Trim5 (tripartite motif-containing 5)

Gene: Trim5 (tripartite motif-containing 5) Rattus norvegicus

Analyze

Symbol:

Trim5

Name:

tripartite motif-containing 5

RGD ID:

1304579

Description:

Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to symbiont; protein K63-linked ubiquitination; and regulation of signal transduction. Predicted to be located in P-body. Predicted to be active in cytosol and nucleoplasm. Predicted to colocalize with omegasome. Orthologous to human TRIM5 (tripartite motif containing 5); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical protein LOC308906; LOC308906; RGD1304579; similar to 9230105E10Rik protein; tripartite motif-containing protein 5

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRIM5 (tripartite motif containing 5)	HGNC	Ensembl, HomoloGene, OMA, OrthoDB, PhylomeDB, Treefam
Mus musculus (house mouse):	Trim5 (tripartite motif-containing 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TRIM5 (tripartite motif containing 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOC733579 (tripartite motif protein TRIM5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TRIM5 (tripartite motif containing 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TRIM6 (tripartite motif containing 6)	HGNC	PhylomeDB
Homo sapiens (human):	TRIM11 (tripartite motif containing 11)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Trim12c (tripartite motif-containing 12C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TRIM5 (tripartite motif containing 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Trim12a (tripartite motif-containing 12A)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Trim5 (tripartite motif-containing 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:194990	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Danio rerio (zebrafish):	si:dkey-219e21.2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Danio rerio (zebrafish):	si:dkey-18p12.4	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Danio rerio (zebrafish):	si:ch211-114c12.5	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Danio rerio (zebrafish):	si:ch73-364h19.2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Danio rerio (zebrafish):	si:ch211-120g10.1	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Caenorhabditis elegans (roundworm):	B0281.8	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Caenorhabditis elegans (roundworm):	ZK1240.5	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Caenorhabditis elegans (roundworm):	ZK1240.9	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Caenorhabditis elegans (roundworm):	nhl-3	Alliance	DIOPT (Ensembl Compara\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ZK1240.8	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Caenorhabditis elegans (roundworm):	ZK1240.3	Alliance	DIOPT (Ensembl Compara\|InParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	168,132,277 - 168,149,263 (-)	NCBI		GRCr8
mRatBN7.2	1	158,720,407 - 158,737,393 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	158,720,410 - 158,814,012 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	166,708,173 - 166,725,110 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	173,888,188 - 173,905,126 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	166,780,756 - 166,797,732 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	169,446,774 - 169,463,760 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	169,446,805 - 169,534,896 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	175,586,814 - 175,603,800 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	162,096,439 - 162,113,409 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	162,190,323 - 162,207,293 (-)	NCBI
Celera	1	156,710,957 - 156,727,926 (-)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

human immunodeficiency virus infectious disease (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3-chloropropane-1,2-diol (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

arsenite(3-) (ISO)

bisphenol A (EXP,ISO)

buspirone (EXP)

cadmium dichloride (EXP)

chlordecone (ISO)

chlorpyrifos (ISO)

cobalt dichloride (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cytarabine (ISO)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

epoxiconazole (ISO)

genistein (ISO)

glafenine (EXP)

lipopolysaccharide (ISO)

mercury dichloride (ISO)

methapyrilene (EXP)

nefazodone (EXP)

nimesulide (EXP)

ozone (ISO)

paracetamol (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

resveratrol (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

Soman (EXP)

succimer (ISO)

sulforaphane (ISO)

sunitinib (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

valdecoxib (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of innate immune response (ISO)

autophagy (ISO)

innate immune response (IBA,ISO)

negative regulation of viral entry into host cell (ISO)

positive regulation of autophagy (IBA)

positive regulation of canonical NF-kappaB signal transduction (IBA,ISO)

positive regulation of DNA-templated transcription (IEA)

positive regulation of MAPK cascade (ISO)

protein K63-linked ubiquitination (ISO)

protein polyubiquitination (IBA)

regulation of lipopolysaccharide-mediated signaling pathway (ISO)

regulation of protein localization (IBA,ISO)

regulation of viral entry into host cell (IBA)

suppression of viral release by host (ISO)

Cellular Component

cytoplasm (IBA,ISO)

cytosol (IBA)

nucleoplasm (IBA)

omegasome (ISO)

P-body (ISO)

Molecular Function

identical protein binding (ISO)

pattern recognition receptor activity (ISO)

protein binding (ISO)

protein homodimerization activity (IBA,ISO)

protein kinase binding (IBA,ISO)

protein-macromolecule adaptor activity (ISO)

transcription coactivator activity (ISO)

ubiquitin protein ligase activity (IBA)

ubiquitin-protein transferase activity (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11331580	PMID:12878161	PMID:17156811	PMID:18248090	PMID:20357094	PMID:21512573	PMID:22493164	PMID:22829933	PMID:23077300	PMID:25127057

Genomics

Comparative Map Data

Trim5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	168,132,277 - 168,149,263 (-)	NCBI		GRCr8
mRatBN7.2	1	158,720,407 - 158,737,393 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	158,720,410 - 158,814,012 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	166,708,173 - 166,725,110 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	173,888,188 - 173,905,126 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	166,780,756 - 166,797,732 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	169,446,774 - 169,463,760 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	169,446,805 - 169,534,896 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	175,586,814 - 175,603,800 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	162,096,439 - 162,113,409 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	162,190,323 - 162,207,293 (-)	NCBI
Celera	1	156,710,957 - 156,727,926 (-)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

TRIM5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	5,588,635 - 5,685,074 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	5,663,195 - 5,938,619 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	5,684,425 - 5,706,304 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	5,641,364 - 5,662,869 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	5,641,368 - 5,662,869	NCBI
Celera	11	5,803,483 - 5,825,436 (-)	NCBI		Celera
Cytogenetic Map	11	p15.4	NCBI
HuRef	11	5,344,050 - 5,365,972 (-)	NCBI		HuRef
CHM1_1	11	5,683,377 - 5,705,274 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	5,647,845 - 5,742,931 (-)	NCBI		T2T-CHM13v2.0

Trim5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	103,912,593 - 103,937,448 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	103,912,593 - 103,937,301 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	104,263,386 - 104,288,254 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	104,263,386 - 104,288,094 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	111,413,000 - 111,436,646 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	104,137,205 - 104,162,054 (-)	NCBI		MGSCv36	mm8
Celera	7	104,635,824 - 104,653,489 (-)	NCBI		Celera
Cytogenetic Map	7	E3	NCBI
cM Map	7	55.69	NCBI

TRIM5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	8,083,611 - 8,123,913 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	8,041,285 - 8,081,595 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	5,798,336 - 5,819,876 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	5,479,033 - 5,754,014 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	5,479,033 - 5,500,758 (-)	Ensembl	panpan1.1		panPan2

LOC733579
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	4,157,290 - 4,170,204 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	4,157,290 - 4,170,233 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	4,724,246 - 4,737,190 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIM5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	61,040,908 - 61,067,815 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	61,040,928 - 61,069,356 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	64,938,737 - 64,966,441 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Trim5
80 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	417
Count of miRNA genes:	234
Interacting mature miRNAs:	268
Transcripts:	ENSRNOT00000023100
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	155866514	200866514	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
9685799	Bp375	Blood pressure QTL 375			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
9685802	Bp376	Blood pressure QTL 376			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	126540680	171540680	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	136830018	181830018	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350408	181759564	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	144267916	172949660	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	156677124	201278233	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	201278233	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	151162512	201278233	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	151162512	201278233	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	123350408	182418476	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	123350408	182418476	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	123350408	182418476	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	151646613	196646613	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	158633083	203633083	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144017057	197814409	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121833674	166833674	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
71118	Thym1	Thymus enlargement QTL 1	10.17	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	115585465	172949803	Rat
631202	Gluco13	Glucose level QTL 13		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	131763437	159756369	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	136745990	163747690	Rat
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	121767634	166767634	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
724550	Thym3	Thymus enlargement QTL 3	7.82	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	156677124	218753816	Rat
2313060	Bss71	Bone structure and strength QTL 71	2.6	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	1	118944747	163944747	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	154561505	199561505	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	156677124	176484451	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	201278233	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144267916	174133260	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	168883176	Rat
1582204	Livw1	Liver weight QTL 1	3.6	0.0003	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	1	155422851	172949803	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	144267353	196383668	Rat

Markers in Region

RH129380

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	158,720,473 - 158,720,689 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	169,446,841 - 169,447,056	NCBI	Rnor6.0
Rnor_5.0	1	175,586,881 - 175,587,096	UniSTS	Rnor5.0
RGSC_v3.4	1	162,096,490 - 162,096,705	UniSTS	RGSC3.4
Celera	1	156,711,008 - 156,711,223	UniSTS
RH 3.4 Map	1	1300.2	UniSTS
Cytogenetic Map	1	q32	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	4	6		31	30	11	4
Low							4	5	74	4	11		4
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC112864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC113720	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235112	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000023100 ⟹ ENSRNOP00000023099

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	158,720,438 - 158,737,393 (-)	Ensembl
Rnor_6.0 Ensembl	1	169,446,805 - 169,463,760 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000030827 ⟹ ENSRNOP00000038739

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	158,795,290 - 158,814,012 (-)	Ensembl
Rnor_6.0 Ensembl	1	169,447,585 - 169,456,098 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000082645 ⟹ ENSRNOP00000073760

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	158,720,410 - 158,808,407 (-)	Ensembl
Rnor_6.0 Ensembl	1	169,447,386 - 169,534,896 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106057 ⟹ ENSRNOP00000084719

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	158,720,418 - 158,736,986 (-)	Ensembl

RefSeq Acc Id:

NM_001014023 ⟹ NP_001014045

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	168,132,293 - 168,149,263 (-)	NCBI
mRatBN7.2	1	158,720,423 - 158,737,393 (-)	NCBI
Rnor_6.0	1	169,446,790 - 169,463,760 (-)	NCBI
Rnor_5.0	1	175,586,814 - 175,603,800 (-)	NCBI
RGSC_v3.4	1	162,096,439 - 162,113,409 (-)	RGD
Celera	1	156,710,957 - 156,727,926 (-)	RGD

Sequence:

show sequence

TGCTGGTGTGGCAGCTGCCCTGAACTACATCATCCTTTCGGTTCTCATCCTGCACCTGAGCAGA
CGTGTGAGGAGTCAGTAGAGTCAGACACAGGATCACAGCAACTATGGCTTCAGAATTCGTGATG
AATTTAAAAGAGGAGGTGACCTGTCCTATCTGCCTGGACCTGATGGTAGAACCTGTGAGTGGAG
ATTGTGGTCACAGCTTCTGCCAAGCCTGCATCACGCTGAACTATGAATCCAGCAAATGCAATCA
GGATGAGTTCATTTGCCCTGTGTGCCGAGTTAGTTACCTGTTTAAGAACCTGAGGCCCAATCGA
CATGTGGCCAACATAGTGCAGAGGCTCAAAGAGTTCAAGTCCAGCCCAGAAGAGGAGCCGAAGG
TGCTTTCTTGTGCAAGGCATGGAGAGAAACTCCAGCTCTTCTGTAAGAAGGACATGATGCCCAT
CTGCTGGCTTTGTGAGCGATCTCAGGAGCACCGTGGACACCAAACAGTTCTCATTGAAGAGGTG
GTCCAGGAGTATAAGGAGAAGCTGCAGGCAGCTCTGCAAAAGCTGATGGCAGACAAGAAAGAAT
TTGAGAACTGGAAAGATGACCTTCAAAAGGAGAGAACTTACTGGCAGAATCAAATACAGAAAGA
TGTGGAAAATGTCCAGTCAGAGTTTAAAGGAATGAGAGATATCATGGACTCTGAGGAGAAGAAG
GAATTGCAGAAGCTGATGCAAGAGAAGGAAGACATTATGAGCAGCCTGGAAGAGTCTGAAAATG
AGTATTCTCAGCAGAGTAAGTTGCTAGGAGACCTCATCTTAGATGTGGAACATCAGTTACAATG
CTCAGCCACGGAAATGCTGCAGGGTGTAGAGAACACCATAAAACGGAGTCATACTTTTTCGATG
AGGAAGCCCAAAACCATCCCCAAGGAACAAAGAAGAGTGTTCCGAGCCCCTGATCTGCAAGGCA
TGCTGCAAGTGTTACAAGAGGTCACAGAGGCCCAACGCTACTGGGTTCAAGTGACGCTGGTTGA
AAGCAACAATCCAAACATTTTCATTACCGCCGACAAAAGACAGATACGATATGAAGACCACCAA
GCAAGACATTTTGCCCGTCCGACTGAAAACTGTCATGCAGGTGTCCTGGGATACCCAGCTATCC
AATCAGGAAAACACTACTGGGAAGTAGATGTGTCTGGAAAAGGTTCTTGGGTTCTGGGATTAAG
TGATGGAAGCTACCTCTTTAATCCAATATTTCGTTCAAATGCAGAAAGACCCCCAAACCCCCCC
TTATTTCGTTTGAATCTTAGTAATGATTCACATTCTCGTTTGAGTCTTAGTAATGATTCACATT
ATCAACCTAAATATGGCTTCTGGGTTATAGGGCTGTGGGGAAATTCTGTGTATAATGCTTTTGA
GGAGTGTACGTTCACAGGCAAGCCCAGTGTGTTGACCCTCTCTCTGATGGTCCGACCCTGTCGT
GTCGGTATTTTCCTCGACTGTGCAGCTGGCACCCTCTCGTTTTACAATATTTCCAACCATGGCA
CTCTTATCTACAGATTCTGTGCAGGTTCCTTTCCTGATAGGGTTTTTCCATATTTTAACCCCAT
GGGAAGTTCAGAGCCATTGACAATATGCTGGCCAGACTCTTAATCTTCACTGTCTCTGTGCATG
GTCTCTGGTCCTGATGTGTATGTCATGTGCCTGAGCTCATCAGCACTATTTTATCGTTTTGTTC
ATGTCTCTAATCTTTCATTGGAAAATATATTCATTTCTCTAGGCCATATTCTCAGTTTCTTGGG
GTATTTTTTGTCTTTGTTTTGTTTTGTTTTTAGGTGAGACTAACAAATCACTTCCCATATAGTC
AAGGACAAATGTCTAGTGCTCACTGCGTAAGATAACACCGATGCAAAATTCCTCTTATTCTTCA
TGCCAGAGATGGAAGGCAAGGCCTTGTGCACGGTGAGGATGTGCTCCACCGCTGAGCTGTTTGC
TTCAGCTGTCATGTCCCTATAACCTCATTCGGCCCATCAATGAAAGATTAAAGAAGGTTCTTCG
ACAACTTGTCTATTCATGCTGAAAATTATATATAGGAGTCTCTGCTTAAGAAATGCACCCTGAG
CTGTAGGCCAAAGAATGAAGGAGAAGCATCACAAGAAGCCTTATCACTGTGACTAAATTAAGTG
ATCATTAAGACTGTGCATCAGTCTTGCCTGGGAGCTCATACCTGCCATCCTGCATCTGGGAAGT
TGTGGCAGGAAGATTGCTGTGTATTTGAAGCCACCCTTGTATAGAGTTAAGAGCCTGCTTAAAA
AAAATAATCAAGAATATGTATAAAAACCACTACTCTATTTTGTTCTAAGAAATAGAATAACTAG
ATTTCAGAATTGCAGGGTTTGGGTCGTTTTCACAATTTGTAAATAAATGTTTACTAAAAATAAA
TGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006229912 ⟹ XP_006229974

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	168,132,277 - 168,148,870 (-)	NCBI
mRatBN7.2	1	158,720,407 - 158,737,011 (-)	NCBI
Rnor_6.0	1	169,446,774 - 169,463,700 (-)	NCBI
Rnor_5.0	1	175,586,814 - 175,603,800 (-)	NCBI

Sequence:

show sequence

CAGCTCCAACCTCAGGGGAACACTACAACTTTCTGTCCCTAACCTTTTTCCTTCCCTTTGGGCC
ACACTTGCCACCAAGGCAAAACCCAGTCTGGAGCTCTGGTGCAAGAGAAACCATGGGGAAGGCT
TTCTTTCCATCACAGGCAGGTTTCCAGAGGATCAGGAACTTGTTTAGTGATTCTGCCCTAAGCC
TGAACAACTGTCTTAGGGAATTCTAGAAACCTCTAAAAAAAACCAGTTAAGTGTGGGAGAGTTT
ATCATACTAGCTCCCCGGAGACAGCCAATGCTGGCCTGAAGAAAACGTCCTCAGCGAGTGGGGG
AGGCAGCTCATTGGTCGGTCGAGTTGTGGTTTCTCTTTCATTTCCAGCGCTCAAACTTTGGTTC
CTCTTAGAGTGGGGTCTTAAGTATCTTGAAATTCTGGATTAGCGAGTTAATTTTCTGTGATTTA
CGAATTCTCGGTGTCTGAAAGCCGGTGGAACAATTTTAGGGAGCAAAGTTTTGAGGACTTTGGA
AGGAAAACATTGCTTTTGCTTGGGCACCTGAGCAGACGTGTGAGGAGTCAGTAGAGTCAGACAC
AGGATCACAGCAACTATGGCTTCAGAATTCGTGATGAATTTAAAAGAGGAGGTGACCTGTCCTA
TCTGCCTGGACCTGATGGTAGAACCTGTGAGTGGAGATTGTGGTCACAGCTTCTGCCAAGCCTG
CATCACGCTGAACTATGAATCCAGCAAATGCAATCAGGATGAGTTCATTTGCCCTGTGTGCCGA
GTTAGTTACCTGTTTAAGAACCTGAGGCCCAATCGACATGTGGCCAACATAGTGCAGAGGCTCA
AAGAGTTCAAGTCCAGCCCAGAAGAGGAGCCGAAGGTGCTTTCTTGTGCAAGGCATGGAGAGAA
ACTCCAGCTCTTCTGTAAGAAGGACATGATGCCCATCTGCTGGCTTTGTGAGCGATCTCAGGAG
CACCGTGGACACCAAACAGTTCTCATTGAAGAGGTGGTCCAGGAGTATAAGGAGAAGCTGCAGG
CAGCTCTGCAAAAGCTGATGGCAGACAAGAAAGAATTTGAGAACTGGAAAGATGACCTTCAAAA
GGAGAGAACTTACTGGCAGAATCAAATACAGAAAGATGTGGAAAATGTCCAGTCAGAGTTTAAA
GGAATGAGAGATATCATGGACTCTGAGGAGAAGAAGGAATTGCAGAAGCTGATGCAAGAGAAGG
AAGACATTATGAGCAGCCTGGAAGAGTCTGAAAATGAGTATTCTCAGCAGAGTAAGTTGCTAGG
AGACCTCATCTTAGATGTGGAACATCAGTTACAATGCTCAGCCACGGAAATGCTGCAGGGTGTA
GAGAACACCATAAAACGGAGTCATACTTTTTCGATGAGGAAGCCCAAAACCATCCCCAAGGAAC
AAAGAAGAGTGTTCCGAGCCCCTGATCTGCAAGGCATGCTGCAAGTGTTACAAGAGGTCACAGA
GGCCCAACGCTACTGGGTTCAAGTGACGCTGGTTGAAAGCAACAATCCAAACATTTTCATTACC
GCCGACAAAAGACAGATACGATATGAAGACCACCAAGCAAGACATTTTGCCCGTCCGACTGAAA
ACTGTCATGCAGGTGTCCTGGGATACCCAGCTATCCAATCAGGAAAACACTACTGGGAAGTAGA
TGTGTCTGGAAAAGGTTCTTGGGTTCTGGGATTAAGTGATGGAAGCTACCTCTTTAATCCAATA
TTTCGTTCAAATGCAGAAAGACCCCCAAACCCCCCCTTATTTCGTTTGAATCTTAGTAATGATT
CACATTCTCGTTTGAGTCTTAGTAATGATTCACATTATCAACCTAAATATGGCTTCTGGGTTAT
AGGGCTGTGGGGAAATTCTGTGTATAATGCTTTTGAGGAGTGTACGTTCACAGGCAAGCCCAGT
GTGTTGACCCTCTCTCTGATGGTCCGACCCTGTCGTGTCGGTATTTTCCTCGACTGTGCAGCTG
GCACCCTCTCGTTTTACAATATTTCCAACCATGGCACTCTTATCTACAGATTCTGTGCAGGTTC
CTTTCCTGATAGGGTTTTTCCATATTTTAACCCCATGGGAAGTTCAGAGCCATTGACAATATGC
TGGCCAGACTCTTAATCTTCACTGTCTCTGTGCATGGTCTCTGGTCCTGATGTGTATGTCATGT
GCCTGAGCTCATCAGCACTATTTTATCGTTTTGTTCATGTCTCTAATCTTTCATTGGAAAATAT
ATTCATTTCTCTAGGCCATATTCTCAGTTTCTTGGGGTATTTTTTGTCTTTGTTTTGTTTTGTT
TTTAGGTGAGACTAACAAATCACTTCCCATATAGTCAAGGACAAATGTCTAGTGCTCACTGCGT
AAGATAACACCGATGCAAAATTCCTCTTATTCTTCATGCCAGAGATGGAAGGCAAGGCCTTGTG
CACGGTGAGGATGTGCTCCACCGCTGAGCTGTTTGCTTCAGCTGTCATGTCCCTATAACCTCAT
TCGGCCCATCAATGAAAGATTAAAGAAGGTTCTTCGACAACTTGTCTATTCATGCTGAAAATTA
TATATAGGAGTCTCTGCTTAAGAAATGCACCCTGAGCTGTAGGCCAAAGAATGAAGGAGAAGCA
TCACAAGAAGCCTTATCACTGTGACTAAATTAAGTGATCATTAAGACTGTGCATCAGTCTTGCC
TGGGAGCTCATACCTGCCATCCTGCATCTGGGAAGTTGTGGCAGGAAGATTGCTGTGTATTTGA
AGCCACCCTTGTATAGAGTTAAGAGCCTGCTTAAAAAAAATAATCAAGAATATGTATAAAAACC
ACTACTCTATTTTGTTCTAAGAAATAGAATAACTAGATTTCAGAATTGCAGGGTTTGGGTCGTT
TTCACAATTTGTAAATAAATGTTTACTAAAAATAAATGTTAACTTCATAGCTGTCCAA

hide sequence

RefSeq Acc Id:

XM_039078166 ⟹ XP_038934094

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	168,132,277 - 168,138,230 (-)	NCBI
mRatBN7.2	1	158,720,407 - 158,726,360 (-)	NCBI

RefSeq Acc Id:

XM_063262980 ⟹ XP_063119050

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	168,133,973 - 168,148,877 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014045	(Get FASTA)	NCBI Sequence Viewer
	XP_006229974	(Get FASTA)	NCBI Sequence Viewer
	XP_038934094	(Get FASTA)	NCBI Sequence Viewer
	XP_063119050	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78926	(Get FASTA)	NCBI Sequence Viewer
	EDM18081	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000023099
	ENSRNOP00000023099.4
	ENSRNOP00000073760.1
	ENSRNOP00000084719.1

RefSeq Acc Id:

NP_001014045 ⟸ NM_001014023

- UniProtKB:

Q6AYT1 (UniProtKB/TrEMBL), F7FKX1 (UniProtKB/TrEMBL), A0A0G2K6C7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASEFVMNLKEEVTCPICLDLMVEPVSGDCGHSFCQACITLNYESSKCNQDEFICPVCRVSYLF
KNLRPNRHVANIVQRLKEFKSSPEEEPKVLSCARHGEKLQLFCKKDMMPICWLCERSQEHRGHQ
TVLIEEVVQEYKEKLQAALQKLMADKKEFENWKDDLQKERTYWQNQIQKDVENVQSEFKGMRDI
MDSEEKKELQKLMQEKEDIMSSLEESENEYSQQSKLLGDLILDVEHQLQCSATEMLQGVENTIK
RSHTFSMRKPKTIPKEQRRVFRAPDLQGMLQVLQEVTEAQRYWVQVTLVESNNPNIFITADKRQ
IRYEDHQARHFARPTENCHAGVLGYPAIQSGKHYWEVDVSGKGSWVLGLSDGSYLFNPIFRSNA
ERPPNPPLFRLNLSNDSHSRLSLSNDSHYQPKYGFWVIGLWGNSVYNAFEECTFTGKPSVLTLS
LMVRPCRVGIFLDCAAGTLSFYNISNHGTLIYRFCAGSFPDRVFPYFNPMGSSEPLTICWPDS

