Pla2g10 (phospholipase A2 group X) - Rat Genome Database

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Gene: Pla2g10 (phospholipase A2 group X) Chinchilla lanigera
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Symbol: Pla2g10
Name: phospholipase A2 group X
RGD ID: 9060830
Description: ENCODES a protein that exhibits 1-alkyl-2-acetylglycerophosphocholine esterase activity (ortholog); calcium-dependent phospholipase A2 activity (ortholog); phospholipase A2 activity (ortholog); INVOLVED IN axon guidance (ortholog); cellular response to leukemia inhibitory factor (ortholog); cholesterol homeostasis (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN acrosomal vesicle (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: group 10 secretory phospholipase A2; phospholipase A2, group X
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554424,208,575 - 4,225,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554424,208,497 - 4,225,893 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pla2g10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554424,208,575 - 4,225,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554424,208,497 - 4,225,893 (+)NCBIChiLan1.0ChiLan1.0
PLA2G10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381614,672,548 - 14,701,850 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1614,672,548 - 14,694,308 (-)EnsemblGRCh38hg38GRCh38
GRCh371614,766,405 - 14,788,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361614,673,906 - 14,696,027 (-)NCBINCBI36Build 36hg18NCBI36
Build 341614,673,907 - 14,696,027NCBI
Celera1614,943,182 - 14,965,293 (-)NCBICelera
Cytogenetic Map16p13.12-p13.11NCBI
HuRef1614,685,697 - 14,707,807 (-)NCBIHuRef
CHM1_11614,766,236 - 14,788,360 (-)NCBICHM1_1
T2T-CHM13v2.01614,710,083 - 14,732,094 (-)NCBIT2T-CHM13v2.0
Pla2g10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391613,532,921 - 13,548,863 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1613,532,921 - 13,548,847 (-)EnsemblGRCm39 Ensembl
GRCm381613,715,057 - 13,731,094 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1613,715,057 - 13,730,983 (-)EnsemblGRCm38mm10GRCm38
MGSCv371613,715,155 - 13,730,678 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361613,628,640 - 13,644,163 (-)NCBIMGSCv36mm8
Celera1614,319,504 - 14,335,040 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.5NCBI
Pla2g10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8102,104,927 - 2,117,998 (-)NCBIGRCr8
mRatBN7.2101,597,761 - 1,610,822 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl101,597,761 - 1,609,000 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx106,294,586 - 6,305,824 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01034,260,010 - 34,271,250 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0101,612,004 - 1,623,245 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0101,509,732 - 1,520,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl101,509,732 - 1,520,970 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010406,661 - 417,899 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41026,035 - 37,273 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11026,034 - 37,266 (-)NCBI
Celera10658,651 - 669,889 (-)NCBICelera
Cytogenetic Map10q11NCBI
LOC100990946
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21815,204,875 - 15,232,910 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11618,987,730 - 19,015,721 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01613,600,152 - 13,622,629 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11615,021,025 - 15,043,782 (-)NCBIpanpan1.1PanPan1.1panPan2
PLA2G10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1628,573,239 - 28,591,714 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl628,574,387 - 28,591,703 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha629,936,319 - 29,954,796 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0628,736,378 - 28,754,847 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1628,539,400 - 28,557,862 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0628,427,844 - 28,446,114 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0628,835,005 - 28,853,467 (+)NCBIUU_Cfam_GSD_1.0
LOC101960864
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344114,743,588 - 114,759,931 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365012,841,660 - 2,854,952 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365012,841,209 - 2,857,570 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110259864
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl37,623,312 - 7,642,002 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.137,623,326 - 7,641,061 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pla2g10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247823,870,940 - 3,887,426 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247823,871,034 - 3,887,476 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000020386   ⟹   ENSCLAP00000020191
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554424,208,575 - 4,225,834 (+)Ensembl
RefSeq Acc Id: XM_005391132   ⟹   XP_005391189
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554424,208,497 - 4,225,893 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005391189 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020191
  ENSCLAP00000020191.1
RefSeq Acc Id: XP_005391189   ⟸   XM_005391132
- UniProtKB: A0A8C2VT84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000020191   ⟸   ENSCLAT00000020386
Protein Domains
Phospholipase A2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013831 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020386 ENTREZGENE
  ENSCLAT00000020386.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.90.10 UniProtKB/TrEMBL
InterPro PLipase_A2 UniProtKB/TrEMBL
  PLipase_A2_Asp_AS UniProtKB/TrEMBL
  PLipase_A2_dom UniProtKB/TrEMBL
  PLipase_A2_dom_sf UniProtKB/TrEMBL
  PLipase_A2_His_AS UniProtKB/TrEMBL
NCBI Gene Pla2g10 ENTREZGENE
PANTHER GROUP 10 SECRETORY PHOSPHOLIPASE A2 UniProtKB/TrEMBL
  PTHR11716 UniProtKB/TrEMBL
Pfam Phospholip_A2_1 UniProtKB/TrEMBL
PRINTS PHPHLIPASEA2 UniProtKB/TrEMBL
PROSITE PA2_ASP UniProtKB/TrEMBL
  PA2_HIS UniProtKB/TrEMBL
SMART PA2c UniProtKB/TrEMBL
Superfamily-SCOP SSF48619 UniProtKB/TrEMBL
UniProt A0A8C2VT84 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Pla2g10  phospholipase A2 group X    phospholipase A2, group X  Symbol and/or name change 5135510 APPROVED