exhibits histone binding (ortholog); histone H2AX kinase activity (ortholog); histone H3S10 kinase activity (ortholog); INVOLVED IN Cajal body organization (ortholog); chromatin remodeling (ortholog); DNA damage response (ortholog); ASSOCIATED WITH autosomal recessive distal h ereditary motor neuronopathy 10 (ortholog); genetic disease (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN Cajal body (ortholog); chromatin (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 6 | 130679400 | 130746089 | Rat | 163 | old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1549692 | Vrk3 | VRK serine/threonine kinase 3 | ENCODES a protein that exhibits protein phosphatase activator activity (ortholog); protein phosphatase binding (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade (ortholog); skeletal muscle tissue development (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (R,R,R)-alpha-tocopherol; 2,4-dinitrotoluene; bisphenol A | 1 | 104379903 | 104407278 | Rat | 88 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1564659 | Vsig4 | V-set and immunoglobulin domain containing 4 | ENCODES a protein that exhibits complement component C3b binding (ortholog); INVOLVED IN negative regulation of complement activation, alternative pathway (ortholog); negative regulation of interleukin-2 production (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH a cute myeloid leukemia (ortholog); COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN protein-containing complex (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; acetamide; aflatoxin B1 | X | 65154422 | 65179708 | Rat | 73 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310423 | Vstm4 | V-set and transmembrane domain containing 4 | INVOLVED IN endothelial cell migration (ortholog); endothelial cell proliferation (ortholog); retina blood vessel maintenance (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 16 | 8126630 | 8206556 | Rat | 63 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304961 | Wbp1 | WW domain binding protein 1 | ENCODES a protein that exhibits WW domain binding (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; bisphenol A | 4 | 117182880 | 117185279 | Rat | 73 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305793 | Wbp1l | WW domain binding protein 1-like | ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN CXCL12-activated CXCR4 signaling pathway (ortholog); hemopoiesis (ortholog); positive regulation of protein ubiquitination (ortholog); ASSOCIATED WITH nevoid basal cell carcinoma syndrome (ortholog); FOUND IN me mbrane (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 255413701 | 255470026 | Rat | 80 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1305996 | Wdfy1 | WD repeat and FYVE domain containing 1 | ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog); INVOLVED IN positive regulation of toll-like receptor 3 signaling pathway (ortholog); positive regulation of toll-like receptor 4 signaling pathway (ortholog); FOUND IN cytosol (ortholog); early endosome (ortholog); nucleus ( ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; bisphenol A | 9 | 88459613 | 88541215 | Rat | 113 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1306363 | Wdr41 | WD repeat domain 41 | ENCODES a protein that exhibits GTPase activator activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN regulation of autophagy (ortholog); FOUND IN cytoplasm (ortholog); guanyl-nucleotide exchange factor complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzod ioxine; bisphenol A; furan | 2 | 27957453 | 28008573 | Rat | 66 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1306429 | Wdr73 | WD repeat domain 73 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN cytoplasmic microtubule organization (ortholog); nucleus organization (ortholog); ASSOCIATED WITH dystonia (ortholog); epilepsy (ortholog); Galloway-Mowat syndrome (ortholog); FOUND IN cleavage furrow (ort holog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate | 1 | 144269561 | 144277707 | Rat | 68 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303042 | Wfdc15b | WAP four-disulfide core domain 15B | ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH acetamide; amphetamine; bisphenol A | 3 | 173308835 | 173318772 | Rat | 12 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303147 | Wfdc21 | WAP four-disulfide core domain 21 | ENCODES a protein that exhibits enzyme activator activity (ortholog); INVOLVED IN response to lipopolysaccharide (ortholog); response to tumor necrosis factor (ortholog); white fat cell differentiation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Neoplastic Cell Transformatio n (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 4,4'-diaminodiphenylmethane | 10 | 69125336 | 69131205 | Rat | 113 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307835 | Wsb1 | WD repeat and SOCS box-containing 1 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN protein aggregate center assembly (ortholog); protein K27-linked ubiquitination (ortholog); FOUND IN cytoplasm (ortholog); Lewy body (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxin e; 2,4-dinitrotoluene | 10 | 64700752 | 64717038 | Rat | 145 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359599 | Wsb2 | WD repeat and SOCS box-containing 2 | INVOLVED IN intracellular signal transduction (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 12 | 44878483 | 44899474 | Rat | 89 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1311734 | Wwp1 | WW domain containing E3 ubiquitin protein ligase 1 | ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein ubiquitina tion (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; endocytosis pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Prostatic Neoplasms (ortholog); Wolff-Parkinson-White syndrome (ortholog); FOUND IN anchoring junction (inferred); cytoplasm (inferred); cytosol (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 5 | 37889280 | 37982743 | Rat | 115 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310091 | Wwp2 | WW domain containing E3 ubiquitin protein ligase 2 | ENCODES a protein that exhibits potassium channel inhibitor activity (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); transcription regulator inhibitor activity (ortholog); INVOLVED IN extracellular transport (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of potassium ion export across plasma membrane (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Knee Osteoarthritis (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 19 | 52256563 | 52380967 | Rat | 112 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559609 | Wwtr1 | WW domain containing transcription regulator 1 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); transcription coactivator activity (ortholog); transcription coregulator activity (ortholog); INVOLVED IN cilium assembly (ortholog); glomerulus development (ortholog); heart process (ortholog); ASSOCIATED WITH alveolar rh abdomyosarcoma (ortholog); muscular atrophy (ortholog); nephronophthisis (ortholog); FOUND IN nucleus; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 2 | 143801181 | 143916941 | Rat | 224 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359335 | Xkr5 | XK related 5 | FOUND IN plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 77577387 | 77595377 | Rat | 65 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359573 | Xrcc4 | X-ray repair cross complementing 4 | ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (ortholog); DNA binding (ortholog); enzyme binding (ortholog); INVOLVED IN cellular response to lithium ion; base-excision repair (ortholog); central nervous system development (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH Chromosome Aberrations (ortholog); Desbuquois dysplasia (ortholog); genetic disease (ortholog); FOUND IN chromosome, telomeric region (ortholog); condensed chromosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; atrazine | 2 | 22686506 | 22932929 | Rat | 209 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305741 | Yeats4 | YEATS domain containing 4 | ENCODES a protein that exhibits histone H3K18ac reader activity (ortholog); histone H3K27ac reader activity (ortholog); INVOLVED IN gene expression (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); regulation of cell cycle (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; ASSOCIATED WITH high grade glioma; liposarcoma (ortholog); FOUND IN NuA4 histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide | 7 | 54744220 | 54751361 | Rat | 83 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308932 | Ythdf1 | YTH N6-methyladenosine RNA binding protein F1 | ENCODES a protein that exhibits N6-methyladenosine-containing RNA reader activity (ortholog); ribosome binding (ortholog); INVOLVED IN learning (ortholog); memory (ortholog); mRNA destabilization (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); idiopathic pulmonary fibrosis (ortholog); mult iple myeloma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); P-body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 3 | 188402228 | 188417740 | Rat | 132 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308632 | Zbbx | zinc finger, B-box domain containing | ENCODES a protein that exhibits zinc ion binding (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; aflatoxin B1 (ortholog) | 2 | 162134252 | 162245538 | Rat | 26 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307143 | Zbtb17 | zinc finger and BTB domain containing 17 | ENCODES a protein that exhibits core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN ectoderm development (ortholog); G1 to G0 transition (ortholog); gastrulation with mouth fo rming second (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; FOUND IN nucleus (ortholog); protein-containing complex (ortholog); protein-DNA complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 159036482 | 159057580 | Rat | 101 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1310287 | Zbtb43 | zinc finger and BTB domain containing 43 | ENCODES a protein that exhibits RNA polymerase III general transcription initiation factor binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN nucleus (inferred); INTERACTS WIT H 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene | 3 | 37142210 | 37161524 | Rat | 90 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311970 | Zc2hc1a | zinc finger, C2HC-type containing 1A | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acetamide; bisphenol A | 2 | 96194665 | 96231957 | Rat | 71 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310458 | Zc3h8 | zinc finger CCCH type containing 8 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negativ e regulation of T cell differentiation in thymus (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN Cajal body (ortholog); euchromatin (ortholog); histone locus body (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 136629998 | 136646998 | Rat | 118 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305755 | Zdhhc20 | zDHHC palmitoyltransferase 20 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN DNA damage response (ortholog); peptidyl-L-cysteine S-palmitoylation (ortholog); protein palmitoylation (ortholog); FOUND IN Golgi membrane (ortholog); nucleus (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 15 | 36095624 | 36154546 | Rat | 85 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1561389 | Zdhhc9 | zDHHC palmitoyltransferase 9 | ENCODES a protein that exhibits palmitoyltransferase activity (ortholog); protein-cysteine S-palmitoyltransferase activity (ortholog); Ras palmitoyltransferase activity (ortholog); INVOLVED IN peptidyl-L-cysteine S-palmitoylation (ortholog); positive regulation of cGAS/STING signaling pathway (ortho log); positive regulation of pyroptotic inflammatory response (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A | X | 132230243 | 132266139 | Rat | 105 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309905 | Zfp105 | zinc finger protein 105 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (ortholog); perinuclear region of cytoplasm (orth olog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 8 | 131444692 | 131456159 | Rat | 52 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307638 | Zfp131 | zinc finger protein 131 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN intermediate filament cytoskeleton (ortholog); nuc leoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 2 | 53457893 | 53486348 | Rat | 83 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1566283 | Zfp133 | zinc finger protein 133 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH bisphenol A; decabromodiphenyl eth er; gentamycin | 3 | 152282744 | 152300892 | Rat | 48 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1560188 | Zfp14 | ZFP14 zinc finger protein | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN blastocyst hatching (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 1 | 94396055 | 94413338 | Rat | 68 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1359259 | Zfp219 | zinc finger protein 219 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN limb bud formation (ortholog); negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 15 | 27169335 | 27183555 | Rat | 124 | UniProt , old_protein_id | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564726 | Zfp341 | zinc finger protein 341 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity (ortholog); INVOLVED IN DNA-templated transcription (inferred); mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH autosomal recessive hyper-IgE syndrome 3 with re current infections (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); 2,2',4,4'-Tetrabromodiphenyl ether (ortholog) | 3 | 163582937 | 163616448 | Rat | 64 | UniProt , old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1305636 | Zfp410 | zinc finger protein 410 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN negative regulation of gene expression (ortholog); positive re gulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 6 | 109695223 | 109721369 | Rat | 82 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, VALIDATED [RefSeq] |
| 1310179 | Zfp593 | zinc finger protein 593 | ENCODES a protein that exhibits preribosome binding (ortholog); zinc ion binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ort holog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 5 | 151746396 | 151748724 | Rat | 85 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559850 | Zfp637 | zinc finger protein 637 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN DNA-templated transcription (inferred); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; ammonium chloride | 4 | 152656937 | 152682499 | Rat | 66 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307948 | Zfp64 | zinc finger protein 64 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN mesenchymal cell differentiation (ortholog); positive regulation of mRNA splicing, via spliceosome (ortholog); FOUND IN cytoplasm (ortholog); megasporocyte nucleus (ortholog ); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 178085604 | 178114557 | Rat | 80 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308150 | Zfp691 | zinc finger protein 691 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); FOUND IN nucleus (inferred); INTERACTS WITH acrylamide; bisphenol A; dibutyl phthalate | 5 | 138065576 | 138070269 | Rat | 50 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309564 | Zfp819 | zinc finger protein 819 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; caffeine | 1 | 103163570 | 103222203 | Rat | 30 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304879 | Zfp956 | zinc finger protein 956 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleus (inferred); INTERACTS WITH 4,4'-sulfonyldiphen ol; acrylamide; bisphenol A | 4 | 78274206 | 78298178 | Rat | 20 | old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305753 | Zkscan3 | zinc finger with KRAB and SCAN domains 3 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN lysosome organization (ortholog); negative regulation of autophagy (ortholog); negative regulation of cellular senescence (ortholog); ASSOCIATED WIT H Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 17 | 47912816 | 47928553 | Rat | 87 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1303252 | Zmynd11 | zinc finger, MYND-type containing 11 | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); histone H3K36me3 reader activity (ortholog); transcription corepressor activity (ortholog); INVOLVED IN defense response to virus (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); negative re gulation of extrinsic apoptotic signaling pathway (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 1 (ortholog); autosomal dominant intellectual developmental disorder 30 (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; clofibric acid | 17 | 65226907 | 65323278 | Rat | 122 | UniProt | gene, protein-coding, VALIDATED [RefSeq] |
| 1307918 | Znhit2 | zinc finger, HIT-type containing 2 | ENCODES a protein that exhibits zinc ion binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 1 | 212783584 | 212784865 | Rat | 59 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308723 | Znhit6 | zinc finger, HIT-type containing 6 | ENCODES a protein that exhibits ATPase binding (ortholog); enzyme binding (ortholog); identical protein binding (ortholog); INVOLVED IN box C/D snoRNP assembly (ortholog); protein complex oligomerization (ortholog); snoRNA localization (ortholog); FOUND IN pre-snoRNP complex (ortholog); INTERACTS WI TH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 2 | 237147014 | 237178279 | Rat | 88 | UniProt | gene, protein-coding, PROVISIONAL [RefSeq] |