Pcbp3 (poly(rC) binding protein 3) - Rat Genome Database

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Gene: Pcbp3 (poly(rC) binding protein 3) Rattus norvegicus
Analyze
Symbol: Pcbp3
Name: poly(rC) binding protein 3
RGD ID: 1307430
Description: Predicted to enable C-rich single-stranded DNA binding activity and mRNA binding activity. Predicted to be involved in regulation of RNA metabolic process and regulation of gene expression. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Orthologous to human PCBP3 (poly(rC) binding protein 3); PARTICIPATES IN iron homeostasis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC294336; poly(rC)-binding protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82011,635,579 - 11,877,721 (+)NCBIGRCr8
mRatBN7.22011,678,218 - 11,878,210 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2011,678,269 - 11,878,210 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2012,374,540 - 12,574,476 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02011,735,523 - 11,935,453 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02012,207,277 - 12,407,227 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02012,429,255 - 12,629,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2012,429,315 - 12,629,981 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02014,590,187 - 14,789,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42012,089,173 - 12,290,273 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12012,089,399 - 12,290,500 (+)NCBI
Celera2013,177,980 - 13,376,670 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease. Bogdan AR, etal., Trends Biochem Sci. 2016 Mar;41(3):274-86. doi: 10.1016/j.tibs.2015.11.012. Epub 2015 Dec 23.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease. Lane DJ, etal., Biochim Biophys Acta. 2015 May;1853(5):1130-44. doi: 10.1016/j.bbamcr.2015.01.021. Epub 2015 Feb 4.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16780588   PMID:22521865   PMID:22658674   PMID:23533145  


Genomics

Comparative Map Data
Pcbp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82011,635,579 - 11,877,721 (+)NCBIGRCr8
mRatBN7.22011,678,218 - 11,878,210 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2011,678,269 - 11,878,210 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2012,374,540 - 12,574,476 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02011,735,523 - 11,935,453 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02012,207,277 - 12,407,227 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02012,429,255 - 12,629,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2012,429,315 - 12,629,981 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02014,590,187 - 14,789,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42012,089,173 - 12,290,273 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12012,089,399 - 12,290,500 (+)NCBI
Celera2013,177,980 - 13,376,670 (+)NCBICelera
Cytogenetic Map20p12NCBI
PCBP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382145,643,725 - 45,942,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2145,643,694 - 45,942,454 (+)EnsemblGRCh38hg38GRCh38
GRCh372147,063,639 - 47,362,364 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362146,094,303 - 46,186,795 (+)NCBINCBI36Build 36hg18NCBI36
Build 342146,094,302 - 46,186,795NCBI
Celera2132,382,957 - 32,473,995 (+)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2132,648,695 - 32,742,937 (+)NCBIHuRef
CHM1_12146,830,711 - 46,923,863 (+)NCBICHM1_1
T2T-CHM13v2.02144,013,409 - 44,318,564 (+)NCBIT2T-CHM13v2.0
Pcbp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391076,597,688 - 76,797,951 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1076,597,691 - 76,797,721 (-)EnsemblGRCm39 Ensembl
GRCm381076,761,854 - 76,962,117 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1076,761,857 - 76,961,887 (-)EnsemblGRCm38mm10GRCm38
MGSCv371076,224,599 - 76,424,692 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361076,205,573 - 76,405,504 (-)NCBIMGSCv36mm8
Celera1077,806,064 - 78,005,944 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Pcbp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540742,377,972 - 42,446,722 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540742,395,149 - 42,447,312 (+)NCBIChiLan1.0ChiLan1.0
PCBP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22241,728,255 - 42,038,925 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12136,597,268 - 36,908,069 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02131,972,644 - 32,282,794 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12145,248,322 - 45,545,909 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2145,450,722 - 45,545,909 (+)Ensemblpanpan1.1panPan2
PCBP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13139,025,744 - 39,275,239 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3139,025,731 - 39,275,239 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3138,255,709 - 38,502,304 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03138,663,161 - 38,912,503 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3138,663,053 - 38,912,503 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13138,526,738 - 38,775,388 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03138,488,787 - 38,736,415 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03139,006,828 - 39,255,345 (+)NCBIUU_Cfam_GSD_1.0
Pcbp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497138,409,485 - 38,577,921 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936778552,961 - 625,524 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936778552,290 - 720,724 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCBP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13208,094,877 - 208,259,369 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113208,060,949 - 208,259,368 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213218,271,388 - 218,334,499 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PCBP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,304,497 - 89,585,037 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605417,572,695 - 17,878,333 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pcbp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474531,037,384 - 31,104,250 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474530,866,883 - 31,104,845 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pcbp3
1429 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:92
Interacting mature miRNAs:113
Transcripts:ENSRNOT00000001675
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804241017617956Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
631265Iresp1Immunoglobin response QTL18.3blood anti-double stranded DNA antibody amount (VT:0004762)serum anti-DNA antibody level (CMO:0001533)20903971913461775Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat

Markers in Region
D20Rat4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22011,730,830 - 11,731,000 (+)MAPPERmRatBN7.2
Rnor_6.02012,482,277 - 12,482,444NCBIRnor6.0
Rnor_5.02014,642,667 - 14,642,834UniSTSRnor5.0
RGSC_v3.42012,141,421 - 12,141,753RGDRGSC3.4
RGSC_v3.42012,141,573 - 12,141,740UniSTSRGSC3.4
RGSC_v3.12012,141,800 - 12,141,967RGD
Celera2013,230,433 - 13,230,600UniSTS
RH 3.4 Map20157.4UniSTS
RH 3.4 Map20157.4RGD
RH 2.0 Map20161.9RGD
SHRSP x BN Map2012.6499RGD
Cytogenetic Map20p12UniSTS
RH129104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22011,878,003 - 11,878,187 (+)MAPPERmRatBN7.2
Rnor_6.02012,629,776 - 12,629,959NCBIRnor6.0
Rnor_5.02014,789,360 - 14,789,543UniSTSRnor5.0
RGSC_v3.42012,290,068 - 12,290,251UniSTSRGSC3.4
Celera2013,376,465 - 13,376,648UniSTS
RH 3.4 Map20157.8UniSTS
Cytogenetic Map20p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 35 11 4 7 4 74 19 36 3
Low 3 8 42 33 12 33 8 11 16 5 8 8
Below cutoff 4 4 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001011945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001842415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005497206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010060648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010060649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC127868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000001675   ⟹   ENSRNOP00000001675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2011,678,276 - 11,878,209 (+)Ensembl
Rnor_6.0 Ensembl2012,429,315 - 12,629,981 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098898   ⟹   ENSRNOP00000082318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2011,678,269 - 11,878,210 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103785   ⟹   ENSRNOP00000076709
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2011,678,281 - 11,878,208 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104059   ⟹   ENSRNOP00000077332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2011,678,301 - 11,878,209 (+)Ensembl
RefSeq Acc Id: NM_001011945   ⟹   NP_001011945
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,782 - 11,877,721 (+)NCBI
mRatBN7.22011,678,276 - 11,878,209 (+)NCBI
Rnor_6.02012,429,310 - 12,629,981 (+)NCBI
Rnor_5.02014,590,187 - 14,789,566 (+)NCBI
RGSC_v3.42012,089,173 - 12,290,273 (+)RGD
Celera2013,177,980 - 13,376,670 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256283   ⟹   XP_006256345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,877,721 (+)NCBI
mRatBN7.22011,678,220 - 11,878,210 (+)NCBI
Rnor_6.02012,429,261 - 12,629,985 (+)NCBI
Rnor_5.02014,590,187 - 14,789,566 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098572   ⟹   XP_038954500
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,674 - 11,877,721 (+)NCBI
mRatBN7.22011,678,220 - 11,878,210 (+)NCBI
RefSeq Acc Id: XM_039098575   ⟹   XP_038954503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,877,721 (+)NCBI
mRatBN7.22011,678,220 - 11,878,210 (+)NCBI
RefSeq Acc Id: XM_039098576   ⟹   XP_038954504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,877,721 (+)NCBI
mRatBN7.22011,678,220 - 11,878,210 (+)NCBI
RefSeq Acc Id: XM_039098577   ⟹   XP_038954505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,569 - 11,877,721 (+)NCBI
mRatBN7.22011,678,223 - 11,878,210 (+)NCBI
RefSeq Acc Id: XM_039098578   ⟹   XP_038954506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,676,960 - 11,877,721 (+)NCBI
mRatBN7.22011,678,223 - 11,878,210 (+)NCBI
RefSeq Acc Id: XM_039098580   ⟹   XP_038954508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,877,721 (+)NCBI
mRatBN7.22011,678,223 - 11,878,210 (+)NCBI
RefSeq Acc Id: XM_039098583   ⟹   XP_038954511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,229 (+)NCBI
mRatBN7.22011,678,222 - 11,876,712 (+)NCBI
RefSeq Acc Id: XM_039098584   ⟹   XP_038954512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,855,472 (+)NCBI
mRatBN7.22011,678,220 - 11,855,960 (+)NCBI
RefSeq Acc Id: XM_039098585   ⟹   XP_038954513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,229 (+)NCBI
mRatBN7.22011,678,226 - 11,876,712 (+)NCBI
RefSeq Acc Id: XM_063279056   ⟹   XP_063135126
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,712 - 11,877,721 (+)NCBI
RefSeq Acc Id: XM_063279057   ⟹   XP_063135127
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,712 - 11,877,721 (+)NCBI
RefSeq Acc Id: XM_063279058   ⟹   XP_063135128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,635,579 - 11,877,721 (+)NCBI
RefSeq Acc Id: XM_063279059   ⟹   XP_063135129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,712 - 11,877,721 (+)NCBI
RefSeq Acc Id: XM_063279060   ⟹   XP_063135130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,712 - 11,877,721 (+)NCBI
RefSeq Acc Id: XM_063279061   ⟹   XP_063135131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,712 - 11,877,721 (+)NCBI
RefSeq Acc Id: XM_063279062   ⟹   XP_063135132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,229 (+)NCBI
RefSeq Acc Id: XM_063279063   ⟹   XP_063135133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,229 (+)NCBI
RefSeq Acc Id: XM_063279064   ⟹   XP_063135134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,359 (+)NCBI
RefSeq Acc Id: XM_063279065   ⟹   XP_063135135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,359 (+)NCBI
RefSeq Acc Id: XR_005497206
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,229 (+)NCBI
mRatBN7.22011,678,222 - 11,876,776 (+)NCBI
RefSeq Acc Id: XR_010060648
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,229 (+)NCBI
RefSeq Acc Id: XR_010060649
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82011,677,681 - 11,876,229 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001011945 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256345 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954500 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954503 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954504 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954505 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954506 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954508 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954511 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954512 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954513 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135126 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135127 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135128 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135129 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135130 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135131 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135132 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135133 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135134 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135135 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79196 (Get FASTA)   NCBI Sequence Viewer  
  EDL97125 (Get FASTA)   NCBI Sequence Viewer  
  EDL97126 (Get FASTA)   NCBI Sequence Viewer  
  EDL97127 (Get FASTA)   NCBI Sequence Viewer  
  EDL97128 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001675
  ENSRNOP00000001675.5
  ENSRNOP00000076709
  ENSRNOP00000076709.1
  ENSRNOP00000077332.1
  ENSRNOP00000082318.1
RefSeq Acc Id: NP_001011945   ⟸   NM_001011945
- UniProtKB: F7F4P9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256345   ⟸   XM_006256283
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y0N5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000001675   ⟸   ENSRNOT00000001675
RefSeq Acc Id: XP_038954503   ⟸   XM_039098575
- Peptide Label: isoform X3
- UniProtKB: F7F4P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954500   ⟸   XM_039098572
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y0N5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954504   ⟸   XM_039098576
- Peptide Label: isoform X4
- UniProtKB: F7F4P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954512   ⟸   XM_039098584
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038954511   ⟸   XM_039098583
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038954505   ⟸   XM_039098577
- Peptide Label: isoform X5
- UniProtKB: A6JKB2 (UniProtKB/TrEMBL),   A0A8I5Y0N5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954506   ⟸   XM_039098578
- Peptide Label: isoform X6
- UniProtKB: A0A8I5Y0N5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954508   ⟸   XM_039098580
- Peptide Label: isoform X9
- UniProtKB: F7F4P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954513   ⟸   XM_039098585
- Peptide Label: isoform X16
RefSeq Acc Id: ENSRNOP00000082318   ⟸   ENSRNOT00000098898
RefSeq Acc Id: ENSRNOP00000076709   ⟸   ENSRNOT00000103785
RefSeq Acc Id: ENSRNOP00000077332   ⟸   ENSRNOT00000104059
RefSeq Acc Id: XP_063135128   ⟸   XM_063279058
- Peptide Label: isoform X5
- UniProtKB: A6JKB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135134   ⟸   XM_063279064
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063135135   ⟸   XM_063279065
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063135132   ⟸   XM_063279062
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063135133   ⟸   XM_063279063
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063135126   ⟸   XM_063279056
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063135127   ⟸   XM_063279057
- Peptide Label: isoform X5
- UniProtKB: A6JKB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135131   ⟸   XM_063279061
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063135129   ⟸   XM_063279059
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063135130   ⟸   XM_063279060
- Peptide Label: isoform X7
Protein Domains
K Homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY48-F1-model_v2 AlphaFold Q6AY48 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701512
Promoter ID:EPDNEW_R12036
Type:initiation region
Name:Pcbp3_1
Description:poly binding protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02012,429,314 - 12,429,374EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307430 AgrOrtholog
BioCyc Gene G2FUF-4198 BioCyc
Ensembl Genes ENSRNOG00000001245 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001675 ENTREZGENE
  ENSRNOT00000001675.5 UniProtKB/TrEMBL
  ENSRNOT00000098898.1 UniProtKB/TrEMBL
  ENSRNOT00000103785.1 UniProtKB/TrEMBL
  ENSRNOT00000104059.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131426 IMAGE-MGC_LOAD
InterPro IPR004087 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  KH_type_1 UniProtKB/TrEMBL
KEGG Report rno:294336 UniProtKB/TrEMBL
MGC_CLONE MGC:94248 IMAGE-MGC_LOAD
NCBI Gene 294336 ENTREZGENE
PANTHER KH DOMAIN CONTAINING RNA BINDING PROTEIN UniProtKB/TrEMBL
  POLY(RC) BINDING PROTEIN 3 UniProtKB/TrEMBL
  POLY(RC)-BINDING PROTEIN 3 UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/TrEMBL
PhenoGen Pcbp3 PhenoGen
PROSITE KH_TYPE_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001245 RatGTEx
SMART SM00322 UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
UniProt A0A8I5Y0N5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y113_RAT UniProtKB/TrEMBL
  A0A8I5ZWT0_RAT UniProtKB/TrEMBL
  A6JKB2 ENTREZGENE, UniProtKB/TrEMBL
  F7F4P9 ENTREZGENE, UniProtKB/TrEMBL
  Q6AY48_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Pcbp3  poly(rC) binding protein 3  Pcbp3_predicted  poly(rC) binding protein 3 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pcbp3_predicted  poly(rC) binding protein 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED