Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | affects expression | ISO | Ing5 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of ING5 mRNA | CTD | PMID:22206623 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Ing5 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Ing5 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ing5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ING5 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ING5 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | ING5 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ING5 mRNA | CTD | PMID:29704546 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ING5 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ING5 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ING5 mRNA | CTD | PMID:28628672 | acrolein | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ING5 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ING5 mRNA | CTD | PMID:32699268 | afimoxifene | affects response to substance | ISO | ING5 (Homo sapiens) | 6480464 | ING5 gene affects the susceptibility to afimoxifene | CTD | PMID:21482774 | aflatoxin B1 | increases expression | ISO | Ing5 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of ING5 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | ISO | ING5 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ING5 gene | CTD | PMID:28458013 | aflatoxin B1 | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ING5 mRNA | CTD | PMID:21641981 | Aflatoxin B2 alpha | decreases methylation | ISO | ING5 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of ING5 intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ING5 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ING5 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ING5 mRNA | CTD | PMID:32699268 | aristolochic acid A | increases expression | ISO | ING5 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of ING5 mRNA | CTD | PMID:33212167 | arsenous acid | increases expression | ISO | ING5 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ING5 mRNA | CTD | PMID:20458559 | benzene | increases expression | ISO | ING5 (Homo sapiens) | 6480464 | Benzene results in increased expression of ING5 mRNA | CTD | PMID:19162166 | benzo[a]pyrene | multiple interactions | ISO | Ing5 (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to ING5 promoter] | CTD | PMID:19654925 | benzo[a]pyrene | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ING5 mRNA | CTD | PMID:26238291 | bis(2-ethylhexyl) phthalate | increases expression | ISO | Ing5 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of ING5 mRNA | CTD | PMID:37810885 | bisphenol A | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ING5 mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | ISO | Ing5 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ING5 mRNA | CTD | PMID:33221593 | bisphenol F | decreases methylation | ISO | ING5 (Homo sapiens) | 6480464 | bisphenol F results in decreased methylation of ING5 gene | CTD | PMID:31601247 | butanal | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of ING5 mRNA | CTD | PMID:26079696 | caffeine | decreases phosphorylation | ISO | ING5 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ING5 protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ING5 gene] | CTD | PMID:28238834 | ciguatoxin CTX1B | affects expression | ISO | Ing5 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of ING5 mRNA | CTD | PMID:18353800 | cisplatin | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ING5 mRNA | CTD | PMID:27392435 | copper(II) sulfate | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ING5 mRNA | CTD | PMID:19549813 | coumarin | decreases phosphorylation | ISO | ING5 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of ING5 protein | CTD | PMID:35688186 | dexamethasone | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ING5 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ING5 mRNA | CTD | PMID:28628672 | Di-n-octyl phthalate | increases expression | ISO | Ing5 (Mus musculus) | 6480464 | di-n-octyl phthalate results in increased expression of ING5 mRNA | CTD | PMID:37810885 | diarsenic trioxide | increases expression | ISO | ING5 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ING5 mRNA | CTD | PMID:20458559 | diisononyl phthalate | increases expression | ISO | Ing5 (Mus musculus) | 6480464 | diisononyl phthalate results in increased expression of ING5 mRNA | CTD | PMID:37810885 | dorsomorphin | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ING5 mRNA | CTD | PMID:27188386 | ethyl methanesulfonate | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of ING5 mRNA | CTD | PMID:23649840 | folic acid | decreases expression | ISO | Ing5 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ING5 mRNA | CTD | PMID:25629700 | formaldehyde | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ING5 mRNA | CTD | PMID:23649840 | FR900359 | decreases phosphorylation | ISO | ING5 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of ING5 protein | CTD | PMID:37730182 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ING5 mRNA | CTD | PMID:33387578 | hydrogen peroxide | affects expression | ISO | ING5 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of ING5 mRNA | CTD | PMID:20044591 | indometacin | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ING5 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ING5 mRNA | CTD | PMID:28628672 | methyl methanesulfonate | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of ING5 mRNA | CTD | PMID:23649840 | ozone | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ING5 mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | ISO | Ing5 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ING5 mRNA | CTD | PMID:17562736 | PCB138 | multiple interactions | ISO | Ing5 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | perfluorohexanesulfonic acid | decreases expression | ISO | Ing5 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of ING5 mRNA | CTD | PMID:37995155 | pirinixic acid | decreases expression | ISO | Ing5 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ING5 mRNA | CTD | PMID:23811191 | SB 431542 | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ING5 mRNA | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | ING5 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of ING5 mRNA | CTD | PMID:25895662 | sunitinib | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ING5 mRNA | CTD | PMID:31533062 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ING5 mRNA | CTD | PMID:34492290 | trichostatin A | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ING5 mRNA | CTD | PMID:24935251 | trichostatin A | affects expression | ISO | ING5 (Homo sapiens) | 6480464 | trichostatin A affects the expression of ING5 mRNA | CTD | PMID:28542535 | valproic acid | decreases expression | ISO | Ing5 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of ING5 mRNA | CTD | PMID:20546886 and PMID:21427059 | valproic acid | affects expression | ISO | ING5 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ING5 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ING5 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | ING5 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ING5 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | ISO | ING5 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of ING5 mRNA | CTD | PMID:27188386 | |