Gene: Adam10 (ADAM metallopeptidase domain 10) Rattus norvegicus
Symbol: Adam10
Name: ADAM metallopeptidase domain 10
Description: ENCODES a protein that exhibits metalloendopeptidase activity; metallopeptidase activity; endopeptidase activity (ortholog); INVOLVED IN amyloid-beta formation; constitutive protein ectodomain proteolysis (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; interleukin-6 signaling pathway; Notch signaling pathway; ASSOCIATED WITH Aortic Aneurysm, Thoracic; Status Epilepticus; Alzheimer Disease 18 (ortholog); FOUND IN cell surface; dendritic spine; membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrolein
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: a disintegrin and metallopeptidase domain 10; a disintegrin and metalloprotease domain (ADAM) 10; a disintegrin and metalloprotease domain 10; ADAM 10; disintegrin and metalloproteinase domain-containing protein 10; kuzbanian; kuzbanian protein homolog; LOC501019; MADM; mammalian disintegrin-metalloprotease; RGD1566370; RGD1566370
Homo sapiens (human) : ADAM10 (ADAM metallopeptidase domain 10)  HGNC  AGR
Mus musculus (house mouse) : Adam10 (a disintegrin and metallopeptidase domain 10)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Adam10 (ADAM metallopeptidase domain 10)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAM10 (ADAM metallopeptidase domain 10)
Canis lupus familiaris (dog) : ADAM10 (ADAM metallopeptidase domain 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adam10 (ADAM metallopeptidase domain 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0877,107,355 - 77,237,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0875,842,118 - 75,974,564 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4875,200,657 - 75,289,572 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1875,307,687 - 75,310,191 (+)NCBI
Celera870,259,195 - 70,383,316 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Adam10
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2032
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE