Gene: Flt1 (FMS-related tyrosine kinase 1) Rattus norvegicus
Analyze
Symbol: Flt1
Name: FMS-related tyrosine kinase 1
Description: ENCODES a protein that exhibits ATP binding; growth factor binding; transmembrane receptor protein tyrosine kinase activity; INVOLVED IN activation of MAPKK activity; aging; cellular response to hypoxia; PARTICIPATES IN vascular endothelial growth factor signaling pathway; axitinib pharmacodynamics pathway; bevacizumab pharmacodynamics pathway; ASSOCIATED WITH Acute Lung Injury; Breast Neoplasms; Cerebral Hemorrhage; FOUND IN extracellular space; plasma membrane; actin cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLT-1; FMS-like tyrosine kinase 1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); LOC100911280; tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor 1-like; vascular endothelial growth factor/vascular permeability factor receptor; VEGFR-1
Orthologs:
Homo sapiens (human) : FLT1 (fms related tyrosine kinase 1)  HGNC  AGR
Mus musculus (house mouse) : Flt1 (FMS-like tyrosine kinase 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Flt1 (fms related tyrosine kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FLT1 (fms related tyrosine kinase 1)
Canis lupus familiaris (dog) : FLT1 (fms related tyrosine kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flt1 (fms related tyrosine kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0129,033,993 - 9,205,886 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01210,927,827 - 10,959,880 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4127,858,092 - 8,035,966 (+)NCBIRGSC3.4rn4RGSC3.4
Celera129,039,046 - 9,210,055 (+)NCBICelera
Cytogenetic Map12p11NCBI
RH 3.4 Map12 RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Flt1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2621
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE