4921524L21Rikl (RIKEN cDNA 4921524L21 gene like) - Rat Genome Database

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Gene: 4921524L21Rikl (RIKEN cDNA 4921524L21 gene like) Rattus norvegicus
Analyze
Symbol: 4921524L21Rikl (Ensembl: RGD1560860)
Name: RIKEN cDNA 4921524L21 gene like (Ensembl:similar to ankyrin repeat domain 26)
RGD ID: 1560860
Description: INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine (ortholog); benzo[a]pyrene (ortholog); bisphenol A (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ankyrin repeat domain-containing protein 26; hypothetical protein LOC498767; LOC100912220; LOC498767; RGD1560860; similar to ankyrin repeat domain 26; uncharacterized LOC100912220; uncharacterized protein LOC498767
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81759,503,255 - 59,542,745 (+)NCBIGRCr8
mRatBN7.21754,808,184 - 54,847,675 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1754,808,184 - 54,847,671 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1757,991,152 - 58,030,625 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01761,994,255 - 62,033,728 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01756,161,869 - 56,201,345 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01759,704,207 - 59,747,003 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1759,697,875 - 59,746,966 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01755,530,462 - 55,576,432 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,341,833 - 63,395,368 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1756,187,628 - 56,187,896 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
4921524L21Rikl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81759,503,255 - 59,542,745 (+)NCBIGRCr8
mRatBN7.21754,808,184 - 54,847,675 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1754,808,184 - 54,847,671 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1757,991,152 - 58,030,625 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01761,994,255 - 62,033,728 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01756,161,869 - 56,201,345 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01759,704,207 - 59,747,003 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1759,697,875 - 59,746,966 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01755,530,462 - 55,576,432 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,341,833 - 63,395,368 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1756,187,628 - 56,187,896 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
CCDC144BP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381718,537,800 - 18,625,617 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1718,542,155 - 18,625,447 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl1718,537,800 - 18,625,653 (-)EnsemblGRCh38hg38GRCh38
GRCh371718,441,114 - 18,528,930 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361718,427,447 - 18,469,570 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map17p11.2NCBI
HuRef1718,119,527 - 18,120,483 (-)NCBIHuRef
HuRef1718,308,660 - 18,311,695 (+)NCBIHuRef
HuRef1718,127,995 - 18,128,508 (-)NCBIHuRef
CHM1_11718,450,177 - 18,538,414 (-)NCBICHM1_1
T2T-CHM13v2.01718,484,630 - 18,572,446 (-)NCBIT2T-CHM13v2.0

Variants

.
Variants in 4921524L21Rikl
66 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:63
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000035675
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)175089090860781592Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)175089090860781592Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)175090919660781426Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)175402992960463637Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system nervous system reproductive system
High
Medium 4
Low 3
Below cutoff 3 1 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000035675   ⟹   ENSRNOP00000033796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1759,714,657 - 59,746,752 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077324   ⟹   ENSRNOP00000073533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1759,697,875 - 59,746,966 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091037   ⟹   ENSRNOP00000071433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1754,681,044 - 54,720,740 (-)Ensembl
Rnor_6.0 Ensembl1759,704,751 - 59,746,894 (+)Ensembl
RefSeq Acc Id: NM_001170421   ⟹   NP_001163892
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81759,503,255 - 59,542,745 (+)NCBI
mRatBN7.21754,808,184 - 54,847,675 (+)NCBI
Rnor_6.01759,704,751 - 59,746,898 (+)NCBI
Rnor_5.01755,530,462 - 55,576,432 (-)NCBI
RGSC_v3.41763,341,833 - 63,395,368 (+)RGD
Celera1756,187,628 - 56,187,896 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001163892 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58595 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071433.1
  ENSRNOP00000073533
  ENSRNOP00000073533.2
Reference Protein Sequences
RefSeq Acc Id: NP_001163892   ⟸   NM_001170421
- UniProtKB: B0BMW9 (UniProtKB/TrEMBL),   F7FNN1 (UniProtKB/TrEMBL),   A0A0G2K5R9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000033796   ⟸   ENSRNOT00000035675
RefSeq Acc Id: ENSRNOP00000073533   ⟸   ENSRNOT00000077324
RefSeq Acc Id: ENSRNOP00000071433   ⟸   ENSRNOT00000091037
Protein Domains
DUF3496

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K5R9-F1-model_v2 AlphaFold A0A0G2K5R9 1-405 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700533
Promoter ID:EPDNEW_R11057
Type:multiple initiation site
Name:RGD1560860_1
Description:similar to ankyrin repeat domain 26
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01759,704,722 - 59,704,782EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560860 AgrOrtholog
BioCyc Gene G2FUF-8973 BioCyc
Ensembl Genes ENSRNOG00000026376 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000050332 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077324 ENTREZGENE
  ENSRNOT00000077324.2 UniProtKB/TrEMBL
  ENSRNOT00000091037.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7111099 IMAGE-MGC_LOAD
InterPro C144C UniProtKB/TrEMBL
  DUF3496 UniProtKB/TrEMBL
KEGG Report rno:498767 UniProtKB/TrEMBL
MGC_CLONE MGC:187426 IMAGE-MGC_LOAD
NCBI Gene 498767 ENTREZGENE
PANTHER PTHR22245 UniProtKB/TrEMBL
  RIKEN CDNA 4921524L21 GENE UniProtKB/TrEMBL
Pfam DUF3496 UniProtKB/TrEMBL
PhenoGen 4921524L21Rikl PhenoGen
RatGTEx ENSRNOG00000026376 RatGTEx
  ENSRNOG00000050332 RatGTEx
UniProt A0A0G2K5R9 ENTREZGENE, UniProtKB/TrEMBL
  B0BMW9 ENTREZGENE, UniProtKB/TrEMBL
  F7FNN1 ENTREZGENE
UniProt Secondary F7FNN1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 4921524L21Rikl  RIKEN cDNA 4921524L21 gene like  RGD1560860  similar to ankyrin repeat domain 26  Symbol and Name Changed 1299863 APPROVED
2015-07-29 RGD1560860  similar to ankyrin repeat domain 26  LOC100912220  uncharacterized LOC100912220  Data merged from RGD:6488480 737654 PROVISIONAL
2012-07-05 LOC100912220  uncharacterized LOC100912220      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1560860  similar to ankyrin repeat domain 26   RGD1560860_predicted  similar to ankyrin repeat domain 26 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560860_predicted  similar to ankyrin repeat domain 26 (predicted)  LOC498767  similar to ankyrin repeat domain 26  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498767  similar to ankyrin repeat domain 26      Symbol and Name status set to provisional 70820 PROVISIONAL