Flt1 (FMS-related tyrosine kinase 1)

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Keyword

Gene: Flt1 (FMS-related tyrosine kinase 1) Rattus norvegicus

Symbol:

Flt1

Name:

FMS-related tyrosine kinase 1

Description:

ENCODES a protein that exhibits ATP binding; growth factor binding; transmembrane receptor protein tyrosine kinase activity; INVOLVED IN activation of MAPKK activity; intracellular receptor signaling pathway; positive regulation of cell migration; PARTICIPATES IN vascular endothelial growth factor signaling pathway; axitinib pharmacodynamics pathway; glypican signaling pathway; ASSOCIATED WITH Acute Lung Injury; Breast Neoplasms; Diabetes Mellitus, Experimental; FOUND IN plasma membrane; cytoplasm (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; ammonium chloride

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

FLT-1; FMS-like tyrosine kinase 1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor-1; VEGFR-1

Orthologs:

Homo sapiens : FLT1 (fms-related tyrosine kinase 1) HGNC
Mus musculus : Flt1 (FMS-like tyrosine kinase 1) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	12	p11		NCBI
RGSC Genome Assembly v5.0	12	10,927,827 - 10,959,880	-	NCBI
RGSC Genome Assembly v3.4	12	7,858,092 - 8,035,966	+	NCBI
Rat Celera Assembly	12	9,039,046 - 9,207,940	+	NCBI
Genome Assembly 3.1	12	7,888,019 - 8,065,894	+	NCBI
RH 3.4	12	81.9		RGD