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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphatidylcholine metabolic process
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Accession:GO:0046470 term browser browse the term
Definition:The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
Synonyms:exact_synonym: phosphatidylcholine metabolism


show annotations for term's descendants           Sort by:
phosphatidylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3709444|PMID:17267394)
(PMID:17574245), (PMID:28887056)		 UniProt
RGD		 PMID:17267394 PMID:17574245 PMID:28887056 GO_REF:0000024 MGI:3709444 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase involved_in ISO
IBA		 (PMID:21926997)
(MGI:5617348|PMID:21926997)
PMID:21873635		 RGD PMID:21926997 PMID:21873635 MGI:5617348, RGD:13792537 NCBI chr18:1,723,203...1,778,488
Ensembl chr18:1,720,718...1,803,428 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO
IEA
IBA		 (PMID:1935934)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:1935934 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:2590715 RGD:4889588 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO
ISS		 (PMID:26195816)
GO_REF:0000024		 RGD
UniProt		 PMID:26195816 GO_REF:0000024 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:2223857 RGD:1600650 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Mecp2 methyl CpG binding protein 2 acts_upstream_of_or_within ISO MGI:2137311 (MGI:3769075|PMID:17237885) RGD PMID:17237885 MGI:3769075 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in ISO
IEA
ISS		 (PMID:12359733), (PMID:16146426), (PMID:16962371)
GO_REF:0000107
(MGI:2446974|PMID:12359733)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12359733 PMID:16146426 PMID:16962371 GO_REF:0000024 GO_REF:0000107 MGI:2446974 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in IMP
IBA
ISO
ISS		 PMID:21873635
(PMID:29724779)
GO_REF:0000024		 RGD
UniProt		 PMID:29724779 PMID:11238016 PMID:21873635 GO_REF:0000024, RGD:1582127, RGD:13792537 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063 		JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISO
IEA		 (PMID:17603006), (PMID:7060561)
GO_REF:0000107		 RGD
Ensembl		 PMID:7060561 PMID:17603006 GO_REF:0000107 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226 		JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in ISO
ISS		 (PMID:25082876)
GO_REF:0000024		 RGD
UniProt		 PMID:25082876 GO_REF:0000024 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g2d phospholipase A2, group IID involved_in ISO (PMID:10681567)
(MGI:1346886|PMID:10531313)		 RGD PMID:10531313 PMID:10681567 MGI:1346886 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Pla2g2e phospholipase A2, group IIE involved_in ISO (MGI:1346886|PMID:10531313) RGD PMID:10531313 MGI:1346886 NCBI chr 5:151,121,392...151,127,157
Ensembl chr 5:151,121,439...151,126,821 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in
acts_upstream_of_or_within		 ISO (PMID:28947740)
MGI:4461174 (MGI:4459354|PMID:20424323)		 RGD PMID:20424323 PMID:28947740 MGI:4459354 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Plaat1 phospholipase A and acyltransferase 1 involved_in ISO (PMID:21880860) RGD PMID:21880860 NCBI chr11:71,517,492...71,537,142
Ensembl chr11:71,517,493...71,527,020 		JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734 		JBrowse link
G Pon1 paraoxonase 1 involved_in ISO
IEA		 (PMID:15721011)
GO_REF:0000107		 RGD
Ensembl		 PMID:15721011 GO_REF:0000107 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
CDP-choline pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cept1 choline/ethanolamine phosphotransferase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578 		JBrowse link
G Chka choline kinase alpha involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
(MGI:3695773|PMID:16861741)
GO_REF:0000108		 RGD
GOC		 PMID:16861741 PMID:21873635 GO_REF:0000108 MGI:3695773, RGD:13792537 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Chkb choline kinase beta involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3578417 (MGI:3623691|PMID:16371353)		 RGD PMID:16371353 PMID:21873635 MGI:3623691, RGD:13792537 NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461 		JBrowse link
G Chpt1 choline phosphotransferase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103 		JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline involved_in IDA
ISO		 PMID:19783652
(MGI:2667298|PMID:12842190)
PMID:8185307
(PMID:10480912)
PMID:8381041		 RGD PMID:10480912 PMID:12842190 PMID:19783652 PMID:8185307 PMID:8381041 MGI:2667298, RGD:8553740, RGD:39458015, RGD:729578 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357 		JBrowse link
G Pcyt1b phosphate cytidylyltransferase 1B, choline involved_in IEA
ISO
ISS		 GO_REF:0000107
GO_REF:0000002
(MGI:2667298|PMID:12842190)
GO_REF:0000024
(PMID:10480912)		 Ensembl
InterPro
RGD
UniProt		 PMID:10480912 PMID:12842190 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:2667298 NCBI chr  X:58,378,090...58,471,623
Ensembl chr  X:58,378,116...58,468,935 		JBrowse link
G Phka1 phosphorylase kinase regulatory subunit alpha 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:67,601,302...67,738,504
Ensembl chr  X:67,601,302...67,738,455 		JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of_or_within ISO (MGI:4460850|PMID:20018880) RGD PMID:20018880 MGI:4460850 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401 		JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:2302419) RGD PMID:2302419 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
phosphatidylcholine acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbi diazepam binding inhibitor involved_in ISO (PMID:21079819) RGD PMID:21079819 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 involved_in ISO (PMID:21498505) RGD PMID:21498505 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401 		JBrowse link
G Lpcat2 lysophosphatidylcholine acyltransferase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21498505)		 Ensembl
RGD		 PMID:21498505 GO_REF:0000107 NCBI chr19:14,088,389...14,152,742
Ensembl chr19:14,089,686...14,152,829 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISO
ISS		 (PMID:18195019), (PMID:18772128), (PMID:18782225)
(MGI:5548036|PMID:24206663), (MGI:5636535|PMID:25806685), (MGI:5751339|PMID:25898003), (MGI:5927299|PMID:28846071), (MGI:6436389|PMID:18287005)
GO_REF:0000024		 RGD
UniProt		 PMID:18195019 PMID:18287005 PMID:18772128 PMID:18782225 PMID:24206663 More... GO_REF:0000024 MGI:5548036 MGI:5636535 MGI:5751339 MGI:5927299 MGI:6436389 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 involved_in ISO (PMID:18458083)
(MGI:3772495|PMID:18156367)		 RGD PMID:18156367 PMID:18458083 MGI:3772495 NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 involved_in ISO
ISS		 (PMID:18772128)
(MGI:6436389|PMID:18287005)
GO_REF:0000024		 RGD
UniProt		 PMID:18287005 PMID:18772128 GO_REF:0000024 MGI:6436389 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485 		JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 involved_in ISO (PMID:18772128) RGD PMID:18772128 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5548036|PMID:24206663)		 UniProt
Ensembl
RGD		 PMID:24206663 GO_REF:0000024 GO_REF:0000107 MGI:5548036 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5548036|PMID:24206663)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24206663 GO_REF:0000024 GO_REF:0000107 MGI:5548036 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Pla2g2f phospholipase A2, group IIF involved_in ISO (PMID:11112443) RGD PMID:11112443 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO
IEA		 (PMID:16617059)
GO_REF:0000107		 RGD
Ensembl		 PMID:16617059 GO_REF:0000107 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pla2g4b phospholipase A2 group IVB involved_in ISO (PMID:10358058), (PMID:16617059) RGD PMID:10358058 PMID:16617059 NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853 		JBrowse link
G Pla2g4c phospholipase A2 group IVC involved_in ISO (PMID:19501189) RGD PMID:19501189 NCBI chr 1:74,249,688...74,272,133
Ensembl chr 1:74,236,211...74,274,656 		JBrowse link
phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in ISO
IEA		 (PMID:4335615)
GO_REF:0000107		 RGD
Ensembl		 PMID:4335615 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) RGD PMID:14967812 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 acts_upstream_of_or_within ISO (MGI:4460850|PMID:20018880) RGD PMID:20018880 MGI:4460850 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578 		JBrowse link
G Chka choline kinase alpha involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:34077757)
(MGI:3623691|PMID:16371353)
(PMID:19915674)		 UniProt
RGD		 PMID:16371353 PMID:19915674 PMID:34077757 GO_REF:0000024 MGI:3623691 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Chkb choline kinase beta acts_upstream_of_or_within ISO MGI:3578417 (MGI:3623691|PMID:16371353) RGD PMID:16371353 MGI:3623691 NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461 		JBrowse link
G Chpt1 choline phosphotransferase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:10893425)
(MGI:4460850|PMID:20018880)		 RGD PMID:10893425 PMID:20018880 MGI:4460850 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103 		JBrowse link
G Dhrs7b dehydrogenase/reductase 7B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6103958|PMID:28930673)
GO_REF:0000107		 RGD
Ensembl		 PMID:28930673 GO_REF:0000107 MGI:6103958 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076 		JBrowse link
G Fabp5 fatty acid binding protein 5 acts_upstream_of_or_within ISO MGI:95476 (MGI:3045488|PMID:15164767) RGD PMID:15164767 MGI:3045488 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Fgf7 fibroblast growth factor 7 IMP surfactant disaturated phosphatidylcholine (DSPC) synthesis RGD PMID:11316745 RGD:68696 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 involved_in ISO (PMID:18238778) RGD PMID:18238778 NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901 		JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in ISO
IEA		 (PMID:11966470), (PMID:12354767)
GO_REF:0000107		 RGD
Ensembl		 PMID:11966470 PMID:12354767 GO_REF:0000107 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of ISO (MGI:4460850|PMID:20018880) RGD PMID:20018880 MGI:4460850 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline acts_upstream_of_or_within
involved_in		 TAS
ISO
IDA
IMP		 MGI:2176050|MGI:3027956 (MGI:2159547|PMID:11829742), (MGI:3575987|PMID:15798219)
(MGI:2667298|PMID:12842190)
PMID:8381041
PMID:8185307
(PMID:10480912)		 RGD PMID:10480912 PMID:11829742 PMID:12842190 PMID:15798219 PMID:2166941 More... MGI:2159547 MGI:2667298 MGI:3575987, RGD:70012, RGD:729578, RGD:39458015, RGD:729598 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357 		JBrowse link
G Pcyt1b phosphate cytidylyltransferase 1B, choline involved_in ISO
ISS		 (PMID:10480912)
(MGI:2667298|PMID:12842190)
GO_REF:0000024		 RGD
UniProt		 PMID:10480912 PMID:12842190 GO_REF:0000024 MGI:2667298 NCBI chr  X:58,378,090...58,471,623
Ensembl chr  X:58,378,116...58,468,935 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase involved_in IDA
IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt
RGD		 PMID:8344945 PMID:21873635 GO_REF:0000041, RGD:729486, RGD:13792537 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G Phka1 phosphorylase kinase regulatory subunit alpha 1 TAS RGD PMID:12401806 RGD:724642 NCBI chr  X:67,601,302...67,738,504
Ensembl chr  X:67,601,302...67,738,455 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO
IEA
IBA		 (PMID:19523918)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:19523918 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in IBA
IEA
ISO
IDA		 PMID:21873635
GO_REF:0000107
(MGI:5050048|PMID:21240269)
PMID:21240271
(PMID:21240271)		 Ensembl
RGD		 PMID:21240269 PMID:21240271 PMID:21873635 PMID:21240271 GO_REF:0000107 MGI:5050048, RGD:13792537, RGD:8553522 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 involved_in ISO (MGI:5616003|PMID:25528375) RGD PMID:25528375 MGI:5616003 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in ISO (PMID:12021277) RGD PMID:12021277 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in ISS
ISO		 GO_REF:0000024
(MGI:3654404|PMID:16880524), (MGI:3694368|PMID:16837646), (MGI:6392937|PMID:17626977)		 UniProt
RGD		 PMID:16837646 PMID:16880524 PMID:17626977 GO_REF:0000024 MGI:3654404 MGI:3694368 MGI:6392937 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063 		JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO
IEA
ISS		 (PMID:12672805), (PMID:14709560), (PMID:17472963), (PMID:7794891), (PMID:9425121)
GO_REF:0000107
(MGI:1100763|PMID:9403693)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:7794891 PMID:9403693 PMID:9425121 PMID:12672805 PMID:14709560 More... GO_REF:0000024 GO_REF:0000107 MGI:1100763 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23533611)		 UniProt
Ensembl
RGD		 PMID:23533611 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20886109)		 UniProt
Ensembl
RGD		 PMID:20886109 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:2040620) RGD PMID:2040620 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476 		JBrowse link
G Plb1 phospholipase B1 involved_in IDA PMID:9442065
PMID:9442064		 UniProt PMID:9442065 PMID:9442064 RGD:633237, RGD:30309923 NCBI chr 6:24,087,051...24,227,167
Ensembl chr 6:24,089,214...24,210,117 		JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 involved_in ISO
ISS		 (PMID:17401110)
GO_REF:0000024		 RGD
UniProt		 PMID:17401110 GO_REF:0000024 NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434 		JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6393153|PMID:28887301)		 UniProt
Ensembl
RGD		 PMID:28887301 GO_REF:0000024 GO_REF:0000107 MGI:6393153 NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497 		JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 involved_in ISO (PMID:15695510) RGD PMID:15695510 NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734 		JBrowse link
phosphatidylethanolamine acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5751339|PMID:25898003), (MGI:6436389|PMID:18287005)
(PMID:18772128), (PMID:18782225)		 UniProt
RGD		 PMID:18287005 PMID:18772128 PMID:18782225 PMID:25898003 GO_REF:0000024 MGI:5751339 MGI:6436389 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 involved_in ISO (PMID:18458083) RGD PMID:18458083 NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875 		JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 involved_in ISO (MGI:6889980|PMID:35131264) RGD PMID:35131264 MGI:6889980 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333 		JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 involved_in ISO (MGI:6436389|PMID:18287005) RGD PMID:18287005 MGI:6436389 NCBI chr17:34,331,413...34,445,088
Ensembl chr17:34,331,422...34,445,088 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 involved_in ISO
ISS		 (PMID:18772128)
(MGI:6436389|PMID:18287005)
GO_REF:0000024		 RGD
UniProt		 PMID:18287005 PMID:18772128 GO_REF:0000024 MGI:6436389 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485 		JBrowse link
G Pla2g2f phospholipase A2, group IIF involved_in ISO (PMID:11112443)
(MGI:6467677|PMID:11877435)		 RGD PMID:11112443 PMID:11877435 MGI:6467677 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Pla2g4b phospholipase A2 group IVB involved_in ISO (PMID:16617059) RGD PMID:16617059 NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853 		JBrowse link
G Pla2g4c phospholipase A2 group IVC involved_in ISO (PMID:19501189) RGD PMID:19501189 NCBI chr 1:74,249,688...74,272,133
Ensembl chr 1:74,236,211...74,274,656 		JBrowse link
positive regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long-chain family member 3 involved_in ISO
IEA		 (PMID:18003621)
GO_REF:0000107		 RGD
Ensembl		 PMID:18003621 GO_REF:0000107 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Capn2 calpain 2 IMP RGD PMID:9481489 RGD:13792658 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969 		JBrowse link
G Rab38 RAB38, member RAS oncogene family IDA RGD PMID:28438206 RGD:13524861 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp3 fatty acid binding protein 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:101790 (MGI:3045488|PMID:15164767)
GO_REF:0000107		 RGD
Ensembl		 PMID:15164767 GO_REF:0000107 MGI:3045488 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in ISO
IEA		 (MGI:3784112|PMID:18175806)
GO_REF:0000107		 RGD
Ensembl		 PMID:18175806 GO_REF:0000107 MGI:3784112 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO
IEA		 (MGI:3784112|PMID:18175806)
GO_REF:0000107		 RGD
Ensembl		 PMID:18175806 GO_REF:0000107 MGI:3784112 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
regulation of phosphatidylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25817392), (PMID:31473345)		 UniProt
RGD		 PMID:25817392 PMID:31473345 GO_REF:0000024 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of ISO (PMID:26005868)
(MGI:6196220|PMID:30074985)		 RGD PMID:26005868 PMID:30074985 MGI:6196220 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      nitrogen compound metabolic process 8258
        organonitrogen compound metabolic process 6766
          phosphatidylcholine metabolic process 65
            1,2-diacyl-sn-glycero-3-phosphocholine metabolic process 0
            negative regulation of phosphatidylcholine metabolic process + 2
            phosphatidylcholine acyl-chain remodeling 13
            phosphatidylcholine biosynthetic process + 22
            phosphatidylcholine catabolic process + 15
            phosphatidylethanolamine acyl-chain remodeling 8
            positive regulation of phosphatidylcholine metabolic process + 3
            regulation of phosphatidylcholine metabolic process + 10
Path 2
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      primary metabolic process 8928
        lipid metabolic process 1448
          cellular lipid metabolic process 1052
            glycerolipid metabolic process 388
              glycerophospholipid metabolic process 283
                phosphatidylcholine metabolic process 65
                  1,2-diacyl-sn-glycero-3-phosphocholine metabolic process 0
                  negative regulation of phosphatidylcholine metabolic process + 2
                  phosphatidylcholine acyl-chain remodeling 13
                  phosphatidylcholine biosynthetic process + 22
                  phosphatidylcholine catabolic process + 15
                  phosphatidylethanolamine acyl-chain remodeling 8
                  positive regulation of phosphatidylcholine metabolic process + 3
                  regulation of phosphatidylcholine metabolic process + 10
paths to the root