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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of ABL1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ABL1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ABL1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of ACOX2 mRNA |
CTD |
PMID:15120970 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Adam10 |
ADAM metallopeptidase domain 10 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ADAM10 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of AGT mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of AGT mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA |
CTD |
PMID:19840844 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions increases localization |
ISO |
benzamide inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein]; phenanthridone inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein] |
CTD |
PMID:15589979 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of AKT1 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of AKT1 mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
decreases secretion |
EXP |
Methylnitronitrosoguanidine results in decreased secretion of ALB protein |
CTD |
PMID:15772367 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of ALDH1A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of ALDH1A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ALPL mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Ambp |
alpha-1-microglobulin/bikunin precursor |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of AMBP mRNA |
CTD |
PMID:12773770 |
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NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
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G |
Anxa5 |
annexin A5 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ANXA5 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
affects response to substance multiple interactions decreases expression |
ISO |
APAF1 protein affects the susceptibility to Methylnitronitrosoguanidine Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of APAF1 protein] |
CTD |
PMID:16019050 PMID:20434464 |
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NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apc |
APC regulator of WNT signaling pathway |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of APC mRNA |
CTD |
PMID:12634122 |
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NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of APP mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of APP mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of APP mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Araf |
A-Raf proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ARAF mRNA |
CTD |
PMID:12634122 |
|
NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073
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G |
Atm |
ATM serine/threonine kinase |
increases response to substance |
ISO |
ATM gene mutant form results in increased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:15010311 |
|
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atp1b3 |
ATPase Na+/K+ transporting subunit beta 3 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of ATP1B3 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
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G |
Atr |
ATR serine/threonine kinase |
multiple interactions |
ISO |
ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein] |
CTD |
PMID:26921499 |
|
NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
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G |
Axl |
Axl receptor tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of AXL mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
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G |
Bad |
BCL2-associated agonist of cell death |
decreases expression multiple interactions decreases phosphorylation |
ISO |
Methylnitronitrosoguanidine results in decreased expression of BAD mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAD mRNA] N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of BAD protein] |
CTD |
PMID:17828454 PMID:20434464 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag1 |
BAG cochaperone 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of BAG1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
ISO |
BAK1 protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] |
CTD |
PMID:18376143 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions decreases expression |
EXP ISO |
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BAX protein; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein] BAX protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein] Methylnitronitrosoguanidine results in decreased expression of BAX mRNA; Methylnitronitrosoguanidine results in decreased expression of BAX protein |
CTD |
PMID:16030430 PMID:18376143 PMID:20434464 PMID:35103375 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcat2 |
branched chain amino acid transaminase 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BCAT2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions increases expression |
ISO EXP |
Methylnitronitrosoguanidine results in decreased expression of BCL2 protein [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein] Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA; Methylnitronitrosoguanidine results in increased expression of BCL2 protein |
CTD |
PMID:16019050 PMID:16030430 PMID:20434464 PMID:35103375 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions increases expression |
ISO |
BCL2L1 protein results in decreased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA] |
CTD |
PMID:18376143 PMID:20434464 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
multiple interactions |
EXP |
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein] |
CTD |
PMID:16030430 |
|
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Bdnf |
brain-derived neurotrophic factor |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of BDNF mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bgn |
biglycan |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of BGN mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of BGN mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BGN mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions decreases expression |
ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BID mRNA] |
CTD |
PMID:20434464 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of BIRC2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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G |
Blvrb |
biliverdin reductase B |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BLVRB mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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G |
Bmp4 |
bone morphogenetic protein 4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of BMP4 mRNA |
CTD |
PMID:12773770 |
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NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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G |
Brca1 |
BRCA1, DNA repair associated |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of BRCA1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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G |
Brca2 |
BRCA2, DNA repair associated |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of BRCA2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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G |
Bsg |
basigin (Ok blood group) |
multiple interactions increases expression |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BSG mRNA] |
CTD |
PMID:35103375 |
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NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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G |
Btg2 |
BTG anti-proliferation factor 2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of BTG2 protein |
CTD |
PMID:24821435 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
C1qb |
complement C1q B chain |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of C1QB mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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G |
C1s |
complement C1s |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of C1S mRNA |
CTD |
PMID:15120970 |
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NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CALM1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CALM1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CALM1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Casp3 |
caspase 3 |
increases activity multiple interactions decreases expression |
ISO EXP |
Methylnitronitrosoguanidine results in increased activity of CASP3 protein [Methylnitronitrosoguanidine co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased activity of CASP3 protein; [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride promotes the reaction [Methylnitronitrosoguanidine results in increased activity of CASP3 protein] Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA; Methylnitronitrosoguanidine results in decreased expression of CASP3 protein |