hide sequence

RefSeq Acc Id:	XP_006229974 ⟸ XM_006229912
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYT1 (UniProtKB/TrEMBL), F7FKX1 (UniProtKB/TrEMBL), A0A0G2K6C7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASEFVMNLKEEVTCPICLDLMVEPVSGDCGHSFCQACITLNYESSKCNQDEFICPVCRVSYLF KNLRPNRHVANIVQRLKEFKSSPEEEPKVLSCARHGEKLQLFCKKDMMPICWLCERSQEHRGHQ TVLIEEVVQEYKEKLQAALQKLMADKKEFENWKDDLQKERTYWQNQIQKDVENVQSEFKGMRDI MDSEEKKELQKLMQEKEDIMSSLEESENEYSQQSKLLGDLILDVEHQLQCSATEMLQGVENTIK RSHTFSMRKPKTIPKEQRRVFRAPDLQGMLQVLQEVTEAQRYWVQVTLVESNNPNIFITADKRQ IRYEDHQARHFARPTENCHAGVLGYPAIQSGKHYWEVDVSGKGSWVLGLSDGSYLFNPIFRSNA ERPPNPPLFRLNLSNDSHSRLSLSNDSHYQPKYGFWVIGLWGNSVYNAFEECTFTGKPSVLTLS LMVRPCRVGIFLDCAAGTLSFYNISNHGTLIYRFCAGSFPDRVFPYFNPMGSSEPLTICWPDS hide sequence

RefSeq Acc Id:

ENSRNOP00000073760 ⟸ ENSRNOT00000082645

RefSeq Acc Id:

ENSRNOP00000023099 ⟸ ENSRNOT00000023100

RefSeq Acc Id:

ENSRNOP00000038739 ⟸ ENSRNOT00000030827

RefSeq Acc Id:	XP_038934094 ⟸ XM_039078166
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSRNOP00000084719 ⟸ ENSRNOT00000106057

RefSeq Acc Id:	XP_063119050 ⟸ XM_063262980
- Peptide Label:	isoform X3

Protein Domains

B box-type B30.2/SPRY RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K6C7-F1-model_v2	AlphaFold	A0A0G2K6C7	1-511	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690280

Promoter ID:

EPDNEW_R805

Type:

multiple initiation site

Name:

Trim5_1

Description:

tripartite motif-containing 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	169,463,759 - 169,463,819	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304579	AgrOrtholog
BioCyc Gene	G2FUF-58094	BioCyc
Ensembl Genes	ENSRNOG00000017191	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000023100	ENTREZGENE
	ENSRNOT00000023100.6	UniProtKB/TrEMBL
	ENSRNOT00000082645.2	UniProtKB/TrEMBL
	ENSRNOT00000106057.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.920	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7106563	IMAGE-MGC_LOAD
InterPro	B30.2/SPRY_sf	UniProtKB/TrEMBL
	B302	UniProtKB/TrEMBL
	Butyrophylin	UniProtKB/TrEMBL
	ConA-like_dom	UniProtKB/TrEMBL
	SPRY_rcpt	UniProtKB/TrEMBL
	Znf-RING_LisH	UniProtKB/TrEMBL
	Znf_B-box	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
KEGG Report	rno:308906	UniProtKB/TrEMBL
MGC_CLONE	MGC:93716	IMAGE-MGC_LOAD
NCBI Gene	308906	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE TRIM	UniProtKB/TrEMBL
	TRIPARTITE MOTIF-CONTAINING PROTEIN 5	UniProtKB/TrEMBL
Pfam	SPRY	UniProtKB/TrEMBL
	zf-B_box	UniProtKB/TrEMBL
	zf-RING_UBOX	UniProtKB/TrEMBL
PhenoGen	Trim5	PhenoGen
PRINTS	BUTYPHLNCDUF	UniProtKB/TrEMBL
PROSITE	B302_SPRY	UniProtKB/TrEMBL
	ZF_BBOX	UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017191	RatGTEx
SMART	BBOX	UniProtKB/TrEMBL
	RING	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
Superfamily-SCOP	B-box zinc-binding domain	UniProtKB/TrEMBL
	ConA_like_lec_gl	UniProtKB/TrEMBL
	RING/U-box	UniProtKB/TrEMBL
UniProt	A0A0G2K6C7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A0Q7_RAT	UniProtKB/TrEMBL
	F7FKX1	ENTREZGENE, UniProtKB/TrEMBL
	Q6AYT1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-04-23	Trim5	tripartite motif-containing 5	RGD1304579	similar to 9230105E10Rik protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1304579	similar to 9230105E10Rik protein	RGD1304579_predicted	similar to 9230105E10Rik protein (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1304579_predicted	similar to 9230105E10Rik protein (predicted)	LOC308906_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC308906_predicted	similar to 9230105E10Rik protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD