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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l1
Name: Bcl2-like 1
Acc ID: CHEBI:21759
Term: N-methyl-N'-nitro-N-nitrosoguanidine
Definition: An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position
Chemical ID: MESH:D008769
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1increases expressionISOBcl2l1 (Mus musculus)6480464CTDMethylnitronitrosoguanidine results in increased expression of BCL2L1 mRNAPMID:20434464
Bcl2l1multiple interactionsISOBcl2l1 (Mus musculus)6480464CTDEugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA]PMID:20434464
Bcl2l1multiple interactionsISOBCL2L1 (Homo sapiens)6480464CTDBCL2L1 protein results in decreased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib]PMID:18376143
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