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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621424 Species: Rattus norvegicus RGD Object: Gene Symbol: Lig1 Name: ligase I, DNA, ATP-dependent

Acc ID: CHEBI:21759 Term: N-methyl-N'-nitro-N-nitrosoguanidine Definition: An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position CasRN: 70-25-7 Chemical ID: MESH:D008769

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:731763	6480464	CTD	Methylnitronitrosoguanidine results in decreased expression of LIG1 mRNA	PMID:12634122