Pla2g10 (phospholipase A2, group X) - Rat Genome Database

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Gene: Pla2g10 (phospholipase A2, group X) Rattus norvegicus
Analyze
Symbol: Pla2g10
Name: phospholipase A2, group X
RGD ID: 61935
Description: Enables phospholipase A2 activity. Predicted to be involved in several processes, including cholesterol homeostasis; glycerophospholipid metabolic process; and positive regulation of lipid localization. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; erythrocyte maturation; and negative regulation of cytokine production involved in inflammatory response. Predicted to be located in acrosomal vesicle and extracellular space. Orthologous to human PLA2G10 (phospholipase A2 group X); PARTICIPATES IN alpha-linolenic acid metabolic pathway; arachidonic acid metabolic pathway; ether lipid metabolic pathway; INTERACTS WITH 17beta-estradiol; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: group 10 secretory phospholipase A2; group X phospholipase A2; group X secretory phospholipase A2; GX sPLA2; phosphatidylcholine 2-acylhydrolase 10; phosphatidylcholine 2-acylhydrolase GX; phospholipase A2 group X; phospholipase A2, group 10; PLA2GX; sPLA2-X
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8102,104,927 - 2,117,998 (-)NCBIGRCr8
mRatBN7.2101,597,761 - 1,610,822 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl101,597,761 - 1,609,000 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx106,294,586 - 6,305,824 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01034,260,010 - 34,271,250 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0101,612,004 - 1,623,245 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0101,509,732 - 1,520,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl101,509,732 - 1,520,970 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010406,661 - 417,899 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41026,035 - 37,273 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11026,034 - 37,266 (-)NCBI
Celera10658,651 - 669,889 (-)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Pla2g10Rat(+)-catechin multiple interactionsISORGD:7364276480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of PLA2G10 mRNACTDPMID:24763279
Pla2g10Rat1,2-dimethylhydrazine decreases expressionISORGD:6222864804641,2-Dimethylhydrazine results in decreased expression of PLA2G10 mRNACTDPMID:22206623
Pla2g10Rat17alpha-ethynylestradiol affects expressionISORGD:622286480464Ethinyl Estradiol affects the expression of PLA2G10 mRNACTDPMID:17555576
Pla2g10Rat17alpha-ethynylestradiol increases expressionISORGD:622286480464Ethinyl Estradiol results in increased expression of PLA2G10 mRNACTDPMID:17942748
Pla2g10Rat17alpha-ethynylestradiol multiple interactionsISORGD:622286480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PLA2G10 mRNACTDPMID:17942748
Pla2g10Rat17beta-estradiol increases expressionISORGD:7364276480464Estradiol results in increased expression of PLA2G10 mRNACTDPMID:21185374
Pla2g10Rat17beta-estradiol decreases expressionISORGD:7364276480464Estradiol results in decreased expression of PLA2G10 mRNACTDPMID:31614463
Pla2g10Rat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in increased expression of PLA2G10 mRNACTDPMID:26496021
Pla2g10Rat17beta-estradiol multiple interactionsISORGD:7364276480464Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of PLA2G10 mRNA]CTDPMID:21185374
Pla2g10Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:622286480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PLA2G10 mRNACTDPMID:17942748
Pla2g10Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:622286480464Tetrachlorodibenzodioxin affects the expression of PLA2G10 mRNACTDPMID:21570461
Pla2g10Rat3,7-dihydropurine-6-thione decreases expressionEXP 6480464Mercaptopurine results in decreased expression of PLA2G10 mRNACTDPMID:23358152
Pla2g10Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PLA2G10 mRNACTDPMID:30047161
Pla2g10Rataflatoxin B1 increases methylationISORGD:7364276480464Aflatoxin B1 results in increased methylation of PLA2G10 polyA tailCTDPMID:30157460
Pla2g10Ratall-trans-retinoic acid decreases expressionISORGD:622286480464Tretinoin results in decreased expression of PLA2G10 mRNACTDPMID:16604517
Pla2g10Ratall-trans-retinoic acid multiple interactionsISORGD:622286480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PLA2G10 mRNACTDPMID:36189433
Pla2g10Ratall-trans-retinoic acid increases expressionISORGD:7364276480464Tretinoin results in increased expression of PLA2G10 mRNACTDPMID:23830798
Pla2g10Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of PLA2G10 mRNACTDPMID:30047161
Pla2g10Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of PLA2G10 mRNACTDPMID:16483693
Pla2g10RatAzoxymethane multiple interactionsISORGD:622286480464[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PLA2G10 more ...CTDPMID:29950665

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Biological Process
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Object Symbol
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Original Reference(s)
Pla2g10Ratarachidonate secretion involved_inIEAInterPro:IPR016090|InterPro:IPR0364441600115GO_REF:0000002InterProGO_REF:0000002
Pla2g10Rataxon guidance acts_upstream_of_or_withinISORGD:7364271624291 PMID:15927955RGDPMID:15927955
Pla2g10Ratcellular response to leukemia inhibitory factor acts_upstream_of_or_withinISORGD:622281624291 PMID:20439489RGDPMID:20439489
Pla2g10Ratcellular response to leukemia inhibitory factor acts_upstream_of_or_withinIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Ratcholesterol homeostasis involved_inISORGD:622281624291 PMID:20844270RGDPMID:20844270
Pla2g10Ratcholesterol homeostasis involved_inIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Ratdefense response to virus involved_inISORGD:7364271624291 PMID:16146426RGDPMID:16146426
Pla2g10Raterythrocyte maturation acts_upstream_of_or_withinIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Raterythrocyte maturation acts_upstream_of_or_withinISORGD:622281624291MGI:4412409 PMID:26828067RGDPMID:26828067
Pla2g10Ratfertilization acts_upstream_of_or_withinISORGD:622281624291MGI:4412409 PMID:26828067RGDPMID:26828067
Pla2g10Ratfertilization acts_upstream_of_or_withinIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Rathair follicle morphogenesis involved_inIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Rathair follicle morphogenesis involved_inISORGD:622281624291 PMID:21266583RGDPMID:21266583
Pla2g10Ratintestinal stem cell homeostasis involved_inIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Ratintestinal stem cell homeostasis involved_inISORGD:622281624291 PMID:27292189RGDPMID:27292189
Pla2g10Ratlipid catabolic process involved_inIEAInterPro:IPR0012111600115GO_REF:0000002InterProGO_REF:0000002
Pla2g10Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g10Ratlow-density lipoprotein particle remodeling involved_inISORGD:7364271624291 PMID:12021277RGDPMID:12021277
Pla2g10Ratlysophospholipid transport acts_upstream_of_or_withinISORGD:7364271624291 PMID:15927955RGDPMID:15927955
Pla2g10Ratmacrophage activation acts_upstream_of_or_withinISORGD:622281624291 PMID:26828067RGDPMID:26828067
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Cellular Component
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Object Symbol
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Reference
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Original Reference(s)
Pla2g10Ratacrosomal vesicle located_inISSUniProtKB:Q9QXX31600115GO_REF:0000024UniProtGO_REF:0000024
Pla2g10Ratacrosomal vesicle located_inIEAUniProtKB-SubCell:SL-00071600115GO_REF:0000044UniProtGO_REF:0000044
Pla2g10Ratacrosomal vesicle located_inISORGD:622281624291 PMID:20424324RGDPMID:20424324
Pla2g10Ratacrosomal vesicle located_inIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Ratcytoplasmic vesicle located_inIEAUniProtKB-KW:KW-09681600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g10Ratextracellular region  TAS 1357199 RGD 
Pla2g10Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g10Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Pla2g10Ratextracellular space located_inISORGD:7364271624291 PMID:21805676RGDPMID:21805676
Pla2g10Ratlysosome located_inIEAUniProtKB-SubCell:SL-01581600115GO_REF:0000044UniProtGO_REF:0000044
Pla2g10Ratlysosome located_inIEAUniProtKB-KW:KW-04581600115GO_REF:0000043UniProtGO_REF:0000043
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Molecular Function
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Object Symbol
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Reference
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Original Reference(s)
Pla2g10Rat1-alkyl-2-acetylglycerophosphocholine esterase activity enablesISSUniProtKB:O154961600115GO_REF:0000024UniProtGO_REF:0000024
Pla2g10Rat1-alkyl-2-acetylglycerophosphocholine esterase activity enablesISORGD:7364271624291 PMID:16962371RGDPMID:16962371
Pla2g10Ratcalcium ion binding enablesIEAInterPro:IPR0012111600115GO_REF:0000002InterProGO_REF:0000002
Pla2g10Ratcalcium ion binding enablesIBAMGI:1313269|PANTHER:PTN000919171|UniProtKB:P04054|UniProtKB:Q9NZK71600115GO_REF:0000033GO_CentralGO_REF:0000033
Pla2g10Ratcalcium-dependent phospholipase A2 activity enablesISSUniProtKB:O154961600115GO_REF:0000024UniProtGO_REF:0000024
Pla2g10Ratcalcium-dependent phospholipase A2 activity enablesISORGD:622281624291 PMID:12359733RGDPMID:12359733
Pla2g10Ratcalcium-dependent phospholipase A2 activity enablesIBAMGI:1341796|MGI:1347522|MGI:1349660|PANTHER:PTN000919171|RGD:3340|RGD:61949|RGD:62051|RGD:620857|UniProtKB:O15496|UniProtKB:P04054|UniProtKB:P14555|UniProtKB:Q9BZM2|UniProtKB:Q9NZK7|UniProtKB:Q9UNK41600115GO_REF:0000033GO_CentralGO_REF:0000033
Pla2g10Ratcalcium-dependent phospholipase A2 activity enablesISORGD:7364271624291 PMID:12021277, PMID:12359733, PMID:16146426, PMID:16962371RGDPMID:12021277|PMID:12359733|PMID:16146426|PMID:16962371
Pla2g10Ratcalcium-dependent phospholipase A2 activity enablesIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g10Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Pla2g10Ratphospholipase A2 activity  IDA 1582547 RGD 
Pla2g10Ratphospholipase A2 activity enablesIEARHEA:158011600115GO_REF:0000116RHEAGO_REF:0000116
Pla2g10Ratphospholipase A2 activity enablesIEAEC:3.1.1.41600115GO_REF:0000003UniProtGO_REF:0000003
Pla2g10Ratphospholipase A2 activity enablesIEAInterPro:IPR001211|InterPro:IPR016090|InterPro:IPR0364441600115GO_REF:0000002InterProGO_REF:0000002
Pla2g10Ratphospholipase A2 activity enablesIEAARBA:ARBA000285441600115GO_REF:0000117UniProtGO_REF:0000117
Pla2g10Ratphospholipase activity enablesISORGD:622281624291MGI:4412409 PMID:20844270, PMID:26828067RGDPMID:20844270|PMID:26828067
Pla2g10Ratphospholipase activity enablesIEAUniProtKB:Q9QXX3|ensembl:ENSMUSP000000233641600115GO_REF:0000107EnsemblGO_REF:0000107
Pla2g10Ratphospholipid binding enablesIBAPANTHER:PTN000919171|UniProtKB:P145551600115GO_REF:0000033GO_CentralGO_REF:0000033
Pla2g10Ratprotein binding enablesISORGD:7364271624291UniProtKB:A5D8V6|UniProtKB:A8MQ03|UniProtKB:A8MV65-2|UniProtKB:O14633|UniProtKB:O14964|UniProtKB:O43593|UniProtKB:O43711|UniProtKB:O60336|UniProtKB:O75593|UniProtKB:O75716|UniProtKB:O95817|UniProtKB:O95947|UniProtKB:P09234|UniProtKB:P21145|UniProtKB:P21549|UniProtKB:P29972|UniProtKB:P31273|UniProtKB:P32242|UniProtKB:P54253|UniProtKB:P78337|UniProtKB:Q01974|UniProtKB:Q02930-3|UniProtKB:Q03989|UniProtKB:Q0VD86|UniProtKB:Q15319|UniProtKB:Q5T749|UniProtKB:Q5T751|UniProtKB:Q5T7P2|UniProtKB:Q5TA79|UniProtKB:Q5TA82|UniProtKB:Q6P1W5|UniProtKB:Q6PEX3|UniProtKB:Q7Z5V6-2|UniProtKB:Q7Z699|UniProtKB:Q86UR1-2|UniProtKB:Q8IUC1|UniProtKB:Q8NEC5|UniProtKB:Q8WU58|UniProtKB:Q92734|UniProtKB:Q96HA8|UniProtKB:Q96HB5|UniProtKB:Q96K80|UniProtKB:Q99932-2|UniProtKB:Q9BWX5|UniProtKB:Q9BXY8|UniProtKB:Q9ULV5-2|UniProtKB:Q9Y223-2 PMID:28514442, PMID:32296183, PMID:32814053, PMID:33961781RGDPMID:28514442|PMID:32296183|PMID:32814053|PMID:33961781
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Imported Annotations - KEGG (archival)

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Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Expression and location of mRNAs encoding multiple forms of secretory phospholipase A2 in the rat retina. Kolko M, etal., J Neurosci Res 2004 Aug 15;77(4):517-24.
5. Neuronal expression and neuritogenic action of group X secreted phospholipase A2. Masuda S, etal., J Biol Chem. 2005 Jun 17;280(24):23203-14. Epub 2005 Mar 21.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
12. On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes. Valentin E, etal., J Biol Chem 1999 Oct 29;274(44):31195-202.
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PMID:15927955   PMID:18511424   PMID:20439489   PMID:20844270   PMID:21805676  



Pla2g10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8102,104,927 - 2,117,998 (-)NCBIGRCr8
mRatBN7.2101,597,761 - 1,610,822 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl101,597,761 - 1,609,000 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx106,294,586 - 6,305,824 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01034,260,010 - 34,271,250 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0101,612,004 - 1,623,245 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0101,509,732 - 1,520,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl101,509,732 - 1,520,970 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010406,661 - 417,899 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41026,035 - 37,273 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11026,034 - 37,266 (-)NCBI
Celera10658,651 - 669,889 (-)NCBICelera
Cytogenetic Map10q11NCBI
PLA2G10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381614,672,548 - 14,701,850 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1614,672,548 - 14,694,308 (-)EnsemblGRCh38hg38GRCh38
GRCh371614,766,405 - 14,788,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361614,673,906 - 14,696,027 (-)NCBINCBI36Build 36hg18NCBI36
Build 341614,673,907 - 14,696,027NCBI
Celera1614,943,182 - 14,965,293 (-)NCBICelera
Cytogenetic Map16p13.12-p13.11NCBI
HuRef1614,685,697 - 14,707,807 (-)NCBIHuRef
CHM1_11614,766,236 - 14,788,360 (-)NCBICHM1_1
T2T-CHM13v2.01614,710,083 - 14,732,094 (-)NCBIT2T-CHM13v2.0
Pla2g10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391613,532,921 - 13,548,863 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1613,532,921 - 13,548,847 (-)EnsemblGRCm39 Ensembl
GRCm381613,715,057 - 13,731,094 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1613,715,057 - 13,730,983 (-)EnsemblGRCm38mm10GRCm38
MGSCv371613,715,155 - 13,730,678 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361613,628,640 - 13,644,163 (-)NCBIMGSCv36mm8
Celera1614,319,504 - 14,335,040 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.5NCBI
Pla2g10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554424,208,575 - 4,225,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554424,208,497 - 4,225,893 (+)NCBIChiLan1.0ChiLan1.0
LOC100990946
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21815,204,875 - 15,232,910 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11618,987,730 - 19,015,721 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01613,600,152 - 13,622,629 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11615,021,025 - 15,043,782 (-)NCBIpanpan1.1PanPan1.1panPan2
PLA2G10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1628,573,239 - 28,591,714 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl628,574,387 - 28,591,703 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha629,936,319 - 29,954,796 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0628,736,378 - 28,754,847 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl628,736,238 - 28,754,865 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1628,539,400 - 28,557,862 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0628,427,844 - 28,446,114 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0628,835,005 - 28,853,467 (+)NCBIUU_Cfam_GSD_1.0
LOC101960864
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344114,743,588 - 114,759,931 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365012,841,660 - 2,854,952 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365012,841,209 - 2,857,570 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110259864
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl37,623,312 - 7,642,002 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.137,623,326 - 7,641,061 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pla2g10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247823,870,940 - 3,887,426 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247823,871,034 - 3,887,476 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pla2g10
35 total Variants

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:48
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000004237
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 6 12 46 51 52 23 20 23 3 127 48 31 42 60 29


1 to 18 of 18 rows
RefSeq Transcripts NM_017176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF166100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY651029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 18 of 18 rows

Ensembl Acc Id: ENSRNOT00000004237   ⟹   ENSRNOP00000004237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl101,597,761 - 1,609,000 (-)Ensembl
Rnor_6.0 Ensembl101,509,732 - 1,520,970 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101842   ⟹   ENSRNOP00000092711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl101,597,761 - 1,606,701 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103030   ⟹   ENSRNOP00000080329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl101,598,246 - 1,609,000 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114578   ⟹   ENSRNOP00000093943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl101,597,761 - 1,607,200 (-)Ensembl
RefSeq Acc Id: NM_017176   ⟹   NP_058872
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,172 (-)NCBI
mRatBN7.2101,597,761 - 1,609,007 (-)NCBI
Rnor_6.0101,509,732 - 1,520,970 (-)NCBI
Rnor_5.010406,661 - 417,899 (-)NCBI
RGSC_v3.41026,035 - 37,273 (-)RGD
Celera10658,651 - 669,889 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085716   ⟹   XP_038941644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,698 (-)NCBI
mRatBN7.2101,597,761 - 1,609,529 (-)NCBI
RefSeq Acc Id: XM_039085719   ⟹   XP_038941647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,691 (-)NCBI
mRatBN7.2101,597,761 - 1,609,529 (-)NCBI
RefSeq Acc Id: XM_039085721   ⟹   XP_038941649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,698 (-)NCBI
mRatBN7.2101,597,761 - 1,609,529 (-)NCBI
RefSeq Acc Id: XM_039085722   ⟹   XP_038941650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,698 (-)NCBI
mRatBN7.2101,597,761 - 1,609,529 (-)NCBI
RefSeq Acc Id: XM_039085724   ⟹   XP_038941652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,199 (-)NCBI
mRatBN7.2101,597,761 - 1,609,032 (-)NCBI
RefSeq Acc Id: XM_039085726   ⟹   XP_038941654
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,199 (-)NCBI
mRatBN7.2101,597,761 - 1,609,040 (-)NCBI
RefSeq Acc Id: XM_039085731   ⟹   XP_038941659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,182 (-)NCBI
mRatBN7.2101,597,761 - 1,609,021 (-)NCBI
RefSeq Acc Id: XM_063268802   ⟹   XP_063124872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,698 (-)NCBI
RefSeq Acc Id: XM_063268803   ⟹   XP_063124873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,117,998 (-)NCBI
RefSeq Acc Id: XM_063268804   ⟹   XP_063124874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,691 (-)NCBI
RefSeq Acc Id: XM_063268805   ⟹   XP_063124875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,058 (-)NCBI
RefSeq Acc Id: XM_063268807   ⟹   XP_063124877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,691 (-)NCBI
RefSeq Acc Id: XM_063268808   ⟹   XP_063124878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,104,927 - 2,116,079 (-)NCBI
1 to 5 of 18 rows
1 to 5 of 18 rows
RefSeq Acc Id: NP_058872   ⟸   NM_017176
- Peptide Label: precursor
- UniProtKB: Q9QZT3 (UniProtKB/Swiss-Prot),   G3V6E2 (UniProtKB/TrEMBL),   A6K4E7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004237   ⟸   ENSRNOT00000004237
RefSeq Acc Id: XP_038941647   ⟸   XM_039085719
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941649   ⟸   XM_039085721
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941650   ⟸   XM_039085722
- Peptide Label: isoform X2
Phospholipase A2

Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZT3-F1-model_v2 AlphaFold Q9QZT3 1-151 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696926
Promoter ID:EPDNEW_R7451
Type:multiple initiation site
Name:Pla2g10_1
Description:phospholipase A2, group X
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0101,520,977 - 1,521,037EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-26223 BioCyc
Ensembl Genes ENSRNOG00000003164 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000004237 ENTREZGENE
Gene3D-CATH 1.20.90.10 UniProtKB/Swiss-Prot
InterPro PLipase_A2 UniProtKB/Swiss-Prot
  PLipase_A2_Asp_AS UniProtKB/Swiss-Prot
  PLipase_A2_dom UniProtKB/Swiss-Prot
  PLipase_A2_dom_sf UniProtKB/Swiss-Prot
  PLipase_A2_His_AS UniProtKB/Swiss-Prot
KEGG Report rno:29359 UniProtKB/Swiss-Prot
NCBI Gene 29359 ENTREZGENE
PANTHER GROUP 10 SECRETORY PHOSPHOLIPASE A2 UniProtKB/Swiss-Prot
  PTHR11716 UniProtKB/Swiss-Prot
Pfam Phospholip_A2_1 UniProtKB/Swiss-Prot
PhenoGen Pla2g10 PhenoGen
PRINTS PHPHLIPASEA2 UniProtKB/Swiss-Prot
PROSITE PA2_ASP UniProtKB/Swiss-Prot
  PA2_HIS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003164 RatGTEx
SMART PA2c UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48619 UniProtKB/Swiss-Prot
TIGR TC202847
UniProt A0A8I6ALE8_RAT UniProtKB/TrEMBL
  A0A8I6AW05_RAT UniProtKB/TrEMBL
  A0A8I6G4E1_RAT UniProtKB/TrEMBL
  A6K4E7 ENTREZGENE, UniProtKB/TrEMBL
  A6K4E8_RAT UniProtKB/TrEMBL
  G3V6E2 ENTREZGENE, UniProtKB/TrEMBL
  PA2GX_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Pla2g10  phospholipase A2, group X    phospholipase A2, group 10  Name updated 1299863 APPROVED
2002-06-10 Pla2g10  phospholipase A2, group 10      Name updated 70584 APPROVED

Note Type Note Reference