CTD |
PMID:15589979 PMID:16019050 PMID:16030430 PMID:17428624 PMID:20434464 PMID:24476502 PMID:35103375 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CASP4 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp8 |
caspase 8 |
multiple interactions |
EXP |
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein; [S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] |
CTD |
PMID:16030430 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases activity multiple interactions decreases expression |
ISO EXP |
Methylnitronitrosoguanidine results in increased activity of CASP9 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein] corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein] |
CTD |
PMID:15589979 PMID:16019050 PMID:20434464 PMID:35103375 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions decreases activity |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased activity of CAT protein] |
CTD |
PMID:35103375 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cbx5 |
chromobox 5 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CBX5 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
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G |
Ccna1 |
cyclin A1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CCNA1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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G |
Ccnb1 |
cyclin B1 |
multiple interactions increases expression decreases expression |
EXP ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCNB1 mRNA] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCNB1 mRNA Methylnitronitrosoguanidine results in decreased expression of CCNB1 mRNA |
CTD |
PMID:11516527 PMID:12135628 PMID:19851710 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
multiple interactions increases expression |
EXP ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA] Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA; Methylnitronitrosoguanidine results in increased expression of CCND1 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCND1 protein |
CTD |
PMID:12135628 PMID:19851710 PMID:21628965 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccng1 |
cyclin G1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CCNG1 mRNA |
CTD |
PMID:11516527 |
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NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Ccnh |
cyclin H |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CCNH mRNA |
CTD |
PMID:12634122 |
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NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819
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G |
Cct2 |
chaperonin containing TCP1 subunit 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCT2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
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G |
Cd59b |
CD59b molecule |
increases mutagenesis |
ISO |
Methylnitronitrosoguanidine results in increased mutagenesis of CD59 protein |
CTD |
PMID:17045307 |
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NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
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G |
Cd9 |
CD9 molecule |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CD9 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CD9 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD9 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
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G |
Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] |
CTD |
PMID:28428697 |
|
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh8 |
cadherin 8 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CDH8 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669
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G |
Cdk4 |
cyclin-dependent kinase 4 |
increases expression multiple interactions |
EXP ISO |
Methylnitronitrosoguanidine results in increased expression of CDK4 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CDK4 protein |
CTD |
PMID:12135628 PMID:21628965 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdk5 |
cyclin-dependent kinase 5 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CDK5 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
decreases expression multiple interactions |
ISO EXP |
Methylnitronitrosoguanidine results in decreased expression of CDKN1A mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein] |
CTD |
PMID:12634122 PMID:19851710 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CDKN1B mRNA Methylnitronitrosoguanidine results in increased expression of CDKN1B protein Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDKN1B protein]; Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1B mRNA] |
CTD |
PMID:11516527 PMID:12135628 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cep43 |
centrosomal protein 43 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CEP43 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:52,533,418...52,564,025
Ensembl chr 1:52,533,428...52,563,923
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G |
Chek1 |
checkpoint kinase 1 |
multiple interactions |
ISO |
CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein] |
CTD |
PMID:26921499 |
|
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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G |
Chek2 |
checkpoint kinase 2 |
multiple interactions |
ISO |
CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein] |
CTD |
PMID:26921499 |
|
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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G |
Ckb |
creatine kinase B |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CKB mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Clta |
clathrin, light chain A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CLTA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CLTA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CLTA mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL1A2 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col6a1 |
collagen type VI alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL6A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL6A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL6A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL8A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL8A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL8A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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G |
Cox6a1 |
cytochrome c oxidase subunit 6A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX6A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
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G |
Cox8a |
cytochrome c oxidase subunit 8A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX8A mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:204,402,118...204,404,439
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases expression |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsb |
cathepsin B |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of CTSB mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of CTSB mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CTSB mRNA |
CTD |
PMID:19840844 |
|
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsl |
cathepsin L |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CTSL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CTSL mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CTSL mRNA |
CTD |
PMID:19840844 |
|
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CXCL12 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CXCR4 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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G |
Cyb561d2 |
cytochrome b561 family, member D2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CYB561D2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:108,213,201...108,215,778
Ensembl chr 8:108,213,205...108,215,759
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G |
Cycs |
cytochrome c, somatic |
multiple interactions decreases expression |
ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS protein] Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA; Methylnitronitrosoguanidine results in decreased expression of CYCS protein |
CTD |
PMID:20434464 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Dab2 |
DAB adaptor protein 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of DAB2 mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
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G |
Dcn |
decorin |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of DCN mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
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G |
Deaf1 |
DEAF1 transcription factor |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of DEAF1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
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G |
Dek |
DEK proto-oncogene |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of DEK mRNA |
CTD |
PMID:12634122 |
|
NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
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G |
Dlg1 |
discs large MAGUK scaffold protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of DLG1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of DLG1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DLG1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
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G |
Dstn |
destrin, actin depolymerizing factor |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of DSTN mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
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G |
Dut |
deoxyuridine triphosphatase |
affects localization increases secretion |
ISO |
Methylnitronitrosoguanidine affects the localization of DUT protein Methylnitronitrosoguanidine results in increased secretion of DUT protein |
CTD |
PMID:21658424 |
|
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
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G |
E2f1 |
E2F transcription factor 1 |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of E2F1 protein ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; E2F1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
|
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
E2f3 |
E2F transcription factor 3 |
multiple interactions |
ISO |
[[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; [Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHIR-124 inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; E2F3 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]] |
CTD |
PMID:26921499 |
|
NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
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G |
Egf |
epidermal growth factor |
affects activity multiple interactions |
ISO |
Methylnitronitrosoguanidine affects the activity of EGF protein Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased activity of HRAS protein]; Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] |
CTD |
PMID:15708576 |
|
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
affects localization multiple interactions |
ISO |
Methylnitronitrosoguanidine affects the localization of EGFR protein Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] |
CTD |
PMID:15708576 |
|
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EGR1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
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G |
Eif3e |
eukaryotic translation initiation factor 3 subunit E |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of EIF3E mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of EIF5 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EIF5A mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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G |
Elk3 |
ETS transcription factor ELK3 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ELK3 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084
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G |
Emp1 |
epithelial membrane protein 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of EMP1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of ENPP2 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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G |
Epcam |
epithelial cell adhesion molecule |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of EPCAM mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
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G |
Epha1 |
Eph receptor A1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of EPHA1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
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G |
Ephb3 |
Eph receptor B3 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of EPHB3 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370
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G |
Eps8 |
EGFR pathway substrate 8, signaling adaptor |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EPS8 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ERBB2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ERBB4 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
Esr2 |
estrogen receptor 2 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of ESR2 mRNA; Methylnitronitrosoguanidine results in increased expression of ESR2 protein |
CTD |
PMID:21628965 PMID:22330348 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ETS1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
Faslg |
Fas ligand |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of FASLG protein |
CTD |
PMID:24821435 |
|
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of FASN mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fau |
FAU ubiquitin like and ribosomal protein S30 fusion |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of FAU mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of FAU mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742
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G |
Fcer1a |
Fc epsilon receptor Ia |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of FCER1A mRNA |
CTD |
PMID:15120970 |
|
NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
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G |
Fcgr2a |
Fc gamma receptor 2A |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of FCGR3 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
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G |
Fcgrt |
Fc gamma receptor and transporter |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of FCGRT mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084
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G |
Fes |
FES proto-oncogene, tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of FES mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934
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G |
Fgf10 |
fibroblast growth factor 10 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of FGF10 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of FLT1 mRNA] |
CTD |
PMID:20434464 |
|
NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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|
G |
Folr1 |
folate receptor alpha |
increases methylation |
ISO |
Methylnitronitrosoguanidine results in increased methylation of FOLR1 promoter |
CTD |
PMID:29644877 |
|
NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
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|
G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
decreases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in decreased expression of FOSL1 mRNA Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:12634122 PMID:26921499 |
|
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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|
G |
Fst |
follistatin |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of FST mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
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|
G |
Fstl1 |
follistatin-like 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of FSTL1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of FSTL1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FSTL1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of FYN mRNA |
CTD |
PMID:12634122 |
|
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
decreases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA] |
CTD |
PMID:19851710 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gcgr |
glucagon receptor |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of GCGR mRNA |
CTD |
PMID:15120970 |
|
NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of GDF15 mRNA |
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJA1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of GJB2 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
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G |
Gli1 |
GLI family zinc finger 1 |
increases expression |
EXP |
MNNG increases expression of Gli1 mRNA in rat stomach |
RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
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G |
Gpc4 |
glypican 4 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GPC4 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GPC4 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GPC4 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr X:131,644,711...131,755,349
Ensembl chr X:131,644,704...131,755,284
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G |
Gss |
glutathione synthetase |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of GSS mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
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G |
Gstm2 |
glutathione S-transferase mu 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GSTM2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GSTM2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GSTM2 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gsto1 |
glutathione S-transferase omega 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of GSTO1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTO1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTO1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of GSTP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTP1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gtf2i |
general transcription factor II I |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [GTF2I protein binds to RRM2 promoter] |
CTD |
PMID:26921499 |
|
NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243
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G |
H2ax |
H2A.X variant histone |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; E2F3 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; RRM2 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form] |
CTD |
PMID:26921499 PMID:27233451 |
|
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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G |
H4c14 |
H4 clustered histone 14 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of H4C2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048
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G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of HBA1 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of HIF1A mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HIF1A mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmgb1 |
high mobility group box 1 |
increases expression multiple interactions |
ISO EXP |
Methylnitronitrosoguanidine results in increased expression of HMGB1 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HMGB1 mRNA] |
CTD |
PMID:12634122 PMID:35103375 |
|
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmgb2 |
high mobility group box 2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of HMGB2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of HPGD mRNA |
CTD |
PMID:15120970 |
|
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HPRT1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of HPRT1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased activity of HRAS protein] |
CTD |
PMID:15708576 |
|
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AB1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of HSP90B1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of HSPA1A mRNA |
CTD |
PMID:15120970 |
|
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSPD1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Icam1 |
intercellular adhesion molecule 1 |
decreases response to substance increases expression multiple interactions |
ISO |
ICAM1 protein results in decreased susceptibility to Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of ICAM1 mRNA; Methylnitronitrosoguanidine results in increased expression of ICAM1 protein prolinedithiocarbamate inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of ICAM1 protein] |
CTD |
PMID:22001597 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id1 |
inhibitor of DNA binding 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of ID1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Ier3 |
immediate early response 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of IER3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IER3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IER3 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ifitm1 |
interferon induced transmembrane protein 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of IFITM1 mRNA |
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of IFRD1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
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G |
Igkc |
immunoglobulin kappa constant |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of IGKC mRNA |
CTD |
PMID:15120970 |
|
|
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G |
Igsf6 |
immunoglobulin superfamily, member 6 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of IGSF6 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 1:175,610,167...175,620,662
Ensembl chr 1:175,610,167...175,620,722
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IKBKB protein] |
CTD |
PMID:19851710 |
|
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of IRAK1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IRAK1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IRAK1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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G |
Itgb4 |
integrin subunit beta 4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of ITGB4 mRNA |
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
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G |
Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of JMJD6 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
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G |
Jpt1 |
Jupiter microtubule associated homolog 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of JPT1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
|
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Kctd12 |
potassium channel tetramerization domain containing 12 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of KCTD12 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282
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G |
Kdm8 |
lysine demethylase 8 |
multiple interactions |
ISO |
Methylnitronitrosoguanidine inhibits the reaction [TP53 protein binds to KDM8 protein] |
CTD |
PMID:26025680 |
|
NCBI chr 1:180,013,969...180,028,829
Ensembl chr 1:180,020,656...180,028,841
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of KIT mRNA |
CTD |
PMID:12634122 |
|
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Kitlg |
KIT ligand |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of KITLG mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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|
G |
Klf10 |
KLF transcription factor 10 |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of KLF10 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Kras |
KRAS proto-oncogene, GTPase |
multiple interactions increases expression |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 4:178,185,418...178,218,484
|
|
G |
Krt17 |
keratin 17 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of KRT17 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
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|
G |
Ldha |
lactate dehydrogenase A |
multiple interactions increases expression |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of LDHA mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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|
G |
Lgals3 |
galectin 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LGALS3 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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G |
Lgals8 |
galectin 8 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of LGALS8 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
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|
G |
Lig1 |
DNA ligase 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of LIG1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
|
|
G |
Lipa |
lipase A, lysosomal acid type |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of LIP1 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633
|
|
G |
Lox |
lysyl oxidase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LOX mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LOX mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LOX mRNA |
CTD |
PMID:19840844 |
|
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
|
|
G |
Lpl |
lipoprotein lipase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LPL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LPL mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LPL mRNA |
CTD |
PMID:19840844 |
|
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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|
G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
|
|
G |
Map3k12 |
mitogen activated protein kinase kinase kinase 12 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MAP3K12 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MAP3K12 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAP3K12 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases phosphorylation |
ISO |
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK1 protein]] |
CTD |
PMID:17828454 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
increases phosphorylation |
ISO |
Methylnitronitrosoguanidine results in increased phosphorylation of MAPK14 protein |
CTD |
PMID:22001597 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases phosphorylation |
ISO |
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK3 protein]] |
CTD |
PMID:17828454 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk4 |
mitogen-activated protein kinase 4 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MAPK4 mRNA |
CTD |
PMID:12634122 |
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NCBI chr18:67,512,805...67,661,271
Ensembl chr18:67,512,807...67,661,842
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
Methylnitronitrosoguanidine results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:22001597 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MAPK9 mRNA |
CTD |
PMID:12634122 |
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NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of MARCKS mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MARCKS mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARCKS mRNA |
CTD |
PMID:19840844 |
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NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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G |
Max |
MYC associated factor X |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MAX mRNA |
CTD |
PMID:12634122 |
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NCBI chr 6:95,636,859...95,662,204
Ensembl chr 6:95,636,858...95,662,137
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G |
Mcam |
melanoma cell adhesion molecule |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MCAM mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
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G |
Mcm2 |
minichromosome maintenance complex component 2 |
decreases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MCM2 mRNA [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MCM2 mRNA |
CTD |
PMID:12634122 PMID:19840844 |
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NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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G |
Mcm4 |
minichromosome maintenance complex component 4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MCM4 mRNA |
CTD |
PMID:12634122 |
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NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
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G |
Mcm6 |
minichromosome maintenance complex component 6 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MCM6 mRNA |
CTD |
PMID:19840844 |
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NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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G |
Mdm2 |
MDM2 proto-oncogene |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of MDM2 mRNA Methylnitronitrosoguanidine results in increased expression of MDM2 protein Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein] |
CTD |
PMID:12135628 PMID:12634122 |
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NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Mecom |
MDS1 and EVI1 complex locus |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MECOM mRNA |
CTD |
PMID:12634122 |
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NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
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G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MET mRNA |
CTD |
PMID:12634122 |
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NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
decreases response to substance |
ISO |
MGMT protein results in decreased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:1727384 PMID:15010311 PMID:16043385 |
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NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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G |
Mgst2 |
microsomal glutathione S-transferase 2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MGST2 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
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G |
Mgst3 |
microsomal glutathione S-transferase 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MGST3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
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G |
Mir21 |
microRNA 21 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MIR21 mRNA |
CTD |
PMID:24821435 |
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NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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G |
Mlh1 |
mutL homolog 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MLH1 protein |
CTD |
PMID:17671175 |
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NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
EXP ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP2 mRNA]; Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MMP2 mRNA |
CTD |
PMID:19840844 PMID:20434464 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP9 mRNA]; Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein |
CTD |
PMID:20434464 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpg |
N-methylpurine-DNA glycosylase |
increases response to substance |
ISO |
MPG protein results in increased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:15299078 |
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NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
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G |
Mpp1 |
MAGUK p55 scaffold protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of MPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MPP1 mRNA |
CTD |
PMID:19840844 |
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G |
Msh2 |
mutS homolog 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MSH2 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
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G |
Mst1 |
macrophage stimulating 1 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of MST1 mRNA |
CTD |
PMID:15120970 |
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NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
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G |
Mt1 |
metallothionein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MT1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MT1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MT1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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G |
Mthfr |
methylenetetrahydrofolate reductase |
increases methylation |
ISO |
Methylnitronitrosoguanidine results in increased methylation of MTHFR promoter |
CTD |
PMID:29644877 |
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NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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G |
Mutyh |
mutY DNA glycosylase |
multiple interactions |
ISO |
MUTYH protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PARP1 protein] |
CTD |
PMID:26954031 |
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NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146
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G |
Mybl1 |
MYB proto-oncogene like 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MYBL1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of MYC protein Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MYC protein] |
CTD |
PMID:12135628 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Myl2 |
myosin light chain 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MYL2 mRNA |
CTD |
PMID:12634122 |
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NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983
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G |
Myl9 |
myosin light chain 9 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MYL9 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
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G |
Mylk |
myosin light chain kinase |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MYLK mRNA |
CTD |
PMID:12634122 |
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NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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G |
Nbl1 |
NBL1, DAN family BMP antagonist |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of NBL1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein] Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA; Methylnitronitrosoguanidine results in increased expression of NFKB1 protein |
CTD |
PMID:19851710 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases expression increases expression |
EXP ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKBIA protein modified form] Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA; Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased degradation of NFKBIA protein |
CTD |
PMID:19851710 PMID:22001597 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfya |
nuclear transcription factor Y subunit alpha |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
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NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898
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G |
Nfyb |
nuclear transcription factor Y subunit beta |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [NFYB protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein] |
CTD |
PMID:26921499 |
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NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565
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G |
Nfyc |
nuclear transcription factor Y subunit gamma |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [NFYC protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
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NCBI chr 5:134,336,802...134,405,372
Ensembl chr 5:134,336,808...134,405,377
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G |
Nrp1 |
neuropilin 1 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of NRP1 mRNA |
CTD |
PMID:15120970 |
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NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
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G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of ODC1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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G |
Pa2g4 |
proliferation-associated 2G4 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PA2G4 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
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G |
Parg |
poly (ADP-ribose) glycohydrolase |
multiple interactions affects response to substance |
ISO |
[Hydrolyzable Tannins results in decreased activity of PARG protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; [nobotanin B results in decreased activity of PARG protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; benzamide inhibits the reaction [PARG affects the susceptibility to Methylnitronitrosoguanidine] |
CTD |
PMID:11593040 PMID:15591342 |
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NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases activity affects cleavage increases response to substance increases expression |
ISO |
[benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; [Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD; benzamide inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; Eugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein]; Hydrolyzable Tannins inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; MUTYH protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PARP1 protein] PARP1 protein results in increased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:11593040 PMID:20434464 PMID:22001597 PMID:26954031 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pcbp2 |
poly(rC) binding protein 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PCBP2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCBP2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCBP2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863
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G |
Pcdh7 |
protocadherin 7 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of PCDH7 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051 Ensembl chr14:52,475,610...52,902,051
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G |
Pcna |
proliferating cell nuclear antigen |
decreases expression multiple interactions increases expression |
ISO EXP |
Methylnitronitrosoguanidine results in decreased expression of PCNA mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PCNA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCNA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PCNA mRNA]; Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein] Methylnitronitrosoguanidine results in increased expression of PCNA mRNA; Methylnitronitrosoguanidine results in increased expression of PCNA protein |
CTD |
PMID:11516527 PMID:12135628 PMID:12634122 PMID:19840844 PMID:19851710 PMID:22330348 PMID:28428697 More...
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pdgfb |
platelet derived growth factor subunit B |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PDGFB mRNA |
CTD |
PMID:12634122 |
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NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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G |
Pdgfra |
platelet derived growth factor receptor alpha |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PDGFRA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PDGFRA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PDGFRA mRNA |
CTD |
PMID:19840844 |
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NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
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G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PDIA3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PDIA3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDIA3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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G |
Pea15 |
proliferation and apoptosis adaptor protein 15 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PEA15 mRNA |
CTD |
PMID:12634122 |
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NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
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G |
Pgk1 |
phosphoglycerate kinase 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PGK1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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G |
Pgr |
progesterone receptor |
decreases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in decreased expression of PGR protein geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein] |
CTD |
PMID:28428697 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Pik3cg |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of PIK3CG mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3CG mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
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G |
Plxna3 |
plexin A3 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PLXNA3 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr X:152,115,699...152,131,608
Ensembl chr X:152,115,819...152,131,603
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G |
Podxl |
podocalyxin-like |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PODXL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PODXL mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
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G |
Postn |
periostin |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of POSTN mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
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G |
Ppp2r2a |
protein phosphatase 2, regulatory subunit B, alpha |
decreases response to substance |
ISO |
PPP2R2A protein results in decreased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:25772433 |
|
NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924
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G |
Ppp2r5c |
protein phosphatase 2, regulatory subunit B', gamma |
increases response to substance |
ISO |
PPP2R5C protein results in increased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:25772433 |
|
NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
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G |
Ppp2r5e |
protein phosphatase 2 regulatory subunit B', epsilon |
decreases response to substance |
ISO |
PPP2R5E protein results in decreased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:25772433 |
|
NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872
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G |
Prkd1 |
protein kinase D1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PRKD1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
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G |
Pten |
phosphatase and tensin homolog |
decreases response to substance decreases expression multiple interactions |
ISO EXP |
PTEN protein results in decreased susceptibility to Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in decreased expression of PTEN protein geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein] |
CTD |
PMID:20530668 PMID:28428697 |
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NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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G |
Ptn |
pleiotrophin |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PTN mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PTN mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTN mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
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G |
Ptp4a1 |
protein tyrosine phosphatase 4A1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PTP4A1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
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G |
Ptpra |
protein tyrosine phosphatase, receptor type, A |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of PTPRA mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:117,650,146...117,759,744
Ensembl chr 3:117,650,183...117,759,728
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G |
Ptprg |
protein tyrosine phosphatase, receptor type, G |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of PTPRG mRNA |
CTD |
PMID:12634122 |
|
NCBI chr15:12,871,706...13,552,186
Ensembl chr15:12,871,721...13,554,094
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G |
Ptprs |
protein tyrosine phosphatase, receptor type, S |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of PTPRS mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PTTG1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PTTG1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTTG1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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G |
Pura |
purine rich element binding protein A |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [PURA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [PURA protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
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NCBI chr18:27,885,071...27,905,509
Ensembl chr18:27,884,556...27,905,513
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G |
Racgap1 |
Rac GTPase-activating protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RACGAP1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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G |
Rad21 |
RAD21 cohesin complex component |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RAD21 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
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G |
Rad23a |
RAD23 homolog A, nucleotide excision repair protein |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of RAD23A mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695
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G |
Rbbp5 |
RB binding protein 5, histone lysine methyltransferase complex subunit |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of RBBP5 mRNA |
CTD |
PMID:12634122 |
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NCBI chr13:43,912,254...43,939,107
Ensembl chr13:43,912,254...43,939,107
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G |
Rbm6 |
RNA binding motif protein 6 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of RBM6 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 8:108,452,687...108,552,783
Ensembl chr 8:108,452,687...108,552,771
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G |
Reck |
reversion-inducing-cysteine-rich protein with kazal motifs |
multiple interactions decreases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK protein] Methylnitronitrosoguanidine results in decreased expression of RECK mRNA; Methylnitronitrosoguanidine results in decreased expression of RECK protein |
CTD |
PMID:20434464 |
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NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein] Methylnitronitrosoguanidine results in increased expression of RELA mRNA; Methylnitronitrosoguanidine results in increased expression of RELA protein |
CTD |
PMID:19851710 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Reln |
reelin |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of RELN mRNA |
CTD |
PMID:15120970 |
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NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
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G |
Rgs18 |
regulator of G-protein signaling 18 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of RGS18 mRNA |
CTD |
PMID:15120970 |
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NCBI chr13:56,493,134...56,516,045
Ensembl chr13:56,494,010...56,516,098
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G |
Ros1 |
ROS proto-oncogene 1 , receptor tyrosine kinase |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of ROS1 mRNA |
CTD |
PMID:15120970 |
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NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865
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G |
Rpl7 |
ribosomal protein L7 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of RPL7 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPL7 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPL7 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:3,217,184...3,220,192
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G |
Rps11 |
ribosomal protein S11 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874
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G |
Rps20 |
ribosomal protein S20 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of RPS20 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPS20 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS20 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475 Ensembl chr 9:16,819,304...16,820,475 Ensembl chr 3:16,819,304...16,820,475
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G |
Rpsa |
ribosomal protein SA |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of RPSA mRNA |
CTD |
PMID:12773770 |
|
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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G |
Rrm2 |
ribonucleotide reductase regulatory subunit M2 |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; [Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; CHIR-124 inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [DP1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [DP1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [GTF2I protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [IFI16 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [IFI16 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [PURA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [PURA protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine results in increased expression of and affects the localization of RRM2 protein; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; RRM2 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form] |
CTD |
PMID:26921499 |
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NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
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G |
Rrm2b |
ribonucleotide reductase regulatory TP53 inducible subunit M2B |
increases expression affects expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA Methylnitronitrosoguanidine affects the expression of RRM2B mRNA ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; E2F1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine results in increased expression of and affects the localization of RRM2B protein; TP53 protein mutant form inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein] |
CTD |
PMID:21704725 PMID:26921499 |
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NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
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G |
RT1-Db1 |
RT1 class II, locus Db1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of HLA-DRB1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
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G |
Ruvbl1 |
RuvB-like AAA ATPase 1 |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
|
NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384
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G |
Sec61g |
Sec61 translocon subunit gamma |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA |
CTD |
PMID:19840844 |
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NCBI chr14:90,899,766...90,906,143
Ensembl chr14:90,899,768...90,906,162
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G |
Selenop |
selenoprotein P |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of SELENOP mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of SELENOP mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SELENOP mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
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G |
Serpine1 |
serpin family E member 1 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of SERPINE1 mRNA |
CTD |
PMID:15120970 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Serping1 |
serpin family G member 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of SERPING1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
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G |
Slc16a3 |
solute carrier family 16 member 3 |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of SLC16A3 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SLC16A3 mRNA] |
CTD |
PMID:35103375 |
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NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562
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G |
Smad2 |
SMAD family member 2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of SMAD2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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G |
Smo |
smoothened, frizzled class receptor |
increases expression |
EXP |
MNNG increases expression of Smo mRNA in rat stomach |
RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
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G |
Snora62 |
small nucleolar RNA, H/ACA box 62 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of SNORA62 mRNA |
CTD |
PMID:12773770 |
|
NCBI chr 8:119,853,958...119,854,106
Ensembl chr 8:119,853,958...119,854,106
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G |
Snrpn |
small nuclear ribonucleoprotein polypeptide N |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of SNRPN mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:111,101,327...111,123,400
Ensembl chr 1:111,101,329...111,123,634
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G |
Sparc |
secreted protein acidic and cysteine rich |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of SPARC mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Spink1 |
serine peptidase inhibitor, Kazal type 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of SPINK1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
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G |
Spint2 |
serine peptidase inhibitor, Kunitz type, 2 |
decreases expression increases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of SPINT2 mRNA Methylnitronitrosoguanidine results in increased expression of SPINT2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:84,558,159...84,580,616
Ensembl chr 1:84,558,166...84,580,616
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SPP1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Sqle |
squalene epoxidase |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of SQLE mRNA [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SQLE mRNA |
CTD |
PMID:12634122 PMID:19840844 |
|
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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G |
Srsf7 |
serine and arginine rich splicing factor 7 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of SRSF7 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
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G |
Stk39 |
serine threonine kinase 39 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of STK39 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060
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G |
Sufu |
SUFU negative regulator of hedgehog signaling |
decreases expression |
EXP |
MNNG decreases expression of Sufu mRNA in rat stomach |
RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
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G |
Sumo2 |
small ubiquitin-like modifier 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SUMO2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SUMO2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SUMO2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513
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G |
Syn1 |
synapsin I |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SYN1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SYN1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SYN1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396
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G |
Tbrg4 |
transforming growth factor beta regulator 4 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TBRG4 mRNA |
CTD |
PMID:12634122 |
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NCBI chr14:81,481,977...81,490,781
Ensembl chr14:81,481,981...81,490,756
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA] |
CTD |
PMID:28428697 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Thbs1 |
thrombospondin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of THBS1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
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G |
Thbs2 |
thrombospondin 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
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G |
Tiam1 |
TIAM Rac1 associated GEF 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TIAM1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
decreases expression multiple interactions |
EXP ISO |
Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA; Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of TIMP2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TIMP2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TIMP2 mRNA |
CTD |
PMID:19840844 PMID:20434464 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Tlr4 |
toll-like receptor 4 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of TLR4 mRNA |
CTD |
PMID:15120970 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tmsb4x |
thymosin beta 4, X-linked |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TMSB4X mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:27,144,666...27,146,667
Ensembl chr X:27,128,610...27,146,667
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G |
Tnc |
tenascin C |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TNC mRNA |
CTD |
PMID:12634122 |
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NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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G |
Tnfrsf25 |
TNF receptor superfamily member 25 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TNFRSF25 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
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G |
Top2a |
DNA topoisomerase II alpha |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TOP2A mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TOP2A mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TOP2A mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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G |
Tp53 |
tumor protein p53 |
increases expression decreases response to substance increases response to substance increases acetylation multiple interactions decreases expression |
ISO EXP |
Methylnitronitrosoguanidine results in increased expression of TP53 mRNA; Methylnitronitrosoguanidine results in increased expression of TP53 protein TP53 protein mutant form results in decreased susceptibility to Methylnitronitrosoguanidine TP53 protein results in increased susceptibility to Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased acetylation of TP53 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]; resveratrol inhibits the reaction [Methylnitronitrosoguanidine results in increased acetylation of TP53 protein] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TRP53 mRNA; Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TRP53 protein] ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; Methylnitronitrosoguanidine inhibits the reaction [TP53 protein binds to KDM8 protein]; TP53 protein mutant form inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein] |
CTD |
PMID:9667752 PMID:11516527 PMID:12135628 PMID:12634122 PMID:15589979 PMID:17147953 PMID:19851710 PMID:26025680 PMID:26921499 More...
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tram1 |
translocation associated membrane protein 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TRAM1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 5:5,642,579...5,667,666
Ensembl chr 5:5,642,546...5,686,971
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G |
Tsc22d1 |
TSC22 domain family, member 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of TSC22D1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
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G |
Ttc3 |
tetratricopeptide repeat domain 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of TTC3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TTC3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TTC3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975
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G |
Txn1 |
thioredoxin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TXN1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TXN1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TXN1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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G |
Ubc |
ubiquitin C |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of UBC mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of UBC mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of UBC mRNA |
CTD |
PMID:19840844 |
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NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of UCHL1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
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G |
Ucp2 |
uncoupling protein 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of UCP2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Vim |
vimentin |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of VIM mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Wars1 |
tryptophanyl-tRNA synthetase 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of WARS1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
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G |
Wnt2 |
Wnt family member 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of WNT2 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
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G |
Yy1 |
YY1 transcription factor |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [YY1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
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NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
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