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Fc(epsilon)RI and FcgammaRIII/CD16 differentially regulate atopic dermatitis in mice. |
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2. |
Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. |
Aitman TJ, etal., Nature. 2006 Feb 16;439(7078):851-5.
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3. |
Expression of Fc gamma and complement receptors in monocytes of X-linked agammaglobulinaemia and common variable immunodeficiency patients. |
Amoras AL, etal., Clin Exp Immunol. 2007 Dec;150(3):422-8. Epub 2007 Sep 27.
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4. |
FcgammaRIII-expressing macrophages are essential for development of collagen-induced arthritis. |
Andren M, etal., Scand J Immunol. 2006 Apr;63(4):282-9.
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5. |
Fc gamma RIIA H/R 131 polymorphism, subclass-specific IgG anti-heparin/platelet factor 4 antibodies and clinical course in patients with heparin-induced thrombocytopenia and thrombosis. |
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A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. |
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7. |
Multiplex family-based study in systemic lupus erythematosus: association between the R620W polymorphism of PTPN22 and the FcgammaRIIa (CD32A) R131 allele. |
Balada E, etal., Tissue Antigens. 2006 Nov;68(5):432-8.
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8. |
Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. |
Baudino L, etal., J Immunol. 2008 Feb 1;180(3):1948-53.
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9. |
Fc gamma RIIa polymorphism: a susceptibility factor for immune complex-mediated lupus nephritis in Brazilian patients. |
Bazilio AP, etal., Nephrol Dial Transplant. 2004 Jun;19(6):1427-31. Epub 2004 Mar 5.
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10. |
Specificity and class distribution of Fc gamma R-specific autoantibodies in patients with autoimmune disease. |
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11. |
Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII. |
Boross P, etal., J Immunol. 2008 Apr 1;180(7):5083-91.
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12. |
On the role of platelet Fc gamma RIIa phenotype in heparin-induced thrombocytopenia. |
Brandt JT, etal., Thromb Haemost. 1995 Dec;74(6):1564-72.
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13. |
No association of Fc gamma RIIa, Fc gamma RIIIa and Fc gamma RIIIb polymorphisms with MS. |
Breij EC, etal., J Neuroimmunol. 2003 Jul;140(1-2):210-5.
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14. |
Common variants in genes that mediate immunity and risk of multiple myeloma. |
Brown EE, etal., Int J Cancer. 2007 Jun 15;120(12):2715-22.
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15. |
Fcgamma receptor IIA genotype and susceptibility to P. aeruginosa infection in patients with cystic fibrosis. |
De Rose V, etal., Eur J Hum Genet. 2005 Jan;13(1):96-101.
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16. |
C-reactive protein stimulates superoxide anion release and tissue factor activity in vivo. |
Devaraj S, etal., Atherosclerosis. 2009 Mar;203(1):67-74. Epub 2008 Jun 13.
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17. |
Associations between Fc gamma receptor IIA polymorphisms and the risk and prognosis of meningococcal disease. |
Domingo P, etal., Am J Med. 2002 Jan;112(1):19-25.
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18. |
Effect of FCGR2A and FCGR3A variants on CLL outcome. |
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19. |
The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A. |
Eckhardt CL, etal., J Thromb Haemost. 2014 Aug;12(8):1294-301. doi: 10.1111/jth.12631. Epub 2014 Jul 16.
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20. |
FcgammaRIIa and FcgammaRIIIa genetic polymorphisms in a group of pediatric immune thrombocytopenic purpura in Egypt. |
Eyada TK, etal., Blood Coagul Fibrinolysis. 2012 Jan;23(1):64-8. doi: 10.1097/MBC.0b013e32834ddf2f.
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21. |
Rat CD16 is defined by a family of class III Fc gamma receptors requiring co-expression of heteroprotein subunits. |
Farber DL and Sears DW, J Immunol 1991 Jun 15;146(12):4352-61.
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22. |
Rat class III Fc gamma receptor isoforms differ in IgG subclass-binding specificity and fail to associate productively with rat CD3 zeta. |
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23. |
The role of Fcgamma receptor polymorphisms and C3 in the immune defence against Neisseria meningitidis in complement-deficient individuals. |
Fijen CA, etal., Clin Exp Immunol. 2000 May;120(2):338-45.
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24. |
[Low-affinity Fcgamma receptor IIa gene polymorphism and dengue bleeding disorder]. |
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25. |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. |
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
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26. |
FCGR3A/2A polymorphisms and diffuse large B-cell lymphoma outcome treated with immunochemotherapy: a meta-analysis on 1134 patients from two prospective cohorts. |
Ghesquieres H, etal., Hematol Oncol. 2016 Jun 10. doi: 10.1002/hon.2305.
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27. |
Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. |
Giorgini A, etal., J Immunol. 2008 Dec 15;181(12):8745-52.
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28. |
Rat ISS GO annotations from GOA human gene data--August 2006 |
GOA data from the GO Consortium
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29. |
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. |
Harley JB, etal., Nat Genet. 2008 Feb;40(2):204-10. Epub 2008 Jan 20.
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30. |
Expression of Fcgamma and complement receptors on peripheral blood monocytes in systemic lupus erythematosus and rheumatoid arthritis. |
Hepburn AL, etal., Rheumatology (Oxford). 2004 May;43(5):547-54. Epub 2004 Jan 27.
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31. |
Dendritic cells modulate platelet activity in IVIg-mediated amelioration of ITP in mice. |
Huang HS, etal., Blood. 2010 Dec 2;116(23):5002-9. doi: 10.1182/blood-2010-03-275123. Epub 2010 Aug 10.
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32. |
Activating Fc gamma receptors participate in the development of autoimmune diabetes in NOD mice. |
Inoue Y, etal., J Immunol. 2007 Jul 15;179(2):764-74.
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33. |
Association between SLE nephritis and polymorphic variants of the CRP and FcgammaRIIIa genes. |
Jonsen A, etal., Rheumatology (Oxford). 2007 Sep;46(9):1417-21. Epub 2007 Jun 27.
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34. |
Decreased expression of both Fc gamma RII and Fc gamma RIII mRNA in leukemic granulocytes. |
Kant A, etal., Leuk Res. 1995 Dec;19(12):997-1000.
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35. |
Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the Fc gamma receptor IIA. |
Kim YS, etal., Blood Coagul Fibrinolysis. 2009 Jul;20(5):353-7.
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36. |
The association between a common FCGR2A polymorphism and C-reactive protein and coronary artery disease revisited. |
Kroupis C, etal., Genet Test Mol Biomarkers. 2010 Dec;14(6):839-46. Epub 2010 Oct 25.
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37. |
Inhibition of hyperacute transplant rejection by soluble proteins with the functional domains of CD46 and FcgammaRII. |
Lanteri MB, etal., Transplantation. 2000 Mar 27;69(6):1128-36.
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38. |
Susceptibility for ischemic stroke in four constitution medicine is associated with polymorphisms of FCGR2A and IL1RN genes. |
Lee BC, etal., Neurol Res. 2010 Feb;32 Suppl 1:43-7.
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39. |
FCGR3A and FCGR2A polymorphisms may not correlate with response to alemtuzumab in chronic lymphocytic leukemia. |
Lin TS, etal., Blood. 2005 Jan 1;105(1):289-91. Epub 2004 Jun 24.
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40. |
High-dose dexamethasone shifts the balance of stimulatory and inhibitory Fcgamma receptors on monocytes in patients with primary immune thrombocytopenia. |
Liu XG, etal., Blood. 2011 Feb 10;117(6):2061-9. doi: 10.1182/blood-2010-07-295477. Epub 2010 Dec 3.
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41. |
The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: a transgenic mouse model. |
McKenzie SE, etal., J Immunol. 1999 Apr 1;162(7):4311-8.
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42. |
FcgammaRIII (CD16)-deficient mice show IgG isotype-dependent protection to experimental autoimmune hemolytic anemia. |
Meyer D, etal., Blood. 1998 Dec 1;92(11):3997-4002.
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43. |
CD32a antibodies induce thrombocytopenia and type II hypersensitivity reactions in FCGR2A mice. |
Meyer T, etal., Blood. 2015 Nov 5;126(19):2230-8. doi: 10.1182/blood-2015-04-638684. Epub 2015 Sep 22.
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44. |
Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice. |
Meyer T, etal., J Thromb Haemost. 2009 Jan;7(1):171-81. doi: 10.1111/j.1538-7836.2008.03212.x. Epub 2008 Oct 30.
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45. |
Gene Data Set |
MGD Curation, June 12, 2002
|
46. |
Rat ISS GO annotations from MGI mouse gene data--August 2006 |
MGD data from the GO Consortium
|
47. |
Association of Fc¿RIIa Polymorphism with Clinical Outcome of Dengue Infection: First Insight from Pakistan. |
Mohsin SN, etal., Am J Trop Med Hyg. 2015 Oct;93(4):691-6. doi: 10.4269/ajtmh.15-0199. Epub 2015 Aug 3.
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48. |
Association of FCGR2A and FCGR2A-FCGR3A haplotypes with susceptibility to giant cell arteritis. |
Morgan AW, etal., Arthritis Res Ther. 2006;8(4):R109.
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49. |
Relationships between eosinophil-associated parameters and disease severity in atopic dermatitis. |
Nakama T Kurume Med J. 1995;42(2):95-106.
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50. |
[The diagnostic of defects of inborn immunity under B-cell tumors of lymphatic system]. |
Nazarova EL, etal., Klin Lab Diagn. 2014 Nov;59(11):39-42.
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51. |
Electronic Transfer of LocusLink and RefSeq Data |
NCBI rat LocusLink and RefSeq merged data July 26, 2002
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52. |
Relationship between Fc receptor IIA polymorphism and infection in children with sickle cell disease. |
Norris CF, etal., J Pediatr. 1996 Jun;128(6):813-9.
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53. |
OMIM Disease Annotation Pipeline |
OMIM Disease Annotation Pipeline
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54. |
Fc gamma RIIa, IIIa and IIIb polymorphisms in Turkish children susceptible to recurrent infectious diseases. |
Ozturk C, etal., Clin Exp Med. 2006 Mar;6(1):27-32.
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55. |
Role of novel rat-specific Fc receptor in macrophage activation associated with crescentic glomerulonephritis. |
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56. |
FcgammaRIIa and FcgammaRIIIa polymorphisms in childhood primary immune thrombocytopenia: implications for disease pathogenesis and outcome. |
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57. |
FC gamma RIIa polymorphism in patients with rheumatoid arthritis. |
Pawlik A, etal., Clin Exp Rheumatol. 2002 Nov-Dec;20(6):841-4.
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58. |
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. |
Pedotti R, etal., Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1867-72. Epub 2003 Feb 7.
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59. |
KEGG Annotation Import Pipeline |
Pipeline to import KEGG annotations from KEGG into RGD
|
60. |
ClinVar Automated Import and Annotation Pipeline |
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
|
61. |
Data Import for Chemical-Gene Interactions |
RGD automated import pipeline for gene-chemical interactions
|
62. |
Comprehensive gene review and curation |
RGD comprehensive gene curation
|
63. |
FcgammaRIII is protective against Pseudomonas aeruginosa pneumonia. |
Rhein LM, etal., Am J Respir Cell Mol Biol. 2008 Apr;38(4):401-6. Epub 2007 Nov 1.
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64. |
Anti-CD40L immune complexes potently activate platelets in vitro and cause thrombosis in FCGR2A transgenic mice. |
Robles-Carrillo L, etal., J Immunol. 2010 Aug 1;185(3):1577-83. Epub 2010 Jun 28.
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65. |
Early atherosclerosis and IgG2 to bacteria are associated with FcgammaRIIa genotype in non-smokers. |
Sampi M, etal., Eur J Clin Invest. 2009 Jun;39(6):517-26.
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66. |
Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus. |
Sanchez E, etal., Ann Rheum Dis. 2011 Jun 30.
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67. |
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. |
Sarvari M, etal., J Neuroinflammation. 2012 Dec 3;9:264. doi: 10.1186/1742-2094-9-264.
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68. |
FCGR2A functional genetic variant associated with susceptibility to severe malarial anaemia in Ghanaian children. |
Schuldt K, etal., J Med Genet. 2010 Jul;47(7):471-5. Epub 2009 Dec 3.
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69. |
Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. |
Sinha S, etal., Malar J. 2008 Jan 14;7:13.
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70. |
The Fcgamma receptor IIA-H/H131 genotype is associated with bacteremia in pneumococcal community-acquired pneumonia. |
Sole-Violan J, etal., Crit Care Med. 2011 Jun;39(6):1388-93.
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71. |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
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72. |
A single-nucleotide polymorphism of the Fcgamma receptor type IIIA gene in the recipient predicts transplant outcomes after HLA fully matched unrelated BMT for myeloid malignancies. |
Takami A, etal., Bone Marrow Transplant. 2011 Feb;46(2):238-43. doi: 10.1038/bmt.2010.88. Epub 2010 Apr 19.
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73. |
FcgammaRIII b and FcgammaRIIa polymorphism may affect the production of specific NA1 autoantibody and clinical course of autoimmune neutropenia of infancy. |
Taniuchi S, etal., Hum Immunol. 2001 Apr;62(4):408-13.
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74. |
A novel splice variant of FcgammaRIIa: a risk factor for anaphylaxis in patients with hypogammaglobulinemia. |
van der Heijden J, etal., J Allergy Clin Immunol. 2013 May;131(5):1408-16.e5. doi: 10.1016/j.jaci.2013.02.009. Epub 2013 Mar 29.
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75. |
A novel human CD32 mAb blocks experimental immune haemolytic anaemia in FcgammaRIIA transgenic mice. |
van Royen-Kerkhof A, etal., Br J Haematol. 2005 Jul;130(1):130-7.
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76. |
Expression of genes encoding receptors for IgG (FcRIII) and for C3b/C4b (Crry) in rat sciatic nerve during development and Wallerian degeneration. |
Vedeler CA, etal., J Neurosci Res. 1992 Apr;31(4):654-61.
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77. |
Phenotypic analysis of alveolar macrophages and monocytes in allergic airway inflammation. I. Evidence for activation of alveolar macrophages, but not peripheral blood monocytes, in subjects with allergic rhinitis and asthma. |
Viksman MY, etal., Am J Respir Crit Care Med. 1997 Mar;155(3):858-63.
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78. |
Mannose binding lectin and FcgammaRIIa (CD32) polymorphism in Spanish systemic lupus erythematosus patients. |
Villarreal J, etal., Rheumatology (Oxford). 2001 Sep;40(9):1009-12.
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79. |
Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations. |
Weersma RK, etal., Inflamm Bowel Dis. 2010 Dec;16(12):2080-9. doi: 10.1002/ibd.21342.
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80. |
Treatment of lupus-prone NZB/NZW F1 mice with recombinant soluble Fc gamma receptor II (CD32). |
Werwitzke S, etal., Ann Rheum Dis. 2008 Feb;67(2):154-61. Epub 2007 Jun 8.
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81. |
Delay of LPS-induced acute lung injury resolution by soluble immune complexes is neutrophil dependent. |
Wu CL, etal., Shock. 2009 Sep;32(3):276-85.
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82. |
Correlation of Fc(gamma)RIIa (CD32) Polymorphism and IgG Antibody Subclasses in Hemolytic Disease of Newborn. |
Wu Q, etal., Neonatology. 2009;96(1):1-5. doi: 10.1159/000189239. Epub 2009 Jan 8.
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83. |
Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis. |
Zaba LC, etal., J Allergy Clin Immunol. 2010 Jun;125(6):1261-1268.e9. Epub 2010 May 14.
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84. |
Characterization and expression of an Fc gamma receptor cDNA cloned from rat natural killer cells. |
Zeger DL, etal., Proc Natl Acad Sci U S A 1990 May;87(9):3425-9.
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