Gene: Smpd1 (sphingomyelin phosphodiesterase 1, acid lysosomal) Rattus norvegicus
Symbol: Smpd1
Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Description: ENCODES a protein that exhibits sphingomyelin phosphodiesterase activity (inferred); INVOLVED IN ceramide biosynthetic process; positive regulation of apoptotic process; response to cocaine; PARTICIPATES IN ceramide signaling pathway; FasL mediated signaling pathway; Trail mediated signaling pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental; Hepatolenticular Degeneration; Niemann-Pick Disease, Type A (ortholog); FOUND IN extracellular space; lamellar body; extracellular vesicular exosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; bezafibrate; clofibric acid
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC94748; sphingomyelin phosphodiesterase
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map1q33 NCBI
RGSC Genome Assembly v5.01177,389,588 - 177,393,431+NCBI
RGSC Genome Assembly v3.41163,278,970 - 163,282,813+NCBI
Rat Celera Assembly1157,825,620 - 157,829,463+NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Smpd1
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1549719
Created: 2005-09-15
Species: Rattus norvegicus
Last Modified: 2014-08-12
Status: ACTIVE