Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:T cell mediated cytotoxicity
go back to main search page
Accession:GO:0001913 term browser browse the term
Definition:The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
Comment:Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in the induction of apoptosis in the target cell. Note that both CD4 and CD8 positive T cells can mediate apoptosis of target cells, independently of their definition as 'helper' T cells or not.
Synonyms:exact_synonym: T cell mediated apoptosis;   T cell mediated cell death;   T cell mediated cell killing;   T-lymphocyte mediated cytotoxicity
 related_synonym: T cell mediated cytolysis



show annotations for term's descendants           Sort by:
T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin acts_upstream_of ISO (MGI:3611636|PMID:16299293) RGD PMID:16299293 MGI:3611636 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Cadm1 cell adhesion molecule 1 NOT|involved_in ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule NOT|involved_in ISO (PMID:15811952) RGD PMID:15811952 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343
JBrowse link
G Ctsc cathepsin C involved_in ISO UniProtKB:P49935 (MGI:4838939|PMID:20435891) RGD PMID:20435891 MGI:4838939 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctsh cathepsin H involved_in ISS
ISO
GO_REF:0000024
UniProtKB:P97821 (MGI:4838939|PMID:20435891)
UniProt
RGD
PMID:20435891 GO_REF:0000024 MGI:4838939 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:4359722 (MGI:7294920|PMID:35482418)
GO_REF:0000107
RGD
Ensembl
PMID:35482418 GO_REF:0000107 MGI:7294920 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5605955|PMID:12763482)
UniProt
RGD
PMID:12763482 GO_REF:0000024 MGI:5605955 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733
JBrowse link
G Gfus GDP-L-fucose synthase acts_upstream_of_or_within ISO (MGI:58355|PMID:2568889) RGD PMID:2568889 MGI:58355 NCBI chr 7:107,612,087...107,617,005
Ensembl chr 7:107,612,094...107,616,948
JBrowse link
G Gzmb granzyme B acts_upstream_of_or_within ISO MGI:1857156 (MGI:3665503|PMID:16618603) RGD PMID:16618603 MGI:3665503 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
JBrowse link
G Gzmm granzyme M involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3531039|PMID:15454490)
Ensembl
RGD
PMID:15454490 GO_REF:0000107 MGI:3531039 NCBI chr 7:10,011,065...10,016,841
Ensembl chr 7:10,011,066...10,016,665
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1857299 (MGI:2675193|PMID:12944494)
GO_REF:0000107
RGD
Ensembl
PMID:12944494 GO_REF:0000107 MGI:2675193 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of ISO MGI:1857198 (MGI:893318|PMID:9215624) RGD PMID:9215624 MGI:893318 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10426993) RGD PMID:10426993 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of ISO MGI:3042190 (MGI:3040567|PMID:14761980) RGD PMID:14761980 MGI:3040567 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta acts_upstream_of
involved_in
ISO
IEA
MGI:2181294 (MGI:3772519|PMID:18097009)
GO_REF:0000107
RGD
Ensembl
PMID:18097009 GO_REF:0000107 MGI:3772519 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Prf1 perforin 1 acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(MGI:3531039|PMID:15454490)
GO_REF:0000033
GO_REF:0000118
(MGI:5285144|PMID:21037563), (MGI:6830380|PMID:26306037), (MGI:69649|PMID:7972104)
GO_REF:0000107
RGD
GO_Central
TreeGrafter
Ensembl
PMID:7972104 PMID:15454490 PMID:21037563 PMID:26306037 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:3531039 MGI:5285144 MGI:6830380 MGI:69649 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Raet1e retinoic acid early transcript 1E acts_upstream_of_or_within ISO (MGI:3037535|PMID:11567106) RGD PMID:11567106 MGI:3037535 NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 acts_upstream_of ISO (MGI:50291|PMID:1538753) RGD PMID:1538753 MGI:50291 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:7504010) RGD PMID:7504010 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
JBrowse link
G Serpinb9 serpin family B member 9 acts_upstream_of_or_within ISO MGI:3687210 (MGI:3665503|PMID:16618603) RGD PMID:16618603 MGI:3665503 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080) RGD PMID:23042080 MGI:5460953 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of
involved_in
ISO
IEA
(MGI:3611636|PMID:16299293), (MGI:50291|PMID:1538753)
GO_REF:0000107
RGD
Ensembl
PMID:1538753 PMID:16299293 GO_REF:0000107 MGI:3611636 MGI:50291 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (MGI:893318|PMID:9215624) RGD PMID:9215624 MGI:893318 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206) RGD PMID:9485206 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IEA
ISS
(PMID:9485206)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:9485206 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2181294 (MGI:3772519|PMID:18097009)
GO_REF:0000107
RGD
Ensembl
PMID:18097009 GO_REF:0000107 MGI:3772519 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO
GO_REF:0000024
(MGI:3654612|PMID:9725213)
UniProt
RGD
PMID:9725213 GO_REF:0000024 MGI:3654612 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,242 JBrowse link
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07000137.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:1,307,185...1,308,310 JBrowse link
G AABR07000147.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G AABR07001348.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:39,668,472...39,670,153 JBrowse link
G AABR07044308.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr20:1,789,779...1,793,115 JBrowse link
G AABR07044308.2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr20:1,768,641...1,772,357 JBrowse link
G AABR07044362.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr20:2,630,622...2,634,751 JBrowse link
G AABR07044383.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr20:3,403,777...3,436,874 JBrowse link
G AABR07044397.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr20:2,496,605...2,497,428 JBrowse link
G AC120486.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO (MGI:3611636|PMID:16299293) RGD PMID:16299293 MGI:3611636 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
(MGI:2180705|PMID:10201995)
GO_REF:0000118
GO_REF:0000033
RGD
TreeGrafter
GO_Central
PMID:10201995 GO_REF:0000033 GO_REF:0000118 MGI:2180705 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cyrib CYFIP related Rac1 interactor B involved_in ISO (MGI:5432330|PMID:22522492) RGD PMID:22522492 MGI:5432330 NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686
JBrowse link
G ENSRNOG00000064836 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr20:2,606,621...2,618,153 JBrowse link
G ENSRNOG00000069480 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr20:3,310,825...3,421,372 JBrowse link
G Fadd Fas associated via death domain involved_in ISS
ISO
GO_REF:0000024
(MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G H2-M10.6l histocompatibility 2, M region locus 10.6 like involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:1,958,270...1,965,247
Ensembl chr20:1,925,049...1,966,105
JBrowse link
G H60al histocompatibility 60a like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:1,382,896...1,386,846 JBrowse link
G Hfe homeostatic iron regulator involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IDA prevention of heat shock-induced resistance to CTL-mediated killing RGD PMID:10679071 RGD:1298959 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:8871636 RGD:10059395 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA
(PMID:1674604), (PMID:2204066)
GO_REF:0000107
RGD
Ensembl
PMID:1674604 PMID:2204066 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B involved_in ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Micb MHC class I polypeptide-related sequence B involved_in IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 1:78,495,779...78,513,030
Ensembl chr 1:78,495,779...78,512,827
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G Mr1 major histocompatibility complex, class I-related involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:3042190 (MGI:3040567|PMID:14761980) RGD PMID:14761980 MGI:3040567 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (MGI:55923|PMID:6233370) RGD PMID:6233370 MGI:55923 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Raet1l retinoic acid early transcript 1L involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410
JBrowse link
G RT1-A RT1 class I, locus A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G RT1-A1 RT1 class Ia, locus A1 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:11773898 GO_REF:0000033, RGD:2313503 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:50291|PMID:1538753)
GO_REF:0000033
(PMID:20195504), (PMID:25631937)
RGD
GO_Central
PMID:1538753 PMID:20195504 PMID:25631937 GO_REF:0000033 MGI:50291 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE1 RT1 class I, locus1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,555,779...3,559,487
Ensembl chr20:3,555,782...3,559,486
JBrowse link
G RT1-CE11 RT1 class I, locus CE11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362
JBrowse link
G RT1-CE14 RT1 class I, locus CE14 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134
JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:22031944), (PMID:2420472), (PMID:25631937), (PMID:8805302) RGD PMID:2420472 PMID:8805302 PMID:22031944 PMID:25631937 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
JBrowse link
G RT1-CE2 RT1 class I, locus CE2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790
JBrowse link
G RT1-CE3 RT1 class I, locus CE3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO
IBA
(PMID:23851683)
GO_REF:0000033
RGD
GO_Central
PMID:23851683 GO_REF:0000033 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-CE7 RT1 class I, locus CE7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,434,205...3,437,152 JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:29884618) RGD PMID:29884618 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G RT1-M1-2 RT1 class I, locus M1, gene 2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:1,909,506...1,913,423
Ensembl chr20:1,910,656...1,917,936
JBrowse link
G RT1-M1-4 RT1 class I, locus M1, gene 4 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:1,891,365...1,893,585
Ensembl chr20:1,889,164...1,893,815
JBrowse link
G RT1-M1-5 RT1 class I, M1, gene 5 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:1,858,608...1,860,708
Ensembl chr20:1,811,604...1,860,708
JBrowse link
G RT1-M10-1 RT1 class I, locus M10, gene 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:1,986,817...1,988,908
Ensembl chr20:1,986,788...2,020,117
JBrowse link
G RT1-M2 RT1 class Ib, locus M2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:978,918...981,510
Ensembl chr20:978,935...981,723
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3701255 (MGI:3611636|PMID:16299293), (MGI:3700863|PMID:16461341), (MGI:3700871|PMID:16476767), (MGI:52901|PMID:8464890)
GO_REF:0000033
RGD
GO_Central
PMID:8464890 PMID:16299293 PMID:16461341 PMID:16476767 GO_REF:0000033 MGI:3611636 MGI:3700863 MGI:3700871 MGI:52901 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G RT1-M5 RT1 class Ib, locus M5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,546,496...1,548,948
Ensembl chr20:1,546,511...1,548,775
JBrowse link
G RT1-M6-2 RT1 class I, locus M6, gene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,583,267...1,587,099
Ensembl chr20:1,583,299...1,586,215
JBrowse link
G RT1-N1 RT1 class Ib, locus N1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G RT1-N2 RT1 class Ib, locus N2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,641,157...2,645,439
Ensembl chr20:2,641,202...2,644,900
JBrowse link
G RT1-N3 RT1 class Ib, locus N3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,659,132...2,665,536
Ensembl chr20:2,661,584...2,665,530
JBrowse link
G RT1-O1 RT1 class Ib, locus O1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:2,655,116...2,657,520
Ensembl chr20:2,655,116...2,657,520
JBrowse link
G RT1-O1l1 RT1 class Ib, locus O1 like 1 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr20:2,624,073...2,658,023
Ensembl chr20:2,623,953...2,692,081
JBrowse link
G RT1-S2 RT1 class Ib, locus S2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:2,650,233...2,651,654
Ensembl chr20:2,649,964...2,652,027
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G RT1-T24-1 RT1 class I, locus T24, gene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,761,495...2,774,871
Ensembl chr20:2,718,279...2,776,154
JBrowse link
G RT1-T24-3 RT1 class I, locus T24, gene 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,718,210...2,730,604
Ensembl chr20:2,718,279...2,776,154
JBrowse link
G RT1-T24-4 RT1 class I, locus T24, gene 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511
JBrowse link
G Stx7 syntaxin 7 involved_in ISO
IEA
(PMID:21438968)
GO_REF:0000107
RGD
Ensembl
PMID:21438968 GO_REF:0000107 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in
ISO
IEA
IDA
(MGI:3611636|PMID:16299293), (MGI:50291|PMID:1538753)
GO_REF:0000107
PMID:1758495
RGD
Ensembl
PMID:1538753 PMID:16299293 PMID:1758495 GO_REF:0000107 MGI:3611636 MGI:50291, RGD:1299069 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) RGD PMID:18832695 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329
JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA
(PMID:31959982)
GO_REF:0000107
RGD
Ensembl
PMID:31959982 GO_REF:0000107 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635
JBrowse link
regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA
(PMID:22473704)
GO_REF:0000107
RGD
Ensembl
PMID:22473704 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q61160 (MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:15039383)
GO_REF:0000033
RGD
GO_Central
PMID:15039383 GO_REF:0000033 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:15039383) RGD PMID:15039383 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:1402688), (PMID:17189421), (PMID:20364150) RGD PMID:1402688 PMID:17189421 PMID:20364150 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20350
    cellular process 18813
      cell killing 246
        leukocyte mediated cytotoxicity 183
          T cell mediated cytotoxicity 90
            T cell mediated cytotoxicity directed against tumor cell target + 4
            cytotoxic T cell degranulation + 4
            negative regulation of T cell mediated cytotoxicity + 9
            positive regulation of T cell mediated cytotoxicity + 66
            regulation of T cell mediated cytotoxicity + 75
Path 2
Term Annotations click to browse term
  biological_process 20350
    immune system process 2980
      immune effector process 827
        leukocyte mediated immunity 580
          lymphocyte mediated immunity 462
            T cell mediated immunity 163
              T cell mediated cytotoxicity 90
                T cell mediated cytotoxicity directed against tumor cell target + 4
                cytotoxic T cell degranulation + 4
                negative regulation of T cell mediated cytotoxicity + 9
                positive regulation of T cell mediated cytotoxicity + 66
                regulation of T cell mediated cytotoxicity + 75
paths to the root