Gene: Smpd1 (sphingomyelin phosphodiesterase 1) Rattus norvegicus
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Symbol: Smpd1
Name: sphingomyelin phosphodiesterase 1
Description: ENCODES a protein that exhibits acid sphingomyelin phosphodiesterase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN ceramide biosynthetic process; positive regulation of apoptotic process; response to cocaine; PARTICIPATES IN ceramide signaling pathway; FasL mediated signaling pathway; Trail mediated signaling pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental; Hepatolenticular Degeneration; Wilson disease; FOUND IN extracellular space; lamellar body; endosome (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; bezafibrate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC94748; sphingomyelin phosphodiesterase; sphingomyelin phosphodiesterase 1, acid lysosomal
Orthologs:
Homo sapiens (human) : SMPD1 (sphingomyelin phosphodiesterase 1)  HGNC  AGR
Mus musculus (house mouse) : Smpd1 (sphingomyelin phosphodiesterase 1, acid lysosomal)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Smpd1 (sphingomyelin phosphodiesterase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SMPD1 (sphingomyelin phosphodiesterase 1)
Canis lupus familiaris (dog) : SMPD1 (sphingomyelin phosphodiesterase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smpd1 (sphingomyelin phosphodiesterase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01170,383,682 - 170,387,525 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01177,389,588 - 177,393,431 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41163,278,970 - 163,282,813 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1157,825,620 - 157,829,463 (+)NCBI
Cytogenetic Map1q32NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Smpd1
AGR Gene
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 1549719
Created: 2005-09-15
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE