Rwdd2b (RWD domain containing 2B)

Gene: Rwdd2b (RWD domain containing 2B) Rattus norvegicus

Analyze

Symbol:

Rwdd2b

Name:

RWD domain containing 2B

RGD ID:

1305062

Description:

Orthologous to human RWDD2B (RWD domain containing 2B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC304132; RGD1305062; RWD domain-containing protein 2B; similar to open reading frame 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RWDD2B (RWD domain containing 2B)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Rwdd2b (RWD domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rwdd2b (RWD domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RWDD2B (RWD domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RWDD2B (RWD domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rwdd2b (RWD domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LTN1 (listerin E3 ubiquitin protein ligase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RWDD2B (RWD domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rwdd2b (RWD domain containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RWDD3 (RWD domain containing 3)	HGNC	Panther
Alliance orthologs ³
Homo sapiens (human):	RWDD2B (RWD domain containing 2B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rwdd2b (RWD domain containing 2B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rwdd2b (RWD domain containing 2B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG30338	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rwdd2b	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	40,152,139 - 40,166,328 (-)	NCBI		GRCr8
mRatBN7.2	11	26,665,877 - 26,677,986 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	26,665,877 - 26,674,603 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	35,363,925 - 35,372,538 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	28,064,170 - 28,072,783 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	27,253,104 - 27,261,717 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	27,085,708 - 27,094,364 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	27,085,711 - 27,094,364 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	30,711,156 - 30,719,812 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	27,189,244 - 27,197,900 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	27,190,414 - 27,192,840 (-)	NCBI
Celera	11	26,418,325 - 26,426,990 (-)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

acetamide (EXP)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

cadmium dichloride (EXP)

caffeine (EXP)

carbon nanotube (ISO)

cisplatin (ISO)

clofibric acid (EXP)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diethylstilbestrol (EXP)

doxorubicin (ISO)

folic acid (ISO)

FR900359 (ISO)

methoxyacetic acid (EXP)

methylmercury chloride (EXP)

Monobutylphthalate (EXP)

N-nitrosodiethylamine (EXP)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

profenofos (EXP)

prothioconazole (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

rotenone (EXP)

silicon dioxide (ISO)

sodium dodecyl sulfate (ISO)

Soman (EXP)

testosterone (ISO)

trimellitic anhydride (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Rwdd2b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	40,152,139 - 40,166,328 (-)	NCBI		GRCr8
mRatBN7.2	11	26,665,877 - 26,677,986 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	26,665,877 - 26,674,603 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	35,363,925 - 35,372,538 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	28,064,170 - 28,072,783 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	27,253,104 - 27,261,717 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	27,085,708 - 27,094,364 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	27,085,711 - 27,094,364 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	30,711,156 - 30,719,812 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	27,189,244 - 27,197,900 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	27,190,414 - 27,192,840 (-)	NCBI
Celera	11	26,418,325 - 26,426,990 (-)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

RWDD2B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	29,004,384 - 29,019,349 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	29,004,384 - 29,019,360 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	30,376,705 - 30,391,670 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	29,299,951 - 29,313,563 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	29,299,952 - 29,313,554	NCBI
Celera	21	15,560,812 - 15,575,163 (-)	NCBI		Celera
Cytogenetic Map	21	q21.3	NCBI
HuRef	21	15,782,744 - 15,798,035 (-)	NCBI		HuRef
CHM1_1	21	29,940,417 - 29,954,042 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	21	27,367,085 - 27,382,803 (-)	NCBI		T2T-CHM13v2.0

Rwdd2b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	87,230,219 - 87,237,480 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	87,230,295 - 87,237,461 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	87,433,331 - 87,440,592 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	87,433,407 - 87,440,573 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	87,433,576 - 87,440,837 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	87,322,605 - 87,329,742 (-)	NCBI		MGSCv36	mm8
Celera	16	87,625,667 - 87,629,850 (-)	NCBI		Celera
Cytogenetic Map	16	C3.3	NCBI
cM Map	16	49.53	NCBI

Rwdd2b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	28,359,487 - 28,371,678 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	28,363,476 - 28,371,491 (-)	NCBI	ChiLan1.0	ChiLan1.0

RWDD2B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	25,187,346 - 25,205,772 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	20,046,181 - 20,063,361 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	15,436,922 - 15,451,135 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	28,825,419 - 28,838,801 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	28,825,419 - 28,838,801 (-)	Ensembl	panpan1.1		panPan2

RWDD2B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	24,017,573 - 24,034,230 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	24,018,397 - 24,031,147 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	24,010,513 - 24,027,355 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	24,131,144 - 24,148,011 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	24,131,418 - 24,144,988 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	24,081,547 - 24,098,464 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	24,083,221 - 24,100,166 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	24,554,706 - 24,571,592 (-)	NCBI		UU_Cfam_GSD_1.0

Rwdd2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	24,466,941 - 24,478,806 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936500	12,991,167 - 13,001,053 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936500	12,989,064 - 13,000,582 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LTN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	192,363,970 - 192,373,946 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	192,359,972 - 192,374,354 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	202,667,551 - 202,676,583 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RWDD2B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	63,206,863 - 63,213,752 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	63,206,876 - 63,216,793 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666071	5,791,926 - 5,799,949 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rwdd2b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	16,994,234 - 17,004,549 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624745	16,998,155 - 17,004,825 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rwdd2b
96 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	153
Count of miRNA genes:	123
Interacting mature miRNAs:	137
Transcripts:	ENSRNOT00000050902
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598842	Glom10	Glomerulus QTL 10	3.4		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	1	35331169	Rat
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
1641927	Alcrsp10	Alcohol response QTL 10			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	11	8436674	53436674	Rat
724517	Uae18	Urinary albumin excretion QTL 18	3.7		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	16472047	44285911	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat

Markers in Region

D11Rat26

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	26,669,782 - 26,669,935 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	27,089,609 - 27,089,757	NCBI	Rnor6.0
Rnor_5.0	11	30,715,057 - 30,715,205	UniSTS	Rnor5.0
RGSC_v3.4	11	27,193,144 - 27,193,293	RGD	RGSC3.4
RGSC_v3.4	11	27,193,145 - 27,193,293	UniSTS	RGSC3.4
RGSC_v3.1	11	27,193,144 - 27,193,293	RGD
Celera	11	26,422,241 - 26,422,389	UniSTS
RH 3.4 Map	11	153.8	RGD
RH 3.4 Map	11	153.8	UniSTS
RH 2.0 Map	11	492.3	RGD
FHH x ACI Map	11	10.0599	RGD
Cytogenetic Map	11	q11	UniSTS

BE112989

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	26,674,987 - 26,675,149 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	27,094,808 - 27,094,969	NCBI	Rnor6.0
Rnor_5.0	11	30,720,256 - 30,720,417	UniSTS	Rnor5.0
Rnor_5.0	11	30,694,048 - 30,694,209	UniSTS	Rnor5.0
RGSC_v3.4	11	27,198,344 - 27,198,505	UniSTS	RGSC3.4
Celera	11	26,427,434 - 26,427,595	UniSTS
RH 3.4 Map	11	135.7	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH137839

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	26,667,889 - 26,668,054 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	27,087,716 - 27,087,880	NCBI	Rnor6.0
Rnor_5.0	11	30,713,164 - 30,713,328	UniSTS	Rnor5.0
RGSC_v3.4	11	27,191,252 - 27,191,416	UniSTS	RGSC3.4
Celera	11	26,420,333 - 26,420,497	UniSTS
RH 3.4 Map	11	123.5	UniSTS
Cytogenetic Map	11	q11	UniSTS

AW530724

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	26,665,903 - 26,666,106 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	27,085,730 - 27,085,932	NCBI	Rnor6.0
Rnor_5.0	11	30,711,178 - 30,711,380	UniSTS	Rnor5.0
RGSC_v3.4	11	27,189,266 - 27,189,468	UniSTS	RGSC3.4
Celera	11	26,418,347 - 26,418,549	UniSTS
RH 3.4 Map	11	136.5	UniSTS
Cytogenetic Map	11	q11	UniSTS

AU048633

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	26,671,770 - 26,672,022 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	27,091,593 - 27,091,844	NCBI	Rnor6.0
Rnor_5.0	11	30,717,041 - 30,717,292	UniSTS	Rnor5.0
RGSC_v3.4	11	27,195,129 - 27,195,380	UniSTS	RGSC3.4
Celera	11	26,424,225 - 26,424,474	UniSTS
Cytogenetic Map	11	q11	UniSTS

UniSTS:259643

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	26,668,667 - 26,669,475 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	27,088,494 - 27,089,301	NCBI	Rnor6.0
Rnor_5.0	11	30,713,942 - 30,714,749	UniSTS	Rnor5.0
RGSC_v3.4	11	27,192,030 - 27,192,837	UniSTS	RGSC3.4
Celera	11	26,421,111 - 26,421,933	UniSTS
Cytogenetic Map	11	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	4	27	27		27			70	34	20	2
Low		39	30	14	19	14	8	11	4	1	21	9	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088441	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC091390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC161911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000050902 ⟹ ENSRNOP00000039159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	26,665,877 - 26,674,603 (-)	Ensembl
Rnor_6.0 Ensembl	11	27,085,711 - 27,094,364 (-)	Ensembl

RefSeq Acc Id:

NM_001100559 ⟹ NP_001094029

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	40,152,144 - 40,160,800 (-)	NCBI
mRatBN7.2	11	26,665,882 - 26,674,544 (-)	NCBI
Rnor_6.0	11	27,085,708 - 27,094,364 (-)	NCBI
Rnor_5.0	11	30,711,156 - 30,719,812 (-)	NCBI
RGSC_v3.4	11	27,189,244 - 27,197,900 (-)	RGD
Celera	11	26,418,325 - 26,426,990 (-)	RGD

Sequence:

show sequence

GTCTCTCTGGGGGTGAGACCTGAGCTGCGAGCGCATCCAGACTCGGGGTATCGGCAGTGTGGGA
GCCCCAGCTCTCGCTCCTTAGGAACTTCAGATGTCTCAGCATGGTTGAGATGGAGCAGGCAGAG
GCCCAGCTCTCCGAGTTGGACCTCCTGGCCAGTATGTTCCCTGGTGAGAATGAGCTAATAGTGA
ATGACCAACTGGCCTTAGCAGAGCTCAAAGATTGTATTGAGAAGAGGACAATGGAGGGGCGGTC
ATCGAAAGTATACTTTACGATTAATGTGAGCCTGGATTTCAATGAGGCAGCAATGGTGATGTTT
TCTTTGTCTTGCATTCTTCCCTTTAAATACCCTACAGTCCTGCCTGAAATTACAGTGAGATCAG
TATCGCTGAGTAGATCCCAGCAGACTCAGCTGAACACAGATCTGACAGCATACCTGCAGAAGCA
CTGTCTGGGAGAGGTCTGTATCCTGAATGCCACAGAGTGGGTTAAAGAGCATGCCTCTGACTAC
GTCAACAGAGATGCCTCACCCTCCCCGGCCAGGCAAAGCACAGTCCAGCCTGTGGATCTCACGT
TCACGAGGCTCTGGATCTACAGCCATCACATCTACAACAAATGCAAAAGACGAAACATCCTAGA
GTGGGCCAGGGAACTGTCCCTGTCCGGGTTTAGCATGCCTGGGAAACCTGGCGTTGTTTGTGTG
GAAGGCCCACAAAGTGCTTGCGAAGAATTCTGGTCAAGACTCAGAAAACTAAACTGGAAGAGGA
TTTTAATTCGCCATCGAGAAGACATTCCTTTTGACAGTACAACCGAGAAAATGGAGGAACAGAG
GAAATTTTCCATTTTTGAAGAAAAGGCCTTCAATGTCCATGGAGCCAGAGGGAACCACATGGAC
TTTGGTCAGCTGTATCAGTTCTTAAATGCCAGGGGGTGTGGGGATGTGTTTCAGATGTTCTTTG
GCGTGGAAGGACAGTGACTGAGCAGAGGGGAAGTCAGATCTGTTGGCTCTCTGTTCCTCTGTGG
ACCATTTCTTCCCTGAAATTCAATTTCAGTGCTGTTCTAGAATGTTCTAGGGTTGAGATCATGA
GAAGAAAATATAGCTGAAGTGTATCAGTCAGGACAAGCCATGCCTAGGGGGTAGAGAGATGGCT
CAGCGGTTAAGAGCCTTGGCCGCTCTTCCAGAGGTCATGAGTTAGGTTCTCAGCAACCACATGT
TAATGGGATCCAATGCCCTCTTCTGGTGTGTCAGCAACAGCATAAGTCATAAGAAAACAAAACA
AACAAACATAAAACATGGCATGCCTGAGAAAAGAACTGAGTTTCAACTTGTAAACTTTAAATGA
CCAGAGAAGGCTGGAGAATTTAATAACTCAGCGGTTAAGAGCATAGACTGTATCACCAAGGACC
TAAGTTCAGTTTTCAGCACCCATGGTAGGGAGCTCATAACCTCCTGCGAGGGAGGATTCAGTGT
GTCGGATGTACTCTGTCATCAGAGTGCTTGAACATACACTCGTAAATATACTCATAAATATACT
CGGGGTATCAGGTCCCCTGGAGCTGGACTTACAGGAGTTGCCCATTGTGCGTGCTGGGAACCTC
TGCAAGAGCAATGCACTCTTTTAACCACTGGGCCATCTGTACCATTTGGTGGAAATGTGAGCTG
GATATGATGTCACATACTTGTAATCCCAGCATTTGGGAAGTAGAGGCAGGAGGATTGGAAGTTC
AAGGCCAGCTGGGCTATATCATTCTCTGTCCCAAAAAACAAAAACAAAAAAACCCAAAAGTTAT
TCATGCAGAAACTTTTGGAAGACAGATTGTATGTATCAGTAATTTTGGTGGTTCAACTTGCTAT
GCATTTCCAACACTCTTCTTCTGCCTTTACTGAGGAACCTGGAAAAACTGTCTGCTCATCCCCC
TGGCCTCTGTTGCAGCTACATTTGGCTGTGGCACAGGAGTGCAGGATTTCCGGGGATGAATTTG
GTTCTCTTTTTGCCAAGGACACTGAAGTGATGTCAGGAGAAAGGACTGATGGACCAAGATATCT
CAATCTCAGAGAGGCCACTGTACAAGATACCTTGTCATGTGCGGACCCAATGTTAATCCTTGCC
TATCTCCAGACCTTTGAAATAAAGTGAAATTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039088441 ⟹ XP_038944369

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	40,152,139 - 40,166,328 (-)	NCBI
mRatBN7.2	11	26,665,877 - 26,677,986 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001094029	(Get FASTA)	NCBI Sequence Viewer
	XP_038944369	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91390	(Get FASTA)	NCBI Sequence Viewer
	AAI61911	(Get FASTA)	NCBI Sequence Viewer
	EDM10640	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000039159
	ENSRNOP00000039159.3

RefSeq Acc Id:

NP_001094029 ⟸ NM_001100559

- UniProtKB:

B1WBW2 (UniProtKB/TrEMBL), A6JL75 (UniProtKB/TrEMBL), F7F829 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVEMEQAEAQLSELDLLASMFPGENELIVNDQLALAELKDCIEKRTMEGRSSKVYFTINVSLDF
NEAAMVMFSLSCILPFKYPTVLPEITVRSVSLSRSQQTQLNTDLTAYLQKHCLGEVCILNATEW
VKEHASDYVNRDASPSPARQSTVQPVDLTFTRLWIYSHHIYNKCKRRNILEWARELSLSGFSMP
GKPGVVCVEGPQSACEEFWSRLRKLNWKRILIRHREDIPFDSTTEKMEEQRKFSIFEEKAFNVH
GARGNHMDFGQLYQFLNARGCGDVFQMFFGVEGQ

hide sequence

RefSeq Acc Id:

ENSRNOP00000039159 ⟸ ENSRNOT00000050902

RefSeq Acc Id:	XP_038944369 ⟸ XM_039088441
- Peptide Label:	isoform X1
- UniProtKB:	B1WBW2 (UniProtKB/TrEMBL), A6JL75 (UniProtKB/TrEMBL), F7F829 (UniProtKB/TrEMBL)

Protein Domains

RWD

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1WBW2-F1-model_v2	AlphaFold	B1WBW2	1-290	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698022

Promoter ID:

EPDNEW_R8546

Type:

multiple initiation site

Name:

Rwdd2b_1

Description:

RWD domain containing 2B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	27,094,377 - 27,094,437	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305062	AgrOrtholog
BioCyc Gene	G2FUF-22055	BioCyc
Ensembl Genes	ENSRNOG00000001599	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000050902	ENTREZGENE
	ENSRNOT00000050902.4	UniProtKB/TrEMBL
Gene3D-CATH	3.10.110.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7321544	IMAGE-MGC_LOAD
	IMAGE:8368806	IMAGE-MGC_LOAD
InterPro	DUF1115	UniProtKB/TrEMBL
	RWD-domain	UniProtKB/TrEMBL
	UBQ-conjugating_enzyme/RWD	UniProtKB/TrEMBL
	UCP038021_RWD	UniProtKB/TrEMBL
KEGG Report	rno:304132	UniProtKB/TrEMBL
MGC_CLONE	MGC:109476	IMAGE-MGC_LOAD
	MGC:187639	IMAGE-MGC_LOAD
NCBI Gene	304132	ENTREZGENE
PANTHER	PTHR15955	UniProtKB/TrEMBL
	RWD DOMAIN-CONTAINING PROTEIN 2B-RELATED	UniProtKB/TrEMBL
Pfam	DUF1115	UniProtKB/TrEMBL
	RWD	UniProtKB/TrEMBL
PhenoGen	Rwdd2b	PhenoGen
PIRSF	UCP038021_RWDD2	UniProtKB/TrEMBL
PROSITE	RWD	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000001599	RatGTEx
SMART	RWD	UniProtKB/TrEMBL
Superfamily-SCOP	UBQ-conjugat/RWD-like	UniProtKB/TrEMBL
UniProt	A6JL75	ENTREZGENE, UniProtKB/TrEMBL
	B1WBW2	ENTREZGENE
	F7F829	ENTREZGENE, UniProtKB/TrEMBL
	Q5BJP8_RAT	UniProtKB/TrEMBL
UniProt Secondary	B1WBW2	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Rwdd2b	RWD domain containing 2B	RGD1305062	similar to open reading frame 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1305062	similar to open reading frame 5	RGD1305062_predicted	similar to open reading frame 5 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1305062_predicted	similar to open reading frame 5 (predicted)	LOC304132_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC304132_predicted	similar to open reading frame 5 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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