Gene: Dlg1 (discs large MAGUK scaffold protein 1) Rattus norvegicus
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Symbol: Dlg1
Name: discs large MAGUK scaffold protein 1
Description: ENCODES a protein that exhibits ionotropic glutamate receptor binding; kinesin binding; PDZ domain binding; INVOLVED IN cell adhesion; positive regulation of potassium ion transport; regulation of protein localization; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Parkinson Disease; Parkinson's disease; Carcinoma, Ductal, Breast (ortholog); FOUND IN basal plasma membrane; basolateral plasma membrane; cytosol; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; aflatoxin B1
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: discs large homolog 1; discs large homolog 1, scribble cell polarity complex component; discs, large homolog 1; disks large homolog 1; Dlgh1; Drosophila discs-large tumor suppressor homologue (synapse associated protein); SAP-97; SAP97; synapse-associated protein 97
Orthologs:
Homo sapiens (human) : DLG1 (discs large MAGUK scaffold protein 1)  HGNC  AGR
Mus musculus (house mouse) : Dlg1 (discs large MAGUK scaffold protein 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Dlg1 (discs large MAGUK scaffold protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DLG1 (discs large MAGUK scaffold protein 1)
Canis lupus familiaris (dog) : DLG1 (discs large MAGUK scaffold protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlg1 (discs large MAGUK scaffold protein 1)
more info ...
Allele / Splice: Dlg1Tn(sb-T2/Bart3)2.133Mcwi  
Genetic Models: F344-Dlg1Tn(sb-T2/Bart3)2.133Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01172,164,566 - 72,378,895 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01175,389,409 - 75,454,358 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01175,239,783 - 75,349,409 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41170,735,283 - 70,930,374 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11170,792,871 - 70,987,963 (-)NCBI
Celera1168,335,260 - 68,524,109 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dlg1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2505
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE