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Gene Ontology Annotations
Gene Ontology AnnotationsBiological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | anterior/posterior axis specification | | ISO | RGD:1557890 | 1624291 | MGI:MGI:3042338|PMID:15004567 | RGD | MGI:MGI:3042338 PMID:15004567 | anterior/posterior axis specification | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | anterior/posterior axis specification | | ISO | RGD:1557890 | 1624291 | MGI:MGI:98658 | RGD | MGI:MGI:3776330 PMID:18241853 | anterior/posterior pattern specification | | ISO | RGD:1557890 | 1624291 | MGI:MGI:1197794|PMID:9501024 | RGD | MGI:MGI:1197794 PMID:9501024 | bone mineralization | | ISO | RGD:1347243 | 1624291 | PMID:19113921 | RGD | PMID:19113921 | bone mineralization | | IEA | Ensembl:ENSP00000370297 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | cell migration involved in gastrulation | | ISO | RGD:1557890 | 1624291 | MGI:MGI:107405 | RGD | MGI:MGI:3042338 PMID:15004567 | cell migration involved in gastrulation | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | cellular response to BMP stimulus | | IEP | | | PMID:16798745 | BHF-UCL | PMID:16798745 | determination of dorsal identity | | ISO | RGD:1347243 | 1624291 | PMID:9660951 | RGD | PMID:9660951 | determination of dorsal identity | | IEA | Ensembl:ENSP00000370297 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | gastrulation | | ISO | RGD:1557890 | 1624291 | MGI:MGI:98658 | RGD | MGI:MGI:3776330 PMID:18241853 | growth plate cartilage chondrocyte proliferation | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | negative regulation of activin receptor signaling pathway | | ISO | RGD:1557890 | 1624291 | MGI:MGI:1858315|PMID:10748465 | RGD | MGI:MGI:1858315 PMID:10748465 | negative regulation of activin receptor signaling pathway | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | negative regulation of activin receptor signaling pathway | | ISO | RGD:1347243 | 1624291 | PMID:9660951 | RGD | PMID:9660951 | negative regulation of BMP signaling pathway | | ISO | RGD:1557890 | 1624291 | MGI:MGI:1101446|PMID:9431803 | RGD | MGI:MGI:1101446 PMID:9431803 | negative regulation of BMP signaling pathway | | ISO | RGD:1557890 | 1624291 | MGI:MGI:1197794|PMID:9501024 | RGD | MGI:MGI:1197794 PMID:9501024 | negative regulation of cell proliferation | | ISO | RGD:1557890 | 1624291 | MGI:MGI:107405 | RGD | MGI:MGI:3042338 PMID:15004567 | negative regulation of cell proliferation | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | negative regulation of mesoderm development | | ISO | RGD:1557890 | 1624291 | MGI:MGI:1858315|PMID:10748465 | RGD | MGI:MGI:1858315 PMID:10748465 | negative regulation of mesoderm development | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | negative regulation of mesoderm development | | ISO | RGD:1347243 | 1624291 | PMID:9660951 | RGD | PMID:9660951 | negative regulation of Wnt receptor signaling pathway | NOT | ISO | RGD:1557890 | 1624291 | MGI:MGI:1858315|PMID:10748465 | RGD | MGI:MGI:1858315 PMID:10748465 | nervous system development | | ISO | RGD:1347243 | 1624291 | PMID:9660951 | RGD | PMID:9660951 | nervous system development | | IEA | Ensembl:ENSP00000370297 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | sequestering of BMP in extracellular matrix | | ISO | RGD:1557890 | 1624291 | MGI:MGI:1858315|PMID:10748465 | RGD | MGI:MGI:1858315 PMID:10748465 | sequestering of BMP in extracellular matrix | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | sequestering of BMP in extracellular matrix | | ISO | RGD:1347243 | 1624291 | PMID:9660951 | RGD | PMID:9660951 | signal transduction involved in regulation of gene expression | | ISO | RGD:1557890 | 1624291 | MGI:MGI:4415813|PMID:18462699 | RGD | MGI:MGI:4415813 PMID:18462699 | signal transduction involved in regulation of gene expression | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | ureteric bud development | | ISO | RGD:1557890 | 1624291 | MGI:MGI:5308475|PMID:22114682 | RGD | MGI:MGI:5308475 PMID:22114682 | ureteric bud development | | IEA | Ensembl:ENSMUSP00000048607 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Wnt signaling pathway |
| Pathway Interaction Database | BMP receptor signaling (PID:200144) |
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| KEGG Pathway | Wnt signaling pathway |
| Pathway Interaction Database | BMP receptor signaling (PID:200144) |
References - curated| 1. |
Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 2. |
RGD automated import pipeline for gene-chemical interactions |
References - uncurated
RGD Disease Portals| Cer1 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Cer1 (Rattus norvegicus) |
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| CER1 (Homo sapiens) |
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| Cer1 (Mus musculus) |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_001115031 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06038329 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHX01038032 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC158726 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473978 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_001115031 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001108503 | ||||||||||||||||||||
| Peptide Label: | precursor | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001108503 | (Get FASTA) |
| GenBank Protein | AAI58727 | (Get FASTA) |
| EDM10464 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000010518 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000014008 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000014008 | ENTREZGENE, UniProtKB/TrEMBL |
| Entrez Gene | 500485 | ENTREZGENE |
| HomoloGene Group ID | 3983 | ENTREZGENE |
| IMAGE_CLONE | IMAGE:9091451 | IMAGE-MGC_LOAD |
| InterPro | Cerberus | UniProtKB/TrEMBL |
| Cys_knot_C | UniProtKB/TrEMBL | |
| DAN | UniProtKB/TrEMBL | |
| IPI | IPI00206243 | UniProtKB/TrEMBL |
| KEGG Report | rno:500485 | ENTREZGENE, UniProtKB/TrEMBL |
| MGC_CLONE | MGC:187879 | IMAGE-MGC_LOAD |
| Pfam | DAN | UniProtKB/TrEMBL |
| PIRSF | Cerberus | UniProtKB/TrEMBL |
| PROSITE | CTCK_2 | UniProtKB/TrEMBL |
| SMART | SM00041 | UniProtKB/TrEMBL |
| UniGene | Rn.195850 | ENTREZGENE |
| UniProt | B0BN87_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2013-03-06 | Cer1 | cerberus 1, DAN family BMP antagonist | Cer1 | cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis) | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2012-10-12 | Cer1 | cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis) | RGD1563046 | similar to cerberus-like | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2008-04-30 | RGD1563046 | similar to cerberus-like | RGD1563046_predicted | similar to cerberus-like (predicted) | 'predicted' is removed | 24709 | APPROVED |
| 2006-03-07 | RGD1563046_predicted | similar to cerberus-like (predicted) | LOC500485 | similar to cerberus-like | Symbol and Name status set to approved | 10779 | APPROVED |
| 2006-02-09 | LOC500485 | similar to cerberus-like | Symbol and Name status set to provisional | 1724 | PROVISIONAL |
| More on Cer1 | |
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Entrez Gene |
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Ensembl Gene |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 1563046 |
| Created: | 2006-02-09 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




