Gene: Cyp46a1 (cytochrome P450, family 46, subfamily a, polypeptide 1)  Rattus norvegicus

Symbol: Cyp46a1
Name: cytochrome P450, family 46, subfamily a, polypeptide 1
Description: ENCODES a protein that exhibits cholesterol 24-hydroxylase activity (ortholog); heme binding (ortholog); INVOLVED IN cholesterol catabolic process (ortholog); xenobiotic metabolic process (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; primary bile acid biosynthetic pathway; ASSOCIATED WITH Alzheimer Disease (ortholog); INTERACTS WITH furan; ketamine; (24S)-24-hydroxycholesterol (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cholesterol 24-hydroxylase; Cyp46a1_predicted; cytochrome P450, family 46, subfamily a, polypeptide 1; cytochrome P450, family 46, subfamily a, polypeptide 1 (predicted); LOC362782
Orthologs: Homo sapiens : CYP46A1 (cytochrome P450, family 46, subfamily A, polypeptide 1)  HGNC
Mus musculus : Cyp46a1 (cytochrome P450, family 46, subfamily a, polypeptide 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map6q32 NCBI
RGSC Genome Assembly v5.06141,412,601 - 141,443,679+NCBI
RGSC Genome Assembly v3.46132,700,554 - 132,731,982+NCBI
Rat Celera Assembly6124,801,923 - 124,833,398+NCBI
Genome Assembly 3.16132,711,108 - 132,737,620+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cyp46a1
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 1306605
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE