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ONTOLOGY REPORT - ANNOTATIONS


Term:phosphatidylcholine metabolic process
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Accession:GO:0046470 term browser browse the term
Definition:The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
Synonyms:exact_synonym: phosphatidylcholine metabolism



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phosphatidylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3709444|PMID:17267394)
(PMID:17574245), (PMID:28887056)
UniProt
RGD
PMID:17267394 PMID:17574245 PMID:28887056 GO_REF:0000024 MGI:3709444 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase involved_in ISO
IBA
(PMID:21926997)
GO_REF:0000033
(MGI:5617348|PMID:21926997)
RGD
GO_Central
PMID:21926997 GO_REF:0000033 MGI:5617348 NCBI chr18:1,723,203...1,778,488
Ensembl chr18:1,720,718...1,803,428
JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
(PMID:1935934)
GO_REF:0000107
RGD
Ensembl
PMID:1935934 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:2590715 RGD:4889588 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO
ISS
(PMID:26195816)
GO_REF:0000024
RGD
UniProt
PMID:26195816 GO_REF:0000024 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:2223857 RGD:1600650 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Mecp2 methyl CpG binding protein 2 acts_upstream_of_or_within ISO MGI:2137311 (PMID:17237885) RGD PMID:17237885 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Pla2g10 phospholipase A2, group X involved_in ISO
IEA
ISS
(PMID:12359733), (PMID:16146426), (PMID:16962371)
GO_REF:0000107
(MGI:2446974|PMID:12359733)
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12359733 PMID:16146426 PMID:16962371 GO_REF:0000024 GO_REF:0000107 MGI:2446974 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in IMP
IBA
ISO
ISS
GO_REF:0000033
(PMID:29724779)
GO_REF:0000024
GO_Central
RGD
UniProt
PMID:29724779 PMID:11238016 GO_REF:0000024 GO_REF:0000033, RGD:1582127 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISO
IEA
(PMID:17603006), (PMID:7060561)
GO_REF:0000107
RGD
Ensembl
PMID:7060561 PMID:17603006 GO_REF:0000107 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in ISO
ISS
(PMID:25082876)
GO_REF:0000024
RGD
UniProt
PMID:25082876 GO_REF:0000024 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Pla2g2d phospholipase A2, group IID involved_in ISO (PMID:10681567)
(MGI:1346886|PMID:10531313)
RGD PMID:10531313 PMID:10681567 MGI:1346886 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525
JBrowse link
G Pla2g2e phospholipase A2, group IIE involved_in ISO (MGI:1346886|PMID:10531313) RGD PMID:10531313 MGI:1346886 NCBI chr 5:151,121,363...151,127,147
Ensembl chr 5:151,121,439...151,126,821
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in
acts_upstream_of_or_within
ISO (PMID:28947740)
MGI:4461174 (PMID:20424323)
RGD PMID:20424323 PMID:28947740 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Plaat1 phospholipase A and acyltransferase 1 involved_in ISO (PMID:21880860) RGD PMID:21880860 NCBI chr11:71,517,492...71,537,142
Ensembl chr11:71,517,493...71,527,020
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
JBrowse link
G Pon1 paraoxonase 1 involved_in ISO
IEA
(PMID:15721011)
GO_REF:0000107
RGD
Ensembl
PMID:15721011 GO_REF:0000107 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
CDP-choline pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cept1 choline/ethanolamine phosphotransferase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
JBrowse link
G Chka choline kinase alpha involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000108
(MGI:3695773|PMID:16861741)
GO_REF:0000033
GOC
RGD
GO_Central
PMID:16861741 GO_REF:0000033 GO_REF:0000108 MGI:3695773 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Chkb choline kinase beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461
JBrowse link
G Chpt1 choline phosphotransferase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline involved_in IDA
ISO
PMID:19783652
(MGI:2667298|PMID:12842190)
PMID:8185307
(PMID:10480912)
PMID:8381041
RGD PMID:10480912 PMID:12842190 PMID:19783652 PMID:8185307 PMID:8381041 MGI:2667298, RGD:8553740, RGD:39458015, RGD:729578 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
JBrowse link
G Pcyt1b phosphate cytidylyltransferase 1B, choline involved_in IEA
ISO
ISS
GO_REF:0000107
GO_REF:0000002
(MGI:2667298|PMID:12842190)
GO_REF:0000024
(PMID:10480912)
Ensembl
InterPro
RGD
UniProt
PMID:10480912 PMID:12842190 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:2667298 NCBI chr  X:58,378,090...58,471,623
Ensembl chr  X:58,378,116...58,468,935
JBrowse link
G Phka1 phosphorylase kinase regulatory subunit alpha 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:67,601,302...67,738,504
Ensembl chr  X:67,601,302...67,738,455
JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of_or_within ISO (PMID:20018880) RGD PMID:20018880 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401
JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:2302419) RGD PMID:2302419 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
phosphatidylcholine acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbi diazepam binding inhibitor involved_in ISO (PMID:21079819) RGD PMID:21079819 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 involved_in ISO (PMID:21498505) RGD PMID:21498505 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401
JBrowse link
G Lpcat2 lysophosphatidylcholine acyltransferase 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:21498505)
Ensembl
RGD
PMID:21498505 GO_REF:0000107 NCBI chr19:14,088,389...14,152,742
Ensembl chr19:14,089,686...14,152,829
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISO
ISS
(PMID:18195019), (PMID:18772128), (PMID:18782225)
(MGI:5548036|PMID:24206663), (MGI:5636535|PMID:25806685), (MGI:5751339|PMID:25898003), (MGI:5927299|PMID:28846071), (MGI:6436389|PMID:18287005)
GO_REF:0000024
RGD
UniProt
PMID:18195019 PMID:18287005 PMID:18772128 PMID:18782225 PMID:24206663 More... GO_REF:0000024 MGI:5548036 MGI:5636535 MGI:5751339 MGI:5927299 MGI:6436389 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 involved_in ISO (PMID:18458083)
(MGI:3772495|PMID:18156367)
RGD PMID:18156367 PMID:18458083 MGI:3772495 NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875
JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 involved_in ISO
ISS
(PMID:18772128)
(MGI:6436389|PMID:18287005)
GO_REF:0000024
RGD
UniProt
PMID:18287005 PMID:18772128 GO_REF:0000024 MGI:6436389 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 involved_in ISO (PMID:18772128) RGD PMID:18772128 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5548036|PMID:24206663)
UniProt
Ensembl
RGD
PMID:24206663 GO_REF:0000024 GO_REF:0000107 MGI:5548036 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5548036|PMID:24206663)
UniProt
RGD
PMID:24206663 GO_REF:0000024 MGI:5548036 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Pla2g2f phospholipase A2, group IIF involved_in ISO (PMID:11112443) RGD PMID:11112443 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175
JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO
IEA
(PMID:16617059)
GO_REF:0000107
RGD
Ensembl
PMID:16617059 GO_REF:0000107 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g4b phospholipase A2 group IVB involved_in ISO (PMID:10358058), (PMID:16617059) RGD PMID:10358058 PMID:16617059 NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853
JBrowse link
G Pla2g4c phospholipase A2 group IVC involved_in ISO (PMID:19501189) RGD PMID:19501189 NCBI chr 1:74,237,714...74,275,757
Ensembl chr 1:74,236,211...74,274,656
JBrowse link
phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in ISO
IEA
(PMID:4335615)
GO_REF:0000107
RGD
Ensembl
PMID:4335615 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 acts_upstream_of_or_within ISO (PMID:20018880) RGD PMID:20018880 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
JBrowse link
G Chka choline kinase alpha involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:16371353)
(PMID:34077757)
(PMID:19915674)
UniProt
RGD
PMID:16371353 PMID:19915674 PMID:34077757 GO_REF:0000024 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Chkb choline kinase beta acts_upstream_of_or_within ISO MGI:3578417 (PMID:16371353) RGD PMID:16371353 NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461
JBrowse link
G Chpt1 choline phosphotransferase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:10893425)
(PMID:20018880)
RGD PMID:10893425 PMID:20018880 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:28930673)
Ensembl
RGD
PMID:28930673 GO_REF:0000107 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
JBrowse link
G Fabp5 fatty acid binding protein 5 acts_upstream_of_or_within ISO MGI:95476 (PMID:15164767) RGD PMID:15164767 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fgf7 fibroblast growth factor 7 IMP surfactant disaturated phosphatidylcholine (DSPC) synthesis RGD PMID:11316745 RGD:68696 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 involved_in ISO (PMID:18238778) RGD PMID:18238778 NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901
JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO
IEA
(PMID:11966470), (PMID:12354767)
GO_REF:0000107
RGD
Ensembl
PMID:11966470 PMID:12354767 GO_REF:0000107 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of ISO (PMID:20018880) RGD PMID:20018880 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline acts_upstream_of_or_within
involved_in
TAS
ISO
IDA
IMP
MGI:2176050|MGI:3027956 (PMID:11829742), (PMID:15798219)
(MGI:2667298|PMID:12842190)
PMID:8381041
PMID:8185307
(PMID:10480912)
RGD PMID:10480912 PMID:11829742 PMID:12842190 PMID:15798219 PMID:2166941 More... MGI:2667298, RGD:70012, RGD:729578, RGD:39458015, RGD:729598 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
JBrowse link
G Pcyt1b phosphate cytidylyltransferase 1B, choline involved_in ISO
ISS
(PMID:10480912)
(MGI:2667298|PMID:12842190)
GO_REF:0000024
RGD
UniProt
PMID:10480912 PMID:12842190 GO_REF:0000024 MGI:2667298 NCBI chr  X:58,378,090...58,471,623
Ensembl chr  X:58,378,116...58,468,935
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase involved_in IDA
IBA
IEA
GO_REF:0000033
GO_REF:0000041
GO_Central
UniProt
RGD
PMID:8344945 GO_REF:0000033 GO_REF:0000041, RGD:729486 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link
G Phka1 phosphorylase kinase regulatory subunit alpha 1 TAS RGD PMID:12401806 RGD:724642 NCBI chr  X:67,601,302...67,738,504
Ensembl chr  X:67,601,302...67,738,455
JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO
IEA
(PMID:19523918)
GO_REF:0000118
GO_REF:0000107
RGD
TreeGrafter
Ensembl
PMID:19523918 GO_REF:0000107 GO_REF:0000118 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in ISO
IBA
IEA
IDA
(PMID:21240271)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(MGI:5050048|PMID:21240269)
RGD
GO_Central
TreeGrafter
Ensembl
PMID:21240269 PMID:21240271 PMID:21240271 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5050048, RGD:8553522 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 involved_in ISO (MGI:5616003|PMID:25528375) RGD PMID:25528375 MGI:5616003 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063
JBrowse link
G Pla2g10 phospholipase A2, group X involved_in ISO (PMID:12021277) RGD PMID:12021277 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in ISS
ISO
GO_REF:0000024
(MGI:3654404|PMID:16880524), (MGI:3694368|PMID:16837646), (MGI:6392937|PMID:17626977)
UniProt
RGD
PMID:16837646 PMID:16880524 PMID:17626977 GO_REF:0000024 MGI:3654404 MGI:3694368 MGI:6392937 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO
IEA
ISS
(PMID:12672805), (PMID:14709560), (PMID:17472963), (PMID:7794891), (PMID:9425121)
GO_REF:0000107
(MGI:1100763|PMID:9403693)
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:7794891 PMID:9403693 PMID:9425121 PMID:12672805 PMID:14709560 More... GO_REF:0000024 GO_REF:0000107 MGI:1100763 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:23533611)
UniProt
Ensembl
RGD
PMID:23533611 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:20886109)
UniProt
Ensembl
RGD
PMID:20886109 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:2040620) RGD PMID:2040620 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plb1 phospholipase B1 involved_in IDA PMID:9442065
PMID:9442064
UniProt PMID:9442065 PMID:9442064 RGD:633237, RGD:30309923 NCBI chr 6:24,087,051...24,227,167
Ensembl chr 6:24,089,214...24,210,117
JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 involved_in ISO
ISS
(PMID:17401110)
GO_REF:0000024
RGD
UniProt
PMID:17401110 GO_REF:0000024 NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6393153|PMID:28887301)
UniProt
Ensembl
RGD
PMID:28887301 GO_REF:0000024 GO_REF:0000107 MGI:6393153 NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497
JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 involved_in ISO (PMID:15695510) RGD PMID:15695510 NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734
JBrowse link
phosphatidylethanolamine acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5751339|PMID:25898003), (MGI:6436389|PMID:18287005)
(PMID:18772128), (PMID:18782225)
UniProt
RGD
PMID:18287005 PMID:18772128 PMID:18782225 PMID:25898003 GO_REF:0000024 MGI:5751339 MGI:6436389 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 involved_in ISO (PMID:18458083) RGD PMID:18458083 NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 involved_in ISO (MGI:6889980|PMID:35131264) RGD PMID:35131264 MGI:6889980 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 involved_in ISO (MGI:6436389|PMID:18287005) RGD PMID:18287005 MGI:6436389 NCBI chr17:34,331,413...34,445,088
Ensembl chr17:34,331,422...34,445,088
JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 involved_in ISO
ISS
(PMID:18772128)
(MGI:6436389|PMID:18287005)
GO_REF:0000024
RGD
UniProt
PMID:18287005 PMID:18772128 GO_REF:0000024 MGI:6436389 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485
JBrowse link
G Pla2g2f phospholipase A2, group IIF involved_in ISO (PMID:11112443)
(MGI:6467677|PMID:11877435)
RGD PMID:11112443 PMID:11877435 MGI:6467677 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175
JBrowse link
G Pla2g4b phospholipase A2 group IVB involved_in ISO (PMID:16617059) RGD PMID:16617059 NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853
JBrowse link
G Pla2g4c phospholipase A2 group IVC involved_in ISO (PMID:19501189) RGD PMID:19501189 NCBI chr 1:74,237,714...74,275,757
Ensembl chr 1:74,236,211...74,274,656
JBrowse link
positive regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long-chain family member 3 involved_in ISO
IEA
(PMID:18003621)
GO_REF:0000107
RGD
Ensembl
PMID:18003621 GO_REF:0000107 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Capn2 calpain 2 IMP RGD PMID:9481489 RGD:13792658 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Rab38 RAB38, member RAS oncogene family IDA RGD PMID:28438206 RGD:13524861 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924
JBrowse link
regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp3 fatty acid binding protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:101790 (PMID:15164767)
Ensembl
RGD
PMID:15164767 GO_REF:0000107 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in ISO
IEA
(MGI:3784112|PMID:18175806)
GO_REF:0000107
RGD
Ensembl
PMID:18175806 GO_REF:0000107 MGI:3784112 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO
IEA
(MGI:3784112|PMID:18175806)
GO_REF:0000107
RGD
Ensembl
PMID:18175806 GO_REF:0000107 MGI:3784112 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
regulation of phosphatidylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:25817392), (PMID:31473345)
UniProt
RGD
PMID:25817392 PMID:31473345 GO_REF:0000024 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of ISO (PMID:26005868)
(MGI:6196220|PMID:30074985)
RGD PMID:26005868 PMID:30074985 MGI:6196220 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      organic substance metabolic process 11221
        organonitrogen compound metabolic process 5790
          phosphatidylcholine metabolic process 65
            1,2-diacyl-sn-glycero-3-phosphocholine metabolic process 0
            negative regulation of phosphatidylcholine metabolic process + 2
            phosphatidylcholine acyl-chain remodeling 13
            phosphatidylcholine biosynthetic process + 22
            phosphatidylcholine catabolic process + 15
            phosphatidylethanolamine acyl-chain remodeling 8
            positive regulation of phosphatidylcholine metabolic process + 3
            regulation of phosphatidylcholine metabolic process + 10
Path 2
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      cellular metabolic process 10279
        phosphorus metabolic process 1934
          phosphate-containing compound metabolic process 1906
            phospholipid metabolic process 385
              glycerophospholipid metabolic process 289
                phosphatidylcholine metabolic process 65
                  1,2-diacyl-sn-glycero-3-phosphocholine metabolic process 0
                  negative regulation of phosphatidylcholine metabolic process + 2
                  phosphatidylcholine acyl-chain remodeling 13
                  phosphatidylcholine biosynthetic process + 22
                  phosphatidylcholine catabolic process + 15
                  phosphatidylethanolamine acyl-chain remodeling 8
                  positive regulation of phosphatidylcholine metabolic process + 3
                  regulation of phosphatidylcholine metabolic process + 10
paths to the root