Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Colonic Neoplasms | | ISO | PTP4A3 (Homo sapiens) | 11554173 | CTD Direct Evidence: therapeutic | CTD | PMID:23555575 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Colonic Neoplasms | | ISO | PTP4A3 (Homo sapiens) | 11554173 | CTD Direct Evidence: therapeutic | CTD | PMID:23555575 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:12477932 | PMID:17018620 | PMID:20439489 | PMID:23117660 | PMID:23178297 | PMID:24403062 |
Ptp4a3 (Rattus norvegicus - Norway rat) |
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PTP4A3 (Homo sapiens - human) |
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Ptp4a3 (Mus musculus - house mouse) |
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Ptp4a3 (Chinchilla lanigera - long-tailed chinchilla) |
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PTP4A3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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PTP4A3 (Canis lupus familiaris - dog) |
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Ptp4a3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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PTP4A3 (Sus scrofa - pig) |
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PTP4A3 (Chlorocebus sabaeus - green monkey) |
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Ptp4a3 (Heterocephalus glaber - naked mole-rat) |
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Variants in Ptp4a3
47 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 43 | 14 | 6 | 19 | 6 | 8 | 11 | 74 | 25 | 35 | 11 | 8 |
Low | 43 | 35 | 35 | 10 | 6 | ||||||||
Below cutoff |
RefSeq Transcripts | NM_001114405 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006241729 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006241731 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006241732 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006241733 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008765573 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008765574 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594964 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594965 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063263855 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063263856 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | BC159432 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CH473950 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000010224 ⟹ ENSRNOP00000010224 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000096141 ⟹ ENSRNOP00000078100 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001114405 ⟹ NP_001107877 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006241729 ⟹ XP_006241791 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006241731 ⟹ XP_006241793 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006241732 ⟹ XP_006241794 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_008765573 ⟹ XP_008763795 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_008765574 ⟹ XP_008763796 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063263855 ⟹ XP_063119925 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063263856 ⟹ XP_063119926 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001107877 | (Get FASTA) | NCBI Sequence Viewer |
XP_006241791 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006241793 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006241794 | (Get FASTA) | NCBI Sequence Viewer | |
XP_008763795 | (Get FASTA) | NCBI Sequence Viewer | |
XP_008763796 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063119925 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063119926 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAI59433 | (Get FASTA) | NCBI Sequence Viewer |
EDM16108 | (Get FASTA) | NCBI Sequence Viewer | |
EDM16109 | (Get FASTA) | NCBI Sequence Viewer | |
EDM16110 | (Get FASTA) | NCBI Sequence Viewer | |
EDM16111 | (Get FASTA) | NCBI Sequence Viewer | |
EDM16112 | (Get FASTA) | NCBI Sequence Viewer | |
EDM16113 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000010224.5 | ||
ENSRNOP00000078100 | |||
ENSRNOP00000078100.1 |
RefSeq Acc Id: | NP_001107877 ⟸ NM_001114405 |
- UniProtKB: | B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006241793 ⟸ XM_006241731 |
- Peptide Label: | isoform X1 |
- UniProtKB: | B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006241791 ⟸ XM_006241729 |
- Peptide Label: | isoform X1 |
- UniProtKB: | B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006241794 ⟸ XM_006241732 |
- Peptide Label: | isoform X1 |
- UniProtKB: | B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008763795 ⟸ XM_008765573 |
- Peptide Label: | isoform X1 |
- UniProtKB: | B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008763796 ⟸ XM_008765574 |
- Peptide Label: | isoform X1 |
- UniProtKB: | B0K032 (UniProtKB/TrEMBL), A0A8I5Y855 (UniProtKB/TrEMBL), F7EWD1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000010224 ⟸ ENSRNOT00000010224 |
RefSeq Acc Id: | ENSRNOP00000078100 ⟸ ENSRNOT00000096141 |
RefSeq Acc Id: | XP_063119925 ⟸ XM_063263855 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I5Y855 (UniProtKB/TrEMBL), B0K032 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063119926 ⟸ XM_063263856 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I5Y855 (UniProtKB/TrEMBL), B0K032 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-B0K032-F1-model_v2 | AlphaFold | B0K032 | 1-173 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1308687 | AgrOrtholog |
BioCyc Gene | G2FUF-33047 | BioCyc |
Ensembl Genes | ENSRNOG00000007628 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000010224.7 | UniProtKB/TrEMBL |
ENSRNOT00000096141.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.90.190.10 | UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:9092581 | IMAGE-MGC_LOAD |
InterPro | Dual-sp/Tyr_phosphatase | UniProtKB/TrEMBL |
Prot-tyrosine_phosphatase-like | UniProtKB/TrEMBL | |
PTPase_domain | UniProtKB/TrEMBL | |
Tyr_Pase_cat | UniProtKB/TrEMBL | |
TYR_PHOSPHATASE_DUAL_dom | UniProtKB/TrEMBL | |
KEGG Report | rno:362930 | UniProtKB/TrEMBL |
MGC_CLONE | MGC:188757 | IMAGE-MGC_LOAD |
NCBI Gene | 362930 | ENTREZGENE |
PANTHER | PROTEIN TYROSINE PHOSPHATASE TYPE IVA 3 | UniProtKB/TrEMBL |
TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE | UniProtKB/TrEMBL | |
Pfam | Y_phosphatase | UniProtKB/TrEMBL |
PhenoGen | Ptp4a3 | PhenoGen |
PROSITE | TYR_PHOSPHATASE_2 | UniProtKB/TrEMBL |
TYR_PHOSPHATASE_DUAL | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000007628 | RatGTEx |
SMART | PTPc_motif | UniProtKB/TrEMBL |
Superfamily-SCOP | SSF52799 | UniProtKB/TrEMBL |
UniProt | A0A8I5Y855 | ENTREZGENE, UniProtKB/TrEMBL |
B0K032 | ENTREZGENE, UniProtKB/TrEMBL | |
F7EWD1 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2019-04-03 | Ptp4a3 | protein tyrosine phosphatase 4A3 | Ptp4a3 | protein tyrosine phosphatase type IVA, member 3 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2011-02-22 | Ptp4a3 | protein tyrosine phosphatase type IVA, member 3 | Ptp4a3 | protein tyrosine phosphatase 4a3 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | Ptp4a3 | protein tyrosine phosphatase 4a3 | Ptp4a3_predicted | protein tyrosine phosphatase 4a3 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Ptp4a3_predicted | protein tyrosine phosphatase 4a3 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |