Aspn (asporin) - Rat Genome Database

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Gene: Aspn (asporin) Rattus norvegicus
Analyze
Symbol: Aspn
Name: asporin
RGD ID: 1549776
Description: Predicted to enable calcium ion binding activity. Involved in response to fluoride. Located in cell projection. Human ortholog(s) of this gene implicated in ankylosing spondylitis; degenerative disc disease; and osteoarthritis. Orthologous to human ASPN (asporin); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Aspnl1; asporin-like 1; LOC306805; similar to asporin precursor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Note: GeneIDs 103690027 and 306805 are annotated independently on Rnor_6.0 but may be redundant loci. [06 Feb 2015]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81715,286,338 - 15,310,567 (-)NCBIGRCr8
mRatBN7.21715,079,910 - 15,104,369 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1715,080,639 - 15,104,041 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1714,967,831 - 14,991,213 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01716,572,887 - 16,596,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01714,894,622 - 14,918,004 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01714,655,958 - 14,681,355 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1715,495,790 - 15,519,282 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1714,656,009 - 14,679,409 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01716,708,328 - 16,731,849 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01717,554,966 - 17,577,763 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41721,035,597 - 21,058,999 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1714,811,448 - 14,834,831 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-diaminotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
captan  (ISO)
carnosic acid  (ISO)
CGP 52608  (ISO)
crocidolite asbestos  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (EXP,ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
fructose  (ISO)
furan  (EXP)
glucose  (ISO)
herbicide  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
lead diacetate  (EXP)
lidocaine  (EXP)
maneb  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
milrinone  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodimethylamine  (EXP)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenformin  (EXP)
progesterone  (ISO)
rotenone  (EXP)
sodium fluoride  (ISO)
sulforaphane  (ISO)
testosterone enanthate  (ISO)
triadimefon  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc. Gruber HE, etal., Arthritis Res Ther. 2009;11(2):R47. doi: 10.1186/ar2660. Epub 2009 Mar 27.
3. Asporin and the mineralization process in fluoride-treated rats. Houari S, etal., J Bone Miner Res. 2014 Jun;29(6):1446-55.
4. An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Kizawa H, etal., Nat Genet. 2005 Feb;37(2):138-44. Epub 2005 Jan 9.
5. Association of an asporin repeat polymorphism with ankylosing spondylitis in Han Chinese population: a case-control study. Liu D, etal., Clin Invest Med. 2010 Feb 1;33(1):E63-8.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians. Rodriguez-Lopez J, etal., Arthritis Res Ther. 2006;8(3):R55. Epub 2006 Mar 10.
11. Association of the D repeat polymorphism in the ASPN gene with developmental dysplasia of the hip: a case-control study in Han Chinese. Shi D, etal., Arthritis Res Ther. 2011 Feb 17;13(1):R27. doi: 10.1186/ar3252.
12. Association of the asporin D14 allele with lumbar-disc degeneration in Asians. Song YQ, etal., Am J Hum Genet. 2008 Mar;82(3):744-7. doi: 10.1016/j.ajhg.2007.12.017. Epub 2008 Feb 21.
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11152692   PMID:17522060   PMID:17827158   PMID:19589127   PMID:20551380   PMID:22206666   PMID:25038933   PMID:26031659   PMID:27068509   PMID:27559042  


Genomics

Comparative Map Data
Aspn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81715,286,338 - 15,310,567 (-)NCBIGRCr8
mRatBN7.21715,079,910 - 15,104,369 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1715,080,639 - 15,104,041 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1714,967,831 - 14,991,213 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01716,572,887 - 16,596,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01714,894,622 - 14,918,004 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01714,655,958 - 14,681,355 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1715,495,790 - 15,519,282 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1714,656,009 - 14,679,409 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01716,708,328 - 16,731,849 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01717,554,966 - 17,577,763 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41721,035,597 - 21,058,999 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1714,811,448 - 14,834,831 (-)NCBICelera
Cytogenetic Map17p14NCBI
ASPN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38992,456,205 - 92,482,506 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl992,456,205 - 92,482,506 (-)EnsemblGRCh38hg38GRCh38
GRCh37995,218,487 - 95,244,788 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36994,258,308 - 94,284,609 (-)NCBINCBI36Build 36hg18NCBI36
Build 34992,298,045 - 92,324,343NCBI
Celera965,660,507 - 65,686,862 (-)NCBICelera
Cytogenetic Map9q22.31NCBI
HuRef964,895,929 - 64,922,284 (-)NCBIHuRef
CHM1_1995,364,907 - 95,391,264 (-)NCBICHM1_1
T2T-CHM13v2.09104,622,707 - 104,649,005 (-)NCBIT2T-CHM13v2.0
Aspn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391349,697,919 - 49,721,041 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1349,697,919 - 49,721,041 (+)EnsemblGRCm39 Ensembl
GRCm381349,544,443 - 49,567,565 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1349,544,443 - 49,567,565 (+)EnsemblGRCm38mm10GRCm38
MGSCv371349,639,812 - 49,662,934 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361349,556,478 - 49,579,502 (+)NCBIMGSCv36mm8
Celera1350,634,916 - 50,658,050 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1325.31NCBI
Aspn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555155,321,943 - 5,345,894 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555155,322,074 - 5,345,715 (+)NCBIChiLan1.0ChiLan1.0
ASPN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21146,940,895 - 46,972,365 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1946,947,044 - 46,974,751 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0963,579,188 - 63,605,811 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1991,651,621 - 91,677,969 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl991,651,629 - 91,677,969 (-)Ensemblpanpan1.1panPan2
ASPN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1198,881,610 - 98,905,641 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl198,881,690 - 98,904,945 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha199,275,463 - 99,299,478 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0199,498,440 - 99,522,461 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl199,498,487 - 99,545,678 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1199,111,520 - 99,135,540 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0198,846,776 - 98,870,787 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0199,603,543 - 99,627,551 (+)NCBIUU_Cfam_GSD_1.0
Aspn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049447,863,503 - 7,888,007 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364872,079,973 - 2,104,499 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364872,080,014 - 2,104,534 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASPN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl342,165,561 - 42,192,813 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1342,165,553 - 42,192,902 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2343,350,293 - 43,377,638 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASPN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112102,972,652 - 102,999,248 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12102,972,541 - 102,999,368 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603891,244,869 - 91,271,647 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aspn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248683,897,514 - 3,920,383 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248683,897,633 - 3,920,307 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aspn
72 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:13
Count of miRNA genes:13
Interacting mature miRNAs:13
Transcripts:ENSRNOT00000020704
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)17429913021293263Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1581553Pur14Proteinuria QTL 145.30.0001urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)17797996816317111Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)171398677321975515Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 7 3 3 10 1 3
Low 4 40 50 18 38 18 13 15 17 43 27 21 13
Below cutoff 2 31 31 31 1 45 1 6

Sequence


RefSeq Acc Id: ENSRNOT00000020704   ⟹   ENSRNOP00000020704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1715,080,639 - 15,104,041 (-)Ensembl
Rnor_6.0 Ensembl1714,656,009 - 14,679,409 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000074041   ⟹   ENSRNOP00000064616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1715,080,639 - 15,097,195 (-)Ensembl
Rnor_6.0 Ensembl1715,495,801 - 15,511,972 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093577   ⟹   ENSRNOP00000076216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1715,495,790 - 15,519,282 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093624   ⟹   ENSRNOP00000076176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1715,080,639 - 15,096,794 (-)Ensembl
Rnor_6.0 Ensembl1715,499,838 - 15,519,060 (-)Ensembl
RefSeq Acc Id: NM_001014008   ⟹   NP_001014030
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81715,287,065 - 15,310,469 (-)NCBI
mRatBN7.21715,080,637 - 15,104,041 (-)NCBI
Rnor_6.01714,656,007 - 14,679,409 (-)NCBI
Rnor_5.01717,554,966 - 17,577,763 (-)NCBI
RGSC_v3.41721,035,597 - 21,058,999 (-)RGD
Celera1714,811,448 - 14,834,831 (-)RGD
Sequence:
RefSeq Acc Id: XM_006253695   ⟹   XP_006253757
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81715,286,338 - 15,310,567 (-)NCBI
mRatBN7.21715,079,910 - 15,104,369 (-)NCBI
Rnor_6.01714,655,958 - 14,681,355 (-)NCBI
Rnor_5.01716,708,328 - 16,731,849 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001014030 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253757 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83711 (Get FASTA)   NCBI Sequence Viewer  
  EDL98112 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020704
  ENSRNOP00000020704.4
  ENSRNOP00000064616.2
  ENSRNOP00000076176.1
RefSeq Acc Id: NP_001014030   ⟸   NM_001014008
- Peptide Label: precursor
- UniProtKB: Q5XIH1 (UniProtKB/TrEMBL),   A6J6W0 (UniProtKB/TrEMBL),   M0R5F1 (UniProtKB/TrEMBL),   F7F5B0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253757   ⟸   XM_006253695
- Peptide Label: isoform X1
- UniProtKB: Q5XIH1 (UniProtKB/TrEMBL),   A6J6W0 (UniProtKB/TrEMBL),   M0R5F1 (UniProtKB/TrEMBL),   F7F5B0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000020704   ⟸   ENSRNOT00000020704
RefSeq Acc Id: ENSRNOP00000076216   ⟸   ENSRNOT00000093577
RefSeq Acc Id: ENSRNOP00000076176   ⟸   ENSRNOT00000093624
RefSeq Acc Id: ENSRNOP00000064616   ⟸   ENSRNOT00000074041
Protein Domains
LRRNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIH1-F1-model_v2 AlphaFold Q5XIH1 1-375 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700343
Promoter ID:EPDNEW_R10867
Type:single initiation site
Name:Aspnl1_1
Description:asporin-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01714,679,455 - 14,679,515EPDNEW
RGD ID:13700347
Promoter ID:EPDNEW_R10868
Type:multiple initiation site
Name:AC120310_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01714,687,480 - 14,687,540EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1549776 AgrOrtholog
BioCyc Gene G2FUF-9999 BioCyc
Ensembl Genes ENSRNOG00000015410 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000050431 Ensembl
Ensembl Transcript ENSRNOT00000020704 ENTREZGENE
  ENSRNOT00000020704.6 UniProtKB/TrEMBL
  ENSRNOT00000074041.3 UniProtKB/TrEMBL
  ENSRNOT00000093624.2 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7190620 IMAGE-MGC_LOAD
InterPro L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR-contain_N UniProtKB/TrEMBL
  SLRP_I_decor/aspor/byglycan UniProtKB/TrEMBL
KEGG Report rno:306805 UniProtKB/TrEMBL
MGC_CLONE MGC:94601 IMAGE-MGC_LOAD
NCBI Gene 306805 ENTREZGENE
PANTHER AGAP008170-PA UniProtKB/TrEMBL
  PTHR45712:SF2 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
PhenoGen Aspn PhenoGen
PIRSF SLRP_I UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015410 RatGTEx
  ENSRNOG00000050431 RatGTEx
SMART LRR_TYP UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A1W2Q6A1_RAT UniProtKB/TrEMBL
  A6J6W0 ENTREZGENE, UniProtKB/TrEMBL
  F7F5B0 ENTREZGENE, UniProtKB/TrEMBL
  M0R5F1 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIH1 ENTREZGENE
UniProt Secondary Q5XIH1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-06-03 Aspn  asporin  Aspnl1  asporin-like 1  Data merged from RGD:9278606 737654 PROVISIONAL
2021-06-03 Aspnl1  asporin-like 1  Aspnl1  asporin-like 1  Data merged from RGD:9278606 737654 PROVISIONAL
2021-06-03 Aspnl1  asporin-like 1  Aspnl1  asporin-like 1  Data merged from RGD:9278606 737654 PROVISIONAL
2021-06-03 Aspnl1  asporin-like 1  Aspnl1  asporin-like 1  Data merged from RGD:9278606 737654 PROVISIONAL
2021-06-03 Aspnl1  asporin-like 1  Aspnl1  asporin-like 1  Data merged from RGD:9278606 737654 PROVISIONAL
2014-08-25 Aspnl1  asporin-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-04 Aspn  asporin  LOC306805  similar to asporin precursor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-15 LOC306805  similar to asporin precursor      Symbol and Name status set to provisional 70820 PROVISIONAL